LOCUS       DARYLD010000001        84004 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYLD010000001 DARYLD010000000
VERSION     DARYLD010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 84004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84004
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..376
                     /locus_tag="TU651_000001"
     CDS             <1..376
                     /locus_tag="TU651_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL0896050.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TU651_000002"
                     /pseudo
     CDS             692..933
                     /locus_tag="TU651_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TU651_000003"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TU651_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL0896051.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TU651_000004"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TU651_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL0896052.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TU651_000005"
     CDS             6494..6823
                     /locus_tag="TU651_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0896053.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TU651_000006"
     CDS             6827..7261
                     /locus_tag="TU651_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL0896054.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TU651_000007"
     CDS             7263..7547
                     /locus_tag="TU651_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0896055.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TU651_000008"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TU651_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU651_000009"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TU651_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL0896056.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TU651_000010"
     CDS             10025..10675
                     /locus_tag="TU651_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL0896057.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TU651_000011"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TU651_000011"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0896058.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TU651_000012"
     CDS             12073..12813
                     /locus_tag="TU651_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL0896059.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TU651_000013"
     CDS             12810..14528
                     /locus_tag="TU651_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0896060.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HSKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TU651_000014"
     CDS             14567..15655
                     /locus_tag="TU651_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL0896061.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TU651_000015"
     CDS             15670..16374
                     /locus_tag="TU651_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL0896062.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TU651_000016"
     CDS             16634..17122
                     /locus_tag="TU651_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL0896063.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TU651_000017"
     CDS             complement(17632..18105)
                     /locus_tag="TU651_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0896064.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TU651_000018"
     CDS             18246..18926
                     /locus_tag="TU651_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0896065.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TU651_000019"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TU651_000019"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL0896066.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TU651_000020"
     CDS             20440..20871
                     /locus_tag="TU651_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896067.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TU651_000021"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TU651_000021"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL0896068.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TU651_000022"
     CDS             22061..23554
                     /locus_tag="TU651_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL0896069.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TU651_000023"
     CDS             23571..24902
                     /locus_tag="TU651_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL0896070.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TU651_000024"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TU651_000024"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL0896071.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
     gene            26090..27082
                     /locus_tag="TU651_000025"
                     /pseudo
     CDS             26090..27082
                     /locus_tag="TU651_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
     gene            27254..27793
                     /gene="rsmD"
                     /locus_tag="TU651_000026"
     CDS             27254..27793
                     /gene="rsmD"
                     /locus_tag="TU651_000026"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL0896072.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            27783..28283
                     /gene="coaD"
                     /locus_tag="TU651_000027"
     CDS             27783..28283
                     /gene="coaD"
                     /locus_tag="TU651_000027"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL0896073.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            28261..29298
                     /locus_tag="TU651_000028"
     CDS             28261..29298
                     /locus_tag="TU651_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL0896074.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            29860..30474
                     /locus_tag="TU651_000029"
     CDS             29860..30474
                     /locus_tag="TU651_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL0896075.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            30478..31560
                     /gene="rlmN"
                     /locus_tag="TU651_000030"
     CDS             30478..31560
                     /gene="rlmN"
                     /locus_tag="TU651_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL0896076.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            32842..33372
                     /locus_tag="TU651_000031"
     CDS             32842..33372
                     /locus_tag="TU651_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL0896077.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            33745..33978
                     /locus_tag="TU651_000032"
     CDS             33745..33978
                     /locus_tag="TU651_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL0896078.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            33953..34924
                     /locus_tag="TU651_000033"
     CDS             33953..34924
                     /locus_tag="TU651_000033"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL0896079.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            34934..35314
                     /locus_tag="TU651_000034"
     CDS             34934..35314
                     /locus_tag="TU651_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL0896080.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            35710..37551
                     /gene="typA"
                     /locus_tag="TU651_000035"
     CDS             35710..37551
                     /gene="typA"
                     /locus_tag="TU651_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL0896081.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            37633..37887
                     /locus_tag="TU651_000036"
     CDS             37633..37887
                     /locus_tag="TU651_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL0896082.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            38033..39394
                     /locus_tag="TU651_000037"
     CDS             38033..39394
                     /locus_tag="TU651_000037"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL0896083.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            39391..40473
                     /locus_tag="TU651_000038"
     CDS             39391..40473
                     /locus_tag="TU651_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL0896084.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            40474..41664
                     /locus_tag="TU651_000039"
     CDS             40474..41664
                     /locus_tag="TU651_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL0896085.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            41876..43240
                     /gene="ftsA"
                     /locus_tag="TU651_000040"
     CDS             41876..43240
                     /gene="ftsA"
                     /locus_tag="TU651_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL0896086.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU651_000041"
     CDS             43264..44592
                     /gene="ftsZ"
                     /locus_tag="TU651_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL0896087.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            44595..45266
                     /locus_tag="TU651_000042"
     CDS             44595..45266
                     /locus_tag="TU651_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL0896088.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            45279..45941
                     /locus_tag="TU651_000043"
     CDS             45279..45941
                     /locus_tag="TU651_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL0896089.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            45946..46203
                     /locus_tag="TU651_000044"
     CDS             45946..46203
                     /locus_tag="TU651_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL0896090.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            46200..46994
                     /locus_tag="TU651_000045"
     CDS             46200..46994
                     /locus_tag="TU651_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL0896091.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            47004..47759
                     /locus_tag="TU651_000046"
     CDS             47004..47759
                     /locus_tag="TU651_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL0896092.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            48030..50828
                     /locus_tag="TU651_000047"
     CDS             48030..50828
                     /locus_tag="TU651_000047"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL0896093.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(51306..51608)
                     /locus_tag="TU651_000048"
     CDS             complement(51306..51608)
                     /locus_tag="TU651_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL0896094.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(51670..52119)
                     /locus_tag="TU651_000049"
     CDS             complement(51670..52119)
                     /locus_tag="TU651_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0896095.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(52279..54531)
                     /locus_tag="TU651_000050"
     CDS             complement(52279..54531)
                     /locus_tag="TU651_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0896096.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            54813..55043
                     /locus_tag="TU651_000051"
     CDS             54813..55043
                     /locus_tag="TU651_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL0896097.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(55525..56463)
                     /locus_tag="TU651_000052"
     CDS             complement(55525..56463)
                     /locus_tag="TU651_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0896098.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            56805..57488
                     /locus_tag="TU651_000053"
     CDS             56805..57488
                     /locus_tag="TU651_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0896099.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            57490..58227
                     /locus_tag="TU651_000054"
     CDS             57490..58227
                     /locus_tag="TU651_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0896100.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            58671..60365
                     /locus_tag="TU651_000055"
     CDS             58671..60365
                     /locus_tag="TU651_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0896101.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            60477..61331
                     /locus_tag="TU651_000056"
     CDS             60477..61331
                     /locus_tag="TU651_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL0896102.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            61328..62182
                     /locus_tag="TU651_000057"
     CDS             61328..62182
                     /locus_tag="TU651_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL0896103.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            62466..63806
                     /locus_tag="TU651_000058"
     CDS             62466..63806
                     /locus_tag="TU651_000058"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL0896104.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            63784..63999
                     /locus_tag="TU651_000059"
     CDS             63784..63999
                     /locus_tag="TU651_000059"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL0896105.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            63999..64868
                     /locus_tag="TU651_000060"
     CDS             63999..64868
                     /locus_tag="TU651_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL0896106.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            64861..65688
                     /locus_tag="TU651_000061"
     CDS             64861..65688
                     /locus_tag="TU651_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL0896107.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            65675..66145
                     /locus_tag="TU651_000062"
     CDS             65675..66145
                     /locus_tag="TU651_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0896108.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            66163..67824
                     /gene="recN"
                     /locus_tag="TU651_000063"
     CDS             66163..67824
                     /gene="recN"
                     /locus_tag="TU651_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL0896109.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVVAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            68045..68917
                     /locus_tag="TU651_000064"
     CDS             68045..68917
                     /locus_tag="TU651_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0896110.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            69055..69906
                     /locus_tag="TU651_000065"
     CDS             69055..69906
                     /locus_tag="TU651_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0896111.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            69899..70741
                     /locus_tag="TU651_000066"
     CDS             69899..70741
                     /locus_tag="TU651_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL0896112.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            70719..71306
                     /locus_tag="TU651_000067"
     CDS             70719..71306
                     /locus_tag="TU651_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL0896113.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            71404..71679
                     /locus_tag="TU651_000068"
     CDS             71404..71679
                     /locus_tag="TU651_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL0896114.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(71740..72444)
                     /locus_tag="TU651_000069"
     CDS             complement(71740..72444)
                     /locus_tag="TU651_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL0896115.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(72755..73963)
                     /locus_tag="TU651_000070"
     CDS             complement(72755..73963)
                     /locus_tag="TU651_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0896116.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(74018..74911)
                     /locus_tag="TU651_000071"
     CDS             complement(74018..74911)
                     /locus_tag="TU651_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0896117.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            75280..75453
                     /locus_tag="TU651_000072"
     CDS             75280..75453
                     /locus_tag="TU651_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896118.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(75498..76433)
                     /locus_tag="TU651_000073"
     CDS             complement(75498..76433)
                     /locus_tag="TU651_000073"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL0896119.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            76676..77371
                     /locus_tag="TU651_000074"
     CDS             76676..77371
                     /locus_tag="TU651_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL0896120.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            77480..78001
                     /locus_tag="TU651_000075"
     CDS             77480..78001
                     /locus_tag="TU651_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL0896121.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            78396..78935
                     /locus_tag="TU651_000076"
     CDS             78396..78935
                     /locus_tag="TU651_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896122.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            79074..79844
                     /locus_tag="TU651_000077"
     CDS             79074..79844
                     /locus_tag="TU651_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL0896123.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            79956..82010
                     /locus_tag="TU651_000078"
     CDS             79956..82010
                     /locus_tag="TU651_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL0896124.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            82022..82618
                     /gene="recR"
                     /locus_tag="TU651_000079"
     CDS             82022..82618
                     /gene="recR"
                     /locus_tag="TU651_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL0896125.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            82766..83812
                     /locus_tag="TU651_000080"
     CDS             82766..83812
                     /locus_tag="TU651_000080"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL0896126.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        23629 a        15812 c        20144 g        24419 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctaagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcactcta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
    25981 tacttttaat cggtgtataa taagcgtaat atttttttat ttttactcat gattagaatg
    26041 gtaaaaaata aaggtgactt agtcgcgaaa atgatttaaa ggaggagcta tgaaaaaaag
    26101 ctttattcat caacaagagg aaatttcctt tgttaaaaat acatttacgc agtatttgat
    26161 tgctaagctt gatgttgttg aggtgcaagg tcctatttta agtagggtcg gagacggcat
    26221 gcaggacaat ttatctgggg ttgaaaatcc ggtatctgtc catgtcttga acattcctaa
    26281 tgcaaccttt gaggtggtgc attcgctagc aaaatggaag cgtcatacct tagcacgttt
    26341 tggctttaat gaaggtgaag gtcttgtggt gaatatgaaa gcgctccgtc ctgatgaaga
    26401 ttcgctagac cagacgcatt cagtgtatgt ggaccagtgg gattgggaga aggttatccc
    26461 tgatggtcag cgcaatctag cttacctcaa agaaactgtc gaaacgattt acaaggttat
    26521 ccgcttgaca gagctagctg ttgaggcacg ctatgatatt gaagctgtct tgccaaagaa
    26581 aattaccttc attcacaccg aggagcttgt tgccagatac cctgatttga caccaaagga
    26641 gcgtgaaaat gctatcacaa aagaatttga tgcggtattt ttgattggta ttggcggtgt
    26701 attgccagat ggcaagccac atgacggtcg tgcgccagac tatgatgact ggaccagtga
    26761 gtcagaaaat ggctaccatg gcttaaatgg tgatattctc gtttggaatg agtagctagg
    26821 cacagccttt gagctattct caatgggaat tcgtgttgat gaagaggctc taaagcgtca
    26881 ggtggacatt actggagatc aggaacgcct acaatttgat tggcacaaat cgctgctaaa
    26941 tggtctgttc cccctaacca tcggtggagg aattggtcaa tcgcgtatgg ccatgttttt
    27001 gcttcgtaaa aagcacattg gagaggtcca aacatcggtg tggccacaag aggttcgcga
    27061 tacctacgac aatattttat agatgatacg gaggctaggt ttttacctat agcctctatt
    27121 tttgtcccta agtgatgctt cattagagct catttagtgc taagcaggct cgtcagttat
    27181 ataataggtc aaaaatttga aaaaatgaat catttttaag gcttgacact agatttttgt
    27241 tataatatca gttatgagaa ttgtatcagg tgaatttgga gggcgtcccc taaaaacgct
    27301 cgaaggcaag actactcgac ccacatcaga taaggtacgt ggcgcgattt ttaatatgat
    27361 tggtccttat tttaagggcg gacgtgtctt agacttgttt gctggatcag gtggcctatc
    27421 aatagaggct atttctaggg gcatgtcaga ggcagtgctg gttgagcgtg atcgtaaggc
    27481 gcaagccatt atccaagcca atattaagat gacaaaagct agccagcaat ttacgctatt
    27541 aaaaatgaac gctgagcgtg cacttgatca cttatccggt cagtttgatg tggtgttttt
    27601 ggacccacct tatgctaagg aaacgatagt agccaatata gaggccttgg tggagaaaaa
    27661 tcttttaagc gacgatgtga tgattgtttg tgagacggat cggtcggtag ctctgccaga
    27721 ggcaattgcc tggctaggga tctggaaaga aaaacaatat ggaattagca aggtaacagt
    27781 atatgtcagg taagattgga ctttatacag ggtcatttga cccagtgaca aatggacaca
    27841 tggatatgat taagcgtgct agccatttgt ttgagcatgt ttatgtcggg atttttaaca
    27901 atccaaataa gcagagcttt tttacttttg agctgcgagc tcaaatgcta agcgaagcgg
    27961 tttgtgcctt gccaaatgtg acagtggttt ctgccgagca tggtcttgca gttgacctgg
    28021 ctagggagct gtctgtgacc caccttatcc gagggcttcg caatacagct gattttgact
    28081 atgagatagg cttagagtat tttaatcata gactagcccc tgatattgag accatttacc
    28141 tgatggcgac tcatgacctg cagcccgtta gctccagtcg tatcagagag ttgattgcat
    28201 ttagagcgcc aattactggt ttggttccgc aggctgttat taatcaagtg gagaaaatga
    28261 atgaaaacaa taaaaaaaat taaatggtgg ctgattggct ttgttgcctt gctttttcta
    28321 ctgttgacac tgtttttccc cttgccttat tatattgaaa tgccaggtgg agcctatgat
    28381 attcgctcgg tattgactgt caatggcaaa gaggataagg aaaagggagc ttatcagttt
    28441 gttgtagtga gcctcagtcg ggccaccttg gctaaattgc tctatgcttg gctaacgcct
    28501 ttcactgaga ttagcaccat ggaagatact actggtggct atagcgatgc tgactacctg
    28561 cgaattaatc gcttttatat ggaaacctct caaaacagcg ctgtttatca ggcccttact
    28621 ctagcaggca aggaggtaag ctttgattat aagggtgttt atgtcttaga cgtcagcaag
    28681 gattctagct ttaaaggtgt gctgcaccta gcagatacag tgacaggtgt caatggtaaa
    28741 acatttacaa cgtctgccga tctgattgat tatgtttctc atttgacctt gggagatgag
    28801 gtgcaggtac aatttacaac cgctggtgag tcaaagactg aaaaaggaaa gattattaag
    28861 cttaaaaacg gtaaaaatgg gattggcatt accctgacag accacacaca ggtcatttct
    28921 ggtgatgagg tcgactttag cactggaggt gtgggtggac caagtgcagg cttgatgttt
    28981 actcttgata tttatgatca aatcaatcac gaagacttgc gcaagggacg tgtgattgct
    29041 ggtacaggaa ccattggcaa ggatggaaaa gttggagata ttggcggggc gggcctaaag
    29101 gtggctgccg ccgccgctgc tggtgctgat attttctttg ttccaaataa tcctgtgcat
    29161 aaggacgtca aaaaagcaaa tcctaaggct attagcaatt acgaggaggc taaaaaagca
    29221 gctaaacgac taaagacagc aatgaaaatt attcctgtga aaaccgttca agatgctata
    29281 agctacctta aaaaatagaa gcaatgcgaa gcaggctaat agggcatgct ctgtcttgct
    29341 tctagttggt ggaatttagc tagctcaaag gtcttgagac ctaagcataa ggtctagaca
    29401 gtattctaga gctagacctt atgcttgatc ctgaacaagg aagaccgcca aagaagaaca
    29461 aaatcctcag gccaaaagag cccgtaggga aatattgcca ttatctatca aggctttttg
    29521 aagaaaatca cttaaagaca gtagggcgtt aggctttact gtcttagttt ttcttgcctg
    29581 aagtcatggc tgctgatgat gttacatcaa ggcttactag ccagcagagc acaaggagca
    29641 gctttggctt aggtttattt tctctgctga ctagtaaaga aggttgctgt cagtctgctt
    29701 acaaaaacct aaaaatagtg tataataggt aggctatggg ctgtcaggag tcgctagcct
    29761 gcttacccag accagccctt tgagaagagc aagcatggct cttctcagaa taacccagga
    29821 ttaacagaca tcaaaattaa tgctaaggaa aggagctata tgaaaagaga tattttacca
    29881 gagatgtata attacaataa atttcccggt ccggaattta ttcattttga tcattatgtc
    29941 aaggctgaag gcattgagtt attgctgctg aaaaatgaaa aaaatgcttt taacacaacg
    30001 agctttggtc agcgcttcac agagatatta ttaaagtatg actatattgt tggagattgg
    30061 ggcaatgaac agctgcgtct caagggcttt tacaaggatc atcatgatgt caaaaaagct
    30121 agtcgtattt ctcgcctaga agactatatt aaagaatttt gtaactttgg ctgtgcctat
    30181 tttgttttgg aaaaccctaa tcccaaggac atgccaaaag aggaggaaag gccatcaagg
    30241 cgcaggaaat cgtctaaagc caatcgccgc agaaatcagc ctcagcatag tcagcaggca
    30301 cctgctaaag acaacttcaa aaagctaacc aaggataggt cagcggacaa gccaagcttt
    30361 accagcaaaa agcgcccagc tcctaataag accaagggaa accaaaggcg ctctcgtact
    30421 agtcaactga accataaaac ggatcacttt atcatcagaa agaaggacaa ttaatctatg
    30481 aaaccatcaa tctatggcct aacgcgcgac gagctaattg cttgggcgat tgacaatggt
    30541 caaaaggcat tcagagcgac acagatttgg gactggcttt acagaaaacg ggttcaatcc
    30601 tttgatgaaa tgactaacat ttctaaggaa tttgttgcca ttctaaagga cagcttttgt
    30661 attaatccct tgaagcagcg tgttgctcag gaatcagctg atggaacggt taagtatttg
    30721 tttgaattgc cagatggtat gctgattgaa acggttttga tgcgtcagca ctatgggcag
    30781 tcggtctgtg taactacgca ggttggctgt aatataggct gcaccttctg cgctagtggc
    30841 ttgattaaaa agcaacggga tttaaacagt ggtgaaatca ctgcacaaat tatgatggtg
    30901 caaaactatt ttgataagcg tgctcaagac gaacgtgtca gccatgttgt tgtgatgggg
    30961 attggagagc cctttgataa ttatcaaaat gtgatgacct ttcttcggac gatcaatgat
    31021 gatcatgggc ttgctattgg tgctcgtcac attactgttt caacctcagg cttggctcac
    31081 aagattcgtg aatttgccaa tgaaggagtc caagttaatc tggctgtgtc actgcatgca
    31141 cctaataatg agctgcgctc aagtatcatg aggatcaatc gttccttccc acttgataag
    31201 ctcttttcag caatcgaata ttacattgaa acaactaatc gtcgtgtgac ctttgagtat
    31261 atcatgctta ataaggttaa tgatggggta gagcaggcac aggaattggc agatttgacc
    31321 aaaaggattc gcaagctgtc ttatgttaac ctgattccct ataatcctgt ctcagagcat
    31381 gaccaataca gtagaagtcc taaggagcgt gtggcagcct tttatgacat tctaaagaaa
    31441 aatggagtga actgtgtcgt tcgtcaggag catggtacag atattgatgc tgcctgcggt
    31501 cagctgcgct ctaataccat gaaaaaggac cgacaaaaag cagcagctgc aaggacatga
    31561 tgacttggtc aaggttgctg atttgattga taggagatgg agataaaaat ctgacctcaa
    31621 ataaagcaaa caaataggtc tagttttctg agatcccgaa agcaggtctt gttcgttttt
    31681 taatgaatga gactaggtca taaagtacat gcgttaagaa tgtctaaagt gcagctcttt
    31741 ttgtcccagc ctccctcttt tatcttggta gcagttgtca agtaattgct aagcaacagt
    31801 gttttatctt tattggctgt aaaaaaagat atagtgcctt tattcacacc ttttctgaat
    31861 cacttgagcc ttgttctgac cgctcctttt ggtgcttctg atccatatag cctaagcttt
    31921 tcagagctat gaatcgaggc aaaataatag gtgttagccc tagctgcttg atgtagctag
    31981 ggcttttgtg acctagctgc cagtgagcct ttcaaatagc aatatggcta taaggcccag
    32041 tgtcagatag ggaataaaag ggattttctt agtttgtaga agtaggcagg ctagaattcc
    32101 gatcagactg gcaatttgga cgatccataa caaagagcta agcttgacca caagagcaag
    32161 attagctagg taaagaaaat ctccggcacc aatattgata ggaaaagcta cgcttagcag
    32221 tgcaagcaaa agcaatagca ctgttaacag gttaatgcta taaaatggca gcagaaacaa
    32281 aaagctcatc agccagatga gcaaaggata ctcttgactg tctaaatcaa aaaagcacag
    32341 tagcaaagag aagcatagga gataaagctg tgtccaggtc aagccgcaaa gggcagccag
    32401 tccgaaaatg aggctggtga ttatttctaa ataaggaagc ataacccagt gcttttgttc
    32461 atgcttagag ttgtaagtgg gctttgccat aggaaaaaag aggcttgaaa gatgaagttg
    32521 acctatatag agcttgaccc aagcctttgc ttgctgttca gaaaacaggt taagtattag
    32581 ccgaaagagg tttcccacaa gaaaaccaca atagcaataa aaaatagtgt tcatacttat
    32641 ttatccgaaa aacaatttaa attcttgcaa tattttaaaa aacggtgtac aatgaaacta
    32701 taaaacgaga atgattctaa ataagctgtt gatacttatc tgaattggct cgttatcgtc
    32761 gaatggagct gacaagagag tgacttttct tgctgcatac cattcatgcc cttttatatc
    32821 tatcagtaag gagagtttat tatgacaaac acactcgttg aaaacattta tgcatcagta
    32881 actcataata tttctaaaaa agaagcatca aaaaatgaaa aaaccaaggc tgttttaaat
    32941 caagcagtag cagatctatc tgtagcagct tcaattgttc atcaggttca ttggtacatg
    33001 cgtggtcctg gctttttata cctgcaccct aagatggatg agctattaga ccgcttgaac
    33061 gcgaacctag atgagatgag tgagcgcttg attactattg gtggggcacc ctactcaacc
    33121 ctagaggagt tttcacagca ttctaagcta gatgaaacaa agggaagcta tgataagtca
    33181 gtagctcagc atttagctcg tttggtagag gtttaccttt accttaccag tctttatcag
    33241 gttggtttag acattactga tgaagagggt gatgctgctt caaatgattt gttcacagca
    33301 gcaaaggctg acgctgaaaa gactatttgg atgctacagg cagagcgtgg tcaaggtcct
    33361 gctattttct aaagcgtcat acaactgata taacataaaa aaggcagagc gtggtatagc
    33421 cctgtctttt taacgccttt aaagtcagct attagtgcta gtgatgtcag gtctcacagc
    33481 ttttttatga tggatgacca acatttttag accttgtcac cacagcagag catgtggcat
    33541 ttagtccacc ttgggctcac gtcgatggtc ttacttatga tatatcaagg cttgtgacat
    33601 taccgttgcc ttttatcttc agtctgagct gctggttcct actgctgatg ctgcttgata
    33661 gtgttatagt gattttcaga aatatggaaa gcgattgcat aattgtcttg aaatctcatg
    33721 cgtaatttgc taaaatctag ttatatgaaa acattatacg atgtacagca gctgttaaaa
    33781 ggctttggta ttgttatcta catgggaaag cggctttatg atattgaaat gatgaaaata
    33841 gagctgcaaa ggctatatga tggtggcttg ttggataaac aggcttattt aactgctgag
    33901 ctgattttac gacgtgagca tcgattagag ctaaaaagag aagggcaaga aaatgagtca
    33961 aaaattgata gggattgatt tgggcggaac cacgattaaa tttggtattt taacctcaga
    34021 gggtgacgtt caggaaaaat gggcgattga gacaaatgtt ttagaggacg gtaaacatat
    34081 cgttccagat attgtcgcct cactcaagca tcgccttgac ctttatggac tgactaagga
    34141 cgattttatc ggtattggta tgggctcacc tggagctgtc aatcgcacag atcatactgt
    34201 tacaggggcc tttaacctca actggagagg cacccaagag gtgggatctg ttattgaaag
    34261 ggagctagga attccctttg ctattgataa tgacgcaaat gttgcggccc tcggcgagcg
    34321 ctgggtcggt gcaggtgaca ataatcctga tgtggtcttt atgaccttag gaacaggtgt
    34381 tggtggtggt atcatcgctg atgggaactt gattcatggt gtggctggag ctggtggtga
    34441 gattgggcac atgatagtag agccgcttaa gggctttgct tgcacctgtg gctcacaggg
    34501 ctgcctggag acagtggcct ctgctacagg tgttgttaag gttgctcgtc ttttagcaga
    34561 agcctacgaa ggagattcaa gcattaaggc agcgattgat aatggagagg ctgtctcaag
    34621 caaggacatt tttgttgcag cggaggctgg tgatgccttt gccaactctg ttgttgaaaa
    34681 ggtcagttat tatctaggac tggcagcggc taatatctca aatattttga accctgattc
    34741 ggtcgttatt ggcggtggtg tatctgctgc gggtgagttt ttacgttcac gtgttgaaaa
    34801 gtactttatg acctttacct ttccgcaggt tagacagtcc actaaaatca aaatagcaga
    34861 gcttggtaat gatgctggta ttattggtgc agctagcctt gcaagacaat ttatcacaga
    34921 ataggagtta atgatgtcac cacttacaat gattggctgg gtattgcttg cgggagtgat
    34981 tgcctattac ctttggaatt atgtttccta tagaagaatg gcaaagcagg ttgataatga
    35041 tacctttaag gagctgatgc gtcaggggca agtgattgac ctgcgcgatc cagcttcctt
    35101 tagggcaagg catatcctag gcgctagaaa ttttcctgcc cagcagttta ctacctctat
    35161 taaggctttg agaaaggaca agccaatctt gctttatgaa aatgtaagac ctcaatatcg
    35221 ggtcaaagca gtcaaaacat tacgtaaggc tggctatacg gacctttatg tcctaaaagc
    35281 gggactagat tattggaatg gtaaggttaa atagccttat agtccttttt gctgagctaa
    35341 cgtttgctgc tatgtgtcgg aacgttgcaa gcagcagctt atctaagctt gtcatgctag
    35401 tttcacagcc caaagtggct ggccgtataa acgcagctgc ttttagatgc cggtaggagc
    35461 ttttgtcagc ttctttaggg attgttttaa gtgatgtaga gaggccgttc tgagagaaag
    35521 ccttgtagtt agaaaaagag atgagaaagc taaggctctt gctgctgttg taagagttag
    35581 ctttcttttt cttttttgtg tggcgcattt aagggcttga aaacatttac aattccctca
    35641 gatcggtttt ttaaaaaaat ttgtgttata ctgttttagt taaaactatt tatgctacaa
    35701 gaggaaaaaa tgacaaaatt tagagaagat attcgtaacg ttgctattat tgcccacgtt
    35761 gaccatggga aaacaacgct cgttgatgaa ttactaaagc aatcccatac actagatgag
    35821 cgcaaagagc ttcaagaacg tgcgatggat tcaaatgacc ttgaaaaaga gcgtggtatt
    35881 accattcttg ctaaaaatac cgcagtagct tataacgatg ttcgtattaa tatcatggat
    35941 actcctgggc acgctgactt tggaggcgag gttgagcgta tcatgaaaat ggttgatggt
    36001 gttgtccttg ttgttgacgc ttacgaggga accatgcctc aaacacgctt tgtgctgaag
    36061 aaggccttag aacaaaattt aaccccaatc gttgtggtta ataagattga taagccatca
    36121 gctcgtccag ctgaggttgt tgatgaggtt cttgagcttt tcattgagct tggtgcagac
    36181 gatgatcagc tggagttccc tgttgtttac gcttcggcga tcaatggcac atcttcgttg
    36241 tcagatgatc ctgctgatca ggaaaaaaca atggctccga tttttgatac cattatcgat
    36301 catattccag cacctgttga taactcagct gagccccttc aattccaggt gtcacttctt
    36361 gattacaatg attttgtagg tcgtattggg atcggtcgtg tctttcgtgg gactgttaag
    36421 gttggagatc aggtgacgct ttcaaagctt gatggcacca ctaaaaattt ccgcgttact
    36481 aagctgtttg gcttcttcgg gcttgagcgc aaggagattc aagaggccaa ggctggtgac
    36541 ttgattgcag tttctggtat ggaggacatt ttcgttggtg agacgattac accaacggat
    36601 tgtgtggagg ctttgcctgt tcttcgcatt gatgagccga cacttcaaat gaccttcttg
    36661 gttaacaact ctccctttgc tggtcgtgaa ggcaaatggg taacctctcg taaggttgag
    36721 gagcgtttgc ttgtggagct tcaaacagat gtgtcccttc gtgttgagcc aacagaatca
    36781 ccagataaat ggattgtgtc aggtcgtggt gagctgcatc tatctatttt aattgagacc
    36841 atgcgtcgtg agggctatga gcttcaggta tcgcgtccag aggttatcat taaggaaatt
    36901 gatggtgtca agtgtgagcc ttttgaacgt gtacagattg acacaccaga ggaatatcaa
    36961 ggtgctatta tccaatcctt gtcagaacgt aagggggata tgcttgatat gcagatggtt
    37021 ggtaatggtc aaacgcgtct tatttttctc attcctgccc gcggcttgat tggttattcg
    37081 actgaatttt tatcaatgac acgtggctat ggtatcatga atcatacctt tgatcagtat
    37141 ctgccagtgg ttgctggtga gattggtgga cgccatcgtg gagcgctggt ttcgattgaa
    37201 aacggtaagg caacaaccta ctcaatcatg cgtattgaag agcgcggaac aatctttgtt
    37261 aacccaggaa ctgaggttta tgagggcatg attgttggtg aaaattctcg tgacaatgac
    37321 cttggggtta atatcacaac tgctaagcag atgaccaacg ttcgttcagc aacaaaggat
    37381 cagacagctg ttatcaaaac accacgtatt ctaacccttg aggaatctct tgaattcttg
    37441 aatgatgacg aatacatgga ggtaacgcca gaatcaatcc gcttgcgcaa gcaaattttg
    37501 aacaaagcag cgcgtgataa agctaataaa aagaaaaaat cagcagaata aaggctggtt
    37561 ggtctgagca tcacactccc ttgccgcttt aactagtaag ctaggttggc agaggattga
    37621 aaggagcttt ctgtgtttta tcttattatt gcagccttga ttacctctta ttacctgttt
    37681 atggcaccaa agagcgtccg taacacacta ggtatgattg gtttggttgg tttggttgcc
    37741 ctattgattg tgctagctgg cttaagtttt atcaaaatca tgcaaacgcc caaggaaatt
    37801 ttcgttggtc tagccatgat agtattgggc tactatgccc taagggacat tcaaaaaatc
    37861 cctaaaaaac caaagagtaa acattagcat caagcattga gtcaaatctt aatagggttt
    37921 gactttttct gtctttgtac tggccttatg cgctgctatc tgtaaaatct tgaaaaagca
    37981 gttaaataag ggtaaaatag tagtcaaata gacatagata gtgtggataa aaatgaagac
    38041 aataacggaa ttccaaaata aaaaggtatt gattcttggc ctggccaaat cgggcgaagc
    38101 agcagctagg cttttagccc ggttgggagc tattgtgaca gttaatgata gcaagccctt
    38161 tgaggaaaat cccgcagcac aggctcttct tgaggagggc ataagggtta tttgtggtag
    38221 ccaccccttg gagctgttag atgaagactt ttattgtatg gttaaaaacc cagggattcg
    38281 ctatgacaac ccgatggtgg tacgcgcctt agataaggct atttctattc taacagaggt
    38341 tgagctggct tatttggtat ctgaagcacc tatcattggt attacgggct caaatggtaa
    38401 aaccactaca accacaatga ttgctgatgt gctaaatgct gggaaccatt cagctctttt
    38461 ggctgggaat atcggctttc ctgcttcaga ggtggctcaa gctgctacag caaaggatat
    38521 actggtcatg gaattgtctt cctttcagct gctggggact gagcagtttc agccacatat
    38581 tgcagtcatt actaacctag tgcctactca tcttgattat catgggagtt ttgaggacta
    38641 tatagcggcc aagtggcgca ttcaacatcg aatgaccgat aaggattacc ttgtgttaaa
    38701 tgctgatcaa gagctggtaa aatcattggc tcaaaagact aaagcaagtc ctgtcttttt
    38761 ttctaccaaa gaaaaagttg atggtgctta tttggcagat gggtatcttt atttcaaaga
    38821 ggagaggctg atgtcagcag ctgagcttgg tgttcctgga aggcataaca ttgaaaatgc
    38881 tcttgccacc attgctgttg caaagctaag aggcatttct aatcaagtga tatcaaggac
    38941 tttgtctcac tttagggggg tgaagcaccg ccttcagtta gttggtacat tgaatcaagt
    39001 gaccttctac aatgacagca agtcaaccaa tatcttggct tgtcaaaaag ccttgtcggg
    39061 ctttgataat agcaaggtta tcctgattgc tggtggcttg gatcgtggca atgaatttga
    39121 tgagctggtg ccagacctcg ttggtcttaa aaagatgatt cttttagggg aatccgcaga
    39181 gcgtatgaag cgagctgcag acaaggcagg agtgtcctat cttgatgcca aagatgttgc
    39241 agctgccact aaaatagcct ttgagcaggc aaaggctggt gatattatct tgctgagccc
    39301 agccaatgct agctgggata tgtatccaag ctttgaaagc cgcggcgacg agtttttagc
    39361 agcctatgac gcgttaaaag gagaggctca atgaccaaga aaatcatttt taccggtggt
    39421 ggaacagctg gtcatgtcac tttaaacctt atcctcatac cgaagtttat caaagatggc
    39481 tgggaggttc actatattgg tgatgacaaa ggcattgagc atcaggagat caaaaagtca
    39541 ggtcttgatg tcacctttca tgctattgca actggaaaat taaggcgtta tttctcttgg
    39601 caaaacctgc ttgatatctt caaggtaggc tttggtgtca tgcaatcact ttttatcata
    39661 gctagactaa ggcctaaggc tctcttttca aagggaggct ttgtgtcggt tcctcctgtg
    39721 attgctgcaa ggcttttagg ggtgccggcc tttattcatg agtcggatct ttctatgggc
    39781 ttggctaata ggattgctta tcggtttgca acaacgatgt atacaacctt tgagcaagag
    39841 cagacactgg caaagctcaa gcatgttgga gcggttacca aggtgacagg tcctgggagt
    39901 cgatcggtga cttctaagca gcttgaagct gttttggagt attttgatcc taatttaaaa
    39961 acacttttgt ttattggagg ctccgcaggg gctagggtgt ttaaccgctt tatcactgac
    40021 catcctgagc taaaggaaga ctttaatatc atcaatatct ctggcgatcc tagcctaaat
    40081 gagcttagtt ggcatcttta ccgcgtggat tatgtgactg atctgtatca accgctcatg
    40141 gaaatggctg atctggtagt gactcgcgga ggctctaaca cactttttga attattagcg
    40201 atgagaaagc tccagcttat tatcccactt ggcaaagagg ccagtcgagg tgatcagctt
    40261 gagaatgctc attattttac aacaaggggc tatgctgagc aattattgga gcaggaattg
    40321 accctgcctc attttcaaga gaaagtgaga gaagtctttg ctaagcaatc ggactattta
    40381 tctgcaatga agagctctag cgagctccaa tcaccagaaa gcttttacca gcttttaagt
    40441 gccgacatta gctccgcgac aaaggaaaat taaatggcag ataagacaaa acattcagaa
    40501 gaaaaagccg ctttgaccga atggcaaaag cgtaatattg aatttctcaa caagaagcag
    40561 cagcaggctg agaaagacaa aaaactaaaa gaaaaattat taaatgagaa aatagcgcaa
    40621 gctcagggag aggcagcttc aaaggctgac caagaagata cagatgaagc tgaggagaaa
    40681 actgaggtaa gccaagcggg tactgatgag ggtgagccgc tgccagaagc atcagagcag
    40741 gaagtcccct ccccaaaaga caagccatta aaagtcccca aagaaaaaag tccaaagcag
    40801 caggcacttc aaaagggctg gcctgtattg ctggtgtcgt ttgtggtttt gtgcctgtcg
    40861 atttttatga tcacacccta tagtaaggtc aaggatttct ccgtcaaggg caataaaaaa
    40921 acaagcgttg aggacttagt tagagacagt gggatcaagt catctgatta ctggattact
    40981 ctattagcct ctccgggttc ttatgaaaat gcggttttaa aagccaatcc ctgggtgaaa
    41041 aaggtggctt tgcgttacgg ctttcccaat catttccgct ttgatgtgac agagtttgat
    41101 attattgcct acgctcaggt agctgaaggg tttcaactga tcctagaaaa tggcaagcga
    41161 gttgctgctg tcaagcaggc tgctttgcct aaatcctttt tgattttaaa tcttgagcat
    41221 gaaaaagaga ttcaagatgt cattaatcgc ttgaccaaaa tcccaagtga cctagtcaag
    41281 gctatcaaat cagtgtcatc ggccaattca cagacaacta aggatttgct gcttcttgaa
    41341 atgcacgatg gcaaccttat cagggtacct cggtcacagc ttgagctaaa gctgccttat
    41401 taccaaaaaa tcaagaagaa tcttgatact gctagcattg ttgatatgga ggttggtatc
    41461 tatacgacca ctgctgaaat tgaaaacatg cctgaggtgc cagcgtctgc tcaagcttct
    41521 caggcagata agcctgctga ggcttcacca gagcagggtg aagagcaggc cacacaggag
    41581 cagcctagcc ctgaaacacc tgctaatcct gaggccacaa atccctcagt cgcccagcct
    41641 actgagcagg caaatcaaca gtaatcgttt agggtaagag aagggggcaa aaaagcattt
    41701 aaggctctta aattaggccc ttgttgaacg gcaaaaaaac attaagttta tataacaaaa
    41761 aacgtaaaat ggtaacattt tacgtttttt tatgatataa tattccctga ataattctgc
    41821 tttttagcag tgtttttgaa tagtaaaagt ttggaaagta agtgaggtcg agtgaatggc
    41881 tagaaatggc ttttttactg gtttggacat tggaacaagc tcgataaagg ttttggtagc
    41941 agagtttatc tctggcgaga tgaatgttat tggtgtgagc aatgttccga gtactggcgt
    42001 aaaagatggc ataatcattg atatagaggc agcagccgct gctattaaaa ctgcagtaga
    42061 acaagctgaa gaaaaagcag gaatgacaat tgaaagggtc aatgttgggc tgccagcaaa
    42121 cctccttcaa attgagccga cacaaggcat gattcctgtt cctagcgaat caaaagaaat
    42181 caaagatgaa gacgttgata gcgttgttaa gtcagcacta actaagagca ttactccaga
    42241 gcgagaggtg atttccttag tccctgaaga gtttattgta gacggctttc agggcattcg
    42301 agatcctcgt ggcatgatgg ggatcaggct tgaaatgcgc ggtctgattt acactggacc
    42361 aagcacaatc ctgcataact taagaaagac agttgagcgt gctgggatta aggttgaaaa
    42421 catcatcatt tctcctttgg caatggctaa ggcggtgtta aatgaaggtg aacgtgaatt
    42481 tggtgctacg gtcattgaca tgggtggagg acaaaccacc gttgcctcaa tgcgagcaca
    42541 ggaattgcag tacaccaata tctatgcaga gggtggcgag tatatcacaa aggatatctc
    42601 taaggttctt aaaacgtcaa tgtcaattgc agaggccttg aagtacaatt ttgggcaggc
    42661 tgatatggca gaggcaagct tgactgacac tgttaaggtt gatgttgttg gcagtgatga
    42721 gccagttgag gtaacagagc gttacttatc agagattatc tcggctcgtg ttcgccatat
    42781 tctagatcgt gttaagcagg atttagaaag aggacgcctg cttgatttac ctggtggcat
    42841 tgtgctgata ggtggcggcg ccattatgcc gggcgtggtt gaggttgctc aagagatttt
    42901 tggaaccaat gttaagcttc atattccaaa tcaggttggt attcgtaacc caatgtttgc
    42961 caatgtcatt agcttggtcg agtacgttgg tatgatgtca gaggtggacg ttttagcgca
    43021 aaatgctgta tcaggcgagg aattgctaag acgtaagccg atcgacttta ctggccaaga
    43081 agcttacttg ccagactaca atgagactag gggatttgaa ccggctccta attatgagca
    43141 gcaagtgccc caagcagact acgagcctca agaacccgct gaaccaaagc aaaagatttc
    43201 agagcgtgtt cgtggcattt ttggaagtat gtttgattaa aagtaataaa gtgaggaaat
    43261 aaaatggcat tttcatttga tacggcatcc attcaaggtg caatcattaa ggtaatcggt
    43321 gttggtggag gtggcggaaa cgctattaac cgcatgattg atgagggggt tgcaggtgtt
    43381 gagtttatcg ctgcaaacac tgatattcag gcattaagct catcaaaagc agaaacagtt
    43441 gttcagcttg gtcctaaatt aactcgtggt cttggtgctg gaggtcagcc agaggttggt
    43501 cgtaaggcag cagaggaaag cgaagaggtt ctcacagaag ctttgactgg cgctgatatg
    43561 gtctttatca ctgctggtat gggtggaggc tctggaacag gagcagctcc agtgattgct
    43621 cgtatcgcta agagcctagg agccttgact gtggcagttg taacacgtcc atttggcttt
    43681 gaaggcaaca aacgcagtaa ttttgccatt gaggggattc aggagctaag agagcaggtt
    43741 gataccttat tgatcatctc aaataataac ctgcttgaaa ttgttgacaa aaagacacca
    43801 ttgcttgaag cgcttagcga agcagacaat gttttgcgtc agggtgtaca agggattact
    43861 gatctgatta caagccctgg cttgattaat cttgactttg ccgatgttaa gactgtgatg
    43921 gcaaataaag gcaatgcact tatggggatc ggtattggtt ctggtgagga acgtattgta
    43981 gaggcagctc gtaaggctat ctactcacca ttacttgaaa caacaattga cggtgctgaa
    44041 gatgttatcg ttaacgtgac aggtggactt gatatgaccc tcacagaggc tgaggaggca
    44101 tctgaaattg ttggtcaggc agcaggtcaa ggcgttaaca tctggctagg aacatcgatt
    44161 gatgactcta tgagagacga aattcgcgta acagttgttg caacaggtgt tcgtcaggat
    44221 aaggcggagc aagcctcagg atttcgtcag ccacgcacct acactcagtc taacgctcag
    44281 caggctgctg gagcacaata tgcttcagag caggtgagac agactgcgca gccaagcttt
    44341 gatcgtcgtt catcaagctt tgattttgat atgggtgaaa cacgtgagat gcctaagtct
    44401 cagcaagcta tgccagctca tggccacaat cataatcagg gctcagcttt tggaaattgg
    44461 gacttacgtc gagacaatat tgctcgtcca gcagaaggtg agcttgacaa tcaattgaac
    44521 atgtcaacct tctcatcaaa tgatgacatt gatgatgaat tagaaacacc accatttttc
    44581 aaaaatcgtt aatgatggat ttacaaaaaa ataaggatat tgtttttgaa aatattcgct
    44641 tagccactca ggcagccaac cggcctgaaa acagtgtgtc agttatcgct gtcacaaaat
    44701 atgtggacaa ggcagttgca ggtcagctga ttgatatggg gattgagcat atcgctgaga
    44761 accgtattga taagtttcta gataaatatg aagccttgaa agataggcaa gttacttggc
    44821 attttatcgg tactttacag cgtcgaaagg taaaggaagt gattaataag gttgattatt
    44881 ttcatgcctt agattcagta aaactggctt tagaaattga aaagagagct gaccaccctg
    44941 tgaagtgttt tctacaagtt aatatttctg aagaagaaag caagcatggt tttaagattg
    45001 ctgagcttga tgctgctatt gaggaaatca gcaagatgga aaagcttcat cttgtcggta
    45061 tcatgacaat ggcacctatt gatgccagtc agcaagagct tagaagcatt ttccaaaaag
    45121 caaatcaatt aagaaaaaac ttgcagtcaa aaaagagaaa gaatatgccg tttacagaat
    45181 tgagtatggg catgagtaac gattatccaa ttgctattca agaaggctca acctttgttc
    45241 gtattggaac atctttcttt cactaaatgg agaataagat ggcaattaaa gacgcattta
    45301 ataagatgat ttcttatttt gatactgatg gggtcagtga agtagaagag gagctatcct
    45361 ctaaaaagca agaagagcct gtgactaaat cacaacagac cagcagacct aatcagcagc
    45421 aacaagcagc tagagcgagt cagccccagc agcctaagca ggctagacct cagatgcaag
    45481 ctcagcaaag accacaatca caatcaagag ctgcctatgc tgagcgacca tatcaaggtc
    45541 aaagtcaagc acgtgtttct catgactaca atgacagaag ggcgacgtca gccccgtctg
    45601 cttctagtcg tcgtgagcaa tatcagcatg ctgctcatca agagcaaaca actattgcct
    45661 tgaagtatcc tcgtaagtat gaggacgccc aagaaattgt tgatcttttg attgttaatg
    45721 agtgtgtgct gatcgatttt caatacatgc tagatgctca ggcaaggcgt tgcctagatt
    45781 ttattgacgg tgctagtaag gtattgtatg gtactctgca aagggttggt tcttccatgt
    45841 atctgttgac cccatcaaat gtatctgtta atattgaaga gatgaatatc ccaaataatg
    45901 gccaagatat tggttttgat tttgatatga agagacgcta gtgtgatgat ttttatactg
    45961 ttgatacttc taaagctaat taaggtttat tcctatttgc tgctagtcta tgccttactg
    46021 tcttggtttc ctggagccta cgactcttgg cttggcaggc tggtcagcga tatagtagag
    46081 cctatcttaa aaccctttag atcattgaac ctacagtttg cgggcttgga ctttactatt
    46141 tacctagtga tgattggtct aaatgtttta agtgagatct tgataagagt gttgatctca
    46201 tgactgttca aacaatgctt tatcagcatt ttcagcctga tgaacaccca tttattgaaa
    46261 gaatgcttga cttgatcgct cgtgttgagg ctaattattt attagaggtt actgattttt
    46321 taaatccgcg agaggtcacg attttaaaag gcttagtcgc agcaaccaat ctgcagtgct
    46381 ttagctctac tgattattat cctagtgaat atggtcgtgt gattgttgct cctgactatt
    46441 attgtctaga taaggcagat tttgacttgg ctttgattga ggtgacctat aatgctaagt
    46501 ttaatcagct gacacatgca cagattttag gcaccttaat taatgaattg ggaatcaaaa
    46561 gagccttact tggcgatatt tttgttgaga taggtcatgc tcaggtcatg attaatcgac
    46621 agctgttaag ctattgttta ggaacgattg ctaaaatagc aaaagctagg gtcaagctca
    46681 aagaaattga tcttgatcag ctgttaaatc tgacagctaa tcagcaggtt ctgactgata
    46741 taatggtatc tagtctacgc gttgatcgct tgattgctac cgtattaaag caatctagaa
    46801 atcaggcgat aaggcttgtt gaagcaggca aggtcaaggt taactatcag cttgtcacta
    46861 aagcctctca gcctgtagct gttggtgatt taatcagcat tcgtggctac ggtaggttta
    46921 gcatactaac agacaatggc ttcacaaaaa atgggaaata taagctaaca cttagcaaaa
    46981 tgatgcgtaa ataaggagat ataatggcac ttacagcact agaaattaaa gataaaacgt
    47041 ttaagacaaa gtttcgtggc tacagtgaag aggaagtaaa tgaatttctt gagattgttg
    47101 tagacgatta tgaggctttg gttcgcaaaa atcgtgataa tgaagctaag ataagagagc
    47161 ttgaagaaaa gctgtcttac tttgatgaga tgaaggaatc attgagtcaa tctgttatcc
    47221 tagcccagga aacagctgaa aaagtgaaat cctcagcaaa tgctgaagca accaatttgg
    47281 tcagcaaggc aacctatgat gctcagcatt tacttgatga gtcaaaagca aaggctaacc
    47341 aactgttgcg cgacgcaaca gatgaagcaa agcgcgttgc tattgagaca gaggaattaa
    47401 agcgccagac acgcgttttc catcagcgct tggtttcagc tattgagtca cagctaagct
    47461 tatccaattc gcctgagtgg gacgaattgt tgcagccaac agctgtctac cttcaaaact
    47521 ctgatgcagc ctttaaagag gtggttaaaa ctgtccttaa tgaagatatt cctgaggctg
    47581 atgacagcaa ttcctttgat gcaacacgtc agtttacacc agaggagcta gaggagctgc
    47641 agcgtcgtgt tgaagaaagc aataaggagc tagaagccta tcaggtgcag cgagaagagc
    47701 aagctagcga gcctgaagtg aacctaagcg agacacagac ctttaaattg aatatttaat
    47761 cataagaaaa acaggattga atgcccaaaa tcacagcaag taggagatga tgagagtcct
    47821 atattccctg agcatgacaa ttatcatttt cttcaatcat cactgaatga cagtaagtga
    47881 cgagggaggc tcaccttacg agcaaagagg gaacagcaaa agggatttta ctgttctgaa
    47941 ttaaggtggt accacgagct ttcgtccttt ttgagacggg gctttttttg taattctgat
    48001 aagatattga ctaaaaggag tttgacaaga tgaaattaaa agaaacactt aacttaggca
    48061 aaacggcctt tccaatgcgt gccggtctac ccaacaagga gccacaatgg caaaaggctt
    48121 gggacgaggc tgagatttac aaaaaacgtc aagccttaaa tgaaggcaag cctgcctttc
    48181 acctgcacga tgggcctccc tatgcaaatg gtaatatcca tgtcggacat gcgctgaata
    48241 aaatttcaaa agacattatt gtacgtgcca aatctatgtc aggctatcaa gcgccttttg
    48301 ttccaggttg ggatactcat ggccttccta ttgagcaggt cttggctaag cagggggtta
    48361 agcgtaaaga gatggatctg gctgactatc ttgacatgtg tcgtcagtac gcgttaagtc
    48421 aggttgataa gcaaagagac gactttaagc gtctcggtgt atctgctgat tgggacaatc
    48481 cttatgttac cttagatcca agctttgaag ccgatcaaat tcgtgtcttt ggtgcgatgg
    48541 ctgataaggg ctacatttat cgtggggcaa agcctgtgta ttggtcatgg tcctctgaat
    48601 ctgctcttgc tgaggcagaa atcgaatacc atgatattga ttctacatcg ctttactatg
    48661 ctaatagggt taaagatggt aagggaatcc ttgatactga cacctatgtt gtggtttgga
    48721 cgaccacacc atttacggta acagcttctc gtggtctaac agttggacct gatatggatt
    48781 atgtggttgt tagacctgca ggttcagacc gtaactatgt ggtggcagaa ggactgctag
    48841 acagtctggc tgctaagttt gcttgggaat catttgagat tttggccaat cataagggct
    48901 ctgacttgga atacattgta accgagcacc cttgggacag tgaggttgat gagctagtca
    48961 ttcttggcga tcatgtgacg ctagattcag gtacaggtat cgttcataca gcacctggct
    49021 ttggtgaaga tgactacaac gttggtatga catatggact tgaggttgca gttacagttg
    49081 atgagcgtgg tttgatgatg gaaaatgcag gtcctgattt tcatggtcaa ttttatggca
    49141 aggtaactcc gattgttatt gaaaagcttg gagacctatt gcttgctcaa gaagtgatca
    49201 accactccta tccatttgat tggcgcacga aaaaaccaat tatttggcgg gctgttcctc
    49261 agtggtttgc ttctgtgtct gacttccgtc aagagattct agatgagatt gacaaaacaa
    49321 cattccaccc gacatgggga aagacacgac tctacaatat gattcgtgat cgtggcgatt
    49381 gggtgatctc tcgtcagcgt gcttggggtg ttccactgcc tattttctat gcagaggacg
    49441 gcacagccat tatgactaag gaggtaactg atcacgtcgc agatctgttc caagagcatg
    49501 ggtccattat ttggtggcaa aaagaggcta aggagctttt acctgaaggc ttcacacacc
    49561 caggctctcc aaatggggta tttaccaaag agacagatat catggacgtc tggtttgatt
    49621 cagggtcttc ttggaatggt gtgatgaatg ctcgtgatca tcttgcttat ccagctgacc
    49681 tctaccttga gggctccgat caatatcgtg gttggttcaa ctcatcactg attacctcag
    49741 ttgcggttaa tggtcatgca ccgtataagg ctatcctatc acagggcttt gtccttgatg
    49801 gtaagggtga aaaaatgtct aaatctaaag gaaatatcat ttcacctaat gatgttgcaa
    49861 agcaatatgg tgctgatatt ctccgtctct gggtagcttc tgttgataca gataatgatg
    49921 tgcgtgtgtc aatggatatc ctaggacagg tctctgaaac ctatcgtaaa atccgtaaca
    49981 cgcttcgctt cttgcttgct aatacatcag acttcaatcc acatacagat aaggtggctt
    50041 atgctgagct tgctgctgtt gataagtaca tgaccatcaa gtttaacaag ctagtaggag
    50101 ctatcaatac tgcctatgag cgttatgact tcatgacgat ttacaaggct gtggttaact
    50161 ttgtgacggt tgacttatct gctttctacc ttgattttgc caaagatgtg gtctacattg
    50221 aggctgctaa cagcctggca cgtcgtcgta tgcagactgt cttttatgat attttggtta
    50281 atatcactaa gctattgact ccgatccttc cacatacggc agaggaaatc tggtcatatt
    50341 tagagcatga gccagaagac tttgtacagc tatcagagct gccacaggct cagacttttg
    50401 ataatcaaga tactatccta gaggaatggg aagcctttat gacgcttcgg gcacaggcgc
    50461 aaaaggcttt ggaggaagca cgtcatgaca agattattgg taagtcctta gaagctcatc
    50521 tgacaattta tgcaagtcca gaggttaaga cactgttgac agctctagat agcgatattg
    50581 cactgctatt gattgtctct cagctaacca ttagtgagga gccagctcct gagaatgctg
    50641 tcagctttga tgatgttgcc tttacggtag ctcgtgcgca aggagaggtt tgtgagcgtt
    50701 cacgtcgtat cgatccaacg accagaatgc ggtcttataa tgcctttgtt tgtgaccaca
    50761 gtgcgaaaat tatcgaagaa aacttcccag aagcagtagc agaaggcttt gactcagctg
    50821 ctaattaagc aactaacagc tctgttcccg agttaaataa gcattggcgt gcttttgcca
    50881 atccagcagc aaggtgctag tcggtctggg cgtacctgcc ttactaggga ctctttgtgt
    50941 gggagctgat aagtgacctg ccttgagctt ggcaggtcta ggcttcttta taggttcacg
    51001 atttacgatt gactgggctt agagaagggc tagtcctgct aggcggcatt ggatatgaac
    51061 tgagtagtca tcatagctat aaaaaaacaa gcgcagactc acgtcagctt aatcgtgagc
    51121 ggcgcttgtt ttttcttggt tggggggtga aggcgaggag ctattaaagc taatattaag
    51181 cgatcaaaaa agcctagacc actagtcatg ttgtctaagc ttcagctgtt agagaggagc
    51241 tttctgagtg gaaggtagcc tatgctgata ggtgctgcct tagcctttta gcagtagtat
    51301 taaggctaga cagacgtctg gaaggaaatt tcaatcaaat tattggtgtg cagggttttt
    51361 gagtgacctg gaatcacaat agattggtca atcttacgct ttaagaaaaa ttcgcgaatc
    51421 acttcaagct cgtcctcttt gatggcacga tatttatttg aaatgagtag ctcataatgc
    51481 ttgggtgctt gcgtaaagat gacgtcagtg ttaccagctg agtaaacttc aacgaggtga
    51541 gcatctgtat tttgcagctg atttctgaca agctcggggt gactgctggt ggtattaata
    51601 agtctcataa atcttctcct gactattttt acttttatta tagcactatt tttaaattga
    51661 ttacggattt taatggtgct ttttctgcca ttcttcgacg ccccatctgt ggctatcacg
    51721 ctttaagact gttatggcgt ccgcaatagg aagaaaccaa gccagatggt taaagtcttc
    51781 caagggcttt gagatagctt ggaatgatgt cacctcgtac aggtaggcag gattatagta
    51841 gtaggtatcg cggtgacgag aatagaagta ttcgtctgct tgaccataat aataaccaat
    51901 atcagcagca aatcccagct cctcaactag ctcacgctcc agtgcctgta gctggctttc
    51961 accagcctct atttctcctc ctggcaaaaa ccaagcacca tttggagcct gcactaggat
    52021 aatctctgtt ttagccgagt taggaatcac tgcatagaca ccgtaacgtg cggtgtaatg
    52081 ctggtcatct atcttatcac caaatattgg aacggtcata tcgcttctcc tttgttttat
    52141 tatactaaat ttttggtcat tattctcata aaactgtaga tttatcaaaa atgtttcata
    52201 aaaaaatgct cgtcaaaaag agagaaaatg ctgtctgctt ttctctctgc ttttctctct
    52261 gctttttggt atgccctgtt agtccgcctg cttcgcctga gatttgacta caggcttgat
    52321 tataatgtgt ccattagagg tcaagacagc tcgcatgtct ttttctgctg ggtgctcaag
    52381 gtagaagtca gtaatggcgt cctcaatgta gtcctgaatg gtgcggcgca atggtcgtgc
    52441 tcccatctta ggatcatagc ctagctcaac gagcttttct ttgacctttt gggtgacatc
    52501 aaggcgaatg ttattgtgag caaggcggtg gttaacatca tcgagcatta aatgaacgat
    52561 atgtaaaaga ttgtccttgc ttagtggctg aaactcaata atgccatcaa agcgattcat
    52621 gaactcgggg ctaaagaaat gactgagctc tcctaaaaca gagtttgtcc gcccttctct
    52681 agcagcgcca aagcctactg aggcctctgt tttgccagtg ccagcatttg atgtcatgat
    52741 gataatagtg tccttaaagc taacggtacg tccttgtccg tcggttaatc gtccgtcatc
    52801 taggacctgt aaaaacatgt gcatgacatc agggtgagcc ttttcgatct catctaacaa
    52861 aatgagcgag taagggttgc ggcgcacctg ctctgttaac tgacctgcct cctcatagcc
    52921 gacgtagccg ggaggggcac cgacaagctt agccacagcg tgcttttcca tgtattcaga
    52981 catgtcaaag cgaatcatgt tatcagcaga gccaaaaagc tcaatggcta attgcttgga
    53041 aagctctgtt ttaccgacac cagttgggcc aacaaagagg aaggagccga taggacgatt
    53101 tggggctccc agtccaacac gattacgacg gatagctttt gcaattttat caacagcatc
    53161 gtcttgaccg ataacatgct ttttgagatc ggcggccaga ttgactagct gtgattgttc
    53221 cttttccttt aaatcaccaa ctggaatatt ggttttttgc tcaacgattg cttcgatggt
    53281 cttgtcagtg atgattggaa tatcctgctc atctagcttt tgagcctgca tttctttata
    53341 tttggcgatt tgatcgcgga aataggctgc tcgctcataa tcctcatcac gtgtggcttg
    53401 tgtcttgagg ttttcagcct caatcaaacg cttatcaatg tctttggggt caacaaagtt
    53461 aagggttagg ttcatctttg agccggcttc atctagcagg tcaatggcct tatcaggcaa
    53521 gaagcggtct tgaatatagc ggttggagag gttagcagct gcttcaatag ccgactggct
    53581 atatttgaca tggtgatagt cctcatattt gggttggatt ccttttagga tagtgattgt
    53641 ttcttcaacc gaaggctcgt ccaccttaac cggctgcatg cgtcgctcaa gggctgcgtc
    53701 cttttcgatg atgcgatatt cattgagagt ggtcgctccc actaattgaa gctcaccacg
    53761 agcaagtgct ggctttaaaa tatttcctgc gtccatgctg ccgtcaccaa ctgcaccagc
    53821 tcccacaatt tcatggattt catcaataaa tagaatcacg tcatggcgct tgcggatttc
    53881 ctccatgagc ttttgcatgc gctcttcaaa ttggccacga atacctgtcc cctgaacgag
    53941 gctaaccaca tcaaggcgaa tcacctgctt actctgtagc ttttgtggca catcgccatc
    54001 aacgattttt tgagcaaggc cttcaacgac agcagtctta ccaacacctg gttctccgat
    54061 taggacaggg ttatttttgg tacgacggtt gagaatctcg atcacgcgga taatctcatc
    54121 gtcacgtccg atgacaggat caatatcacc acgcttagcc atttcagtga tattaatgcc
    54181 gaattcctca agcaaacctt tgttagcctc ttgtgctggc tgtgtgtgat tgggacggta
    54241 gccattgtga cctccgccat tatggccgcc tgattgggta ggtggtgtat tgggcaattg
    54301 accgaaggct ctaaaattgt tcaggtcacc aaaaaagtca tcaaagaaag ggttttgaga
    54361 aggctgctgc gccttttggt tgccattata gcctcctaag ataggatttt tagggtctgt
    54421 tttcatgatt tggtagcaat tttgacagag gtcaatctgc ctttgctttc cgttaatgct
    54481 tgtataaaga tgaatggttg attcgtttaa attacagttt tgacaaagca tatcatacct
    54541 ccaaggggtt atctaaaaag tcaaggtcat ttagtcaaaa atggtcaaac tttatagtca
    54601 tattatagca ccttaggctt ggaaatcaag taaaaagctt cattattagc actttcaggt
    54661 atagagtgat aatctctata aatcttgctg ctcattggtt caaaaaagtc gtcaaagggg
    54721 ataaaataaa gagaaaatgg ctacttttct tgtttgtttt cgatgattta tgttaaaata
    54781 tatagggaca ataaacgaat aggagaaacg aaatggaatc acatttagtg agaatcatca
    54841 accgtctgga gctgatggta acagatggcg gtaatttaaa gagaaacttt gagcgagatg
    54901 gtgttgttgt tgcagaggtt gcatttgtca acgatcctga aaatggtcca gtctttattt
    54961 tacgtgatat tgaagcgcgt gagtcatatt catttgatag catcgatttg attgcgatgg
    55021 aaatttacga tttgttatat taagctattg atgatgacat gggcttgctg ggaggcaggt
    55081 cagacagagg acaagctggt gatttactgg tttgttttta ttatccctta aagcctcaag
    55141 acagctccag gaaaggcctt tctcctatgg tctttctagc cggtagggct tgatagtgat
    55201 taatagtgat ctgctctagc acggtcttga gcttttactg tcagaggctt gtgaccttag
    55261 ccactcgcag taaagggtac tggcccagta agcaaggtag gctaagtatc aatgtgaagt
    55321 tctaaccttg atcttagtga aatatttttg aggtgaatta agatgttaaa agtccttaga
    55381 atgctcattt ctaagggttt tgttgtgtct agctgttggt gtttgaaaga gcggtggtat
    55441 gataaagaga ggtcagaaaa gacctctctg atgtttgtga ttagctgtta gctattgcca
    55501 taggggaaag acacaatagc tagcttagct tttctttttc tttaggttta ggacgcctgc
    55561 gctagtgatg acgctaaggg ctgcaagggt gaagaatggg tgatttgtct cccctgtagc
    55621 tggtagcgtg ctcttttgag ctgctggtgc tgacttaggc gctggtgctt taggctgagc
    55681 tgatttttct ggagcctttg gtgcaggtgt cttttcaggt gcttttggag ctgatggttt
    55741 tgtatctttt ccttgatcac cctttggttt ttgctcgcct ttttcgccgc gttgtccttg
    55801 ctcgcctttt tcgccgcgtt gtccttgctc acctttttca ccgcgttgtc cttgctcacc
    55861 tttttcaccg cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cacctttttc
    55921 accgcgttgt ccttgctcgc ctttttcacc gcgttgtcct tgctcacctt tttcaccgcg
    55981 ttgtccttgc tcaccttttt caccgcgttg tccttgctcg cctttttcgc cgcgttgtcc
    56041 ttgctcacct ttttcgccgc gttcgcctct gtcaccctta gggccggctg gtccttgttc
    56101 acctttagga cctgtttctc cggtttcgcc tttatctcca cgtggtccca taggcccaac
    56161 aggaccttgc tctccgcgtt cccctctagg tccggcaggc cccacaggtc cctgaggacc
    56221 acctttttta gcttgtagtt ctaagttttg taagtaggtt tgcatgaatt gtcttaatgt
    56281 atgtaggtat actcttactt cgccatctcc gagtccgtcc ctaattagtt cagctggatc
    56341 tggataggac tctaatcgcg tataatcttc agctcgggca tttccagctg ttcctaggct
    56401 ggccattgtt gctagggcaa tggctgctga gcagacgctg tacttgcgta ttgttttttt
    56461 catctttctc tcctttgatg atagtatcat tactttttca aaattctttc ccgaagaaga
    56521 gtttaacatg gtagcttgct atgagaaaca gctaggcgcc actttgtctc cgtagttttt
    56581 ttaattcaat gctgaatcgt ctgattttat cagagggtta ttgtttttaa aggcgaggag
    56641 ttgctttgct cagctagtct agcaagttca caggtcagct tatgtttctt atcaagcttg
    56701 tttgtttttg agaatatttt tcgataaaaa gatgttgtat taatattcat gttatagtat
    56761 aattatattc gttgccatga ctttatgaat gttaggagat aggaatggat tttacctttt
    56821 tacccaaata ctgggcttat ttcaattatg gtgtgcttgt aaccatgatg atttcagcct
    56881 gtgttgtctt ttttggcacg attataggtc ttttagtgac cctgataaaa cgcagtcata
    56941 tcaagccttt gtcttggctt gtcagtcttt atgtctggat ttttcgtgga acgccgatgg
    57001 tggtacagat catgattgct tttgcttggc tgcatttcaa cgatctgccc attgtaggct
    57061 ttggtgtgtt ggatttggat ttttcaagac tgcttcctgg tattattatt atttccttga
    57121 atagcggtgc ttacatatct gaaatcgtca gggctgggat tgaggcggtg ccaaaggggc
    57181 agctggaggc tgcttactct cttggtatcc gtcctaagaa cgccatgcgc tatgtgattt
    57241 tgcctcaggc ctttaagaat attttgccgg ccttgggcaa tgaattgatc accattatca
    57301 aggatagtgc cttgcttcag acgattggtg tgatggagct ttggaatgga gctcagtcgg
    57361 ttgtgacggc gacctatctg cctattacac ccttgctgtt tgcggccttt tattacttga
    57421 tgataacaac aatattgtcg caattattag gctgcttgga gcgcaagcta gcacagggag
    57481 ggagataaga tgactgagac agtgatttcg attcgtcagt tgcataagag ctttggcaag
    57541 catgaggtgc taaaaggaat agacctgacc attaatcagg gtgaggttgt ggtgattatt
    57601 gggccatctg gctcaggaaa gtccacgcta ttgcgcacga tgaatttgct tgaggtgcca
    57661 acaaagggac acatcagctt tgagggcgtc gatattacgg ataaggcaaa tgatattttc
    57721 aagatgcgtg agaagatggg catggttttt cagcagttta atctgtttcc caatatgaca
    57781 gtgctggaaa acatcaccct gtcacccatc aaaacaaaag gaatgtcaag ggctggcgcg
    57841 gagcagagag cttatgagct gcttgagcga gttgggctga gagataaggc tgctgcctat
    57901 ccggcaagct tatccggtgg tcagcagcag cgcattgcga ttgcgcgcgg cttggcaatg
    57961 gatcccgatg tgctgctctt tgatgagccg acctcagcgc ttgaccctga gatggtgggt
    58021 gaggttttgg ctgttatgca ggatttggca aaatcaggca tgacgatggt tattgtaacg
    58081 catgaaatgg gctttgccaa agaggtggcg gatcgcgtga tttttatgga cggtggtctt
    58141 gtgattgaag agggcagtcc agttcaggta tttgaagctc ctaaggagga gcggaccaag
    58201 gactttttga gcaaggtatt gtcatagctg gcgcagctaa agggcagcat gtcacctcaa
    58261 ggtctggcta ttagtcaatt ggctgtttgt tttgggcatt ttgtttgtaa aaggcttaga
    58321 aagtctggtt ggtgctgtag ccatatctgg ctttgctacg cttgggctgc tagctggtca
    58381 gtgggtatca tagtgattgg aggtgtggtc tctttattgg tcaacattgc tgtggcaggc
    58441 tagcacaggg gctttgcttg ttgtgctggg taaggggttt catttgcatg actgttaaca
    58501 ttgcttaatt gatgaattag gttgactttt gttttattgt ttgatactat tcaggtaagt
    58561 ctgtcattag aaagcgcttt gcttttttga tgatggaaat catgatcata tgatcacgtc
    58621 ttaggtaata tgttgttgtc aacatggtgg tctgaaagta ggaggataat atggactaca
    58681 aagctgttta tcaggagtgg ctgcacaatg attttttcaa tgaagaaatc aaggcagatt
    58741 tagaggcgat taagcatgat gaggctgaga ttcaagaccg tttttataag gtgcttgagt
    58801 ttgggacagc aggacttaga ggaaagctcg gtgctgggac caaccgtatg aatatttaca
    58861 tggttggtaa ggctgcgcag gctttagcta ataccattat tgatcatggg ccagaggcag
    58921 tctcacgcgg gattgccatc agctatgatg tgcgctataa gtctaaggaa ttcgcagaat
    58981 tgacctgctc gatcatggca gccaatggga tcaagtctta tatctacaag gggattcgtc
    59041 cgacaccgat gtgctcttat gcgattcgtg ccttgaactg tatctctggt gtcatgatta
    59101 ctgctagtca caatcctcag gcctacaatg gctacaaggc ttattgggaa gaggggtcac
    59161 agatcctaga tgacattgct aatcagatag cggttcatat ggacgctatt gagcgctttg
    59221 aggacgttaa gcagataccc tttgaggagg cattggcaag tggtctgacc agctatattg
    59281 atgatagtat agaggaggcc tataagaaag aggttttagg cttgaccatc aatgatactg
    59341 atattgataa gtcagtgcgt gtggtttata cacctttgaa tggcgttggt aatttgcctg
    59401 ttcgtgaggt attgaagaga cgaggctttg atcatgtctt tgtagtgccg gagcaggaaa
    59461 tgccagaccc agatttcaca acagttggtt atccaaatcc agaggtacca aaggcctttg
    59521 cttattcaga aagactaggg caagaagtag gagcagctat tctgattgcg actgatccgg
    59581 actgtgatcg tgtggcacta gaggttcgag ctgctgacgg tagttatgtc tttcttaatg
    59641 gtaataagat tggtgctttg ttgtcctact atatcttttc acagcgtcat gctaggcata
    59701 atcttcctga caatcctgtc cttgtcaaat caattgtaac aggggattta tcaaaagcta
    59761 ttgccgctaa atatgacgtt gaaacggttg agactcttac aggctttaaa aacatctgtg
    59821 gtaaggctaa tgactatgac atcacaaagg agaagaccta cgtctttggc tatgaggaaa
    59881 gcattggttt ttgttacggt acctttgtgc gtgataagga cgcggttagc gcctcaatga
    59941 tggtggtaga aatggctgcc tactacaagc aaaggggtca gtcactctta gatgtgcttc
    60001 aagacattta caaggaattt ggctattaca atgagcgtca ggtagcgcta gagctagagg
    60061 gtgttgaggg gcagaagcgt attgcacgta tcatggagga ctttagaaat gagcctattg
    60121 agcatgcagg tgctatgagc ttgaagacca ttgtagactt taaggacggc taccttgatt
    60181 ttccaaagca aaattgtttg aaatattatt ttgatgatgg gtcatggtat gcgctgagac
    60241 catctggaac agagcctaag atcaagcttt acatctatac tattggtgaa acagaggcag
    60301 acagcattgc taagctagac gctattgagt cagcttgtca agcaaagatg gacagtgtca
    60361 gctaattgtt caagctctgc aacagaaaat cagctaatca ataagcaaaa aggaaaagga
    60421 agtgacagtg cttccttttt tcgttataat agttaaaaaa ttagcaagga gtgcatatgg
    60481 tacagattat tgatgggaag gccctagcac agaaaatgca ggcagcattg gctaagaagg
    60541 tagagagctt aaaggcagaa aaaggaattg ttccaggcct tgttgtcatt ctggtaggag
    60601 acaaccctgc tagtcaggtt tacgtccgta ataaggaacg cgctgcctta gcagcaggct
    60661 ttaaaagtga aaccgttcgc ttgtctgatt cagtctgtca ggaagagttg atagagctca
    60721 ttgagcaata taatcaagat gatacgattc atggtatttt agtgcagctt cctcttccgc
    60781 accatattaa tgacaaaagc attatccttg ctattgatcc taaaaaggac gtcgatggct
    60841 ttcaccctat gaatacaggt catctgtggt caggtcgtcc gaatatggtc ccttgtactc
    60901 cggcagggat tatggagatg tttcatgact atggtatcga acttgaaggg aaaaatgctg
    60961 ttattgtcgg gcgctcaaat attgttggga agcctatggc gcagctactg ttggataaaa
    61021 atgctacggt aacgcttacc cattcgcgca cgcgccgact ggcagatatt tgtcgtcgtg
    61081 ctgatatctt gattgttgct attggtcagg ggcattttat cacaaaggag tttgttaaag
    61141 agggtgctgt tgttatagat gttggtatga atcgtgacgt caatgggcga ttgattggag
    61201 acgtcgcctt tgatgaggtg tcagagctgg ctagcatgat tactcctgtt ccgggtggtg
    61261 ttggaccgat gaccattact atgcttttgg agcaaaccta tcaagcagct ctaagaaggg
    61321 tgagtcaatg attatagatc aatcgtttgt tgctagggtt gttgttccgc ggcaggctga
    61381 ctcccataag gggagttacg gcagagtact gttagtaggt ggcttgtatc catacggtgg
    61441 tgctattatt atggtagcgc tggcctgtgt tcatagtggt gctggcctag taactgttgc
    61501 aactgataga gaaactattg ctgccttgca tagtcatttg ccagaggcga tggctattgc
    61561 ggtagatgat gaggaattac tgttatctca gctaggtatg gcagacctga ttttgattgg
    61621 tccggggctg tcggagaata gcagagcagc taggctgttt gaattggtcc ttgcacatgt
    61681 cgctgatcat caggtattgg tcattgatgg ctctgcctta aggcttttag cgaaaagggc
    61741 agctgatgtt aagcagctga ggtgccctct tgtgttaacg ccacaccaaa aggaatggga
    61801 ggcgctgtca ggtttagcga ttgatcagca gtatgatgct gccaaccaag cagctctcaa
    61861 gcattttcca agggctacga ttttggttgc taaaagctca gcaaccaaga tttatcatgg
    61921 caaccagatc taccggctaa gagtgggcgg accttatcag gctacaggtg gtatggggga
    61981 taccttggca ggtatgatag cagggatagc tgtccagttt ccagagtcaa gcttggtggc
    62041 taaggttgct tgtgcgacct atctgcactc tgcgattgct gatgagctgg caaagactgc
    62101 ctatgtggtt ttgccgactg ctattagcta tgagcttcct agatggctaa aggcaatcag
    62161 cacaggccag aagctaggtt gaggctgtgc tgcgaggtcg tttgggaaaa gcggttaatt
    62221 ggtaggcatg acagcagctg gtttcagtcg tttagctatt ttgagtttag agctgctagc
    62281 ttaagactgg gtgctgcttt atgattcaag gaagctatca ttggaaaaac ttgtgtcaag
    62341 ctgtagaagc cctagctggc ttcttttttt gtctcttttt tgctcactat ttatgtggaa
    62401 acatgatata attgcattag tatacagttg gagcagttag gcttcatgaa gtgaaaggta
    62461 aactgatggc agactattta tccgtcactc agctgacaaa atatttaaaa ttgaaatttg
    62521 atcgagaccc ttatctggag cgtgtctatc tcactggtca ggtatctaat ttcagaaaaa
    62581 gaccaaatca ccaatatttt tccttaaagg acgagggagc ggtgattcag gccaccatgt
    62641 gggcaggagc ttataaaaag cttggctttg atttagaaga gggcatgaag ctcaatgtgg
    62701 ttgggcgtat tcagctctat gagccaaatg gctcgtattc aatgatcatt gaaaaggctg
    62761 agccagacgg tattggtgct ttggcgctgc aatttgagca gctcaggcaa aagctggctg
    62821 gtgaaggctt ctttgatgag aggcataagc aggccctgcc gcaatttgtg acaaaggtag
    62881 gtattgtgac gagtccaagt ggggctgtga ttcgtgatat tatcacaacc atctcaaggc
    62941 gttttcctgg ggtgagtatt cttttgtttc caacaaaggt tcagggtgag ggggcagctc
    63001 aagaggttgc tgctaatatt actaaggcta accagcgtga ggatctggat ttgttgattg
    63061 ttggacgcgg cggtggctcg attgaggacc tgtgggcttt caatgaggaa atcgttgttc
    63121 aggctatttt tgagtctcgc ctgcctgtta tttccagcgt aggacatgag acagatacaa
    63181 ccttggctga ttttgtggct gatcgcagag ctgccacccc aaccgcagct gcagagctgg
    63241 cgacacctat tacaaaaaca gatattgtct cttggattgc tgagcagcag agccggtcct
    63301 atcaagcctg tctgcgctat atcagacaag ggcaggagcg ggtggataag ctttcttatt
    63361 ctgttatttt caggcagcca gagaggctct atgatgctta tagtcaacgc ttagataggc
    63421 ttacgacctc cttgatgacc acttttaaag agacattatc aggagctaag caggagcact
    63481 tgattttgga gcatcgttta gcctctgtca atgtacaggc aaggcttgag cgttatcagg
    63541 atcgtctggc aactgcgcat cgtctcttga tagccaatat gaccaatcaa tatgacagta
    63601 agctagcagg ctttgagcga gctcaagctg ccttgctgtc gcttgatacg agccgtatca
    63661 ttgcccgcgg ctatgccctg ttaaaaaagg acggtgtagt agctgcttgt gttaaggaca
    63721 ttaaaaaggg agatcatctt agtattatca tgcgtgatgg tcaattagaa gtagaggtag
    63781 aagatgtcaa cgaaaaaaat atttgaagag cgtttacaag aattagaggc cattgtgacg
    63841 aggctagaaa atggtgatgt gccactagaa gaggccatct ctgaatttca aaagggtatg
    63901 gtgctgtcca aggaccttca aaaaacctta caagcagctg aaaagacact tgttaaggtc
    63961 atgcaggcag atggcacaga gctagaaatg gatgcctaat ggataagcta acaagaatta
    64021 atgccacgat tcatcagtat tatgacaggc agtctactgt ttcagcagat ctggaggagg
    64081 ccattttata ttctgttgat ggtggaggaa agaggctccg tccactcatg ttattggagc
    64141 tgctagaggg ctttggtctt gccttgacag acgctcatta cgcggttgct gctgctgttg
    64201 agatgattca tacaggaagt ttgattcacg atgatttgcc tgctatggat aacgatgatt
    64261 accgtcgcgg gcgactaact agccacaagc aatttaatga agcaactgct attttggcag
    64321 gagatagtct ttttttggac ccttttgctc taatcgcagg ggcagatttg ccggctgacc
    64381 tgctggtgca attgattcag cagttttcct tagcgtcagg aacctttggc atggtcggtg
    64441 gtcagctctt ggacatgaag ggtgagcatc agctgctgga tattcaggag ctatctgata
    64501 ttcatgccaa taaaacaggg aaattgttga cccttccttt tgtggctgcg ggtatcatag
    64561 ctgagcagtc agcagacgtt ttgtcttgtc tgtgggaggc tggtaggctt gttggacagg
    64621 cctttcagat aagagatgat atattagacc ttacggctag ctttgctgat cttggcaaga
    64681 caccgcaaaa ggaccttgct gctgcaaaat caacctatcc gagtctgctt ggtttagagc
    64741 gctcaagggc tattttggag gagtctttga gtcaagcgct agctattttt agcagactag
    64801 aaagggaaga aggctttgag tctcaggcta ttatcaaaag gatcgagggg ttgcgactaa
    64861 atggctaaag aaagagtaga tgtgctagcc tatagacagg gactttttga aacgcgagaa
    64921 caggccaagc gcggtgtgat ggctgggcta gttatatcag ctataagtgg cttacgcttt
    64981 gataagcctg gtgaaaagat tgatgagggg atcgaactaa ggctcaaggg tgagaagctt
    65041 aagtatgtca gccgaggggg tctcaagctg gaaaaagcct tgcaggtctt tgggatctct
    65101 gtgcaggata aggtgacaat tgatattggt gcttcaacag gtggctttac agatgttatg
    65161 ctacaggcag gagctaggct ggtttacgct gttgatgttg gaaccaatca attggtctgg
    65221 aagctcaggc aggatagtcg tgttcgaagc atggagcagt acaattttcg ctatgcaaag
    65281 ctagcagatt tttcagaagg tcagccagcc tttgccagca ttgatgtgtc ctttatttct
    65341 cttagcctga tactgccgac attgcactgt attttgcagg aaggggcaga ggctgttgct
    65401 ctgatcaagc cacagtttga agcagggcgc gagcagattg gcaaaaaagg gattgtcaag
    65461 gatagactga ttcatgaaaa agtgattaag caggtggcag atactgctct taattgcgga
    65521 tttatcgtta aggggcttga tttttcgcct atccaaggtg gtcatggcaa tattgaattt
    65581 ttggctcatt tagtcaaggg aaagggctcc aaggctattg atgatcagct catacagagc
    65641 gttgttagca gtgcacataa ggaatttaaa cagcatgaaa aagagtgaac gattagattt
    65701 aataaaaaaa atggttttgt ctcatgagat tgagactcag catgagctat taaagctcct
    65761 agctgattat gggctagagc taactcaggc cactatttca agagacatga atgaaattgg
    65821 cattgtcaaa attccatctg gaactgggcg ttatgtctat ggcttgtcac aggatagtgg
    65881 caagcgggtg gtgcaaaggc ctgcctctat caaaaaaacg attttggaaa tgtctgaaaa
    65941 aacagcgggc ttggagcagc atattcacct caacgttgtt ccaggcaata gcaagctaat
    66001 caaacgttat ttgatgacag acttttcagg tcaattgttt agcctgattg cagatgatga
    66061 tagtttgctg ttgattgcaa aatcagaagc agacgctgat catatccgtc aggaattgtc
    66121 cctttggatg cagggattgg tctaaaaaat agagagaagc cgatgttatt agaaatttcc
    66181 attaagaatt ttgctatcat agaggaaatc tctttaaact ttgaaaacgg tatgaccgta
    66241 ctgactgggg agacaggggc aggaaagtcc attatcattg atgcgatgaa catgctgctg
    66301 ggtgcgcgcg caagcactga ggtgattcga catggtgctg ataaggcaga gattgagggc
    66361 ttcttttcgg ttgatgctaa tcctcattta gccgctgtgc tggcagaatc agggattagc
    66421 atggaagagg agttgattct tcgtcgtgat atttttgcta acggtcgtag cgtcagccgt
    66481 atcaatggtc aaatggtcac tgtcagcacc ctaaaaaaac ttgggcagtt tttagtggat
    66541 attcatggtc agcatgatca ggaggaattg atgcgtccac agctgcacca gcatattttg
    66601 gatagttttg gagatgaggc ctttgaccag ctcaagcagt cctatcagca gatttttgat
    66661 cgctataagg ctttgcgaag gcaggctctt gagaagcaaa aaaatgaaaa agaacatcag
    66721 gcgcgccttg acctgctggc ctttcagata ggggaaattg aggcagcaga tttggttaga
    66781 ggagaagatg acctgcttaa ccaagaaagg cagcgattgc tcaatcacaa aaagattgct
    66841 gataccttaa ccagtgccta cctttccttg gataatgagg acttttccag tctctcacag
    66901 gtccgctcta gcatgaatga gttgctgtct attgaggacc ttgccccaga gtatcagctt
    66961 atatcagctg gtgtgtcaga ggcttattat attcttgagg aggtcacaaa gcaattatct
    67021 gataccatcg accagcttga ttttgatgca ggcagattgc aggacattga gctgcgttta
    67081 gacagcatta atagtctgac aagaaaatat ggcggtggtg tgaatgatgt tttggactac
    67141 tatgccaata ttaccaagga ataccagtta ttaagcggag atgaccgttc ctctgatgag
    67201 ctagaaaggg aattaaaggt ccttgagaag caactggtga tgactgcctc acagctaagt
    67261 gacaagcgtc atgccctggc tctagagcta gaagccgaca tcaaagctga gctgagagag
    67321 ctttatatgg aaaaggcgga ctttaaggtc cactttacaa ggtcaaagtt taatcgagaa
    67381 ggcaatgaaa gcttagaatt ttatatctca accaatccag gtgagggctt taagccgctg
    67441 gttaaggttg cttcaggtgg tgagctttcc cgcttgatgc ttgctatcaa ggctgccatt
    67501 tctaaaaaag aggacaagac gagtattgtc tttgacgagg tggatactgg agtttcagga
    67561 cgtgtggccc aggccattgc taaaaaaata tataaaattg gcagctatgg tcaggtatta
    67621 gcgatttcgc atttgccaca ggtggttgct attgcagata accagtattt tatttccaag
    67681 gaaagcaagg aggagtcgac agtgtctaag gctaagctgt tgacacagga ggagcggatc
    67741 gaggagattg cgaagatgat tgcaggagct gatgtcacag agacagcaag aaatcaagcg
    67801 cgtgaattgc taggtaagga ctgagtatca tagcaaaagc agaacagtag ctttagagca
    67861 agcttgcctg ctgcacttgt cgctacatgt tcagaatgag ccacctgaaa ggcaagcaag
    67921 aaggctagct cttatgcgta tgctatcaga agctaagtct ttttgtctct tgcattggcg
    67981 agtgattgat tgataatatt atgataaata gaaggactaa aagaatactg actgaggagg
    68041 taaaatgctg aaaaaaagaa tgggcttggc tagtctgcta gtgttgatga cctttgtgta
    68101 tcagtgctgt tcagttactg ctgagcagta ttccgatact gaggttgagg tgctgcagat
    68161 tagcgaggag aaaagccaga tcatggaaaa tcaagaggcg cttaaagacc tcaccacgtc
    68221 gtctgatcag ctaaagaagg aagctttaaa gcctaaagag gcagctacca acaagagcaa
    68281 gcaagaggct tcgacagttt atttagctga ggacgatcct gtaaccattg atagctctga
    68341 cgaggaaagc aatcaagata tcatagcgga ttctgttcct gatttggtta ttaaaggtga
    68401 tcaggtggat gtatctgagg ttatggtctc tgtaaaggag gattcatcga aagttgctaa
    68461 gcaaagaact gacgcagcgc agcggtacag tatagccaag catcaattga cccaaaagct
    68521 tgaggccttt aatgcggcaa cggaccaatt gctgaccatg attgctaaaa aatctgattt
    68581 gactggtcag tattatgtgg ttgggcattc gttgggagaa atgctggctg ctcaaaatga
    68641 gaaaaagctt gctgagcaat tagtcatgca acaaaagcac aaaaaaggct taggctcatc
    68701 agtcactatt ttagacgaat taggacgtgt gatttctgac attagtggtc ataaaggcat
    68761 gcttcctttt aatcgtaaga tcagctttaa ggtacatcaa gtcagatacg atcttccact
    68821 aactggtgat cgaacagtgc tacctgccca gctggctggc ttactgcttt tactaatagg
    68881 tcttatgctg cctaaagtag ctaacaagaa aagctaagat atggtcttgg cttttttatc
    68941 ttttaagagg gtgagttttt gacagatgtt ttagctaaca ccaagagcta gataccagct
    69001 ttgctttatt tttaaaggag tgataaaata aagagacgat aaatgaggtt agaaatggaa
    69061 cttaagatgg gaactattaa aattgttgca gattcatcaa tgacgattga accagagcta
    69121 atcaaatctc ttgatattac ggttgtaccg ctttctgtca tgattgatag caagctgtat
    69181 tctgataatg agctaaaaga ggaagggcaa tttctacagc tgatgagagc tagtaagtca
    69241 ttgccaaaaa ctagtcagcc accggtaggg ctttttgcag atatttatga gcgattggtc
    69301 aaggaggggg cgacagctat tgttgccatt cacctctcac cagctctttc aggaacaatt
    69361 gaggcatcac gtcagggagc tgaaattgca gcagcaccag ttacggtatt ggactcaggc
    69421 tttacagatc aggctttgaa gtttcaggtg gttgaagcgg ctagactggc tcaagctggc
    69481 gctagccttg aggaaatcct tgaggcggta gaggatatta aacgaaagac agagctttat
    69541 ataggggtat cagcacttga gcacttggtt aaggggggac gaatcggtcg tgtgacaggc
    69601 ttgcttagct ccttgctgaa tattcgtgtg gtcatggaaa tgaaaaatga taccctgcaa
    69661 acacttgtta aaggacgcgg caataagacc tttactaaat ggctggatag ctatctagca
    69721 gaaaatagcc agcgacagat agctgaggtg gccatttcct atgctggtca gagggatttt
    69781 gctgatagcc tgaagaagac aatcgctacg gtctttgatg ggccaattac tgttttggag
    69841 actggctcaa tcattcaaac acatactggc gagggcgctt ttgcggtgat ggttagatat
    69901 gaataagcga gggtttttgg gaggccttat cttctttttc agtgtttttg ccttatcatt
    69961 tgtgatatta gctgtcctta ttccaaagtc tgacccacag ctgaagaaaa gtgattttct
    70021 aaaaaataag aagataagcc tcaattatat tgctattgga gactccttga cagagggagt
    70081 gggtgatctc accaaccaag gaggctttgt gcccttattg tctggtgatc ttggagacta
    70141 ctttaatgct accgttaata ctgaaaatta cggtgtttcc ggtaatacca gccagcaaat
    70201 tttaacgaga atgactgaga acaaggagat cacagagcag ctcaaaaaag ctaatctcat
    70261 gacattaacg gttggtggca atgatgtctt ggctgttatt cgcaagaact tagctaatct
    70321 taaggtatca agctttaaaa agccagcaag gcaataccaa gagcgcttac gcaaaatcct
    70381 tgatttggcc agaaaggata atcaggatct gccgatcttt gttttaggta tctacaatcc
    70441 tttttatttg aattttcagg agctaacaga aatgcagacg gtcattaatg actggaacaa
    70501 aaaaacacaa gaggttgttg atgactatga ccatgtttac tttgttccaa ttaatgatct
    70561 attgtacaaa ggagtagatg gtaaagaggg cattgtccag tcaacaggag agcaaacaac
    70621 gattgtgaat gatgctttgt tttcagggga tcattttcac cccaataaca caggctacca
    70681 aatcatgtca gacgcagtaa tggagacaat aagaaagaat ggaaaagaaa ttaaacctta
    70741 attggtggaa atgggctttt ttgctattat tggcttttaa tgcagccttt ttagcagtta
    70801 ttggaagtcg tattatacaa ataagagagc ctaagtctga gctgatcaat caaaaagcag
    70861 caaagaatat taaaataggg accttaacaa ccactaaaga gcaattaaat gaggcagtcg
    70921 ttagctacct aaaggatttt cagacggaaa aaatgaccta taaggtgtat gccacctcct
    70981 cgaccattct ctttgaagga acctatcagc tcttaggata tgaggtgccg ttatacattt
    71041 attttcagcc tcatcgctta accaatggtg cgatacagct gcaggttctc tccttttctg
    71101 tggggaccct ttctttgccg gaaaaggacg ttttgcaata cttgaaatcc agctataagc
    71161 tgccaaaatt cgttgaagtc ttacctaagc aatcggctat tattatcaat ctacagcaat
    71221 tggaaaatga tgccaacatc tatttaaagg ctcaaaagat tgatcttgtc aaggatgata
    71281 ttcgatttga catctataag aaatgagtct aactaacgtt taatacttga cctgtggctg
    71341 ttttttagat atgataatat ctgttaaagc gttaagctta ctaattattt ggaggattgt
    71401 taaatggcta acaaacaaga tttaatcgca aaggttgcag aagcaactga gcttacaaag
    71461 aaagattcag cagcagcagt tgacgctgtc ttttctgcaa tcgaagcttt tcttgctgaa
    71521 ggtgaaaagg tacaattaat tggttttggt aactttgagg ttcgtgaacg cgctgctcgt
    71581 aaaggtcgca acccacaaac tggtgaagaa attgaaattg cagcttcaaa ggttccagca
    71641 ttcaaggctg gtaaagctct taaggacgct gtaaaataat aaatcaaaaa aagccctatc
    71701 tcattaagct gtttagcctg tgagataggg ctttttccat taaggaagga gtcttgtttc
    71761 aataagtaat cttgtgtgat cgtctgaaag attagcgcca ataatttcta atgtgcactg
    71821 tcttgggaac aagagttcca tttcataagg ataaaatgag tagggctgta caaaagcagc
    71881 ctggctgcct tgagggacct gaattcttaa ttccactgag cgatgtggca tagcagcatt
    71941 tttgatggct gtagtactca taaagccttg ctttgtataa tgagtgcctg gcttgatcgc
    72001 tgataggatc tgcggatcaa aggtcttatc atggtagtaa cgagcgagtt cctcttcaga
    72061 agtgcccaat tctgttaaga atgtttcata aacatagcga tagacgatga tattccaagg
    72121 gatggttagc ttatgagtag cactatcaag taaggctaca gactgctgca gctgggcatc
    72181 caactggctg gtatctccca tcacctgttc tagggctagg ttaatagggc tggcagaggc
    72241 gtatgtatac tgatacatca tctttttttc tgcttctgta aaggctgttt gagacctcca
    72301 gcgattggtg ataatgtatt tggtaacatc aggctcacta aatttataat aaggcttaaa
    72361 gctattccca tagggctcaa aaacaactgt ttgtccttca tcataagact gtgccttgat
    72421 ggttgaaggc tgaacgacaa gcaacgataa gaaaaatgta aacaagcata gtgtacgaat
    72481 agctatcctt tgataagata actttgcgtt atgatgttga tgagtcattt agcttttcct
    72541 cctttacagt agtgccaaga gtgtcatcac ctaatgatga tgtctgttgc taacaggatt
    72601 agccttagtt gaaatgatta caaacttcct taatgtaaca aacataataa aaataaatta
    72661 tttttttatt atatattagt taagctcaga tgacaagcta tttgattttt ttctgagata
    72721 atgttacaag ggatttctaa caccaatgac taactcagat gaagggcttt ttcttggagg
    72781 attgcctata gttacaatag taggcaagac tggcagtcgc catgatacct attccaataa
    72841 cagcaaaggt tgctagatga acagaggctg gtatacaggt catgatggta gttgccagtg
    72901 gcattaagag aatagcagtt gtgacgattg agctaaagac tcgtcctagc aatgcctcag
    72961 gaactttttt ttgaacgata gaaaagaagt gaatgttaaa gattgttaaa aagcattcaa
    73021 accataaatt cccaagggca atcacaatga ctggaagctt caagagagcc atagctgtta
    73081 ttagaagcat ccctaggcca ctaaggccta gggataggag taagctttgc tgattatttt
    73141 taaagagctt gttagccata aaagctccta agatagcccc taaagctccc atcgaaagaa
    73201 gactagcata gcttgattgg ctgcctagca gctgattcga aaaaggaatt aaataattga
    73261 aagcagcaat aaagaaattc acaagagaag caataatcaa caaagaaaaa atgtcattgt
    73321 catggtagat gaattgcagc ccctccttaa tatctgttaa aagctgaagc ctattgcctt
    73381 ggctgctctg tttagtgatg tgcctttctt tgtccttgat tgtatataga catagaaagg
    73441 acaatagaaa gctaatgcta tctagagcca aggctgtttt gatgccaaag caatccatca
    73501 ctaaaaaagc aagcattggt gaggaaatac tgatgatttg agatacgatt tctagctgag
    73561 cattgaaatg aacaagtctt tctgtttcaa ctagtgtgac cacataggct cgaaaagcag
    73621 ttccagagaa ggcatacgat attgctaaaa gagcattaac agtgataagc ccataaagca
    73681 tgatagtagg gttagctatc agggctaaaa gtccgcagct gatagctccg atagcatctg
    73741 tccacaataa caattgtcgt cgtttataac gatcagcaat ggcgccaccg ataggattta
    73801 agatgagtga aataaggcct tcagctagct gataataacc caaatattgt cggccagttg
    73861 ctccgagtcc agcaatcccg ctgctgttgc tgtagtcgta aacagtattg cctattttgt
    73921 taatagctcg acttgcgagc agctggtagt cgtttttgcg catgataaaa cctccaaaag
    73981 attatgtggt tttattataa atcagttttt tagggtctta tgtttttttg caaataaggc
    74041 tagaggaggc tacaaatctt tcaaaatcct tttggtaatt gtgcgctagg tgaggacaat
    74101 ccaggctctc aaaaatggaa atagcagtag tcatatcctt aatgccagac aaacactgtc
    74161 ctctttggta gtcctctaag ccctttaaaa ataaaaagat ggttttttca tatagcttgg
    74221 tttcattatt gagtagggct agtatctgct tttgataata gcgcgcatag tcaagctgat
    74281 gtcggtggat acaggtttcc caaatattga gaagggtgat ggtaaccaaa tgcttattgg
    74341 ttgaaatgct ttcgtagtag gtatgattgt ttagaatttc ctttcccatt ttatctaata
    74401 agggaatatc aataaaaaga tagagatttc caattaaaat cagctcatag atatgccagc
    74461 tttcagtcct aaaaaggtag tcagtgacct catcaagata agccttagga aaaggaatgc
    74521 taggattgca tttacagata aagccttgga gtagaatgct gtttaaatag taacgattgg
    74581 tatcaggatc agcttggtgc tttgccaatt cctgcttttg cagctgcttg aatccctcaa
    74641 tatcgcgtgc atattccagc ttgatcagct gcgacatgaa ttgaatttgc tctgtctgtt
    74701 tgaagttggc agctatgtcc ataaattcgc tgatttccac ttgcatgctg tctaaagctg
    74761 ttaaaaactt tgttactgat agatcagatt cgccgcgttc aaagcgggat aactgagaca
    74821 aggacacgtc tttactggca agctgctgta aggtgatatt tctgttttgt ctaatgctgc
    74881 gaaatgcttt tcccaactga tgattagtca tattttttcc tcctctaatg agtatatcat
    74941 gtaaggcttc tgttgctgta ttttcccgta tgtgcaaacc ttgaaacttg tctgctgccg
    75001 ccacaaaggc atgaaaacat ttacactttt tgatagctat ttttatcatt gatgtagtct
    75061 ttttcgcaac atttgtacgg gatcatcaga ttaaaattaa gaaactgatg atgtgacact
    75121 gtaaacatgc taaaaatatg ttgaacaatg cctgtagctg gaaaatgggt acatgtattt
    75181 tcttcatgcc tgcgtcgtga cctgctgcta ttaaagcttg cttgaaaggg aaaaagagct
    75241 tataatagca gtgagaacat taaaaatgaa agtagagata tgccaataat tgttatcctt
    75301 ggacttgcta tcttttcggt ggttaaggtc attatttttc tatgctttta taaagcattt
    75361 gagaaaaaac aactaaagaa gctagaacag gatcaaaaag aaaccaagca ggcgattgac
    75421 caagaggagt caaaaaaagc ctttcccttt taacataaag ctagaaaaag tctgagacct
    75481 ttcgtctcag acttttttta aggcttatat tgtaattgac cacgaaaatc gtctagtgtc
    75541 tggtagccct tttcagccat aatgtcttgt agctccttag tgatacgctt aaaaatagct
    75601 ggaccttcct ggtgcagtgc tgttccaatt tgtaccatag ctgcgccgca taggatatgc
    75661 tcaaaggcat cacgtcctgt tttgacaccg cctgtgccaa tgatctgaat agaagagtta
    75721 agccgttggt aaaaggcatg aacattagcc agggcagttg gcttgatgta atcaccacca
    75781 ataccaccaa agccgttttt aggcttgatg acgacctgct catcatcaat aaccaagcca
    75841 ttgccaatgg aattaacaca gttggcaaag gctaaggggt attgattgaa aatggctgcg
    75901 gcttggtcaa aatggacaat atcaaaataa ggaggtagct tgatgcctag aggcttggtg
    75961 taataggaaa agatcttttt taggagctga tctgtggctt caaagtcata ggccagctga
    76021 ggcttacctg ggacattagg gcacgacagg tttagctcga caagtccttg ataatcagag
    76081 gcctgaatag cttttaggat agtctcggtt tcttcagcag acatgcccac aacagataaa
    76141 aagtggtgct tgcttgcttg atccttttgc atttctgtga caatatctaa ataatactgg
    76201 tagccatgat taggaagtcc cattgaattg attgagccaa gtgctgtatc tgcatagcga
    76261 ggctcagggt tgccctgtcg aggggctaga gtacctgttt ttgtcacaaa ggacccagcc
    76321 tcagaggcct caatggctag cagctcttcc ttggtcatgc aatacactcc agcagcgttc
    76381 atcaggcaat tattaaaggc aaatgtagcg atttttgtgg cagtagaaac catgttttcc
    76441 tccattttta gacaaatttt ttctattcta tcactagggc atgagaatag caaggcattt
    76501 ttgcaaaata cttgcttgaa ggctttcttt tgtgaggttt tagcgttttt catgatatta
    76561 acaaaatgat tttcaataaa gagaggaata gactagcttt tttgacctat tttttgtaaa
    76621 ataggagttg taaaaaggca agaagccttt aaacttaata aggagatatt aactaatggt
    76681 aaaattggtt ttcgctcgtc atggtgagtc agaatggaac aaagcaaacc ttttcactgg
    76741 ttgggctgac gttgatttgt ccgaaaaggg aacacagcag gctattgatg ctggaaaatt
    76801 gatcaaggaa gctggtattg catttgatct tgcctttaca tctgtgctta agcgtgctat
    76861 caagacaact aatcttgcac ttgagtattc tgatcagctt tgggtacctg ttgaaaaatc
    76921 atggcgcttg aacgagcgtc actatggtgg cttgactggt aaaaacaagg cagaagcagc
    76981 tgagcaattt ggtgatgagc aggttcatat ctggcgccgt tcatacgatg tgttgcctcc
    77041 tgatatggct aaagatgatg agcattcagc acatactgat cgtcgttacg ctcatcttga
    77101 tcattctgtt attccagatg cagaaaacct gaaggtaaca ctagagcgtg cccttccttt
    77161 ctgggaagat aagattgcac cagccttagt tgatggtaaa aatgtttttg ttggagcaca
    77221 tggtaactct attcgtgccc ttgtcaaaca catcaagcaa ttatcagatg acgagattat
    77281 gaatgtggaa atcccgaact tcccaccgct tgtgtttgaa tttgatgaca agctaaatct
    77341 tactgctgag tactacctcg gtggtgaata atgctgtgag gccagaccta gctctggctt
    77401 tttttgttat gtgataaaaa aggcgtttcc aacagaaatg tgatatgata gttaaaaagt
    77461 ggtaaaagaa gggaatctta tgaaagtaaa ggaacgccga gaagctatta cagataggtt
    77521 aagccaagca caagaagcca tctcagcaac tagcttagcc aaggcattgg gagttagtcg
    77581 tcaggtgatt gtcggagaca ttgccttact tagggcgcag cagcttgaca ttatttcaac
    77641 accaaaggga tatatcctgt caaatgcttt gtttagtcat cactattctg ctagaattgt
    77701 ttgccagcat ggacctgagc agacaaggca ggagttggag ttgatattag cacatgatgg
    77761 cattgtgacc aatgtggagg tagagcaccc tatttatggc atgctgacag caccgcttaa
    77821 cattaaaagc tcagctgata tcaataactt tattgaaaag ctcggagcct ctaaggcaga
    77881 attattgtcg tctttgacag agggtctgca cactcacctt ttgtcctgcc ctgatcagga
    77941 ggcatttgaa gagatcaaga gagatctagc agctgcaggc attctctatg gtgaacaata
    78001 atctgatagc agctggcttc acagggattt agtcttggct tgatagccaa tgtccctctt
    78061 ttgtcgtagg tgatagggac cgcaggacag ctcctagatg ctgaggccaa agtcttgtgg
    78121 ctgggcctca aatgaggtta aaagggaagg aagctgctat ggttatggtg aaagggctag
    78181 atttaccctt acttttttgc taggataatc ttttatgctg ttaggccgca gggcttggtg
    78241 ctgcaatggc tgagatgtgt ctgtcttttg tcttagcttt tggtgcttga gaagggctgg
    78301 gattgagctt atgctgtggt tgttttttga tttgctaggt gtcttgacat ctgtcgcgtt
    78361 tttggttata ctaacgacta gtaaaaggag atattatgac caaaaaacca acacaactga
    78421 ttgcctactc ttctattttg gtggcctttg ccatcttgat tccgatgata atgcccatta
    78481 agcttattat tggcccggct tcctttaccc tagctagtca tctgcccttg tttttagcca
    78541 tatttatatc cattccggta gcgatcttgg tggggatagg aacaggtctg ggctttttgc
    78601 tagcaggatt tcctatgatt attgttatgc gagccttctc acacgtgctt tttgcagcta
    78661 ttgcggcttt tatgctcaaa aggcagccta aatggctgga aacaccgtta agaacctttg
    78721 tttttgggat tatagcaaat gtgattcatg gcctagcaga gtttttagtg gtttatctga
    78781 tgacagcaac agcagcaact gatctttctt atttttggtc aatgctaatg cttgttggct
    78841 ttgggtcttt gctgcatggt atggtggatt tttatctagc cttatttatc tggcgcttct
    78901 taaggcagaa gggtcatcta tcagtgacaa gctaggattt ctgtgagtat ttatgtttta
    78961 gtagccaagg ctgttacagg ctgaggctct tttttctgaa agcgcttgca tttttttgaa
    79021 aaaatgctat actaaagagt gcgtttgtaa atatactaac aaaaggagat gtcatgaaaa
    79081 caccagaaca gatattagcc gcgacgatta cgattggtga gcataaggtt gcaaagcctt
    79141 ttttggctaa ggctatttta ggctttattg gcggtgcgat gattagtttg ggctacttat
    79201 tgtatgttag gattgcagct agtgggctgg agacctttgg cgctttttct agtattttgg
    79261 gtgcttgtgc ctttccgatt gggctgatca ttattttgat ggctggcggt gaattgatca
    79321 caggcaacat gatggcggtg tcggcagcct tttttgcaaa aaagattaag gccaaggact
    79381 tgatggccaa ttggctggtg attacccttt ttaatatttt gggagccttg ttcgttgcct
    79441 ttgtttttgg tcattttctg ggtctgacag ctactggcag ctttaaagaa gaggtcattg
    79501 aggtggccca tgccaagctt gctgcaactc ctctacaggc tattgtttca ggaattggct
    79561 gtaactggtt tgttggcctg gcgctttggc tgtgctatgg cgctagtgat gcgacaggta
    79621 agctccttgg aacctggttt cctgtgatga cctttgttgc ccttggtttt cagcatagtg
    79681 tggccaatgc ctttgttatt ccggcggcta tttttgaggg tggcgccagc tggatcgatt
    79741 ttgcgactaa ttttgctctc gtttatgtgg gcaatgtcct tggcggtgct atctttgtta
    79801 gtctctttta ttacaaggct tatgatcact ctaaggaagc ctgattagtg ctgttatatt
    79861 tttagactgg gagaccttat tctcagtctt atttttatat tttgtgataa aataggaaac
    79921 gacgtttaaa aaggaggagt tgataagcat ctaatatggc atcatggata aaaaagaaaa
    79981 aagcaagcat tcctaggcga attcatctcc tttttttggt gattgttttt ttgtttgttg
    80041 ccctgatttt gagattggca caaatgcaga tttatgagaa ggatttttac aaggcaaagc
    80101 tgacagcgtc aaccgtttac aaagtaaaaa gctctatgcc aaggggaacc atttttgacc
    80161 gtaatgggaa ggttctagtt tctaatcgta tcaaggacgt ggtaacctat acgagaagtc
    80221 ccaaggctag tgctaaggac attaaggctt tggctcatca gctagctgct tatattagct
    80281 atcctgaggc taaagtgaca gtcagagcca aaaaggatta ttatttggca gatccagagg
    80341 cttatgctaa gacggttcaa gccttacccc aaaaggacaa ggtggatcgc tttggtaata
    80401 aattagtcga agcacagata tatcaaaatg cggcagcctc tcttaaggaa acagacttga
    80461 cctattcaga ccaagagcta aaggttattg ctatttttaa ccaaatgaat gcagcagctg
    80521 tttttagcac tgtaaagctc aaaacatcag ccttatctga gcaggatatt gccatcatta
    80581 tggccaataa gtcaaaatta ccaggtattt cagttgggac agactgggag cgtcaggtgg
    80641 aggagacaag ccttgctgct attattggaa gggtctctag tgaggaagcc ggtcttccaa
    80701 aggaagaagc aaaggcttat cttaaaaagg gctattcgct taatgatcgt gttggaacct
    80761 cttatctgga aaagcaatac gaggaggtcc ttcaaggaaa gcatgaaatc agagaaatca
    80821 aaacgagcag atctggtgag gttatttcag ataaaatagt cgaaaagggt cagatggggc
    80881 ggaacctgaa gttgagcgtg ccacttgatt ttcaacaggg cgttgagcag atcttgaatc
    80941 agcacttcca gacagagctc aaaaatggtc aggctgctta ctcagaaggg atctatgctg
    81001 tggcgcttaa ccctaatacg ggagcgattt tagcgatggc aggtctatca cacaatccca
    81061 aaaccggtga gcttcaaaag gacgctttag ggactattac tgatgtgttt acacctgggt
    81121 ctgttgtcaa gggggcgacc ttggctgccg gctggcaggc tggagtgatt caggggaatc
    81181 aggtcttgat tgatcagccg attcaatttg gtggctccca gccgattaat tcttggttta
    81241 ccagcggtca gcaccctatt actgctagtc aggcgctgga atattcatca aatacttaca
    81301 tggttcaggt tgccttaaga atgatggggc aggattacgt gactggtatg accttggcca
    81361 atactggtat gaaggaaacc atgaaaaaat tgcgggcagc ctatgccgaa tttggcatgg
    81421 gagtggcaac tggcgttgat ttgcctggcg aatccagtgg ctacctcata gatcaatata
    81481 atactgcaaa tgttttgaca gaggcctttg gtcagtttga taactataca accatgcaac
    81541 tggcccaata tgtctcaact attgctaatg gcggcagtcg ccttgcgcct cacattgtag
    81601 aaggcattta tcaggataat gaccagtcag gaccaggtaa gctaagtaag gctattgaga
    81661 ctaccttgtt aaacaaggtg cacttagctg ctgatagttt agcgattatt caggacggtt
    81721 tttatcaggt ggtcaatagc ggtagtggct atgctacagg tagggctctt gcaggaggtc
    81781 ctgttaccat tagtgctaaa accggtaccg cagaaaccta tgctaaggat aaaaatggtc
    81841 aggctttatc tacctttaac ttgaatgttg ttgcctatgg tccgagtgct agtcctcaaa
    81901 ttgctgttgc tgtcatgtat cctcatgcga cagactctct agccaaggca catcaatacg
    81961 tggctaagga tatcattaat ttgtacatga agatgtataa aaaccaataa aggagaaacg
    82021 agtgctttac cctataccaa tcgcaaaatt aattgaaagc tattctaaat taccagggat
    82081 tggtgttaaa acagcgacaa gattggcttt ttacaccatt ggaatgtctg atgaggatgt
    82141 gaatgatttt gccaaaaatt tattagcagc taagcgagaa ttaacctatt gctctatctg
    82201 tggcaatttg acagatgatg atccctgcca tatttgcaca gatagcagtc gggataaaga
    82261 gatcatttta gttgttgagg attccaagga cgtttctgcc atggaaaaaa ttcaagaata
    82321 tcatggctat taccatgtgc tgcatggctt gatttctccc atgaatgggg ttggcccaga
    82381 tgacatcaat ctaaagagcc taatcacgcg tttgatggct ggagaggcaa cagaggtcat
    82441 tgttgcaacg aatgccacag cagatggaga ggcgactgcg atgtacatct cacgtctcct
    82501 aaagcctgct ggtatcaagg tgacgcgatt ggctagaggc ttggcagtag gatcagacat
    82561 tgaatatgct gatgaggtaa ccctgctgcg agcgattgaa aatcggacag aattatagct
    82621 tagcccattt tcagctctct gtcattagcc cttatgccat gtgataaggc cataaaggaa
    82681 ggcagatttt gtcagagtct tttgaaaagc aagctcgttt ttgttataat aagtggtagt
    82741 ctaattcaga tagggaaggt tatcaatgtc taaacaaacc ttaattttat tatacggagg
    82801 gcgttcggca gagcgtgaag tatcagtgct ttcagctgag agcgtgatga gagcagttga
    82861 ttacaccaaa ttttttgtta aaacctattt tatcagccag acaggtcagt ttatcaagac
    82921 acaggaattc tctagtcggc cgaccttaac agaaaggctg atgaccaacg acactattag
    82981 gctagagcag cagataaggc ctagtgatat ctacgaggag ggggctgttg tttttccagt
    83041 cttgcatggc cctatgggag aggacggttc tattcaaggc tttttagagg tgctaaaaat
    83101 gccttatgtg ggaactaata tcctctcatc aagtgttgca atggataaga ttaccaccaa
    83161 aagggtccta gagtcagctg gtatcccaca ggttgcttat accgtttata ttgaggggca
    83221 ggatttagac aggtgtctgg cagagactga ggcagtctta agctaccctg tgtttgttaa
    83281 gccggccaat atgggctcat ctgttggtat ttctaaggca gaatcagagg aggagttgcg
    83341 tgcagctatc ctgttggcct tgacgtatga cagtcgtatc ctgattgagc aaggggtttt
    83401 ggcaagagag attgaggttg gactgcttgg taataccgat gtcaaatcaa cccttccagg
    83461 agaggtagtc aagaatgttg acttttatga ttatcaggcc aaatacattg ataatgagat
    83521 cacaatggct attccggcag ctattgacga atcagctatg acaagcatgc gtacctacgc
    83581 agaaacagcc tttaaggcta ttggtgcttg tggcctgtcg cgttgtgatt tcttccttgg
    83641 tcaggacggt cagatctacc tcaatgaatt aaataccatg cctggcttta cgcagtggtc
    83701 catgtatccc ttgctctggg agcatatggg actgagctat gctgagctta ttgaggagct
    83761 agtcagatta gcacaggaaa tgtttgaaaa gcgtgaaggg catttaatat aagagacaaa
    83821 ggacggaagg agatatagca atcctctgtc ctttcgtttg gcctgattgg tagcgttttt
    83881 tggtcagaag cctttaaagc cctatcgtct acggttggct gtgccagctt tagcctgtct
    83941 atgaaggatc agcctgtagg cataaagtga aatagaaaga atattcctaa tatgttatgc
    84001 tata
//
LOCUS       DARYLD010000002        70485 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYLD010000002 DARYLD010000000
VERSION     DARYLD010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70485
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(713..799)
                     /locus_tag="TU651_000081"
     tRNA            complement(713..799)
                     /locus_tag="TU651_000081"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(763..765),aa:Ser,seq:gga)
     gene            complement(859..1494)
                     /gene="trmB"
                     /locus_tag="TU651_000082"
     CDS             complement(859..1494)
                     /gene="trmB"
                     /locus_tag="TU651_000082"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL0896127.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            complement(1494..2285)
                     /locus_tag="TU651_000083"
     CDS             complement(1494..2285)
                     /locus_tag="TU651_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL0896128.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            complement(2348..3382)
                     /locus_tag="TU651_000084"
     CDS             complement(2348..3382)
                     /locus_tag="TU651_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896129.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            complement(3386..4111)
                     /locus_tag="TU651_000085"
     CDS             complement(3386..4111)
                     /locus_tag="TU651_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896130.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            4648..5091
                     /locus_tag="TU651_000086"
     CDS             4648..5091
                     /locus_tag="TU651_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896131.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            5544..5963
                     /locus_tag="TU651_000087"
     CDS             5544..5963
                     /locus_tag="TU651_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL0896132.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            5960..6256
                     /locus_tag="TU651_000088"
     CDS             5960..6256
                     /locus_tag="TU651_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL0896133.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(6426..7688)
                     /locus_tag="TU651_000089"
     CDS             complement(6426..7688)
                     /locus_tag="TU651_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0896134.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(7689..8216)
                     /locus_tag="TU651_000090"
     CDS             complement(7689..8216)
                     /locus_tag="TU651_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896135.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            complement(8209..8652)
                     /gene="tsaE"
                     /locus_tag="TU651_000091"
     CDS             complement(8209..8652)
                     /gene="tsaE"
                     /locus_tag="TU651_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL0896136.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            complement(9018..10478)
                     /locus_tag="TU651_000092"
     CDS             complement(9018..10478)
                     /locus_tag="TU651_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL0896137.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            10737..11548
                     /locus_tag="TU651_000093"
                     /pseudo
     CDS             10737..11548
                     /locus_tag="TU651_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            11900..12892
                     /gene="manX"
                     /locus_tag="TU651_000094"
     CDS             11900..12892
                     /gene="manX"
                     /locus_tag="TU651_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL0896138.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
     gene            13063..13872
                     /locus_tag="TU651_000095"
     CDS             13063..13872
                     /locus_tag="TU651_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL0896139.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            13888..14799
                     /locus_tag="TU651_000096"
     CDS             13888..14799
                     /locus_tag="TU651_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0896140.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            14933..15316
                     /locus_tag="TU651_000097"
     CDS             14933..15316
                     /locus_tag="TU651_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL0896141.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(15637..16689)
                     /locus_tag="TU651_000098"
     CDS             complement(15637..16689)
                     /locus_tag="TU651_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL0896142.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            17289..18566
                     /gene="serS"
                     /locus_tag="TU651_000099"
     CDS             17289..18566
                     /gene="serS"
                     /locus_tag="TU651_000099"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL0896143.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            complement(18798..19568)
                     /locus_tag="TU651_000100"
     CDS             complement(18798..19568)
                     /locus_tag="TU651_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL0896144.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRVIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(19565..20431)
                     /locus_tag="TU651_000101"
     CDS             complement(19565..20431)
                     /locus_tag="TU651_000101"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL0896145.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            complement(20440..21804)
                     /gene="accC"
                     /locus_tag="TU651_000102"
     CDS             complement(20440..21804)
                     /gene="accC"
                     /locus_tag="TU651_000102"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL0896146.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            complement(21838..22260)
                     /gene="fabZ"
                     /locus_tag="TU651_000103"
     CDS             complement(21838..22260)
                     /gene="fabZ"
                     /locus_tag="TU651_000103"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL0896147.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            complement(22257..22730)
                     /locus_tag="TU651_000104"
     CDS             complement(22257..22730)
                     /locus_tag="TU651_000104"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL0896148.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            complement(22732..23964)
                     /gene="fabF"
                     /locus_tag="TU651_000105"
     CDS             complement(22732..23964)
                     /gene="fabF"
                     /locus_tag="TU651_000105"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL0896149.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            complement(23980..24714)
                     /gene="fabG"
                     /locus_tag="TU651_000106"
     CDS             complement(23980..24714)
                     /gene="fabG"
                     /locus_tag="TU651_000106"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL0896150.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            complement(24731..25651)
                     /gene="fabD"
                     /locus_tag="TU651_000107"
     CDS             complement(24731..25651)
                     /gene="fabD"
                     /locus_tag="TU651_000107"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL0896151.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            complement(25664..26650)
                     /gene="fabK"
                     /locus_tag="TU651_000108"
     CDS             complement(25664..26650)
                     /gene="fabK"
                     /locus_tag="TU651_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL0896152.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            complement(26845..27069)
                     /locus_tag="TU651_000109"
     CDS             complement(26845..27069)
                     /locus_tag="TU651_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0896153.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            complement(27127..28101)
                     /locus_tag="TU651_000110"
     CDS             complement(27127..28101)
                     /locus_tag="TU651_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL0896154.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            complement(28101..28535)
                     /locus_tag="TU651_000111"
     CDS             complement(28101..28535)
                     /locus_tag="TU651_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0896155.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            complement(28615..29406)
                     /locus_tag="TU651_000112"
     CDS             complement(28615..29406)
                     /locus_tag="TU651_000112"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL0896156.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            complement(29726..30862)
                     /gene="dnaJ"
                     /locus_tag="TU651_000113"
     CDS             complement(29726..30862)
                     /gene="dnaJ"
                     /locus_tag="TU651_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL0896157.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            complement(31019..32848)
                     /gene="dnaK"
                     /locus_tag="TU651_000114"
     CDS             complement(31019..32848)
                     /gene="dnaK"
                     /locus_tag="TU651_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL0896158.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            complement(33253..33822)
                     /gene="grpE"
                     /locus_tag="TU651_000115"
     CDS             complement(33253..33822)
                     /gene="grpE"
                     /locus_tag="TU651_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL0896159.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            complement(33867..34901)
                     /gene="hrcA"
                     /locus_tag="TU651_000116"
     CDS             complement(33867..34901)
                     /gene="hrcA"
                     /locus_tag="TU651_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL0896160.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            complement(35351..35923)
                     /locus_tag="TU651_000117"
     CDS             complement(35351..35923)
                     /locus_tag="TU651_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0896161.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            complement(35920..36663)
                     /locus_tag="TU651_000118"
     CDS             complement(35920..36663)
                     /locus_tag="TU651_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL0896162.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            complement(36653..37360)
                     /locus_tag="TU651_000119"
     CDS             complement(36653..37360)
                     /locus_tag="TU651_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0896163.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            complement(37435..38772)
                     /locus_tag="TU651_000120"
     CDS             complement(37435..38772)
                     /locus_tag="TU651_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL0896164.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            complement(38787..39053)
                     /locus_tag="TU651_000121"
     CDS             complement(38787..39053)
                     /locus_tag="TU651_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL0896165.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            complement(39317..40432)
                     /locus_tag="TU651_000122"
     CDS             complement(39317..40432)
                     /locus_tag="TU651_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL0896166.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
     gene            complement(40629..40868)
                     /locus_tag="TU651_000123"
     CDS             complement(40629..40868)
                     /locus_tag="TU651_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0896167.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            complement(40919..41863)
                     /locus_tag="TU651_000124"
     CDS             complement(40919..41863)
                     /locus_tag="TU651_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL0896168.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            complement(42092..43531)
                     /gene="gatB"
                     /locus_tag="TU651_000125"
     CDS             complement(42092..43531)
                     /gene="gatB"
                     /locus_tag="TU651_000125"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL0896169.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            complement(43531..44997)
                     /gene="gatA"
                     /locus_tag="TU651_000126"
     CDS             complement(43531..44997)
                     /gene="gatA"
                     /locus_tag="TU651_000126"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL0896170.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            complement(44997..45299)
                     /gene="gatC"
                     /locus_tag="TU651_000127"
     CDS             complement(44997..45299)
                     /gene="gatC"
                     /locus_tag="TU651_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL0896171.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            complement(45773..46330)
                     /locus_tag="TU651_000128"
     CDS             complement(45773..46330)
                     /locus_tag="TU651_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL0896172.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            complement(46947..47729)
                     /gene="codY"
                     /locus_tag="TU651_000129"
     CDS             complement(46947..47729)
                     /gene="codY"
                     /locus_tag="TU651_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL0896173.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            complement(47901..49115)
                     /locus_tag="TU651_000130"
     CDS             complement(47901..49115)
                     /locus_tag="TU651_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0896174.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            49402..49854
                     /locus_tag="TU651_000131"
     CDS             49402..49854
                     /locus_tag="TU651_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0896175.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQEAKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIP
                     DKEEVDLIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
     gene            complement(50140..51528)
                     /locus_tag="TU651_000132"
     CDS             complement(50140..51528)
                     /locus_tag="TU651_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0896176.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            51600..52565
                     /locus_tag="TU651_000133"
     CDS             51600..52565
                     /locus_tag="TU651_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL0896177.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            complement(52685..54700)
                     /gene="recG"
                     /locus_tag="TU651_000134"
     CDS             complement(52685..54700)
                     /gene="recG"
                     /locus_tag="TU651_000134"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL0896178.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(55064..56518)
                     /locus_tag="TU651_000135"
     CDS             complement(55064..56518)
                     /locus_tag="TU651_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896179.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            complement(56455..57135)
                     /locus_tag="TU651_000136"
     CDS             complement(56455..57135)
                     /locus_tag="TU651_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0896180.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            complement(57132..57725)
                     /locus_tag="TU651_000137"
     CDS             complement(57132..57725)
                     /locus_tag="TU651_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0896181.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            complement(57706..59388)
                     /locus_tag="TU651_000138"
     CDS             complement(57706..59388)
                     /locus_tag="TU651_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896182.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            complement(59381..61144)
                     /locus_tag="TU651_000139"
     CDS             complement(59381..61144)
                     /locus_tag="TU651_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL0896183.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            complement(61190..61972)
                     /locus_tag="TU651_000140"
     CDS             complement(61190..61972)
                     /locus_tag="TU651_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896184.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            complement(61969..62991)
                     /locus_tag="TU651_000141"
     CDS             complement(61969..62991)
                     /locus_tag="TU651_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0896185.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            complement(62993..63877)
                     /gene="isdE"
                     /locus_tag="TU651_000142"
     CDS             complement(62993..63877)
                     /gene="isdE"
                     /locus_tag="TU651_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL0896186.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            complement(63861..64766)
                     /locus_tag="TU651_000143"
     CDS             complement(63861..64766)
                     /locus_tag="TU651_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL0896187.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            complement(64995..68746)
                     /locus_tag="TU651_000144"
                     /pseudo
     CDS             complement(64995..68746)
                     /locus_tag="TU651_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            complement(68948..70363)
                     /locus_tag="TU651_000145"
     CDS             complement(68948..70363)
                     /locus_tag="TU651_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0896188.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
BASE COUNT        20390 a        16887 c        13787 g        19421 t
ORIGIN      
        1 aatctccctc attatatcat aaaaacgatt tcaaaaacag acttgtattt caagtgacat
       61 ttgatatact tgaagatggg aatactgctt gagtggaggc attgtaggtc tagttcaacg
      121 taaagcagca gctgaaatcg caaaactaat acttaaagtg gggatcaaga atgtagcccc
      181 tgctgcagct gcagcatcat taatttggag ctttggaaga tgcatgtggt tttaatgtca
      241 aaaagatata gtatttgtat aacatttctt gttattattt cgcgattcgt ttggtttgcc
      301 cttacaggaa gaagtccttt ttatgacttt attgggacta tatttttagg agtagtggtt
      361 ttactaatta gtcaaaaagt attgaaaaaa ttaaagtgat aaaattatta acccgacaat
      421 agcgaagcag aatgtgatat tattgatatg ttccataaga tactttctaa tgagattgtt
      481 agtgcttctc atgataagtc ttatgggact tttttgtact caaaaagccc tatcatttcc
      541 atactggata aatccactac agaaatgata gagcctaaaa tatatgttca ccaattggat
      601 aagttaaaag aaaaaaatga ccatcaggtc aaaagcattt ttcaaaatct caaatttgac
      661 gggtgaaaaa caggcgaaga ctccgaaacc cttgatatac caataggata aaaggagagg
      721 aggggattcg aacccccgag ccccgttaag gactacacgc tttccaagcg tgcgcactcg
      781 gccactatgc gacctctcca agtaaaaggc tgatcaactc aacctcagta gtgtatcata
      841 tttttgtcaa aatagctact agaatgttgc ttctaggcgg taaataatct gtcccttttt
      901 agcaaatcta gcctcatact cagtcatcac atttccttga taatcactag catgtaaatc
      961 cagccagacc tgcttgaggg tcataccgta ctgtgaaaag ctcgctaggc tatactcaaa
     1021 taagccacga ttatctgttt taaaatgaat ttcaccattt tccggcaaaa tctgcttata
     1081 agtgtctaaa aaggatttgt aggttagtcg acgcttttca tgcctgcttt tgggccaagg
     1141 atctgaaaaa ttcaaataca tcatatcaac ctcaccggca tcgaaataat tggtcaggct
     1201 tgacccatca acccgcaaga gcctaacatt aggagcctga gaggctagga ccttatctaa
     1261 agcatagctt agcactgata gctgaatgtc aatgccaata tagttgatct ctgggttttt
     1321 caacgccata cctgtgataa aggctccctt gcctgagcca acctcaatat ggatcggatg
     1381 atcattacca aagacctcac accagcgccc cttagcagcc tccggctcta aaatgacata
     1441 gtgaggattg ttttccaagt gctcctgcgc accctttcgt tttctaactc gcattatttc
     1501 tttctaaaca tttctctaaa ttttctaaga gcgtaaatct cttgattgac atgctccata
     1561 tctctcttat caaagcacct taaaatctga gttagataag agaattgagc ataccaaata
     1621 atcttttgca tgaccttatc attattttta tagccataat aggatagcca gtctgcccat
     1681 cgcgaccgag gaatatagtg gcttagcaaa taagccacat catacattcg atctgttagg
     1741 cgcacacaat cccagtccac caaaaaaatc atgccactgg tggtaatcac ccagttgcta
     1801 tgcttgatat caccatgtac aatcgtggcc acctcagagc gaaattcagg taggctgcgc
     1861 tttagctcct tgacgatagc ctgtaaataa gaattctgtt gaatttgcaa aggtgcattt
     1921 tgctcaaagt ctactaaaag gtcataagga ttttcaattt tatagttgag ctgaagcaat
     1981 tgattaacca actgcttgga cttgtggagg cgcagcagaa tatggacgat ttgcttactg
     2041 ttcatatcct ctctagtcag agtacgacca ttgagccact cttgagcact catcatatcg
     2101 ccattcccca tacgctttgc ccaaagcaat tgtggggcaa tctgttcctt tgctaaggca
     2161 ggtaggattg gtgttgtatt aagcttgata aagacgcttt cgccatttgg ataggtccct
     2221 ttgtaggctt tgccactttt tccgcgcaag ggagtcaata caagatcctg ttcggttgtt
     2281 gtcaccttat cccctccttt tctatcttct gtaaccagtt atccctattt tacttgtttt
     2341 aaaggactta gtcaatcatc ttctttaact tgtacggtaa gtaaagaaga tttaataatc
     2401 ccatcgccac aatcaacaca agagcatttt gccaagaacg gcagagcaca agattgacga
     2461 taagcatcaa accacttaat tgcctcaaca aagaaagtag attcctttgc ttatgctgtg
     2521 gtttagtcgg gtaaagccca ctcatataat ggtaatcata atgatgataa agtgataata
     2581 actgaaaaag acttagataa tgaaagacca aggccaagcc tactgctaaa taagggttgg
     2641 aaataaaggc aagtgacaag caactaagca acaacagacg taaccataac cctagataat
     2701 cagagctgcg taaaaatgct cttaaatata ggtttgtcca aaccttttta ctatctgcct
     2761 tgataagctt aagtatagga ttcaagtaag gcctttcctt aaccttggtt gagattcctt
     2821 taacatttgt aaacaaagca taaaacttta aaatggcctg ctggcgatct gcctcaaaag
     2881 caatcgcttt ttcccaatca agccccttgg agctcaaaaa gcttgccacc ttacgcttta
     2941 acagtaagcg cttagccagc accaaaacac caagcaatag cacaaaggca agcaaggaaa
     3001 caccaagcct ttgaaacaaa ggaaataaag gtaacagcaa gaccgtttga aggctagacc
     3061 aaagaataaa ggacaagcgc tctgctgacc tgatatgggc aataacctct gcctccttgg
     3121 tcagcaaaaa atgctgatca gccttttcaa gataggtagc aactgacccc agattaagca
     3181 aaaacaagac agcaatcaac aaacctagct gaatcggtag aggattagca ggaaaatgct
     3241 tgagtagttg actgtactga aaaagaataa agcccaaaag aaacagcaag acaagaacaa
     3301 aatgatcatt aaagacataa ggcagatact tggtatgctt gtgctgaaac tcctgacgac
     3361 gcttacgaaa taatgccttc atagcttacc cctcttttgt cagcgctagg taaatgtcat
     3421 taagactagc tgaagcatct ccaaagactg cctgcaaatc cgccagagtc ccttgtgcac
     3481 gcacctgtcc ctgatgcaat atcacaaaac ggtcacacat tttttctgcc gaatccagca
     3541 catgggtact cattagaatt gacttgccct ttgccttttc aacctctaaa gccttaatca
     3601 aatcagcaat tgctaagggg tcaagcccca aaaagggctc atcaagaata aaaagactag
     3661 ggtcaatgac aaaagcgcaa ataatcataa ccttttgctt cattccctta gaaaaatgca
     3721 ccggaaacca atccagctta tccgtcaaac gaaacagctc taagaagggc tcagctcgct
     3781 tatgtgccag ctccacatca atatcatagg ccatagctac cgtattgata tgctctgcta
     3841 aggtcagctc ctcatacagg cttggtgttt ctgggataaa gccaattttc ttgcgataat
     3901 cagcttcatg ctccgccaag gttaagccat caatggaaat ccttccctta tatggcttta
     3961 aaaacccaat aatttcatta atcgttgttg acttaccagc accatttaga ccaataagcc
     4021 ctactagctc tccatttccg acagaaaagc taatatcctt caaaactgga atattaaggt
     4081 agcctccagt gacattctca atgtttaaca tatcatttct ttctaatatc taatctattg
     4141 tagctttgca tactagcttc cctagatgac aggttattag cctagacaga taggacttac
     4201 taggcaatgc tttgtcatca tcagcctatc cagcgctttg aagcactgat aagaccaatt
     4261 agcttgaccc tacttaagaa agctggggca gctaatacta agggtacact tatattagct
     4321 attataacaa atttctgcac agagcgttaa ctgttttgat caatgctccc atcagctaaa
     4381 aacgctgagt gaatctgaag tctattttaa gatcatcaag aaaaaggcct agctataaaa
     4441 acagaggcta tattagcttg atctatcagt cctaaccatc tatcacatca tattcgaatg
     4501 acctggtgat cctaaatagc agctcatcta aggcgtcatc taaaaaatca tgataatatt
     4561 atcttattgt attgaatttt taataatata atgttatcgt taacatgtaa ataagtgttg
     4621 cgtctttaat gacaaaggag gtatgttatg aatttgtcac gctttttaac atttggtttg
     4681 gtatcacttt cagcactttc aatttcaggc ctagtccaaa cagaggctaa ggctaacgaa
     4741 tggcagacta tctttgaaaa gccacaggag gtggttatca cagatggctg gcaaactatc
     4801 tctgaaaagc ctcaggaagt aagcacggct aacgaatggc aggtcagctc tgaagaagct
     4861 caagagtctg ttcctgataa attctcacaa aacgaagacc ctagcctatg ggctgttcct
     4921 gataaattct cacaaaacga ggaccctagc ctatgggccg ttcctgataa attctcacaa
     4981 aacgaggacc ctagcctatg ggccgttcct gataaattct cacaaaatga ggaccctagc
     5041 ctatgggctg ttcctgataa attctcgcaa aacgaggacc ctagcctgta gtaaagccat
     5101 ccgcactcga ttgaagataa ggcctatgtt gctgacgctt caatcttttt ttgttctaaa
     5161 agctttctca gccttaactg tcaagaagtt ccagcacctc atactctctg aaactcttgt
     5221 ccttacaaat attgtgccat gtcactaccg tacgatagtg cgcaaatgca cacctttgac
     5281 ggacctagct tgcagcaagt agcaggctta gttatgtgct taaccataat tgcttagtcc
     5341 attatcatga ttcaaaaggc tttgctagtc atgtggtcga taaccattag caccagctat
     5401 aaacaattgc aatatagacc agtacatgct aagataacta tagtatgaga tagctatggt
     5461 cactgagcaa ctactgattt cttattctaa aattattcaa ctactgattt gagccattgc
     5521 tacgcagacg aaaggattat cacatggaaa attgtatctt ttgcagcatt attagcggtg
     5581 agattccctc ctccaaggtt tatgaggatg agcaggtact cgcttttttg gatatttcgc
     5641 aaacaacagc gggtcatacc ctcttgattc ctaaaaagca tgtccgaaat atcctagcaa
     5701 tggacgccga gacagctagc cagacctttg aacgattacc taaaatcgct cgcgccattc
     5761 aaaaagcaac aggtgctact gcaatgaaca ttattaataa taatgaagag ctagctggtc
     5821 agactgtttt tcacgcgcat gtgcacctcg ttcctcgcta cagccaagaa gacgggatcg
     5881 ctattcagta tacaacacat gagcctgact tcccagccct agcagccttg gcacaacaaa
     5941 ttagtcagga gattagccaa tgactctaaa aacaatgacc acaattggtc tcacatccgt
     6001 tttagcctac caagtgtatc gtaaacgtca tcaaatcaaa gaaactctag tagccatgca
     6061 aacctctaag aaggctatcc aggccgatgt tgataggatt aaggcaaatc tcgccatcat
     6121 tcaaaaggag gctcgaacgc ttcaagcagc aggaacagaa ttagcctaca aatggcaggc
     6181 ctttaaccaa gaagctcagg cccatctgac tgaaatccaa caacgtatga gcaagtacca
     6241 gcaggaaacc ccataagcct aagcagacta ccaagcctca aggtgacaaa aaagggctct
     6301 atcgtttctg tagtggacaa gtccgctata gggattatgg gctctttttg tatgtacaaa
     6361 aaagacgaag aaatcactca caggatcaag ccttgatgag atttcttcgt ttttttggct
     6421 gtaccctaag gcgctgctgg cgtaccagtg gttgcaccac ttgattgctg ctctgctggt
     6481 gagtctgctt gagggctagg agtcacatta gctgctcctg actcttgtgt accagctgtt
     6541 gtgtcctgat agctgctgct agaggacgtc tctgaggaat aggttgagta ctgggtagat
     6601 gagtctgtat aggccggtag gctacctgaa ttgtaataat agctgctatc ctgagtagac
     6661 tgagttttta acgagccata aaggttttcg taaactgtgg cagtcgtttt tagctgacta
     6721 agcttttcaa ggcctaattc agcacgaatg cgattttgga tttctaaaag atgatctgag
     6781 gtcacaattt gataggagcc gccatctgac aaggtcgctc cctcaccctt tagctgatag
     6841 gttttgatat ttttaagggc gtctgtatag cctaaaagat taggaatggt tcgtgatgat
     6901 atttcaatgt tggtttgcat attaccacta acagctgaca agatctttcg gtaggagctg
     6961 atactgttaa gggcaagaat ctttttcagc accttttgaa taacctcgcg ctgacgcttc
     7021 tgccgaccgt agtctccctc tggatcatca tagcgcattc gagcatagac caaggcctgc
     7081 tctccattta tcttgtgagt tcctggtgca acggtagcct gatactcagg ctcattatct
     7141 gcaatagaga taggaaagtc aaattcattg gtaacagtaa tgccaccaac agcattaacc
     7201 aaatcaatga gcccttgcat gttaatctga acgtatttgt caatcgtgat attcagcaag
     7261 tcctgaacgg tcatgatagc catttgggca ccaccagctg cataagcagc attcagctta
     7321 gcttctgctc cattcatctc attatcattt ggacctgaca aagtgatgag aatgtctctt
     7381 tctaagcttg tcatggttgt ctttttggtc ttagggttaa tcgtaaccag aatcatagaa
     7441 tcactatttc cttgccaggt agaggttctg tgagacgatc ctgtgtcaac tcccatcaat
     7501 agaattgaaa agggctctgt ctgttgaatg gcatcacttt ttttggagga cgttgcaaaa
     7561 tccttaaagg tctttgacaa ttctccagtt gaaaaggtat aggcattggt taggtaaact
     7621 cccatagccc ccaaggtcaa cagcacaata gctgtcagca ttaaaaagat tttttttcca
     7681 attttcatct attcacgttc cagatattta cgcataaggt aaacatcctg atagtctcca
     7741 tttcttgatt tgacgtcctt tcttttgacg ccctctattt taaagccata tttctcataa
     7801 atatgatagg cacaagtatt tcgagcctga acctccagct ccaaagcaca aagctgcttt
     7861 gtttctctgg cccaatcaag ggtagtctcc atcaaaagct gtcctaggcc atgattgcgg
     7921 tagggtttca agaccagcat aaagcaatcg ccaacatagc tagtctcacg atatgctttg
     7981 ccagctatat ttagcagacc agctaatata tctcccacct ttagcaaaag gcaaatatct
     8041 gtcaaagact cctgactagc ctctagaaaa cactcaagca cctctacggt agcagctatg
     8101 acgtcctcag tccctgtgat aaaatctgtc tcatcagcag cttctttaat tagagtgatc
     8161 aaagctgacg catctgaggc cttggcctct tcgattgtca ccacctgctc agacatgctt
     8221 aagctcctca agaagtgcct ctgatcgatg accatgtgct agataatcaa cctgccggcc
     8281 tgtttctgtt tttgttatta aaatttcaag gtagtcatgc agggttccct tggctaaaag
     8341 ctcgccccac tcaatcacag taaccccacc accaaagata aaatcatcta aatcaataga
     8401 gtccggatca tcaccaatcc gataaacatc taaatgatac aagggtagtc ttccctcata
     8461 ttctcgagcg atagtatagg ttgggctttt aatcatctga tcaatcccca aacccttagc
     8521 aacccccttg gtcagcgttg ttttaccagc acctaagtca ccagtcaaga caagcacatc
     8581 tcctgccttt agctgtctac caatgccttg cccgtaagcg attaattcat tctcattttt
     8641 gctataaaac ataaggctat tataacagaa aaaaaacggt cttccaagcc taagccagcc
     8701 tgtcagcaaa atattctagg ctcgtcagtc ctcatataat gtcgtcaaag ctcaatcagc
     8761 tttaacatct cataaatcaa aagagccagc agcaaatcac atggacctaa catcatggca
     8821 ttctgctgtg atagccaggg ctgaatgctc tagaaatcaa cccgcagctc taaaacctta
     8881 agacttagcc taaatatagg actaggaaaa ggtggcaatg cctatgagct tagaaagtcc
     8941 atagtcccag tccaaacggt aatccctgtc tttattgtcc cagcaaaaaa gaggcaccta
     9001 agtacctcat tagtcgttta caataacgct aaaatgataa aattcaaaac aaataagaag
     9061 gttgctcccc aaagaatcgg gtgaatctcc ttggttttgc ccttcacaag cttcaccaag
     9121 caatagaaaa taaaggagcc agccacaccg tatgaaatag agtagcaaag tgccataaag
     9181 aaagcagcaa agaaggacgg tagggcaacg tcaaagtcgc tccaatcaac atcaaggaag
     9241 gacgatacca tcataacccc gacaatgatt aaggctggtg cagtcgcagc ggctggaaca
     9301 attcccacga tcggcagcag taaaacagat aagacaaagc agacagcagt tgatacagct
     9361 gttagacctg tacgtcctcc ctctgcaata ccagcagcag actcaacgta ggttgtggta
     9421 tttgaggtgc caaataaagc tccgattgaa gtaccaatag cgtcagcaaa gagcgcacgg
     9481 tccatttttg agctaaagcc agagctgttt tccaaagctc tctcatcctc ctcagagaaa
     9541 atccctgttc gacgaccagt cccaacaaaa gttccaatcg tatcaaaggt atcagataga
     9601 ctaaaggcaa agatcgtcat taaaacaagc ggcaagcgac ttgaatcact aaacagtgac
     9661 gccatgccac caaaggcagc caagaatgtt gtccctaatt cagcaaaggc tgagctgatg
     9721 tgattgtctg caaaattaac agcagaaaga tcaaccactc caataggaat accggctaaa
     9781 gttgtaactg taataccaat taggatggct ccacgaacgt tcttaagcac aagcactgct
     9841 gttagcagca gaccaaaaac tgctagcaaa acactcggat cggtgaaggt tgaaatagct
     9901 ggaaccacac caccattagc attaacagag aagacgccat tagcaaatgt ttcagcagtt
     9961 gccttagctg gctcaacacc atttacagta acaatctcag cagatgatag cgaaaaggtg
    10021 atcaggttag catttttaaa acctagataa gcaacaaaga ctccaatacc tccgccaata
    10081 gcatgctgca ggcttactgg aatagccttg ataatgctct tgcgaagctt tgtgacagtg
    10141 ataaagatat taaacagacc acaaagaaag acaatagcca aggcctcctg ccaagaaaat
    10201 cctaagctaa aaacaacagt gtaagtaaag aaagcattaa gtcccatacc aggagccaat
    10261 gcgtaaggca cattagcaaa caaacccatg atcaaggtag agatagcagc tgcgatgatg
    10321 gtcgctaaaa acaccgcttg cgacggcata cccgctgcac tcaaaatact tgggttaaca
    10381 aataagatat atgacatcgc aaaaaaagtc gtcacaccag ccatcagctc tgttgaaacc
    10441 gtcgtgccat tttcttttaa cttaaaaaac ttttccattt gaatggagtc tccttattga
    10501 taggcaaaat caaaaaagcc cttatctcat cagataagct ttttctctta aaaccaaatg
    10561 attattatcg tttttacgaa cgatatattc atcgtaacat tttatcgttc tattttcaat
    10621 agcttttttc gtttatttgc catgatcgtt caaaatttaa cagccttttt ttctattaac
    10681 cgtccaagca gcaattttct cttccactga tcctaaaatt tgttataatc tagtgtatga
    10741 ctaaaaaact aattgctatt gatttagacg ggactttatt gcatcacgac aataccatct
    10801 ctacctatac tcaaaaaacc attaaggccg tccaagctaa gggacatgag gtcatcatct
    10861 cgacaggacg tccttatcgt atggctattg actactacct tcagctagag ctaaagacac
    10921 ctatgattag ctttaatggc tctttgaccc acctacctga gcaaagatgg aaatacgagc
    10981 ataatgtgac tcttgataag gcataccttc tcaaactcct agcagtgcag gaggacttcc
    11041 agatggactt tattgctagt gagtaccgaa aagccttcta cattaccatg aataggcctg
    11101 agagcattga ccccaacctt tttggtttga ggccatcaca ccagatatgg ctttacagat
    11161 cgacaaaatc acgcaggatc caaatgctct tctcatgcaa acgcatcatg aggataagta
    11221 tgccctagcc aaggccatgc gcgccttctt caaggacgaa attgaggtgg actcttgggg
    11281 tggtccctta aatatccttg agatgtcccc caaaaacatt aataaggcct ataccttaaa
    11341 atacctgctt agcatttaca acaaggagcc taaggattta atcgcctttg gtgatgagca
    11401 taacgacaca gaaatgctgg cctttgccgg aaccggctat gccatgaaaa atgccagccc
    11461 tgtgctgctg ccctttgccg accagcagct agcttactct aacgaagagg acggggtcgc
    11521 cagaaaacta gaagagcttt tcttgtgaaa gcaaacgaaa ccattgtttt tcagaaaacg
    11581 atggttttct taatgccgtt tccgtcaatt gatgaaagaa tttctaatat tttcgttatt
    11641 tttcagcata ttttcttttt tatgcggcat aaaaatccct ttattatcaa tattctactt
    11701 attcggcagc gcattatgaa aattttttca tatttcgtaa gatttttccg aaagggcttg
    11761 atttttaagt gaaaacgttt taaaatagag acgttcttga atttcgttca agtgaaaaag
    11821 aattgccaaa tgctatttgg aaggagatta ttcttcttca tttcaacgaa aaatatttta
    11881 ataaggagga agaacaagaa tgggtatcgg tattattatt gccagccatg gtaaatttgc
    11941 tgaaggtatt catcaatctg gttctatgat ttttggtgaa caagagaaag ttcaagttgt
    12001 gactttcatg ccaaatgaag gaccagatga cttgtatgga cacttcaaca atgctatcgc
    12061 acaatttgat gctgatgatg aaatccttgt actagctgac ctttggagtg gttctccatt
    12121 taatcaggct agtcgtgtgg caggagaaaa tcctgatcgc aaaatggcta tcatcactgg
    12181 tctaaatttg ccaatgctta ttcaagccta tactgagcgt ttgatggacg ccaatgcagg
    12241 tgttgaacaa gtagccgcaa acatcattaa agaatctaag gacggtatta aagcccttcc
    12301 tgaagagctc aatccagttg aggaggcttc tacagctaat ggtggtggtc aagcgcttca
    12361 aggagctatt cctaagggaa ctgtcattgg agatggtaag ctaaaaatca accttgctcg
    12421 tattgacact cgtcttcttc atggtcaggt agcaactgca tggacaccag cttctaaggc
    12481 tgatcgtatt attgtagcgt cagattctgt ggctaaggac gagcttcgta agcaattgat
    12541 caagcaggcg gctcctggtg gggttaaggc taatgttgtt ccgatcaata aattgattga
    12601 ggcttctaag gacccacgct ttggcaacac tcacgctctt atcctgtttg aaactgttca
    12661 ggacgccctt cgtgcgattg aaggcggcgt tgagatcaaa gagctgaacg ttggatcaat
    12721 agcgcattca acaggtaaaa caatggttaa caacgtattg tctatggaca aggatgacgt
    12781 tgctgccttt gaaaaattac gtgatctagg tgtttcattt gacgttcgta aggtgccaaa
    12841 tgattctaag aaaaacctat ttgagcttat ccaaaaagca aatgtgcaat aagcaattta
    12901 gaaataagag gtaggcttgt ttaacgcaac aagctgtctg cctcatctac aatgctgcga
    12961 tgatatgata agcctgatga ttgcttctag acaaatcatc atcacttaat aacgctttat
    13021 attgtccatt gacaattgac tcatatacga aaggataaca aaatgtcaga tatttcatta
    13081 atttctgcaa tcttggtcgt tatcgttgcc ttctttgccg gtcttgaagg tatcttggac
    13141 caatttcaaa tgcaccaacc acttgttgcg tgtaccttaa tcggacttgt gactggtcac
    13201 cttgaagcag gtgttatgct tggtggtact cttcaaatgc ttgcacttgg ttgggcaaac
    13261 attggtgctg ctgtagctcc tgacgctgct cttgcatctg ttgcagcggc tattatcatg
    13321 gttaagggtg gcgactttac tcaaaaaggg attacctttg catactcaac agctattcct
    13381 cttgcggttg caggtctttt ccttactatg attgttcgta ccatttcaac tgtacttgtt
    13441 cacgctgggg acaaggctgc tttagagggt aacttctctg ctatcgagcg cttccacttt
    13501 gctgcacttc ttcttcaagg cttgcgtatt gctgtaccag ctgcacttct tgttgctgtg
    13561 ccaactgagg ccgttcaaag tgtcttgaag gctatgccag cttggttgaa tgaaggtatg
    13621 caaatcggtg gtgctatggt tgttgccgta ggttacgctc ttgttatcaa catgatggct
    13681 acacgtgagg tatggccatt cttcgcactt ggttttgccc ttgcagctgt gacccaatta
    13741 acacttatcg ctatgggtgt tatcggtgtg gctattgcct ttatctacct taacctttca
    13801 aaacaaggtg gtaacggtgg aggtcgagca ggctctgctg acccaatcgg cgatatccta
    13861 gaagactact agaaaggggt aagattaatg actgaacaaa ttaaattaac aaaagctgac
    13921 cgtaaacgtg tttggtggcg ttcacaattc cttcaagggt cttggaacta tgagcgtatg
    13981 caaaacatgg gttgggctta tgcacttatc ccagcactta aaaagcttta cacaactaaa
    14041 gaagatcgtg ctgctgcact tgagcgtcat atggaattct ttaacactca cccatatgtg
    14101 gctgctccta tcatcggggt aacgcttgcc cttgaagaag aacgtgccaa cggtactgct
    14161 attgacaacg ctgctatcca aggggttaag atcggtatga tgggacctct tgcaggtatc
    14221 ggtgatcctg tcttctggtt tacagtgcgt cctatccttg gtgctcttgg tgcttctctt
    14281 gcacaaactg gtaaccttgt cggtccactc cttttcttct ttggctggaa cattatccgt
    14341 atggccttct tgtggtacac tcaagaattt ggctacaagg ctggatctga aatcaccaaa
    14401 gacatgtcag gtggtatcct acaagacatc actaagggag cttctatcct tggtatgttt
    14461 atccttgctg tccttgtaca acgctgggta tctatcaact ttaccatcaa ccttccaggc
    14521 aagcagcttt ctgaaggtgc ctatgttgtc ttccctgagg gagccgttaa aggtgctgag
    14581 ctaaaaagta ttcttggaca agctatgggt ggcatgagcc ttgataaagt tcaatcacaa
    14641 acccttcaag ggcaattaga ctcattgatc ccaggacttg ctggattact acttaccttc
    14701 ctttgcatgt ggttattgaa gaaaaaagta tcaccaatcg caatcatcat tgccttgttt
    14761 gcatttggta tcatcgcaca ccttcttcac atcatgtaat aaaaattaag gaattggggg
    14821 cttcccagtt ccttaatttt tggctgtcta gagccttagc aaaggccagt attcagcctg
    14881 ctacaagcta tatttttatg ttataataga caaaaacact aaaggactta ttatggcaca
    14941 atctttaaat caaagggtga tccttcagac aacagccgtc tcctatcttg gaatcggagg
    15001 aaaggttggg aaaatcttac ttggagataa ggctttggaa ttttacaatg ataaaaacgt
    15061 tgaggacttc attcaaattc cctggacggc cattaaccaa atcggtgcca atgtttctgg
    15121 caaaaaggtc agtcgtcact ttgaaatctt taccgatcaa ggcaaatttc tctttgcttc
    15181 aaaggattca ggaaaaatct tgaaggttgc tagagaaaca attggcaatg acaaggtcat
    15241 caagctacca accttggtcc agaccataat agcaaagcta tttcatcatc aaaaaaagga
    15301 taagaaatct cattgatggg cctgccttaa ttcaatatta cggtcataga ccagcatgat
    15361 aatactctta gacatagcac catagcaata tgtctaagag tttttttcgt tgctaacaaa
    15421 aaagcttgaa aaacaagctt acagaatgta gacaaaccct atcagcgata gaaaaattga
    15481 aaatttagaa attgactatc atataatgaa aactctggaa aatgctgata ttacagtatt
    15541 tttcagaatt cttttgtttt tttgattaaa agaaaaagct tgaaaaacaa gcttaagtga
    15601 atcctttcta caatctaaat ctaaccttat tcctcatcaa tctgcaaagg ggattttctt
    15661 gtccacccat ttcaacaaat tttgaaagcc tagtttttta aaaagcatca gccttgcctg
    15721 ttcaaccaga aaggacaaaa aataaatcac aatgccgacg ccaaatatca gtagtgggta
    15781 taaaaggata ggagcattga caaagggctc tgcaaaatcg cgaataataa atttgaccag
    15841 caaggggtgt aagtgcacca gataaatacc tagagtcgtt ggagacacga tcacaataaa
    15901 gcgtagcagc agtgtttctg atgtcagctt cagcttagca aaaagaataa ataaggcaat
    15961 agctcccaag gtcaggctag gtgatacata ccagtaccaa atatttccca ccataaattt
    16021 catgatatag gtaactacca aagatcccat ataaaccgca ataagaagct tatgactaaa
    16081 cctacttagc tctatcctcc ttagataggc tccgataatg tagagaataa tcagccaagt
    16141 catttcaaag cccttgctta aggaaaattc atcgacctgc tggttcatca gagctgggat
    16201 caacgaaaaa atagcaaaaa ccagcagtac caatcggcct agctgcttat tggataaggt
    16261 attgaggcca ccattgatca taggcataaa aatcagtaac ccaaagtagg cggtgatata
    16321 ccaataattg ccactcacta tgggaaagag ggcctgacgc caattctcta agctaactgg
    16381 aaagccaaat agagcaaaca aaagggtcat cagaaagcta taaaagaaga cttgtaccca
    16441 aatattaacg attttggaat atttataggg cgacttaatg cccacatagc cactaatcaa
    16501 cgcatagcaa ttgaccgccc cataaacaag aacctgaatc atccaggtaa caataaaata
    16561 agaatctgcc tcaccttcga cagttgaccg caagccgccc tttcccaaaa catgtgtgat
    16621 cacaatcata aacatggaaa tgattcgcaa taaatctaaa ccgtaatggc ggttcttatc
    16681 taatgtcatt acatttttac gcataatatt agtttaccac aatttttaat atttaacgat
    16741 ttgattttgt ctgacaacga gattttttgt gcctctgacc taagctctac ttgtcatcag
    16801 ccttttgtat tactgacgct ccgtgacaga cacatgaaaa agttttagca agaaaagaaa
    16861 gctttctgta tttcaaggat atgtcttgtt ttttatagac tttactatag gaaaaacatt
    16921 gaaagtgtct actctaattc caaaataact agttcgcgcg tttgatgtag ctgacactca
    16981 tttgggagtt tactttttct ccttttttgt tataataggt ctagcggata agtagtctgg
    17041 ctctgtcttt cagagagtct gtggttgctg aaaacagata gaggagtcat acgaaattct
    17101 accgtctacc aattaaatat gaattaagtg cacagattgt gaagctggat ggaaccgcgc
    17161 ttaggcgctc cagtgtattc ataggctgtg cttttttatc tcgtcagaaa taaaaaagcg
    17221 atcagctagc tttgctcatg ctattttata actgactatc ttatcaccag ctcaaaggag
    17281 atttatttat gctagatctt aagcgtattc gtactgattt tgatactgtt gctgctaagc
    17341 tcaaaacacg tggtgtgtca gaagctatcc taacctctct aaaagcctta gatgaacagc
    17401 ggcgcaccct gcttgttcaa acagaagagc taaaagccca gcgtaatatc gcctctgctg
    17461 ctatcgctca agccaaacgc caaaaggaag acgccagcca acagattgct gacatgcagc
    17521 agctagctgc taacatcaag gcaattgatg ctaagctagc tgacattgac caagaaatta
    17581 ccggtatcat cactgttttg ccaaatactc cccatgattc agttcctatt ggagctgatg
    17641 aagaggacaa tgtagagatt catcgctggg gaaagccacg tcagtttgat tttgacatca
    17701 aggcgcattg ggatcttgga gaagccttag atatccttga ttgggagcgt ggcgcaaagg
    17761 ttaccggtgc tcgcttctta ttctataaaa atcttggtgc aaggctggag cgtgcccttt
    17821 ataacttcat gcttgatgag cacctaaaag agggctatca agaaatcatt cctccttata
    17881 tggttaatca tgactctatg tttggcactg gtcaatatcc aaaattcaag gaggatacct
    17941 ttgagctaga tgggacaaac tttgttctta tcccaactgc tgaagtccca ttaaccaatt
    18001 actatcgtgg tgacatcata gatggtaagg agctgccaat ctactttact gcaatgagcc
    18061 catcatttcg ctctgaggct ggctctgctg gccgcgacac tcgtggcttg attcgcttac
    18121 accaattcca taaggtcgaa atggttaagt ttgctaagcc cgaaacatct tatgaagagc
    18181 tggaaaaaat gaccgccaat gccgagcata ttctccaaaa gctaaagctc ccttatcgtg
    18241 tcttggctct ttgtactggg gatatgggct tttcggccgc taaaacctat gatttagagg
    18301 tttggatccc tgctcaaaac acctatcgcg aaatctcaag ctgctcaaat accgaagatt
    18361 tccaagcacg ccgcgcacaa attcgctacc gcgatgaggc agatggcaag gttaagctac
    18421 tgcacaccct aaatggctct gggcttgctg tcggacgtac cgtagctgct atcctagaaa
    18481 attaccaaaa tgaggacggc tcagtgacga ttccagaagt gcttcgtcct tatatgggtg
    18541 gactagaggt gatcaagcca cgttaaagcc aaagactggc cggataaggt gccaacaaga
    18601 cgattaatgg gctctatcat ttctgtagta gataaggaca cagtagaaat gatagggctt
    18661 ttttctatgt acaaaaaagg ctctttatca attgtagggg gacaaagagc cgattaatga
    18721 gattgatcct aacaataaag aagacctctg taactcctag ctaactgcta gccttacaga
    18781 ggtctttttt gatgtcctta atattttcta aagcgctggt agcgctgatc caataattcc
    18841 tctaagggct tggcctgtag ctgagtgatt tcgtcaatta agtgtgattt tatcatctca
    18901 acaatctcac tcgaaaaata accccgctcc ggaataaccc gatcaatgac gcccatttga
    18961 tacagctcag ctgcggtaat tttcatgagc tcagcagctt cagtagccct agagccatcc
    19021 ttccagagaa tagaggcaaa gccttctggg ctaagaacag cgtacatggt gttttccagc
    19081 atccaaacct gatcagcaac agctaaagct aaagcaccgc ctgagccgcc ttcgccaata
    19141 ataatagcaa tgataggaac cttgaggtca ctcatttcca tcaagtttct agcaatagct
    19201 tcaccttgac cgcgctcctc agcacctacg cccggataag ctcctgctgt attgataaag
    19261 gtaatcactg gacgaccaaa tttttcagcc tgcttcatta agcgtaaggc cttacgatag
    19321 ccctcagggt gcggctgccc aaaatttcta gccagattat cttgaagatt ttttcctttt
    19381 tgaataccaa tcactgtgac cggttgatca gccaaatagg caatcccacc aacaatagag
    19441 ccatcatcag caaactgacg atccccatgc aactccataa actcatcaaa aatcaggctg
    19501 gcataatcta gagctgtcat tcgaccctgg tcacgcgctt cctttaatat tcttgcgacg
    19561 tctgtcatga tacacctcca tgaaatgcca ccaaatgagc aatccgatca cgcaggtcag
    19621 tccgcttcac aatagcgtca acaaagccat gctcttttaa gaactctgcc ttttgaaaat
    19681 catctggtaa attttctcta actgtcgtct caatgacgcg tcgaccagca aaaccaacca
    19741 aggactgggg ctctgcaata atcatatcac cctccattgc aaagctcgct gtcacaccac
    19801 ctgtggtcgg atcagttagg atagtcaggt aaaaaagccc agcatttgaa tgtttcttta
    19861 tagctgcaga aaccttagcc atctgcatca gactcataat gccctcttgc atacgggctc
    19921 caccagacgc tgtaaaaata acaactggga gccgctcact aatagccagc tcaaataagc
    19981 gagtgatttt ctcaccaaca acggtcccca tgcttgccat gataaaatgc gaatccatga
    20041 tggctagagc aagcctttgt cccttgacca gagctgttcc agtcaggaca gcctcatgca
    20101 agccagtagc ctgcctggcc ttttgcagct tggcttggta gtctggaaat cttaatggat
    20161 ccttggtttc aatatctgta aacaattcct gaaaagagcc ttcatcaacg gttaaagtca
    20221 agcgctcctg agcagaaatc ctaaaattat aggagcaggt cggacaaatc tttgccggcc
    20281 ccagatcctt ttgataaatc atgtgcttac aggcaggaca cttggcaaat aattcgtctg
    20341 gcacctctgg aacattacga ctgacagagc ttttgagaga attattggga gtaatacgga
    20401 tatatttgtc ttttttacta aataaggcca tatctactcc taatctttat tgtagctggg
    20461 taaaaaggtt tccatcaaaa acgacgtatc gtaatcaccc gcaatcactt gcttgtctga
    20521 aatcaagtcc atctgaaaat caatattggt cataatacct tcaatctcta actcaaacag
    20581 agccctttgc atcttcatca aagcatcaaa tcggttatct ccatgaacga taatcttagc
    20641 aatcatacta tcataataag gcggtatcgt ataaccactg taaacagcag aatcaatcct
    20701 aagcccaaca cctccgcttg gtaggtaaag atctgtaatc ttaccagggc ttggtgcaaa
    20761 attaaagctt ggattttctg cgttaatacg acactcaata gcatggccag taatcacaat
    20821 atcctcttga cgaactgata aaggaagacc tgctgcgatc cgcaattgct ccttgacaat
    20881 gtcaacgcct gtaacaaact ctgttacggg gtgctctacc tgaacacgcg tattcatctc
    20941 cataaagtaa aaatcaccgc tggcttcatc taataagaac tcaattgtgc cagcattctc
    21001 ataggacacc gccttggcag cacgaacagc agcttcaccc atcctttgac gcagtgttgt
    21061 gccaatcgca atcgaagggc tttcctccag taccttttga ttgttacgct gtaaggagca
    21121 atctctctct ccaaggtgta tcacatgccc ctgtgaatca cctaaaattt gcacctcaat
    21181 atgccttgcc ggataaataa ccttctccaa atacatggca ccattaccaa aggctcctaa
    21241 agcttcttga ctagcagcgt taaaagcagc ctctaaatca gcctcggatt caacctttcg
    21301 gattcccttg ccgccaccgc ctgcagcagc ctttagcatt actggatagc caatctgcct
    21361 tgcaatctca agagcctctt gggcattgta aacctcgccg tctgagcctg gaataacagg
    21421 aacacctgcc ttaatcatct cagcgcgggc gttgattttg tcgcccattt tatccatgac
    21481 agctcctgag gggccaataa acttgatgtt catttcctcg cacatggtca caaattttga
    21541 attttcactt aaaaaaccaa accctgggtg gatagcctgc gcccctgtca ccacagctgc
    21601 tgataagaca gaattcatat tgagatagga ttcctttgat cttgacggtc caatacagat
    21661 ggcttggtct gccaagatcg tatgtaaagc ctctctatca gcctcagaat aaacagcaac
    21721 tgtggaaatg cctaattctc gtgctgcacg aataatccgc actgctattt caccacgatt
    21781 ggcaattaag attttgttaa acataggttc ttttttcctc cacagacgat tagtctttta
    21841 ctgcccaaaa gcaaaggtca aggtcccact agctgctaat ttgccatcaa cctctgcctt
    21901 ggcctcaaca actgctattg tcccacgacg cttaataaac ctagctgtca tgactagctg
    21961 gtctcccgga accacctgct ttttaaattt taccttgtcc ataccagcgt aaaaaacaag
    22021 cttgccttta ttttcctctt ttgatagctc caagacgcca gcagtttgtg ccaaggcctc
    22081 catgatcaaa acacctggca tgactggata ctgaggaaaa tgaccgttaa agaagggctc
    22141 attgatagtg acatttttga tggcaacaat ttcatcgtct gaagcctcta aaattctatc
    22201 aacaagcagc attgggtagc gatgtggcaa tgcctcttga atctgtttta tatccatcat
    22261 ttaatgcgta ccaatccttg tccaaactca accacgtcct cattggccac taaaatctct
    22321 gtcacgatac cgtcgcaagg agcaggaatc tcgttcatga ccttcatcgc ctcaacaatt
    22381 aacaatgtct gtcccttttt aacgctatca ccaacagtaa caaatggagg cttgtcagga
    22441 ccggcagcaa gataggccac accaacaaga ggactgtcaa ctacttctcc ttctggctct
    22501 tgcagacctg aagaagcagg gattgattcc tgtttagaga caatctcctg cgtcaggcta
    22561 ataggggcta cctcctggtg caaagtaaca ggctcaggag ctggagctgc catcggacgg
    22621 tgctcatttt tactaaataa cagctcccca tcacttgatt tgaatgaaaa ttcgcgtagg
    22681 cttgacgcat caaactgtgc catcaaatcc tttatctctt gaatattcat tttaatcctc
    22741 ccaacgctta aaggctaata cagcgttatg acctccaaag ccaaaggtat ttgacatggc
    22801 ataacgaata tcggcttctt ttccttggcc aaaaataaca tttgcttcaa tatcatctga
    22861 cagctccttt gtcccagctg tcattggaac ataattgtga cgtattgctt ctatggttgc
    22921 aatagcttcc acagcaccag ctgcccctag taggtggcct gtaaaggact tggttgatga
    22981 gacaggaacc tctttaccaa gcactgcaac aatagcctga ctttctcctt tttcattagc
    23041 aggagttgag gtgccatgag cattcacgta gtcaatagct gctgcatcaa taccggcctc
    23101 ctgcaatgct agattaatgg ccttacgagc accaagtcct tctgggtgtg gtgaggtcat
    23161 gtggtaagcg tcacaggtat tgccgtagcc aacaatctca gctaaaatag tcgcaccgcg
    23221 cttttgagca tgctctaagc tttccaaaac aagcatacct gatccttcac ccatgataaa
    23281 accgtttcga tccttatcaa atggaataga gctgcggctt gggtcctcag ttgttgacaa
    23341 ggcagtcaag ctctggaagc ccgcaatggc aaattttgta atggctgcct ctgatcctcc
    23401 aaccatcatc acgtcttgaa gaccaaactt aattgtacga aaggcatcgc caatagcatc
    23461 gtttgaagag gcacaggctg tattgattga cttacatacg ccttgggcat tcagcttcat
    23521 ggcaacatta ccagccgcca tatttggcaa ggcctttggt agagtcatcg gcttaacgcg
    23581 ctttggtcct ttttcatgta accgaatcac ctgctcttca atctcttgaa tgcctccaat
    23641 accagacgct acaataacac caaagcggtc agaatcaatc gcttcaatat ctaggccagc
    23701 atgttcaatc gcctctgtcg cagcatataa ggcatacaag gaatacatgt caaagcgatt
    23761 tagatccttt ttgacaaaat acttatcaaa tggaaaatcc tgaatctctg ctgcattctt
    23821 aacagcgaag tcactcgtat caaattttgt gataggctta ataccaatat gacctgcctt
    23881 taagcttgac caaaactcct ctggagtatg cccaattggg gaagtcacgc cataacctgt
    23941 tacaactact ctgtttaatg tcattttaat acctctattt tattgcattg tcatgccgcc
    24001 gtcaatggca agcacctgac cagtaatata atcctgacta gctaggaagc ttgctgcctg
    24061 agcaacctct tgccccttgc caatacgctt cattgggatt tgatttaaga tttgctcttg
    24121 catcttttca gaaaggacac ctgtcatatc agattcgatg aagcccggtg caatcgcatt
    24181 tacccgaatg ccacgcgccg caacctcacg agcaactgac ttggtaaagc caatcaagcc
    24241 tgccttggac gctgcataat ttgcttgacc gatatttcct gttaggccga caacactaga
    24301 cacattgatg atagcaccct gacgagcctt tgtcatcggc tttaagaccg attgtgtcat
    24361 gttaaatgct cctgtcagat tgattttgag aacacgctca aagtcctcct ctgacatctt
    24421 aagcattaat ttatcattag tgatgccagc attgttaatc aaaatgtcca cagagccaag
    24481 ctgctcaata gcctcatcaa ccattcgctt agcatcagcc ccctctgaaa catctcctga
    24541 gatcggcaca accttcacac cgtaatcctt aaaggtctcc accagctcat cagaaatcgc
    24601 tgagcgacca ttgagaacga tgttggcgcc tagtcctgca aattgatgag ccattgctag
    24661 tccaatgcct cttgttgacc ctgtgataaa aacgtttttt cctttaattt ccatagctta
    24721 gcattccctc ctattttccc aaatacaatt gtaggcttgg catatcttca acactgctgc
    24781 atagcagctt tttgtcgatt tttttaataa agcctgttaa aaccctgcca gggccaatct
    24841 caacaaactg ggtgataccg ttagccttca taacctcgat actatcataa aaacgaacag
    24901 gctccatgac ctgacgcgcc aataattctg caatccgatc cttttccatg accttagcct
    24961 ctgtatttcc aaccagtggc agatcaaagt cctgaaattg aatcttgctg agctcctctg
    25021 ccaacctttg actagcaggc gctaaaagtg ctgtatggaa aggtcctgag acattcagcg
    25081 gaattaaacg cttcactccc tttgctttta agatttcaag tgccgcattg acagcctcag
    25141 ctgtcccacc aataacaatc tgtcctggcg tattatagtt agcaggtgac acaacaccaa
    25201 ccgaagaagc ctcttgacaa gcctcctcaa taagcctagc ctctgtattc atcacagcta
    25261 ccatcttacc agagccagca ggcgctgcct cctccataaa gcgtcccctt tttgcaacta
    25321 gctctagggc agtctcaaaa ctcagaacac ctgccgcaac tagagcagaa tattctccaa
    25381 gagaaagccc cgccaccata tcaggatgaa ccccataaga ggttaagata cgataaatgg
    25441 agactgaagc ggttaagatt gctggctgcg tgtaggctgt ctggttcaac cgatcctggt
    25501 cggtatcaat gagcttgcgt aaatcatagc ctaaaagctg actagcctga tcaaaggtgt
    25561 cacgagcaat ggcatattgg tcatacaaat ctcttgtcat gcctagtgtc tgagcaccct
    25621 gaccagcaaa taaaaaggct gtttttgtca tacttctcct tatttatatc gtttcgtttt
    25681 tgtcatcagc tgcaagagct tgccagcgct tagcttcttg actaatcact gctgctgcac
    25741 catagtagat atcctttagg atggcttcac agctttcttc tgctctaatt aagcctgcaa
    25801 tctgccctgc catgacagag ccattgatca catcaccatc aatcacagcg ttgcgcagag
    25861 ctcctgctcc catttcttcg atgtcactag cagccttacg atctgctaaa aattcttttt
    25921 cagccttagc ataagctgat gttagcttat ttttgataga gcgtaccgga tgaccaacaa
    25981 cttgagctga aatgacagta tcaatgtcct tagccttcaa aattttatcc ttaaagcttt
    26041 ggtgagcatt agattccttt gccacaacaa atcgagttcc aacctgaaca gcctcagcac
    26101 ccagcataaa ggctgctgct gcacctcgac catctgcaat cccacctgct gcaataactg
    26161 gaatagaaac agcatctacc acctgcctaa ccaaggtcat cgttgtcaat ttaccgatat
    26221 ggccaccagc ctccattcct tcagcaataa cagcatcaac gcctaatttt tccatgcgct
    26281 tagccagggc aacgctagga acaactggaa tcacgataat acctgcctca tgaaggcgct
    26341 ccatgtattt ccctggattt ccagcgccag tggtcaccac cttgacacct tcttcgatca
    26401 ccaaatcgac aatgtcatct gcaaagggag atagcagcat gatattaacc ccaaagggct
    26461 tatctgtgat cgctttgaca cgatcaatat ttgccttgac cacctcttta ggagcgtttc
    26521 ctccaccaat gatcccaaga ccaccagcat tggagacagc acctgctaga tcaccatcag
    26581 ccacccaggc catacctccc tgaaaaatgg gataatcaat attaagtaat tctgtaatac
    26641 gtgttttcat aataaccttc tatgcaaaga aatcaggaga ataatttgat aatcaaacta
    26701 tcataataag aagaaagagc gagttagagc ctgaaagagg gtctaatctc accctgatgg
    26761 ttcgattatt acatatcaat tgaccaacta aagcagttca ttaatcagca ggctggttaa
    26821 tcagtattct cgcttgtttg agctttattt tgttttttct tcaacgtagg caacaaggtc
    26881 accaactgtg tttaagcctt cttctgtttc gatttgaatg tcaaaggcat cttcaatttc
    26941 tgagatcact tggaaaacat caagtgagtc agcatctaaa tcatcaaagg tagtttctaa
    27001 ggttacttcc tctgcgtcct tgccaagctc ctcaacgata atttcctgta ctttttcaaa
    27061 tactgccatt ttatgtctcc ttaatataaa tatttatttt ataaatgtgc taggcacatg
    27121 atataactag attttaacaa ttagactgcc ccatgtcaaa cctccaccga agcccgacag
    27181 taaaatatgc tggctgccgt ctaatttaag ctgtccattt tggactgatt cagatagcaa
    27241 aatcggtata ctagctgcac tggtattgcc atagtgcatc atattttcca gaaatttctc
    27301 tcttggcata ccaattttct tagccatctt atctaaaata cgccgattgg cctgatgtaa
    27361 aagcagatag tctaactcct ccttggccaa gcctgattgc tcaataattg ctgtaatgct
    27421 ccttgaaaca tctctaatcg caaagtcaaa gatagcacga ccatccatct gaagaaagga
    27481 gttgacctcc tgtccttgag aaaatggtga gcgcagactg ctctgacctg atgtcaggct
    27541 ttgaccttgc gcaccatcag tatgtaaggc ctcagctaga aaatgctgct gctcgctggc
    27601 ctctaataaa accccaccag caccatctcc aaataaaaca gctgtgcttc tatcctgcca
    27661 atcaataatc ttagacaggg tctctgctcc aataaccaag cctctttgat aagcccctga
    27721 tgcaatcaac ttatccgcca ttgctaaggc aaagacaaag ccactgcagg ccgctgtcat
    27781 atcaaaagca aatgcattag tagcaccgat agcagcctga acctttgctg ccgtcgatgg
    27841 catgctagca tctgggctaa tcgtagcaac gatgataaaa tcaagtgcag tcgcatcata
    27901 tcctgaccct gctaacaatt gctctgctac ccgaatggct aaatcactgg tcatctccac
    27961 agtggaaatg tgacgcttct caatcccagt ccgtgacgaa atccattcgt ggctggtgtc
    28021 catgatttgc gacagatcgt cattactaat aacctgctta ggcgtataat gagctacctg
    28081 actaattttt gaaaagacca ttaaaccaaa tcctccaaaa actgatgtaa gttccccaag
    28141 ccacgtaaca gggcttgcat ttcgtcctca ttcatatcag cgatcacatg accgaccata
    28201 tttttatgga atcttgcatg gagacgatcc agaagacgcc cctttttggt cagtgacagg
    28261 taaacaaccc gtctatccac gcttgatctt gttctttcaa tatagccctt tagctctagc
    28321 ttgtttaagc tagtggtaac cgttcctaag gtaaccatga gctctcttgc gatgtcactt
    28381 ggcgttacct gctgatattt tccaataatc tcaattgtgt gcatctcctt tagagaaaca
    28441 tcattaaatt gacttgtttt taagctcatt tcctcaataa ccaaaattct gttgaaaata
    28501 tcaactaaat attgattaat cttattatat tccaagtaaa cacctcccta gctgtaaaat
    28561 actttgacta tcaaagtata tcagacatca aagtattttg caagcacata agagctattt
    28621 cccccgaaaa tttggccgcc tcctatctcc ataagccctg acgccctctt taaagtcctc
    28681 cttaaaggcc aattcctctt gaatagcaag ctctttttgg gcataatcct cccaacctgc
    28741 aaaaaagctt tgccatacca aagatttcat gccggcgtag gaatttgaag agccacgcct
    28801 caaacgcttt aacagctgac tacaggtctt atcaagctta tctgactcag cagctcgata
    28861 gacaaatccg tactcaagcc ctttttctgc tgtgaccccc tcaccggtca tcaccagatg
    28921 agtcgctcta tttagaccaa cggcacgtgt taacaagaaa agaccaccag catctggcgc
    28981 taagccgaca ttaacaaagg cctgaataaa ttttgtctgg gtgctagcaa tacaaaaatc
    29041 caccgctaag gcaatattaa aggccgcacc agccaccgca ccatcagcac agaggataac
    29101 cggctttggc aattgcttga tagcaaagga aatatcctga accagctcag caatcctaac
    29161 tagagactga acatcatctc tttcaacagc attttgcatc tcaaccaagt caccaccgac
    29221 tgaaaagacc ttgccctttg ccttaatcac taaaaagcgc agagaggggt tatccttaac
    29281 caacctaata gcctccagaa tctcctgaca ggctggaatg ttaaagccat tagacacctc
    29341 tggacgattt aaggttaaaa tggccagatc ctcttcaagc tcaaaaatga tattttgaaa
    29401 cgtcatatca ctcctctttt ctgacagctt atttgattac caaataattt tatgaccaaa
    29461 taatttgaca atcaaattaa ttactagact atagtacact agaatcagtc gttatgcaag
    29521 aaaaagattg taaaaaatac attaaaattg actgcgcaat ttaaagcatg cagccctaaa
    29581 accaagctca gacctagcct ctatacctct aataaaagag cctaagacaa aagtgtccta
    29641 gactctgaaa ctttggcatg tgctatgctc aaccattcta tacaattgtg atcaatcgct
    29701 catagagtgt gtaaacaaga cccgcttaaa tatcctctag agcgtctttg accttgtcaa
    29761 agaaaccttt tttctttgga gcaatcggct tttcgccact agcctccgca aaagccttca
    29821 aggcctcctt ttgagcctca ttgagcttgg taggcgttac aatgtttaca gttacatgct
    29881 ggtctccttg gcctccgcct cgaagcttag gagccccctt gcccttcaag cgaaatacct
    29941 taccagtttg tgttccagcg ggaatagaca tggcaacatc accatggacc gttgggatat
    30001 ctactgtatc tcccaaagca gcctgaacaa atgaaatatt caagctgtag taaatagtag
    30061 agccattgcg ctcaaactgt ttacttggaa gcacgtttaa aataacgaac aaatcaccat
    30121 aaggtccacc attaaagcct gcttccccct gaccctgtag gcggatttgt tggccggttt
    30181 caacacctgc tgggattttt actgaaacct tatgaacctt cttttcatga ccagttccat
    30241 gacaggtatg gcaaggctct ttgatttctt gaccgctgcc atgacagaca tcacaggtca
    30301 cctgacgacg catcatgcca agtggggtct gcgtatcaac attgataacc cctgagccat
    30361 gacatttacg gcaggttgta ggacttgttc caggcttagc tcctgagcct gcacaggtgc
    30421 tacaggttga ttcacgatga tagctgacct ctttttcggt accaaaaaca gcttcctcaa
    30481 aagaaaggtt taccctatat tgaaggtcat cgccctgacg tggagcattg ggattacgca
    30541 taccaccacc gccaaaaaag cttgagaaaa tatcctcaaa gccgccaaag ccaccaccat
    30601 cgaagccgcc aaaaccgcct gcgccaccac caaagccacc gtttgctccg gctgccccgt
    30661 attgatcata ggctgcacgc ttttgtgaat cgcttagggt ttcataggct tcctgtacgt
    30721 ccttatattt ttgctcagct cccggctctt tattgatgtc tgggtggtat ttcttagaca
    30781 tcttacggta agctcgttta atatcatcgg ccgaagcgtc ctttgagacc ccaagacgat
    30841 catagtattc cgtattattc atttattctt tccttcattg acaaaaacag acggagcgag
    30901 gcgccccgcc tatttgattt ttatttattt agccttgcta tgctattttc tagcaattag
    30961 gggaggggac tatcgcctca gtttctagct ttactgagcg accttagctc ctcacagctt
    31021 atttttcagt gaactcacca tctacaacat catcgccact gtttgttgag cctgtatctg
    31081 ctgcaccttc tgcaccagcc tgggcttgtt gtgctgcggc tgcttgctcg tacattttaa
    31141 cagcaagggc ttgtgctttt tcattaagcg cttcaagctt agctttcata tcatcaaggt
    31201 cgcctgactc ttgagccttc ttaagctcat caagagctgt ttgagcagca tcacgctctg
    31261 tgtcaaagcc tttgccttca gtttctttaa tagtcttttc agttgcaaag atagcctggt
    31321 caacttcatt tttaaggtca acctcttcct tacgttttgc atcggcttca gcattggctt
    31381 cagcgtcttt catcatgcgt tcaatttctt cttcagaaag accatcgtta gatttgatga
    31441 caatatgttg ttctttttga gtacctaggt cttttgcctt aacagaaaca ataccgtttt
    31501 tgtcgatgtc aaaggttact tcgatttgtg ggataccacg aggggctgca ggaatgtctg
    31561 tcaattggaa gcgtccaagt gttttgttat ctgctgccat tgggcgttca ccctgaagca
    31621 cgtggatatc aacagctggc tggttgtctg ctgcagttga gaagacctgt gatttagagg
    31681 ttggaattgt tgtgttgcgg tcaataagct ttgtaaagac gccacccatt gtttcgatac
    31741 caagtgacaa tggtgtcacg tcaagaagaa caacgtcttt aacatcacca gtgatcacac
    31801 caccttggat agcagcaccc atcgctacaa cttcatcagg gttcactgat ttgtttggct
    31861 ctttgccagt ttcagcctta acagcttcaa ccacagctgg gatacgagtt gaaccaccaa
    31921 caaggataac ctcatcgatt tctgacaagc tcaagcctgc atcagacagc gcttggcgaa
    31981 caggaacctt cgtacgctct actaaatcac gagtcaggtc atcaaatttt gcacgagaca
    32041 ggctcatctc taagtgaagc ggaccagcag cgccagcagt gatgaatggc aatgaaattt
    32101 gagtttgagt gacacctgaa aggtcttttt tagctttttc agcagcgtcc ttcaagcgtt
    32161 gaagagccat tttatcttgt gataggtcaa taccgttttc tttcttgaat tctgctacta
    32221 agaaatcaat gattttttgg tcaaagtcgt caccaccgag cttgttgtca ccagcagttg
    32281 caagcacatc aaagacacca tcacccaatt caaggataga cacgtcaaag gtaccaccac
    32341 caaggtcaaa gactaagatc ttttcttctt tatctgtctt gtcaagaccg taagcaagag
    32401 ctgctgcagt tggttcgttg acgatacgtt ctacctcaag cccagcaatc ttacctgcgt
    32461 ccttagtagc ttgacgttgt gcatcgttga agtaggcagg aactgtgata acagcctttg
    32521 ttaccttttc accaaggtag tcctctgcat agcctttaag gtattgaaga atcattgctg
    32581 agatttcttg tggtgtgtat tctttaccat tagcagcaac cttttcagag gttcccatct
    32641 ttgatttgat tgagataaca gtgtcagggt ttgtcactgc ttgacgcttg gcagcgtcac
    32701 cgacaatgat ttcaccgttt ttaaatgaca ctactgaagg ggttgtgcgg ttgccttctg
    32761 ggttggcaat gattttgctt tctgttcctt caagaactgc tactgctgag tttgttgttc
    32821 ctaagtcaat accgataatt ttagacataa tattttttcc tcttttatat atttatgata
    32881 ctcctcttat gtggcacgga cgctagcagc ttcctatgga atctcatagc tgaaatttga
    32941 gcctaaagtc tcaaattttc cgagtcataa aacactagtg ttttatgact tttgccacgg
    33001 cgaagagtat cggtaatgct cacttcgttc gcttttgcta gcgcaaaaag cagcaatctt
    33061 atttcttatt ttcatagttt accgtcattt cggacatgat tcattttatt gattagctat
    33121 catcacggga taattgcgac gtgagatagc aaaatcgata ccattttgct atcgagctag
    33181 taaggagtct aggcaagccg ccacagcggt tgccgtctaa tgacgagcca tttcaatggc
    33241 catcattagt gactagttgt acacaaccac catcgctggt cttagtaagc gctcatgaag
    33301 cttatagcct ttttggaaaa cctgagcgat actatctgct gggtggtcat catctgctgg
    33361 tagggtttgg actgccatgt gcagattgtg gtcaaaggct tccacaggaa cctcttcaat
    33421 accttcttct ttaagggctt gaacaaggct ttcttgcacc atttctaggc cttttttgac
    33481 atcatctgtc agaccctcaa cagccaaagc acgctccaag ttatctaagc ttggaaggat
    33541 ttttttagct aaatcctgtg aacgatagcg ctgcaagctt tggcgttctt cattcgcacg
    33601 acgctgaata ttttgcattt ctgcgtgagc tctgaggtat ttattttcaa aatcttctgc
    33661 tcgctggaga gccaactcta gctcagatgg ttcctcggct gcttcatcag caataagctc
    33721 agctgattga tcagcttctt caactggctc tactgcttcc tcagcagcct catcaagaat
    33781 gtcctcttga tccttgagct cttcttttgg ttttttagac aaggtgtcta cccctttctt
    33841 acattttctt aaatcatatt aaggccttag tgaacctcat aatggttgct gtttaagtaa
    33901 cggtaataat ctcttagctt cacagccagt agctgaccaa tcacattaat caagctaaca
    33961 ctacgacgat aatccatatc aactggccca attaagctta agaggccaaa tcctctgtat
    34021 ggaattaaaa acttgtaggt cagcaaggtc acgtttgcta gggctggctc actgctgtca
    34081 gcaacctgaa ccgttgccat ctcttcctct gatagactct gtctgataga tagggctaag
    34141 cgctgctcct catcaagaaa ctgataggtc gcaagaccag catagtcaag ggcagcaacc
    34201 ttgccagaga caaaaatcgt ttctcgaaaa agcccgacaa agatataatc aaacaaatcc
    34261 aaaacattgt ctgtcaccgt aaaatacttc tgaacaatct gagggatttc ggttcgcagc
    34321 ttgtaatgaa cagtcataac atctttgcca agtaagcgat cagcaacaat gcccttaagc
    34381 accagcaaat cacgattcat aaaattctta ggaatggcaa actgtacggt caacggcttg
    34441 gactcatcta agctcaaaac tgccaaggca tcatgactag atagctgaac aatatcaaag
    34501 cctgtcagcc tttgccttgc aggctcaaca tctaaaatcg ccgccgtata gccggtcgta
    34561 tccgatagca tctggctggc tcttagcaaa acgtcctcca gcttaaaggc ctcaaaatca
    34621 aaggccttga ccagctgata aaggtcctgc tcatcaatgc tgccaagatt aagagaatgc
    34681 tctacaaaat atttaaagcc tgccgcactt ggcatgcgcc cacttgatgt gtgagccttc
    34741 tccagcaatc ctagtttttc aagctttgcc atgtcatttc taatagtggc actactagaa
    34801 gcaataagtg actgcaaagc cttagagcca actggttcat gggtctgtgt aaataaatct
    34861 acaataagat tcaaaatatt agattgtctc tctgtgatca caaaccaatc actccctttc
    34921 tgttagcact ctatacatcg gactgctaat ttataattct attatatcct tttaaactag
    34981 catgtcaaga aaaaaactca aaaaattagc actctttttt tagagtgcta atttttataa
    35041 aacattgaca gtgttgcctt tgacattatg cttgaaagaa gtaatagaga gccacttact
    35101 acctctcaga ctggtattgg cttctcccga ctcgctagct aaaaggagcg ctaagctgta
    35161 agggggatta gcttaactgc ctgaagcctt aaggcctaac aatcaagcct ttagtagagc
    35221 aggataaatc aggctgcgtg ctcacagctc ctactcttaa ggcttacacc ttcaagctga
    35281 tagaaagttg caatacctac taaagcaaat acctgagctt accggttgtt tcggtgtctt
    35341 tttcatctcc tcaatcatca tagcttgtca aacctcttgc ttcaatcagc tgcacaagcc
    35401 tttgggcata gcccttatca tcagaatagc gataggtctg cagactttta gcaggttttt
    35461 tatacccttt ttcggttgct aggctttggt aaagcttttt ctcctcgcct gtgccttgac
    35521 taagccatga taagtaagct ctgatagagt cctctctgtc ccgatagata gcataggctg
    35581 tcttgtgctt tgaggctgct tgcttcttga ggctaatgga agcctgccct ggagctggct
    35641 gcagtgaaaa aaggttgtgg tatttggccg ccaacagggt tctgccataa ttggtttcta
    35701 aaataatctg accaatcaaa atagaaggac gaatgccata gtttttggcc aatggcttga
    35761 cctccttagc aaccaactgg ataaattgcc tctctgtata gggaacagac atctcctgac
    35821 tggccgatgt gcctttggca ttgaacagca agggaccaat caaagccacc ataatgaaca
    35881 ctaaaaacac tagaaaatag gaaaatttaa gtcgttttct cattttttct ccttcaatcg
    35941 tgttaggtat tcttctaggc tgaggctatg agcggtaatg tatagggcag aggctttacc
    36001 aacatagcga taatgccagt cctcatactc aatccctgtg ctagtctgct tcccttttgg
    36061 atagcgcaaa ataaaaccaa attgtggagc tattttttga atctcctgtg ccaccttagg
    36121 atcactagcg tttaagttat ctactgtgct catatcaatg gctagaccag tctgatgttc
    36181 actagtgcct gctggctggg catatttccg aaccaaggct tcagctgcct cttgggtcag
    36241 gctaggatca tttgccagct cttgggcaat ataagactga taaagctctt cttgctggac
    36301 aaccgaacga taaccagcaa tcaagtgctc ctgaggttca atcgtctgcg ccgctgctag
    36361 aaaatcagcc gtctcctgct caatgcgctt atcaatagga atcccattaa tctcaaccaa
    36421 ctcaggactc atttcctctt gagggtgatc gcgattgaca aggaccagct gccagtccgt
    36481 agttgatacc tttggcagat cagtagtctt tttagcctgc ttagctgcct ttggggcagg
    36541 tactgtttga ttagccttgg ggcctacagc ctgtttttca ggcttgataa agaggtaaac
    36601 ccctgataaa aacaacagga cgaccaaggc ctgtaaaagg actcttatag tgttattctt
    36661 catctcttat tgactcaatt atctcacgac cacgatagcg gtagctcata tctccaatcg
    36721 ttttgatggt aaactgccca ttctcatatt ccacaacagt gacgcttcca ttgtcaatgt
    36781 attgcttttc cctatctggg tcaattagcc acataaaggt tccaatggtc atgccatgac
    36841 taaccacgat agcattgcca cctcctgcat tttcaacagc aagcgcgata gcctcaaagc
    36901 cctcatagat acgcttgctc aatacctccc agggctctgc ccagttagca gtatcaacct
    36961 cgacaatact ctctgctaat tctgaataag gcacatcacg cagattgtca cgattttcaa
    37021 aggcctttgt tctaggtaaa acacctaaaa acagctcgga atcataagcc ccatctagac
    37081 taccaaagca ccactcacga atccgcttat ctctagtgta gggtaaaaac tcattttcag
    37141 actttcgtag aataatctcc attgtctgca tggtacgacc tgaatcactc gaaaaagcag
    37201 ccttgaatgg aataccagca gccttcaaac caagtcccaa ttcacgaatc ccttcttctc
    37261 ctgcctttgt caagggggta tcactccaac cctgtgcacg accaatggtg ttgaacatcg
    37321 tcttgccatg tctgacaatg tataatcttg tttttgtcat aatgaacctc caaagtctct
    37381 ctgctattat agcattaaaa gaaaacactt gcaaaaccat gcaagtgcta gccgttaatt
    37441 cttaaagcta tggataggag ctggtatctg cccaccacga gcaataaagt cagccgatga
    37501 atgcggatta acagccataa ccggagctgt ccctaaaaga ccaccaaaag caatcatatc
    37561 accctcctta ccctttggaa taatacgaac agctgttgtc ttttgattaa tcaccccgat
    37621 agctgcctca tcagcaatca tggctgcaat ggtttcagac ggtgtctcct ctgggatcgc
    37681 aatcatatcc aaaccaaccg agcaaatggc agtcatggct tctagctttt caagattaag
    37741 cgagcctccc tgcactgctg caatcatgcc ctcgtcctct gatacaggga taaaggcacc
    37801 tgacaaccca cccactcggt tgcaagccat gacaccaccc tttttgactg cgtcattaag
    37861 taaagctagg gcagctgtcg tgccatgtgt gccaactatt tcaagtccca tctcctctaa
    37921 gacacgtgcc acagagtcac caactgctgg agtgggagct agcgacagat ccacaacacc
    37981 aaagcccaca cctagccgct cacttgccat ctgtcccact agctgaccga tacgcgtgat
    38041 tttaaaggcc gtttttttga cggtctcggc tagaacgtca aagctttcac cacgaacctt
    38101 ttccaaggct cttttgacca caccaggtcc tgaaacacca acgttaatca ccgtatccgc
    38161 ctcaccgaca ccatgaaagg ctcctgccat aaaaggattg tcctcaacag cattagcaaa
    38221 gactactagc tttgctgccc ctatctcaga ggctttggcg gtttccttga tgatacgccc
    38281 catgtctgca actgctgtca tattaatacc agaccttgtt gatccaacat tgaccgaagc
    38341 gcagaccttc tgtgtttgag ccaaagcctg aggaatagac tcaatcaaaa tcttatcacc
    38401 cttttgatag cctttttgca caagagctga aaagccaccg ataaagtcaa ctccgatatc
    38461 acaggcagcc tgatccagag cttttgcaag cgacaggtag tcttctgcgt ctgttgccgc
    38521 cccaataagg gctatcggag ttacagagac gcgcttatta acaatgggaa tacctagttc
    38581 tgctgcaatg tcatcaccaa ccgccacaag attagctgcc tttgtcgtaa tcttttggta
    38641 aatcttagcg gcagctctat caatatccga atcaatacaa tccagcaagg aaattcccat
    38701 cgtaatggta cgaatatcaa aatgctgctc ctcaatcatc tcaactgttt cacgaacctg
    38761 tctaatatcc atagtcatca agctccttat atgttatgca tagcatcaaa aatcgctgcg
    38821 ctttgaatat taatcgtcac ctgcaattgc tttccataag cctgaagcac ctcacgcaga
    38881 tgagcaaaat cctgcttttc actgcttgag acaatggcca tcatggtaaa ataatcatct
    38941 aaaacggtct gtgaaatgtc atcaatattt aaccctaatg cagcaatttg tcctgaaaca
    39001 cctgcgacaa tcccttgatt gtccttacca acaactgtaa tgatagcttt catggcacac
    39061 ctcctcaata tgtgttatat tttatcacaa acaaaaagag aaagctatca gagacaagag
    39121 gtctggtagc cccttgcaaa aatagaacaa tgggtaccag aaaaaagagt ttgttatcca
    39181 attgataccg tttattaata tttagacttt ataatataat agcagctaat aaaagataag
    39241 acgtttgaag ctgccaaaaa agctgggtct aaggaagccc agcttttttg taggttaatt
    39301 aagggatagc agaagattag tcgggattgt aagaatagcc gtatcctctc ttaccacctc
    39361 tatcagctag accatctaaa tagccatttc cataattatc attataccct tgactatagt
    39421 cattatattc ctttggacta gactcatcaa accgcttagg ataatctcct ttgtgctttt
    39481 tgccaccata tccatcctca tagccaactc ggtaaccatc acgacgacca tgattgtagg
    39541 ggtgttcgtc tttaagtttt ggtgattcat cattttctcc gcttaagcct ttaccgtcta
    39601 aatcttcctt tggcttattc tctccatcta atccttttaa aggattttta cgattatttc
    39661 cttctaaatt cggagttgat gggggaccgg cttcacctcg ttcaccttgc tctggttcct
    39721 tctgattctc accattcaag cctggaagcg aaggacggcc ttgattatta ccactcaacc
    39781 ctgaaagtgg gggaccagcc tcacctcgtt caccttgctc cggttccttc tgattttcac
    39841 cattcaagcc tttttctggc agcttgggac tattgccctg aggctttggt tgaggctgcg
    39901 ggctagaatt atccttacct agatctaagt gctgtggctt tccttgtggc tgatggtgat
    39961 gacctgaacc agagctgtta cctcctctca gccccagtgg ctgggaaggc ccttgattag
    40021 gaatagcctg aggctctgag gcctgtccac tactatttcc ttggctgttc acactgagag
    40081 actgaggttg attcccatga tgacctgagc tctttgctgt cggctgggac gggctagtag
    40141 cctgatgctg atgattagta ggctgatctg aaggcttagg ctgcaagtta tcctttttcg
    40201 gtggccgact gaccattgaa tctgatgagc tcttgtgcga cttatcgtca tctccaatcg
    40261 agctgactgg ctgctccttt ggcctcgctt gatgggatga gccaccaaga cttcctaata
    40321 aacctccaaa gacaagtgca gctcccagca gcaagctggt caccactgca ccggcaaata
    40381 gccattgttt tttggacttc catgtgcgaa aacgtccttc tgtttttctc atactttttt
    40441 aactctctcc atattttttg gtaaaaatac caagaaatag tatatatagt caagacttta
    40501 tcatatttct tttaaatttt tatcatctga tatattcgat tgtttttaca aatctgataa
    40561 ccaaaaaatc ctcgtatcat actgatacaa ggatttttat atatttgaac gtcacaagta
    40621 ctcctggctt attgtttttt gccaaagagc gctgaagcaa caattatcac aatagctgct
    40681 cctagaattg aagggaaaac agccatgcct gccagctgaa taccccagtc gccaaacagc
    40741 ttttgaccaa ctgcagagcc tatcaaacca gcagcagtca ttgtgaaaca gcccatcgaa
    40801 tggctttttt ctgttatcct acctgcaacc atgccgataa tagctccaac aattaatgac
    40861 caaaccatcg caaatctcct ttatgttttg tcttattata ccataccctt gccttatatc
    40921 agtcagatga tggtggtcgc ttgatattaa gagcaagctg cttttttctc ttagtaagca
    40981 ataagtctct cagcgatatc acaagcactg ctattaaaat caaggccatt cctaacagat
    41041 caatagggtg aaaaatctct ttcatcagga taatcgcaaa gcagacagag gcaaccggct
    41101 caattgaagc cagcaaggta gccttgatcg gtccaatgat tgaagccccc tttagaaaaa
    41161 aggtgtaggc aaaaattgtc ccaataccga taatgccaaa cagggcccgt agattcccat
    41221 aagtcattgc caatgggtac tgccatgctc ttgtcaggat cggaaaaatc actcctccca
    41281 tcagcatggc aagaccaaca atcagcaagc tcccccagtc ggcaatcagc ttagcaggct
    41341 tgatgacaca gtaagcatag gtcaccgctg caaaaagccc ccagaaaagt ccaataggat
    41401 tgattgccag atgggaaaga tcaccatgac aggccatgat aaccgttcct aggatcgcta
    41461 ggcaaatagc acagctctct cccacagccg gcaggcgtct tgatttgaac gataggtaga
    41521 ccagcaccaa aatgggggaa aggtattgca ggactgtggc tgtaccagca ttagagtaac
    41581 gaatagcaag cagataggca tattgattaa gtgtgagacc aaatagactg taaatcaaca
    41641 gctctcttaa aagccttttg tccttgagta agctgatgac agcctctctt tgccgcacat
    41701 aagccatagc tgacagcaca agccctgaaa taatgagcct tagtgaggtc aaggcattga
    41761 tgccgacccc atgagcaatt aaatattgcc ctgacacccc tgagagaccc caggcgattc
    41821 cggctagtaa aatcatggta ctgccttttc catttcttga catattatct tcctcttttt
    41881 aatccatgcc atgataaggc cactcataat accttgatag ctctagccta gacttcacca
    41941 agcctgctta acagtcatta acaacagacc gataagctac ctcttacagc ttcggatagc
    42001 gaggtattat cacagaattg tcctaaagag cctaccatca taaagagcct gaaaactctg
    42061 tttcagactc aatgccagtc ataacgactc cttaatccag caatttttgc aattcttggg
    42121 ctaacaattg ctgagctatc tgtgggttgg cttgcccctt tgtggccttc atcagaaaac
    42181 cagtaaaggc cttgtcagca ttgcgcttgc ctgatttgaa atctgccaca gcagcctcat
    42241 tgtcagcaaa cacctgatga atgattggaa tcaagacagc tgggtctgaa atttgaacca
    42301 agccggcctt ttccacataa gcacgcgctg agccgccatg ctttgccaaa tgaacaaaaa
    42361 ccttcttggc gatttttgat gaaatcgtgc catcagtgat gatcgcaatc atttccacga
    42421 gattttctgg ggtcaaggca atctgatcaa tcgtcttgcc ctcagcattt aagaattgag
    42481 ccatctcacc ctgaagccaa ttagacacct gcttaggatc accaccaagt gccacagcct
    42541 gctcaaagaa atcagacaaa gcctttgttg ctgtcagctg acctgcatca taggctgaca
    42601 agccaagagc attaatgtag ctagctcgcc tgtctgccgg aaatcttgga agctctgcac
    42661 gcatatcctc aatccatgcg tcatcaatct caaacaatgg caaatctggc tctgggaaat
    42721 agcggtagtc tgctgctccc tccttgacac gcatgagaat cgttccctta cttgcctcgt
    42781 cataacgacg tgtctcctga cgaataacac cgccagagcg taggattttg gcttgacgct
    42841 ccacctcaaa ctcaagcccc ttacgcacat tgctaaatga gttcaggttt ttcaattctg
    42901 tttttgtacc aaaggcctct tgtccgtatg gtcgcaagga gatattggcg tccacacgca
    42961 tggacccctc ttccatcttg acatcagaaa taccagtata ctgaatgatt tcctttaggg
    43021 cagtcaggta agcataggcc tcctctggag agcgcatgtc agcctctgag acgatctcaa
    43081 tcaagggcac tccctgacga ttgaggtcaa cataggaata accatctgta ccatgcgtat
    43141 ttttgccggc atcctcttct aggtgagcac gctcaatacg gattttcttg gttgagccgt
    43201 cctcaagagt aatatcaatc cagccattgt agccaatcgg ctcatcaaac tgtgaaatct
    43261 gataggcctt gggattgtct gggtagaaat aattcttacg gtcaaagtgc atgtgctgat
    43321 gaatagacat gttaagagca agtgctgctt tgattcccgc atcaatgact cccttgttca
    43381 tcactggaag gacacctggg aaagaccagt caatcacatt agtgctggca tttggatcct
    43441 ctccaaaatg agctgatgaa ggtgagaaaa tcttagaatt ggtattcaac tccacatgga
    43501 cctcaagtcc aataatggtt tcaaaattca ttacctgtca cctccaaaaa tcataggctg
    43561 ctgcttgtgg tagtcagtag tcgcttcaaa ggctaccgct acctgataga tgacctcttc
    43621 gctatatttt ggaccgatca attgaagccc aacaggcaag ccatctgcaa agcctgctgg
    43681 aatagagatt gcaggcaagc ccgctagatt caccggaatg gtcaaaagat cagccaaata
    43741 catggcaaca ggatcatgat tcaacgtatc aagctcaaag gctgctgttg gtgctgttgg
    43801 tcctaaaatc aagtcataat cagcaaaaac cttctcaaag tcttgaatga tcagcgtccg
    43861 aacctgacct gcctttttga aataagcatc gtaatagcct gatgataagc taaaggtacc
    43921 aagcatgata cgacgcttaa cctcatcacc aaagccctga ctacgcgtct tgacatagat
    43981 gtcctcaagg ctcttggcat cagcagcacg aaagccatag cgaataccat caaagcgctg
    44041 taggtttgat gaggcctcag atgaagcgat gatataatag acagccaccc catacttgct
    44101 atgtggcaga ctgacctcct caatgatagc tcctagcttc tcaaaatgct tagcagcagc
    44161 caaaaccgtc tccttaatct taggatcaat gccttcgcca aggtattcct taggtagtgc
    44221 aatcttcatg cccttgatgt cttgaccgat cttaattgtg tagtcagcga tctgtacagg
    44281 tgctgaggtt gagtccttgc ggtcactccc tgcaatgacc gatagcagct gggcattttc
    44341 tcttaccgtt ggcgcaaaag gccctatctg atctagcgag ctgccaaagg caatcaagcc
    44401 atagcgagaa acagccccat aggtcggctt aagcccaaca acaccattaa aggctgctgg
    44461 ctgacgaata gagccgccag tgtctgagcc aagagataag cgaacctgac ctgaagctac
    44521 tgctgttgca gagccacctg atgaaccacc aggaaccctg ctatgatccc aagcgttttt
    44581 ggttttcttg aaataagacg tttctgttga gccacccata gcaaactcgt ccatattggt
    44641 cttaccaata acaatcatat ccttgtcgta ggcattagct accgctgtcg catcaaaaat
    44701 cggctcataa ttataaagca tcttagaagc agcagttgtc agaatcccct tggttgagat
    44761 attgtccttg acagctagtg gtattcctga catcacattg tcaggatcaa tccccttagc
    44821 atcaagtgca gcagcctgct ttaaagcagc ctcgcaagca atggtaatga aagaacccac
    44881 agcctcctca cgcgccttga tatcctcaag ggttgccttt gttagctcaa ctgcagaaat
    44941 gtcctttgca acaagaagct catgtaattc ttctatagta tgatgattaa aagacattag
    45001 gcatctcctc cgtcatcaag aatagctggt accttgatga aatgattttc tttttcagga
    45061 acattttgaa acaggagctt gcgatccact ccagcctcag cgatatcagc tcgcatgata
    45121 tttttcttgt ctgccattgt ggtggtaatg gcaacacctg tcgtatccac ttcatttagc
    45181 aattcaacca tgtcaacgat ttttgataat gttgtcgcaa actcagttgt ttcactttct
    45241 gaaaaggata gctttgatag ggccgcaacg tggcgaacct cttcttcaga aattttcatg
    45301 aattctccta tccaaggtaa agcagaccat catcagccac aaggccttgc tgtttcaaac
    45361 gcttgataat agcctgaata acccaatttt acatagtctt aaccattata tcataattag
    45421 ctttatttac catagcggac tgctgggatt tcacgtcaaa tgcatgtggc aactgacgtt
    45481 ttctgataac gtttttcata agctcaacct gcttttttca agaacagcca ggctataact
    45541 aaactgcatt tgagcaattg atgaggttaa aagggcaatg tggctagagc atagctacct
    45601 gcattttatt cacgtgtatg cgtagctggg attagcgaaa aacttaataa caaaaagcct
    45661 cctagccaag accaaaagat ctcactaaga agcccttaag atcagcgctg agccaagcag
    45721 cagctaatac tgccttactt gattagccta tcccagctga tcgaacgatc gcctaagaaa
    45781 gccgatcaag aagctttgct cctaggacag tcctacagtg gttcagcgcc cactggtgat
    45841 tttctgttga attgctcgcc actgctgatg tgataatctc aagcttgtag cccaatttat
    45901 aggcatcaat cgctgtatga aggacacaaa tatccgtcag cacacctgtc aagaccagcg
    45961 tcgtgacgcc acgctcacga agacgaatat ccaaatcagt ccccgaaaag gcagaataat
    46021 gccgcttatc cagccaaaag acccgctgat cttgctggta tctggtatat acggtcatca
    46081 aaggaccata caggtcccga ccccttgtcc cgataatatt atgcggcgga aacaaggctg
    46141 cctccggatg aaagctatct ccctcctcgt gggcatcaat cgcaaaaaag atatagtagc
    46201 cggcctcaaa ggcagcctca acaacgctag ccatcgcctc tgaaatcacc tgagcaggtg
    46261 ctcctgccgt caggctacca tcatcagcta caaagtcatt cgtgtaatca atagaaatca
    46321 aggccttcac agcttatccc tccccaaaaa gcttatgctc tcttagctgc atgacagcaa
    46381 gccataagaa ctaagcctgc ttttaatatt cagtatgatt agacacttat agtttaccac
    46441 taaacacgac agctgtcaag acagcggatt gatttataca cgataaaggc gaaaaacagt
    46501 tatttctgaa ctatagtata gatttaagta gacactttca acgtttttct atatgaaaat
    46561 aagatatatt cctgaaatag ctgaacattg aaatacagaa agccttattt tcttgctaaa
    46621 aatctttcat gcatctgtca tgttcatctc atgctgaatc acagcgaaaa tacaaaaaat
    46681 acccctcaaa agccagccaa tgctagaacc tttgagggga cgctataata atgtgtgaag
    46741 tcctccacag ctgctaagaa actccgataa gccgtcataa agaccaagtc tagcccttac
    46801 caagcagggc tctggctaat gaatggctgc tctataagca gcaagacttt gatcatagct
    46861 aacactttca ctacctgctc tgactaatca cagctagcaa agctaaaggc aagccttggg
    46921 cttagcagac gatcgcatct gagctattaa aattccttta gcttgtcaaa gatgccttcg
    46981 ttaatcacct tgagataagt gcctttcatt cctagagagc gactctcaat gatacctgca
    47041 ctctctagct ttctaagggc attcacgatg acagatcgtg tgattccaat acgatctgca
    47101 atcactgaag cggtcaggcg tccttcattg ccatctagct cactaaggat agctgcaaca
    47161 gccttcattt cagagtaaga tagagtgttg attgccatat taacaactgt ctgcttacga
    47221 atggtttctt ctaggttttc tgtttgaaga tttaacagct gaataccgac cacagtgctt
    47281 gagatttcaa ctaaaacaag gtcatcatca ctgaattcat tgtcgttacg ccagatgatc
    47341 aaggtaccta agcgcatgcc gccaccatag ataggggcaa tcgtggttaa accatcagga
    47401 tagatatcct ttgactcaat aggaaaaatc gttagttcat tttccacaga aaggtttgct
    47461 tcagtgtcat aaacacgact agctgccttg acataagcat ctgggaactg tcttgtttca
    47521 aaaaattcct cgacgcggtc tgtgttggtc ttgtacttca tcgcatagcc aagtaagctg
    47581 ccgccaccat tgatgataca agcattacaa tcaataatat ctgctaagcg tgaagccata
    47641 gtgttatagg ggagttctgt ttccaagctg tctacagaac gttgcaaaat agaagtaatc
    47701 ttacgggttt tttctaataa atttggcatt ttttcttttc cttttaatta tttgcgttac
    47761 aattatatca aaggacccta gcttttgcaa ggaattatca gaaaattggc tattatacct
    47821 acaattcgga tgaggccaga gccttatttt gctgaaaaac aaaaaggatc tcgcgatcca
    47881 atttttgtat gagaatcata ttagcgcttg tattgcttga gaacatgcgt gatcttttct
    47941 tgcacgtcag ctagctcttc tactgttggc agatagacca cgcgaaaatg atcaggctcc
    48001 ttccagttga agccacgccc atgtaccagc atgacctttt cttgcttcaa aagctgtagg
    48061 acaaattcct cgtcgtcatc aatgcggtac atatttcgat caattttcgg aaacaaatag
    48121 aggcctgcct taggctttac agctgatagg cctggaatgg cattaatggc ctggtaaatg
    48181 aagttacgtt gctcaaagat gcgaccaccc ggaagcaaga gctcatcaac agactgacgt
    48241 cctcctaagg aggtctgcac cacctgctgc gctaagacat tggagcacaa gcgcatgttt
    48301 gccagcatgt tcaagccttc aatgtaacct ctgacatgtc ttttagggcc tgacaagacc
    48361 atccagccca ctcgaaagcc ggcaatacgg tgtgattttg acagcccatt cattgacacg
    48421 caaaaaacat caggtgcaag gctggcaatt gcgatatgct ccccaccgtc catgaccaaa
    48481 cgatcataaa tctcatctgc aaaaatgata agctgatgct ctctggcaat tgcaacaatc
    48541 tcctctaaga cctctcgagg gtagagagca cctgttgggt tattgggatt gataatgacg
    48601 atagcttttg tgcgctcagt gatcttggct tttatgtcag caatatcagg ataccattca
    48661 gcctcttcat cacacaggta atgcaccgca tgcccaccac ctaggctgac acaggctgtc
    48721 caaaggggat agtcaggcat tggcaccagc acctcatcac cattatcgag caaggcttga
    48781 agagacatcg aaatcagctc tgagacacca tttcccaaat aaatatcatc aatgtcaaca
    48841 tcaggaaagc cctttagctg acaatattgc atgatggcct tacgagctga aaaaatcccc
    48901 ttgctatcag aatagccctc gctggagcga gcattgagaa tcaaatcacg aataacctca
    48961 tctggagcct caaagccaaa ggctgctggg ttacctgtat ttaatcgaag gatcttttca
    49021 ccattagcta tcatacgatt agcctcgtcc aggactggac ctcgaatatc gtaggctacg
    49081 tgttctaatt ttgatgattt ttcaattatt ttcatagtct cattacctcg taacccatat
    49141 tataaaccaa aacaattaaa atagaaagca cttttctatg agcttaaaga atgccaaaag
    49201 ctcaaccaaa gctctaagca agctaagcag cagctattaa taaggctatc taagctagct
    49261 tctagctcaa ggtatcctca cctcagggaa tagctgggct atttggtgaa caatagctca
    49321 gaaaatcatt aaaacgtttt caatttctcc tcaaaaaagg tataatagct atagagataa
    49381 agttcaaagg aggataaacc gatgtcacaa acatatgaac gtatcatggt cgctattgat
    49441 ggctctcatg gctccgaatt agcctttcac aagggggtta atgtcgcttt gcgtaatggt
    49501 gctgccttga ttttgaccca tgttgttgat acacgtgcgc tgcaaagcgt tgcaaccttt
    49561 gatagctaca tttatgacaa gttggagcag gaagctaaag aggtcttggg ggattttgaa
    49621 aaacaagcac gcgaggcagg gctgactgag gtcaagcagg tgattgaatt tggcaatccc
    49681 aaaacgctat tagcgcacga tatccctgac aaagaagagg ttgatttgat tatggttggg
    49741 gcaactgggc ttaacacctt tgagcggttg ctgattggat catcatctga atatatcctt
    49801 cgtcatgcca aggttgacct attagtggtt cgagagcatg acaaaaccct gtagcaagac
    49861 gaattctctc agctgtcaga agcatttgca gcctaagtga agtaaccata cctagccctt
    49921 agcctcagct cacaaggcta ctaaaggact actgctctca tatactaatt accactagct
    49981 agacttaagg gcccttttat tgagggtgtc tagtctacat caaaaagcac cctgagctaa
    50041 taagtgaagt gaccccaagt gttaggccaa atgcttaaca gctaggagat caactcacag
    50101 ctcaaggtgc tttttaatgc ctctaaaata aagacagcct tatttttcca agcgctgcaa
    50161 tgatttttga agctgcttgt ccaactcttt tttgatggct gactctggtg catagcgctc
    50221 ctgccagtca tctggctttt gaattttatg cgttatggga tcaaaatgcg ctttcccatc
    50281 agggaaaatt ttccccatat tggcttcatg gacggtctca aaaatgggct gagggtccac
    50341 tcccatcaat acaaatgagc cataggtaaa ataaagcaga tctgtcaaag catcaacctg
    50401 cccaaccagg ggtgactctg ggtgctcctt ggcctgcacc ttcttagctg ccttatcaag
    50461 ggcagcatgg aggtctatca aagcctgaga aaagcgatgc ttatcccctt gactggctgc
    50521 ataaagaaat tccacaagtt cctctacctt aaaatctgct cgatagccag cctcctttaa
    50581 ggaatagcct cttggtgttt caatcgtgtc tccgtccatc aggcggtgga aatccttgac
    50641 cttgttgaaa ttatcatcgc gacttttaaa gcttttttcc acatcaaaat gaatcaagcc
    50701 ataatgcgcc agcgccttag agataccatc attgttattt gaagctgttg taaagtgagc
    50761 accgctttta accactgcct cagcatttcc catcgcaaca ccaacaccaa cgcctgagag
    50821 catttctaag tcattatcag agtcgccaaa ggccatgacc tctgagagct caaagccaaa
    50881 catctcgccc aagcgttcaa tgcccttgat tttagactgc ccgctagaaa tcaaatctaa
    50941 ggaataaggg ctgcttctgg ttaccttgat atgcgggaat ctttccttga ttttttgggt
    51001 gtcatcaaca gaagcaacca agacaatctg ataaatcggc tctctcataa tggtaacaag
    51061 attgctgaag ctttgcggct taaagcgtct gatgaggttt ttaaagctgc cctcaaccgt
    51121 cttgaccaga ctccttggca caatactgct aaccatctga ccaaatggac tggttcccat
    51181 atcaatgatc cgagacccag caagacctga agctgttcct aaggagatct cgcgcttttt
    51241 atcgctagca tagcgaatga ttttataaat ggttgacttt ggcagctggt tctgatacaa
    51301 gaccttgtct cgtgtcaaaa tgtattgacc attgtaggtc actgcaaaat ccaagccaaa
    51361 attttctaaa aagggctgca caaaagcagg tccacgacca gttgccagcc caaccataat
    51421 accttgtttt tttaattgct gaatagccct ttgcgtcgtt ttttgaacat tttttcgatc
    51481 attaagcagg gttccatcaa tgtcgaaaaa gactgctttt attgtcaaat ccttctgttc
    51541 tctcttctat ttgtgataaa ataaattata tcataaattg aaagaagtat gagtatcaaa
    51601 tgaaggaaat cctcgtctta cataccggcg gcaccatttc aatgcaggct gatgaagcag
    51661 gcaaggtgag cccaaatcaa aacaatccaa tgaatcaggt tggccttagc ctggagcata
    51721 tccacctaac tgttgtggat tttttaaatc tgccaagccc gcacatcacc cctcaccaca
    51781 tgctcaagat gtatcattac attcaacaaa gggctagtca gtttgatgca gtggtcatca
    51841 cacatggtac agatacctta gaagagactg cttattttct agacacaatg gtgctgcctg
    51901 tagagttgcc tattgttatc acaggtgcta tgcgctcggc caacgagatt ggaagcgatg
    51961 gtatctataa ctacctaaca gcgcttaggg tagccagcca tgagaaagcc aagggcaagg
    52021 gggtgctggt tgtgatgaat gatgaaattc atgccgctaa gtatgtcacc aaaacgcata
    52081 ccaccaatgt ttcgaccttt caaacaccga ctcatggccc tttgggagtc gtcatgaagg
    52141 acgatttact gttctttaag actgctgagc caagggttcg ctttgagctt cgtcatattt
    52201 ctggcacagt tccgattatc aaggcctatg ctggtatggg agatggaagt attttaagcc
    52261 ttttgacacc tgataggatt cagggactag tgattgaggc cctcggcgct ggaaatgttc
    52321 ctcccctagc agtatctgag ctcgaaaaat taatcgcctc tgggattcct gttgtcttgg
    52381 tctcgcgctg cttcaatggc atagcagagc cagtttatgc ttatcgcgga ggtggtgcca
    52441 gcttaaaaag ggctggtgtt atgtttgtca aggagctaaa tgcccctaag gccaggttaa
    52501 aattgctcat cgccctcaac gctgggctta caggtcaaga gctgaaggat tatatcgaag
    52561 gctaagctct cctataatca caggctacta ctcctcatct atagcacaaa aagcacgact
    52621 cggtcagcta agaacctctt gtcgtgtttt tatattagct ctgtccagca agtcagcctc
    52681 acatctaatc aaactgatca gcgacacgaa gattagccaa aatcggagcc catctagggt
    52741 ccagctgcca atccttagct gcaacaatct cagcagcgac tcgtcttgcc tcctctagga
    52801 tatgataatc ctctacaata tcagctgttt tgaactctgg caaacctgat tgacgggtcc
    52861 caaaaatctc tcctgagcca cgcagcttga ggtcagcctc tgccagcaca aagccatcat
    52921 tagtcgttgt catgatggtc atacgctcct tgcctgagtc tgtcttagga tctgccacca
    52981 aaatagcata ggattgcttg ctgcctcgcc caacacgacc acgcaactga tgcaattggc
    53041 taaggccaaa gcggtcagca ttcatgatca gcatgatggt ggcatttggc acattgacac
    53101 caacctcaat aacggttgtt gacaccaaga catcaatctc cttagcctta aagcgctgca
    53161 tgatcatctc cttgtcgtct gccttcattt tgccatgcat caaggcaaca ctagctgaag
    53221 ctttaaaata atccttcagc tcagcctcta aagctaccgc atttttcaaa tctagagttt
    53281 cagattcttc gatcaaagga gagataacat aggcctgtgt ccccttagca agctcggtct
    53341 ttacccaggc cagcacacta tctaattgcc gatgcttgac ccagcgagtg atgattggct
    53401 ttcgccctgc cggtaattca tcaataatgg aaacgtccat ctcaccatag gcagttatgg
    53461 ctagggttct aggtatggga gtagctgtca tcatcaaaac atctggattg ttgccttttt
    53521 cgcgaaacaa gcgacgctga ttgaccccaa aacggtgctg ttcatcagta atcaccagcc
    53581 ctagcttatg ataggtcact gcgtcttgga tcaaggcatg cgtcccaaca atcatatcca
    53641 cagacccatc agcaatagcc gataaagctg ctcttttttc agctgctttc atacccgatg
    53701 tcaacagggc aatagacaaa tctggaaaga gctgacaaag actatcgtaa tgctgctcag
    53761 ctaaaatctc agttggcacc atgagtgccg attgaaatcc cgctgtttgg gcagcataca
    53821 tggcaaggct tgcgatcact gtcttgccag agccgacatc cccctgcaac agacggttca
    53881 tatgagcccc tgaggtcata tctgctaaga tttcctccag gcttctttgt tgagctctgg
    53941 tcagtgaaaa gggcaaagca gcaatctttt ttgccactgc ctgctgatga aaaggaatcg
    54001 ctaacccatt gccctctgcc ttgttagcaa gctttaaaac ctgcagattc atctgaaaat
    54061 agaaaaattc ttcaaatttt atacggcgca gggcctgctt ataatcctcc atatgtttag
    54121 gaaaatgcat ggcataaaca gcagcttgtc tcggcagcag gcggtatttc tgaatcaagg
    54181 gctctggtaa attttcttcc agctgagcta aggcaccgct atcaaaggct gatctgatcg
    54241 ccttaatcag ggtgggttga ctgatcccct gcgccacatg ataaactggc tgcaaatcat
    54301 cttctaaggt catgagcaat ttcatacctg tcaaggctgc ttttttttga tcccacctac
    54361 caaagatagc cacttcctga tccaagacga ttttctcaag cagataaggc tgattgaaaa
    54421 agctgacact aatcacaagc tccccctgct tcaatttaaa gctcaggcga ttacgcttga
    54481 acccatagta ttgaacgctt ggtggagtca caactctacc tgtaaggaca gccttttcac
    54541 catctaaaag ctctaaggct gacttgcttt taaaatcctc atagcgaaaa ggataataga
    54601 gtagcaagtc cttgatctga taaatgccta atttttgaaa tttctcagct gactttggac
    54661 caagaccctt caaattagca atcgaactct ttaacagcat ctcaacctcg ctttcttttt
    54721 cattattata tcaaaaatca agagcctctc caaaaaggaa gaggctcgtt ttcttactgt
    54781 agatgccttg aggtattagc cgatcctaac acacccttag tgcggccgct aggacggcct
    54841 aactaaaaga tgaagagtgg catataaaca atacagcact gcttgctagg ccaagatatg
    54901 ccctagaatt gtgatagcta ctgctagctt gtcaagagtt ggcggcttgt gattggtcaa
    54961 tcgcagctag tggttatcag atcaagcagg aacacctgct gctccaagga gcgataaagc
    55021 catcaccaat acagcaccag accgcttgag caaggctagg cctttacctg ctcaactgat
    55081 agatactatc acaggcttga tccagtaatt cctcgtcatg agagatgaca atcactacct
    55141 ttttttgctg ctttagctcc tttaaaagac taaccagagc ctgcatttgc agcagatcta
    55201 agccactgct tggctcatca agaatgacaa tctccttgtc agacaagagg ctggcagcaa
    55261 tcatcaccct ttgctgctca ccacctgata ggctggcagg gtgcttgtct agaagctgag
    55321 aaagcccaag cctattcacc aaatcatcag tagcctgatg tctatgatga cctagattaa
    55381 gctccttttc taccgtctcc gaaaatagct gtagcccaac gtcctgcaac actaggcttg
    55441 tgattgaaag cctgtcctta gcaggcaggg tgacacccag atagctgatc ttggcctctt
    55501 ttgcttcaaa aatacctgcc agatataaag ccaactgcga ttttcccaaa ccgttagctc
    55561 cggtaatgcc agtgatttgc cctgcaccaa agctgagctg attgaggtga tacaaaaccc
    55621 tgctgcctgc cttgacctct agctgcttga tttgcaaggc atgctctgga tcataatgct
    55681 caaaaacagt ttttgcccgc aaagccttag tcacagcagt caactcacat cgtcttagtc
    55741 ctagctcctc acgttcctga tctggcaaag ctagcagatc cttggggctt aatacgcgct
    55801 ctagcctacc agctgaaaaa tagtaaaaat ggtctgccaa atccagcaaa taatgcaagc
    55861 ggtgctcagc gacaataatg gttttgccag cagccttaag ctgctttaaa taagccttga
    55921 ccgctgctac actagcatgg tccaaattgg ctgttggctc atcaaaaacc atgatagctg
    55981 tcccttgcat gatagctgct gcaatagcca cccgctgctt ttgaccacca gatagcttaa
    56041 gcatatctgc ttctagtaag tccttgatgt caaaatcagc tgccaaggta tccagcctct
    56101 caaggataag agctggctct aagccttgat tttcacaagg aaaaacaagc tcatgcttga
    56161 cctcacgata gaaaaattgg ctggctgggt tttgaaagac agaggaaacc tgccttgaca
    56221 gcacttcaac actagcctga ccagcctgat gagacagtac tttcagactt ccttgtaatt
    56281 gtcctgaaaa atagtctgga atcaagccat tgagcagctt aagaaaggtt gacttgcctg
    56341 agcctgactg accacaaagc acgataaatt gacctgcctc tatctgacaa tccctgagct
    56401 cacaggcagt ctgcctacga ttggtatagg aaaactgcag ctgctttgcc ttgatcactg
    56461 gagaaccatg taggctatcg tcacaaatat ccaaatctgt accccccaat ccttccatga
    56521 tagatgtgat acgaagcact cacttgctcc ctttttgatt gctagccctt ttgttaggct
    56581 agcaatggtt aagtcctgac tacttctcag caatgacatc aacagcggta ccaagagata
    56641 ctccatatac cgccttggct gtctgacaat agcccagctg tccaagaaaa tgcccctgat
    56701 tttcagagat tgccgaataa tctttccttc ttgcctgatc ttaggtaaaa aacgcagcat
    56761 gacagcaaga gtcaacagac aaacctctgg cacatgccat tttcgcagcc catgcacaag
    56821 ctcgtaggca gtcgttgtct tgacaaaaat caaagcagca agcacagatg ggtaaagcaa
    56881 ttgaccagca acagctgcaa agctcagcag cctaaacaga taggctggca gcacatgaag
    56941 cggcaataca gacaaagcaa gcagtaaggc atagagcagt gtcataccga ttgccagacg
    57001 cccttgacca agccaaaaca aaatgccaag caaaacacct ataatcatcg tccccagcca
    57061 gccatcaatc cgaaaaaaga agcaggcatt ggctagaatt aacaggagca attttgtgcg
    57121 aacatcaagc ctcataaaag cattcctgac ttagcaaaat gctttttcag caggtattga
    57181 ccaaaaaggc cacctactaa ggcacaaaga aggacaacac caacaaacca gctaacattt
    57241 gcaacggtaa agtcatacat gatacggtta acatatgcca tgtccttacc acgcgctaaa
    57301 agactctgga tataggcgtc cttcaacagc cacattaaaa taataggacc actgttaaca
    57361 aaggcaaaaa caagataaga caagagattc actagtctag attgatattt tcctaaaagg
    57421 gctatgccat ctgccaaaca gccaaaaaga atagctggta gcattgaagc aaaaaaatga
    57481 cctgtcaaaa agaaaaagct tcccataata attcctacta ggcttatcgg tccaaaggtc
    57541 tgcagcttag cgattaatag catataaact ggcccgccaa gcaaggccgc aaaggctggc
    57601 gcatagagca tattgcctga gcgatcaaac agaatgctca gcatggctcc tagccccaca
    57661 caaacgaaat agagggcggc aaaggcgcct gttgtcatga tatctttaat ggttaaccct
    57721 ttcattgttt acctccttca aaaaaccatt tctcacacaa aatagctggt ctgcacaggc
    57781 caaggtggat ggccgatgtg aaatcaaaaa gaccattccc cggcaatgct ttttaatcaa
    57841 atcaataaag atggcttcat tcagcgaatc taagtttgat gttggctcat caaaaatata
    57901 gcaatccgcc cgcttcaata gagcccgcat caattccaag cgctgggctt caccagctga
    57961 aaagtctgct gatcctctca ctagggtatc tagcccctca tcacaggcta ggatacgctc
    58021 cttcatgcca caggcctcag caagttccat gatatcatca tctgaaatgt ccttacgacc
    58081 aagtgtgata ttgtcacgaa gtgtttgctg aaatagctgc gcattctgtg ggacataggc
    58141 aaagttagcc tgtagggaag cagcatttag cgtttgactg tcaacctcac tcaggaaaat
    58201 atgaccagct tgccaattgt accatttcat aatgatcttc atcagagttg acttcccaga
    58261 gcctgactct ccctgaatac cgataatgcc tttcttttca aaagcgacgg ataagtggtg
    58321 gtaaatagtc tcctgatgct tgggataagc aaaggtcaga tcctcaacag caatccttgt
    58381 taccgaggaa atacgctgat ctcccttatc tactaacgct tcttcatcta aaagctgaaa
    58441 gacattccta gcagcattca tggcacgctt gaagccaagc ggcaaacgcc ccaattctaa
    58501 aaagggtgca aaggaggctg taaaggcaac aaaagccagc aacccaccag caaacgtcac
    58561 cgtctgctga ctcagctcaa aaagagtaac ataagcaaag gtcaaaatag acaagccaag
    58621 agccaaaaag gttatcgcca tttgtaaaaa ttgagcctgt gccacctgac gatcaagcgc
    58681 attaacatgc ttgctctgat tggataagag cttaaagcgc ttctcaatgc tttgaaattg
    58741 cagcaaatcc ttaacagatc tgagactctc taaaaagctt gacacataag ccctgcgccc
    58801 ttcattttgc tttttgagca gtgattgaag gacgtttgaa aaatacactg gaataataac
    58861 agccaaaagc acataggtca caatagcccc caaggctaac ttccagctaa cctgccaaag
    58921 gtaataggcc atcaagctag ctgaaataaa cgccgtacaa ataggggcaa gcgtgtgggc
    58981 aaaaaagacc tccaaggcct caatatcctc gccaatcatc tttaacaggt gcccgctgtc
    59041 ctgactgtct aagcgtgccg gcgagagtgc tcttagcttt ttaaagacaa tcctgcgaaa
    59101 ggctgccagg ctatgaaagg caacaaaatg cccaaaataa tgctctccat aacgaacaag
    59161 cccccttagc agtgccatag caacaaatag ataaagccat ttaaaggtaa tagcatgacc
    59221 agccatcacc tctaagccca gataggctaa gctggtagga atgccaacgg taagcacaaa
    59281 gcccagcact gcaaacatca ccgccagagc tatccaagcc agcaaatgct tcatcatagc
    59341 aagcaatcgt aaaactagcc ggtaggtgct gtaatcactc ttaaccataa agatttgcct
    59401 ccaattctac ttgtgtatca actaattgac gataggccaa atgatggcgg taaagctctc
    59461 ttgggctagc caagctagca gactgctcag ggcttaaaaa gagcacctga tcagcctgct
    59521 tcaaatattt catcttatga gtgatgacaa ttacaatggc ctgtttagcc aattgctgaa
    59581 gcagtctgtg aatagcagct tcattctcag catcaagact tgaggtagcc tcatcaaaaa
    59641 tataacagga acgctggctc aataaggccc tagcacaaat cacctgctgt ctttgccctg
    59701 cagataagtg acagccattc tcacctacaa tggtatcaat cccatcaggt agccagtaaa
    59761 taaagctcaa aatgccatgc tcatcaatcc agctaagcag ctcctttcta gtcagctgag
    59821 ctgccatagc aaggttctca taaatactca tattaagcag cgttgactgg tcagaaacgt
    59881 agagtatttc ctgattgatg gcctgtttag aagccagatc aatcgtcaca tcaccaagga
    59941 atatctgacc gctatctgcc tgatagcgct tcaacaggag ctgtgcaaga ctagtcttac
    60001 cctgtcctga aacacctgca acagctgtta gctcaccctt tttgatagtc atcgtgatgt
    60061 ctcttagcaa agccttttcc ccatgtgaaa aggacaaatc ttgaatatca atacgatcaa
    60121 aggccggtaa ggcaactccc ttgtcttggt caacagcctc aacactatct aaaaagccaa
    60181 agatttgatc tgccatttta gtattcatca tgactaggtg catgccatag ccctgctccc
    60241 taataggggc aaaaaattcc gttgcaatca ggataaaaaa gagaaagtca aaaaaggata
    60301 taccaccagc tgacagagcc tgaaccgcta aaaagccaga taagccaatg ccaagataca
    60361 tgacagcgtc catatagcca accgcttgca gctgaaagcc caagagctgc atggtagcct
    60421 tacgaaaggc ctctgcctta ttgacaaagc tttcctcata cctttcatct gcctgatagg
    60481 aataaagggt atttagcccc ttgagatcgt ccataaatag attgccaacg tccatatagg
    60541 ttgaccagta atggttcatg atccttttag agcgtttttg catagcaaca atggatatgg
    60601 gaatcaaggg caaagacaag ataaagacca agccccctat aggatagatc aaaaaaacaa
    60661 gcagtaagac cgttgtgcaa ttaaaagctg ttagcattgc aagcgatagg taataggaat
    60721 aataggtatc caagctatca atcccttgtg aggcaaccgt taacacatca gcctctgttg
    60781 actgctgatc aaattgcccg tccatagcaa taaaggcatc aaaaaaggat tgcttgagcg
    60841 agtcacgcgc aaattgcgaa gctaggccct gcagctgctt tgcaatcatc gccaagccaa
    60901 agccaacagc atttaaaatc aaaaggataa caagcagcct tgtcaattgc agggcttgac
    60961 ctgctaaaaa ggctgtgaat tgcttagcaa ttaagtaaaa gctcattaaa cgcatcaaaa
    61021 attgcagcca agataaaaag gccgacacat aaagcaaaaa acgcttagga gcaatacgct
    61081 cctttaaacg ccttaaaagc atttttttct ttgcgcgtga tattttttca gttgtatcgt
    61141 tcatataatc gtcgccttat tcctatctat cattcatttt ttatttgtct cataaagtgg
    61201 taagaacaaa tcgcctatcc tgcttttcaa taaagggcaa gctcacccca aaaaccgcct
    61261 ccacaaaagc ctgatcaaga acctcctgtg gactgccttg ggcatagatg gcaccttttt
    61321 gcagcccaag cacacaatcc gaaacagcca aggcctgatt aatatcatgt aacaccatga
    61381 taatggtcat tcctagctcc tgattgattt ttttgatgag ggctaaaatg tccagctggt
    61441 acttaatatc aagataagtg gttggctcat caagcactaa gacacctgtt ttttgggcaa
    61501 gcgccatagc aatccagacc ctttgctttt caccaccaga tagctcctgc atttccctaa
    61561 aggccaattc ccttagatta gtcacctcta aggcccaagc aacaatgtca tcgtcctctt
    61621 gacttgatcc cttaaaaaaa cgccgatggg cttggcttgc cacagccacc aaatcaccca
    61681 ccagaagatc tgctaccgcc tgattatcct gatgcacaac ggctactttt tgggcaaact
    61741 gcttaagact aatagagcta atagcttgtc cctctaagaa aatttgccca gacttaacgg
    61801 ggatattttt agtcagcaga cctagtaggg ttgatttgcc acagccgttt gcccccatga
    61861 ttgtcgttat cttgcctttt ggaatggtaa agctcagcct atctaaaata ggcctatcac
    61921 gataagtaaa ggacaaatcc tctacacgaa tcaagccttg ctcatgactc atatcacgtc
    61981 agacctcctt aacagataaa taaaataagg tcccccgaca atgctcatga taacagctgg
    62041 gctaatctcc aagggataac acaactgcct tcctaaggta tctgccagca aaaagacaaa
    62101 ggcgccaagc agggcagaaa aaggaatgag atagctatgc ttactgccaa ctaaaaggcg
    62161 gccaatatgc ggcacaatca ggcctaaaaa tgacaccaca cccacaatcg aggtggaaac
    62221 agcagctagt aagaccgcaa ccaacgagat tcctaagcgc aggtaattac tatcaatgcc
    62281 taaattacga atcaagccat cgtttagcag cagtagatca cactgccttg ctaggcctat
    62341 cgcaagcagc aggccaagca ctgtataagg ccacagcaca ccaacatctg cccaggtttt
    62401 ttgactaata tttcctgaca acagcgcatt gacaaaggga ttgctggttt ttgaaaaatc
    62461 agtaatcgca cgagacaagc ctaaaaacaa ggcgttgata gctattcctg tcaaaatgat
    62521 gcgtatcggc tgcaagccct tcttccagga caaggtataa atcatcaaaa aagaaacaca
    62581 gcctcccaca aatgataaca aaggaccata aaacaagagc tgcggcaaaa gcaggctaga
    62641 taacaagacc ataaagctag ccccactgca aaccccaata atcgccggat ctgaaatagg
    62701 attttttaaa atcgcctgaa acaagacccc agatgttgct atccccgccc cagccaataa
    62761 agcaatcaca atccttggaa agcgtaaatc gtaaataagg gctacctctg aatcatatgc
    62821 tacaaataag ccattaaaga tcctctgata agaaacagat aagcccccaa cagagaccgc
    62881 atatagcatt aaaccaaaca gcagcatgag caatagaacc atatagacca gtctagtggt
    62941 cctttttctt gctgctgtga cttgatcaga atattgacta ccttgctgca tcttacttga
    63001 cttcctttgc tccataaaag atttgtgaca gatggttcaa agcctctttg tagttaaact
    63061 tagcactcat gccaaaaagg gtattgtcta aatcataaac ctgctgagac ttgacagctt
    63121 caaaatgctt ccaaatatca ttttcagcaa attccttatc aaacatgtcc ttaaccttgt
    63181 ctggaatggc gtgggcagta cgcaaaatca gctcaggctg ctgctgaagc atgtcttctg
    63241 gattggcaga caaaaattcc ttgtcctcag agtgataaac attctcacca ccagccagct
    63301 caagcagatt accaacatag gatttatttg tagcaatcag atagctgcca ggaagcccca
    63361 tcaaaataag aaccctaggc tttttttgcc ctttatgctt tttcttaaag gcccggtaaa
    63421 actcctcata atcagcccgc aagcgcttag cttccttttt gcgatcaaac aagtccccca
    63481 aatcatcaat cgactggtac atgccttcaa ggctagttaa attcaaaaag ccatattccg
    63541 tatccaattg ctggtattta ggctctaaat cattttgcag agaattggga ctgagtatcc
    63601 acgttggctt tagagaagca ataacctcca tatcaggatt catcggcaga ccgatccttt
    63661 tgacagcatc gtaacgcttt ggcaattggt atagcttact gtcacagacc ccaaccaaat
    63721 ctaggcttag ccgatcacaa atatcaacaa cagccacaga ggtggcaaca attctctcct
    63781 tatcagcctt tttctctgcc ctagggtgct gatccacaca agcagatagc accaaggaca
    63841 aaacagctaa tccaataagc ttaatgactt tcttcattgt tttttctctt tttctttata
    63901 aacaagacca aggctcctga caacaaaaga gctgttggta catagtaaac cagaactggc
    63961 aatggattat ttactggctt ttgggacgac tcttgcttac ttttatctag cgaagtgctc
    64021 aaaccaactg cctgaccctt cttagaggga tttgactgtt ttttgggact gcttgattga
    64081 ccaactggcc ttgctgaggg attaggagct gacttggcgt cttttgagtc cggtttacta
    64141 ggagctttct tctcatctgc ctttgcagga gctgtcaccg catgatccgt cttggcttct
    64201 cctgctgcaa agctagctac catatctcca ctgtagcctt cttgtagctc agatggtgac
    64261 aggtaaaaga caacctctct gcccataggc tctacgtaca tgctgcctct aacaaccgta
    64321 ttgacatcag gcaaagcaat cgcaatatcc tttgttgtgc cattggtatc agtgccaacc
    64381 ttggtgacac tgtaggctgc cgcctgaaaa gcccctgtac cacccggctg aacccaaaat
    64441 tggtagttac ctgaaaaatc agctagactc atgcgaaagg tcagatacaa atccccagcc
    64501 gaggttacct ctagcatacc attgctataa actgttcctt ccaccatacc ttggccaatc
    64561 tcaaaagcgt gctcaccacc gctatcttca atttgccctg aaaccgggtg acgataatct
    64621 cgcctaatca cacaggaata aagctcaccc ttatcagcat aggccttacc tcctatagct
    64681 gctaggcaaa ccagcaatac caccaagcca cccattaatt ttttgaataa tctctttatc
    64741 atatgttcct cattaatgat cttcatttcc ttacgacaat caaataaggc atagatttag
    64801 acgcaggcca agacctactc ttatttgact attataacac ctcaaatacg aaaagcatac
    64861 ccattcctca cttaccaagg gtaagcttaa gaaatcatta gaaacaggca tgcctttacg
    64921 tatcgttgat aagccttgat gactacaagc gattaaacca agctcttagt gcatcaaaca
    64981 gactctctac tgacttaaaa taattttttc ctaccaagaa tgagaccaac tgctatgaca
    65041 ataaagcttg ctagaccgat aatgatatgg ccgcgatgat cagctttcat ctgctcctga
    65101 ctatgtttag cagccttaga tttagctttg gctctagtct tagcagcctg cttagaggcc
    65161 ttgcctgtac cagccttaga cgccttatgt gaagaaatca ggctcttaag cttatctgta
    65221 ccggtcttag cgtcctcctt ggcattactg cttggagcag ctgacttctt agtcaaaaga
    65281 ttggtcaaat taggaatagc aggacttgta tgaccaccaa tgatacctgt gtgaggctgc
    65341 aagagctcac ctatggtacc atgtccctga ttgtcctctg agtgtggcaa ttgtgcctta
    65401 tcctttgtca ggctttgaag atccaacttc ataaagactg tctggaagcc tgttccctta
    65461 gagatagcgt ccataattgg cacaaagacg cgaagaggta ccaagccatc ctttttagcc
    65521 tgatcaatca gcctaaatct caacacctgt gggtaattgc tgccataagc gtctgacagg
    65581 ggcttgcctg tgacatctgt aaagtaggac acaacctctg ctttttctgt cttaccaacc
    65641 ggtctgccag tcaaatccct ttggtagcca tcaacaaagt agctcaactc tccgagatac
    65701 cctgtcaggt taccgatctt catgccctta aaggtcacct ctaggctata gacaccctta
    65761 ttcacaatca atttgacgcg gtggtcaata gcctgatgag acattgattc tgactgcaaa
    65821 tcatttttaa gcatgcttgc cttgatgtag tagacaccat cttcaagctt attaatatcc
    65881 aagcccttag actggtcact acctgcaagc tgatcctcct tgacctcaac atcattagag
    65941 gtcagataaa tatgctcacg cttcttagca aattccttgg tgataagagc cttacgaaca
    66001 cgataaacac ctgctccctt taggtcaaag gagccttgaa gctcatcttg tggatcgtta
    66061 ttcaagcgtc tctcatcaac ggtgacatat tgaccggttg atgttttttt ctgcaattgc
    66121 accacaatat cccagtcagc ataacgctca tttaataagg caatgatgtc tgacgagctt
    66181 gccttaaggc gtttattgta atcctcaaca gagctaattt ctgcttcggt gcttgagagt
    66241 gtctgctgct cccaataata caaatcaagc aggctaaacc cttggtgata ggtcatcgct
    66301 tgatgattta aagtcgcaga tagattagca aattgctttt gtgggtttag cttatttgtt
    66361 cccatgatct gtctaagctt atcactaacg ccacttaggc agttaaactt aagatcaaga
    66421 tccaatgcct ttagatctgc aaaatcagct tcgctaatat tcgttaaaag gttattatag
    66481 acattaagct ttgatagctg cttattagcc ttgaaggctc cctgtgggat tttagttagc
    66541 tcatttgatg ccaagtcaac ggttaataag tttggcatat gactaaagtc aatattagca
    66601 atatctaaaa cctggtttcg attggcaacg atataagaaa gcttagttag cttactcaag
    66661 gagcttggca ggctgcccaa ctggttttca gaaacatcaa agaagtttag attatcaagt
    66721 gaagctagag cattttctga aaattcagta atgatatttt cagccaaggc caaggaggtc
    66781 aagcgagata gaccattaaa gacaccatct cgaatcacgc tgattctatt ttttgacaga
    66841 tctagctgat ccagctgacc aagatttcta aatagtcctt cctccagatt tggcatatag
    66901 ttgcttgaga gatagagctc ttttagctgg ctgttatgag caaaggtatc cttatctagg
    66961 gttgtaatca cattgctgcg aagatttaag aaccttagat tggtcatttg actgaaggtt
    67021 tcctttggaa tgcttgcaat ctgattgccc tctaagtgca gctcagtaat atgcttagca
    67081 tgctttaaga gtgaaatatc tgtcaaatca tagtggtcta ggcgcagctc accttcaatc
    67141 ttcgcaattt cctcaggtga cattttgcca tcaccgttaa ggtccttacc aagcttaacc
    67201 aaaacctttt caagacgctc agagccgacc cctttttcct tgtcgtcaat ctcagcctga
    67261 tagcctgtcc agcccttact tgctgtagcg ctaaaggtca tgtccaactt ggtgtatttg
    67321 tcatagtgat gtaggtcgct ttcctgacca cccatagctg atactagcac agcacccttg
    67381 tgaagcttgt ccagctcctc aatcggtagg gtaaattcac tctaatgtag ttattgttaa
    67441 tatcgcgttc accaacctga gtgcggacag aggttggata ctgcccttta ctctcaatgg
    67501 aaaagtcaat caaaaattgc cctagagctg tattgagcaa tgaaatctcc atcttgccat
    67561 cttctttgac gaccagcttg gccttcttat caaatgctcc ctgcagcatt gaggcttcct
    67621 ctgtattttc cttattggcc ttaaaggtta aggtataggt tcctgccttt agatccgtaa
    67681 cagccagatc agttccctga taggacttga tactatccat caaaagctca taggtctcct
    67741 tgagcaattt ttcattgtca atctgacgat aggactcctt gatcacctga agcttgctag
    67801 acaagtcctt gacctgttct ttattggcct cgctagcaat gatacgctca gcttccttga
    67861 tcgcgctttc cagcttagta aaatcaagtc cctgcggtgc ttcctgctgg gatccttgtc
    67921 tctgcttttg cttagcagaa acaaaggtgt attgctcccc tgactttttc actgtaatga
    67981 tgacatcttc aaagctttgt gaggaaatga caaccttgtt ttctccctcc ttgaaagctg
    68041 tcgtcccaag atgaagcccc ttcaggtcag acacatagcc aggcttgtcc tttactgaat
    68101 catagaccaa atccttatag tcctggtcat tgaccttgat ctttgtgatt tgatgagcta
    68161 attccttaat ttgcttggtg ctggaatagc gatcaatttc cggaaaaaga agctctcctt
    68221 ctgttgtctc tagtttggtg ataaatgata gggtcgctaa gccatcatgg ctagttacct
    68281 tagcaggctt ttctgtctta gcagcagctt gctgcggtga agcagtagta tcatctgaag
    68341 gcttggcaga aacaaaggta acatcatttc ctttcttgtc aaagaccaca agaatgcctc
    68401 cgttagtctt attgacgatg cgcagctgat gctgtccttc tgtgatgttc ttagcgttta
    68461 ccttgattcc ttggtaattg atgtcatagc tatagtcacc ctccagcttt ttgtcatact
    68521 ctttaccatc aatgagaatt ttctcgatat ttttataata gagcttcccc tctgacttgt
    68581 ccgcataggg accgatctcc tcgaacaata aaatattatc cttaagcttg acagtcgtca
    68641 caagacttga agagacttga gtagcctctg agcgaaccgt ctgggcagac tgggcaagag
    68701 ccagcgttga taaagcaaga atggcgcact tattgatact tttcattatt tcgaaccttc
    68761 taaaaatgtt attagccatt taattatttt attaatctca cttaatttat tatgttgtca
    68821 agcctttgtc aagattgaat ttgagatttt tttcacaata aagcaaagaa aaaaacagcc
    68881 ctgcaacaga gctggatttt ttcttacaaa aattctgtac ttctcgcctt taaagcaaga
    68941 agattactta tgattttcca acaacataag tcaattggtt ggcctgctca gcagtaaagg
    69001 tgcggtatga aatctgacct aagccaagac aatttgactc tgaaatcagg atggagccgt
    69061 cctttctgac atcctcaaca atagagacgt gcccataaag accgtcagca cccgcttgac
    69121 ctggagcaaa ggaaaccgca tagcctacct ttggctcctt agaaatactg tagccagact
    69181 taaatctcca gtcaccacca tttcccataa aggaatcaaa ctgatagcct agctccttag
    69241 cgcgattata aacataccag gtacattgtc cccaagcata gcttgacgcc tgatagctta
    69301 aaatatcata gctcttagac agcttgtagc ctgtaggaac aacagcaaag cttgaagagg
    69361 attgaatttt cagctcagcc ggaatctctg gcgtgcctcc atgctgatca atccaagcat
    69421 ctaatttttc catgatctca gcgcgacgct tgccaatgcc attggtatct gtgaagtaaa
    69481 gaccaccatc actagcaaag ttcaactgct ttttggcaaa tttatcagcc ttttgatcct
    69541 gctgctcaaa attaaggttg ctatttttga taatcgtctc ctgtgtcagc ttaacaatag
    69601 caagctcatc attaaactga tttggctttt tcgaatcaag gtcaaaaagc gcatagccaa
    69661 acatgttaga gcctagtaag gttgcatttc ccttggttcc tagctcactt tctgtcattg
    69721 caatggctac aatcgcccgc acatctagcc cactcttttt ttcccattgc agcaaggcag
    69781 caccgttaat tcgcttctca tcatacttga tcttggtaga ctttaaaaag ctatcaagct
    69841 gctctgcctt gatcccatag cgcctagaca agaggttatg ggtataagca ctctgaccac
    69901 tccaatgcgt cacataagca gcataggtat ttacagaagg cagggccaga gtcaaggaca
    69961 aatcaactgt aggagcagca ggaacaatat tcagtgccgg ctgagatgcc tgtgtagcaa
    70021 cttcaggggc tggctgaggg ctagctgctg gactagtagg tgtcgactgt ccagtagaac
    70081 cagaagctga tccagagcta gctgtattgc ttgatgaccc cgttgctcca ggttctccac
    70141 tgttgggagt agtctcagtg gttgatgagg agttgtcagt agctgaggta gcagctgctg
    70201 tcgaagtgga ctcaccagtc tgggcgattg cagcctcatt agcagtagct ggaacctggc
    70261 tggcttcagc tcctgtatcc tctgccaata ctcttgcggt ctctaaatga ggtaccagaa
    70321 gagtcatcag cattatcatt cttaataatt tattttttct catttagtat tcaatcactt
    70381 ctttctgctc tattctaacc tacattataa cattgaagca aaataaaatg caagattttt
    70441 tgtattaatg ccttaatact cggataaagg taagggcctt ttctt
//
LOCUS       DARYLD010000003        56683 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYLD010000003 DARYLD010000000
VERSION     DARYLD010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56683
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(140..505)
                     /gene="rplL"
                     /locus_tag="TU651_000146"
     CDS             complement(140..505)
                     /gene="rplL"
                     /locus_tag="TU651_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL0896189.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(570..1070)
                     /locus_tag="TU651_000147"
     CDS             complement(570..1070)
                     /locus_tag="TU651_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL0896190.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(1099..1234)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(1366..2007)
                     /locus_tag="TU651_000148"
     CDS             complement(1366..2007)
                     /locus_tag="TU651_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL0896191.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(2004..2771)
                     /locus_tag="TU651_000149"
     CDS             complement(2004..2771)
                     /locus_tag="TU651_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL0896192.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(2771..3523)
                     /locus_tag="TU651_000150"
     CDS             complement(2771..3523)
                     /locus_tag="TU651_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL0896193.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(3534..4664)
                     /locus_tag="TU651_000151"
     CDS             complement(3534..4664)
                     /locus_tag="TU651_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL0896194.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(4731..5417)
                     /locus_tag="TU651_000152"
     CDS             complement(4731..5417)
                     /locus_tag="TU651_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896195.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(5451..6803)
                     /locus_tag="TU651_000153"
     CDS             complement(5451..6803)
                     /locus_tag="TU651_000153"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL0896196.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(6856..7812)
                     /locus_tag="TU651_000154"
     CDS             complement(6856..7812)
                     /locus_tag="TU651_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL0896197.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(7809..8660)
                     /locus_tag="TU651_000155"
     CDS             complement(7809..8660)
                     /locus_tag="TU651_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL0896198.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            8762..10105
                     /locus_tag="TU651_000156"
     CDS             8762..10105
                     /locus_tag="TU651_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL0896199.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            10105..10893
                     /locus_tag="TU651_000157"
     CDS             10105..10893
                     /locus_tag="TU651_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL0896200.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(11517..12506)
                     /locus_tag="TU651_000158"
     CDS             complement(11517..12506)
                     /locus_tag="TU651_000158"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL0896201.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TU651_000159"
     CDS             complement(12748..14517)
                     /gene="lpdA"
                     /locus_tag="TU651_000159"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL0896202.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(14726..16135)
                     /locus_tag="TU651_000160"
     CDS             complement(14726..16135)
                     /locus_tag="TU651_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL0896203.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(16259..17257)
                     /locus_tag="TU651_000161"
     CDS             complement(16259..17257)
                     /locus_tag="TU651_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL0896204.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(17337..18305)
                     /locus_tag="TU651_000162"
     CDS             complement(17337..18305)
                     /locus_tag="TU651_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL0896205.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(18811..20721)
                     /locus_tag="TU651_000163"
     CDS             complement(18811..20721)
                     /locus_tag="TU651_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0896206.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(21131..21916)
                     /locus_tag="TU651_000164"
     CDS             complement(21131..21916)
                     /locus_tag="TU651_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL0896207.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(22022..23683)
                     /locus_tag="TU651_000165"
     CDS             complement(22022..23683)
                     /locus_tag="TU651_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0896208.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(23893..24651)
                     /locus_tag="TU651_000166"
     CDS             complement(23893..24651)
                     /locus_tag="TU651_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896209.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(24648..25517)
                     /locus_tag="TU651_000167"
     CDS             complement(24648..25517)
                     /locus_tag="TU651_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896210.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(25531..26526)
                     /locus_tag="TU651_000168"
     CDS             complement(25531..26526)
                     /locus_tag="TU651_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0896211.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            26878..28548
                     /locus_tag="TU651_000169"
     CDS             26878..28548
                     /locus_tag="TU651_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL0896212.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(28637..29875)
                     /locus_tag="TU651_000170"
     CDS             complement(28637..29875)
                     /locus_tag="TU651_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL0896213.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(29865..31046)
                     /locus_tag="TU651_000171"
     CDS             complement(29865..31046)
                     /locus_tag="TU651_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0896214.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(31109..31585)
                     /locus_tag="TU651_000172"
     CDS             complement(31109..31585)
                     /locus_tag="TU651_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0896215.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TU651_000173"
     CDS             complement(31763..32809)
                     /gene="rfbB"
                     /locus_tag="TU651_000173"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL0896216.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(33001..33597)
                     /locus_tag="TU651_000174"
     CDS             complement(33001..33597)
                     /locus_tag="TU651_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL0896217.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TU651_000175"
     CDS             complement(33597..34466)
                     /gene="rfbA"
                     /locus_tag="TU651_000175"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL0896218.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(34523..35632)
                     /locus_tag="TU651_000176"
     CDS             complement(34523..35632)
                     /locus_tag="TU651_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL0896219.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(35687..36475)
                     /locus_tag="TU651_000177"
     CDS             complement(35687..36475)
                     /locus_tag="TU651_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL0896220.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(36465..37151)
                     /locus_tag="TU651_000178"
     CDS             complement(36465..37151)
                     /locus_tag="TU651_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL0896221.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TU651_000179"
     CDS             complement(37225..37887)
                     /gene="nth"
                     /locus_tag="TU651_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL0896222.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(37887..38564)
                     /locus_tag="TU651_000180"
     CDS             complement(37887..38564)
                     /locus_tag="TU651_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL0896223.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(38631..39149)
                     /locus_tag="TU651_000181"
     CDS             complement(38631..39149)
                     /locus_tag="TU651_000181"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL0896224.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(39229..39597)
                     /locus_tag="TU651_000182"
     CDS             complement(39229..39597)
                     /locus_tag="TU651_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896225.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TU651_000183"
     CDS             complement(39606..41816)
                     /gene="recJ"
                     /locus_tag="TU651_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL0896226.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(41813..42577)
                     /locus_tag="TU651_000184"
     CDS             complement(41813..42577)
                     /locus_tag="TU651_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0896227.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(42577..43506)
                     /locus_tag="TU651_000185"
     CDS             complement(42577..43506)
                     /locus_tag="TU651_000185"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL0896228.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(43521..44159)
                     /locus_tag="TU651_000186"
     CDS             complement(43521..44159)
                     /locus_tag="TU651_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL0896229.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TU651_000187"
     CDS             complement(44152..45390)
                     /gene="hflX"
                     /locus_tag="TU651_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL0896230.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TU651_000188"
     CDS             complement(45475..46365)
                     /gene="miaA"
                     /locus_tag="TU651_000188"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL0896231.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            46498..46674
                     /locus_tag="TU651_000189"
     CDS             46498..46674
                     /locus_tag="TU651_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL0896232.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(46830..47467)
                     /locus_tag="TU651_000190"
                     /pseudo
     CDS             complement(46830..47467)
                     /locus_tag="TU651_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TU651_000191"
     CDS             complement(47624..49888)
                     /gene="glgP"
                     /locus_tag="TU651_000191"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL0896233.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMDGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TU651_000192"
     CDS             complement(49914..51416)
                     /gene="malQ"
                     /locus_tag="TU651_000192"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL0896234.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(51623..52645)
                     /locus_tag="TU651_000193"
     CDS             complement(51623..52645)
                     /locus_tag="TU651_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0896235.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            52892..54145
                     /locus_tag="TU651_000194"
     CDS             52892..54145
                     /locus_tag="TU651_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0896236.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            54445..55806
                     /locus_tag="TU651_000195"
     CDS             54445..55806
                     /locus_tag="TU651_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0896237.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            55806..56642
                     /locus_tag="TU651_000196"
     CDS             55806..56642
                     /locus_tag="TU651_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0896238.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        16456 a        13418 c        10674 g        16135 t
ORIGIN      
        1 aaaataaaaa ccctgccaaa aaatctttgg tagggttttt agcaggaaac caaatcaatt
       61 tatcagtttc tctaaatcgc tctaagcaat cattaaacct tgatttacta ggcttccgca
      121 atcaaattgc gatactctat tatttaagag tgatagttgc tccagcttct tcaagcttag
      181 ctttgatttc ttctgcttct gctgctgcaa caccttcttt gatgttagca ggtgcgccgt
      241 caacaagacc tttagcttct ttaagtccaa gacctgtgat ttcacgaact gccttgataa
      301 caccaacttt tttgtcacca gcagatgtca actcaacgtc aaatgaatcc ttagtagctt
      361 cttcagcacc accagcagca gctacagcta caggagcagc tgcagtcaca ccgaattctt
      421 cttcgatagc ttttacaaga tcgttaagct caaggattga agcttcttta atttcagcaa
      481 taatgttttc aatgtttaat gccattgtca tttcctccaa atagttatat taaataatga
      541 tttgtagctc taggctacct ctaaaggcct tacgcagcgc cttctttgct ttctgcaaca
      601 gccttgacag cgtatgcaac gttgcggact ggagcttgaa gtacagaaag aagcatagaa
      661 agcattcctt cgcggtttgg caatgctgca agtgcttgaa tttcctcttt tgaagaaaca
      721 acaccttcga tagcaccacc tttaatctca agtgcttcag cagttttagc aaagtcgttg
      781 atgactttag ctggtgcgat aacatcttca tttgaaaatg ctactgcaga tggtcctacg
      841 aatatatctt ttagctcgtc aagacctgct ttttcagctg cacgagtcaa gattgagttt
      901 ttgataacct tgaactcaac gccactttca cgaagtgaac gacgaagaac agtatcttga
      961 tcaactgtaa gaccacgtga atctacaaca acgatactta cagctgcttt cattttctca
     1021 gcgataagct caacttgttc agctttttta gcgataattg cttcactcat tagttttacc
     1081 tccgttttta tttttgggct aggcacaaaa aaatcgcacc taaacctaga cacgaaagta
     1141 caaatacgtt atcttcaata atgacgtttt gtgcctcggc aggaatatta tgagcacgct
     1201 cccctgctgt cttaggtcag ttttattcaa aaccatagtt agtatagcct ttttaaatga
     1261 ctttgtcaac ctatttttta gaaaatctta aataaaaaag gaaagctctt ggctttccgc
     1321 taaatagatc tgattagtgg ctcaaaagcg cctcctaact taagcctaat gataagcaac
     1381 ttgtgacgat tgattgctat aacttagccc gatcaagctc cacagtatca tctcataaat
     1441 aaagaagaac aaggcaaagc aatgcccaaa aaaggcctct ggcaaaatcc aaatgacagg
     1501 atctgtcagc ggatcaaaca accagcttga atctcctaca aagagaattt gatgaaaaag
     1561 ggtaaagaac tgatcaaagc caatcattaa agcaaagcaa gcaatcacaa ttggcaataa
     1621 ggctgctgct attagccctc ttcgaagcag cataaccctt ccttttttga tgctctgata
     1681 aaaatagata atggttggca acataagcag gctaaagatc agctgtgtta tatgaaacag
     1741 cattttcaca tctgtaaaat gctttagacc agctcttgat gctgaaaagc tggctagctt
     1801 tagctcacga acaaaaggat tggttaagta agtcagcaat atattatagt tgtggagaat
     1861 agactttttg cacatcaaaa ctgcctgctc tagttgcaaa taatcaacct caatcggata
     1921 aagcagccaa gataaataga tagttatcaa aactgccagt gctagtagcc aaagccaact
     1981 ggcaatgaac ttgccttttt caatcataat agctcccact catctaagct agccaagaca
     2041 tgatcaggct taattggaag gcttggaacc tcttttgcct ttgtaaagcc ggttgttact
     2101 agaatagttg ccatatcatt ttgaattcct gccatgatat ctgtcaggta attgtctcca
     2161 accatagcca cctcagaacg tggtaccttt aagatctcta gggctttatt catgataatc
     2221 gcatttggct ttcctataaa tactggcttc actctagttg ctgcctcaag gagcgcattt
     2281 aaagcgccag cacctggcat tagcccacgc tctgttggaa tatttaagtc aggattggtc
     2341 ccaataaaca aggctccttt ttgaatggca agtgttgcaa ttgataacat ttcataggta
     2401 acctcagtat ctaagccaac aacaacatag gctggatttt ctgtatcctc ggtatagcct
     2461 gcctctgcaa tggcagactt taagccagtc tcgccaatca cataggctgt tttgcctcga
     2521 ttcatatcat tcatgtaatc aacggttgcc attgtagcgg tgtaaatggt ttcaagacct
     2581 gtatgaacgt taaattgatt ggctagcatt tcctgaacca tttcaggtgt tcttgtggtg
     2641 ttgttggtaa ctaagagata agggatacct ttttcctgta aacgcttgat aaagcgctca
     2701 ccagccggga tacgattttt cccttgatag atggttccat ctaaatcaat taaataagct
     2761 ttatagggca ctaatttgtc tcactttctt tagtcgttat aggctgccat ttgataatgg
     2821 cctgcgcatt aagctggcct gatgacctga tctcatggta ggaggtcaaa tgctctagat
     2881 gatagcctga ggttatttga gtgctgggcc tcacctcttt gatataggtc aaggtaaggt
     2941 ggcaaggtct gtggtgtaat aaaaattcat atcccaaaac gtcatacatc caatccaaat
     3001 acttactatt attggcatga ccattcatat caatgtcaaa ataacgaacc tgataagctt
     3061 gaaccatagg atcctgaagc tcatctattt tgataggacg cttgattttc ttaacaaagt
     3121 cagcctgata aggcaccacc aaatcatctg gtatcgcagc tgccttacgt gtttgaggat
     3181 ttagcagggc aaaatgagat aaaatggtca tgatggcatg acctgcctga tcataaatgt
     3241 gaaattgccg gtaacaaaat aatttattgt aagaaatagc ttgcgtttca atggttactg
     3301 tttccccaaa ccttggcata cgatcaatcg ttacatcata atccgtaaca acccaaatca
     3361 agccatattg ctgaagtaac acctcattgc ctcgtccaat ttcagctgat tgtcttgctg
     3421 ataccattaa gcaatgtgct aataaaaggg gcagcttgac atcagcctta acatcacaaa
     3481 aatcaaaaga cagcttaagg ctttcgctat accttaatcc cataacacac ctcctaatct
     3541 aagatgaatt tttcagcgac agaatcacct aaaaagaggc cttttttggt cattctgata
     3601 aagtccttgt cctctaccaa aagcccctga ttctgaagct ctctcacaac aggaccatag
     3661 cgtgactcaa atgataggcc aaatttttct tgaaaccgac tgactgatac tcctgatttt
     3721 tttcgcagac caagaaaaag ctcctcctcc atcatctcct ccttggtgag cacttcctca
     3781 cttaacctag catttccatc tgctactgcc tttaggtaat gctgaatagg aacccggttg
     3841 cggtaacgaa tcccatcaag atagccagaa gcccctgcgc cacagccaaa atactcatca
     3901 ttattccaat acatcagatt gtgcctgctt tcaaagccag gcttagtaaa attagaaatt
     3961 tcgtaatgct caaagccact ggcttccatt tcagaaataa tatactcaaa catctcagct
     4021 tccaaatcct cagtgggcaa atggagcttg ccacgacgca ttttgttcat aaaaacagtg
     4081 tgatgctcta ggataaggct atacaggcta aggtgaggaa tatctaaagc aagtgcctta
     4141 gccacatttt ccttgacctg ctgcatggtc tgtccaggca aagcataaat gagatcgata
     4201 gacatatttt gaaagcctgc ctccttaaga ctagcaatgg tcgtataaat ctgagcctca
     4261 gtatgactgc gtccaatctg ctttaattgc ttgtcattaa aagtttgaac gcctagggaa
     4321 atccgattga cagccgattg ccttaatact gcaatcttat cctcagtcaa atcacctgga
     4381 ttggcctcga tggtaaattc ttcaagctgg tctagctgta ggtgctgctg caaatggctc
     4441 agcaaataat caagctgatt ggctgttatg gctgttggtg ttccaccgcc aatataaagt
     4501 gtcttcaagg agctgatctg ataggattca aattccttaa tcagtgcctc taggtaggca
     4561 tcgacaggct gatttttgat aaatacctta gaaaaatcac aatagtagca aatttgtgtg
     4621 caaaaaggaa tatgcacata ggctgaggtt ggtttttttg acatggtaat attatatcat
     4681 tttagctcag aaattcatgc caagtgatta gctttttgac atgtactaac ctaaggctgc
     4741 ttctttttct ccattctcac aaaggaatga ctactcccat tagcatactg ctcaaagctt
     4801 gaggttggct gatagcccat tttttggtag aggctttgtg cgcctttatt aaagctagcg
     4861 acatttaaaa cataggtttc ttgcggataa gtagtgctag caaaggcttc aatgctgccc
     4921 aaaaaagaaa caccatcttc ctgaccagta gtatcagggg ccataccaag accaatctca
     4981 agctctgatt cctgttcaaa aaagctggca aagccaaaaa gaacaccatt gcgaagcact
     5041 tgaaagtaat gctctccacg cgccttgggt gacaatattg actgatagtc ctcaggatca
     5101 gcagtcatgc tatagcactc ataagctggg ctatagatcc agtcatgcgc aatgatttca
     5161 gcactatgct gtgtcatcgg catcaggtaa aaagaagact cagacaataa gcgatgaaag
     5221 gtcttgttga tatgctttat gcgacgccgc tgcacatcag gctgatctgt ttgataaatg
     5281 taattagcat agccctcctg atattctgga atcattgtca aatacagctt ttgggtcaac
     5341 tcatcaagct gactagcaat cctatccact ctatgcttta tcatattacc tccaattcta
     5401 atgctgcttg atagcataaa aagtgccgaa gcaacgacac tttttctaga ttaatcaagg
     5461 ccaatttccg cacgaacaac cgctgcaatg gtatcaacat aatagtcaac ttcttcattg
     5521 cttggtgcct ctgccatcac acgcaacaat ggctctgtgc cgctaggcct taccaaaatg
     5581 cgaccattac cagccatttc tccttccatc tgagcaataa cctcagcaat agcaggcact
     5641 tccatagcac gctccttcat gctgttgtca acacgaatat taacaagctt ttgtgggtaa
     5701 atagtgacct cactggccaa ttcggagaga gttttacctg tctccttcat gattttggtg
     5761 agctgaacag ctgtcagttg accatcacca gttgtattgt aatccatgat aatgacatgc
     5821 cctgattgct caccaccaag attgtagccg aactgacgca tctcctcaac aacgtaacga
     5881 tcaccaacag ctgttacctt cttatgaatg ccacagctat ctaatgcctt gtgaaaacca
     5941 aggttagaca tcactgttgt cacaatcgta tttttagcta gcaagccctt ctcagaaaga
     6001 tacttgccta tgataaacat gatcttgtcg ccatcaacaa tagcaccatt ttcatcaaca
     6061 gcaattaaac gatcactatc gccatcaaaa gccaatccaa tatcagaggc tgtttctgtc
     6121 accaagtcct gaagcttttc agggtgtgta gagccgatac catcattaat gtttaatcca
     6181 tttggattct caccaataac tgtaatgtct gcatttaaat ctaaaaagac attacgagct
     6241 gaaacagaag ctgcaccgtt agcagtatca agagctatct ttaaaccgtc taaatctgct
     6301 ccagtagtaa ccaagaatct ctcgtacttg cgcaagcctt ctggataatc aaccaaggct
     6361 cctaagccct ccgcacttgg acgtggtagg aggtcctctt tggcatctaa gagcgcttcg
     6421 atttctagct cttgctcatc agccaattta aagccatcac tcccaaaaaa cttaatgcca
     6481 ttgtcaagag caggattgtg actagctgaa atcatgacac cagcactagc cttttctgta
     6541 cggaccaaat aggacacacc aggagttgca agaacaccaa gcttatagac ctctatccca
     6601 acagaaagca agccagcaat cagggctgcc tctagcattt caccagagat acgggtgtca
     6661 cgagcgacaa aaactctagg cctttcagtc tcatgctgac ttagcacata accaccgaac
     6721 cgaccaagct taaaagcaag ctctggggtc aactctacat tagcctcgcc tcgaacacca
     6781 tccgttccaa aatattttcc cataatttat atcagctaaa cgcttcctcc attccatttt
     6841 cctagctatt atgctttatt ttttaattgt tgtcaactga acggttacta ccgaaggctc
     6901 tatagaaacc tgatttgaaa ccaagctgac cgttttgctc gtgtttttgg tgacgtcaga
     6961 aatattgacc tctgccacca cctcatcaat agtttcaagg acctcccgac taccagaaat
     7021 aacagcggtc tgcttggaga gcttatactg gatatctgac agactgtcat ccattagtcc
     7081 aactgcctcg actcgaatag gaactgattt ggtgattttt ttgacagaaa ctgacaaatt
     7141 agccttggct ggatcgatcg cactagctaa aatggtacca tcggcagcta ctgcctgcag
     7201 ggttactcgg ctgctataat tagcatctag cacctgatca tcaggtaatt tagcgacaac
     7261 atgatctatc aaggcaatag tagactcatc acttgtgacc tcaaccttgt caatacctgt
     7321 ttcaattttg ctaatctcat agcccttagc cagctgctta ctatcgacgc tgccacgcac
     7381 cggaaaggtc tttgttttct tatttccaat cgttaccgaa atcttatcag gagaaacagt
     7441 tgctgtcaca ccagtaggta gattgataac ctttagggtc accgttgcag tacctggctt
     7501 actctttgtt agatcagcta cgatcttaaa gcttctagtg tcactgttta cctctgaatc
     7561 cagctttatg cggttggtag aggtcagata aacctctgca ccgtaagaat agccgctgat
     7621 gaagtactga tcactatcat acttgatatc aataggaacg tcctttaagc tatgggtgta
     7681 ggtttcaata gggctataaa tttgagaatt agaatgatta tgactgctag aagcagcggt
     7741 caaaaaaaga ataatcgcaa aaaagattga cactaagccc agcccaagac gactatttaa
     7801 aaacctcttc atttagcttt gcctcctaag atttttttat accaaggtaa tgtcgcaccg
     7861 ggctcattca tcaaatgagt cttgagaacc gcctcaagct cttctgttga aaggtcgtgt
     7921 aaaaattgac ccttacgagc gatagagaca gctcctgtct cctcagaaac aattatcgtt
     7981 acagcatcag aattttctga aagtccaatt gctgctctgt gacgtgttcc aaattctttg
     8041 gaaatcgaca ttgattcaga caaggggaga taagcacagg ctgcagcaat tttattgtta
     8101 gccacaatga ccgcaccatc atgcagcggt gtgtttggga taaagatatt gatcaatagc
     8161 tgactagaaa tatcagcatt taggggaatt cctgttgcga tatattcctg caaggtctgc
     8221 gtttgctcaa tagcaatcag agcaccaatc ttccgcggtc ccatataagc aactgatttt
     8281 aagagcgcat caaccagcat ctcctcatca ctcaagcttt gcttttgcaa aaatacctgt
     8341 gttgatcggc caaatttttc aagccccgct cgaatttccg gagcaaaaat caccacacct
     8401 gcaatcactc cataggtgat gacctgattc atcagatagg ttatagtcgt aaaccctatc
     8461 cactcggcaa tcacacgaat gatgataaag aatataaccc cttgtaccaa ggacatgatc
     8521 ttagttcctg ccaaggattt aataaaacgg taaatcaaat aggctactat taaaatatcc
     8581 agcaaatgaa ccaccaacat caaggggtca tcaatcaggc ttagtaaaaa ttttgtgtca
     8641 atacttgata aattactcat acaattctca tttctatgtc agatagatac ctctaacatt
     8701 atatcacgtt tcaagatgtt ttccctatct aaaatttaag aacttatgtt aaaatattaa
     8761 catgaaacta aagacactac tcgctatagc agccggaagg actgcgcagc tcattttaaa
     8821 taaaatcgga agaggctcaa cctaccccgg acgattggcc ttgatgtggg ataaggatat
     8881 tttagacaca cttgccaagg actatgagat tgttgttgtg acagggacaa atgggaaaac
     8941 cttaaccaca gctctaactg ttggtatcct aaaagaagcc tttggtgagg ttttgactaa
     9001 tccaagtggc gccaacatga tgacagggat tacctctgcc tttttatctg ctaaaagaaa
     9061 aaaaacaggc aagcctattg ccgtcttaga gattgatgag gcaagccttg caagggtaac
     9121 aacatacatt aagccaagtc tttttgttta cactaatatc tttcgagacc agatggatcg
     9181 ctacggtgag atttacacca cctatcagat gattgttgat ggtgctagtc aagcgccgaa
     9241 ggcaaccatt ctagctaacg gtgatagccc tatctttgcc tcaaaggacc tggttaatcc
     9301 tgttaaatat tatggctttg acacacctaa gcatgagcca cgcctagctc actacaacac
     9361 tgaaggcatt ttgtgcccaa aatgtgaaca gattctccgt tatcgtctca acacctatgc
     9421 taatctagga gactatacct gcttaaattg tgatttccaa aggcctaagt tggattacaa
     9481 gctaacgcaa ttaaccagca ttacccatca tagctcagcc tttgtgattg acgatcagac
     9541 ttatcgcata aatgttggag gactctataa catctataat gccctcgcag ctgttgctgt
     9601 tgctgagttt tttggcattt ctgctgatca gattaaggct ggcttcaata aaagcaaggc
     9661 tgtttttggt cgtcaggaaa ccttctccat caacggtaaa gcctgtacgc tggttctcat
     9721 taaaaaccct gtgggtgcta gtcaggcact agaaatgctg cgcctagccg attatccctt
     9781 tagcctatct gtgcttttaa atgctgatta tgctgacggt attgacacaa gctggatttg
     9841 ggatgctgat tttgaattga ttaatcaaat ggacattact gagatcaacg ccggtggggt
     9901 tcggcattct gaaattgcaa gacgcttacg agtgacaggc tttgatgagg ctaaaatcac
     9961 atcattcgat aagcttgaag gtatcatgca agccattgaa aaccaagagg ctgagcatgc
    10021 ctatatccta gcgacctata ctgctatgct agcatttcgt gagctgcttg ccagccgcca
    10081 cattgtcgaa aaggagatga tctaatgacc tatacctcgc tacaatctcc ggaaaatcgc
    10141 gattatcaat acgaccttca tattgctcac ctttatggta atttgatgaa tacctatggc
    10201 gataacggca atgtcttgat gttgaagtat gtcgctgaaa agctaggcgc taaggttaga
    10261 gttgatattg tatccattgg ggataccttt gaccaagatg attatgacat tgttttcttt
    10321 ggtggtggtc aagattatga gcaagccatt gttgctagag atttgccatc aaaaaaagag
    10381 gccttagcag cctatattca ccaaaataag gtactccttg ccatttgtgg tggctttcag
    10441 ctgctgggac agtactatat tcaagccaat ggccttaaaa tcaatggcat tggggttatg
    10501 ggacattata ccttaaacca agataataac cgctttatcg gaggcattaa aattcacaat
    10561 gatgactttg acgaaaccta ctatggcttt gaaaatcatc aaggacggac ctttttatct
    10621 gacgatgaaa agcctcttgg acgtgtcatt tatggaaatg gtaataataa agaggaccaa
    10681 actgagggcg tccactataa aaacgtttac ggcagctact ttcatggacc aatcctttcg
    10741 cgtaatgtca gcctggccta tcgcctagtc acaactgctc tcaaagaaaa atatggctcg
    10801 actgtttcct tagcggccta tgataagatc ttacagcatg agacctcaga ggaatacgct
    10861 gatgttaaaa gcaaggctag ctttgacagt taagtccttc tcatagcctg attaaaccac
    10921 aacagacatg caaaacagtt attcccgaat gaaaatatag atttaaatag acaccctcaa
    10981 tgtttttcct atcataaaat ccataaaaga taagacatat tcttgcaata actgaacatt
    11041 gaaagacaga aagctttctg tccttactaa acatctttca tgcgtctgtc gtgctgatca
    11101 agcgagataa ccccaaaaaa gtgctagcac agtaacaaaa tggctatgac catatgtctg
    11161 tgcagctcta ctgtcactgc atagacaggc tagaggggac gccctacttg gttcagcgat
    11221 ctaggggtag gtctagcttg tttgtgctga gtctgtttcg gtagcaaaga ttgaatcctg
    11281 ctataagata ctctcaaaaa gattaaccca aaagccttgc aacacattta acgtttttag
    11341 ggataagtac cgatatgcag acacatagca ggagatctat gtgtctggta ccaaaggaca
    11401 caaaaaacta aagtaacaca ctaaaagcca catgataccc atttgatagg gggcgtcatg
    11461 tggctttttt ctatctcact gttcattaca aaaagccaaa ccagcttctt tttgcattag
    11521 gcaacaatgg cctttgccac ctcttctact gtcatacgtg agaaatattg tgttgtatca
    11581 atggtttgaa gacgctcaag cacatcagca tactcgtatt tgcaaccaat gagtaggctt
    11641 tcaatatcct gcacgtcctt aataccaaag aaatcaccgt agatcttaag attcttaata
    11701 acagaatttt caacattagc aaaggttgag attttaccgg cagggtagcg aacattacgt
    11761 tcaatcgtgt attcaggtgc ctttccatag gtccaatccc agctcccaaa ttgctcctca
    11821 gccgattgtt gaatcttagc cagctcgtcc tctgacaaga cgtattctgt catgtctgga
    11881 taggtctcct tcattttaac caaaatcttg tctgaaaatg cttctacgct gattttttct
    11941 ggcagctcat ttaaaatatt ggtcacgcgg gctcgtacag atttgactcc tttggactca
    12001 atcttatcct tactgacctt gagcgcatca ccaagaacag tcatatccac atcaaacaag
    12061 agacagccat gatgcatcat acgtccctta taataggctt gagcattgcc acagattttc
    12121 ttgccatcaa tttcaatgtc attgcgacct gtaaaattag ccttaactcc taaatcagcc
    12181 aaggtctcaa taactggctg tgagaaggtt ttaaaatcaa aggctccttc tgttgtttta
    12241 ttggaaataa tcgtgtagtt aaggttattg agatcatggt aaactgcacc accgccagac
    12301 aagcgacgaa ccacatgaat accatgctgt tcgatgtact ccttgttgat ttcctgaatg
    12361 gtattttgat gcttaccaat aataatagcc ggctcattga tccagaggat aaacaattca
    12421 tcctcatcaa ccaattctct aaaggcataa gcctctagag caatgttaaa ggcagggttg
    12481 tggctcttat taacaatgta tttcatttct atctcctata gcgataatcg ttatcatatt
    12541 ctattcttta ttctaatgga aactcttaca aaagacaagc taaaagaggc tagcaaaagc
    12601 aagggaacta gtaaatgctt cctcaatcaa gaaccatctg caagctagca gtaaagcttg
    12661 atctaactta aagagccttc cttgtatcaa cgaaagagct gagaaatctt tttcccagcc
    12721 cttttttatc gcagctatat agctagctta ttttttacgt tttggtgggt tatgaatggc
    12781 ttcgccaagc acatctgcaa aggcttcgta catcacctct gagaaggttg ggtgtccatg
    12841 aattgacaat agcaattcat caactgttag ctcagcctcc atgattgtgg ctgcttcatt
    12901 gatcatttca gcggctgctg gaccaatgat gtgaacacca agtatttcat ggtatttagc
    12961 atctgcaata acctttacaa agccatgagc ctcgtttgac gcaatagcac gaccatttcc
    13021 tgtaaagcta tttttaccaa taagaacatc gccatattgc tcacgagcct gctcttcagt
    13081 taaaccaacc atagcgacct cagggtgagt atagaccgcc gctggagtgt attttaggtt
    13141 agccttacgt gttgtgctgc catgcatggc attctcagca gccacctcac ccatacggta
    13201 agcagcgtgg gcaagcattt tagtgccgtt aacatcaccc ggtgcataaa tgcctgggat
    13261 tgacgtttct tggtagtcat taaccttaat gcggttacgg tccatttcaa ggttgaggtt
    13321 ttcaagacca ttcatctgtg gcacacgtcc aatagatagc aaggcctttt cagcaacaac
    13381 ctcttcgcca ttattaagct tcaaggtcaa ctggttgttg gcttcaacaa tctcagagac
    13441 accaactgag gtctttattg tcatgccttt cttagaaagg attttttgaa gctccagtga
    13501 aacctccttg tccatggcag gaataatgcg gtcagccatt tcaataactg taacctctac
    13561 accgtaagag gcccaaacaa gaccaagctc aataccaaca acaccaccgc ccataacagc
    13621 aagtgatttc ggcatttcac gcaaatcaag aatatcatca gatgtcaaga caagcttaga
    13681 atcaatccct ggaatattga tgcgtgagac cttagagcct gtcgcaagaa taatattgcg
    13741 ccctttaatg gtttgcacac caatggtaac cgttttatca ggatttacct gaccaaggcc
    13801 attaaagatg gttaccttgt tggctttaag aagcccttga accccacctg ttagcgtctt
    13861 aacaaccgta tttttaaagt caactgtctt atccatgtca atagtatagt tggttgaagc
    13921 aaggttaatc ccgcgtcctg ctgcaatctt gatgccatca aggatttcag catttttgag
    13981 gtaggttttt gttgggatac agccaacgtt taagcaggta ccgccaaatt cagatttttc
    14041 aacgatagca atcttgccgc ccagctgagc accacgaata gcagcgtagt aacccgcagg
    14101 accgccaccg acaacaatga tgtcatattc atcagcagca agctctgcct ttggtgctga
    14161 tggcgctgat ccttgatccg gtgcctttgg cacctcaaga ccagccgcct gtaaatcctc
    14221 ggttgtacgc gcaacattga catcagccgc tgctgggctt gatacatcga tagcttcacc
    14281 cgcagctcca atgtagccga taacttcggt tacagggact gtctcacctg cctggcgaat
    14341 gatttttaaa agcacacctg agtcttctgc ttctaattcc atattggtct tgtctgacat
    14401 gatttccaga agaatgtcac cctcgctgac agtgtcaccc tcctgctttt tccactcgat
    14461 gatctcgcct tcttgcatgt caacaccgag ctttggcata ataatttcaa cagccataat
    14521 gatattgtaa ggaacgttca aatgcaatca gatgccttaa caatcagcac tggctaacat
    14581 aagcctgcta aaagccctgc atttagctca tagctagtga ctacgagctc gttccagatc
    14641 ctttctatag ttttaaagaa ttatcttttc gttactttgt ttctgaaata tgctctcttt
    14701 gcatcgcagg ccataaggcc tgtcatcaga ttagcagttc aaatggattt tccatcaatt
    14761 ttttgagatc aaccatgaat ttagcaccat tcatgccgtc caccagacgg tggtcaattg
    14821 tcagacacat tgccatgatt ggacgtgcaa caatctcacc atcgaccact gttggggttg
    14881 gaatggttgc cccaatacct agaatagctg aattaggctg attgataatt ggattgaagg
    14941 ttttggtgcc aaacataccc agatttgtga tggagaaggt tgagcctgac atttcggtag
    15001 cctttagctt gcctccttga gcctttttga taacgtcctt agaagcaagg acaaactctg
    15061 agagactcat cttatctgca ccatgaacaa ctggcacaac tagcccatca tcaagtccta
    15121 cagcaatacc aaggttgaca aagcgatgaa gctcaatatc attagcatca ttaatcaatg
    15181 acgcattcat gtattcgtgc tctggcttca tcaaggtctt aacaacggct aaaccaatca
    15241 agtcagtaaa gctaaccttt agccctgttt tagccatgat tgggtcaatc agcttcttgc
    15301 gcaaggcaat catttcggtc atgtcaatgt cataattaag cgtaaaggtt ggtgctgtaa
    15361 ggtaggaatg tgtcataccc tttgaaatag ccttacgcat agcagacatc ttcttaattt
    15421 caacaccctc tggaagctcc ttagcaggct tttcttcagc aatagatgct ttttccacag
    15481 caggtgctgc tgcgccaagc acagccaaaa tgtcctcctt ggtaatcttg ccaccaatac
    15541 ctgttccgac caccgctgca aggtcaactc ccttgtcggc agctatctta cgagcaagtg
    15601 gcgttgcctt aggctgagct cctttgaagc cttcaacgtc ttctttgtgg atacggccct
    15661 ttggtcctgt tcctggcact tggttaagct caattcccat ttctgaagct gctttacgag
    15721 ctgctggcgt tgcgcgtacc ttttctccga aggctggagc attggcaact gatgctacct
    15781 gaggcgctgt tgaggctgct tctttcggta cagttgttgt attagcttct gctgatgttg
    15841 gtactggaat ttcagttgtt ttctcacttg aagcagtact attatcaaca gattcacctg
    15901 cagcaccaat atagccgata acctcagtga cagggactgt ttcacctgcc tggcgagtga
    15961 tttttagaag cacacctgaa tcctctgctt caagctccat atttgtcttg tctgacatga
    16021 tttcaagaag aatgtcaccc tcgctaacag tgtcaccctc ctgctttttc cactcgatga
    16081 tctcgccttc ttgcatgtca acaccgagct ttggcataat aatttcgaca gccatatatt
    16141 tcctttcatt taatcccgca gcccatgatc ttaagaccag atacagctgc tgaaaaaagg
    16201 gatactgttt tatcagcctg atgaagaaag cctctaagct aagacttcct ttgccatgct
    16261 aatttccctt gttgaccatt tttacaatag cagccttgat tttagcaaca tctggtaaga
    16321 tagcttgctc aagaacacgt gcataaggta ctggtacgtc ctcactagca agacgcacaa
    16381 ttgggtgatc aaggtaatca aaggcttcac tttcagtgac cattgctgca atctcaccga
    16441 taaagccacc agtcttatag gcatcattaa caagcataag cttccctgtc ttcttaacag
    16501 aattaataat taattcctta tctagtggga taagggtacg tggatcaaca acctccacat
    16561 taataccatc agctgcaagc tcttcggctg cctgaaggac acgctctagc atacgcccat
    16621 aggaaacaat ggttacatca gtcccttcac gcttgatatc ccccttgcca agtgggatat
    16681 aaaaatctgg atcctgattg acctcttctt ttttaccgta caaggcctta ggctccatga
    16741 aaataacaat attgttatca cgaatagctg actttaaaag tccctttgct tcgttagcag
    16801 ttccaggtgc aaccaccttg atcccaggaa tatgcgtcaa ccaagcctca agagattgcg
    16861 aatgctgagc tgcagatcca attcctgagc cagaagcaac acgaaaagtt gctggcgtga
    16921 tcaagccacc accaaacatg tagttgtttt ttgccccatt attaacaatt gcatcaagtg
    16981 caatggtaat aaagtccata aaagtaaggt caacaatcgg acgaagccct gtaattgctg
    17041 aaccaatcgc tgcacctgca atagcagcct ctgaaatcgg cgtatccttg acacgtttgg
    17101 caccaaattc ctcaatcatg ccaacagaag taccaaagtc tcctccgtaa acacctacgt
    17161 cctcacccat aaggtaaatc gtgtcgtctt tgcgcatctc ctctgtcatg gcaagattga
    17221 tagcctcacg caaagccatt aattttgttt ctgtcattat tatctcctaa tgtttacaaa
    17281 atagaattgt caatgttact gtgaatagat ttttgctcga tgtgctagca gatcagctag
    17341 tctacccaaa cgtcctcaaa ggctacagaa atgtctggat ctggactatt ttgtgcaaac
    17401 tcataagcgt catcaatttc ttgcttgacc tgtgcttgaa gcgcatctaa ttcttcatct
    17461 gtagcaatgc cttcacctgt taggtaagcg cgatacttaa gcattgggtc cttttccttc
    17521 cactcatcaa cctcttcttt ggtgcggtat ttgccggcat cagcagttga atgaccaaac
    17581 caacggtaag actcaacctc aacaacagca ggaccattgc caccgcgaac atgctcaaca
    17641 gccttactca tggtttcata aactgccatc acatcgttgc cgtcctcaca ataaaagcct
    17701 ggaataccat aagcctcagc acgcgtgtag aggtgaggtg tatttgtggc attgttaatg
    17761 ctcatggaaa tcccatagcg gttgttaatg ataaagaaaa tcacaggaag cttccaagtt
    17821 gctgccatat tgacagactc atggaaggag ccctcatttg ttgcgccatc tccagaaaag
    17881 gccacaacga tattgttggt ccccttgtat tgctgtgtca aggcagcacc taccgcaagg
    17941 gcatagccac ctccaacgat accatttgtt ccatagtttc ctttttcaaa atcagccaag
    18001 tgcattgagc cgccgcgtcc ctttgacaca cctgttacct taccggctag ctcagccatc
    18061 attttattga ggtccatatc tttagcaata gattgcccat gcccgcggtg gtttgaaaaa
    18121 ataatatcat cataggtcaa atgtgccaca gcgccaacgt ttgctgcctc ctcaccaact
    18181 gagaagtgtg tcatgccctg cacaaatcca cgacggacaa gcttattaat acgtgaatca
    18241 aattcacgaa tacgctccat tttaaggaac atatctaaat gttgttcttt agaaactgtt
    18301 accatttcgg cctccatatt atcatattac ttcctaatca taaaactttt cttcacaatt
    18361 tgcaaggatt ttaatcgctt tctttgtgac tataaaagct tttttaagac gttttagttt
    18421 gtggtttcac aagctagatt gttatagcat ctgttacatt tatatataac agattgaaaa
    18481 atgagtcagt gtttattcag ggaggtcaag cacctattga ctttgatagt cagaaatatc
    18541 atcactcttt aagaggaaaa taggctctaa atgacctgtt tcttctagca caatcatgat
    18601 cacctaccaa acgaacgctt tgcttgcctc gctccgatag aggcgaaatg aactaaaaat
    18661 cgcataacta aaaatgcctg attttacctg aaaatcagac atttaaaagc tttaagacat
    18721 tagactcagg ctctaattat aatcctctaa gaaaagcctg ctaccttgca ctacccaaga
    18781 atagcaaggc aatttcatta tctcaccagg ctactccagc tgtcctgcaa tgtcctccca
    18841 ctccagcagc aaggtctcct gtttctgatt aagctgatcc aactcttttt gccagtctat
    18901 cagttgagtc gtatcatttg atactagcat ttgagcttct atagccttag cctgtgcttc
    18961 tagcccttct aaggtctgct caatctcctc aaagcgcctt gttaagcgac ggtattcctt
    19021 ttggctggcc ttttgaagct gataatcagt tacagcagct tctgctacat cagtctctac
    19081 tacgtgatct gcagcagcta gacgggctaa ttcctcccgc tctgcctttt tttctacata
    19141 atagtcgtag tcccccagat agagtgttga gcctgcttca gttatttcta aaaccttagt
    19201 ggccactcgg ttgataaaat acctgtcatg actaacaaac aacaaggtcc catcaaagtc
    19261 aatcaaggca ttttctagaa cctctttgct atcaatatcc aggtggttgg ttggctcatc
    19321 tagaatcaga aaattgtcct ttttcataga taattttgtt aagagcagcc gagccttttc
    19381 gcccccagat agcatggcca cagacttttt gacgtcctca ccagaaaaga gaaaggcacc
    19441 taagcggctg cggatctcaa gctcagctgt cgttgggaaa tcacgccaaa gctcctccaa
    19501 tacagaatta ctaccagtca gatgagattg cgtttggtca taatagcctg tttcaacatt
    19561 agtcccataa tggcatgtcc ctttaatcaa aggaatctct ccaataatgg atttgagtag
    19621 ggttgacttg ccaataccat ttggcccaac aatagcgatt gcatctaacc tacggacatc
    19681 tagatgaatt ggctcagcta aaatatggtc attgtagcca atagcggcgt ctgtcacctg
    19741 caaaacaaca tttcctgagg gcttatcaat ctgaaaagtc atactagctg atttgcgaga
    19801 gctacttggc ttgtctaagc gttctagctt ttctagctgc ttgcgtcttg cctgagcacg
    19861 cttggtcgtt gacgctcgaa caatgttttt ttggacaaaa tcctctagct tagcaatctc
    19921 tttttgctgc ttgtcataat gcttctcttc tgctgcaagc ttttcagcct ttaaatcaat
    19981 aaagcgtgag taattaccaa catagcggtc taagctattt ttagtcagat caagtgtgat
    20041 ggttgcgacc ttatccaaga aatagcggtc atgactgaca atgatcaagg ctccctgata
    20101 atttaccaga taatgctcca gccaggcaat ggtttcaata tctaaatggt tggtcggctc
    20161 atcaagcacc aatagctctg gcttttctag tagcattttt gccagggcca aacgggtatt
    20221 ttgcccacca gaaagctctg agattttcat ttcccacatg ctttcgtcaa acttaaagcc
    20281 atttaaaata gctcgaatat ctgactcata ggtgaagcca tttcgcaagc gaaagctttc
    20341 tgacagccgg tcatagtctg acatgagctg gtccagagct tgccctgatc gactggccat
    20401 atcagcctcc atttgcctta gtcgctgctc atcaaccctc aattcagcaa atacctttag
    20461 catttcctga taaatggtct tgtcagactc aaatcggcta ttttgtgcca aataagatag
    20521 ggttaagtcc ctttttcgac taacctcacc gctagttggc tcttcttctc caactaaaat
    20581 cttaagaagg gttgatttgc cagcaccatt tggcccaacc aaggcaatgc gatcacgttc
    20641 accaacctgc agcgataggt tttgaaaaag cacctctcct gaaaaagagc gctcaatgtt
    20701 atttccttgt aatataatca tacccttatt gtagcaaaaa aatgcccttt tggggggcac
    20761 ttttagttat ttttacaggt aagataagac tcatcaacaa gctaaagaca taagccttag
    20821 gctaacatcg cttatcaccc ttagtggtat ttatctgatg agacaaactg ctgcttgaaa
    20881 aaccagtggg ttgacctgtt agcgtatcca acaatcgcac cacctgctca gttatgcttg
    20941 aaatgctatt agccagtgag gaatcactat ggttcgaata ataaatcaaa ccaaaaataa
    21001 gcaataccaa tactattagg gtctgcaaac agcctctgac aagctgccag acaagcttca
    21061 gcagaagctt tgggaggcat aagaggatag tcagtagttt tttcatcgta ataagcctaa
    21121 attctttcgt ttaggatagc ctttcttcct tgtggtaagc aatcggcagc caatctaata
    21181 gggcctctag ctgctgattc caataatacc attcgtgcct gccatgatcc ttacgataat
    21241 caatagtcaa gccaagcctt ctcaactcag caactgcctt ttcattggct tcaaacaaaa
    21301 agtcctcata gccacaccaa gcgtatagct gggtttgacc atcactttct gctgctatac
    21361 ttgtcaaata atgctttttg atatcaggag cattcaaatc tccaaaaaca ccctgccaat
    21421 aaggcagctc acctatacct tgctgtaata gcatttccgg cgaaaaatgc aaggccccag
    21481 aaaaggaagc agcataggaa aagcgattgc tttttaaggc ccatttaaag gcaccatagc
    21541 ctcccattga cagcccagca acaaaggttt tttcacgctt agtggtcata ttaggaaaga
    21601 aagaagctaa tagccgagga agttcctctg caatagcttg gtaataattc ataccgtagg
    21661 tggtatcggt ataccagcct aaatcagtcg atggcatcac cacgattaaa ttggtatggc
    21721 gaagcagcct ttcaatatta gtccgctttt gccaggaatt ttcatttcct cccataccat
    21781 gtaacagata aagaactgga atatcttggt agccttgctc ttctgggcta agctcagact
    21841 gatcagggta gatcaccttg acatgtcttt ccatagccaa gatctctgaa tgatactcaa
    21901 tgctaatgct tgccatcagc tcacctcctt tttaatatca ccaaagcata aggaaagccc
    21961 actcttaaga cctaaaagcc agatcctatt tgaccagctt ttaggcaggg ctgtatctgt
    22021 attaacggac ctccataaca accggaagaa tagctggccg acgcttggtc tgctcaaata
    22081 aaaaccttga gagctcctct ctaacagagc ctttcaattc actccaatca aaatgatccc
    22141 cttgcagata attgccaact gttgtgttga ccaattcagc actttctcgt aaaatatctc
    22201 tgctcttttt cacatagaca aatccgcgag tgttgacctt agccttagag ataatacgtt
    22261 tttccttttt agatactgtg atcgcaacaa taaaaatacc gtcctctgat aagaccttac
    22321 ggtctctcaa aacaatattg ccaacatcac caatggcatt tccatcaatc atcacatcac
    22381 tagcaggaac cgcaccctcg tgtaagaagc catcctcatc aagcaccatg atgtcaccac
    22441 gcttcataat atgaatattt tcaggtagta taccagcctc ctcagctaaa tgagcatgag
    22501 cagctagatc gcggtattca ccttgaatcg ggaacaggta ttttggtttg acgagattaa
    22561 tcatcagctg caggtcacgc gcattggcat gtccagaaac acgtaaatgc tgcgtgatga
    22621 gcttaacaga gccacctgct ttatagataa ggttttcaac acgagcaacc attgcttcct
    22681 tggcagcgct tggcgttgtg acaatgtaaa ccagatctcc gtccttgatt tgcacgtggc
    22741 gatgacgccc tattgccatt ttctgtaggc tattaatcgg ctcacccata cgtccagcct
    22801 ccagaacaat caattcgtga tcctcaaact tagacatatc ctttggcttg attaatagct
    22861 tttcatcagc aatcactagc tttttaagac gaagtgctgt tctgacaata ttttcagcgt
    22921 cagtacctgt cagtaccact cgcctgctat aggctgctgc agaatcaaag acctgctgga
    22981 tacgaacaag atttgaagcg acagctgcaa taataatccg cccgtcggca tgagcaatca
    23041 ccttatccat ctcctcgcca acctcagctt cgctggcagt ctgctcattg cttgtggcat
    23101 tggccgagtc agctaatagg gctaacaccc cttcttttcc aatgtctgcc aagcgagcta
    23161 ggtctgtctg atagccctca cgcgaagcct ggtcaaactt gaaatcacct gtatagacaa
    23221 tattcccctt atcggttcca ataaccacgc ctaaactttc aggaatagaa tgtgttgtct
    23281 taaagaagga aaccaagcca tctttaaatt caatttctgt gtcactgtcg accacatgga
    23341 aattcttaaa tctcttggtg ctattattgg ccttgacaaa caattttgct agctcgatgg
    23401 tcaattctga accaaatact ggcactggaa cctccgccaa caggtaaggc aaagctccga
    23461 tagcatcagc atgcccatga cttaaaaaga ctccctgaac cttgtccttg ttttcaatta
    23521 cataatcaag acttggaatt accaaatcta cacctagctg ttctgtttca gggtatttca
    23581 agccagcatc caaaatgaac atggaatcgt taatctctac tagatagaag tttttcccgt
    23641 actcacgtac gcctcctaat gcaataatgt ttatatcagt catgatactc ctttttttat
    23701 attagttatt acaaacggtc cttactgggt aagtcgaatt actgtcttgc agctaagctg
    23761 cactctttta cagtatatca tattttaggg cttattacct caaattgcct tgagactttc
    23821 tcaatctttt caatagatta tcaaaaaagc caagggaagg ctttcattcc aatggctttt
    23881 agagtattta ttttagtcaa aaagctggta ataatcagca atggtcattt gagattttct
    23941 cttctgatca aggtcttgaa tgattttacc atttttcatc acaatcaggc gattaccata
    24001 gttaagagcg tcctccatgt gatgcgttat cattaaggct gtcaagcgat ccttagctac
    24061 aaaatcatca gtcaaggcca ttaaggcttg gctggtctta gggtctagcg ctgcagtatg
    24121 ctcatctaat agtaaaagct ctggtctttt tagggttgcc atgagtaagc taagggcctg
    24181 tctttgaccg cctgataaga gaccagtcgg agtctccaga tgattttcca agccatttcc
    24241 aactcgcttg accaagtcag caaagtctgc catataatgg ctaatcctgc gtgatgacaa
    24301 gcctcgcctt tcccctcttt gccttgcaat caaaaggttt tcagctactg tcattcgagg
    24361 tgctgttccc attttaggat cctgaaaaac acgtgatagg tagctagctc ttttttctgc
    24421 tggcaggtgc gtcacatcat gccctaaaag cttaatttga cccttgctta acaatagcgt
    24481 cccagcaatc acattaaaaa gggttgattt accagcgcca ttcccaccaa gaatcgttaa
    24541 aaaatcatgc tcataaatgg tcaaggaaac atcatctaaa atagccttag tctcatcaaa
    24601 gccattattg acttcgacag tagcgtgaat taattcaata atttttctca tcgtgataag
    24661 ctagcctcct taataattgc tttttttagc acaggcacca tcaggcaaag tgctaatata
    24721 atggcactaa atagcttaag ataatttgta ttaaagccaa gagcaataac tactgagatt
    24781 aaaaattgat acaggataga accaaccaca atggctatca agcgctcaag cagggttagg
    24841 cctgtagaat ataaaacctc accaacaata atactcgcaa ggccaattac aatcacacca
    24901 atcccctttg aaacatcagc atagccatct tgctgactaa ccaaggcacc agataaggct
    24961 atcaaggcat tagagatcgc taagcccata agctccatac gatcagtatg aatcccaaag
    25021 ctcttagcca tatcccgatt atctcctgtg gcaatataag cctgaccaat attggtgtaa
    25081 agaaaataca ttaacaaaaa aatcaccaat gtagctacaa ccaaaccagc taccaacaca
    25141 ttggtgtcag ctgcaaaggg aaggtagtcc tgaatgcgct tgatatcatg caagcccaaa
    25201 ttggccctgc ccataaccat aagcataatg gaatggcagg aggtcatgac tagtatgccg
    25261 gcaagaagtg ttggtatctt tccttttgtg tataacaggc ctgtggcgaa gcctgccaag
    25321 gcacccgcca gcatagcagc cagagtagcc aggataggat ttaaaccgag attgagcaga
    25381 gttactgcta cagcacctcc taaaggaaag gacccttctg ttgtcatatc tgggaaattc
    25441 aatattctaa aggtcaggta aatccccaag ccaagaattc cccataacaa gccttgtgat
    25501 acagatgaaa taatcatatg aactcctttt ctattgctta cctgtaaggt cagaacgctt
    25561 cagcaggtct tttgagatca taagacctaa atcccttgct gcctttagat ttaaaaatgg
    25621 cttaccgtca tcaactacct cgacaggaac ctctgatacc tcttttccag ccataagctg
    25681 cagcacctgc ctagctgtct caacccctaa ttggtattga ctttgtgaaa tagaagcaag
    25741 actcccttgc tcaaccattg tatcaacact tgagtagacc ggaagctgtg ctgcatttga
    25801 ggcaacaatc accgctgaaa aagcactggc aatagtatta tcctgtggga taaaaacagc
    25861 atctaccttc tcagtcatca cagacatggt cgtggtaacc tcatttgttg aggggacagc
    25921 gtaagctaga acctccaagc cttgcttttc tgcaagagct gtaaagtcct tgacctgtga
    25981 tattgaattg tcctcactgc ttgcataaag gacaccgacc cttttgacct gaggggtcat
    26041 ctccttgatc agatcaaccg tctgtcgaac aggaacctta tttgataagc cagtaacatt
    26101 tgcctcaggc ctgtctaagt gcttgactaa tttagcacca actggatcag aaatagctga
    26161 catcacaacc gggatagtct tggttgctgc tgctaatcct tgagctgcag gcgttgcgat
    26221 gccaacaaca atatcgtttg ttttgaccag ctgcttgctc atggtctgaa tcttactttg
    26281 atctccttct gcattcataa gggtaatgct gaccttttgc tctggctgat gatgcttctt
    26341 tagctcgtct ttaatgccct gtgcaatctg gtcaagcgcc tcatgagtaa ccagctgcaa
    26401 tataccaacc ttaaccacac gcttgctggc taactgtggc tgttttttgc cctcttttag
    26461 cactagcgaa gcagcaacca ttaaaaagag tgcaatgact gttacgataa gacctttatg
    26521 tttcatgttc tacctcttaa tttccattct tactccgttg ctaacattta gagtactcac
    26581 aaaaagaaaa aacgcttagt aatcagctac taggcgcttt ttttgaaatc caatgtcagc
    26641 gcatagatac ctttttagaa gtactctaaa agtcgtatct atgctaaccc ataaacacaa
    26701 ctttatctat gccagctttg ccaatttatc atatgctgtg tttgcttcat cttggatttc
    26761 ctttcttgtt tttttacatt ataacctaaa agctcaaaaa tacaagagca tttgaacata
    26821 tttttccatt attttttgtg gtataatgaa agaattagaa ctcaggaggg agaaaccatg
    26881 tcatttgacg gctttttctt acatcattta actcaagagc tcaaccatag tattgttaat
    26941 gggcgcattc aaaaagtcaa tcaacccttt gataatgagt tggttctgac tatccgtaac
    27001 catcgccaaa cttacaagct cttgctctca gctcatccgg tttttggacg cattcaactg
    27061 acccaaacag actttcaaaa tcctcaattt cccaatacct ttaccatgat catgcgcaaa
    27121 taccttcaag gagctatcat tgaaggcttt gagcagattg ataatgaccg catcatcgaa
    27181 atgaccgtct ctaacaaaaa tgagattggc gatgccataa agacgacatt gatcatcgaa
    27241 attatgggca agcacagcaa tattattctg gttgaccgtc atgaaaacaa aattatcgag
    27301 tctatcaagc acgtcggctt ttcccaaaat tcctaccgga ctattttacc aggatcagcc
    27361 tatatcgagc ctccgaaaac aactgctgtc aatcctttta cgatctcaga tatcgcttta
    27421 tttgaagtcc tgcaaacaca ggagttatct gctaaaaatc ttcaaaagca tttccaaggg
    27481 cttggccgag ataccgcaca agagctatcc agtctcctga caactgataa gctaaaacgg
    27541 tttagagact tttttcaaag acctagtcag ccaagtctaa ctcagacctc ctttgctcca
    27601 gttgccttct caaacacact gaagaccttc cagaatctat ctcagctgct agattattat
    27661 tatcatgaca aggctgagag agatcgtatc aaccagcagg ccagtgacct gatccaccgc
    27721 gttcaaaacg aattggaaaa aaatcgcagc aaactgatta agcaagaggc tgagctgcta
    27781 gccactgaaa atgcggagga ctttcgccaa aagggtgagc tcttaacaac ctatctgagc
    27841 ctggtgccaa atgaccagga ttcagttgag cttgataact actataccgg ccaaaaaata
    27901 accattgcac ttgataaggc gttgactccc aatcaaaatg cccaacgcta ttttaaaaaa
    27961 tatcaaaaat taaaagaagc tgtcaagcac ctctcaggtc tcatcgctga cacgcaacaa
    28021 accatcgctt attttgaaag cgttgattac aatctatctc aggcaacgat tgatgaaatt
    28081 gaggacattc gagaagagct tattcaggct ggctttgtga aaagccgtaa gcataacaag
    28141 caccacaaac gtaaaaagcc agagcaatac ctggcttcag atggcaaaac aattattatg
    28201 gtcggacgta acaatctgca aaatgaggaa ttaaccttta aaatggccaa aaaaggcgag
    28261 ctctggtttc atgctaagga tattcccggc agccatgtga tcattaagga caatctaagc
    28321 ccaagcgacg aggtcaaaac tgatgctgct gaattggcgg cctattattc taaagcaaga
    28381 ctttccaatc tcgttcaggt ggacatgatt gaagccaaaa agctgcacaa gccaagtggt
    28441 gcaaagcctg gctttgtcac ctatacagga caaaagacac taagagtgac acctatagaa
    28501 agcaagattc aagccatgaa gtgctcccct tcagcctctt cctcatagga ctacagcaat
    28561 aaagataaaa aaagctacag cctcacactt ggagataggt ccagtcttaa agctgcggct
    28621 tttttatcat tacttgttaa tcatctctca aatcatctaa gaagccttgc atatgaatat
    28681 catctggaac ctgctgcaaa tacctttttg cctgcttaac tgcttgatca gtatagccga
    28741 attcccttaa taaataagca taatcctgta aaaagtcagg attttctttt aggtctcctt
    28801 cgatatcttt atagatagtg agggcttttt cttgctgctc cagagcctga taggccttgg
    28861 caagattcca tttagttagc acatgatcaa tctcctcatg ctcaagagca atgacctcct
    28921 caaaacgctc catatccaag tacaggctag ataagcgcat gatgacctct tcgtcatcaa
    28981 cagctacttc cttggccctg agcaaatacc gctctgagcc agctggatca tgcaattcaa
    29041 aggcaagctg tgaagcaagc aacagcagct gggggtcaaa ggcattttta cgcagaccct
    29101 gctgaactag gcgtaaggcc tcttctgtcc gatgctcctc acgcaagctc atggcatagg
    29161 ggtactcgta gcctaaaaag tctgcattca tcgtttctaa ttgcttgaaa tagagattgg
    29221 ccttttggta agcagcctga tcatataaaa tcgtcgccag ctcaaacact gtctcatcgt
    29281 catactcaat ggcaagagcc ttttcaagaa actctacagc agcttcaaat ttccctaaat
    29341 aagcataggc acgccctatg cgctggtagg ttgagatacc tgtcagctca agaatgtgac
    29401 gattatcaag cctagcatat tgctcaatag cctcgctaaa gtgctccaga gacatctcga
    29461 tttcggctaa gccaaagatc actatcggct cctgactcaa ttcagctgct tgaagtagct
    29521 tctcacgcgc cacatcagtt agcccctcca aatcataaag atcagccatg acgagcagag
    29581 cagacaaata atcagcacta tcctctggaa tcctatcaag gtacataaag gcctcttcaa
    29641 tgacattatc ctcagctgca atctgagcaa gattaatatt gacctccgga taagcctcac
    29701 agacctgcaa ataaatcgtc ttagcatgca gtaaaaaacc aatactctct aggtattctg
    29761 ccaaagccaa caaggtctca gcatcgtcct cctgcaaggc tctttgaaaa tagctttctg
    29821 cctgctctaa atcctgttgc tctagtgagg caatcatttt ttcactattt aacatcttca
    29881 gcgaccctct cagcttctgt aggctcttcc tcatacaggc ctgtaatatc cttgtaccaa
    29941 tcaaatagct ccttcacaac aaccttaaca gaagcataaa ctggaatgac aagaaagaca
    30001 ccccagaccc caaacattga ccctgctgtc aataataaaa acataatggt aatcgggtga
    30061 atgctcagct tatttccaag cactagcggc gcgacaaaac gtccttcaat cgtttgttca
    30121 ataacaaaaa taatcaacac cttgatcagc atcaagggtc cttgcaccat tcccataatc
    30181 actacaggaa tcatggctaa aaagctcccc agataaggaa tcatattaag aaagcctgca
    30241 ataataccaa aggtaataga atagttcaaa ccaacaaggc taaacatcac tgaaaacatg
    30301 agaccaacca caatcgcaac ggtcacctgt ccctgcacat agccagataa ttgcttgttg
    30361 atttctccta agacacgtgc cataggctgg cgcagcttaa tcggaagcac attgaccaaa
    30421 ccatttttca tatggccact gtcacgcaga aaataaaaga gaataaaagg tgacatgatg
    30481 attgcaacag taatacgggc aatagctcca gcaaaatttc ctgcccaatc aatagcattt
    30541 ttagagaagc tttgcgcata atctagagcc ttttggctca tactagtcag catatcctgc
    30601 aggttggacc tgtagctaac cagccattcg ttttcaagta gcttattagc ctctagattg
    30661 accttggcaa catatttggg aaggtcttcg acaaagctcc ttagctggtc ttgaatcata
    30721 gggataaagc cagaaatagc ccagaaaaat aggagaatta ctaagccaaa gacaataaaa
    30781 atagaggctg tgcgatttgg acctagcttc tcaaccatat caactaatgg cttggtcaaa
    30841 taatacagga tagttgagat aaccagcggc agcatgataa tggccaaaaa tgacaagatc
    30901 ggtgtaaaga ggaaggatat ttttgtaaag acaaaaatag tcagaaaaac cagcagcgtg
    30961 attaacaaaa ccatcaccgc ctgattattt aaaaaccatt tgtaaaatag actatcatga
    31021 tgattaggct tagaatgcaa tgacattaat ggtatcgtcc tttcttaatt gtggcatcat
    31081 tctgatgaga gcttttaggt tagttgactt aataaaaggt gactgttttt tccactagct
    31141 tgttgtggtc atcataccta aatttagcag aaaaaaacgg ccggtcttcc agtatccact
    31201 tgaaaatgtc gtaatctccc tcccaggttg gcttttccag cacctgatca tagggaaccc
    31261 attctagggt cccttctctg gactcctcat cagcaattaa gtcaccttca aagtctgtca
    31321 ccttaaacac gtaagtatac caatcatgcc ctggtgtaaa atcaggaaag gtaatcactc
    31381 ccttaaagtc cattgctttt accagcaggt gagtttcctc taaaatttca cgtctggcac
    31441 agtcatcagg agattcgcct ggctctaatt tgccaccaac tgaaatccac ttaccttggt
    31501 gaacatcatt ttccttcttg ttgcgatgca gcagcaataa agcctcaccg ttatcaatat
    31561 aacaaatcgt tgctaactta gtcattcata cccttccttt gtttagttgt tactattata
    31621 ccaatctctg agaaatatgc catcatttta tcatttaagc acatcaaaca agaaaaccac
    31681 aatcactaca actcttagcc ctgtactagc aaaaaagcct tgataaggca acgtctgctg
    31741 actcatcaag acttatcact atttaacgaa tcacttcctg tgtcttagcg taattggctt
    31801 caactgcttc tttttcggaa cgccaccaat cctgatgatc agtataccat tggatcgttt
    31861 gctcaagtcc ttctgaaaaa tcagtaaact gtggctccca gccaagctcc tgacgaagct
    31921 ttgtcgaatc aatagcatag cgtaaatcgt ggcctgcacg atccgttaca tggtcataag
    31981 cgtccttagg ctgccccatt ttatccagga ttaattccag cacttcctta ttattttttt
    32041 cgccgtcagc tccaataagg taggtctcac caatacgtcc cttggtcaaa atggcccaaa
    32101 caccagttga gtggtcattg gtgtgaatcc agtcacgaac attctttcct tcaccataca
    32161 attttggctt gataccagac aagatattag tgatctgacg agggataaat ttctcgatat
    32221 gctggtaggg accataatta tttgaacagt ttgaaatggt tgccttcacg ccaaaggagc
    32281 gaacccaggc cttaacaatc aaatcagagg ctgccttggt tgatgaataa ggtgacgacg
    32341 gattatagtt agtatcagcg gtgaattttt cacctggccc ctcaccatga cctggcaaat
    32401 cctcacgcag tggcagatcc ccataaacct catcagtgga cacatgatgg aagcgaatat
    32461 catatttacg agccgcctct aagagtgtat aagtcccaac gaagttcgtg taaataaatg
    32521 gacttgggtc attgagtgaa ttatcattgt ggctttcagc agcatagtgg acaatagcat
    32581 ctgccttagc ggccagctta tctaccaatt cagcatcagc aatgtcacca acaaccaact
    32641 ccacgcgatc acccaaaatc tcctcaaggt tggcacgatt gccagcgtag gtgagcttat
    32701 ccaaaacagt tacgtgaacc tctgggtgat ggttgtaaac ataatgtacg aagtttgaac
    32761 cgataaagcc agcgccaccg gtaacaataa tgtttttata ttcagacatg ttttttcttt
    32821 tcctttgttt tcagctatca gcactcaaaa tgcagcttaa tccgacaggc aagctcagtt
    32881 accagtgaaa acagcgacta agctgcctca cctcattgct cctaccatcc ataaggtcct
    32941 tcctatcaga aggatacaga gacactccca tcaaaagcca tagcttattt caaatgctaa
    33001 ttatgataaa tcttcttgtc tcaaaggctt aacggcctct aggaagggat ggcttttatc
    33061 tgcttctgaa acctctgctt gttcaagact ttcccacgca atcccaaggc ttgggtcagc
    33121 ataattaaca aaggcatatt tttgcttgag ctcaagcgcc caataatcat tgaccagata
    33181 ggtataagcc accttatcag tcagtacttg aaagccatta gcaacacctc gagggacaaa
    33241 aatccccttt gaagcgtcaa tgactgtttg ataggtatgc ccaaagctat caccctcacg
    33301 aagatcaacc caagctccaa gaaccttacc ctcatcagca acagagatgt acttgtccca
    33361 aggctctgca tgcaggcctc gaagcacatg cttgcgcgaa aatgaaatat tgttttgcag
    33421 cttacctgcg gcaaaaaact gctcaggaaa gcctagagga atcatttttt ccttttgaaa
    33481 attttcctta aaccagccac gattgtcccc tcgaacaggg atatcaaact ccaaaagtcc
    33541 aggaatggct tcaatttccc gacaggctaa ggctttatca aaaaattgtt ctgtcatcaa
    33601 gcttctccaa tcaaccgcag caggtactgc ccgtattcgt ttttcttaag cgactgcgct
    33661 agctggtaga catcttcttt agtgatataa cccatgcgat aggcaatctc ctctaggttg
    33721 gccacctgag cgttttgcaa gcgttgaact gtctcgatgt attgggcagc ctccagcagg
    33781 ctttcatgag tgccagtatc tagccaggca aagccacgtc ccatcaactc aaccgatagg
    33841 tcgccacgct ctaaataggc tttattaaca tcagtaatct caagctctcc tctggcactt
    33901 ggtttaatgc ttttagcaat ctcgactaca tcattgtcgt aaaaataaag gcctgttaca
    33961 gcaaaatgtg acttaggaac tgccggcttt tcttcgatag aaatggcatt catctcatcg
    34021 tcaaactcca caaccccaaa acgctccgga tccttgacct gataaccaaa aacagtggct
    34081 cctttttcct tagctgctgc cttttggagc attttcgtaa ggccgtttcc atgatagatg
    34141 ttgtcaccta aaatcaaggc aactcgatca tcaccaataa actcctcacc aatgataaag
    34201 gcctgtgcta agccgtcagg acttggttgc tccttgtagg acaagcttat cccaaactct
    34261 gagccatcgc ctaatagctc ttcaaatctt ggaagatctt ggggagttga aataatcaaa
    34321 atgtctcgaa tccctgccag catcagtgtt gataagggat aataaatcat tggcttatca
    34381 taaattggca tcaattgctt tgaagctgca cgagtaagag ggtacaagcg tgttcctgat
    34441 cctcctgcca gaataatacc tttcatcgta gctctcctca ttttataata cgtcactatt
    34501 ttatcatttt ttaaaaacag tgtcactttt tatcattaat ccgacgaata taatgatgaa
    34561 tcgggtattg actagtatct aagctagctt tttgccccaa aagcagggca atcagctgct
    34621 gagcaatcaa aggacctagg gtcaagccag atgagcctag accgcttgcg gcgtaaacac
    34681 ctggtagctg aggtacctgc ccaaaaaatg gagaaaaatc tctggtatag gctcgaatgc
    34741 ctacgcggta agaaacatca gaggcagaac tcagcttagg gtaataggtc aaggcctcct
    34801 gctccaaggc ctctaaaaca gctacatcag gctcaaggtc atagccctta tcattttcat
    34861 gactcgctcc tacagacaac ctatcatgct caaagggaat aatatccagc tccccctctg
    34921 gcatgaccac tgcgtagtta tctgtagtca cattcgcaat gtgataatca atgagctgtc
    34981 ctttttgcgg tcgaatatcc acctgatagc caagtggctc aagcaattct ggcagccaag
    35041 caccagcggc tagaatcagc cgatcaaaga ccataccatc aacgagatag ccttgctttt
    35101 ctatgcttat gccaacacgc tttttaacca cctgatagcc actagcttca agcaaacact
    35161 gacataggtc tgccccatca acacgtgcag ccccagaagc ccataccagc tgctcaaaac
    35221 cctgtaaatc aggaaaatca accctaatgt ccgaacgaca ccttatcgcc aaatctccaa
    35281 tcaaaggcga ctcttgcttg cgtctaatgg ccagctggta gagctcctct agcttgtcct
    35341 cattcttttt taataaataa acaccagtct gcttataaaa atgtgtagaa agcccctctt
    35401 tttgcagctc cttgattaag tcctgataac aatctgctcc taaccgagcc agctggtacc
    35461 aagccttatt ccttcttttt gaaaaccaag ggcagataat gccagcggct gccttagttg
    35521 cttgaccatt accatcatca aaaatagtaa cctgctgata cccttgtttt tttaaataat
    35581 aagcggcgct tgaacctaca attccagctc caatgattgc tatcgttgtc attgccgttt
    35641 ccattctatc atactgctta ccaagcatag gccatactca gtcatgctat agatgactaa
    35701 agggatttgt tgacgccttg ctagccataa tggttacttg ccagccttcc tcttttttcc
    35761 aagcctgcat cttggcaagt agtttatcaa taaataagga ctcgatgtga tgccctggat
    35821 caattgccag caggccttct gtcagcattt cctgtgctgt gtgataataa atgtcaccag
    35881 taatataaac ttgagctccc ttagcaagcg ctgcctgata aaatttatca ccactgcccc
    35941 cacaaatagc cactcgcgaa atcaaagggt tttgaccagt atatcgaacc agccgaacca
    36001 catcaagccc aaaggcttct ttaactgtaa gtcctaactc ctccaagctt tgctctgcta
    36061 catttccgac acgtccaata ccatacccat cttgcgtctc aaccaatacc tctgtctgct
    36121 caatgcccaa cagctcacaa aaccaatcgt tgagcccgtc agagacaata tctatattgg
    36181 tatgactgac atagacagaa atatcgtgct tcaccagctc aaggacaata tctcgctgtg
    36241 gcgaggagac caagtccttc aagcccttaa aaataggagc gtgcttggtg ataatcaggt
    36301 ctaccttggc cgcaatagct tcggcaacgg tattttctct cacatcaagg gtgatcatta
    36361 cccttttgac ctccttatcc agagagccaa tttggaggcc acacacatct cctgacatgg
    36421 atagctcaag cggacaatag ctttcatatt tttcgatgat tgttctagct ttcatgactg
    36481 atgacctcct caatcgcttt tattttttga gaaatgctag cgcgttcaac aggcttcgtt
    36541 gctggcacac aagacagggc atagacaagc ttatctcgct ctttttgcca tttagccaca
    36601 aagactgatg acctttcctg agacaagaaa ggaccaaagc gctgctcctg atctgttaga
    36661 ctttgttgac caggctctgc aacaatgatt tcataatatt tgccattttc tgtcatgatg
    36721 gtttcagcac taatacaaaa agcattggca gatagccaag cacgcagctc atcctctcga
    36781 ttattgggct gtaaaatcaa gcgctcaatc ccttgcagct tttccttacc agccgctaaa
    36841 atgtcagcta ttaaacgccc tcccatgcca cagatggtta tgcagtctac agcatctctc
    36901 gcctcaaagg cagctaagcc attagccaga cgcacctcaa tatgctctgt caaaccatat
    36961 tgtgacacat tttttagggc tgatacaaaa ggtcccttga ccacctcacc tgcaatcgcc
    37021 tcttgaatat gctcggtttc aaccaaaaaa ataggaagat aagcatgatc acttcccacg
    37081 tctaaaagct tagcaccatc agggacatag gatgccacat ggcgtaagcg ctttgataaa
    37141 tgactttcca ttttcttaat ccttctaaca actaatcgta tcactattat agcaaaatac
    37201 agaccaatta aaaagaaagc cacatcagac cttcttttta ccataggtag tcttgtaata
    37261 gctgcaatag ctctgtactg ggcaggtatc acacttagga tgcttagcca agcagtgata
    37321 gcgtccaaaa aagatcaaac ggtggtgggt gatgatccaa tccttcttag gaagcttggc
    37381 catcaaatca gcttcaattt cagtaacatc ggcatctggg gcagaaatgt tcaagcgctt
    37441 ggcaatcctt gacacatgcg tgtcaactgc gattgcaggg acaccataaa tctctgccaa
    37501 gaccacatta gcagtcttac ggcctactcc tggtaaggat tcgagctcct tatgggtttt
    37561 tggtacctga ccatcaaact gtgtcagtag ctgctgagct gtcttgatga tattttttgc
    37621 cttattttta tacaagccaa ttgtccttag gtgatcctca acatctgaca catttgcctg
    37681 agccaaatct gaaagctctg ggtagctttg ccacagctta ggggtaacct tgttgactgc
    37741 cttatcagtt gtctgcgctg ataggataac cgtaataaga agctgaaagg gcttttcttg
    37801 gtcccaattc agctcgccct tagcctctgg aaacatctca ccaatgattg atagaacctt
    37861 ttttaatcgt tctcttccta tcctcattag ttactccaaa ggttcatcgc cgcaagaaaa
    37921 tcatctgaaa ccgtcacttc agacgccgtc atatcctctc tggcacgctt tttttcctca
    37981 agctgcctga ggcttgtaat tccctccttg cgccaatttc ttagaatagc ctgaatatat
    38041 ttccaattgg tttttccatt aaagacagcc tctctcagcg cctcacgcac taaatccaga
    38101 tctgtttggt catcatgaat ggttttttcc aaatcctcta gctccatcgg actcaaaaaa
    38161 cgacccagct cacgctcaaa ctcatcaaca agaagtttca attggttggt gttttgctgt
    38221 tcatgctcac ccttttcatc acgcgccaat agctggtcta aagtgactaa tacaggacta
    38281 gcatcaaaaa tgatctcaat ctctccagcc agctctatgg ttttcatatc taataacccc
    38341 tgactggtca aggaagaaat agccttattc acctctgcta cagacttacc caaggcatta
    38401 gcaatctgac taggtgccaa ttcgtcaagc ctagtcgtat tttggagata gaaaaactgc
    38461 caaaccaaaa aatcgtctga gctcttaaaa atatccttgt aatgaaacag taaggcagtt
    38521 ggaaggacca aattgccaga ctgataatgc tctaaaaaac tcataattcc cctgccaaac
    38581 gtaatagccc aacctagctt ttaatcagta ctgccattag caagcactga ttaaccagga
    38641 aaatgcatca ataccttaca atcgtaatca ccaatagcct gacgaccatt caagccgtcc
    38701 agctcaatga gaaaagcgca gccagcaaca atgccgccca gcttttcaac cagatcaata
    38761 gtagccttta ctgtaccacc tgttgctaat aagtcgtcca caataaggac acgttggccc
    38821 ggcttaatag catcagcatg catggtcaag gtgtctagac catactcctt ttcatagcta
    38881 gcagaaatca cctctcttgg caatttaccc ggcttacgaa caggagcaaa gccaattcct
    38941 agctcaactg cgaccggaca gccaataata aagccacgag cctccggtcc aacaatcatg
    39001 tcaatgtcct tatcgcaggc atattgcaca atctcacgaa tagcatagct gtaggccttg
    39061 ccactagcca ttagcggcga aatatcacga aaggtaatcc cctcctttgg gtaattctca
    39121 attgaagcaa tatattgtgt taaatccatc gtaaaatagt ctttctaatg tcttttaaat
    39181 taaaatcttt cctattatag catgaaagtc taaaaaggta aatgattcct aatcatccag
    39241 atcaatccct ttttccttta aattagtcag gcattcctgt aaataggcct cttgatgctc
    39301 aggataaatc ggtgaggtca gtgccacctc ctctaagtcc tcataggcgg caaggctttt
    39361 tcctcggtaa tttttatcct gccagctcac atctggctgg tagccccgcg cctgcatttc
    39421 ctgcataatc aacaggtgat actggtaaag cttataaaga gaatgggcaa acacatagtc
    39481 aaccgtcgca tgtggtctcc cccagcctgc tcctcgcaag gccgcacatt cacgatgctg
    39541 ccccaacaat tgctgccttg gtaggcgtgt gattaaatcc tgatgccaaa gacgcataag
    39601 ctctcctatt tctcttcact agtcattaaa tactgataaa tctcctgcgg actgcccaag
    39661 gccataagct cttgaaactt taccagctct tttagctgtt ggtaaatgac actgtcagcg
    39721 atgctacgtt ttggggcatc agtctttacc ctcatcagcc catcttcgat tactacaaag
    39781 cctaactcct caaaaatttg tatcattttg accaagagga ttttttcaat cttgaggtaa
    39841 tcacttagca aggtcagctt atggcgaaga tcaaattctg ggtattgata gatggtctta
    39901 taaagcttgg caaattgctc tctactgcca tagcctgtta ggtaataagg gcgcttaata
    39961 tgatttttaa agtaaatcgc ttcaaattcc cgatgtctaa aaaggccttt caaggcatca
    40021 atatcgtcag gaacctcatc tatgacaaca accttggcct gctggtcctc aacagctgta
    40081 ggaatatgct caggtgccct agcagtcctt gctcgaatat caaacagctg caccccagtc
    40141 actctagcgt caaccagcat taattgcagg ctagtatgac ctcgccagtg attgatcgca
    40201 agactaaccg ctaattccaa gccctgtgat tgctggtact cctgtatcag atgtccctga
    40261 ccaaaggcca agacatcagc ctcaacggct cctttgctga ccttgaactt caagtgactt
    40321 tgttgctgac caatggtcct tgcctgctta atcgtaaaat cttttaagta aaaaacaggc
    40381 tttttattat ccatgccaaa gggtgctaga agtagcagct tgttcagact atctatactc
    40441 aatgcttcta aatccaattc accattgatc aatagagtgt ttttttcctg accatcgtgt
    40501 cccttggctg ccacgtattg gcaaagtagc tctgatagct cctctaggcg atcagatggc
    40561 agagtcatgc ctgctgcccc ctcatgacca ccaaaggctg taaataagct cctattgcta
    40621 ttaagtgctt caaagatatt aatgctctct aagcttctgg ctgagccctt ggctagcccc
    40681 tcatcaatgg tcaaaacaag aacagtctgc ccaatctcct ccatgatccg accagctaca
    40741 atccctaaga cccctgggtg ccagccagac ttagctaaaa cctgcacagg cttgtctaga
    40801 tcaagcatag ccattgcttg agcaaaaatc tcctgtacca agacctttct ttcctcattt
    40861 ttactactaa tcatcaaggc aagctcatga agctcttcgt catcaaagcc tgtcagtaga
    40921 tcaatagctg gatttggatc gtcaagacgc cctagagcat tgagctgcgg agcaagctta
    40981 aagctaataa catcttcatc aaaatgcgct aagtcaacct ctgaaagctt catcagctcc
    41041 tgcaagccta gtctttctgt ctcttttaga acagccagcc cgtttttgac aaggatacgg
    41101 ttttcacctc gtaggctgac catatcagca attgtcccaa tagcaaccag atctaaaaag
    41161 tctactggaa ttgtctctaa cagagctgaa gccaacttga aggcgacgcc acagccagct
    41221 agtttttgaa agggataagc agcagctggg tgctcagggt gaataatagc aaaggcatca
    41281 ggtagctctg ctggcaggct gtggtggtct gttacaataa catctacccc ctgtgcttgc
    41341 gcaaaggcaa ccgcttcatg gcctgaaaca ccattgtcaa cggtaataat cagcgaaacc
    41401 tgctcttgct cgatgaaata cttgtaaaca ctttgattgg gaccatagcc atctgtaaag
    41461 cgattaggca aataaacaag aggctctgct cccatcattt ccagcgtttc cttgacaata
    41521 gacgccgctg tcatgccatc tgcatcataa tctccgtaga ccaaaatcct ctcaagcccc
    41581 tcaatggcct gacgaatgcg atgaacagct ttttccatat catttagcaa ataagggtca
    41641 tggagctgtg ataggtcagc tgtcaaaaag ctggtaagct cctcttcggt atgaacacct
    41701 cggtcataga tgagctttgc agctgtctga ctaagtccct ttgcctgagc tagcttaaag
    41761 aagccagcat ctggctcctt atcagctatg gtccactgat atttggacgt aatcatttat
    41821 aattaaatac ctttcttgca agataatcag atatagttgg aaacaaggta taacacttat
    41881 gagcaagggc taggctaata ggcagattaa tctctcgttt cttttttcct attgcagcaa
    41941 tgattttttt cgccacagta tccgcctgca gcgtaaagcc tgcaacactg gctaaatact
    42001 gcccgcttgg gtcagcctgc tcaaaaaagg aggttgcaat cgggcctgga ttaacagttg
    42061 tcacataaac ctgcctttct gccagctcca agcgaagggc attagaaaag ccaatgactg
    42121 caaactttgt cgcagaatag atacttgact tggcagaagc tattaagcct gccattgaga
    42181 caatattcat aatatgtcca gagccctgct ctgccatttt gtggccaagc aagcgtgcaa
    42241 aatgaatgct ggctaagcta ttcacacgaa acatggcctc aatctcttct gcagagaaat
    42301 catcaaaggc cttaaaagca ccaaagcctg cattgttaat caaaacatca atcctgccat
    42361 ggcgctggta aagctcatca acaagagcct caatagcagc agggtcttga atagcaatct
    42421 cgtagcattc cttattaccg cgagcctgat atagactgtc taacctgtct ttgctgcgcc
    42481 ctaacaaaat caggtaatct tctcttggaa gctgtctgat gatagcctgt gcgagcccgc
    42541 cagaagcacc tgttatcaga ataattctct gtgccattaa atgatcactt cctctaaatc
    42601 gcgaacaacc ttcacatttt caaaaatagt tgccgcatcc ttttccattt gacgacagtc
    42661 acgtcctaaa aagcgtgctg aaacatgatt cagtaaaaga cgcttagcac ctgcatcacg
    42721 cgcgatttga gcagcctgca tgtttgtcga atgcccatga ttacgggcca ttctttcatc
    42781 acccttcccg taggtggact catgcaccag cacatcagca tcttttgcca atctaacact
    42841 agcagatgtc ttgcgtgtat cgccaataat ggtgatgatc tttccttttc gaggctctga
    42901 aataaagtcc ttggcaaaaa ttttggtgcc atcctctagc tcaatatcct gcccattttt
    42961 aaccttgcca aaaagtggac caaagggcac tcctactgct ctaagagctt ctgcatcaag
    43021 tgttccttct aaatcctttt gaaccacacg ataccccata caaaagatgg tatgtgccaa
    43081 gcgctcagca taaacaataa atttatctgt ttctaaaatc ttgcccatag aggtgtcatc
    43141 aaactcatga taatgaatct gataaggcaa tttagagcct gatatcctga tgctgtttgt
    43201 tacataggat tttatcccaa caggtccata aatctcaagg tccgtctgct cctcactagc
    43261 ttgaaaagcc cgactagata aaaagccagg caagccaaaa atatgatcac catgcagatg
    43321 cgtgataaaa atcttcttga tttttcgtgg cttgattgtt gtttctaaaa tttgccgctg
    43381 ggttccctcg ccacaatcaa acatccacac ctcattgatt tcatctaata gctttagcac
    43441 taagcttgaa acgttgcgat gcttggctgg ctgcccagct ccagtaccta aaaattgtaa
    43501 ttccatacag tctattcttt ctaatgcaca aggtaaatca tgaattctct ttgtgcaaac
    43561 tgataatatt tctttccttt gaatgcttgg ctaagagcca acaattcatc actattaaag
    43621 ccctttagca gggtcatttc gtttgagaaa cgatagatcg tggttaacaa agcatgctca
    43681 ggtgttatgt cctctggctc tccttgctca aattggcagc tcttcatctt gattctacca
    43741 tcttccacat aaaccacgta ttgtggaaaa atctgagcca gctccagcag cagcgattcc
    43801 tcaggctgcc cctgctcttt ttcagcaaaa acaatcgcct cctgtgcttc attttcaaag
    43861 acaaagccat aggattgccc caacaaattt aagcggacaa agggcttcac ctcatcaaat
    43921 gacggctctg aggtaaacag cttcaaggcc cttgatagct caaaataata atctgtcgct
    43981 gcttttggtg attgcttctg atacatttct gcaaaataag cattaatcac acttgggggt
    44041 ggcgtgatgg tagctaattt ttgctggtct gtcaagccct ttaagcaatt ttgcaaataa
    44101 accgtatcta aactcgtaaa gcctccataa gtctttgcca attgaatata atcagtcata
    44161 aaattcttct aatctccatt tatttttggg agcaatgtag ccagaaatct cttcaatctc
    44221 cttatcaaag ctataaggct ccaataacgc caacctgttg aggtcatagc atttgtaggc
    44281 ttgatcctga cagagcttga tcgaaaatgg ctcaaacatg tcccgaatct gatcaataag
    44341 caactgtctt aagaggctac gactgttttt atcacgtgct gacagcctga catttggaaa
    44401 aacagttgca gtcaagctag ctgtcttatc catcttgtta taaatagcca gccttggaat
    44461 atccagcata tctaaatctt tcaagatgtc tagaacaacc ctctcatgct ccaaatgatt
    44521 agggtcactg gcatcaatca catgcaagag caaatcaaca tgccgacttt cctctaatgt
    44581 cgacttaaaa gcagccacga gctccgttgg taaatcttgg ataaagccta cagtatctgt
    44641 cagagttgcc tgaaactgat tttgcagata aatttgcttg gtggtggcat caagtgttgc
    44701 aaataattca tcagcctcat attgcttgtc accagtcaaa atagtcataa tagtagactt
    44761 acctgcattg gtatagccga tcaatccaat attaaagaca tcagaggtca tgcggcgatc
    44821 acgaatcgtt tgacggtttt tttcgacagc agctagctgc cgctcaatat ctgcaatctg
    44881 atgacgaatg gagcgccggt tcagctccag ctggctctca cccggcccac gactcccaat
    44941 gcccccggcc tgacgactaa gcataacacc ctgtccgacc agtcttggca gcatgtattt
    45001 gagctgcgct aaatgcacct gcaattttcc ttcatggctt ctagcccgca tcgcaaaaat
    45061 atcaagaatc agctgcatgc gatcaatgac cttaatacct aaggcgtcct ccaaattggc
    45121 attttgccga gccgttaaac gattgttaac aatcactgta tcaatctcat tggcagcaac
    45181 catttctttg atttcagcca gcttaccaga gccaacaaag gtcttgctat catagcgctc
    45241 cctcttttgc agatagcaat caacgacctc tgcacctgcg gtcttggcta gactagccag
    45301 ctctgtcatt gatagctcag catggtcagc tgcttgtagg accacgctta gtaaaataac
    45361 tctttcctgc cttgcctttg tctctatcat gaacgcgact aatcctccaa attccgtagt
    45421 gtttattata gcatagtttt agctattttc agctagtttg ccatcgatag cttcctaagg
    45481 ctccttcaaa aagcgctcca ccctatcata tattgcctgc ggataggacg actcgctaat
    45541 cgagtcaaag cgcactgcca tacggttacg aaaccaagtc agctgtcgtt tagcaaagcg
    45601 gcgtgtttgc tgctttagtg tggctgttgc ttcttctaaa ctagcctgac cctgaaagta
    45661 agggaagagc tccttataac cgatccctcg actagcctga acagctggat actgctcaaa
    45721 aagccacctt gcctcctcca ataggccaga agccatcatc agatccaccc gcttattaat
    45781 ccgctcataa ataacctctc gctcatcagt caagccaatg atcaaggggt tatagggggc
    45841 ctcttgattt tctaaatccc tagcaaattg atttagctca agtgagcgaa tggcacgcct
    45901 gcggttaacc tgatcaaggt gaatgccctt actagctaat agctgataaa gctctgtatc
    45961 tgtcagtgtc tctagctgct gccgataagc aagtagctcc ttttgatcaa gatctcctcc
    46021 tagatgatag ccctctaaca ggctttgcaa atacaggccg gtaccaccga caataatcgg
    46081 cagtttaccg cggctaacaa tatcttcaat agctcgctta gcgtcctgca caaaatcaaa
    46141 ggctgagtaa gactctgtca cctcacgaat gtcaatcaaa tgatgaaccg caagagcctg
    46201 ctccctggca ctagccttag ctgtcccaat atcaaggtga cgataaacct gctgactatc
    46261 tccagatata atttcaccat taaaggcacc agccaaggca atccctagag ctgtcttgcc
    46321 aacagcagtc gggcctacaa tcacaattat cttttctttt gtcatttatt gtctttctac
    46381 ttaaaaagca gctgaaaaag tcttttactt gaattttcta atctttttcg ctaccatata
    46441 ttataacata agattgagag acagttatgg tcctcttaat agaaatggag aatgattatg
    46501 gctaaaaaac atggattcgc aaagggtctt gctacaggtg ttcttgctac tgctgctacc
    46561 gttgcaggtg cagtatttgc tgttaaaaag actattattg accctgagga agaaaaagca
    46621 gcatttgtag aggaaaatcg taaaaaagca gcacgtcgtc gtgttgctcg ctaatcacta
    46681 atagatgaaa gattcgacag gctttatcaa tagcctgtcg aattttttat gctgtgagac
    46741 caagcttttt gcttagacac ataaaagaaa cagctcgtca gcgccgcata ctgcctactt
    46801 cattgaccaa caaacagggc aaactaaggc taattttcac tgatatgaca tgtttcgact
    46861 ataaagcggt tttgtgattg attgatcaca atatcaaatt gctggtgata agggtgcaga
    46921 taacgagcat attgagcgcg cctattgaca tgatgaactc cggattgcga cctctaatgc
    46981 tagtatctct accaagccgc ctttggagct ctgtgtcacc atctgtataa aagtaaagcg
    47041 ataagtcaaa caactctggc tctaaaaagg ttgtcgacat gccttcagca ataaggatgg
    47101 gcacattccc cttcaccaaa aaagagggag accaaggggt atcaatactc aaaaaatcca
    47161 gtccttgctt aaacatcatg atgtcacgcc tcagactggc caattcgtgc ctagcagggt
    47221 gacaggctgt tatactacca agtacctcct ctccctgatc agggtagcta atcaaaacag
    47281 cctgactaaa atcattagcg atgatatagg catctgtttc taacaattgg ctttgtccat
    47341 caggcaaaag ctgctgtaag cgcttagcaa aggttgattt accagatgca ccatgaccac
    47401 taattctaat aagcattttc tcacgattgg ctgctgcagt tacaatagct tgaagtagct
    47461 tctccattat ctctcctcat caaataacat tctaataata ggacatcatt ctacatcgaa
    47521 aaacaagccg gtctcccgaa acagcctgac tgacagtaaa aaaagattga agggcaatcc
    47581 aataaggaaa gcttctccaa tctgattaat agtctataat ggcttaatat gagtgccaaa
    47641 tgtcttggtt atattgttca atcgtacggt ccgatgaaaa gaagccagcc ttagcaatat
    47701 tatgcacaac ctttgtcagc cataggtcct gattgtcata atcagccagc atttgttctt
    47761 tgactgcaat gtattcctca aggtcaatca aggtcataaa ccagtcctta gagattaact
    47821 ccttatagag acggtcaaga cgttcctcat taccaagctc taataattct ggactgataa
    47881 taaagttaac tgcttccttg atagctgggt gggcatcata atagtcttta gacacataac
    47941 cacctgtggc ataaagatca ataatggtat ctgaatcctt accaaaggtg tagatattat
    48001 ccataccagc aagctcagcg atttccacat tagccccgtc catagtacca agcgtcaagg
    48061 caccattgag catgaatttc atattaccag tacctgaagc ttcctttgaa gctagagaaa
    48121 tttgctctga aatatcagtt gcaggaatca aatgctctgc tactgtcaca ttgtaatttt
    48181 caacaaggtg aacattaagg tatggactta cctccggatc gttattgata agctctgaca
    48241 agcaaagaat caaatgaata atatcctgtg caatgatata agccggtgca gccttaccac
    48301 caaagataac tgttatttta cgcttcggca ggttgccttt tttgatctct aagtatttat
    48361 gaatcacata aagggcattc atctgctggc gcttatattc gtggaagcgt ttaatttggg
    48421 tatcaatgat tgaatgctca tcaagctcaa ttcccttatt atccttgagg tagcgcttta
    48481 aggctacttt attatggtgc ttaatttcag ccaatcttgc atgaacagct tgatcctcag
    48541 caaaggccat taatttttca agccttgtcg catcagtcaa gtaagcatca ccgataagct
    48601 ctttaatata gtccgccaac tcttggttgg cgaattctag ccaacgacgg aaggtaatac
    48661 cattggtttt gttgttgaat ttttctggat acagctcata gaaggccttc aattcgctat
    48721 ttttcaggat ttcagtgtga agggcagcaa cgccgttgac acttgtggca aaatgaatat
    48781 ccatatgtgc catatgcacg cgacctgttt catcaatgat ttggacagct ggatctgata
    48841 cccttgcacg aacaagagca tctaattgct cgataatcgt taccagctgc ggcacaacct
    48901 cattaaggaa gtcaagaggc catttttcca aggcttctgc aaggatcgtg tgattggtgt
    48961 aaccatccat cttttgaacc actgaaacag cctcatcaaa atcaaagcca tgcttttgtg
    49021 tcaatagacg aatcaattct ggaatgacca ttgatggatg ggtatcattg atctgcacgt
    49081 atgcgtaatc agctaagtca tgcaggtttg agccacgctc aagcgcttca tcgatcaaga
    49141 gctgagcggc attagatacc atgaaatatt gctggtaaat gcgaaggagc tcaccatttt
    49201 tatcagaatc atcagggtaa aggaacaggg tcaggttttt ggcaatgtca gtcttatcaa
    49261 atgaaatgcc atctttaatc aagccataat caaccccttc aatatcaaaa aggttaagat
    49321 agttcttggt gtcacgctta tagcccaaaa catcaatacg gtctaagcga gatttcaggg
    49381 taaagttttt aaagggaaca tcatatgaaa tgtcagtcgg tactagccaa gagtcatcct
    49441 ctatccaaaa attaggctct gctgtttgtt cattgtgtct aaagacctgc ttgaacaagc
    49501 cacaatgata attcaagcca accccttcac cattaatgcc aaggcttgag atagaatcaa
    49561 taaagcaaga agccaaacga ccaagaccac cattaccaag cgatggctcc aattcaacgt
    49621 cctctacctc agcaattgat ttgcccgcag cagccagctc ctctttgatg tccttataaa
    49681 tacctagatt aatgagatta ttagaaagca acttaccaat caaaaattct gctgagatgt
    49741 aataaacctt acgtttagct gtgttttttg cttttttgct tgcttcttct ttgagatagg
    49801 aaagcaacga aagatagatt tcctcgttgc ttgcacttgc aagagatttt cctaatgtca
    49861 tttcagtata atctgtaaag cgtttcatga tatcctcttt tcaatatagt attctagtga
    49921 tgattattgg ctcgaccgta tagctcagtc aaatggatta aataggcctt gtgctctgct
    49981 ttaatatcgt cctcaagcat gcgccactgc cagttgccac cgacagtgtt tggcatattc
    50041 atgcggctat cagctgactt atccagcaaa tcctgcatac acaggatagc agtatcacac
    50101 acagtcgcaa agattgttct tagcatggcc ttggtgatgc tttcagcagc tgccttatgg
    50161 atataatgat taacaaactc aacctgctct gcgctcaagt gctcatacca gccattcacc
    50221 acctcattgt catgcgtacc agtgtagaca atgcaattgt gatcatagtt atgcggcaaa
    50281 tcaaagcttt gacttgtcac atcaaacaaa ccaaactcta aaatcttcat gcccggaaag
    50341 ccagtagatg ccagcagctg ctcagccttt tcatcaatgt agccaaggtt ttctgcgata
    50401 attggcagct cacccaaggc ctctcgaaca gctttaaata gagcaatacc aggagctgac
    50461 tcccaatgac catttttagc agtcacatca ccaccaggaa tttcccaaaa atctgagaag
    50521 cccttgaaat ggtcaattct aagcttatcg tacagcttga agctctcttt gatccgatgg
    50581 atccaccaag caaagcctgt ttgctcatgg ctctcccagt tgtaaatagg attgccccaa
    50641 agctgcccgt cctcactaaa gccatcagca ggtacacctg caatgtaaat cggcttttta
    50701 tctgcatcca ccttaaagag ctctggcatc gtccaaacct caacgctatc agcagacacg
    50761 tagattggca tatcaccaat gatagtaatg ccattttgat tagcataggt cttcagcgct
    50821 agccactgct gataaaagaa atattggcag accttatgat aggtgatgcc tttggccaac
    50881 agcttgcggt aatgaagcaa ggcagcctct tcacgcttaa caattgctct atcgtcccat
    50941 tcctggaggg ccttgtgatc aaaatgctct ttaatagcca taaattcagc aaaatcattt
    51001 agccagctcg cagttgcttc aaattcggcg agctgtctta agccttcctc agttgagaca
    51061 aaagcctgaa ctgctttttc taataaaggg cgtctggctt gaaagacttg agcgtaatca
    51121 acagactccg gatttgagcc aaaatcaaca gcagcataat cagcttcctg caaataaccg
    51181 tcctttgcca gcaattcaag gtcaataaaa tgcgtatttc ctgcaatagc tgaaaaagat
    51241 tgataaggag aatctccaaa gctagttgtt gttaagggca aaatctgcca ataggtctgc
    51301 ttggtttcct ttaaaaagtc aacaaattca aaggcctctt taccaaagct cccaataccg
    51361 aagcgtcccg gaagcgagct gatatgcatc agaataccac ttgcacgttt agtcattctt
    51421 tttttctcct tgtaaaatct taatgttgaa attataacgc aaccgtttgc gcaagtcaat
    51481 atcttttcaa aaaaaaagag actttttcgg catgctagag ctgctcaagc cttgataata
    51541 atgagggaag cagctaggac aaaaacaaaa aaaggattgg agagacagcc taagcagctg
    51601 ctcttccatc ctcatctcac tcctatttgg cattaatatc cctgacactc tctcgctttt
    51661 tgaggctaaa gggaaccaaa attttctgac tcagggtttg ttcattggca ttgataatgt
    51721 ctaagagctg cctaaaggag gttcttccca aattttcaac gttaatatca aatgttgtta
    51781 agtaagggtg aatcaatttc gaatagctag aattattaaa ggtaataatc gaaatatcat
    51841 ctggcacctt aatgtcataa aaggacaaga gctggaccat tcgcaccgac aaaacatcac
    51901 caatcacgat taaggctgtg gccttaaagc tacgtatcgt ttcaataacc ttttcgatgc
    51961 ttattggatc ctttcgatca aataacagca tcggtttgtt ttccaaggat aatttcaagc
    52021 agcccttgag atagccaata tagcgctcag aagctacctc tgcctccata tcgtctgtga
    52081 taaacaggat ctgtcggtga cccttttgat agagatgatc aactgcggtt ttagccatta
    52141 gctggttgtc attgtcaata taggtgattt tgttctcatc accttctggt gcgccaacaa
    52201 tgacaaaagg aatctggttg gtcatcaaat agcctctaac aggatcttct tgctcagaat
    52261 ataatataat aaagccatca acacgctttt gcaggtgcat taacttaacc tggctcaata
    52321 aatcctcaac agacatacct gttgcaatgg aaacagtgaa atgatgtttc ttagcttcat
    52381 tggtaatggt cgatagaatt tccataaaaa agggatcact caaacgatca ttagtgataa
    52441 tcggcggaaa aaccaggcca atattatgtg tcaggccact agcaagcatt tgcgcagcta
    52501 cattcggaac atagccaagc tcgctcatag ctcttctaac cttttccttt gtcttttggg
    52561 agatagatcg attatccttg aggacacgac tgacggtcga aggattaaca cctgctttta
    52621 aggcaacgtc ttttattgta accatataaa cctcatttaa tacctgataa tgacgctatg
    52681 tcaggctttt tcacatgtat tttgctttta ttatacaatt atctcctaaa aaatcaactc
    52741 tcgccctgca agaaggcgac ataaaaaact gctgtcctca tgatcgaaaa aatgttaaaa
    52801 aaatcaactt tttttaaaaa aagactagac tttttctgta aacggttgca taatattaag
    52861 tgtaagaaat atatcttagg aggaaatcgc tatgaaatca tggcaaaaag ttatcgtcag
    52921 tggggcaagc ttgacacttg ctagcgcctt attagtaggg tgtgcatctg gttcaaagga
    52981 caaaacagaa actgcatcag gtactgattc aaaaacaatt aagctttggg taccaacagg
    53041 agctaaaaag tcatacacag atgttgtcgc taaatttgaa aaggactctg gctacaaggt
    53101 taaggtgatc gagtcagagg atccaaaagc acaagaaaaa atcaaaaaag atgcttctac
    53161 tgctgccgat gtcttttcac ttcctcatga ccagcttggt cagctcgtag aatctggcat
    53221 tatccaagaa gtcccagagg aatacactaa agagatcgct gatacagcaa ctgatcaagc
    53281 tatccttggt gctcaataca agggtaaaac ctatgccttc ccatttggta ttgagtcaca
    53341 ggttctcttc tacaacaaaa ctaagctagc tgctgatgat gttgcttcat acgataccat
    53401 cacgtctaag gctaccttcg gtggtacctt caagcaggct aatgcttatg ctactggtcc
    53461 attgttcatg tctgttggta acacattatt tggtgaaagc ggtgaagaca ctaaaggaac
    53521 taactggggc aatgaaaaag gggttgctgt tcttaaatgg atttcagacc aagcctcaaa
    53581 caaaggattt gttaacttag atgccaacaa cgtcatgtct cagtttggag acggttcagt
    53641 tgcttcattt gaatcaggtc cttgggatta cgaggcagca caaaaggcta tcggtaaaga
    53701 aaaccttggt gttgctgttt atccaaaggt aactatcggt ggcgaaaccg ttcaacaaaa
    53761 ggccttcttg ggagtgaagc tctatgcggt taaccaagct cctgctaagg gagataccaa
    53821 gcgtatcgca gccagctaca agcttgcttc atacctaaca aatgctgaaa gccaagaaaa
    53881 ccaattcaag acacgtaaca tcgtaccagc taacaagacc gttcaagctt cagaggctgt
    53941 tcaatcaaac gagcttgcaa aaacagttat cacaatggga tcttcttcag attatactgt
    54001 tgttatgcct aagcttagtc aaatgggtac cttctggact gaaagtgctg caatccttag
    54061 cgatgccttc aatggtaaaa tcaaagaagg tgactacctt gctaagctac agcagtttga
    54121 caaggacatt gcagcaacaa aataagctat ctcatttata atactatcct aaacaagtac
    54181 agaggtgggc tattttaacg ctatcctttc tactcatctc taaaggggtg gaactaagca
    54241 tcattatttt ttcagggctt agtccactcc tacttgtttt tgatatgacg taaagcttgg
    54301 tgctacttaa atttttaatc gcttaaagat ttaggtaaca cttagctatg tggtcgttag
    54361 caccaaacgc ttatgaccac agcatctgaa caagagagtc aggtaatcct actttcttgt
    54421 atcctaacat aaaggagaac atatatgact caggcaggct tagcatctca ggttactgta
    54481 aaagaggctt taacaaaggg aagcttcgat attaaactat ccgctatcat catgggcttt
    54541 gccaattttg ctaataaaca attcgtcaaa ggaacactct ttttattgag tgaggtggtc
    54601 tttttcatcg cctttgtttc acaaatcatt cctgctattg gcggcctcat taccctagga
    54661 acacaaacac agggcatgac aaccaaaact atcgacggta tcagcattca ggttgctgtt
    54721 gatggagaca attcgatgct aatgctgatt tttggcttag cctctctgat tttttgtttg
    54781 ttatttgcct atatttattg gtgtaaccta aaaagcgccc gtcacctcta catgctaaag
    54841 caagaagggg caaaaatccc aagctttaag gaggattttg ttagtctagc aaatggtcgt
    54901 ttccatatga ccttgatgac aattccattg attggtgtgc ttctgtttac ggtacttcct
    54961 ttgatctaca tgatttgctt agcatttact aactttgatc acaatcacct cccgccaaag
    55021 tcactttttg attgggttgg tctttccaat tttggtaacg tgttaagtgg tcgtatggca
    55081 ggaaccttct ttcctgtttt ctcatggaca ctgatttggg ctgtctttgc cacagtgact
    55141 aacttcttct ttggtatcat tttagcactc ttgattaata ccaaaggctt aaaattgaaa
    55201 aaaatgtggc ggaccttctt tgtgattacc atcgcagttc ctcagtttat ttcactgctg
    55261 attatgcgaa atctgctaaa tgaccaaggt cccttaaatg ccctgcttag caaattaggg
    55321 ttaatccacc attctctacc gtttttatct gatccaattt gggctaaatt ctctattatt
    55381 tttgttaata tgtggatcgg tattccattt accatgttaa tcgcaacagg tatcattatg
    55441 aacctgccaa gcgaacaaat tgaggctgca gagattgatg gggcaagtaa attccaggtc
    55501 ttcaaatcaa tcaccttccc tcaaatcctc attatcatga caccaaacct gattcagcaa
    55561 tttattggaa acatcaataa cttcaatgtg atctatctct taactggtgg tgggccaacc
    55621 aattcagcct attaccaagc tggaaccacc gatctattgg tgacttggct ctataaattg
    55681 actgttacag cagcagatta taatctagcc tctgttattg gtatcttaat ctttaccgta
    55741 tcagcaatct ttagcttact ggcttacaca agaactgcat catacaagga aggagcagcg
    55801 aaataatgaa aaacaaacgt cgatttcagc ttggattagt ttacgccatt ttaaccgttc
    55861 tctcaatcat ttggctttta cctatcgctt gggttgttct gactagcttt cgtgctgaag
    55921 gcactgctta tgtcgattat tttcttccca agcacctcac attagaccat tatattaagc
    55981 tctttacaaa tgaaacattt ccttttggga gatggtttgt caataccttt gttgttgcta
    56041 tctttacctg tatcatctca acctttatta cagtggcgat ggcttactcg cttagtcgga
    56101 tcaaattcaa gtttcgcaat cgtttcttaa agcttgcact agtgctaaac atgtttccag
    56161 gctttatgag catgattgct atctactata tcctaaaagc acttggcctt acgcaaagtc
    56221 ttaccgccct agtccttgtt tattctgccg gtgctgcact tggattttac attgctaagg
    56281 gcttctttga taccattcct tattcgcttg acgaatctgc catgattgat ggggctactc
    56341 gtatggatat tttctttaag attaccctac cgctatcaaa gccaatcatt gtttacactg
    56401 cactccttgc ctttatggga ccttgggttg actttatctt tgcccaagtg attttaggag
    56461 atgcaaccag cagatatacg gtagctatcg gactcttttc aatgctgcag cctgacacca
    56521 tcaatgactg gttcatggcc tttaccgctg gatctgtgtt aattgctatt ccaatcacat
    56581 tgctctttat gtttatgcaa aaatactatg tagagggcgt tacaggtggt tctgtcaaat
    56641 agcagtaatg atcacgataa cccttactca aaaaatcctt ccc
//
LOCUS       DARYLD010000004        51653 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYLD010000004 DARYLD010000000
VERSION     DARYLD010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51653
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..237
                     /locus_tag="TU651_000197"
     CDS             <1..237
                     /locus_tag="TU651_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0896239.1"
                     /translation="YKKNSISKEEYLRKKILVQDRKKLLENKIKELENVEDDSKKELD
                     INNLDEDNLLKIYVDNIIDKIIASRTGEIEIIEK"
     gene            278..892
                     /locus_tag="TU651_000198"
                     /pseudo
     CDS             278..892
                     /locus_tag="TU651_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1422..2300
                     /gene="mvk"
                     /locus_tag="TU651_000199"
     CDS             1422..2300
                     /gene="mvk"
                     /locus_tag="TU651_000199"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL0896240.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2282..3226
                     /gene="mvaD"
                     /locus_tag="TU651_000200"
     CDS             2282..3226
                     /gene="mvaD"
                     /locus_tag="TU651_000200"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL0896241.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            3219..4217
                     /locus_tag="TU651_000201"
     CDS             3219..4217
                     /locus_tag="TU651_000201"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL0896242.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            4220..5212
                     /locus_tag="TU651_000202"
     CDS             4220..5212
                     /locus_tag="TU651_000202"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL0896243.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5497..6780)
                     /locus_tag="TU651_000203"
     CDS             complement(5497..6780)
                     /locus_tag="TU651_000203"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL0896244.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6767..7942)
                     /locus_tag="TU651_000204"
     CDS             complement(6767..7942)
                     /locus_tag="TU651_000204"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL0896245.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            8127..8966
                     /locus_tag="TU651_000205"
     CDS             8127..8966
                     /locus_tag="TU651_000205"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL0896246.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            9047..9544
                     /locus_tag="TU651_000206"
     CDS             9047..9544
                     /locus_tag="TU651_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL0896247.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9564..9734
                     /locus_tag="TU651_000207"
     CDS             9564..9734
                     /locus_tag="TU651_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896248.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9770..10999
                     /gene="clpX"
                     /locus_tag="TU651_000208"
     CDS             9770..10999
                     /gene="clpX"
                     /locus_tag="TU651_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL0896249.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            11009..11608
                     /locus_tag="TU651_000209"
     CDS             11009..11608
                     /locus_tag="TU651_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL0896250.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11972..14974
                     /locus_tag="TU651_000210"
     CDS             11972..14974
                     /locus_tag="TU651_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL0896251.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(15164..17257)
                     /locus_tag="TU651_000211"
     CDS             complement(15164..17257)
                     /locus_tag="TU651_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0896252.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17628..18047
                     /gene="ndk"
                     /locus_tag="TU651_000212"
     CDS             17628..18047
                     /gene="ndk"
                     /locus_tag="TU651_000212"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL0896253.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18548..19354
                     /locus_tag="TU651_000213"
     CDS             18548..19354
                     /locus_tag="TU651_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0896254.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19646..20611)
                     /locus_tag="TU651_000214"
     CDS             complement(19646..20611)
                     /locus_tag="TU651_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0896255.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20783..22066
                     /locus_tag="TU651_000215"
     CDS             20783..22066
                     /locus_tag="TU651_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL0896256.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            22068..22928
                     /locus_tag="TU651_000216"
     CDS             22068..22928
                     /locus_tag="TU651_000216"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL0896257.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            23093..24352
                     /locus_tag="TU651_000217"
     CDS             23093..24352
                     /locus_tag="TU651_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL0896258.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24352..24975
                     /gene="folE"
                     /locus_tag="TU651_000218"
     CDS             24352..24975
                     /gene="folE"
                     /locus_tag="TU651_000218"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL0896259.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24983..25783
                     /gene="folP"
                     /locus_tag="TU651_000219"
     CDS             24983..25783
                     /gene="folP"
                     /locus_tag="TU651_000219"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL0896260.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25790..26149
                     /gene="folB"
                     /locus_tag="TU651_000220"
     CDS             25790..26149
                     /gene="folB"
                     /locus_tag="TU651_000220"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL0896261.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            26146..26652
                     /gene="folK"
                     /locus_tag="TU651_000221"
     CDS             26146..26652
                     /gene="folK"
                     /locus_tag="TU651_000221"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL0896262.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26748..27635
                     /gene="murB"
                     /locus_tag="TU651_000222"
     CDS             26748..27635
                     /gene="murB"
                     /locus_tag="TU651_000222"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL0896263.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27681..28835
                     /locus_tag="TU651_000223"
     CDS             27681..28835
                     /locus_tag="TU651_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896264.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28819..29613
                     /locus_tag="TU651_000224"
     CDS             28819..29613
                     /locus_tag="TU651_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896265.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29610..30386
                     /locus_tag="TU651_000225"
     CDS             29610..30386
                     /locus_tag="TU651_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896266.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30379..31452
                     /locus_tag="TU651_000226"
     CDS             30379..31452
                     /locus_tag="TU651_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0896267.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31610..33142
                     /locus_tag="TU651_000227"
     CDS             31610..33142
                     /locus_tag="TU651_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL0896268.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33348..33962
                     /locus_tag="TU651_000228"
     CDS             33348..33962
                     /locus_tag="TU651_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL0896269.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34310..35437
                     /locus_tag="TU651_000229"
     CDS             34310..35437
                     /locus_tag="TU651_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL0896270.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35589..36266
                     /gene="radC"
                     /locus_tag="TU651_000230"
     CDS             35589..36266
                     /gene="radC"
                     /locus_tag="TU651_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL0896271.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36268..36963)
                     /locus_tag="TU651_000231"
     CDS             complement(36268..36963)
                     /locus_tag="TU651_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL0896272.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36975..37619)
                     /locus_tag="TU651_000232"
     CDS             complement(36975..37619)
                     /locus_tag="TU651_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL0896273.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37905..38252)
                     /locus_tag="TU651_000233"
     CDS             complement(37905..38252)
                     /locus_tag="TU651_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL0896274.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(38242..39369)
                     /locus_tag="TU651_000234"
     CDS             complement(38242..39369)
                     /locus_tag="TU651_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0896275.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39372..40346)
                     /locus_tag="TU651_000235"
     CDS             complement(39372..40346)
                     /locus_tag="TU651_000235"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0896276.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40481..41053)
                     /locus_tag="TU651_000236"
     CDS             complement(40481..41053)
                     /locus_tag="TU651_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL0896277.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            41148..41819
                     /locus_tag="TU651_000237"
     CDS             41148..41819
                     /locus_tag="TU651_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL0896278.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41794..42630
                     /locus_tag="TU651_000238"
     CDS             41794..42630
                     /locus_tag="TU651_000238"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL0896279.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42627..43529
                     /locus_tag="TU651_000239"
     CDS             42627..43529
                     /locus_tag="TU651_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0896280.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43533..44534
                     /gene="pta"
                     /locus_tag="TU651_000240"
     CDS             43533..44534
                     /gene="pta"
                     /locus_tag="TU651_000240"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL0896281.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44634..45392
                     /locus_tag="TU651_000241"
     CDS             44634..45392
                     /locus_tag="TU651_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0896282.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45497..46183)
                     /locus_tag="TU651_000242"
     CDS             complement(45497..46183)
                     /locus_tag="TU651_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL0896283.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46438..47166
                     /locus_tag="TU651_000243"
                     /pseudo
     CDS             46438..47166
                     /locus_tag="TU651_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            47159..48691
                     /locus_tag="TU651_000244"
                     /pseudo
     CDS             47159..48691
                     /locus_tag="TU651_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            49049..50032
                     /gene="guaC"
                     /locus_tag="TU651_000245"
     CDS             49049..50032
                     /gene="guaC"
                     /locus_tag="TU651_000245"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL0896284.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            50218..50799
                     /locus_tag="TU651_000246"
     CDS             50218..50799
                     /locus_tag="TU651_000246"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL0896285.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(51087..>51653)
                     /locus_tag="TU651_000247"
     CDS             complement(51087..>51653)
                     /locus_tag="TU651_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0896286.1"
                     /translation="LDQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAAL
                     INLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQI
                     KDKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPE
                     VEGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14626 a         9765 c        11832 g        15430 t
ORIGIN      
        1 tacaagaaaa atagtatttc aaaagaagaa tatttacgaa aaaaaattct tgttcaagac
       61 agaaagaagt tactggaaaa caagataaaa gaattagaaa atgtagaaga tgattccaag
      121 aaagaactgg atattaataa cttagatgaa gataatttgt tgaaaatata tgtagataat
      181 ataattgata aaataattgc atcaagaact ggagaaatag agattataga gaaatagata
      241 attcaggaaa ttctatatca attgcttgac attgtaggga aagtcctcta tcatgaattt
      301 gctgtatcgc ttttatgatg tacaatcagg cctcattaca gttgatgggc aaaatattca
      361 ggagtattct agagaaagcc tgcgttcaca gatgggtatt gtcttgcagg atccttattt
      421 gtttacagga acgattgctt ctaatatcac gatgggaaat ccagcttatt cggatcagga
      481 tattttagat gctttggaaa aggtcggagc ctcttcgatg attgctcgtc tggaaaaggg
      541 cattcatgag cctgtctatg aaaaaggctc ctcttattca agtggcgagc ggcagctaat
      601 tgcttttgct aggacattga ttgccgaccc taaaattttg atcttagatg aagcgacctc
      661 gcacattgat actgagacag aggacatcat tcaacaggct atggaggtct taaagaaagg
      721 ccgaacaacc tttatcattg cccatcgctt gtctaccatt caatctgcta atcaaatttt
      781 agtattggat aaggggagga tcgtcgaaag aggaacacat caggaattgc tagatcagca
      841 aggcatttat gctgaaatgt ccaagctaca agaaaaggtg gctgtacagt aatgcttttt
      901 agtgatagct atcaaaaaat tccttttcta ggccgtgtta agcagcagta gtctgtgaag
      961 taggagctat atttaggttt tgtgcctaag cctttaaggt ttttaagagg ctggattagg
     1021 gcttaacatc aataaaatca tatgtcactt tatcacagca tgttgtggtg aagtgttttt
     1081 tgtgtcgtcc tgctaaaggg aagatcctca cagtcagggc ttggctggct cctttatcag
     1141 agtcagatca ttcatacgta cttcctgtca ggcttggcta agttgaattg tatgttgaga
     1201 tcagcatgtc agcaatttat gctttgtgtc tgacttttag cagcttgtac atgaaatagg
     1261 actaaaggac acttgaattg atgaagaatc agcttaaaaa ccatttgtcc tagataggat
     1321 aagaactgtc taaaaggggg atagatcatc gcaattttta acaatttagt gtaaaatagt
     1381 aaggtgaatg ttttgatgaa ataaacgaaa agatttagga tatgaataag acaattggat
     1441 atggcaaggc acacagcaaa atcattttaa tgggtgagca ttctgtggtc tatggctacc
     1501 ctgcgttggc cttgccctta aaagatattg aagtgacctg ccggattttc cctgctgcaa
     1561 agcccttagc ctttgatttt tatgatccct tatcaacggc agtttatgca gccttggagc
     1621 atttggggtg cttggcagag cccattcatt atgatattat gtctcaggta ccacaaaagc
     1681 ggggcatggg ctcctcagca gctgtttcga ttgcagctgt tcgagctgtt ttttcttatt
     1741 ttgggcagcc cttgtcagat gagctgttgg aaatcttggt gaataaggca gaaatcattg
     1801 ctcacaccaa tcccagtggc ctagatgcta agacctgcct cagtgataag gccatcaaat
     1861 ttattagaaa tgttggtttt gataccattg atattcagtt aaatgcttat ttggtcattg
     1921 ctgatacagg gattcagggg catacgcgtg aggctgtcaa taaggtggct caatttgagg
     1981 aggaaaatct tcctcattta gccaagcttg gctgtttcac agaggctgtt gagcaagcaa
     2041 ttaagacaaa cgattgccta gctattggac gattcatgac gcaggcacat gaatcactaa
     2101 aggctattgg tgtcagtgtg gcaaaggctg atcagctggt tgcagcagct cttgaggctg
     2161 gcgctttagg agctaaaatg actggtggtg gcttaggagg atgtatgatt gcattagctg
     2221 aaaggataac agacgctcag caaatcagta agaaactaaa agaagaggga gctgtaaata
     2281 cgtggattca aatactgtaa cggtaacttc ctacgctaat attgctattg tcaaatactg
     2341 ggggaaaaaa gatgaggcta agatgatccc atcaacctct agtatttctt tgaccttgga
     2401 aggcatgtac acgacaacaa gtctttcttt tttgcctgcc tcagcaaagg gagatcagtt
     2461 ttatatcaat ggtgttctgc aggacgccaa ggagcatgct aagattactg cgattttgga
     2521 tcagttccgt cagaaggacc agacttttgt caaggttgaa gccagcaaca gcatgccaac
     2581 tgcggcaggc ttatcctcaa gctctagtgg cttatctgct ctggtaaagg cctgcaatca
     2641 gctttttcaa gctaagctaa gtcaagaaga gcttgcccaa aaggctaagt ttgcctctgg
     2701 ctctgcttcg cgttcttttt ttggccctgt tgctgcctgg gataaggata caggctctat
     2761 ttataaggtc aaaacagatt taaagctggc catgattatg ctggtcttga acgatgctag
     2821 aaagcccatt tcgagtcgag aggggatgaa gcgctgcagc acaacctcaa caagctttga
     2881 ccagtggctg gcccagtcag aaagtgatta tcaggccatg ttgcgtgccc ttagtgacaa
     2941 tgattttgaa acggttggtt ggctgacaga agcaaatgct ctagccatgc acgcaacgac
     3001 caaaacagcc agtccttcct tctcttacct aacagaggcc tcctatcagg ccatgctaag
     3061 ggtcaaagag cttcgtcaag agggctattc ttgctatttt acgatggacg ctggtccaaa
     3121 tgtcaaggtg ctttgtttag aagaggactt agagcggctg tcgcaccttt ttgaaaggga
     3181 gtatcgtatc atcgcctcaa aaacaaagga attaccagat gtctaaatat catgttcaag
     3241 caggaggaaa gctgtatctg acaggcgaat atgcgattct aaggccgggg caaacggcgt
     3301 tgatttgcta tattcccata atgctgacag ctgtcattga agcagcagag gctgttagta
     3361 tcagctcaga tatgtttgac catgctgctg atttgtcacc ggataaggat tataggctga
     3421 ttcaagcctc tattgaagcc tttagtttat atatagataa ggatattaag gagctgccag
     3481 ccttttcttt gtctattact ggtaagcttg agcgtgacgg taaaaagttt gggattggct
     3541 ctagcggtag tgttgttgta ctaacgctaa gagctttggc agccttttat caggttcagc
     3601 tgctaccaga gcagctcttt aagctggctg cttataccct gcttaaatca ggagataatg
     3661 gctccatggg ggacattgcc tgcattgcct atgagagctt ggttgcttat acatcctttg
     3721 ataggcgtaa ggttggtcaa tggttgatcg agatgaccct aaaagagcta atggcagcac
     3781 attgggggta tacgattgag actattgagc ctgctctgcc ctgttggttt cttgttggct
     3841 ggacccaagt cccttctatc tcaagagaga tgattcagct ggttaacaag agcattagct
     3901 gtcagttttt agagcaaagc cagctggtca cacaggaagt gatgactgcc ctgcagcttg
     3961 gtcaaagaaa aaggctcaaa gctagcattg aaaaagcggg tcagttgctg caagggttgg
     4021 cttcagttat ttatcaccct aagcttacgc agcttgtcca ggcttgtcaa gggcttgatg
     4081 ctgctgccaa atcatcaggc tcaggaggtg gggattgtgg tattgcactc gtttttgagg
     4141 ctaaggacat tgagcctatc cttgccagat ggcagcaagc agggattgta ttactatatc
     4201 aggaggaatg gggataaaca tgactaatcg taaggatgac catatcacac atgctttgag
     4261 ctatcattct ccttacaatg catttgacga catggagctc attcactgtt ccttgccgag
     4321 ctatgattta gctgatattg atctctcaac ccattttgct ggctgtgatt ttgagtttcc
     4381 tttttatatc aatgcgatga caggtggtag caagaaaggc caagcagtca atgaaaagct
     4441 ggccaaagtg gctgcggcta caggtatttt aatggtgaca ggctcttaca gtgcagcctt
     4501 gaaaaatcct gaggacactt cctttcaatt gcgaggtgta gcaccagatt tacagttggc
     4561 caccaacatt ggtcttgata aggctgttga cctagggatt agagctgtcg aggaaatgaa
     4621 gcccttgttt ttacaggtac atgtgaatgc catgcaggag ctgttaatgc cagagggaga
     4681 gcgcagcttt aagcattgga aggatcattt agcggcctat gccaagcagc ttccagtccc
     4741 tttgatttta aaagaggttg gctttggtat ggatattaag accatcacta tagcacgtga
     4801 tatgggagta aaaacctttg atatttcagg aagaggagga acctcctttg cctacatcga
     4861 aaatcaaaga ggaagtaatc gctcttacct agacgattgg ggacagacaa cagtgcaatg
     4921 tctattaaac gccaaaggtc tggttgatga agtggagatc ttagcctcag gtggtgtcag
     4981 acacccctta gatatggtta aatgcttggt gctgggggca cgtgctgtgg gcctatcgcg
     5041 agtggtattg gagttagttg agacctatcc agttgagcag atcatcgcta cgatcaatag
     5101 ctggaagaag gagcttaagc tcatcatgtg tgctttagat tgtcgaacct tgagcgattt
     5161 gcgtcaggtg gattatttat tatatggtag gctttatcag gcaaaccgct aaagactttt
     5221 tagccctgag ctaactttcc ttagaaaatc atcacaggag ttaagaagct gcctgcttgg
     5281 tgctgcaagc taattcagct gattatggct cgtaagattt ttagatgtct gaatgaaatg
     5341 ataggacaga tgacatagta tagcgctaat ttctagtgaa aatcagtcct tggtcaggtt
     5401 actgagactg aggttaagtt tatgtttaca ctaacactta aaggatatga aaacacttgg
     5461 tagctgccac tgaagctgtt accaagtgtt tttagtctat gattggctta atcgtatggc
     5521 tgttaagagc tgtcctgcct tttctaggtt cattggctta tcctttagta gagccttaac
     5581 tagttgaggc acctcctgct cactagcacc tgctaataga gctagagact tggcctgcag
     5641 cttcatgtga ccagcctgga taccagttga ggtcaaagcc tttagagccg caaaattttg
     5701 cgccagccca actgcagtgg tgatttgggc gagaacctta gcatttggtt gctctaaaag
     5761 gctatgagca acactgacgg ttgggttgag accgatcgac cctcctttac tagcaatggg
     5821 cattggcagt gttagctctc cgcataagct atttttagat aaatcaacgt gccagctact
     5881 tagccctcta taagagccag tccttgcggc ataggcatgt gctccagcct caatagctct
     5941 ccagtcattt ccggtagcta tagctaccgc atcgattcca ttaaagattc ccttattatg
     6001 cgttgctgct cggtaagggt caatctgggc taatttgctt gccagctcta tttttttggc
     6061 caattgctga gcttcttcct tatgtcgact taggtatctg aggtcaacct gacatttagc
     6121 actaactaaa gcttttgttg catagtttga gaggatagcc attaagcatt gaccaccgct
     6181 tagggcctcc aaatcaggta ctaaagcctc catcatcgtg ttaacgatgt tggctcccat
     6241 agcctcttgg gtatcaacgc tcagatagac aatgaaaaaa tcctccttac gctcaacggt
     6301 aaggctcttt gcgccaccac cacgcttaac aatagaaggg taggcattgt ttgcaacgtc
     6361 aatcaatgta tctgcgttag ctagaatagc cagcctagcc tgctcgtcat ctttaacatc
     6421 ataaagagct acctgcccaa gcatttgacg actgagtacc tcagtctgaa agccacctga
     6481 tcgcttgatg attttggcag caaaggaagc agcagcaaca acagaaggct cttcagtcac
     6541 aaaggggacc tgataggtat gcccattgat cagaaaatca ggggctagac taaaaggcag
     6601 agccagtcga ccgatgacat tttcggtcat ttgattggca atagcaatgg gtaagagctg
     6661 gtctgtctct aacagctttt gctgctgcgg gccaagcagc tggtcatctg cgagctgttg
     6721 aatgcgttct gcaaggcttt ttttataaaa gccggcccaa tttggtttag tttttgtcat
     6781 catcttgata aattcgttgg tgttccttaa tttctttgag ggcaaacctg ccagttagat
     6841 atggtgaaaa gctggcattg ccatcttggt ctagtctagg ctcttcataa aaaagtgctt
     6901 cataatcagc cactgaaatc acctgacgtt ggtctaatag ggcttgtcga ttagtcagta
     6961 gcatgtcctt gtaaccgtca acaagctgcc ctgaaaacag ctcactaaca gctcctgagc
     7021 catagctaaa caatccaatc ctatcaccag cccttagcac ctgactattc tctaaaagtg
     7081 ataataagcc gaggtagagt gagcctgtgt aaatgttgcc gatttgcttg ctgtaggcaa
     7141 tagaagcttg aaagttttca taaagccttt ctttgtgatc atctgctagt gattttgtca
     7201 tgatcttatg aagtcccttt agagcaagct ttggaaaggg gatatgaaaa caaacagcag
     7261 caaggtctga tagctcaata ccttcttttt cttggtattt gtcccaggtt gtttttaggg
     7321 aatcaaggta ttgcttggtc gaataaatac cattgacaaa tggtgttgag ctgtaatttg
     7381 gacgccaaaa atccatcaca tcacgtgtct gtgcgacatt gtcatgattt aactggagaa
     7441 tacgaggatt agtagtaact agcatagcaa tacttccagc accttgtgtt ggctctccgg
     7501 cggatccaat gccgtatttg gcgatgtcac tggcaatgac caagaccttg gaggctgggt
     7561 gtgcagcaac atgtaatttg gcataatcta aagcagcagt agcgctgtag caggcttcct
     7621 ttatctcaaa ggagcgtgca aagggctgaa tatcaagcag ctgatgaacg taaatactgg
     7681 ctgcctttga ttgatcaatg cttgattcgg ttgctaaaat gaccatgtca atgcttgctt
     7741 tatcgtcttt ggtaaggatt tggtcagcag ctgatgcagc aagcgttaca atatcctctg
     7801 taacaggtgc aatgcttaga gcgtcaagca ttagcccctg atgaaatttt gctggatcag
     7861 tgctgcgagc aagtgccagg tcttccattt ttaagacgta ttgactggtc gcaaagccaa
     7921 tcttatcaat tccgatgttc ataaatatcc ttcttttatc cattttatag tcctatccat
     7981 tttatcatat tttcttagaa aattagctga tttaatacga tagttttacc tttcaaacca
     8041 aaaacagcag catatagctt tcttctggta tttttgaagg aaattagata aaataatatg
     8101 gactgtgctt acagaaaggg gtttccatga caaaagcaga tcatattttt aaagctaata
     8161 tcaaaaaaat tatggaggag ggagtcttta gcgagcaggc tcgcccaagg tacaaaaatg
     8221 gtcaaacagc caattccaaa tacattacag gtgcttttgc agagtatgat ttgtctaagg
     8281 gagagtttcc tattacaact ctaagatcaa tccctatcaa gtcagctatt aaagagttat
     8341 tttggattta tcaggaccaa tcaaacagcc ttgatgtttt agaaaacaaa tacaacgttc
     8401 actattggaa tgagtgggag gtcggtcaga caagaaccat cggtcagcgc tacggtgcaa
     8461 tcgttaaaaa gcatgatatc atctcaaaaa tcctcaagca gctagaggac aacccttgga
     8521 atcgccgaaa tgtgatttct ctgtgggatt acgaagcctt tgaagaatca gaaggactgc
     8581 taccatgtgc ctttcaggtg atgtttgatg ttaggcgagt agatggtgag ctgtatttag
     8641 atgccacgct gacccagcgc tcaaatgata tgctagtggc tcatcatatc aatgccatgc
     8701 aatatgttgc cctgcagcta atgattgcca agcattttgg ctggaaggct ggtaagttct
     8761 tttattttgt caataatttg cacatctatg acaaccaatt tgcgcaagcc aaggagctat
     8821 tggagcgtca gccagcagcc tgtcagccca agcttttgct gcatgttcct gatgggacag
     8881 acttttttga tataagacca gaggattttg agctacagga ttattaccca gtgaagcctc
     8941 agctcacctt tgacttggcg atttaagcga aaaagacgat tttttctgag cattttgcca
     9001 agaaatttga tagaataaaa gaagttcata ttgaggaaag ctagtgatga caaagaagat
     9061 tattgctatt tgggcagagg atgaagcagg acttatcgga gcgtgtggca ggcttccttg
     9121 gtacctacca aaagagttgc agcatttcaa ggaaacaaca ttgaatcaag ctatcctgat
     9181 gggacgagta acctttgagg gcatgaaggg tcgtttgctg ccaaatcgcc aaacgcttgt
     9241 tatgaccaga gacagttatt atcatgtgga gggcgcttta accataacca gtgtgcagga
     9301 ggctttggat tggtatcatg cgcaggataa gaccttatat gtgattggtg gcagcaaggt
     9361 tttagaggcc tttgatggtt attttgatgt catcatcaaa acagtggtac atcaccagtt
     9421 tgagggtgat acctaccgac ctaggttaga gctgagtgat tttgtagagg agacctctgt
     9481 attgtaccca agggacgata acaatcctta cgatttcact gttacagtat tgagacatcg
     9541 ctaatatagg gagatgatag tctatgcagc gtagtatttt tggggtattt acggcctttt
     9601 tgtgtgcgat ttgtgtttta tgtgccatac cggcctttag aaaaaatcgc tatggcttag
     9661 gattactttt tttattaaat gcctttacta acctagtgaa taccatacat gccttttatg
     9721 gaacactgtt ttaagcctaa gagaatgaaa agagaaagat agaggaatca tggcaggaaa
     9781 tcgtagtaac gatattaagg ttcattgctc gttttgcggc aagagccaag acgaagtgaa
     9841 aaaaattatt gcaggtaata acgtctttat ttgtaacgaa tgtgttgcct tatcacaaga
     9901 aatcatcaag gaagaattgg cagaagaggt tctcgctgat ctgactgagg taccaaagcc
     9961 aaaagagctg cttgagattt taaatcaata cgtcattggg caggagcgtg ctaagagagc
    10021 cttatcagtt gcagtttaca accactacaa gaggatttca tttactgaga gtcgtgatga
    10081 tgatgatgtg gatttgcaga agtccaatat tctgatgatt ggaccaacag gctcaggaaa
    10141 gacctttttg gcacagaccc tggctaagag tctgaatgtt ccgtttgcta ttgctgatgc
    10201 aacctctttg actgaggcag gctatgtcgg agaagatgtg gaaaatatcc tcctgaaatt
    10261 aattcaagcc gctgattaca atgttgagcg tgcagagcgc ggcattattt atgttgacga
    10321 aattgataaa atcgctaaaa aaggtgagaa tgtctctatc actcgtgacg tatcaggaga
    10381 aggtgtccaa caagccttgc taaaaatcat tgaaggaacg gttgctagtg ttccaccgca
    10441 aggtggtcgt aagcacccaa accaagagat ggtacagatt gataccaaaa atatcttgtt
    10501 tatcgtcgga ggcgcctttg atggtatcga agaaattgtc aagcagcgct tgggagaaaa
    10561 gatcattggc tttgggcaaa atagtcgaaa gattgatgac aatgcttcct atatgcagga
    10621 gatcattgct gaggatattc aaaaatttgg tctgattccc gaatttattg gacgcttgcc
    10681 tgttgtggca gcgcttgagc agcttaatac tgaggatttg attcgtattt taacagagcc
    10741 tagaaatgcc cttgtgaagc aatatcaagc cttattgtca tatgatggcg tagagcttga
    10801 gtttgaaaag ggggctctgg aggctattgc aggtagggct attgagcgca agactggtgc
    10861 gcgtggtctg aggtctatta ttgaagaaac catgctggat atcatgtttg aggtgccaag
    10921 ccaagaggaa gtaatcaagg tacgcattac taaggaagct gtcgaaggtc aatcaaagcc
    10981 tattttagag atagcctaag gaggtatgat gtctgaagag caaatcctta acacgcataa
    11041 tgcttcgata ttgcttagtg cggcaaataa gtctcattac ccacaagacg accttcctga
    11101 gattgctttg gcaggtcggt caaatgttgg aaaatcaagc tttatcaata ctatactagg
    11161 acgtaaaagc cttgctagaa cctcaagcaa acctggtaaa actcagcttc ttaatttttt
    11221 taacgttgat gataagctaa ggcttgttga cgttcctggc tatggttatg ctaaggtatc
    11281 taaggcagag cgggctagat ggggaaagat gatcgaagag tacctgacca cacgacaaaa
    11341 tctcagagca gttgttagtc tggttgattt tcgccatgag tcatcacagg acgacattca
    11401 gatgtatgag tttttgaagt attatgagat tccggtgatt attgtggcta caaaggcaga
    11461 caaggttcct cgtggtcgct ggaataagca tgagtctatg gttaaaaagt ccttaaactt
    11521 tgatcaaaca gatgcgttta ttattttttc atctgttgag cgtatcggta ttgatgagtc
    11581 ttgggatacc attttagagt atttataagc atatggtaaa aaatttaagt atcttttaga
    11641 caggcacttg tgtctggtct gagaggtgct tttttattga caaaaaaaca atttgttgat
    11701 gacgagcttg tgttcaaaaa tgtcagtttg ctaaaaaatg atgataacaa acaagacttt
    11761 tatgatataa tgcttagcag gataatatgg agacatgaga aaaaggtcag agacagctaa
    11821 tttgctatcc ctgattataa ctatgatgac cagcattatt ataatactca tggtgctagc
    11881 tattagtagc agcacctaac ctatagtgtt gctttttagg ttacaagcac tggcgctagg
    11941 agtattataa tatatttaga aaggtttttt tatgacaata aaaaaatgcc ctcaaatact
    12001 tgccttattc cttgcttttg cagcgctagc tagtcagggg caaaccgtcc atgctctgga
    12061 gcggcaggag acatctgtca agcaagctca tgaatcagat gattggtttg atgaggacga
    12121 aggagttagc gatatcaagt ctaatacccc tacagagata gactcaacag taacagagtt
    12181 atttggtgat gctgagccta agactaaggc tgaaaaagaa gagtcaaaag ctccaagccc
    12241 taagcaagaa gcactgccag cagagtctca aaaagaaaaa gagacatctg ctaaatcgac
    12301 tgaccatgcg acagtacaag cagaagaggc acagcctgag caaggctcag atagtccttg
    12361 gctagcagat gactttgtta ctaagggaga taccttggtt gggctatcta aggcaggtct
    12421 tgctaagtta tcaaagacac ctgtcttggt actaccaagg atagggattg acaagacagt
    12481 gttgacaagg attgctagct ttgcctttac tccaaataaa tcagtcgcta ttgctgatta
    12541 tacaggtaga gcaggtgaac atggcgagat caatcatctg gacgtcgaag gcagagatat
    12601 ccttactgag ggagaggatt ttggtgccta tgcgattaaa aagcttgtga ttcctgaagg
    12661 ctatcttttt atcggtcaag atgcctttaa tgacaataaa cagctagaag aaatcagtct
    12721 acctgatagc ttactcagta tttcagacta tgcctttgct cacatgagtt tatctaagct
    12781 taagctgcca aaaagcctac agtccattgg agatcaagcc ttttttgata atcggattgc
    12841 aggcactttg gtattgccaa aagctctaaa gcagctggga gaacgcgtct ttaagtccaa
    12901 tcgcctcact ggacttgtct ttgagggaga aggcttgtct gtcctaaaag aagcagcctt
    12961 tcaagacaat gctttcatta gtcttgttat cccagatagc attcaagcct tagaagagga
    13021 cgtctttaca ggaaaccttg gcgatgaaga atacggtaat catgccgttt tacgaaccaa
    13081 aaatggtcag aatccttaca gacttcacag tgccaatgtt cttgtcaatc caagtgatca
    13141 ggctagaaca ccacagccac caattgatta caacaggtgg cttgcagaag attttaccta
    13201 tactggacag acgataaccg gtttttcagc tagtggactg cgcaaggtca aacgcaataa
    13261 gcatttggtt ctgcctaaga attatcaggg tcagcccttg acagccattg cagataatgc
    13321 ctttagaaat gtcaattttc atgataaaac cttgcgtaaa tacgacctag aaagcgtgac
    13381 gttaccatct accattcaaa agattggtgc ctttgccttt cagtcaaata atctagaaag
    13441 ctttgaggcc agcgaggact tggttgagat tggtcaagga gcctttatga ataatcgcat
    13501 tgagattctg gccttgaatg ataagctgaa ggtcattgga gatgcggcct ttcatatcaa
    13561 tcggatttat gctattgtta tccctgagtc ggtcgaagta attggcattt ctgcctttag
    13621 gcaaaatggt gctaaacatg tgatgtttat gggagataag ctaataagta ttggagaaat
    13681 ggcttttttg agcaatactc tggaggaagt ggatttgagc agcttagcag ggcttaagac
    13741 catcgctgtt caagcctttg cagacaatca cttgagagag cttaagctgc cagatagttt
    13801 gatgcgtatt gaagcagaag cttttaaaat taatagactt caaagagtga ccgttccaga
    13861 cactgtcatt agcattagct ttaatgcctt tgatcataat agtgatgaca aggttgtcct
    13921 aaggaccacc aatcacaata aaaacctgct agctgatgga aatggcttta ttgtggatcc
    13981 agacctatta agtgcggatc aatcgactgt tcaagcagtt ttagaggacc tgcggcgctt
    14041 agatctagct agtctacgtg ctgatacagc agctcatttt atgacactca tcacaagagg
    14101 taagcagcta ctaaaagaat ccgctgtacg gttaggttat cagcttaggt tccttgcaga
    14161 gtcacgattt ttcttagggc gcgtgagact ggatcagctg attaaaactg ctgacataac
    14221 cctatctagc catcaagaca cacctaatgc taagctgttg atggctaagc tagacaaggc
    14281 caagctgcat tacaataata gcgcaatgac tgctccaaaa gtaagtcgct tggaaaaaga
    14341 gctcagcctg ttaattgatc ttgtccaagg ggtaggcgct atctctaaag caacaatgac
    14401 tcaaggtgtc tataagcttc agacaaccct acctattcca gagtattata ttggggttaa
    14461 tctttatact gatgatcagg ggaatatttt atttgtgctt gacatgagtg atacgattgg
    14521 gcagggacaa cttgatgact atggcaatcc tattttaaat gttgatgagg ataatgaagg
    14581 ctaccatgct ttggccattg agtccttagc agattacgaa ggccttacga ttaaggatat
    14641 attgaccaag gagctaaatc aattgcctat tcgcgatgtc aagcaagcaa gagagcatcg
    14701 tgttggtctt tttatggcaa tcagagatgc tgcaagggaa gctcagcttc tactagaaaa
    14761 gcagagcaaa gccttatcag aatcagccgg caaatctaat ggctcaaaag tagctgactc
    14821 aggacttgag ccttctgtga cactatcaac caataagact aagctgctac caaaaacagg
    14881 agccttcaaa gaagcttggg tgacaatgat cggaatgctt gttcttttgg cggctaccct
    14941 acttaaaggc gatagtcgct acaaaaagaa gtaaataggc ttgcttagca agcacactct
    15001 agcaccagta aggcttgagg ggcttacaaa gcctatctaa tctagcaata gtatattgcc
    15061 agtgtgagct ggtgcttgag cttcaaaaaa acaaaagagc ctgaaatgac ttttactagc
    15121 atttcaggct ctttttagct tgtgattctt ttttgtgtga agcttacttc tcacttatcg
    15181 taatagtatc ttgatcaagg cttgctaata ggtgtttagc agtcgggtga tccaggtagt
    15241 aatccgtaat gcggtcacga atttcttgtt cgatgacacg tctaagtgga cgaactccca
    15301 tcgcatgatc atagcccaga tcaatcaaac gctctttaac atcgtcagtc acctcaaggc
    15361 taatgccttt tttagcaagg gtttggttca cttctgttag cattaaagca acaatttctt
    15421 gtaaatcctt tttcgctaaa tggttgaatt cgatgacacc gttgaagcga ttcaagaatt
    15481 ctggtctaaa gtaaggtgca atacgctcca tgatagcagg ctcttgatca gcacgatctc
    15541 ctgcttgatg gccaaaacca gcattagagg ttgcgatgat aaccgtattt ttgaaattga
    15601 tcgtgttgcc ttgtccatct gtcaatcgcc catcatcaag cacttgaaga agcagtgtaa
    15661 tgacctgtgg gtctgctttt tcgatttcat caagcaagat gatagagtaa ggactgcgac
    15721 ggacacgttc tgtaagggta ttttgattat catcatagcc aacatagcca gctgttgttc
    15781 cgattaattt ggaaacagct gtgcggtcac tatattcaga catatctaag cgaatgatag
    15841 cgtcctttga gccgaacata tcaagggcta actgcttagc cagctcggtc ttaccaacac
    15901 cagttggacc aacaaagagg aaggagccaa ttgggcgatt accgtcatca aagcctgcgc
    15961 ggttgcgtcg aatcgcacga gcaacagcct caactgcacc atcttgtccg ataacatggc
    16021 ctttaagacg gttactgatt tccttgagcc tttctaaatc actagccccc atatttgata
    16081 ctggaacacc agttagacgt tcaacagatt ctgcaatatc attaacagtg gcagtgacct
    16141 tttgcccttc actgtgatga ttgatttgct tttggagctc ctcaatgcgg gtcttagcag
    16201 ttaaggcctt ttcaaagtct tcttctgcaa cagccttttc ctgtagctcc ttttgcttag
    16261 tgatttctgc ttcaagtgat tttagatcag tgacagggtg ctgagctgct agatgagcag
    16321 cagtcatatc aacaaggtca atggctttat ctggtaggct tcgttgtgga atatattgga
    16381 tagcataatc aatagctgcc ttcaagacag agtctggtag gatcacattg tggtgctgct
    16441 cgtagaggtt gcgaatgccc attaaaatgt ggaaggtatc ctctgctgaa ggagcattaa
    16501 ccttaacctc gttgaaacga cgagcaagag cagcattttt tagaatggtg ttgcgatact
    16561 catcttgagt tgtggcacca atcagggtca actcaccgcg tgagagggct ggttttagaa
    16621 tatcagctaa gcccttagag cctgagtctg aaccagctga ccctgcacca aggatttgat
    16681 ggatttcgtc aaagaagaga atgatattgc cagcctcctt aacctcttta accatgtttt
    16741 gaatgttttc ttcaaaggag ccacgatact gtgtgccagc ctcaaggcca gaaatatcaa
    16801 ttgagataat ctctttattt ttgatggcag ctggcacatc accgttgaca atagcctggg
    16861 ctaggccttc gacaacagca gttttaccaa caccagcgtc accgacaaga acagggttat
    16921 tcttggttcg tcttgctaga atttctgcgg tcgcttgaat ctcatcgttt cgtccgatca
    16981 caggatctaa cctgccttgc cgagcttctt cggtcaggtt tgttccgagc ttggttagaa
    17041 tgccgtcttt tttaaggctg ctagcctgtt tttcttgtcc ctcagctgca gctagcttac
    17101 cggttttccg gtattcttga aattcctctg gtgtcatctc acgtccattg acaagatagc
    17161 gacgattttc gctgcggtag ccgccgatgt ttcccattaa ctgattgaaa atatcgtcca
    17221 tattttcaaa ggggtctttt ccataatagg ttgccatata cacttacctc acttgtatta
    17281 tatttaccag tcattatgag ctactggtat aggtagaagg tgatcggtgt tggctcatac
    17341 agagatcata gagaggtctt atgagagtct attgctcagg cttattactc accttctaat
    17401 aatattatat ccaaaaggtc agtaaaggtc aaacaaaaag tatgaataat taacctttat
    17461 aatcaggtgc ttatagccct tgaaacatca gatgactatg ccataagctg ctggtgcttt
    17521 tttgctagca aggctatctg taaagaagag acttttgtca aaaatggttt tactttttgt
    17581 tctaaaggct ttcatgatat aataaaagaa aagcacagag gtcaattatg gaacaaacat
    17641 tttttatggt gaagcctgat ggtgtgaaac gtggcttggt tggagagatt ctacgccgga
    17701 ttgagcgtcg tggctttacc tttgataggc ttgaattgcg acaagcaacc ccagaattgc
    17761 tagctaagca ttatgacacc ttaatcaata agccctttta tccagagcta gaggcctata
    17821 tgacaagcgg acctgtttta atcggcatta tctccggtaa tcgtgtggtc tcttcctggc
    17881 gaaccatgat gggggtaacc aatcctaaag acgctttacc ggggactatt cgtggtgatt
    17941 ttgctcaagc ccctggtgat gatggcggca ttttcaacgt ggtgcatggt tcggattcga
    18001 gagattcagc caagcgagaa attgcgatct ggtttggaca tagctgacat tgggcttggg
    18061 cctattcttt taagaactga taaagcaatt gcataaggag ttgataagcc catcatcaat
    18121 agtagctcag cattagaagg gtaacagcct tgatgttggg ctattttttt gcttgcctag
    18181 ggtctgtatg cttgtcctga tgagcaggta gacaaagcag cataagttta acaatccttt
    18241 gcggcagtga tcaattgtag ctctaaccat agcatcagct atttgaaagc cttgaaaaag
    18301 aaagctaagg ctaacaagct agtctaggtc atttactaca agcgactttt ttcaattagc
    18361 tgctcaaggc aagtattgaa aaaagtccat ttttcatgtc atttgtaata atatggtata
    18421 tttttaacga aaagtcgttt tagttgagaa aatatacaaa aaaggctatg atatagttaa
    18481 taaagttgtt ataccccctg tgtcttgtac actatgactt gtagagagtt tatcaaagga
    18541 ggataagatg aacaaacaaa gcatgaccca tttttctaag aagctgatga agttagccct
    18601 tttaggtttg gcattgccat taagcttggt gtcggtggta gatactccgg ttcttaacca
    18661 atccgaaaaa gctgtttatg ccaatgattt tggatctgga aatcgagcca gtgattatgt
    18721 accggcggct aacgcttgga gctttgaggc ttatccagat tactacagta ttttaggagc
    18781 tagtcatctt aatcctgctg tctttccaga gcctagtaag atgtcataca gtcctttaga
    18841 cgagttgggc cgcacacagg tcgcaagagg aacaataacc tatcacaata tcgtgatgaa
    18901 ttacaatgtt cggcaacgct ttgctaaaaa tcagaaccct tcaggctgga ttggtaaccc
    18961 tagaaatgtt cgctacacta ttgagtggct agatggacta tcctatcagg gagatttttg
    19021 gaatcggagt catttgattg cagatagcct tggtggagca gccttacgtg tcaatgctat
    19081 tactggtaca agaacacaaa atgttggcgg cagaaatcaa agaggcggta tgcgctatat
    19141 tgagcaaaag gtgcagcagt ggattgagca gcatacaagc gcagttgttt attacgaagc
    19201 ggtgccaatt taccaggcaa atgagctagt tccaagagct gttgttgttt cagcattgtc
    19261 atcagacgga ggtcttgacg aaaaggtcat ggtctataat accgccaacg gctataccat
    19321 tgattatgcc actggcgcat tccgcagtaa ctaggctttt gtactaagct gtagctgatc
    19381 aaggtctgac taagacaagc tcatcagcaa ttggtatata aaaagacgtg gcaacaacat
    19441 gttttaaatg agttgtcatg tctttttagt gtcgtcagct tttcacattg tcttagaatg
    19501 atcacaccta gctagccgct aaaagcattg gtccaaagaa atgttaagaa tagatagaat
    19561 gccttttaat cagtggtatg ggactgctag ctaatataat gcctgcagtt gagccaattt
    19621 ctcatctagg ctaataacta acaagctatt gacttatcgt gttcattaga atgtcagctg
    19681 ttgtagttgg tagtattcga atacgattaa gcgatagcag gccattagca gcacttgcta
    19741 gtccttcatt tgttgtgacc cctaatttgt aatgcagatc ctcagcaatc tttaatgtgg
    19801 tatcagtata acgacctgct ggataggcaa ttgcaatggt atcttggtgt agctctctat
    19861 ctaggtattc tttagaatct ttcatttcag cggtttgact agcagcgctt gcctgagata
    19921 gatcagggtg gttaaccgta tgatcttgga aagacatgcc tgcctgcttc atttccttca
    19981 tctgatccaa tgtaagattg gccgcattac ctgcctctgt aaagccagtg ataacgttat
    20041 tggtggcctt gatgtcatac tttttcagga ttggaaaagc aacgttgtaa aaatcaacca
    20101 tgctatcatc aaaggttagc cagacaacct tttcagcagg aagctcgtta gctgataaga
    20161 ctcggtaggc ttcttcggga gataaaaagt agtagccggc ctccttcatt gcctttagct
    20221 ggctttcaaa aagatctgga gcaacgatga gattggcact tgctgcctct tctggtgcca
    20281 taacgtgaat agcatgatac attaagatag gaagcttaac agggttttgc tgcttggtcc
    20341 agctgacagc tcctttttgc tgctgactat ttgtatggct agcttcctta ttagttgctt
    20401 ttttgctagg cttgggagct ggttttttat cagtttttga aaataggctt attttgggga
    20461 ttgcctgcga taattgagag atgcttatct ttgaatggct cttgtaaagg tagacaatag
    20521 ctgataagcc tatgatacag gcaagtagta gcatgagatt aatcattttg aagatttttc
    20581 ttttcttacg ccgtttgttt ctgttgttca tcacttgctc cttgtttatt gattagtcta
    20641 ttgtaacatt tttttaagta agctgtcttt cgttaactta attttttgct aacattctat
    20701 tagtgttatg ctttgtaaaa caagacctag atttgctata ataagacaga gtatttaaga
    20761 cagtcaaaaa aaggaggata ggatgtcagt taaggttgca ttattaggct ttgggactgt
    20821 tgctagtggc attcccttgc tattagaaaa caatagtagc aagattcgtg cagtggtagg
    20881 tgatgatttg gtgattgcaa aggttctggt tagagatgag accactaaga agcgtttgtt
    20941 ggatcaaggc tattcctacc aatttgtgac ctccattgat gatattgttg atgatgagag
    21001 cattgatatg gtggtcgaat taatgggtcg tatcgagcct gcaaagacct ttatctcgcg
    21061 tgctctatca gccggaaagc ctgttgtgac tgctaataag gatttgatag ccttgtacgg
    21121 aggagagctc tcgactttgg cagctaagca tcaggtagct ttgtactacg aggctgctgt
    21181 tgctggtggt attccaatac taagagcttt ggctgattcc tttgcctcag ataagctgac
    21241 gcgtctgctc ggtgtgctca atggaacaac taatttcatg ttaaccaaga tgattgatga
    21301 gggctggacc tatgaaaggg ccctgcaaaa agcgcaggag ctgggctatg ctgaaagtga
    21361 tccgactaat gatgtgaaag ggatcgatgc agcttacaag gttgctattc ttagtcagtt
    21421 tgcttttgga atgaccattg actttgaggc tattagctat tcagggattg ataaggttcg
    21481 agtagaagat gtgacagtag cgcagaagct gggctatgtg atcaaattag ttggtctact
    21541 tgaagagacg gcttctgggc ttaacgcaga ggtatcccca gtctttttac caaagacaca
    21601 cccgttggct gctgtagacg gtgtgatgaa tgctgtttat atcgagtcaa ttggggttgg
    21661 gcaggctatg ttttatggtc caggtgccgg tcaaatgcca acagctacag ctgttgtggc
    21721 agatatgatt cagactgcct gcaccttacg tgaccataca gtctcagtct ttaatcgttt
    21781 tgctacaaaa actagactag ctaagtctga ggatattatg agtccctatt actttgctat
    21841 tcaagcaact aataagtttg gtcagctact agagctaaca aggctatgtg atgtttgtgg
    21901 cattagagtt gagcagctgt tatcagatga gatagatagt gacaggttag actttgtgat
    21961 gattactcat gagatgagca aaaaggagct tgcttgcttt acagcgctac tacaggatca
    22021 tcaggatttc cgtatgttaa gtacatttaa gattttagga gattgacatg aagatacgcg
    22081 tacctgcaac ctcggctaat ttgggacctg gatttgactc aatggggatt gctgtttcaa
    22141 aatacctaga agttgacatt ttagaagaac gtgaccaatg gtttattgag catgatttgg
    22201 gtgatattcc aaatgatgat agcaacttac ttatccaaac agcccttagg ctagcaccaa
    22261 atattccagc acatcgtcta aagatgacgt ctgatattcc attggcacgt ggcttgggat
    22321 cgtcctcctc ggtgattgtc gctggtattg aattagctaa tcagctaggg catttaaacc
    22381 taacagacga ccgtaaattg gccatagcaa ctcgtattga ggggcaccct gataatgtag
    22441 ctccagcgat ttttggtcaa ttggtaattg cttcacagat tggtaaggac gtggattaca
    22501 tcattgcgcc ttttcctgac ctttctttgg tttgttttat tcctgattat gagctgaaaa
    22561 cctctgattc cagagatgta ttgcccaagc agctatcgta taagcaggca gtggctgctt
    22621 cctcagttgc taatcttgct atagctgcgc tattgaccgg taatttgaaa aaggccggtc
    22681 gggcgattga aaatgaccaa ttccacgaaa tctaccggca aagattagtc agagagttcc
    22741 agccgattaa gcgagctgca gcagctaatg gtgcttatgc aacctactta tccggtgcag
    22801 ggcctgctat tatggttatg tgtcccaata agaaaaaaat ggcgatttat gaggccatcg
    22861 agcagctagg tctaattggt cagttggtgt ctctagagct ggatcgtcag gggctgtgtc
    22921 ttgtctagac tggcaaggta ctggtatgct tgcctagtag gcttattgtt gatatcagat
    22981 ggacttaaag cttagtcatt caaatacatc aaaaaagtga ggcttgatcg ttttatcggc
    23041 tttcactttt ttcttgatat gttatactag agtagacttt gtgaggtgtg tgatgaatta
    23101 tcaagaaaca ttagactgga ttcatggtca ggaaagattt gggatcaagc caggtgtaaa
    23161 acgcatgcgt tgggtgcttg agcagctagg taatcctcaa gataggatta gaggaatcca
    23221 tgtggtcggc acaaatggta agggatcgac ggtcaatgac ctacagcata tttttactag
    23281 agcaggctat gaggttggaa cctttacctc gccttatatc atggatttta aggaacgtat
    23341 ctgtctcaat ggtgagatga tctcagagac tgaccttgtt aaggctgcta attgtattcg
    23401 tccactaacg gatcgcctta tcagtgagac aagtttgggt cctgcaacag tctttgagct
    23461 gatcactctg atcatgtttc tttattttgg tgagagtcac ccggttgata ttgctattat
    23521 cgaggcagga ttaggggggc tttatgactc cactaatgtg tttcaggcga tggctgtggt
    23581 ttgcccgtct attggtcttg atcatcaagc tattttaggt gatacctatg ctgacattgc
    23641 ctatcaaaaa gccggtgtgc taaagggtgg tgaagacctt atttttgcca ttgataacaa
    23701 agaggccaga caggtttttc taaaaaaagc agagcagctt ggcgtgccta tttgggaatg
    23761 gcgtcgacag ttcaacatgc tacagggtga aggtggttat caatttaaca gtcagcttgg
    23821 tcagctgtct catctagtgc ttgcaatgcc tggtcagcat caggtagcca atgcaggcct
    23881 agccactatg acaagcttga tattacagga tcggtaccca aaggtaactg agtctgttat
    23941 tagagaggct ctggcaagca gcttttggtt gggacgaaca gaattgttgg cacccaacct
    24001 gatgattgat ggtgctcata ataatgaaag cattgccgcc ctgattgatg tgatatcatc
    24061 agactatcag gataagcaga ttcatattct atttggtgcc attgatacca agcctgtctc
    24121 agatatgctg cagagtctgg agcgtcttgg agatgtgcaa gtaacaagct ttcactatcc
    24181 caatgcctat cctttggagg cttatccaga taggctaaca aaagtagcag attttagagc
    24241 atttttagac cggcttgagc aagcagctgc tgatgatttt ttcctgatta caggctctct
    24301 ttacttcatc tcagaggtca ggcagtattg gaaaaaggta ttaagcaagt aatgctttct
    24361 cacatcaact catcaaacaa gattaatcaa ctaaaaaggg gaaaaccatt gccaatcaat
    24421 caaaaaaaag cagaagccgc tatctatcaa ttattagaag ctatcggtga ggatccaaac
    24481 cgagaagggc tacgagatac cccaaagcgt gttgccaaga tgtatctaga aatgctctca
    24541 gggctggaac aggacgctaa ggatgaattt acagctgttt ttacagagca tcacgacgat
    24601 ttggtgattg ttaaggatat tagcttttat tccatgtgtg agcaccatct ggtgccattt
    24661 tatggtaagg cgcatattgc ttatttgcct agtgatgggc gtgtgacagg cttgagtaag
    24721 ctggcaaggg cagttgaggt gacgagcaaa agacctcagc tgcaggagcg tttgacagct
    24781 cagattgcta atgctcttgt tgatgccttg cagcccaaag gggtttttgt tatggtagaa
    24841 gcagagcata tgtgcatgac catgcgaggt gtcaaaaagc caggcagtaa gaccattacg
    24901 acaactgcta gagggattta caaggatagt agagacgaca ggcgtgaggt tatgcaatta
    24961 atcatggagg gctagggtat ttatgactat tggacattat tcagccgctg gtgaggcagc
    25021 tattatgggg attttaaatg tgactccgga ttcgttttca gatggtggct cctatactag
    25081 tgttaatcag gccttggcac aggccgaaaa aatgctgtca gaaggagcga ctgtcattga
    25141 tattggaggc gagtcaacac gaccgggctg ccaatttgtg ccggcagaag aagagattgc
    25201 acgcgttgtt ccaatcataa aggccattaa aaaacggtat gatgtcctta ttagcattga
    25261 tacctacaag acagaaactg ctagagcggc ccttgaagca ggagcagata tgctcaatga
    25321 tgtctgggca ggactatatg acggtcaaat gctaagtcta gccgccgaat acgacgttcc
    25381 cattatatta atgcataatc aaaccaaaga ggcttatgct gatgttacaa aagaggtttg
    25441 cagcttttta caggctagag cagctgcagc cctcaaagca ggtgtcaaaa aagaacatat
    25501 ctggcttgat ccaggatttg gctttgctaa aaatgttgag caaaatatag ccttattaaa
    25561 agggctaaat gaggtttgcc agttgggcta tcctgttctt tttgggattt ccagaaagcg
    25621 tgttgtagac gccctacttg gtggcggcac taaagccaag gatcgtgacg gggctactgc
    25681 cgccctatca gcctacgcta ttaataaggg gtgtcaaatg gtgcgcgtgc ataatgtcgg
    25741 tgctaacagg gatattgtct ctgtattgag tcaattaagg tgagaaatga tggataaaat
    25801 cagattagag gcttgtcgct tttatggtta tcatggtgcc tttaaggagg agcaggtctt
    25861 aggtcaaatt tttgtagtgg atttagaatt atcagttgac ttgatggctg cctctctttc
    25921 agactgccta gaggatactg ttcattatgg tttagttttt gaaacagtcc gtcaaattgt
    25981 tgaggaaaag acctttacgc ttatcgaacg tttggctggt gccatttgtc aagagctatt
    26041 tgcccagttt ttgcctatta aagcgattaa aatcgctatt aaaaaagaaa atccaccgat
    26101 tgcaggccat tatcaagctg tcggtattga attggagaga aagagatgac acttgtttat
    26161 ttaggcttgg gaactaatat gggagatagg gcaggctacc tacaggcagc agttaatgcc
    26221 ctatctaagc tgccagagac tgagttactg agacaatcct ctatctatca aacagcagcc
    26281 tggggaaaaa cagatcaaaa tgcctttttg aatatggctt gccagctaga tactaggctg
    26341 acatcagaag ctcttttggc agctacgcag gctatcgagc aggctctggg acgagttcgt
    26401 catgaaaaat ggggcccaag gacaattgat attgacctct tgctgtttgg tgatgagccg
    26461 tatcaatcag agaccttggt tattcctcac ccttacatga cacaaagagc ctttgttttg
    26521 attcctttat tagagattgc acccgatgtg accttacctg gtagccagaa aagcctgagg
    26581 tcttaccttg atgctttaga gcaatcagat gtagccttgt ggtcacatga gtattcaaat
    26641 aagttttctt aaactgtcgt tatttttact aaaatttgat ataatagtgc tactctttgc
    26701 tgattttttg tcttatatta agaaatgatt gaagaaagaa gaagattatg atagctgaac
    26761 ttgaaggcat tgatattcga gagaatgaag ccttaaaaca ttacacctat acccaagtag
    26821 gcggtccagc agatttcttg gcttttccta gaaatcatta cgaactatcc cgtattgttg
    26881 attatgccaa tcataatcat attccttgga tggtccttgg aaatgccagt aatctcattg
    26941 ttcgagacgg tggtattcgt ggctttgtta tcatgtttga taagctcaac gccgtccgcc
    27001 ttaatggtta taccttggag gcagaggcag gcgctaacct cattgaaaca acaaaagttg
    27061 ccaaatttca tagcttaaca ggctttgaat ttgcttgtgg cattcctgga agcatagggg
    27121 gtgctgtttt tatgaatgca ggtgcttatg gtggagagat tgctcatatt tttttgtcgg
    27181 ccaaggtctt gacaccagaa gggaaaataa aaaagatctc agccagagag atggcctttg
    27241 gctatcgtca ctctgtcatt caagaaactg gtgatattgt gatttcagcc aagtttgctt
    27301 taaaaccggg taatcatgac agtatttgtc aggagatgaa tcgcctcaac caccttcgaa
    27361 agctcaagca gcccttagaa tttccctctt gtgggtccgt ttttaagcgt cctcctgggc
    27421 attttgcagg gcaattgatt atggacgcta acctaaaagg gcatcgtgtt ggcggtgttg
    27481 aggtctctaa aaagcatgca ggctttatga ttaatgttgc tgatggctct gccaaggatt
    27541 atgaggactt aattgctcat gtcattagga cagttgagca ggcatctggc gttaggcttg
    27601 agccggaggt tcgtattatt ggtgaaagcc tttaatgatt gtgttatcaa aaaagaaaaa
    27661 ttgtggagga tttatgacaa ttgactaagc caattatcac atttgacaat gtctcaaaga
    27721 catttgagga cagcgggaca caggtcctaa agaacattaa ttttgagctt gaggagggaa
    27781 aattttacac cctgcttggt gcctcaggat ctgggaaatc aaccatttta aatattatgg
    27841 ctgggctgct tgatgcgacc agtggtgata tttatttaga tggtgagcgt atcaatgatt
    27901 tgccgaccaa taagcgtgat attcacactg tttttcagaa ttatgctttg tttcctcata
    27961 tgacggtttt tgagaacgtt gcctttgctt taaagctgaa aaaggttgac aaacaggaga
    28021 tagcaagacg tgtcaaggaa accttaaaaa tggttcagct ggagggctac gaaaagcgat
    28081 ccattcaaaa gctttccggt ggtcagcgtc agcgtgtagc gattgctcgt gcgattatca
    28141 atcagcctcg tcttgtccta ttagatgagc cactttctgc ccttgatttg aaattgagaa
    28201 cagaaatgca gtatgagctg cgtgagctgc agcagcgact gggcattacc tttgtttttg
    28261 ttacccatga tcaggaagaa gcactagcga tgagtgattg gatttttgtc atgaatgatg
    28321 gtgaaattgt gcaatcaggc acacctgtag atatttacga tgagccgatt aatcattttg
    28381 tagctagctt tattggtgaa tcaaacatca tcaatggtac gatgattaaa gactatctgg
    28441 tttcctttaa cgggaaagaa tttgagtcag ttgatggtgg tatgcgaccc aatgagccag
    28501 ttgaggtggt tattcgaccg gaggatttac aaatcaccct gccagaggaa ggaaagcttc
    28561 aggtaaaggt agatacacag ctctttcgtg gtgttcacta tgaaatcatt gcctatgatg
    28621 atttaggcaa cgaatggatg attcactcaa cccgcaaggc cattgaagga gaagtgattg
    28681 gtttagattt cacaccagag gatattcata ttatgcgcct caatgaaaca gaagaagaat
    28741 ttgatgctcg tatcgaagaa tacgttgaaa tcgatgagca tgcggatggc ttaatcaatg
    28801 ctattgagga ggagcgcaat gaagaaaacc tctagcctct ttgcagttcc ctatttttta
    28861 tggattgtcc tctttgttat ggcaccggtt gcccttttgc tttatcaatc cttttttgac
    28921 atcgaaggac gattgacact agccaattac gagacttttt ttagctcatg gacttacctg
    28981 agaatgggct taaactctat cttatatgct ggtatcgtta ccttggtgac ctttttgatt
    29041 tcatatccca cagctttatt gttaacgcgt ttaaagcaca agcagctgtg gttaatgctt
    29101 attattttac caacctgggt caatctgctc ctcaaggctt atgcttttat ggggattttt
    29161 gggcagcagg gtggtatcaa tagcttttta acctttatgg gcttaggacc acagcaaatt
    29221 ctgtttactg atttttcgtt tatttttgtg gcctcttata ttgagctgcc ctttatgatt
    29281 ttgcctattt ttaatgcttt agatgatatt gatgataata ttatcaatgc cagtaaggac
    29341 ctgggtgcca atgactacca gaccttttca agggttatct ttcctttgtc gctaaacggt
    29401 gttagagcag gggttcagtc tgtttttatt cccagcttga gtctctttat gcttacgcgt
    29461 ctcatcggtg gaaatcgtgt gattacgctg gggacagcta ttgaacagca tttcctaaca
    29521 acagaaaact ggggcatggg ctcaaccata ggtgttgtcc taattatcgc gatgattgtg
    29581 attatgtggc taacaaagga gaaaagtaaa tgaaaaaatt tgccaatctt tacttagcgt
    29641 gtgtttttat tttgctctat attccaatct tttacttgat tgtttattct tttaacaagg
    29701 gtggagacat gaatggcttt tctggcttga cgctagagca ttataagacc atgtttgatg
    29761 atagtcgctt gatggcgatt ttattgcaga cctttgtgtt agcctttaca agtgccttgc
    29821 ttgcaaccat tatcgggacc tttggggcga tttttattca tcagagtaaa aagaagtacc
    29881 aaaatgcgat actgtctgca aataatgtgt tgatggtttc ccctgatgtg atgataggtg
    29941 cctctttctt gattctcttt acgtccttga aatttcaatt aggaatcctc tcggttttga
    30001 tgagtcatat tgctttttcc attccgattg tggtcttaat ggtgcttcct cggttgaagg
    30061 aaatgaatca agatatgatt aatgcagctt atgatctagg agcaaatcac tttcaaatgc
    30121 taaaggaggt tatgcttcct tatctgacac cgggcattat cgcaggctac tttatggcct
    30181 ttacttattc cttagatgat tttgcggtga ccttttttct aacaggaaat ggctttacaa
    30241 ccctgtctgt tgagatctat tcgcgtgctc gaaggggtat ttcattagat atcaatgcct
    30301 tatcaacgat tgtctttttg ttctcaattc tattagtcat tggctattat tacatttcac
    30361 aggacaagga ggaaaagcat gcgtaagcta tactcttttt tagcgggaat tatcggggtt
    30421 atcttgctgc ttgcgaccct gtcctttatt ttgcagaaaa aaacgagctc tgctagtcaa
    30481 tctgataagc tggtgattta taactggggt gattacattg atcccgcttt gctgaaaaaa
    30541 ttcactaagg aaaccggtat cgaggttcag tatgagacct ttgattccaa tgaagccatg
    30601 tacaccaaga tcaaacaggg tggaacgacc tatgacattg ctgttccgag tgattacacg
    30661 attgacaaga tgattaagga aaagcttctt gttaagctag ataagtccaa gcttgttggt
    30721 ctagataaca ttggtcagga gtttttagga aaaagctttg atccgcacaa tgattattcc
    30781 attccttatt tttggggaac ggtaggcatt gtctataatg accagctggt ggataaggct
    30841 cctatgcatt gggaggattt atggcggcca gaataccaaa atagtatcat gctagttgat
    30901 ggtgctcgtg agattttagg tgttggattg accacatttg gctatagcgt taactcaaag
    30961 cacctaaagc agcttgaagc agctgaaaaa aaactacagg ccttaacccc taatgtaaaa
    31021 gcaatcgtcg ctgacgagat gaaggggtat atgattcagg gtgacgctgc tattggtgtt
    31081 accttctcag gagaggctag cgaaatgctg gacaataacg accatctaca ctatgttgta
    31141 ccatcagagg gctcaaacct ttggtttgat aatctggtgc ttcccaaaac aatgaagcat
    31201 gaaaatgaag cctatgcctt tatcaacttt atcatgaagc cggaaaatgc agcacaaaat
    31261 gctgaatata tcggctatgc cactcccaat acaaaagcga aggctttatt gccagatgat
    31321 attaaaaatg acccagcctt ttacccaact gacgagaccg taaagaaatt agaggtttat
    31381 gataatttag gctctaaatg gcttggtatt tacaacgacc tttacctaca atttaagatg
    31441 tatcgaaaat aggtcatgca agattgaagg agctattcat tggaaagctt cttcagtctt
    31501 ttttagcttg gtctggtctc aataatctca tgagattaaa aagaactaga atcttgcttt
    31561 cgtctttgat acaatagtag tggtttatta aaatgaaaga gatgacaaaa tggaaaatca
    31621 taaaaacgag tttacctttt ccaaacattc aatcatagcc tacgtttggc gtggcatttt
    31681 agtcgggata attgctggag ctattgtcag tttgtttcgc ttattgattg agatggttag
    31741 tgaggctgtt gttggctatt atcaccaagc tcacagcaat cgcatgctcc ttgttccgat
    31801 agcaggcttt agcttattag ctgttttttt agttggtctt ttggtcaagt ctgacgccaa
    31861 cattaaaggc tctggtattc cacacgtcga aggggagcta aagggcttga tgtcacccaa
    31921 ttggtggagt gtgctttgga aaaaatacct tggtggaaca attgccattt ctatgggctt
    31981 aatgcttgga agagaaggcc cttctataca attaggggct atgtcagcta aaggcttagc
    32041 taagtacctg aaatctagtc gtctagaaaa acgtgtcttg atcgctagtg gagcagctgc
    32101 tggcttatca gctgctttta atgcgcctat tgcaggactg ctttttgttg ttgaggagat
    32161 ttaccaccat ttttcaagat tagtgtggat cactgccttg gttgcaagcc ttgttgcgaa
    32221 ctttatttcg ttgaatattt ttggccttag acctgttttg gccatgccta aggccatgcc
    32281 ctttcttgcc ttacatcaat attggctgct cttaatctta ggccttgtgc ttggctgtct
    32341 gggctttctt tatgaagagg tcattttaca ttttcatagg gtttatgatt ttcttggaaa
    32401 gagcttgcgc ctagcgccgc attttcatgg gctgattgtt gttgctatta tcctgctgat
    32461 tggctattat ttgccacagc tattgggcgg aggtcatggt ttgattatgt ccttgtcaga
    32521 gcaaaagcta ccactgttga ctgttcttgc ttacttcttt attcgatttt tagggagtat
    32581 gtttagctat ggcagtggcc tgcctggagg aatttttttg cctattctaa ccttaggtgc
    32641 cttgtccgga actatttttg gattgattct tcagcaaata ggactgttag atcgccagat
    32701 gattcctctc tttttagtat tgggaatggc aggctacttt gctgctgtat caaaggcacc
    32761 cttgacagga atgatcttag tgactgaaat ggtaggggat ctgaagccct taatggccat
    32821 tgctgttgtg accttcgtgg cctacttggt gatggatttg ttaaatggtc agcctatcta
    32881 tgaagcaatg ctagagaaaa tggctatcaa acacccaaca gatctagtgg agccgaccct
    32941 gatcgaatta cctgtaagtg agaaaattgc aggcagatat gtccgagacc tgaagctacc
    33001 taaaaacgtt ttaattacaa cgcagctcca ccataagaaa tcacaggtcg tctcaggtga
    33061 tacgctattg atttcaggtg ctacgatctt tttggtggtc aatgaagctg atacaggctt
    33121 tgttcgagag gtcttgatgt agagcaaggt cggttaagca gtcagcagta gctgtgctac
    33181 cgatcaaaga agcagatcag tgctttttct catctgatga aaggtattga tttgcttttt
    33241 ttgtgttatt aaacctttgt tagcaagagc catagcctta gcagtcgtat ctgatgaata
    33301 cctgctgtct ttttgttata cttaagtatc aatcaaagga gctttatatg ctagaagtta
    33361 tttcaaaaga gctgcgccat taccaaaaga ataagcttgc cgcctatcaa aaaaagaacc
    33421 aaggcataga agctggtgga attgtttttg ctggcgattc gttaatcgaa tttttcccgt
    33481 tgaaaaaata tttcaaacag gtctcaacca tttataatcg cggaattgca gggatagaca
    33541 gtcagtggtt gctagagcat attgacagtc atgtgaatga tctggagccc agtcatgtgt
    33601 ttatcctgat tggctgtaat gatattgggc ttggctttga tcaatcgcat atcgtatcga
    33661 ccattgttga tcttattagt cgtattcgca gtcagtctat ttatactagg attagccttc
    33721 tgtccttatt gccggtttct gaaaatcccg cctatcaggc gactgtcaag ctaaggacaa
    33781 atagggctat tgatgagatt aatcaagcat tagcaatgat accagcgatt gaatttattg
    33841 atcttaacgc ctgcttaaag gacgagactg gtggcttagc agctgcttat acggtagatg
    33901 gcattcatct taatgccctt ggctatgaac acttagctca agctattagt ccctatctat
    33961 gaaaggtaaa ggctggagct gctaatttgt aagggatctt taaaaaacaa gcactgatga
    34021 atcatcattg aaacccttca gagtgccgat aggctgcaca atcaaagaag cattaggttt
    34081 gtctatgacg cccttgtgtt aagctggctt ttaggtttat actgcgagaa aatcagtcat
    34141 tgggctggga gtctcaaagc ttagctgtgg taattaaatg cgagctcctg ctagcttgtg
    34201 ctgatcaagc agtatagcaa ggagggactg aacttttagt ctcagataat attagacttt
    34261 ttatcctata ttaaacgatt tagtgtataa taaacaggaa ggagttaaaa tgaaatttga
    34321 aaaaaaacaa gtcttttatg ttgtgcttgc ctttgtgctt tgttatgcta ttcaagctaa
    34381 ttgggataat ggggctaata ttgtcacaac cgtttataag acaagcctgc cctttcttta
    34441 tggagcagca gtcgcctata ttgttaatat tgtcatgagt gcctatgaaa gagcttatac
    34501 ttatacccta aaaccctttc cttttgccat gaaggctaga agagggctct gtatgctttt
    34561 ggcatatttt acctttatca gcttgatcgt atggattatt tctattgtaa tccctgattt
    34621 gattgcaagc attagctcgt taacgcaatt tgatacaaga gctatcaagg aggtcatcag
    34681 tgatttaggt cacaataagc tgattgcacg tgccattaat tacattggtg gagatgctaa
    34741 gctgacagaa acaattacca attatagcca gcagctgctc aagcaattta taggtgttct
    34801 aaccggtatt ttgacatcgg ttacagcagt tgcctcagcc attatcaatg tggttatcag
    34861 ctttgtcttt tccctgtatg tgcttgctag caaggaagag ctttgtcagc aggcaactac
    34921 cttaattgac acctatactg gtaaatacgc aaaggccatt cattatttag tgggtttgct
    34981 gcatagtcgt tttcgtggct tctttgtgag tcagacgctt gaagcaatga ttttaggctc
    35041 cttgactgcc attggcatgt ttatcctgca attacccttt gcaggaacta ttggagtctt
    35101 ggttgctttt actgccttga tccctgttgt tggtgcttca atcggtgctg cgataggctt
    35161 tgttttgatt atgactcagt caatgtcgca ggcagtcgtc tttattgtct ttcttgttat
    35221 actacagcaa atcgagggga attttattta tcccagagtg gttggtgggt ctatcgggtt
    35281 accagctatg tgggtcttaa tggcaatcac cattggtgct gctctcaaag gcattgttgg
    35341 tatgatcgtt gcagtgccat tagcggcaac gctttatcaa gtggtaaagg atcacattca
    35401 taaaaagcag gccttacaaa atcgtcagtc cagctaatta acagcatcag atcaaggaaa
    35461 acgtctatta caagaccgat ttcttggtct tttatgctgt ctgattgact gcgtatggcc
    35521 ttatttttat gctgtggtaa tgaaaaaagc cgtcttattt atcgaatatc attagtggag
    35581 gtaataagat gtattccatc aaaactgatc ataaattaat gcctagagag cgtttgattc
    35641 gactgggtcc agaaaagcta agcaatcaag agcaactagc gatcctactt aggacaggta
    35701 acaaggaaaa gcatgtctta gagttgtctg cttatttatt gtcaagctta gatagtctag
    35761 ctgacttgaa gaaattttct ttacaagaac tacagcgctt atccgggata ggaaaggtca
    35821 aggctattga gattaaggcc atgctggagc tggcagaccg tattcagata gcgggacaag
    35881 cagtagcaga tcctgtctta tctagtgctc aggtggctga aaagatgatg attgaattag
    35941 gagacaagca gcaggagcat ttagtcgcta tttatctcga tagtcaaaat aaaatcattg
    36001 aagaaaagac gatatttata ggaaccgtca gaaaatcaat tgcagagcct agagaaattc
    36061 tttattatgc gtgtaaaaat atggcgacta gccttattgt tgttcacaat catccctcag
    36121 gcctgaccaa gccaagcgca aatgactatc acttcacaga aaaaataaaa cgatcatgtg
    36181 attatttagg acttatctgc ctagatcaca ttatcgttag taagtatgac tactatagct
    36241 ttcgggaaaa atcagattta ttttgagtta gaaactatgg ataaaccaat caaagagcct
    36301 taggtcttct tctctaatag cctgaagcag ctctgggtgc cactggacac cgagaaaggg
    36361 aatatcagga ttgcaggaga taacagcctc gatggtgcca tcgttaggat cccttgcaat
    36421 cactcttaag tcctctgcga cctgctttag gctctggtgg tgaaatgaat taatcagcgc
    36481 tcttggacca tagatagggt acaaaggtga agtcttttcg atcactatct cctgtgataa
    36541 acagtcagag gcagtctttt gccaatggcc ctcaatgtgc tggtttagac tgccacctag
    36601 agcaacattt attaactgca taccgcgaca aatccctaaa attggttttt tctgcgctag
    36661 ggcttcttta atgatggcta gctcaaagat gtcacgctgg ggtgaaaaat caccatcaag
    36721 tgcagctctt ttttcatgat aatatttagg atcaacatgc tgaccaccaa taagaatgat
    36781 tttatcaacc attgcgacat aggatttggc agccgcctca tccccaatcg gaagaagtaa
    36841 gggtaggcca ccagatcttg tcacagcctc gatgaagctt gttggagcat aggagcaagg
    36901 caggttatct agagccttgg tccccctttg gttagcagtt atcccaataa ttgttttaga
    36961 cacgaccttc tccattaatc aagatgattt tggttcataa agtatagcaa ggtttgcaac
    37021 tcgctggtca aatcaacaga ttggacgatc acaccttttg gaacctgtaa gtgaagtgga
    37081 gcaaagctta aaataccgcg aatgccagct tcaatcagtt gatctgcaac ctcttgagca
    37141 tagatgcttg ggactgttag aatagccgtt tcaatgcctg aattatccag gtgctcctta
    37201 atggtagaaa tgccataaat aggaatatca tcaggcgttt tggtgccgac cataggatta
    37261 tcatcagtgt caaatcccat aacaatctgc attttgtttc gatcgtggaa gcggtagtga
    37321 agaagtgcac gaccaatatt gccgcagcca actaaaatca catgcgttgt tgagtgatca
    37381 tttagcaaat ctgcaaaaaa attcattaat tttgtgacat catagccaaa tccacgtcgg
    37441 cctaattcac caaagtaaga aaaatcacgt cgaacagttg cagaatcaat tcccatagca
    37501 tcagcaatct gttttgagct tgccttttca acctgatcag cataaaagcg tttaaaaata
    37561 cgataataga gtgataagcg ttttgcagtc gcttttggaa tagatttatc aataaccact
    37621 tttgtagctc cttctattgt tattttaatg ttatctatca ccattgtagc agatagattg
    37681 tgaaatatgc aactatttga ccattctttt tgtgtttttc gttataaaat gacttgacag
    37741 cacaagcatt ggtatttttc aaacccagtc acctcgagta taaaaaagca gacaatgaag
    37801 cacttgccct ttaggtcagc tgcgatggct gggcttgtct tgttaaaggc aaatgtactg
    37861 tcattgtctg atatttctct gagattagaa gagctcttgt gtgcttagca ttctttttta
    37921 atgaaaatat cacgctcaac aaggctatcc attaaaaagt aaaacttgtc ctgtagtatg
    37981 ctatgctctt cagatttaaa aatgttcacc agtcttagac cggattggtc tgttatagct
    38041 agcttaaagc catctaaatc tttattaatc gtaattttta aagggaagcc ctcacccgaa
    38101 ttagggactt tttccagtag tcgtgttaac tgatagtgac caatcttggt ctgactaaag
    38161 gttgtgtctc ttagggtgta ttttttaatc tttgggctaa tcctgtagct gtatttgcag
    38221 tctttaaggg caatttcttt ttcaaatgcc atatgatcct cctaaaatat ttttgagctg
    38281 ggttgctagt gcgataacgt ctttttgagt attttgctct gaaaagctaa ctcgaatagc
    38341 ttctgtgaga cgatgggact gcttgccgaa ataagctgcc aaaacgtgac ttggctcaac
    38401 agcaccagct gtacaagcag agcctgacga cacagcaaag cctgctaaat caagctgagt
    38461 cagtaataca tgattttggt aaccaggaaa gccgatatta atgatatagg gaagatgaca
    38521 ctcattatga ttgagctgat aagaaatacc ttctaattca ctaagcaaga gctgtgatag
    38581 ctctttagca tgctggtaat gctgtggcag ccttgagaca gcctcatcta atgcttgggt
    38641 catgccgacg atattaatca ggctttcagt gccggctctt tgtttgtttt cttgattgcc
    38701 gccatgtaag aggggggcca actttaagcc tttattgtat aaaaaaccag tcccctttgg
    38761 tccatgaaac ttatgggcag aggcagagag caaatcaatc cccaaatctg ccggctgtat
    38821 tgggaccttg ccaatagctt ggacagcatc aacatgaaag acagcctgat gctgctttag
    38881 catgctacca acagcctgaa taggcagcaa atctcccgtt tcgttgttag caaacatcat
    38941 gctgactaag attgtatcct ctcttaaggc agcttggagc tgatttagat caatgattcc
    39001 atttttagcc tcaaggtagg tcacctcaaa gccaaatcgt tcttccagat aggccattgt
    39061 gcttaacacg gaatgatgct caatagcagt tgtaatcaag tgtttgcctt tttcctgatg
    39121 agctaaggca tagcccttga tagcagtatt gttactttca gtacctcctg aggtaaagat
    39181 aatgtggttt tctgcagctc ctaggcagtt ggcaatagct tttcggcact ctcttaattg
    39241 tttgtttgcc tgccgcccat aagcatgaat actagatggg ttaccaaaat catcagccat
    39301 agcttcagtc atcgccttga tagcagcctg actaagcgat gttgtagcag cattatcaaa
    39361 ataaatcatg attagttagt gctttcaggt ttgtaagaaa acagtggact tagtggtttt
    39421 ctttcgtgaa tgcgaatgat agcctctgca attaaatcac tggcactaag ataggttact
    39481 gttttaggga tacgattttt agtcttgaca gagtccgtga caatgatctc tttgattgga
    39541 gcagtctcta aaatatcagc tgcacctcct gcaaaaatcc catgactagc cactgcataa
    39601 atgtcagttg cgcctgcaca ttctaggatc ttagctgcct ctgcaaaggt ttttcctgtg
    39661 ttgagaatgt catcaatcaa gatagccttc ttgccagcaa catcaccaat cacatagcct
    39721 tcttcgcgct cagcatcgtc ttgtgcataa tcgataatgg caattggaga gttaagatac
    39781 tctgctaagc ttctagcacg cttgatacca gaatttttag ggctgacaat aaccgtatca
    39841 ggtcctgaga ggcccagtgg ataatagtgc tttgcaaaaa gaggcactgt aaataaatta
    39901 tcaactggaa tgtcaaaaaa gccttggacc tgaaccgcat gcaaatcaag ggttacaacg
    39961 cgatcaatcc ctgctttggt cagcatgttt gcgaccagct ttgctgtaat aggctcgcga
    40021 gactttgcaa cacgatcctg acgcgaataa ccaaaatatg gcaaaacaat attgactgta
    40081 ttagcacttg cacgcttaca agcatcaatc atgatgagca gctcccatag gttatcgttg
    40141 acaggaaagc ttgttgattg aatgatataa atatcatcac cacgaactgt ttcttcaatg
    40201 ttaatcatga tctcaccatc agaaaattga cgagatgaga cctttccaag cggaatacca
    40261 gcagccttag aaattttttc agcgattgcg agatttgaag tgagtgagaa cagcttgatt
    40321 tgcttgtcag catatcgttc agtcatgata aaattagctc cttacattac attaacgata
    40381 gaataacagg ttaacagtta ttcaagatta caaatagaca gtactatttt aacaaaaaaa
    40441 cagaaaaatt tcagtctttc tgttgatttt ctgtcctctc ctaggatttt ttaagggtct
    40501 tgctaaagcg agcgaccttg cttttggaat atttaaaggt gatctgatgc tgggctaaaa
    40561 agtggtcaaa atcaaccttt cctcttacag gatcagtcac ctctagctca agctcatagt
    40621 ctttgatacc agcatattga ttataatcca gcgctagctt gccaatagga gtatctgcct
    40681 ctcgacgaat ggtagtcagg tttccgaagg tttttatagc agataggtca acgtcaagag
    40741 tgctgataat atcaaggata gctgattttg gtagctgtcc tgtctgaatg atagcttttg
    40801 cttgggtgtc atcaagctct aaattgtact cgcgattacc aaccttttca gggactttta
    40861 aggttaattc agcaggagca gcaacaaagg tgcgaatgcg aagtgacatt ttatgagcct
    40921 tgagatcaaa atgatcagta tcaatgtaat aatttgtctg ggtaactggt gggacatgag
    40981 tcatttgaga gaggaggcga ttatattcgt cctttgtcag taaggtcttg tattcgattt
    41041 ctaggttagt catgcgaacg ttccttttaa ctatatttta tgctataata aattgttatc
    41101 ttaattttat attaatatcc gaggtttgac aagaaaggag agaaaggatg gctttagatt
    41161 gggaagaatt tttggatcct tatatacaaa cggttggcga attgaaaatt aagctgcgcg
    41221 gtatccgaaa gcagtttcgc aagcaaaacc gttattctcc tattgagttt gtgactggac
    41281 gtgtcaagtc ggttgagagc atcaaggaaa aaatggcctt gcgtggtgtc ttggaagaaa
    41341 atatcgctca agatattcaa gacatcgctg ggcttaggat tatggtgcag tttgtggacg
    41401 atattgagga cgttttgtcc ttgcttagac aaagacagga catgacaatt gtttatgagc
    41461 gagactacat tagaaacatg aaatctagtg gttatcgctc gtatcatgtt gtcgttgagt
    41521 atcctgttga taccattgag ggtcaaaaaa aagtattagc agaaattcaa atccgtactt
    41581 tagcaatgaa tttttgggca accattgagc attccttgaa ctacaagtac ggtggtgatt
    41641 ttccagaaga aataaaaaaa cgattagagg ttacagcaaa aattgctttg gagcttgatg
    41701 aagaaatgcg aaaaattcgt gaagacattc gtgaagcaca attgttattt gatcctgtaa
    41761 cacgtcattt gagtgatggt gtaggaaata gtgatgacac agatgaatta tacagataaa
    41821 gtaaagcgcg ttgctatcat tgcaaacggc aaatatcaga gtaagcgcct tgcctcaaag
    41881 ctttttggcg tctttaagga cgatccgagt ttttacctat ccaaaaaaaa tccggatatt
    41941 gtgatttcaa ttggcggaga tggcatgctt ctatcagcct ttcatatgta cgaaaaagaa
    42001 ttagacaggg tgcgatttgt aggcattcac actggacacc ttggttttta cactgattat
    42061 cgtgattttg aggttgatca attgatagcc aatcttagaa gagacaccgg tgagcaaatt
    42121 tcttacccta ttttaaaggt agttattacg cttgatgacg gtcgcctgtt taaggctagg
    42181 gctctcaatg aagcaactat taagcgtatc gagaaaacga tggttgcaga tattatcatt
    42241 aacaatgtca agtttgaaag ctttcgtggt gatggcatct ctgtatccac accaactgga
    42301 agcacagcct ataacaaatc cttaggtgga gctgtattgc acccaacgat tgaggccctt
    42361 cagctaacag aaatctcgag cctgaacaat cgtgtattta gaaccttggg gtcctcagtg
    42421 attattccta aaaaagataa aattgagctt gttccaaaaa gactaggcgt ttatactgtc
    42481 tctgttgaca ataaaaccta ccacttaaaa aatgtggtta aggtggaata ttttatcggc
    42541 aatgaaaaga ttcattttgt gtcctcacct agccacacca gcttttggga aagggttaag
    42601 gacgctttta ttggggatag tgaatcatga ggtttgaatt tgttgcaact aaaaaaacaa
    42661 aggtaaagac ccttttaaaa gagcacgatg tgtcaaaggg attgctcgct aagattaaat
    42721 acaagggtgg caatatatgg gtaaatggcg ttgcgcaaaa tgccatttat ttattggata
    42781 ttggtgatgt ggtggctatt gatattccaa atgaggagtc ctttgagcaa ttgacagcga
    42841 tttcgcatga ccttgatatt gtgtatgagg acgaacattt tctcattctc aacaagcctg
    42901 ctggctacgc tagcattcca agtgctatcc attctaatac tatagctaat tttatcaagg
    42961 cttattatat caagcaggac tatcccaata aacaggttca tattgtgacg cgcttagatc
    43021 gggataccag tggcttaatg ctctttgcca agcatggcta tgcccatgcc agattagata
    43081 agcagctaca gcaaagagct atcaataaac gctattatgc tcttgtttgt ggtcaggaga
    43141 ggcttccaga tcaaggtgag attatagctc ctattggccg tacggacgac agcattatca
    43201 caagaactgt cacgccaaag ggaaagtatg ctaagacaag ctacaaggtc attgcccgct
    43261 atcctgaaaa tgtctctcta gtggatatta cgctgcacac tggtcggacc catcaaatta
    43321 gggtacattt tgctcatctt ggttttccac ttttgggaga tgatctgtat ggtggtcgat
    43381 tggaccttgg catgactaga caggcgctgc attgtcacca tcttagcttt acgcacccat
    43441 ttacagaaag tagaagcgat catacaatat gcttgacaga tgactttgag agcgttatca
    43501 tagatttaca gaaaaaagat agaggttagt taatgagtat tcgtaattta tttggtggtt
    43561 taagggaaaa aattgtcggc aaaaacatga agattgtttt ccctgaggga aatgatgagc
    43621 gtgttgtacg tgcagcagca cgtctaaagt ttgaaggtct tgttgagcca attattcttg
    43681 gtcaggcaga tgatattcgc agcctgctaa cacagctagg ctttgctgag cagcactata
    43741 caatcattaa cccaaatgat tatgctgatt ttgagaaaat gaaagcagcc tttgtagagc
    43801 ttcgtaaggt caaggcaacg cttgaagatg ctgatagact gcttagagat gtcaattact
    43861 ttggtgttat gctggttaag ctaggcttag cagatggcat ggtttcaggg gctattcatt
    43921 caacagctga tacggtgcgt ccggcgcttc agattatcaa gacaaagcca ggcatttcta
    43981 gaacatcagg tgtctttttg atgaatcgcg aaaatacaga gcagcgttta gtgtttgctg
    44041 attgtgccat taatattgac ccaactgctc aggagctcgc agaaattgcg gtaaacacag
    44101 cagatactgc gaaaattttt gatattgatc ctaaggttgc catgcttagc ttttcaacaa
    44161 tgggctctgc taaagcccca caggttgaaa aggttcaaga ggccgtccgt attgctaagg
    44221 aattgaggcc agagcttgct ttagacggtg agcttcaatt tgacgcagcc tttgtaccaa
    44281 gtacagcagc gatcaaagcc cctgattcat cagtggcagg ccatgcgaat gtttttgtct
    44341 tcccagattt acagtctgga aatattggct ataagattgc tcagcgctta ggcatgtttg
    44401 atgctatcgg accaatcctg caaggattga acaagcctgt taatgattta tcacgtggct
    44461 ctagtgcaga ggatatttac aagctagcta ttattacagc agcgcaagcg cttgaaaatg
    44521 agtctatcaa ttaactgcta atagccatta agttcacaag gcttagctat agtagatgtt
    44581 gcttaaaacg agttggataa gccagctcgt tttttcagaa agtgaggaag gaaatgacaa
    44641 agattgcatt agtaacaggc gcctctgctg gctttggtaa agccattgca gagcagttaa
    44701 tagcccaaaa catcaaggtg atcggagcag cccgccgcat agaaaagcta agagagctag
    44761 aaggtatttt tggttctgag aggttttatc cgcttcaaat ggacgtttca gaaccaactg
    44821 ccattgataa agcacttgca gaattaccta aagaatggca ggccattgat attttagtta
    44881 ataatgcagg actagcctta ggacttgata aggcctatga ggctgatgtc gccaactggc
    44941 taaccatgat taatactaat attattgggc ttatctattt aacacgtcag gtattaccgc
    45001 aaatggtaag cagcaacaat ggcatgatca tcaatatcgg ctcaactgct ggcactattc
    45061 cctatccggg agctaatgtt tatggggctt caaaagcctt tgttaagcag ttttcgctta
    45121 atttaagggc agatttagca ggaacaaata tcagggtgac caatattgag cctggccttt
    45181 gtgagggaac agagttttct catgttcgct ttaagggtga ccatgagcgt gttaaagcac
    45241 tttatgcagg tgcacatgct attcagccaa gggatatcgc aaatactgtc tcatggatta
    45301 ttgatcagcc agagcatgtt aacattaacc gcgtggaaat gatgcctgtc tcacaaagct
    45361 atggttctca gcctgttagc cgtcatgact aagaattaca agagcagatg taaaaggatt
    45421 gtcgaagtgc aacccaaaaa gacttaaagc ctagctgttt tatagcctgg ctttaagtct
    45481 ttttctctaa tttttcttag aaatgatccg aaagagaagg tccagatgtg acatctgacc
    45541 acccaacaat ggcctgccct gtttcttcca aatagtgctg cagcataggc ttgaagtcca
    45601 aaatcatgtc atagacccca acaaattgct tggtatcatc gtacaaggct tgatattgct
    45661 gcatataaat atgatcctgt gaagcagtcg gaataagata cagcttactg ccagttgccg
    45721 ccttgtgcaa atcagtcaag atccaatcct caatgacatc atgcttatca gaagcaaaaa
    45781 aattgccatt aaagcgatga ttatcaaaga tgatctgccc ctgatgatca gcaattctag
    45841 cctgaagggg aagataggtt aaaaaatgtg gggctaaggc ttggtaaaat tgcatgaggt
    45901 atttagcaag tcttaaagtt tgctgactat cagtaaaggt atgatcacta acggtaaatc
    45961 cttgctcttt gtctgcctga ttaaaataaa gtacaggtag tgaggcttca aggttctgaa
    46021 aggtaaaaat ggcctgagcc tttttgagct gctcagtagt cagctgacgg acaatagtga
    46081 tatgaaacag atagctaaac tcttgtgata aggtggtaaa aaaagtcttt tgcagattat
    46141 tcttatcatc aaccagtgct aaggtataaa tcgttttagt cataaggcta tcatagcttt
    46201 attttgttta aatagcaatg aaacagcctt ttagtctaca gacttagttg atagcttaat
    46261 aaaagaaagc aatatgaaaa aatgattaaa gcaaactagt tgacttgtta gtttaaactt
    46321 tttataataa atcaaatgag aagataatat gaggcttagc ctaagctgct gagcttatct
    46381 gataatcatt cttcttagca ctgagataac cccctttatc gattaattgg agaatctatg
    46441 atacgtttta ataatgtttc caaaaccttt ggtcacacca aggtgctgca ggagcaaagt
    46501 tttcaaatac agaatcgcga attttttgtg ctggtcggtc caagcggctc tggcaaaaca
    46561 aagctcttaa aaatgatcaa ttgccttact gaaccaagct ctggcgaaat tctattaaac
    46621 ggaaggccac aaaaagagct agatttgcga gatatgcgct tatctattgg ctatgttctt
    46681 cagcaaattg ccctgtttcc aaaccttaca gttgctgaaa atatcgctat tattccagag
    46741 atgaagaagt ggtcagacaa agagattaga actaagacag aggaattgtt agataaggtt
    46801 ggattgcctg caagggatta tctaaatcgc tatcccagtg atttatccgg tggagagcag
    46861 cagaggattg gtattgttcg tgccatcatt tctcacccca aggtgctgtt aatggacgag
    46921 ccgttttcag ccttggatcc tatttcacgc aagtaattac aggacttgat gttaagtctt
    46981 cacaaggagt ttgatatgac aattgtcttt gttactcatg atattgatga ggctatcaag
    47041 cttggagatc gtgtggctgt tttaaatgaa gggcaaattg ttcaactgga tcgaccagat
    47101 gcgatcatag ctgcgcctgc taatgatttt gtagcaagtc tatttggagg tcgtgattat
    47161 gcctagttta ctgatgacct tttgggatcg ttttggtgat tgggcaaggg cattaggaga
    47221 gcacttgcag atttctcttc tttctttgct ggctgccttg ctgataggca ttccgcttgc
    47281 agctctgttg agtaaaagta agcgctggtc aaatatcatc ttgcagctga caggtgtttt
    47341 tcaaaccatt ccttccctag ccttgttggg actatttatc cctctaatgg gaatcggaac
    47401 tgctccagct gtaacagctt tggttattta tgccatattt cctattttac aaaatacgat
    47461 tactggctta aatgctattg atccaagtct tgtagaggcc ggaacagcct ttggaatgac
    47521 caagtgggag cgactgaaaa tatttgaaat tcctattgct atgccagtta ttatgtcagg
    47581 tgttcggacc tcagcagtga tgattattgg aacagccacc ctagcttctt tgatcggagc
    47641 tggcggctta gggaccttta tcctattagg aattgaccgt aataatgctc agctgattgt
    47701 gattggtgct gtgtcgtcag ccttgcttgc gatagtgttt aacagtcttt tgtgatacct
    47761 tgagaaggcc tcactgaggc gtattgcgat aagctttgct gcgaccttat tactgctctt
    47821 aatttcctat actccaatgt ttgtcaagcg gtttgttaat cagtcaaata ctctggtgat
    47881 tgctggcaag ctaggagtag agccggatat tttgatcaat atctataaag agctgattga
    47941 agaccagtcc aagcttaagg ttgaattgaa acctaatttt ggcaagacaa gctttttata
    48001 cgaggcgatt aaatcaggag atattgatat ttatccagaa tttacaggaa ccatcacctc
    48061 tagcctatta aagaaaaagc ctaagctttc taatgaccct aatcaggttt acttagctgc
    48121 taaggagggg attgctgagc aggatcagtt gacgctttta aagccctttg cctatcaaaa
    48181 tacctatgca gtggcgatgc ctgaaaaaat agctgacgaa tttaacattc aaagtatttc
    48241 agatgtgaag aaatatgaaa aacagctaaa ggctggtttt acactagaat ttaaggatag
    48301 agaggacggc tataagggca tacaggataa gtatgatcta catttatcag ttgcaacgat
    48361 ggagccagct cttaggtacc aagccattca gtcaggaaac attcagctga cagacgctta
    48421 ttcaactgat gctgagatcg tgaaatatca gcttcgagtc ttaaaggacg ataagcagct
    48481 ctttccacct tatcaaggag cgccattgat gaaggcttcc ttactaagaa agcaccctca
    48541 tctcaaaacg attctcaatc agttatcagg aaagattact gaagaggaga tgcaagcaat
    48601 gaactatgag gtgtccgtaa agggcagagc agctagcctt gtggcacatg actaccttgt
    48661 aaaggccggt cttattgcaa gaaccaaata agcaggcatg ctagtcttat tctggactgg
    48721 catgctttat ttatgtgatt tttagtctgt ctggctctgc aaggtgtgtg ccaaataacc
    48781 gctcgtttga tgtgtggtta ttgatttagt agctaaggat tggaatctta aaataaaatc
    48841 cgaacgtttg tctaaaaaaa gctttaaaaa ttgacaaaac ataaacgaaa ggataaaata
    48901 aattaaggaa aggtaacatt ttacctagcg atgcctcgga caagcttgag gtcataggaa
    48961 ggtcatttta tatagaagct tatgtcagct gcagatcagg gaagtccttg ctggattagt
    49021 agctgaatgt tgaaaaagga gagaaatgat gtttaatgac atgcctgtat ttgattatga
    49081 ggatattcaa ttaattccta acaaatgtat catcaatagt cgttcagaag cagatacgag
    49141 tgtaagactt ggtaattata cctttaagct acctgttatt cccgccaaca tgcaaaccat
    49201 tattgacgaa acaattgcag agcagttggc aagagatggt tatttctata ttatgcaccg
    49261 ctttgatgag gaggggcgca agccctttat ccagcgtatg catgagcaac agctcatcgc
    49321 ctctatttcg gttggtgtaa aggattatga atacgatttc gtctcttctt tgaaggagga
    49381 cgcacctgag tttatcacga ttgatattgc tcatggccat gctgatagtg tgatcaaaat
    49441 gattaagcat attaaggctg agctgcctga gacctttgtt atagctggaa atgtcggaac
    49501 accagaggct gttcgagagc tcgaaaatgc tggtgctgac gcaacaaagg tcgggattgg
    49561 acctggtaag gtttgtatca caaaggttaa gacaggcttt ggaacagggg ggtggcaatt
    49621 agctgctgta cgttggtgtg ctaaggctgc tcgtaagccg attattgctg atggcggtat
    49681 tcgtactcat ggtgatattg ccaagtcgat tcgatttggg gcaacaatgg tgatgatcgg
    49741 ttcactcttt gcaggtcata ttgaaagccc aggcaagatg gtagaaatcg acggacagtc
    49801 cttcaaggaa tattatggct ctgcctctga atatcaaaaa ggggagcata aaaatgtcga
    49861 aggcaagaag attttgcttc caaccaaggg tcatctagct gatactttaa ccgaaatgaa
    49921 gcaggattta cagtcatcaa tctcatatgc tggaggcaga gatttggaga gcctgcgtcg
    49981 tgtgaattat gttatcgtga aaaattctat ttggaatggt gactctattt aaagccttgg
    50041 ctaaagacct agtctaaata aggataagca agctgattga tgctgagaat aagcacagcg
    50101 tgtctatagg acgcctgaat gtctagtagc cagtaaagct tttaggcttg ctgattggat
    50161 aggtcattgt gcctatgtgc agcagggctc tagggactta gataaaaagg agacatgatg
    50221 aggttactgg aggagcgtat cctagctgat ggaactgttt taggtgagac gattttgaag
    50281 gtggatcaat ttttaacaca tcaggttgac tatcgcttga tgaaggaaat cggtagagta
    50341 tttgctgatc aatatgctga tttgggcatt accaaggtgg tcaccattga agcctctggt
    50401 atcgcaccag cagtttatac cgcagaagct cttgaggttc cgatgatttt tgccaaaaag
    50461 cacaaaaata tcacgatgac agagggaatt ttaacagcag aggtttattc ctttaccaaa
    50521 caagtgacaa gtactgtttc tattgcagga ggactgctat caaaagaaga tagggttttg
    50581 attattgatg actttttggc taatggtcaa gcggcaaaag gcttgattga tatcattcat
    50641 caagcagggg ccaaagctgt tggcataggc attgtcattg aaaaatcttt tcaggctgga
    50701 cggcaattgc ttgaggattt gggagtagag gtcacttcat tggctcgtat taagcatttt
    50761 gacaatggaa tagtaagctt tttggaggct gatgcctgat gactgcttct tatctctcag
    50821 cattaagctt tttacttgta tagctatacc agctttattt cagtagctat tggctggtga
    50881 taagggatat tggtatggcg gtgcattacg gcgagccgtg ggcagttgcc cttgcggctt
    50941 tacgatttag tatagactat caagaattga ctgcttcctt tttatcgaga tgaatcatta
    51001 gacagacaat catgatttgg cgtgaaggct gctttcagta aacattacat catcaaaaat
    51061 cagctaggta ttcacttagc tgatttttag tgcttataat gtagccgaaa ggctcccttt
    51121 aacccgtctg agatagtaac ctgaccatct ttggtaatga taatgccttc cacctcaggc
    51181 agcttattta gctgacttag gacaaaggaa tgctctaagc caaaaagacg actactccat
    51241 agctcaccat caagtgagaa ttggctgaca atggttaggc tagccatatt ggtcttgata
    51301 ggatagccgt tgtgaggatc aagaaggtga tgataagttt tgtctttgat ttgtaattgt
    51361 ctctcgccga ttcctgaggt tactacagat ttattgttaa ccttaatcac gccgacatgc
    51421 tgtcctcttt tttgattggt ctgctggatc ccaacgtaaa acaagccatt atgtcgttgc
    51481 ttgttggtgc catgcacaag gacatttcca cctagattga taagagcagc agtgataccg
    51541 tctttaataa gaaatgccat gagcttatca gcaatatagc cctttgctag ggcacctaag
    51601 tcgatagaca tgcccttttc tttcaaaaaa atacttccaa ggctttgatc taa
//
LOCUS       DARYLD010000005        50720 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYLD010000005 DARYLD010000000
VERSION     DARYLD010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50720
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            175..963
                     /locus_tag="TU651_000248"
     CDS             175..963
                     /locus_tag="TU651_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0896287.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TU651_000249"
     CDS             972..2141
                     /locus_tag="TU651_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL0896288.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TU651_000250"
     CDS             2144..2347
                     /locus_tag="TU651_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896289.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TU651_000251"
     CDS             2479..3912
                     /locus_tag="TU651_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0896290.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5111)
                     /locus_tag="TU651_000252"
                     /pseudo
     CDS             complement(3942..5111)
                     /locus_tag="TU651_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5167..5808
                     /locus_tag="TU651_000253"
     CDS             5167..5808
                     /locus_tag="TU651_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL0896291.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5929..6855
                     /gene="cysK"
                     /locus_tag="TU651_000254"
     CDS             5929..6855
                     /gene="cysK"
                     /locus_tag="TU651_000254"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL0896292.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7242..7604)
                     /locus_tag="TU651_000255"
     CDS             complement(7242..7604)
                     /locus_tag="TU651_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL0896293.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7604..9004)
                     /locus_tag="TU651_000256"
     CDS             complement(7604..9004)
                     /locus_tag="TU651_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0896294.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(9037..9678)
                     /locus_tag="TU651_000257"
     CDS             complement(9037..9678)
                     /locus_tag="TU651_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0896295.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9671..10675)
                     /locus_tag="TU651_000258"
     CDS             complement(9671..10675)
                     /locus_tag="TU651_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0896296.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10672..11364)
                     /locus_tag="TU651_000259"
     CDS             complement(10672..11364)
                     /locus_tag="TU651_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL0896297.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYVIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11497..13392)
                     /gene="pknB"
                     /locus_tag="TU651_000260"
     CDS             complement(11497..13392)
                     /gene="pknB"
                     /locus_tag="TU651_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL0896298.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13389..14129)
                     /locus_tag="TU651_000261"
     CDS             complement(13389..14129)
                     /locus_tag="TU651_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL0896299.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14167..15489)
                     /gene="rsmB"
                     /locus_tag="TU651_000262"
     CDS             complement(14167..15489)
                     /gene="rsmB"
                     /locus_tag="TU651_000262"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL0896300.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15479..16414)
                     /locus_tag="TU651_000263"
     CDS             complement(15479..16414)
                     /locus_tag="TU651_000263"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL0896301.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16481..18865)
                     /locus_tag="TU651_000264"
     CDS             complement(16481..18865)
                     /locus_tag="TU651_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL0896302.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18929..19246)
                     /locus_tag="TU651_000265"
     CDS             complement(18929..19246)
                     /locus_tag="TU651_000265"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL0896303.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARFEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19271..19897)
                     /gene="gmk"
                     /locus_tag="TU651_000266"
     CDS             complement(19271..19897)
                     /gene="gmk"
                     /locus_tag="TU651_000266"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL0896304.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(20059..21669)
                     /locus_tag="TU651_000267"
     CDS             complement(20059..21669)
                     /locus_tag="TU651_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL0896305.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21826..22311
                     /locus_tag="TU651_000268"
     CDS             21826..22311
                     /locus_tag="TU651_000268"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL0896306.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22456..23907)
                     /locus_tag="TU651_000269"
     CDS             complement(22456..23907)
                     /locus_tag="TU651_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896307.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPQVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23921..25075)
                     /locus_tag="TU651_000270"
     CDS             complement(23921..25075)
                     /locus_tag="TU651_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL0896308.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25139..25507)
                     /gene="rnpB"
                     /locus_tag="TU651_000271"
     ncRNA           complement(25139..25507)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TU651_000271"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25520..25843)
                     /gene="gpsB"
                     /locus_tag="TU651_000272"
     CDS             complement(25520..25843)
                     /gene="gpsB"
                     /locus_tag="TU651_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL0896309.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25965..26480)
                     /locus_tag="TU651_000273"
     CDS             complement(25965..26480)
                     /locus_tag="TU651_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL0896310.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26556..27164
                     /gene="recU"
                     /locus_tag="TU651_000274"
     CDS             26556..27164
                     /gene="recU"
                     /locus_tag="TU651_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL0896311.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27151..29316
                     /locus_tag="TU651_000275"
     CDS             27151..29316
                     /locus_tag="TU651_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0896312.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29359..30693)
                     /gene="pepC"
                     /locus_tag="TU651_000276"
     CDS             complement(29359..30693)
                     /gene="pepC"
                     /locus_tag="TU651_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL0896313.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31382..32206)
                     /gene="nadE"
                     /locus_tag="TU651_000277"
     CDS             complement(31382..32206)
                     /gene="nadE"
                     /locus_tag="TU651_000277"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL0896314.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32203..33663)
                     /locus_tag="TU651_000278"
     CDS             complement(32203..33663)
                     /locus_tag="TU651_000278"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL0896315.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33939..35333)
                     /locus_tag="TU651_000279"
     CDS             complement(33939..35333)
                     /locus_tag="TU651_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0896316.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35453..36370)
                     /gene="trxB"
                     /locus_tag="TU651_000280"
     CDS             complement(35453..36370)
                     /gene="trxB"
                     /locus_tag="TU651_000280"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL0896317.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36430..36657)
                     /locus_tag="TU651_000281"
     CDS             complement(36430..36657)
                     /locus_tag="TU651_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL0896318.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36767..37510)
                     /locus_tag="TU651_000282"
     CDS             complement(36767..37510)
                     /locus_tag="TU651_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0896319.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37510..38313)
                     /locus_tag="TU651_000283"
     CDS             complement(37510..38313)
                     /locus_tag="TU651_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0896320.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38690..39517)
                     /locus_tag="TU651_000284"
     CDS             complement(38690..39517)
                     /locus_tag="TU651_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0896321.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            40025..40480
                     /locus_tag="TU651_000285"
     CDS             40025..40480
                     /locus_tag="TU651_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896322.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41121..42464)
                     /locus_tag="TU651_000286"
     CDS             complement(41121..42464)
                     /locus_tag="TU651_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0896323.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42547..43554)
                     /locus_tag="TU651_000287"
     CDS             complement(42547..43554)
                     /locus_tag="TU651_000287"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL0896324.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43556..45811)
                     /locus_tag="TU651_000288"
     CDS             complement(43556..45811)
                     /locus_tag="TU651_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0896325.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45815..46138)
                     /gene="ftsL"
                     /locus_tag="TU651_000289"
     CDS             complement(45815..46138)
                     /gene="ftsL"
                     /locus_tag="TU651_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL0896326.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46142..47092)
                     /gene="rsmH"
                     /locus_tag="TU651_000290"
     CDS             complement(46142..47092)
                     /gene="rsmH"
                     /locus_tag="TU651_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL0896327.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47195..47611)
                     /locus_tag="TU651_000291"
     CDS             complement(47195..47611)
                     /locus_tag="TU651_000291"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896328.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47631..48878)
                     /locus_tag="TU651_000292"
     CDS             complement(47631..48878)
                     /locus_tag="TU651_000292"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL0896329.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48878..49696)
                     /gene="proB"
                     /locus_tag="TU651_000293"
     CDS             complement(48878..49696)
                     /gene="proB"
                     /locus_tag="TU651_000293"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL0896330.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50297..>50720
                     /locus_tag="TU651_000294"
     CDS             50297..>50720
                     /locus_tag="TU651_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896331.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14991 a        11589 c         9688 g        14452 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctt gaccttgcgc
     4381 tctaaatctc ttgtagaggt tgctgttagg tatactgtca ctgcatctgc ttttgcagcc
     4441 tgatgagcag catggtttaa ttgacgatta ttgacaaagg ggaaggcatc tacttcgtca
     4501 ataatgagca gatcaaaagc atggtaaaag gtcatcaatt gatgtgttgt ggcaacgata
     4561 atggggcttc tatgataaac ctctgactca gcatgcataa ggcagacttg acaggaaaag
     4621 tcccgcgata gtcgtttttc aagctctatg caaacatcaa ctcgtggact agcaatgcag
     4681 acccagccac ccttattaac aactgctgca atagcttcat acatcatctc tgttttgcca
     4741 gcaccagtaa ccgcatgaac taaggtgtct tgcttgagct taacatggtt agtaagctga
     4801 tgagagatag ctgcctgata tgtcgtgagc tgtccttgcc acctcagata atgtcccttt
     4861 ggaaaagaag ccggtggaaa atagagcaag gggcgatcag attggtttcg accaaaaaca
     4921 agacaggctc tacagtagta agcaccgcta ggcagctgat gagccttctc aattaaactg
     4981 ctacagcgtt ggcagtataa cgttcccttt ttagtgatca tgctttgtaa gctgcaagcc
     5041 caggcagaaa cagcctttgg gcattgcctt tcgggtaaaa gacgtccata gtaattttcg
     5101 atattctcca taccttatta tccgaattat tttgctaaat atcagcattt tttgtaaaat
     5161 tttcttatgg aagattataa aactattatg actgatgggc tttttgagga aagcatcaaa
     5221 aaatctcgct ttatttgcca aatcaaacgc gtctacacag aagaggaggc cagagccttt
     5281 attgctgaca tcaaaaaaaa gcactataag gccaatcatt cctgctctgc tatgattatc
     5341 ggagacaaag gacaaaccaa gcggtcaagc gatgatggtg agccatctgg tactgctggt
     5401 attcccatgc tatctgtctt agaaaggcag gaattaacca atcttgtagc tgttgtgaca
     5461 cgctattttg gaggtgttaa attaggagct ggagggctca ttcgcgctta ctccggcgta
     5521 actgcggcag ctattcaggc cttaaaggtc gttgaggtaa aaaaacaaac tggactagca
     5581 atcagcctca cctaccctca ataccaaatc tatcctaatt ttctggagca agaagcattg
     5641 attgaaatga ataccgaatt ttctgatgtc gtcagaacag ctatttactt tgatcctgag
     5701 cgcttggaga gtatttctaa ggcattgatt gagcattatc atggcaaggt ttcctttgaa
     5761 gagatcgaat cgcaaaggat tgaggtccct gttttgcctg ccaattagca tgaacagtga
     5821 tagcgtctct ttatcactac gatagtaaat ggctatttta ctttgtcgat tattagctat
     5881 atacttttat ataagcatgt attgatacaa ggataaaaag gaggacctat gtcaaagcta
     5941 tatcacaaca ttacagagtt ggttgggaaa acccctatta ttaaattgag aaacaccagt
     6001 ccagaggagg ctgccgatat ttatgtcaag ctagaagctt ttaatccagg ctcttcagtt
     6061 aaggatcgca tagcacttgc aatgattgaa gctgctgaga aagcaggcat gatcaagcca
     6121 ggtgatacaa tcgttgagcc aaccagtggc aatacaggga ttggcttatc ctgggttggg
     6181 gctgcaaaag gctaccgagt gctcattgta atgcctgaga caatgagtat tgaaagacgt
     6241 caaatcattc aagcttacgg agcagagctc gttttaaccc caggtagtga tgggatgaaa
     6301 ggtgcgattg ctaaagcaga agagattgcc agagagaccg gtgcttggat gccctcgcaa
     6361 tttgacaatc ctgcaaatcc caaggttcat gaagagacaa cagggcaaga aattatcgcg
     6421 gtttttggag aaaaaggact tgatgccttt gtttctggtg tgggaactgg tggcactatt
     6481 tctggcgttg cgcatgcctt aaaggctgtt aatcctgata tttctatcta tgctgtggaa
     6541 gcagatgaat ctgccgtctt atctggtgaa gagtcttctc cgcacaagat tcaagggatt
     6601 tcagctggct ttatcccaaa taccttagat acaaaggcct atgaccacat cattcgagta
     6661 gcgtcagagg ctgcccttgc cactgctcgg tcaatcgggg ctaaggaggg ctttcttgta
     6721 ggcatttctt ctggagccgc tgtttatgct gctatccaag ctgctaagga gcttggaaaa
     6781 ggtaaaaagg tcttagctat attaccagat aatggtgagc ggtacctgtc tactgccctt
     6841 tatcagtttg attagaataa tcatataagc accagcccta gcagctagaa taagctttca
     6901 agcataaatc atcgctctta cttagtcacc attaaaggcc agtcagctag catatggaaa
     6961 aatgcttact ttgattcctt tttaacaata aacatagcat accacgccta agcgccccag
     7021 agcttctagc ttcttggaaa taggctttcc tagccgcttt caccacagta aaaaagactc
     7081 aagctagtag gctaagatgt tcaaagagga ctagcaatca caattggctt tttttgaaga
     7141 tagctttgag ataagtaagg tgactggtcc agagctgata gcaaaaaacc gaggaacagt
     7201 tcatatagct gtttctcggt tttttatgtt tccaagtctg tttacgattt ttcctgctta
     7261 aagtggtcta agccttcctc aatccaattg ggtaagctgg cttcaagagg cttaaagcca
     7321 atcttataac ggctgtttga aaagcgatga tgacttgaca catgatgctt ttcctcctcc
     7381 aaagttctca aggacaggct gaccttatga ctgtattcgt catagtcaat gacctgaact
     7441 aaaaccgcct caccaagtct taggatctga tgaatattat caataaatcc cgtcttaatt
     7501 tctgaaatat gaatgagacc tgttgtccca ttttcaaggg caacaaaggc tccatagggt
     7561 ttgattcctg taatggtccc atgcagctta tcgccaattt tcatcaatca aatacctcga
     7621 tggcctcaat gacaacgtcc tcttttggct tgtcttgtgc ccctgtttcg acagcagcaa
     7681 tgttatccaa gacctgataa gaggcttcat cagccaactg accaaatact gtatggcgac
     7741 gatccaggta aggagtcccc ccatgttcag cgtaggctgc tgcaatgtcc tttggccagc
     7801 caccacgctc taattccttt tgagaataag gaaggcttgt attttggacg ataaagaatt
     7861 ggctgccgtt tgtatttggt cctgcattag ccatcgaaag ggctccgcga aggttgtaca
     7921 attcctctga aaactcatcc tcaaagcttt gaccatagat ggattgccca cccattccag
     7981 tgccagtcgg atctccacct tgaatcataa aatctgcaat aatacgatgg aaaataacac
     8041 cattatagta gccttcctta gctagaccta agaagttagc aactgttttt ggagcatgct
     8101 ctggaaataa agccaatgtc agctcaccat gatttgtttt catcaccact cttggtcctt
     8161 catggccagc caaatctagc tgcggaaaat gtaattcttt gtcaatcaaa cctaattcct
     8221 ccaaggcata taaaatgccg ttttcttcaa ctgttttagt aataaaatct gctttttctt
     8281 gtaattgtgg gtgagaaacc cccatagcaa tgctgatgcc agcataatca aatagctcta
     8341 aatcattgag ctcatcacca aagaccagga tattttcagg ccttaagccc aaatgctcaa
     8401 caacctttga tacacctaga gccttagagg tgccctttag gaccacatca gaggagtgat
     8461 catgccacct tactaggcga agctgctcag ccaattcaac aggtaattgc aggtcatctc
     8521 ccttgtcctc aaaggtccac atttggtaga catcatggtg ctcattgtaa tccgggcata
     8581 cctctagtgt ggagtaaacc ttatcaatag catcactaat catctcgtta cgagctgata
     8641 agacagcctc gtgacgtcct gccatgccat aatcaatgcc gactgcattg gcccattttt
     8701 tataggctac aacagtgtct gctgggatag gtgcctgaaa gataatgttt ttttgattgt
     8761 ccttcacata agcaccattt agcttaacac aataatctgc ctgtaaatcc tgaacctcct
     8821 tgggcacacc atatctggcg cgacccgaag caattcctgt taggatccct tttttcttga
     8881 gctctttgaa aaccctctgg atagactctg gcatatagcc tgtgttcttt acgcgcaggg
     8941 tatcatctat gtcaaagaaa accatcttga ttttcttggc cttatacttt agttttgcgt
     9001 ccatactttc ctccatgcaa tagtactatt atagcattaa tgatcatctt gaggcactaa
     9061 atgatgtcgg aaagcgtata caacagcctg agtacgatca tcaacctgca atttggctaa
     9121 aatatttgac acgtgagtct taactgtctt caaggaaata aaaagctcat cagcaatggt
     9181 ctggttatca tagcccttgg ccaataaatg caaaatatcg tattcacgcg ctgtaagctc
     9241 ttcatgtaaa ttaggctgct gatcatgtgc cttaatcttc ttgtcaacct ccgtttcaat
     9301 ggcaagctcg cccttagcaa cctttctaat ggcatttaag atttcagctg cacttgatgt
     9361 ttttaacata tagcccttag ctcctgcatc aatgacaggg taaatttttt cattatcaag
     9421 ataggaggtt aacaccaaca cccttgcttc cttccatttg gagagtattt ctagggtcgc
     9481 ctctacacct cctaattcag gcattaccaa atccataacc acgacatctg gtctcaattc
     9541 aagggcaagc tcaactccct cacgaccatt agaagcctca cctatgacat caacatcttg
     9601 ctgcaaattt aagaagcttt ttaagcccat tcggaccatt tcatggtcat caactaatat
     9661 tacggttata ttactcatct tcatctccca tcacaagtgg cagtctaatg tccatcgaaa
     9721 cgccctttcc tttttgacta atcaaacgaa gcgttccagc caggtcattc acacgatctt
     9781 caatattttt aaggccatag cttaattccc taacctgacc catgtcaaaa ccaaccccat
     9841 tatcaaccat ttttagctgt agttctgttg gtgtttggtt caagtacacc tcaaggcggc
     9901 tcgccttagc atgcttgagg gtattgctga taaattcctg agcgatccta aagagattat
     9961 cctctatggc ctttggcaga gtgccaatat tttctttata gacaacctca atgccgcttt
    10021 tatcagttag ttccttgaga atcatcgtaa agccctctga caggctacga tttgccaatt
    10081 ctgtcgggcg caggtgcaat aataaaatgc gtaaatcatt ttgagcattt tgcagcatgg
    10141 cttcaacagt aactaattgt tgctgtagct gctccttatc catctgatct aggctcatag
    10201 aaacccctga caaaatcatc gacgaagcaa acaattcttg actaacagtg tcgtgcaggt
    10261 ctctagcgat tcgtttacgc tcctgttgaa caattttttg actatctaaa atataagcat
    10321 tctctttttt ctggatattg gttgttatat gagacatttt cgcagaaagt ctggtcaaat
    10381 tcgtgttgat ttcagaggtc tcctccaaat gaattctttg attgttgaga atcctgcgta
    10441 aatttttatt gatgctccgc ttgctattat catctaaaat aatccacaac aaaagcaaca
    10501 gcaaggttac agagatgata agcagcacaa ctgaaaacac caagcgctct agctgccata
    10561 aatggctccg caagtagtca aaggtgatcc ccagattatc catcacaaca aaaacaattg
    10621 ataaaatggt tatagtcgaa taaagccaga ccaaagcata ataccttttt ttcatcgtct
    10681 agccacctcg acatttcctg ctatagtgga tacgataatc ttaaccttct ttaaactgct
    10741 gtcctcggcc tctcctaggg tgatggattc atttcgtaaa tcgtactctt gaagctcaaa
    10801 aaaatcaaca ctagcataga tagagctgac ctctaaggta acagccacat caataggcac
    10861 taggatcttt gtgttgccaa agatctttct gataatgatg acattgtcca ttccagtcac
    10921 aatcacattt gtcagatcaa tcgtatcatt gccagaggca cgaataatat tgatatcctc
    10981 aaaggaataa taatcacttt catagttagc tgcgccaagc cattgatttt tgacctgtcg
    11041 cacagtcatt ttttcttctg caaaccgaat gagggcaaat cgattcttct tttttacctg
    11101 tgaaaaatga ttgataatca catacacaat ccccaacaga accgccataa taacataagg
    11161 gttcagcata aaaattaaga ataaaagcaa taagctaact gttagcaaaa agctattgcg
    11221 ggtatcttga ttataaaaac gcagagccaa taaaatcaag accaaaatta aaataaagct
    11281 tgataagtcg ttggccaaaa tggtcataat ccccatagcc agcagcatgc attcaacaag
    11341 cagaaagaat tgaaattttt tcattagact ccttccatta ccctgacatt ttatcaaaaa
    11401 ttaagcaaaa attcaccctt gagtggcatt ctagtaaaaa agaataccta gcttagcaac
    11461 tatgggcaag ccagatattc tatatcctat ttacgtttac ggtgttgtaa cagcgtcatt
    11521 ttgacctaat tcggtatgac tgcttgagtc tgttgtatct ccagctgatg gattaggagc
    11581 cgaggtatca gagctcgatg agctgcttga tgcacgtgtc tcctcagggt agaggtagag
    11641 gctaatatca cccttttcag aaaggctaat ctgggtacca taatacggtg tttgcccact
    11701 gacaaccgcc tttgagcttg gggagctcac ctgcacaaag cctgtcggag agctggagct
    11761 tggtacatag gccttgattc ttgcggcatc aattcctaaa gctgttagtg tattgactgc
    11821 atctgcatag ctgtactcag ttaccattgg catgatgact gtatcaccca ctgctacact
    11881 gagggtaatc ttggatttac cagctgggtt aaatttttct cctgcgcttg gagactggct
    11941 aataacggtg ttttcagggt attcatttgt cacgatacgc tcaatcttga tttttgactt
    12001 tggtacgcca taggtctcag tcagactggt catcacatct tgataatcct gtcccttata
    12061 attttccatc tcaaagcctt tatttccgat cgaaaggtaa aggtcaacgc tggagccttt
    12121 tcgcttagct gagccagctt gaggatttgt cttaaccacc tgatcctcac taactgtgtc
    12181 actttcaatc tgatggacct taccgacctt tagtcccgcc tcctccaaga cctgcttggc
    12241 agcattgaga ctagagcctg tcacatcagg aaccttaacc gtagttggct tggtcaagac
    12301 caaataagca aaaagagcca caccaacaac aaaaaaggaa aacaagattt ttaagagtgt
    12361 tcctagaaaa cgcccatttt ttttcttttt ttgaggcttt tgcagagtat ccatctggct
    12421 agtctgctca agtctagcat caactgccgc agatgcctga ctagcatttg ataccttagg
    12481 tgctgttaca ggagtcggtg ttacctttgg caagggcttt gtgctttcga catcatcaaa
    12541 gacaacctta cgctcacgac tgcggttata gctaagggct gtcatcaaat ccctgctcat
    12601 ctcaaaggtc gagcgataac ggtcacttag ctttttggca gtagcccgaa taacgacgtt
    12661 ttccaaggct tgaggcacat taggattttc atcaatgata gagggcagcg gcttttgaaa
    12721 atgctgcaaa gcaatcgtca cagcgctatc gccatcataa ggaatatgcc ctgttagcat
    12781 ttcaaagagc ataattccca tcgcgtaaat atcactttga atcgtcgctt tagaaccacg
    12841 cgcttgctca ggtgagaggt aatgcacact tcctagcata gaatttgtct gggttagact
    12901 ggtctctgca aaggcaacgg caatcccaaa atctgtaacc ttaacaacac ttgatttggt
    12961 caaaagaatg ttttgaggct ttaaatccct gtgaacaatt cctttttggt gggccagagt
    13021 catggcagaa agaacctctt ccatgattct caccacctca ttgttagata atggcgcatg
    13081 atcctgaatg tattttttca agtcagagcc atcaacatat tccattacta aaaattgctg
    13141 tccgtcttcc tcgcctatat cccgaatggc aacaatattg gggtgattta attcagccat
    13201 ggctcgcgct tctctttgaa aacgcgcaac agcaacctga tctgtttgat aattggtccg
    13261 caagacctta atggcaacgt cctcattatc cagaatcaaa tcgtttgcta aataaacatc
    13321 cgccatacca ccgcggccta tagattttag aatgcgataa cgaccagcaa atagcttgcc
    13381 aatctgaatc attctgcttc cccgctttcc ttatgcacca aagcaacggt gatgttgtct
    13441 aggcctcctc tttggtttgc caggtcaatc aaggcttgat ttttctcatc aaggctgatg
    13501 tcttgacata atatgtcaac aatctcctca ttagcaatca tattggttaa gccatcacta
    13561 ttaatcacta ggtaatcgcc cttttctaaa accttgacac ctaagtctgg ctctaccggt
    13621 gaagcttgac ctatagattg tgtgatgata tttttttgtg ggtggctagc agcctcctct
    13681 tcggtaatct gaccagcctt cactagggca ttaaccaagg aatgatcact ggttaaaaga
    13741 ctataatttc cctcatgaac caagccgata cgagaatcgc caatatgggc ataaatcgca
    13801 ttagaatcta ctagagcaac tgcctcaacg gttgttccca ttcccttata gtcttcagat
    13861 tgtcccaagt cgtagatacg ttggttctct gcttcgatgg ttgttaacaa ccaatccttg
    13921 atctgactaa gctcagtaaa atctgtctta acccactctc tacctaggtc tgtaacggtc
    13981 atctcactgg caatatttcc tgccctatga cctcccatac catctgctag gataacaagg
    14041 gtaatgcctt ttttattatc aaatttgttg ataaaatctt gattgtttga gcgcttttgc
    14101 ccaatatcgg tttttaatga aatcttcata taatcttttc tgactaggtc agtctcctcc
    14161 taaatactac aagactcgtc tgacttgccc aataaagaag ccatcagtct ggtattgctc
    14221 tggtgtaatc ataagacaac cgtccttgac aatatctgct tgtgcatgct tgagtgttac
    14281 ttgttcaaaa ttaggatgac gttgtaaaaa tttgtcaata acttggaaat tctcttcatc
    14341 aaaaatcgta caagtgctat aggttattat accacctttt cgcagcgttt gacaaacgct
    14401 agacaatatc tccagctgaa tttcctgcaa ttgctggaag tcctgccctt ccttgttgta
    14461 tttaatatct ggcttacgcc tgatgaggcc tataccagag cagggagcat caactaaaat
    14521 cttatcaaag ctgttcttcg caaaatgctt atgaacctct ctagcatcaa gcaccttagt
    14581 ttcaatccga tctgctaccc ctagacgctt agcattttca ttcactaagg ccagcttgtg
    14641 ctcatacaaa tcaagggcca ctactttgcc gctcgtcaaa taagaggcaa tgtgagctgt
    14701 tttccctccg ggtgcactac aagcatctaa aatcatttcc tgcccttgaa tatccagcgt
    14761 cggggcaact agctgactgg tctcatcttg gatcgtaatg tccccattga tgaaataact
    14821 gctggcagca aaattgccag ctctcttggt cagaccagtc ctagcaagta atgattgctc
    14881 tgatcctgtt gcctgcttga tctcatcaag ctttgtcaga tctgtgacac gtatgctggc
    14941 tctgcttctc acaaaaagac tttccatgat tgctacagct cgctcctcgc caaattggtc
    15001 gatcaatttt ttgactagcc agaccggtac tgagtaagca acagcatagt atttgttttt
    15061 tcgcttgatg ctcttgatat ctggtaaggg cttattggtc agctggcgca aaacggcatt
    15121 gaccagctta tctgctcctc tgccatgagc tctcgccttg gcaagattaa cagcgtcatt
    15181 aacaatagca tgagcaggca ccttgtctag gtaagccagc tggtaaaggc taagcatcaa
    15241 gagataataa acccatttat ccagcctgtc tcggtcctca atatagtgag ccagatacca
    15301 ttctagggtt atcttcctag agatagtccc gtaaacaatc tctgtgacta gagccttgtc
    15361 cttatcactt aaaaactgat tcgccagctg gtgcttcaag gcaaggttag aataggctcc
    15421 atgatcaaaa atatcctcaa cgataagcag cgcctgtcct ctagctgatt ttttccaatc
    15481 attcgccaag gacatcaccc acctctaggc ttctgccaat accatttaaa aagtcaacaa
    15541 taggcatctt tggcttgcct gctggttgaa cgagcgtcaa ggatagagcc ccctcacctg
    15601 ctgctacgac caatgctttt ttagttttag cgatgatttg cccagcagat ccagagcctt
    15661 cagccaattc agcctcataa attttgaagc gctgcccatc taataaggta tgagccaccg
    15721 gccaagggtt cattcctctg atatgattaa acacctctct tgctggcttt gaccagtcca
    15781 gtctttcttc ttctgctgaa agattgggag aaaaggtggc ttggctatgg tcttgaggaa
    15841 ctggctttag gtcaccagac aagtaatcag gcaaggtttt caataataaa tctcgtccta
    15901 gaatggccag cttatcaaac atggtaccaa cattatcagt atctaaaatt ggaaggcttg
    15961 cgcttgatat catatcccca gcgtccatct ccttaaccat ctccataatg gtaactccag
    16021 cttccttgtc accattgata atagcataat ggatcggagc gccaccacga tatttaggaa
    16081 gtaaggacgc gtgcacatta acagcaaatg tcaccgaatc caataagact gttggtaaaa
    16141 attgcccaaa ggctgccgtt acaatcccgt ctgctcctaa tgccatgata tctgctagct
    16201 cctgtgaacc agatagcttc tcaggctgaa aaacaggcag ctgatgtgca agcgccagct
    16261 ttttaacagg cgtcattgtg atgtcttttt tgcgaccaac cgcacgatca ggctgggtca
    16321 cgaccgctaa aatgtcatag gctggttttt ctagtaagcc ctgcaaaaca gttgctgaaa
    16381 attggggagt gcccataaaa attaatcttg tcatctatgt cctctatttt ctttcttttt
    16441 cattatagca tagcttggcg caaagtccgg taaagaacac ttacataaag ctctgtggct
    16501 cctgatcaat gataaccttt agctcgcgat tatcctgctc ttggctccaa tcaagaattt
    16561 gattcagggt agcttcaagc tgatcctcaa agcgatactt caaaataatc tgataatggt
    16621 aaagattgtg cgttcttgca attggctttg gcgttggccc taatattctg atctgatcag
    16681 acaagccctg cttcaatatg gtcagcagtt gataggcctt tttgaccacc tcttgctcac
    16741 tcttatgcga tagggtcaga cctactgtga aataataggg aggatagcct agctttcgtc
    16801 gaatccccat ttcataagcg taaaaggctt caaaatcctg ctttttggcc agttgaatcg
    16861 cgtaatgctc aggattgtag gtctgaatca ggacttcacc tggcttgtct gcacgtcctg
    16921 cacgtcctgc aacctgagtc agcaattgaa aggttcgctc cgatgcccta aaatcaggta
    16981 aatgcaagga agtatctgca tttaaaacac ctactagggt gacgttggga aaatccaacc
    17041 cctttgcaat catttgtgtc ccaagcagca catcagcatc accatttcca aactggctta
    17101 aaatagcctc atggcttcct tttttacgtg tcgtgtctac gtccattcgt aatattctag
    17161 cttccggcaa cacttgcttg agctcatcat aggctttttg cgtccctgtt ccataatagc
    17221 gtatgctttt gccttgacag ctagggcata gcttcggaat agccctttga aagccgcaat
    17281 agtgacaatt catggttttc gtatccatgt ggagggttaa ggaaatatca caatttggac
    17341 attgatcaac atagccacaa tctcgacaca tgataaagct agagtagcca cgcctgttga
    17401 gcatcaaaac agcctgctct tttctagcaa gacgctcttt gagtttatca atcaaataag
    17461 gggtgaagct gctaacctcc tgctgaccaa tataatctcg aaaatcaaca atctcaacct
    17521 gaggcatact ggcaagagga ttggctctct cagtcagctg gataaactga tacagtccct
    17581 tgctggctct agcgcgacta tcaatactag gggtcgctga gcccatcact aaggcagcct
    17641 tatggtgcct tgcacgaatg agagctacat ctctggcatg gtatctggga ttagattcct
    17701 gcttgtaggt ggcctcatgc tcctcatcaa taataatggc tccaatattt tctaaaggtg
    17761 aaaaaatagc agagcgagca ccgaccacca ctctagcctg ccctgtctta attttctgcc
    17821 attcgtcaaa tttttctcca tctgacaaac ctgaatgcat aatagcgacc tgtcttccaa
    17881 agcgggaaat aaatcgagag gtcatttgag gcgtgaggga gatttctggc actaagacaa
    17941 tagctgtctt tccttgctca agcacatgcg caatcacatg aagatagacc tctgtcttgc
    18001 cagagcctgt aataccttcc agtaaaaagg gcttagcctc tctgccaaca gccttcgtaa
    18061 tctggtcaac agcttgctgc tgctgctgat taagctttaa gagtggggct gccttgatgt
    18121 gattgaaata atcctcactg cgattgacac gtcgctcctc aagctcgatc agctggttgg
    18181 tcacaaaata gctaacaacc tctctagaat aatcctgata aagcttggct agcttatctt
    18241 tttgtggatt ggctaacaaa taagccttta aggcttggcg ctttttagcc cgatttgaaa
    18301 tcttatgctc ctgtaaggct aatctattga cctgatagta agtctcggtt ttgattgtct
    18361 ttttgtcctt ggctagataa gttgccctaa tcttaccaga ctgtatcagc ctaaggacac
    18421 gtccctcctg ctctggactt agcttagaat aaagcaagga atccccatta gagaaaacat
    18481 cagcaaggtc agccgcagct aagtcagctg tcggggtgag cagccgatcg taatgagaat
    18541 taagtaggct aggaagcatt gcctttaaga gggtgatttt gtaggaaaag actgtttgtc
    18601 gtaattgctc tgctaatgcc acctgctcct gatttaaaac aggctcagca tctaaaactg
    18661 accaaatagc cttcaattgc tgcgttgatt gactagaaaa gccaataaca aagccctgta
    18721 gcaacctatt gccattacca aaaggcacat gaacgcgaga accaatctta accagagata
    18781 atagctcatc tggaataaga taagaaaagg gcttatcggt ttgcatcaag ggaatatcaa
    18841 caatgacctg tgctatgtgt tgcattttga cttcctttct atcaagaaat ggacctgcaa
    18901 tatgaaaaaa actaagattg actcaacctt agattttttc tccctcttct tctttttctt
    18961 ttgcaatctg ctcttttatt ttacgctctt cttcttctct tgctaaacgc tctgcctcaa
    19021 accttgcacg aacagccgca cgcttagcag caggatccgg gtgaatcaca acattgcctg
    19081 actcaatctc ctctagtgcc tgaagtgttg atttgacaga cttaaaggac tgtgtcggtg
    19141 cagcacctgc ttctaattca tgagcacgct tggcctgtaa aataacaagt gaatattttg
    19201 atgggacttt atctaataaa gtatcaattg aaggttttaa catcatgggc tttactcttt
    19261 tctatttcta tcatctgaga gattttgttg ttttaatcat ttgatcatag cgaccaatca
    19321 cacgctcaac gcgaaaatgc tcggtctcaa taatacgctt gacacgctct gcagctaaag
    19381 gaacctcgtc gttgaccaca gcataatcat actctcgcat gagcgcaatc tcttccttag
    19441 ctctttcgat acgcttggca atcacctctt ggctgtctgt tccacgacca accaaacggt
    19501 cctgcaattc atctaagtct ggcggcgtta gaaaaatgaa gacaccatca ggcaccttag
    19561 ccttgacctg caaagcaccc tgtacctcaa tttccaaaaa gacatcaatg cccttatcaa
    19621 gggtttcgtt aacataggtt aagggagtgc catagtaatt gccgacatac tctgcatatt
    19681 ctagcatttg accatttttt attagctctt caaattcttc tcgtgtgcgg aagaaataat
    19741 caaccccatc aacttcacct ggtctctgtg gacgtgtcgt catcgaaaca gaatattcaa
    19801 atttatgatc tggcgttgaa aaaatctctt gtctcaccgt tccctttccg acacctgagg
    19861 ggccagagaa aacgattaac aaaccgcgtt cagacattgt gttctcctta ttgattgctt
    19921 tctaatagtt tatcaaaaag gctatcgttt ttcaagacaa ttatcagccc aatcctaaga
    19981 aagaaaagga agagatagac gccttctcaa agctagaggc taaactctgg cttttgaaaa
    20041 gcatacactc tttccttttt atttcgcata atctattgct cgcaactcac gaataacagt
    20101 taccttgata tttcctgggt aatccaagtt attttcaatc ttttctctta ccttgtgtga
    20161 gagaaccaca atctcgtcat cagaaatctt ttctggctga accatgatgc gaatctcacg
    20221 accggcttgg agggcaaagc tactttgaac accatcaaag cttgttgcga tttcttcaag
    20281 gtcacgaaga cgcttgatat agttttccac agattcattg cgggcacctg gacgagcaga
    20341 gctaagggca tcagcagcag ctaccagaac tgcaataacc gaatccggct cgacatcgcc
    20401 atgatggctg gctatggtgt tcacaacaac agggtgctcc ttgtacttgc gagcaaactc
    20461 cataccaatc tcaacgtggc ttccttcaac ctcacgatca atagccttgc ccatatcatg
    20521 caagaaacct gcgcgacgtg caagtgccac attttcacca agctcgccag ctaaaatacc
    20581 agctagctta ccaacctcga ctgagtggcg taaaacattt tgaccaaatg aggtacgaaa
    20641 ctgtaagcgc cccatgatct taatcaaatc cgggtggagg ttaggtgcac cgatctcata
    20701 ggcagcagcc tcaccatact cacgaatcct attgtccatc tcaagacgat ttttctcaac
    20761 caattcctcg atacgcgccg ggtgaatacg accatcagca atcaaggact ctagggtcat
    20821 acgagcaatc tctcgacgaa tagggtcaaa gcctgataaa acaaccactt ccggggtatc
    20881 gtcaatgatc acatcaatcc ctgtcagact ctctagagta cggatattgc gaccctctcg
    20941 accgataata cgccctttca tgttatcatc aggcaagtgc acacttgtaa tcgtctgctc
    21001 agtcacatac tcaccagcca tacgttgcat ggcctgtgct aacaggtcct tagcagtctt
    21061 gtctgtcctg tccttgatgt cacgctctgc atcacgaatg cgtgttgcga tctcatgcgt
    21121 cagcttgttt tcagtttcca tcaggataac ctcacgcgct tctgcaatgg tcatagcagc
    21181 aactcgttgg agctctgctc ttttgtcttc ctcaagtttt tcaacctgtg cctgtcgctc
    21241 atcaatgtgc ttagatttat cggtcagact ttgctctttg ctatctagta ctttttcttt
    21301 acttgataga ttttcatcct tacgatcaag agttagagca cgctctgcca agcgcgtctc
    21361 cagctgttta agctcttgtc tttcagattt aaattcctgt tcaatttctt cacgatactt
    21421 tcttgcctct tcctttgctt ctaaaagtaa ttctttacga cttgctttac tttcacgttg
    21481 tgctgtcttt ttgatatgag cggcatcggc ctttgccttg ccacgaatat caacagcatc
    21541 ctgttcagcg tttaaaagag tcaactctgc agcttccttc gcagacttga gtctaatcga
    21601 aataagtgca taacctaata ttacaccaat gaggccacag acaagtaacg ttatgatatt
    21661 aattaacatg tctttacctc aataatagtt tagttttcat taacagaaag ccatctctta
    21721 gtctatcata aaatgaagat ttagacaatt taaaatccac ctacattttt ctaaaatcta
    21781 gtgattttat gttatgatat tgataaaaat aaaaaggagt ttcttatgcc aaaagaagtt
    21841 attgttgaaa gctttgagct tgatcatact attgttaagg caccctatgt acggctaatc
    21901 tccgaggaat ttgggcccca gggagatgtg attacaaatt ttgatgttcg acttgttcag
    21961 cctaatcagg ctgccattga gactgccggt ttacatacca ttgagcattt attagccaag
    22021 ctcattcgtc aacgcattga tggaatgatt gattgctccc cctttggctg ccgcacaggc
    22081 tttcacctca tcatgtgggg caagcatagc tcaacagata ttgctaagat catcacgtcc
    22141 agcctagagg aaattgctac aagcatcact tgggaggacg ttcctggcac aaccattgaa
    22201 tcctgcggca attataagga tcacagcctt tttgctgcta aggaatgggc acagcttatt
    22261 ctcaagcaag ggatctctga tgatccattt aaccgccatg tcacctcata aaacgaaagc
    22321 ctctcttttc tgctaatgtg aaggaggctt ttaatgtatt caaaaaggtg ccaaaggcaa
    22381 ggctcaatgc ccttaccttt agcacctgtg ataactagag tatccagttc aggatcacac
    22441 cttgtcttct aagcattaat agtctaagtc ctctgcatgc cccttgccat ttccgacaaa
    22501 atagcctgtt ttgcaattca atgaaaagag gtaggtgcca tcaggcttaa acatgttgta
    22561 atagccattc ccattgataa tattgaccgg ctctaggata taatcattgc ctgaaatata
    22621 gccccttgct tgtgaggtag ccacaatacg ctcaagcaca cctggattaa aggcccaagc
    22681 agggtttcct gtatcagcaa tcatagcctg attgtagggc acacgagaca ggtcacgctg
    22741 caatattgaa gggtcatagc ctgtaatgcc atacattgga gccactggag ctggtacagc
    22801 aggaacctgc ggagctgcag ggcttgctgg taaggcagaa gcagctggag tgctagctgc
    22861 ttgggtagca gacctgcttg ctagctgctc acgacctgcc ttgatgcttg attgtagcaa
    22921 tgaatcaagt tttgcattac cagtggttag cgtatcacta gctaggtcat caaaattagc
    22981 atcagctttg acctcagctg caatcttttc accattgaca attgcagctg ttgtaaattt
    23041 cccattaacc gcctgaatag ctgttacttg ctttttcagc ccagtaacct tttccttagc
    23101 cttgtcataa taggctgtcc cttcaagcct ttttaaagca gtctccaaat tcggtaactg
    23161 atcaaaggcg ctatttttta gggttgtttt atcattatct gtgaaaaatg tcttgtaaag
    23221 atcttcaaaa gccttagcat tagcctttgt tttgttggtc tgattagctg ttgatgcttt
    23281 gctccttgct tttttagaaa cagtagcctt tgactgaggc ttatgcttag acagctgata
    23341 gatatggttg agggcaaagg ctgaggctac aagggttagc gtggctaaca aaatagcaaa
    23401 cagaggcttt ttctttttag acctacgact agcatagcta tctgataaaa tactctctac
    23461 ttctgcaggt cgctcgctaa ctgcgtcatc agctagctgc ccagtaaaat cactagcaga
    23521 atcagtagct gccgctgaag tgtcagctct agctgctaga ggctcaatga atgaggtctc
    23581 accggctggc ttctcctctg ttgaagcctc gtccactggc tcaacatcaa ctaagccggc
    23641 tttgctgagc tcctctcttt gttttttgat aaagttatcc agacttgctg tatctaactc
    23701 catatacttt gcatcaaact tttgtgatga cacttcgtta cgatgccgct taatatattt
    23761 gtctaaaaca ctatcatcct cggtaatccc tgcttttagc tctgagtcct tgcgtactgc
    23821 ctcaccgatt gtcatttttt tggcttcatg aagctccaaa ttttggcttt ctgcctctga
    23881 ttcaaatgct ttgctttttt ctgacacgtt ttttacctct ctatatcaga ttgcgcttta
    23941 ccctctctcc ataaaattga tacaaatcaa cccttagagt accattataa agcttacgtt
    24001 ttttatcagc tttttgacca tatttttgtt caaaatgatc atcactcgtc aaaataaact
    24061 tgctccaggt aactaatgga gcaaagacct gtaccatctc attatacaag atgtctactg
    24121 ctttgtcatc aagcaaacgc tctccataag gaggatttga aatgatgaca ccgtttatct
    24181 tgtctgtacg gaaatcctgc aagcgcattt gcttaaaggt aatgatatca gccaagccag
    24241 cctcctcagc atttctcttg gcaagctcaa ccatacgacc gtcaatatca aagcctgaaa
    24301 tatccagctc aatatcataa ttagcctctt tttcagcagc gtcacgaacc ttttgaacac
    24361 gatctttgtc cacccagctc cattcctcaa aggcaaagga gcgattaaag ccaggagcga
    24421 tattcattcc gatgagagcc gcctcgatac aaaaggtccc cgatccacag gtgggatcaa
    24481 ccaagggctt atccggaaac caattagaca gcttgaggat agctgctgcc atgttttcct
    24541 taataggagc tccccctttt tccacccggt agccacgctt aaataggctt gagccactag
    24601 tatcaatcat cagggtagcc tgatccttta agattgagac ctcaattttg aactcagccc
    24661 ccacctcttg aaggggaata tgctccggtc tatgaaaatg ctgctgcaat tttctgacaa
    24721 tggctttttt ggtaatggct tgaacacttg gctcgttgtg cagggttgac ctgacacact
    24781 tagcctttgc aataggaaac ctagcaccta agggcaaata atgctcccaa tccaaggcaa
    24841 atacgccctg aaacagctcc tcaaagcttc gtgctgggaa ctgacctaca ataatcttaa
    24901 tacggtcagc cgctcgcagc caaagatttg ctttagcaat agcttcaata tcgccttcaa
    24961 agaagacctt gccattatct actcggcagt caaatcccaa ggcccttaat tccttaccca
    25021 caacagcctc taggccagct gctgcagttg ctactaatgt aaattgttct ttcatatgac
    25081 tctttctatc ctaaccaaat aaaagctagc atatgctagc ttaacctatt atgcaatttt
    25141 ctataagcca tgttttgttc cagaaataac taggtattat ctccttcgat aatcatctgt
    25201 ctactgtttg tcaacagtca ggatagcttg ttcgtttcca actatcccat gcccctacca
    25261 aagtttgggt tgctagcttg aggggtttac cgcgttccac tttttacgtt tccataaaaa
    25321 cttcgtcact gtggcacttt cagagctact ctggcatatc aaggacttag ccttttcact
    25381 cgccgtaatg tgtcaaacac atccctaggc ttatttgttc gcctagcaca aacactacca
    25441 gcatcacagc cggtgctagc atggactttc ctcatagtat tgcaatacta cgcgattatc
    25501 caaaaattgc acatctacat tactcaataa tttgctttcc aaaaacctct ttttccagct
    25561 tgctaatgcg ctttagcatg tcaaaattgg tggctgactg tgctactctg gttggctgtg
    25621 ataccgcctg agagctgcct gctaaaggat cacgcacctg agccttagcc ttttttaagg
    25681 cttcattttc agcctttagg gcctcgatct gagcattgaa atactcataa tccttgatga
    25741 cgttatcaag gaattcgtcg acctccttct tatcaaagcc acgcatactg gtcttaaatt
    25801 cttgctcaaa aatgtccttt ggactataaa ttatacctgt cattctatac tctccaaacg
    25861 gtcaatcttt ttcaaatatc aaactttgat atcactactt atgatacaga aaaataaatt
    25921 aaaaagcaag tatttaaata ccagtgattt ttaaatatca ctagctactc atctgcaatg
    25981 tcatttaaac gctcaaagtt taggaaagaa agggggtaac agggctgctc cttcatagct
    26041 gctaccaaat agcttaggcg cgtttcgtgc tcactatcat aaaaaagata ggctccgtct
    26101 gtattgtgaa tcaaaaagtg atggtagctc tttagctgtt tagggctttc atagctggga
    26161 tagctatatt tgacaaaatc agtctcccga aattgctgca gctgctgctg attgcgatca
    26221 ttccaagtgc tgccatgcgt ttcaaaggca aaaatagtcg ctgtctttaa ggggtaggtc
    26281 tttttgaggt cattagctac ctctaaagcc cactgctcaa accctaaatt cccagtaaaa
    26341 ataaaccagt ctaccccctc ctcaagataa gcaatcagat ctctttctat cgcttttttg
    26401 ataatggcaa ctcttttatc cttttcacta aagatgccca gctcaaaact tcgatagcct
    26461 gttacgagaa ttgcagtcat tagatgttat cctttcaaaa atatgttata atgtgaatgc
    26521 ttaaattatt attaagtcat gatgttagga gaacaatggt taactaccct cataatccta
    26581 ttcgccaaaa ggtgacccct cttcaaaagc agcaaaagca caagcaagta gactttgcta
    26641 atcgtggtat gtcctttgaa gcatccatta atgcaaccaa cgcttattac ttggccaagg
    26701 gcattgctgt cattcataaa aagccaactc cgatacagat tgtcaaggta gactatccaa
    26761 gacgtagtcg agccaagatt gttgaggctt attttaagca ggcttcaacg accgactatt
    26821 ctggtatcta caaagggcat tatattgatt ttgaagctaa ggaaacaaga caaaaaacag
    26881 ctatgccaat gaaaaacttt cacgcgcatc agattgagca catggctgct gttttaaagc
    26941 aaaaaggcat ttgctttgtc ctccttcact ttgcgacact aaaggaaacc tattatctac
    27001 ctgccaaagc actcattgat ttttatcaga ttgatagggg caacaaatca atgccacttg
    27061 attatatcag aaaaaacggc tttgaggtca agctgggagc atttccacag gttccttatt
    27121 tagatattat agaacaaaaa tttttaggcg gtgattacaa ttaacaatcc aaaaatcctt
    27181 aaattcctga agtatacatt aggtgctatc cttagcctta tcattgtgac aattacctta
    27241 ggtggccttt tgtttgctta ctatatcagc agtgccccta agctttctga ggcccagctc
    27301 aaatcgacca attccagtct tgtttatgac ggtaataatc atttgattgc tgacttgggc
    27361 tctgaaaagc gtgaaaatgt tacagctgac agcattccta ttaatctggt caatgctatt
    27421 atttctatag aagacaaacg cttttttaat catcgggggg ttgatctcta tcgtatctta
    27481 ggtgcagcct ttcacaattt aacaagcaaa acaacccaag gggggtctac acttgatcag
    27541 cagctgatta agctagccta cttctcgaca aacgagtctg accagacctt gaagcgaaaa
    27601 gctcaggagg tttggctggc ccttcaaatg gagcgaaaat ataccaagca agaaatcctg
    27661 accttctaca tcaacaaggt ttatatggga aatggtaatt atggtatgct gacagcagcc
    27721 aaggcttatt atggcaagga tttgaaagat ttgtcctatg ctcagctagc cttgctggca
    27781 gggattccac aggccccaag ccagtatgac ccctacacac agcctgagac agctcaaagc
    27841 cgccgaaata ttgtccttca gcaaatgtat gctgaaaaga acattaccaa ggctgagtac
    27901 gaagcagcta tcgccacacc tatatcagaa ggcctacagc ctctccagca acgcgccagc
    27961 tatccaaaat atatggataa ttacttaaaa caggtgatcg agcaggtaaa ggctgagacc
    28021 aacaaggata tctttacctc tggtctaaag gtttacacaa acatcattcc agaggctcaa
    28081 aaaaaacttt atgacattta caattctgag gactatgtgt attaccctga tgctgacttt
    28141 caggttgcct caaccgttat tgatgtcaca aatggacacg ttatcgccca attaggagga
    28201 cgcaatcagg ataccaacgt ttcctttgga accaatcagg ctgtcttaac cgatcgtgac
    28261 tggggatcca ccatgaagcc gatcacagac tatggacctg ccattgagtc cggtgcttac
    28321 aattctacag ctcaaacaac taacgactct gtctactatt ggccggggac acacactcag
    28381 ctctataact gggaccggag atactatggt tggatgacca ttcaagctgc tctcatgcaa
    28441 tcacgaaacg tccctgcagt tagggctcta gaggcggcag gtcttagcta tgcacagtcc
    28501 ttcctcagtg atctaggcat taattatcca gagatgcatt attcaaacgc catctcaagt
    28561 aacaatagca gttctgattc aaaatacggt gcaagcagtg aaaaaatggc tgctgcctat
    28621 gcagcttttg ccaacggtgg actctattac aagccacaat acgtcaataa aattgaattc
    28681 agcgatggga ccagcaaggt catcgaaaat aagggcaagc gtgccatgaa agaaacaaca
    28741 gcctatatga tgactgatat gctaaaaacg gtactaacct acggtacagg tactgctgct
    28801 gctatcccag gagttgcaca ggctggtaaa actggtacct caaactatac cgatgaggag
    28861 ctggcacaaa ttgttgagac acatggacta tctcctgatt acgtgggaac aatggcgcca
    28921 gatgaaaact ttgtcggcta caccaaccga tacgctatgg cggtttggac tggttataaa
    28981 aaccgtatga cgccaattta tggctacagc ctagaaattg cttctcatgt ttatcgcaac
    29041 atgatcagct atctcaccgg cggctacagc gacgattgga ccatgccaag tgggctctat
    29101 cgtagcggcg gcttcctcta cctaagtggt acctatacaa acagtagcga ttatacaagc
    29161 tctgtctaca acaacctcta tggtaataac agctcagctt caagccaatc ctcagatgag
    29221 gatacaactg aagacagcca ctcagaagca aacgacagca caacgtcatc atcagagcag
    29281 caatcaagct ccaccgatga taagaaaacc aactgataac aaaaaactgg ttcaaatgtt
    29341 ctgaaccagt tttttcaatt atttggctaa ggcacccatc ggatcccaag gggcaagtac
    29401 ctgtggttct gcctcatagg ctgctaattc atcagctgtt agtaggtcct tgcgaacaac
    29461 aatctggtaa gtatactcgt ccatccaagc atcagaagca acaaagtatc ctttgtcacc
    29521 aaccttgtct ccccaagaat tttcaacctt ccatttgata ggcttaccag tatcatctaa
    29581 atcaacacct gtcaaaacca tagcatgtgt cattaagctt tcgctgtaat caaggcgacc
    29641 agccttgtct tggctcaact gaatatccat acctgcctga aaatcatagg tattaagggc
    29701 tagaatcccc ttttgacgat ctgatacctg accaacgtct gaaccaaacc aaacggactc
    29761 tccagcctgc atttgcttaa tagcaagctc cttgaagcgc tccatatcaa gattaaggta
    29821 gcgcacctca ggactgccaa caacattacc aagcatatca accgtataag atttgccata
    29881 aggcttatca gctgttgggg cgttgataac agacacataa tcagacagct ttagaccaac
    29941 atatttttca taaaatgcct gtggtgtgat gcccttatca gcatgatagt gattatcctt
    30001 atcacgataa gcaaaatcaa attgacgagg tggcaaacca agattcatgg ctaagaaatt
    30061 aaagatttcc tgaagtagct cttctttttt agcctgtact gcctgatgat cagcaccagc
    30121 actgatcaca tctcgaagaa tctgagcgtc ctgacgcaag agcttattga ggtattgatt
    30181 tagctcacga ctattgcttg atgacacaga ctctgggtag actgattttg gcacaacacc
    30241 gtatttttca aacagggcta caaccatgtc ccactgacca ccgtcttgct gcggaacgtc
    30301 caaaagaaac ttaaccctac ggctagtcaa ggcttgatca gcagttgcaa tcacctgttc
    30361 cataaaccag tttgattttt cgtatttgtc ccagaaaaag gtgtgtgctt gtgacaactc
    30421 aaaatcttct aatttaaatt ctgaaataag cttatggcga aaggtgttta aggctgcaaa
    30481 catccagcaa cgacctgaag ccttttgatt agagacctta tcctttgtca agtcaatgga
    30541 aaagacaaaa tcattgtcga tctcactttg tcttgtctcc aaggatttaa gcaagccatt
    30601 gtgagtgatg gcattttcaa gagctaaata tttagcatta gcttcataat tagcatatag
    30661 ctgttctgta aatgtctctg ttaatactga catcattttc ctccaaagat aataaataac
    30721 aacacctaaa aataaagttg acagaaaaat ccataaatac tgtcaatttc attttcaagg
    30781 attacttcta ttatagacct tatttgatat tcttcaagta aaaaaattag gctaacttaa
    30841 ttttttaaag ctaagcagca gctttccaat aaccagacaa aaagccatct caaaagacga
    30901 caaaacctgc tggactttga gcacctaaac atgtcatatg tccacctcag catgaactca
    30961 aagaagctag ctgtgtctgg ctatgacttc agtttaatca ttagcttgcc ttagccacaa
    31021 aaagaatcgt ctccactgta gcaaaagtgc ttgatataac accatcggct aagtcaaggg
    31081 gcccctgata gttaactgaa acatatggca aagctaaaac caaagacttc ttctccttaa
    31141 agcctctggt ttttagttag ctgagcattc tcctttatct tggctgcttt aagataggga
    31201 caaatcaaca actaccccaa tcccatttac aaaaaagccc taagtcagag ccttcatagg
    31261 gctaagggtg agggaagctc ttaggcaaca gctactggat ttatgcctaa tagaagctcc
    31321 tgtccctcct cacctattta aaatagcatt ggtttatcta tagcctgtgt aggtttgagg
    31381 atcacttcca aaagtcatca aaaatagtaa ttggcagatg gcgcttgtgc tgccctttat
    31441 gccaccagtc ttcaatcctt gcctgagctt cagcggaaat cgtatgcccc tctaagtaat
    31501 catctatctc ttgataagta acacctaatg ctacctcatc tgcaagtcct ggcttcttat
    31561 cctctagatc tgctgttggc accttctcat agaggctggg gtcagccttt agcaccttta
    31621 acaaggcctt accctgccgc ttagtcaagc gaaaaagggg tagaatatcc gctccgccat
    31681 caccaaactt agtgaaaaag cccgtaacat tttcggcggc atgatctgtc ccaatgacag
    31741 caccagctgt ttgaccagcg atagcatact gactaatcat acgctgacgt gccttaatgt
    31801 ttcccttatt aaagtcagaa atctcaagcc ctgccgcctc taaggctctt agctgaccat
    31861 caacagcctc tttaatatta accgtcaagg cttgatcagg ttgaataaat gctaaggctt
    31921 tttgtgcatc tgcctcatct gcctgaacac catagggcaa gcggacagcg ataaattggt
    31981 actgctcatc acctgtttca gcgcgcagct cttcaatcgc catctgagct agctttccgg
    32041 ctaagctgga atcctgacca ccagaaatcc ctaagacata agtctttaaa aaagggtgct
    32101 ttaacaaata agcctttaaa aaatcaaccg actggcgaat ctcctgctta ggatcaatta
    32161 ctgctttgac ctcaagctga cgaatgatat cctcttgtaa tgtcatatca aatcactcct
    32221 tttacaggct tccttgcgga ttttgtcaat aagatgcatc ttattttgcc aaacatcaag
    32281 cgcaagatcc acagggtaat gctgcggatt caagacacgc ttatattcgt cccaaagctt
    32341 atcaaattcc tttctagcat aagccttgat gtcttttaag cttggcagct gataaacgag
    32401 ctttccttta tcaaaaatat ctactagcaa aggaacagca tcaaaatctc tgacggtttt
    32461 attaatgtag gtataagtcg ggtggaacat gtgaatttcc tctaggtcat tgacattaac
    32521 acctgtaaag gtgatgtaat cgccttctga cttgcccttt tcgcggctgg taattcgcca
    32581 aacctgcttt ttacctggtg ttgatacctt ttctgcatta tttgatagct tgatagtatc
    32641 gcgcatggta ccatctgcct gctctatcga aacaatctta taaaccgctc ccagagctgg
    32701 ttgatcatag gctgtaatca attttgttcc aacaccccaa acgtcaattt tagctttttg
    32761 cattttcagg ttgagaattg tattttcatc taaatcattg gaagcgtaaa tcttagcctc
    32821 tgtgaagccg gcagcatcca gctgctggcg taccctttta gataggtaag caaggtcacc
    32881 agaatccaga cgaacaccca agaaattaat cttatcacct aattccttgg ccacacgaat
    32941 agctgttggg acacctaccc tcaaggtatc ataggtatca accaagaaaa tacaatcctt
    33001 gtgcacactg gcataggcct tgaaagcatc ataatcatta ccataggcct gtaccagagc
    33061 atgtgcatgc gtgccagaca caggaatgtc aaaacgcttt ccggcacgaa cgttactagt
    33121 tgcgtctgct ccgccaataa tggcagcacg tgtcccccaa acagcagcgt ccatctcctg
    33181 agcgcggcgt gtcccaaact ctaaaagtgg ctcatcttca ataacagagc gaatacgagc
    33241 tgcctttgta gcaatcaagg tttggaaatt cacgatattc aaaagagctg tttctactag
    33301 ctgacattga cctaaaggtc cctcaacctg aacaataggc tcattggcaa agaccaagtc
    33361 tccctcttgt gctgagcgaa tcgttagctc taaacgaagc tctctgagat aggtcaaaaa
    33421 agcagggctg tagcctagct ccttcaaata agccaaatcg gtctcagaaa aggtcaattg
    33481 ctcaaggtat tctacgattc gttgtagacc agcaaaaact gcatagccat tgttaaaagg
    33541 ctctctacga aaataaacct caaagacagc attacgatta tgaatgccct gctcaaaata
    33601 aacctgcatc atatttaatt gatataaatc agtatgaagg gttaagctat catctctgta
    33661 catataagta actccttaac ataattgtta ttattatacc atatttttgg catagacctg
    33721 taagattcaa ctaaaatcct ctgctcaagc tttctaaaaa agaagccttg agctgctatt
    33781 aagcctgaca tattttttgc cagtaccttc ctaaaaagtc tatagcacaa gggcttatgg
    33841 ctttttaaca aaagcagttt cagttgatag cattcataaa aaaagattga agaaattgac
    33901 caaaatagcc cctttcttca atctatttaa ctcacacctt agccttttaa cgctttttta
    33961 cacttgagct gactgtagca gccaaagact agaatccaaa tgctagcacc aattgccccg
    34021 atataggtgg acttctgtaa aaacagtgaa ataaaaacaa aggcaaaaaa ggctagggtc
    34081 aatggtgttg ttagctgata acttggcatc aaataaccat ctggcataaa gtcactggac
    34141 tgacgatatt tccaatgcgc aagcatggtc aaagcataaa tcgcaatata aacaccagat
    34201 gatgaggccg taatcagcga aaaggcatct gcaacaccgg gcaggatatt aatcaaggcc
    34261 gacaccccaa cagcaacagc agaagcaata atagccctac ttggtacccc ttgacgagat
    34321 agggtgttaa tcctcaaggc tttagtaaga gcatttgggg tctcattagc gatttgatac
    34381 aaatgccgac ctgtcgaata cagggtcgaa tttagggctg atgctgctga tgttaagacc
    34441 acaaaattaa ttaaagcagc agcccattta atcccaatca gcttaaagac catcacaaag
    34501 ggagactcgt ccgtaggcaa ctgataccaa ggcacaatcg ccataataga caccaaagca
    34561 ccaacgtaaa aaatgacaat ccgcatcgga atctcttgga tggccttggg caagaccttt
    34621 ctaggatttg cggtctctga ggttgtaata ccaacaaatt cgatggcctg ataggcaaag
    34681 aaaaccatct gaaaggccat gaaaaatttc aacttcccat tcggaaatag tgaaaaatga
    34741 tccacaatat tggcaaggct ggcatgaccg acatgcgttt caaagcccgt tagaaccata
    34801 aaaacggctg ttgcaatcaa ggctaaaatc gcaacaatct taatcatggc aaaccaaaat
    34861 tcagtctctc caaagacccg cacagcaatt aaattgatgg agctaagcaa caccaaaaaa
    34921 acgagctgaa tcagccaaga tggccaagca ggaaaccaaa actgaacata ggaggcgaca
    34981 gctgtaatct ctgccatgcc aataaagatc agggaaatcc agtaagaaag cccagaaaaa
    35041 tagccccagc ctggcccaat atattttgta atgaaattga taaaggtatg ctgatccgga
    35101 tcatagtata gcatctcacc aatagcccgc atcatcaaaa acataaagac acctgtaatc
    35161 atgtaaacaa agataataga cggacccgtt aaggcaatag aacgaccagc tcctagaaag
    35221 agacctgttc caatagtgcc tgctatcgca atgagctgaa catgtcggtt ttgcagcccc
    35281 cttaccatgc cattctcaag ttctttagtg cttttagctt cttttgtaga catttgactc
    35341 tccattcaat taaaaaaaca ccactattat atctgttttt cagaaaatgt tcaactttct
    35401 ctaaggcttg caaactaaaa aggccaacca agccttttta gcgttaacct ttttaagatg
    35461 ataggctttc aatgtaatgg tagacgcctt gaccggcaat ggcaccatct ccaactgctg
    35521 ttgtgatctg acgcagctgc ttttgacgaa catcaccgac agcaaaaata ccaggaatac
    35581 ttgtcttcat ttgatcgtct gtcacaatcc agccctcttg attggtaatg cctagctcag
    35641 ataccatttg agtaaccgga atcaagccga catagataaa gacaccacca aagtcatggc
    35701 tagtcacttg acctgttttg acattttcaa tcacaacatt agagacctta atatcgtttc
    35761 cttgaatctc cttgacaaca gaatcccaga taaaatcaag cttttcgttg gcaaaagcac
    35821 gctcctgcaa gatcttttgg gcacgcagct gatcacgacg atgcacaatc gttactttct
    35881 tagcgaactg ggtcaggtag atggcttcct caactgctga atctcctcct cctacaacta
    35941 ataactcctg attgcgaaag aaagcaccat cacagaccgc acaataagaa acacctcgac
    36001 tggtgtactc ctcttctcca gcaacaccta aaagacgatg ctttgctcct gtcgcgacaa
    36061 tcactgtttt agtatcgtag tgcgtatctt ctgtgtacac acgcttataa tcaccacaat
    36121 cctcaaccct ttgaacaatg ccataaatgt tttcaacctt aaatttttca agcggctcat
    36181 acatctttaa cgatagctct ggtcctgaaa tgtgatcata gccaggataa ttttcaatat
    36241 ctgatgtgtt attcatttga ccgccaggtg ccccctgctc aataatgcca actcgtaggt
    36301 tactacgtgc tgcatataaa gcagctgtca taccagcagg tcctgatcca ataatgagtg
    36361 tatcgtacat gggttaactc ctcttaatag tcttgtcatc attttaacaa tagctacatc
    36421 gtattgcaat tatttcgcct tcaataccac cagaatgctc ataaaggcaa aggacaaaat
    36481 cggaatcgtc aaaatagcaa ccataatcat ctcatataaa aatgcctgtc tctggagaat
    36541 ggttttatcc tttttggtca cagcacgcca taaaatccac aaaagacaaa gcatgaccat
    36601 cgtaatagct gctaacaaca gaccttccaa ataaaagcga aaaatttcta ctaacatctt
    36661 tatctacctg attaccataa ccttttttca tggcagctta gcttttaagc acatacaaga
    36721 aaagcctagc ctacctagac ctttttatta tatcaaaagc cggcttttaa atatacgttt
    36781 ttgcatagtt tgcaaaaaat tcctttgttc ttgcttcctt agggtgtcta aagatctgct
    36841 caggagctcc ctcttcaaga attttcccct tgtctaaaaa aagcacccta tctgcaacct
    36901 gataaacaaa agccatatca tgactcacta aaatcatcgt ttgacctgcc ttggcagcat
    36961 caataataga ccgttcaacc tctccaacca gctcaggatc caaggctgag gtaggctcat
    37021 ctaataatag cacatctggc ttcatggcta aagcacgcgc aatagcaacc ctttgctttt
    37081 gaccgccaga taaatgacga gggtaatggt tttcacgatc agacaagcca accttagcta
    37141 attctgctct agctatgtct gttgcttctt ggtcagacag ttttttaact atttttaatc
    37201 cttccttgac attgtcaagc gctgtgcggc gttcaaagag gttaaattgc tgaaagacca
    37261 tcgctaattt tcgtctaagc gttagaatgt cttcttttgt gatgtgttca aagtcaactg
    37321 caaagtcatc aatcgtaata cttcctgtat ctggctgttc aagataattc atgcttctaa
    37381 ggaaggttga ttttcctgca cctgatgcac caaccagagc tataacctgc cctttttcaa
    37441 tcgtcaccgt taaatcgtct aagatctttt gtccagagaa ggacttggtt aaatgagtta
    37501 ccttaatcat tagcgcaatt ctcctatctt gctattattt gttgggattg gtgctttgat
    37561 agccatgtta tattcaatta ggcgaccagc ctgttctatc aaaatactaa tgccccaata
    37621 aactaaggca actgagatgt aacgttcaaa ataacgataa tctgctcccc ctagaatctg
    37681 tgcctgtgca aacatttcaa cgatacctgc attgaaggcc agagaggttc cctttgtcag
    37741 gcctatcaac ccattaatca aggtcggtgt tgccacaaca gcggcatttg gaatgataac
    37801 tcggcgataa acctgagcag aggtcattcc taggctctta gcagcctcaa tttcgcctgt
    37861 gtgaacagat tgaatcgcag ctctaatggt ttcactcgta taagcagctt cattgaaggc
    37921 aaaggcggta atcgcaaaga tagaagccgg aatagcgttg atattccaat caaagccata
    37981 gcgttgattt aagaatttca gaaaaagagg aataccatag tagctcagca ttagctgaac
    38041 caatatgggg gttccacgca aaaagctaac aaaaaccgct tgaatcggat aaagaatgcg
    38101 aaccctgttg attttgacaa tggcaaaaac caaggccaaa aaaagaccca aggcagcacc
    38161 agctatcgtc aaaccaagtg tgattggcag acgcctgata atatctggaa tggcatcaaa
    38221 aacagcatgc cagctaaaca gcttcccttc tgggatcaac gagatgagct tgtcatacca
    38281 agcccaccca cttgttaaaa acgtagatgt catgtatcgc ccctttatac tggtttgtct
    38341 caatattttc attttaacat tcttgagatg tcatgtaaaa tagtaaatcc gcatgataat
    38401 gataagaaaa gcctatcgca gaggatagga ctcaaacaaa ggaaaaaaac tctttgaaat
    38461 accgttaaca gtagcctctt ggagctacca agcttgaact tgagccgaac tctcaaagcc
    38521 tccaagtggc taattctcaa agaatatagc cactggtaca agactaacaa tcagctacta
    38581 ggccaaaaag gtcaaaagct tggctagctg gcacagctaa ctgcctcaaa ggctaggtca
    38641 acgaaagatt gaagcctgcc cagggcttga gggcttttag ccctgtcaat taattgacct
    38701 tggagataaa gtctcctccc aaaaatgctt ggctgagctt tctgagctga cctgattttt
    38761 taagcttagc cagccttttg ttgacaaagc tctgtagagc cttacccttt tgatcattgg
    38821 caaacacata atattccaag ccatccttag cagtatcagc ctgctccttg agctttgtca
    38881 catgcacatc aaagccttgc tcctcagcta cggttgttag agaaatagcg tcatagaaaa
    38941 gaaagtccag ttgaccattt tccagcagct gcagcctttg agtaaatggg gttgactcag
    39001 aagcataggt aaggtgaata ggcttttggt caggatggga ttggttccat ttttcaagga
    39061 taagcatgta attggagcca gctattcctt gggttttctt tccagaaaga tcagctaagc
    39121 ttttatactg ctgcttaccc tttgttgcca gagcataatg cgaggccgaa atagggcttg
    39181 aaaacaaata cttttcagct ctttccttac tatagccaaa attattggcc ccaatctgat
    39241 aacgacctgc atcaatacca gccaggatcg atggaaaagg aaccacctct atgcttaacc
    39301 gatacttttt ggagccttta aaaacccttt ttagaacctc aatatcatag cctgtaacgc
    39361 tatgcttctt cctataggta aagggcttag tggcagcatc tgttgctact ctgatcacct
    39421 ctttttgacg agctgtgacc tcatggctag tcacgactgc caagagtcct agacttgcta
    39481 gcaaaaaaaa gagtgctcgc tgtaattgtt ttgtcatacc atactcctat ctcttataca
    39541 gtagccattt taacaaaaaa tgataaattt gaataatatc atttctctat caaggcaata
    39601 agaaaatagt atcaaacaag caattaaaac agcacattct tcatttacct gatcatggat
    39661 taaccacaac agacaagctt tagctattag caggctgcct aagccaaaat caacacctca
    39721 agctttcaac tgactgatgt aaaagctagt agtcacctct acaagaagaa aaagaactgt
    39781 ttgtgtcatt caaccagtag cacccttctt aactggtcat tcctatccag ctctactact
    39841 aggctgtcag ttaacgatca gaaaaaaagt tgacctatct gccttatgaa gcctagaaaa
    39901 ctagctttca ttctgtttaa cattagaaaa cgagtaaata gtttaaaata aatttttatt
    39961 attaaacttt aactgttgct atattaatct ttttacatta taattaagta taaggaggtt
    40021 ttctatgaaa aaggcaatag tatcggttac tttgttaaca gtagctgttt taagcttatc
    40081 aacaagattt atctactcca ctgattattc tgatttaaat cataaggaga tggcacgtct
    40141 tatccagtca agaaaacaac cagtaattaa gtatcatgac aatgtaacca ttaataaaat
    40201 gattacttac ctagctcagg ctaaaagaga aggcattctg acagagacct tcctcatgaa
    40261 ttatattttc gctggagagg gtgagtacct gactaaaaat tcaaggatta ttgccgatcc
    40321 tgacggaggg tattggagta tcctagaagg ttatgaggga gatggcggtg ttaagactgg
    40381 tattgacggc gtctcagagc tcaatatctt tagtccagaa tctaccagca tcggagagct
    40441 tcaagaagcg gtgctagcct ggtatgaggc taataagtaa ccgcagctta gttaaccgac
    40501 tgcttcatat aatagctaat attagctaat cataggcctt ataggcattg aaatggtcag
    40561 acccatgctc aatgcttata aggtttttta gtgcttacca tctaaccaaa accatagcct
    40621 tcagagagac attgagctga acaagcaaaa aagaggagca agctcctcct caaacattaa
    40681 tacaccttaa tctacactcc cacagaggaa gtaatttaag gctggtgtgt caaagcgtat
    40741 caacccgtta atttcaatca ctattctgac agccaaaggt gcggctttag ttgttaatag
    40801 ctggttttag ttgccacgct tcaaagatag ttgctgtaac aattgaagta ggttcgacaa
    40861 tttcaaatgt aacaatactt ttatcacacc ttttgcggga gcgtagattg aaatccttgc
    40921 acgcaacgac aggaccattt gacatgggac actgaacaga gttgaagcct ttaaaaacaa
    40981 tccctaaaca gctttgggac ctaatcacag ttccttgact cagctctgtc aaggattctg
    41041 ttcatatcag cttagaatga tcgctaaaaa ctttttgatc taatttttct tgaacggatg
    41101 atctttacca agcacctgtc ttaaaagctt tgctttctgg actgacgctc tgctcgtccc
    41161 ttggcacgtt tttctgctcg tcgctgcttg cgccgctttt catcaactgc ccattgaatt
    41221 ttctttttat agcccggttt aatttttttc ttttttttct taaccaggcc aatcatttca
    41281 gtgtctaatt tctgataagc tttttcacga ttctggcgac gatcacgatc gtaagtatcc
    41341 tgaaactcac cattttttaa aacctttggt ataaaggtaa tgcctagctt ttccagctcc
    41401 ttgatatcag aatcatcact tggctgataa aaggtaatgg ctgtccctgg caggccgttt
    41461 ctacctgtcc gccccacacg atgcacaaaa aaggataggt cttgaggaat ggcgtcgtta
    41521 atcacatgac taaccccctc aatatcaata ccacgcgccg ccaaatccgt tgccacaatg
    41581 tattcaaatg ccaggttttt gacttgattc atgatacgct tgcgctctct aggaggaata
    41641 cctccatgaa gcttggctgc cttcatacca ttagctgcta aaaaggcatg taagtcatca
    41701 gctctctcct tggtattgac aaaaagcatg gccagataag gctggatagc ctttagagtc
    41761 gccaaaattt gctcattttt atcgcgtccc ttggttgata acagccagtt gtcaatcgta
    41821 tctgcaataa cggtttctgt cttgatctgt tcaatgacag gattggtcaa atacttcctt
    41881 aaaaagggct gtagcttttg tggaatggtt gctgaaaata caagtatttg gatagtcttt
    41941 ggcagtgctg aagcaatctt atccacagtg cttaaaaagc ccatatccat tgtcatatca
    42001 gcctcatcaa caacaaaggt agaggcctta tgaatggcta aatctcctga cttgactaga
    42061 tcatagatac gacctggcgt tccaatgaca agctggggct gactaagctt taacttgtca
    42121 agctgacgct gcttgtctgt ccctccaacg taattagcaa tacgaatctc ctgcttagaa
    42181 tgcttagcaa tttgcctgct ggcctcaaaa atctgtgttg ctagttcccg gctaggtgct
    42241 gtaatcacag cttgaacctc ttctttttcc tccttgagct tttcaaaaat aggcagcaaa
    42301 aaggtatgcg tctttcctga gcctgtcttt gactcaccca ctaagtctcg tcctgtactg
    42361 acaatcggga taagacgctg ctgaacctct gttggctcta caaagccaag ctcatctagg
    42421 gcctcttgaa tataatgctt aaagtgataa tcgtgaaatg acattattta cctcgttttc
    42481 tttctgataa tactattagt gcttgagatg agcaaaaggc ggtgcctcaa gcactgcccc
    42541 agccgcttac aaataaagaa tcgctaaaac aatgagactg gctacaagac caagagccca
    42601 taggaaggca tcaaccttcc attcagacca cttggctgct ttaccggaca agccgcctaa
    42661 ttccagatga tgatgaaaag gagtcatcct aaaaatccga cggccttcac catatttttt
    42721 cttggtgtat ttaaagtaag taacctgaag catgactgag cttgtctcaa gaacatagac
    42781 aatcccaata accagcaagg tccattcctg acgaagcgca atagaaatcg ctgctagcat
    42841 tgctcctaag gctaagcttc caacatcacc cataaaaatt ttggccggct tatggttaaa
    42901 caagaaaaag gccagcaagg caccaaccat gatacctatc aagagcaaaa catcaaattg
    42961 tccctgagca taagcgataa caccataggc cagcaggcta atcacaacag ataccgaggc
    43021 cagaccatca ataccgtctg tcaggttgac cgcatttgaa aagccaacca cccaaaaaag
    43081 aacaaagcat aggtataaaa agcccaaatg ccaatgataa ccaaagacat taatcgcatc
    43141 aataccactt ggcatgacgt gtatcacata aaagaccagg cctccaacaa tctgaaacgt
    43201 gaatttttgc ttggcagtaa ggccttcatt aacctgcttg aagatcttta agaaatcatc
    43261 taaaaagcct atgatcccgt aaatcaatac aatcaacaag atccccgaaa tcaagcctag
    43321 gctttgtcca tctcgaaaat agactaaagc aaacacaaag gataagcttg tagcaacaag
    43381 aagaaaaact gttcctccca ttgtaggtgt tccagcctta gccaaatgct gcttaacgtc
    43441 ctcatgcatc tgctgccccc caattttttt caactggtaa agccttataa agtgaggcat
    43501 ggcaagggca gtcacagcaa aggctatcag acctgctaga atggttaaaa acatgttaat
    43561 ctcctaaagt tatggtaatt tttttgactt ttttgagcgc ttttccgaca tcaacgctct
    43621 gtttaacgac acgtcccgag cttgatccct tgtacttgat atcaatgcca gtccatttag
    43681 caaaggtagc cacattagcc ttagtccagc cgtacatatc aggcatctca tcaaaatgat
    43741 ttgataaaat cagaagctgt tggttagcag ctagattggt ccctgccttt ttagatacct
    43801 ttttaatctt gctgccattg ccaaggacaa tagggtgaac cagatttctg cgtagctcat
    43861 cagctgattt tcctgtatct tggccaacaa tatcaggcaa ctgataagta gcctcgtgac
    43921 tggtatctac agcaaccggc ttgtctaaag tatccttcat caaataggct tcctctaaaa
    43981 cagggttgat aatatcctgc caaaacacca ttgcccaatg ctctgggtgc ttcagtgtga
    44041 catacatcag aaaatcaggc tcatcagctg gcaccatagc aaccaccgaa taaatatagt
    44101 ttgtcaagcc accatctaaa taacctgtac cgtccttagt cgcaatctgc gcagtccctg
    44161 acttgacagc aactggtaat tgaccaacct taaccactgg acctgatgat ttcaaatgaa
    44221 gggttccaaa ttgtgggtca gtcccaacgt taatcatgta ttttcgtgtt tcactggcag
    44281 ccttttggga caccggcttt ccgacaatct ccttgtctga cacccggtaa gtatctgtat
    44341 ttgggtcata aatgcgacta acaaattgag gctctagcat cacaccgtca ttagagatgg
    44401 ctgtaaaggc tctaagcatt tgaatttgcg tcaccgaaat cccctgacca aaagcgctca
    44461 ttgcttgggt aacaatatta tcagaaggga aaatacctgg gtcttcattt tccaagccaa
    44521 agcgtgtccg gaatccaaaa cggaatttag ttaggtagtt catccatttg tcatttccca
    44581 ttttttgctc tagcttggtc atgccaacgt tacttgaaaa cgaaaagcct tgagcatagg
    44641 tcatgtactg ccctgtagaa atcccttcgt taatcgccca atcctgaatg gtagcatcag
    44701 caatggttaa gccattcgca ttgctaaagg tctcatcagg attaaagacc ttctcatcaa
    44761 tagcagctgc cagagtcata accttcatgg ttgagccggg ctcaaactgc ccctgatgga
    44821 gaatattttg ccagctatag cttttgctgt ttagcccctc caaggtgtct gcattatagg
    44881 ttggtctttg agtagtcgct aagatttcac cagtcttagc atttactaga gtagcactag
    44941 caagctctcc ttgcgccttc gactgaaaga cgtccatttg cgtttctaga aaggtttgaa
    45001 taggctctga cagggtggta taaacgtcct taccatcaac tggctttttc actgtctttc
    45061 ctgttccaag cagggtatta ccgtttctat ccttttgata agtgatgatt ccatcttccc
    45121 cagataagat gctatcaaag gccgcctcca tgcccatctt tccaactagg ctcttggtac
    45181 cgtcctcctt gttttcctca agtgaagcaa gaccaatcag ctctgaagca aaggtcccat
    45241 ttggatacat acggctagga cttgctgaaa atgcgatccc cttgatttta gctgcctcca
    45301 tagccttttg gatcgttgtc atcgtgctat aagaaatacc tgagccagac ggaccaaagg
    45361 aaacctgaaa aagacctttt tgcttaagct gcttaataac gtccttttcc tccataccca
    45421 gctgctcctt gaggatttga gcaaccttgt catactgaga cggttgaaca aaaagcttct
    45481 cgccagtcgc tgacacaaag gacttatcaa gaatggcata aatgctatag gtcgtcgagt
    45541 ccacagcgat agctgtgcca ttgcgatcat aaatcgtgcc tcgcttggcc tgaacagaaa
    45601 ccgtctcttg ataaaccttt ttggctccat ctgatagctt aacaccgaat ttctgatccg
    45661 tcccgataat gatcataaaa ttaatcataa agatgaagaa aataaagatg gttaagagca
    45721 tcatgttttg ccccaccctc aagcggttct gaacaggtgt ctttcgatca cgaaccacat
    45781 aatctaaaaa atatctttgc cattttgtca tagcttactc gaccttctta atgttatcat
    45841 ttcggttact aagccctgct ttgccagcaa tatcaacaat gcggtcacgt cgcgacagct
    45901 cattaacctc ttgcttggca ttgttaagct ctgtcctttt atctgagatc tgcctattga
    45961 gctgagtgat atgctgctgg agctgcaatt tacggctttg caggtaaata atgcttacag
    46021 ccatcgttac tgctgtcagg ataagcgtag cataaaaagc cttctcaacc ctcgagaaag
    46081 ttctaattct tttttgcaag gcttttgaaa ctgcctgagt tcttttttca ttaaccataa
    46141 tctatttccg aacttttctt gcgactcgta gcttggctga atgtgcccta ttgttagcca
    46201 ttagctcctt ttgacttggt aaaatcggct tacgcgaaac caattcaagc ttaggcttga
    46261 gctcatcagg tataaaggga agtccctttg gagcatcagc tgtgcttgct tctttaaaca
    46321 agtgctttgt cagacgatcc tccaaagaat gaaaggtaat cactgagata cggccatcaa
    46381 gggctagcag ctctatcgcc cgctggatag acgcatcagc agcaccaagc tcatcattga
    46441 cctcaatacg aatagcctga aagatttgct tggctgggtg tccttttttc ttgagctcct
    46501 tggctggctt agctgatttg atcaatgctg ccagctctgt ggtggtgctg attggcttaa
    46561 tggctctcgc ctgctcaatc ttacgagcaa tctgctttga gaacttatcc tcaccatatt
    46621 taaaaaagat ccgaactaag tcattgaaat cataggtatt gacaacctca taggctgtca
    46681 aagccgcctg gctatccatt cgcatgtcca agggagcgtc ctgcttgtaa gaaaagccac
    46741 gctctctctc atctaactgc ggactagaaa cccctaaatc atacaaaatc ccatcaatct
    46801 ctgtaacccc atgctccagc aagcgtgcct taaggtgtct aaaattgtcc ttaataaagg
    46861 tcacctgtcc cttgtcaata tagggcttga gctgctcctg cgcgtgatca atagcctttt
    46921 ggtcctgatc aaagcaatac aagtgcccct tatcaccaag cagagacagc aaataagctg
    46981 agtgcccaga gccaccaagg gtcgcatcta cataaatacc atctggctta atatccagca
    47041 tatcaacagc ttcatgaaga agtacagtta catgatgaaa ttcgtttgtc atagctctaa
    47101 ttgtaccata cttcaaaggg tttataaatc aaaaagtaag agaaaagggc tttcaaggcc
    47161 taagaaagtc cctctttatc ttactttttt tggcttagct atccttgaca tcaagatgac
    47221 taagagcttg ctgcacagcc tcatacagca gctcagccga ttcgagcacc tgcttggtct
    47281 cctttaacac ccgaaaatct gtcaccgaat tatctagcca aatatcaaag atcttatcct
    47341 gtcttgtatg agataagcta gaaggcaagc gcaactcact aaccttcagc tccttttgat
    47401 acctacagac cagatttctc acgtccccta ggctctcatt aatagcactg attttttgcc
    47461 tttttaccca gcttgttagt atcccattgt cgaacaaatc aaaaaatccc cacctcttaa
    47521 gctctttcaa tgcctcaatg acagactcaa gcttaaaagc taatgtcttt aggtctcgta
    47581 tggtttcttg cttctttaga tcccttgtca taagcctacc tccttagcag ctagctccga
    47641 atctggccat ttccattgat caggtattta ctgctggtca aggcctcaag tcccatcggg
    47701 ccacgagcat gcattttttg tgtggaaatg ccaatttctg ctcctagacc aaagacaaag
    47761 ccatctgtaa agcgtgtcga ggcattcaca taaacagctg ccgagtcaac cagatcctga
    47821 aaacgctctg cagcattgat attagctgtg atgatggctt ctgaatgatg actggtatac
    47881 tgattaatcc aagaaatagc ttcatcaaga gaggaaacca gatgaacaga catgatataa
    47941 tccaaaaatt cagccgcata atcttcctct gtggctaata cagccttgct aaacaaggct
    48001 tttgcctgct catctgctcg ccattccacc tgctgaacct tgctgatggc tgcttcaagc
    48061 atgggaataa aggtcgctcc taccttctca tgaataatca ggctttctgc agcattgcag
    48121 acgcttggtc tttgcgtctt agcattaatc acaaccttaa cagccatctc tagatcggct
    48181 gcttcatcaa cataaatgtg aacattgcca acccccgtct caatgactgg caccttagcc
    48241 ttttccttga ccgtttgaat taatctggca cccccacgag gaatcaagac atcaatataa
    48301 tccgttgcct gcatcaattc ctcagctaca gcatgagagg tatcctcaac cagcaaaaca
    48361 gcatctggcg taatagctga tgcctctaag gcatttctga taagcctgac caaggccata
    48421 ttagagtaga gagcatcttt gccacctcta agaataatgg cattattggt cttaaaggcc
    48481 aagctaaagg cgtcaacaga aacattaggg cggctttcaa aaatcatcgc aataacacct
    48541 aaaggcacac gcttttgggt tattttcagg ccgtccagat ttgtatagcc cttaatcact
    48601 tcgccaatgg gatcagccaa gtctgccacc tgtctgacgc cctgagccat cgcatggata
    48661 cgatctgctg tcaggcgtaa gcgatcgcac agaatctctg aaatcccatg ctcagccgcc
    48721 ttagccagat ccttggcatt ttctgtcaaa atcatatccg tctgggccac taattcctca
    48781 gccaaaaagg caagaaattg atttttatcc ttcgttgtca aggataccaa ggccctacta
    48841 gctgccttag ccctttgtcc tagctgttct attgtcatca cgcgtcacct ctttctatct
    48901 gtttaaacca agtgcctagc ttttctccct ccaagaccct taaaatgtct ctagggttgg
    48961 caccattcat caaaatcatt tgcccctgat gctcaaacat catctgggct gattggatct
    49021 tacttagcat accaccagtt ccaaatctgc tgcctgcacc gcctgctgag gctataatat
    49081 cctctgtaat ctctgtcaca tgactcctca agcgcgcgtc ctcatagatg gttggattct
    49141 tatcaaacaa accatcaatg tctgatagca taatcagcaa atcagccctt gtaatacgag
    49201 ctacgatagc tgataagcgg tcattgtctc caaattttgt tgaatgatcc atctcatcaa
    49261 cactaacagc atcattttcg ttgacaatgg ggacaatccc taaactaatc aggctttcaa
    49321 aggcattggt gacatttgcc agactttctg gaaaaacaac cacatcacgt gtcagcaaaa
    49381 tctgagacac tgtcgtctga tagtgggcaa aaatttgcga ataaaggctc atcatagcaa
    49441 cctgccccac acttgaaaca gcctgctgct tggcaagctg acttggtctt ttggccattt
    49501 tcaacaggtc aagcccaaag cccatggcgc cagaggaaac caaaataacc tcttttccct
    49561 tattcattaa gcttgaaatc acaaaggcta aatggtcgat cttttctaag ttaatcttcc
    49621 cattagcaag caccagcgag ctggttccaa ttttaattac aatacgcttt acatcttcaa
    49681 attgtcgttt catcatatta ggattatagc ataaaaaaca gcccagagga ctgttagatt
    49741 gaagccaaaa tcaatcagcc tatcagcttg ataaaaaaaa ggatcactgg ctacccattc
    49801 acctaagata taaaaatcca cctgatagcc actccaagca ggatttcctt tgtgacacca
    49861 cataccacgc tacgctttat cctattgtaa gtttaagtct gatcctcctg cattgtcctg
    49921 tcatttttaa tgaccatata ccaacactaa agctattgac aaaaacgcac aatacgataa
    49981 aatgaaagcg caaacagcta tatttactac ctaagggcca gaccttgctg taaagcgcaa
    50041 tacctgacag aaagaacacg tttcagaagt agcaagaaca agtcacaggc atactgtctg
    50101 gcacattggc gcaaaggcta ccagtgttca acaagactgg aacgcaaatc aataggctgg
    50161 aaatcaagta ggaaaaccgt atcatttaaa tttttggaat cccaagactc aattgttctc
    50221 aattagtttg ggggcttagg acgacagagc ctgtcagtca tctaaagcaa ttaattagtt
    50281 ataggaataa atcactatgg ttaaactatc aaaaagaagc aagatagcta tgtcattttt
    50341 aattgtcttt tgtggtatat ttttcgtcgc tcaaaaacga ttcggttcat cagaccaatc
    50401 atttaccgta aggccagacg cagatttcta tatagtcggt taccacaata ttgaaggtta
    50461 tcaattgaca aatgagcagc cgcaaaaaat ttctgacgct aagctcgaag tggtcaaagg
    50521 tcagatcaat caagtggtta aacgagcaga gctttcaaat cgttatctgg tcttttccga
    50581 ggaggggcca cctttggggg caataggaag acttatcgct cttgattttc aaaaaggcaa
    50641 cgtgacgtat cacccaacag ctgattatgc ctttacttcc tccggagtat caccagatta
    50701 ttatttcact tctacagcaa
//
LOCUS       DARYLD010000006        50228 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYLD010000006 DARYLD010000000
VERSION     DARYLD010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50228
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(438..797)
                     /gene="rplT"
                     /locus_tag="TU651_000295"
     CDS             complement(438..797)
                     /gene="rplT"
                     /locus_tag="TU651_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL0896332.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(858..1055)
                     /gene="rpmI"
                     /locus_tag="TU651_000296"
     CDS             complement(858..1055)
                     /gene="rpmI"
                     /locus_tag="TU651_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL0896333.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(1095..1625)
                     /gene="infC"
                     /locus_tag="TU651_000297"
     CDS             complement(1095..1625)
                     /gene="infC"
                     /locus_tag="TU651_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL0896334.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1640..1762)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1786..2466)
                     /locus_tag="TU651_000298"
     CDS             complement(1786..2466)
                     /locus_tag="TU651_000298"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL0896335.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2481..2978)
                     /locus_tag="TU651_000299"
     CDS             complement(2481..2978)
                     /locus_tag="TU651_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL0896336.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            3027..3224
                     /locus_tag="TU651_000300"
     CDS             3027..3224
                     /locus_tag="TU651_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL0896337.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3211..3699)
                     /locus_tag="TU651_000301"
     CDS             complement(3211..3699)
                     /locus_tag="TU651_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL0896338.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3744..4967)
                     /gene="pepT"
                     /locus_tag="TU651_000302"
     CDS             complement(3744..4967)
                     /gene="pepT"
                     /locus_tag="TU651_000302"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL0896339.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(5137..6156)
                     /gene="galE"
                     /locus_tag="TU651_000303"
     CDS             complement(5137..6156)
                     /gene="galE"
                     /locus_tag="TU651_000303"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0896340.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6224..8593)
                     /locus_tag="TU651_000304"
     CDS             complement(6224..8593)
                     /locus_tag="TU651_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0896341.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8673..9836)
                     /locus_tag="TU651_000305"
     CDS             complement(8673..9836)
                     /locus_tag="TU651_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0896342.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9850..11334)
                     /locus_tag="TU651_000306"
     CDS             complement(9850..11334)
                     /locus_tag="TU651_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL0896343.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11338..12579)
                     /locus_tag="TU651_000307"
     CDS             complement(11338..12579)
                     /locus_tag="TU651_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL0896344.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDEKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12563..12919)
                     /locus_tag="TU651_000308"
     CDS             complement(12563..12919)
                     /locus_tag="TU651_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL0896345.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12924..13613)
                     /locus_tag="TU651_000309"
     CDS             complement(12924..13613)
                     /locus_tag="TU651_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0896346.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13643..15388)
                     /locus_tag="TU651_000310"
     CDS             complement(13643..15388)
                     /locus_tag="TU651_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL0896347.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15385..16392)
                     /locus_tag="TU651_000311"
     CDS             complement(15385..16392)
                     /locus_tag="TU651_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0896348.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16413..17621)
                     /locus_tag="TU651_000312"
     CDS             complement(16413..17621)
                     /locus_tag="TU651_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896349.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17621..18424)
                     /locus_tag="TU651_000313"
     CDS             complement(17621..18424)
                     /locus_tag="TU651_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896350.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18424..19359)
                     /locus_tag="TU651_000314"
     CDS             complement(18424..19359)
                     /locus_tag="TU651_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0896351.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19349..20503)
                     /locus_tag="TU651_000315"
     CDS             complement(19349..20503)
                     /locus_tag="TU651_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL0896352.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20628..21476)
                     /gene="rfbD"
                     /locus_tag="TU651_000316"
     CDS             complement(20628..21476)
                     /gene="rfbD"
                     /locus_tag="TU651_000316"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL0896353.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21618..21956)
                     /locus_tag="TU651_000317"
     CDS             complement(21618..21956)
                     /locus_tag="TU651_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL0896354.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22254..23363)
                     /gene="rpoD"
                     /locus_tag="TU651_000318"
     CDS             complement(22254..23363)
                     /gene="rpoD"
                     /locus_tag="TU651_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL0896355.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23372..25186)
                     /gene="dnaG"
                     /locus_tag="TU651_000319"
     CDS             complement(23372..25186)
                     /gene="dnaG"
                     /locus_tag="TU651_000319"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0896356.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25433..25807
                     /gene="mscL"
                     /locus_tag="TU651_000320"
     CDS             25433..25807
                     /gene="mscL"
                     /locus_tag="TU651_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL0896357.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(26033..26209)
                     /locus_tag="TU651_000321"
     CDS             complement(26033..26209)
                     /locus_tag="TU651_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL0896358.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26364..27176)
                     /locus_tag="TU651_000322"
     CDS             complement(26364..27176)
                     /locus_tag="TU651_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0896359.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27244..28359)
                     /locus_tag="TU651_000323"
     CDS             complement(27244..28359)
                     /locus_tag="TU651_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL0896360.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28629..32270)
                     /gene="addA"
                     /locus_tag="TU651_000324"
     CDS             complement(28629..32270)
                     /gene="addA"
                     /locus_tag="TU651_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL0896361.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32260..35481)
                     /gene="rexB"
                     /locus_tag="TU651_000325"
     CDS             complement(32260..35481)
                     /gene="rexB"
                     /locus_tag="TU651_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL0896362.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35690..37090)
                     /locus_tag="TU651_000326"
     CDS             complement(35690..37090)
                     /locus_tag="TU651_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0896363.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37232..39373)
                     /locus_tag="TU651_000327"
     CDS             complement(37232..39373)
                     /locus_tag="TU651_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896364.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39380..40813)
                     /locus_tag="TU651_000328"
     CDS             complement(39380..40813)
                     /locus_tag="TU651_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL0896365.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40819..41496)
                     /locus_tag="TU651_000329"
     CDS             complement(40819..41496)
                     /locus_tag="TU651_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL0896366.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41510..42205)
                     /locus_tag="TU651_000330"
     CDS             complement(41510..42205)
                     /locus_tag="TU651_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL0896367.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42333..42968)
                     /locus_tag="TU651_000331"
     CDS             complement(42333..42968)
                     /locus_tag="TU651_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL0896368.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42958..43497)
                     /locus_tag="TU651_000332"
     CDS             complement(42958..43497)
                     /locus_tag="TU651_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL0896369.1"
                     /translation="MVKGVLRGDKLLEFEDIYLEYKDDVYRFVNKLCCYQNSLSDDIT
                     QETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMSMESLEIVDAKGHD
                     EPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAKDIGITVSSAKVLV
                     FRARKHIKRQLREEYGYEV"
     gene            complement(43786..47502)
                     /locus_tag="TU651_000333"
     CDS             complement(43786..47502)
                     /locus_tag="TU651_000333"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL0896370.1"
                     /translation="MMKRLGENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            47982..48527
                     /locus_tag="TU651_000334"
                     /pseudo
     CDS             47982..48527
                     /locus_tag="TU651_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            48608..49063
                     /locus_tag="TU651_000335"
     CDS             48608..49063
                     /locus_tag="TU651_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896371.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            49063..49350
                     /locus_tag="TU651_000336"
     CDS             49063..49350
                     /locus_tag="TU651_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896372.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            49343..49891
                     /locus_tag="TU651_000337"
     CDS             49343..49891
                     /locus_tag="TU651_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL0896373.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(50070..>50228)
                     /locus_tag="TU651_000338"
     CDS             complement(50070..>50228)
                     /locus_tag="TU651_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0896374.1"
                     /translation="EAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGVAV
                     VSRKRKKH"
BASE COUNT        14901 a        11495 c         9524 g        14308 t
ORIGIN      
        1 aagcatatca taacaataaa tcaccttatt gacacaaata gaaaggacac atttatactt
       61 atcattttca ttctattata ttaaaccata tcttgtgtta aaatacaatg aaattatgac
      121 attatggctc ctaaataagt tgttttgcat tttattattt tggtgatgga tttgattaaa
      181 actagaaatc atatatctcc ttatatgatc atcacttgat ggactgctca actgtctgat
      241 acaagattaa gccctttctt cttagttaac agctaccaaa gaaaggtaaa ttggctcctt
      301 tatactaaat tagagatagc taaaaacatc tcaaatactc ttgacaaaac gtcatgactg
      361 tcttatctag ctagattagc taacataagg cattaaaaat agacttagaa ggtttctaag
      421 tctacagtcg atctctatta tttgccaagc tttgccttag cagcatcagc aagggctgta
      481 aaagctgctg catcattcac cgctaaatca gcaagcattt tacggttaac ttcgatttca
      541 gcaagcttta ggccatgcat caattgtgaa tatgacaagc cattcatacg agcagctgca
      601 ttgatacgtg tgatccatag cttacggaag tcacgttttt tctgacgacg gtcacgataa
      661 gcatagtaat aagaattcat gacctgctct tttgcagtac ggaacaagat atgttttgct
      721 ccataataac ctttagctaa tttcaaaata cgtttacgac gtttgcgtga tacaacgcca
      781 cctttaacac gtgccattaa tattctcctt caaataactc ttataattct agtaaatacc
      841 tgttacaacc cttaatctta aaggccagta accattgctt taatacgctt gaaatctcct
      901 gcatgcacca tacctgcttt acgaagatga cggcgttgct ttttagtctt tccatggaaa
      961 cggtgtgatg taaaggcacg gaagcgtttc aaaccgcctg aacctgtacg tttaaaacgt
     1021 ttagctgatg cgcggtgtgt tttttgtttt ggcattttaa tattctcctc ttaacatata
     1081 gtgtaatatg acaattactt cttgtctgaa attggtgcaa gctgcataaa catttggcga
     1141 ccatccattt ttgctctttg ctcaataata gcaatatctt gagttgcctc agcaaaatca
     1201 gccagtacct tagcaccaat ctccttgtga gtaatcatac gtcctttaaa acggatagaa
     1261 accttaacct tatttccctt ttcaaggaac ttacgaccat tacgaagctt tgtttcaaag
     1321 tcacccttgt cgataactgg gctaagacgt acttccttta cagttacaac gctttgcttt
     1381 ttgcgttgct ccttttgctt tttttgatac tcaaatttga actttccata gtccataagc
     1441 ttggcaacag gaggaacagc ttgcggctgg attaaaacca aatctacatt tgcagcatca
     1501 gctaaagact gagcttcaga taatggttta atgcctaatt gttcaccttc aagaccaacg
     1561 agacgaactt cgcgaacacg aatctcatca ttaatgaata gatctttttt agctatgatc
     1621 ttcacctctt tattttttta gagaaaaacg aaagcggact taatgaacca agcccgcaca
     1681 cataatatcc cgtaggaatt tgacatgtag ggccagacaa cctaggtcgc aaggcgagaa
     1741 gctctcactt ctgcttttct cattattgac attctaacaa ataaatcatg ccatgtcaat
     1801 tattttttct gctttttcct gaataaattg gacaacagct gaaatcgtga taccggtagt
     1861 atcaaagata atcgcgtcat ctgccgcctt tagcggcgaa acttgacgat gactgtcctt
     1921 ataatcgcgt gccgcaatct cagcctttaa ggtgtcaaaa tcagctgcaa tccctttttc
     1981 aatattttcc tgataacgac gctgcgctct ttcttcaaca gaagcaatca aaaagatctt
     2041 caactcggca tcaggcagca caaccgttcc gatatcacga ccgtccatga taatagcacc
     2101 agtcctagca attcgtcgct gctgattcac cagctcctct ctaatctctg gcaaggcgga
     2161 cacccaagaa acattattgg tgacatcatt ttgcctgatc gccattgtca catcttggtc
     2221 tccaagaaaa accagttgtg agccatcagc tgctttttta aaagaaattg gacgctttgc
     2281 caattcttgc aggattagat tgacatcttc tttgtgataa ccatttttta atgcgatata
     2341 agtcgctgag cgatacatgg caccagtatc taaataggtg tagccaagat ttttggcaat
     2401 aatcttggct accgtacttt tcccacttga ggctggtcca tcaatcgcaa ttctaattgc
     2461 tttcatcttt tcctctttaa ttatttgata ttgacctcgt cacctggatt ggcataccag
     2521 tagccttggg tcatatgatc tgggtttagg gcctgtaatt gctcaacaga aattccagca
     2581 cgagctgcaa tagatgttgc tccttctcct gctaatactg taattgtctt tcctgctgcc
     2641 tctgtagaag gtgctgtttc agtcttagaa ggacttgttg tgtcactagc tgctgagcta
     2701 ttagagctcg cttttggctt tgtttttggt tttgagctga ccttctttgt tgtctttttc
     2761 tgagttgatg ccccgtaaaa tcctgttgtc tcattttgct tgttactacc gctgtttgac
     2821 gtatagaaga aaataaaaag tatggcaaca ataatgacaa agaaaacact taacaaggca
     2881 gtcaaccaag gtgtgctaat gagtgctcct cttgattttc ttgttcttgt cgccttattg
     2941 tcatcaacaa ttttttcttc ccatggttct ttagccatga ttcttccccc ttgttaattt
     3001 aacaaaatca tattagaata atacctatga aagtatctat ccttccagaa aaatgcattg
     3061 cctgtggtct ttgccagacc tactctgctc tttttgacta tcatgatgat ggtatcgtca
     3121 aattggctca gtctgatgag tcaagtcaac tcatagatcc taatgatcat gatgccatct
     3181 tagcagtaaa atcctgccct actaaagccc ttaccctcga gtaagaggct ttttttcgta
     3241 ttggtaggct tcaaaataat ccagtttaat gaagttatct agtaatataa cctctccctt
     3301 aaaataagga ttaatcgcta gatcatctaa aaaatatttt ttaggccatt ttctcatgta
     3361 aaaaaggtag ctcttatcac caacaaatag acaaaccgtt gatttagtaa cctcaatttt
     3421 ggtaattgag gcaatcatca gtctgtgcgg agcaaatagc tttaaagata cgatcttcaa
     3481 gacaccatta ttctcaatta caaaataacg atgcaggcca agtcccacta atatagcaaa
     3541 taaagcaaac aagacaaaaa cacgactcgg tatttctgtt ctttcataca ataaggacag
     3601 gccaataaaa ataggcgcaa cagcaattga ccaataaata atagaccaag acagctctgg
     3661 ctgccaatga taccttactt taccgaataa tttaatcatg cttttccatc acctccaatc
     3721 cgttctgagc attttgggtg atgttaagcc ttttggacaa tgccaagaat cacatcaact
     3781 gccttttcca tcgtttgcag actcacaaat tcaaacctgc catgcatatt ttcaccacct
     3841 gcaaaaatat ttggcgttgg aatccccata aaggaaatct ttgagccatc agtaccacca
     3901 cgaatcggct cgataactgg cttaatagct aggtcctcca taacagcctt agctagattc
     3961 acaggtgtca tgtccttttc aatcaccttt ttcatgttat agtactgatc cgtcactgtt
     4021 acaaatacac gctctgctcc aagctgacta ttcatctcct cagctagctg tgttacaaag
     4081 gcctttctag cttcaaagga gctatcctca aaatcacgaa taatataaga ggcctgtgct
     4141 tcttctacag taccagacat gctgtgtagg tggtaaaagc cttgatagcc gtccgttttt
     4201 tcaggacgat cgtcaactgg taattgacta tggaaatcca ttgctagctg cagggcatta
     4261 atcatctgat ttttagctgt accagggtga acattgcgac ctaacacctt gagctctagg
     4321 gctgctgcgc taaaggtttc atattgtagc tcgccaagcg gacctccatc aatagtatag
     4381 gcaaagtcaa catcaaaagc attaacatca aacttatctg caccaacacc aatttcttca
     4441 tcaggtccaa aggcaacctt aatgtcgcaa tgctcaatct gagggttggc aacaagaaac
     4501 tcaatagccg tcatgatttc tgcaattcca gatttatcgt cagctcctaa aagggttgtg
     4561 ccatcagttg taatcagggt ctgtcccaaa tattggttga gatttggaaa atcctctggg
     4621 cataaagaat agcctgactg accaagctta atctccccac cctggtagct ctcaataatc
     4681 tgaggggcta ctccttctgc attaaaatca gcagtatcca tatgcgcaat aaaaccaatt
     4741 ttccgagtca atttgctgct gttagctggt aagcttccaa tgaggtagcc attagctgga
     4801 ttgtaatgaa tgtcctgtag gccaatagct tccatctctg gctttagcac tgttagagca
     4861 aagtcagctt gactcttggt gcttggagtt gtagtgcttg ctggattgct ccttgtgttg
     4921 atttttacat agttcagaaa tcgttctaat aaagtttcgt atgtcataga tcacctcgat
     4981 aagttttcgt tactattata gcataaaagg acctaaaata cttgcctaag ctcagttttt
     5041 tacagtgctt tatctgttct gttacagttg cgttctcata aaaagacagc tgccaagaaa
     5101 gctcttgaca gccttgatta ttcatcagcc catgccttaa tcctcataac catttgggtg
     5161 cttgctttgc catctccaag tatctgtaca catcctttct aagccgtact ctgcagtcca
     5221 gttaagctct tttttagcct tgctagcatc agcatagcag gctgcgatgt ctccttgacg
     5281 ccttggtaat atcttgtaag gaatagacct gccaaccacc tgagaaaagg cttcgataat
     5341 atctagcaca gaatagcctg tacctgttcc taaattataa atagataggc ttggctcttc
     5401 agcaaacttt gcaagcgcag cgacgtgtcc tttagccaga tcaacaacat ggatataatc
     5461 tctaacgcca gtgccgtcct tggtctcata atcatcacca aaaacgccaa cacaatccag
     5521 cttaccaaca gctacctgag aaacataagg taataggttg ttaggtatgc ccttaggatc
     5581 ctctcctaaa tcaccagact catgagctcc gataggatta aaatacctta acaatacaat
     5641 atgccactca ttatctgatg catagaggtc cttgaaaatc tcctctagca tcagctttgt
     5701 cctaccgtaa ggattggtca ctgatagtgg aaaggtttct aaaataggaa cggtatgcgg
     5761 atctccataa accgttgctg aggagctaaa aatgatcttt ttacaattaa aggctgtcat
     5821 tacctttagt agggtcaatg tgccagagat attattgtcg tagtaatcaa gtggaatcct
     5881 gcttgactct ccaacagctt ttagccctgc aaagtgaatg acactcacaa taggatgctt
     5941 actgaaaata tctgttagca gctgttgatc gcgaatatct ccctgataaa aggtcacttc
     6001 tcttccagct atcgaggcaa cagcagctag gcttttagga tttgaattgc acaaattatc
     6061 aaccacaaca acgtcatagc cagcagctag cagttcaaca caggtgtgtg acccgatata
     6121 gcctgcacca ccagtaacta aaatacttcc taacattgat tatatacctg actttctaat
     6181 aattactaat attataactg attactccca aaaagtatat ctatcatttc attttaaaga
     6241 aatcaggata ggcattaatg tagcccttgc cttcaataag atcatattct aacagcttta
     6301 agtcagaggc cacctgcttt tgagcagcag ttagctggct gtcatcgcta tttctggtat
     6361 ccaagacatc tgtcaaaaga gcgtagtaag gagacacctt ggaatccgta tgctctagca
     6421 ataaagaggt aaaatcactg gaattaacac gaggtctagc caatttgttg gtctgatgat
     6481 tgctccagat gaaataatct gttaaatatt tgacctcctc atcattctta aagacctgat
     6541 ctggataaaa gccaggtaaa tgatcaccat aaaacacaac tgtaataggc ttgtcaacct
     6601 tttccagtgc tgataaaaag gcctttgttg acttgtcggt aatgcttaat aaattcacat
     6661 aactttgcag gctatccgtc tcagactggt ccagtcctgc taggctaaca tcaacatctc
     6721 ttagctctgt gtaccaaggg ccatgatttt gcatggtaat cactgaaaag aattgacttc
     6781 ttttggggtt aagctggtct aaaatattgt cataggttga ctcatcacta tagcttgagc
     6841 tcattcgtat caagtgcttt ggcttgtcag ctgaatcctc tgtggcaatg aaggtatcaa
     6901 atcccaattt gttgtaaacg atttttcgag agtaattgtt ggcgctcgca aggtgcaaaa
     6961 caatcctatc cttaggcgaa aaggcattac taatggcagg cgaaaacttc aacttaggaa
     7021 agacatcaga atacaaaatc gaaactgttg gattgaggtt atattttggt aggccaaata
     7081 ggctttgaaa ctccatatta gctgtaccgc cgccatagcc atcagaggtc attaggccac
     7141 tcgttgtggt ttccatgata tgatggatct ctgcaatagg atccttggcc aattgaaccc
     7201 cagaaatcct agctgggtca gcaaagctct cactcagtat ataaatcact gtttgatcag
     7261 aaatacgctg atgcctttgc ttattgatat cagcagctct agcttgatat ttctgataaa
     7321 tcttttgcat agcgctcttg ctatagcctg aaggctgatt aatggtgctg gtggtaacct
     7381 gcttgaacca aacaaagctc aaggattgaa accttgcatt ggttgtaaga ccataccagt
     7441 caatatcaaa gacattgtag actgatgaca gaactggaat accttttttg atttcaccat
     7501 ctttattttg gctaaataca aaaaggatag aggcaaatac caaaaggata gagcctattg
     7561 acatcagtct aagataaagc gctgatagga tcttttctct aaagtatctt ttatacaaaa
     7621 catagatcag cagacccgac aagactagta tcaaaataat actaatgatt tgagtcagac
     7681 taatgtaatt caagaaaaac ttaatctctt tgatccattt caaatctgaa aacaataaag
     7741 gctcacttcg ctgcttgtat ttttcaatat taacaatact gattaaagct ccgatcaccg
     7801 tattgacaaa taaagcaatg atatagttgt taatgagcaa aaacaccagc acaaaaaaga
     7861 gggtcaagac aagcacctga aacagggttg cacctggaat aatcactgcc ccatgaaaat
     7921 caccatatgc tgtgatccca gcctgaataa agtaattaaa gatgatccct aaaaataagc
     7981 tggtcactag agctaatcta agaccccatc gcttgctcaa aacctcgata aaggctgtga
     8041 cgatgaggta ataaaccaca aacgtcagca tataagagca aaagctatac ttaaagagat
     8101 tcaggctaac aaggtttgac tgactatcta aaggccaata atcattttgc ttaatcacag
     8161 tcttaaataa agagctgttc agcgttaaga ctgaaaaagc ctgactaagt aaaatgactt
     8221 ggattcctct gtttgattgg tagtccttct taaacaggta tttttttaag agaaccccta
     8281 aaataagcag gctgactaaa gctgccagac tgagtagcat ttcctgaatc gtacgattac
     8341 tgatggtaaa cctgctgttg tttttattga tggctaaggt gatatagcta ttagcaacag
     8401 catagtagct actgacagct acagaaacaa taagcagctt tgaggaagca tgcttgatca
     8461 gcaaacatgc cattccagct attaacacta agacaagcca cgaaccataa gctcccttat
     8521 ttaacgtgtt tttgcttacc gcaaaaatag ataaataaag agatgaaagg ctaaacaata
     8581 tcatatcaag catttctaga tcaactaact ggcgagcttt tgaaattatc ttcgttatta
     8641 taatggtcac accctttcct aactgctaaa agctagacat tactctctga ctcagaagcg
     8701 attacctctg ttactaattg acgaacagtg acctcccagg taaagcctga aagcacctgc
     8761 tgatgaatgg cttcttgcag gtcacaccgt ttttctttgt gctcaatcaa atgatccaac
     8821 tgccttttaa tatcagagac tgtatcatca atgatgattc cctgtgacgg gctcgttatc
     8881 acttccttga caccacctct atctgttgct aatacagcac atttcaacat acctgcctct
     8941 aatacagctg tcggaagccc ttcagcatag atggacggat taacaaaaat atcagattga
     9001 gacagcaaag acatggtctc agcaaaattc agcttgcctg taaagatgat ggactgatcc
     9061 tctttatagc tatctcttag tgaagcaagc aagggaccat ctccagcaac caccaagaca
     9121 gccctgtcct tatatgtcag ctgctcaaaa gcctccagca gcaaaagaat ccccttttcc
     9181 ttgatcactc gacctgcaaa ggtaataatg accttatcct gcaaagctgg taaataagcc
     9241 tttgacttaa agacctcata aagatcagaa tcaactgaat tgtagatgac gcctttggct
     9301 tttattccaa aggtcttgag ccatgccata ctgcgcttag acaccgcata aaagtcgggc
     9361 tgataggctt tgacaaaaaa ggtaattaca tgctcataga ctttagcaaa caagtctagt
     9421 agctggtgac ctttaacatt ttcgcccacc tgaacatagc caccaccatg ctcgatcaca
     9481 atactaggga tggcttttct tttggctagc ttcaagccca tgaggcttgt caaataaaat
     9541 cgtgtattgc agatcacaaa gtcaatacgt tcttccatca gctccgccag catgctatga
     9601 tacagatcat tcttatctaa aatcggatag cgctgcttaa atagctgctt tgaaggaaat
     9661 cggtaataag taatggcttg atctctttca atagggctca gctggtggct gttgctggtt
     9721 acaatgatga tacggtagcc taggctcact aattgttgcg ctattttttc tgtataccgc
     9781 tctactcctc ctagatgagg gcttgtaaag ccgctaaaaa tggctattgt tttcaaagct
     9841 tttcccttct tatgtataat attgcagcat tgttcgagta atcataccta ggatcaatag
     9901 caacgagcca ataagaacct gtttattact taataggcct tgggcctttt caaggtattt
     9961 gttattagag gccagcaaga ccaacactaa agggatcaca cccaaaaagt acctatcttg
    10021 aacccctagc acattaaggt ctccaactgg cgtaaaggtc aaataaaggc taaaggtaat
    10081 accgcctatt attcctaaag acatcaatcc cataccaaag cgagataagg tcggcagctg
    10141 aagcttgttg gcattagtga tgacaacagc aaaataataa accatactaa ttggcatgag
    10201 ctctaccata ccgtatgata aagggccaaa catgtaaatc cctgaaggat taaggatatg
    10261 agccaacgtg tgtcttagca gcataaagcc atatactata gggttcctta acacagtcag
    10321 tagctgctct ttagcattga ccttctggag aaagtcagcc atatccacct gaggtgactt
    10381 gatttgacca tataccttta accaaaaaac agtcacaacc agcaccgtca gaattgacaa
    10441 cagctttagc agaaacgtgc gagaggcttt tgctccaaat tgacgtgaag ggataaaaag
    10501 cagcaacaaa atcaataaaa tataaggcag cttagtaaag gtaatgattg agcacagcag
    10561 ggtataccaa aagagcttgg ataagggaat cttttcagtt gtagccatct gaacaaataa
    10621 agaaatcgtc agaataatca atccaataga gacacaatcc tgattataag aaccagcaag
    10681 atagatattc atcggaagga gacttcctac agcaagcagc tgcttgcctg ctgtcagcaa
    10741 tcgtaaggca acaaaaacca agatggcata ggcaagaaca ttacaaagcc tacctaaaag
    10801 gtaagataag cccatggtca agcctaagct ccttccaata aataagccta ttacctgtgg
    10861 tatgtaggca aagttataat agccatttgt tgagcgaatt tccttaaatg aaatagcctc
    10921 atctgtatgg tctctgctcc acagctgaaa gcgtaagggc ttgccattgt tgtggtccat
    10981 aagattaatg tcatcagtca ccagcagctt tgagtcatca ttggttaaat taagatttcc
    11041 ctcagataag tataaggctc ttgcaaagtg aaccctctca tcaggaatat cattgatcgg
    11101 tgagatgaag gcagagacag aacccataac cacaataata agcactgtcg catattccat
    11161 atttgaaggt aaaaagataa tcaaaagcgc agcaattgca actaatattg ctaaaaattt
    11221 aatgggtaaa tccgttgatt gcgtatataa aagcagcaac acaagaaagg caccaagtaa
    11281 aacaagcaaa gccttactcg ccttttgcaa tttgtcaaat aaggtatcta acatatccta
    11341 tttccttttt tccataatgt acaagccata tgacaatagc agccaaatca tcattgaaat
    11401 tataaaacca taggtaactc caatcacccc aaagcttcta gccaaagaac cagtgatggc
    11461 tagtgaggag ataaaggata caacataagg tatcacaagc aagtgctgct ttctgataat
    11521 ggtaatcaaa ttatcaatat aagtggcaaa ggtgctgata atccctccaa aaataagaag
    11581 cataaaatca agctggtaat gccttaaatc aataccataa acaagcgata gcaccggcag
    11641 ccccacaaaa tagctagcaa gcaagatagc taggcttgct aatagcagca ctagactgag
    11701 acgacgctct aattgtgcaa agctcttctc gtcctctttt gaatggtaaa tggccagctg
    11761 agtgatcata ggccttaaaa acaagaaaat caggttaatc ataaaaatag gcataaacaa
    11821 aatattaaat tctgtttgaa caccggctgg gatcagctgc tttgagtaaa gctgctccaa
    11881 aacaaacttg ggctggttgt agatataaat gagtaaaaaa ccatttaaaa agaggggaaa
    11941 gctctccttc aatagcccta agatgctttg agcatcaata cgacgctcaa ggctcgtaaa
    12001 ggaaactgaa ggggttatgt caaatagcac aatacaagcc actgaaataa gacatatcac
    12061 gatcaaagac aggactagct gcttggtcag aaccagacag agcgtaaagc caagaatcac
    12121 cagcatattt cgataaaaca aggatttgcc ggcaatatct aagcgctctc tttgttgaaa
    12181 cattccttga aacacatcag aaatggcatc tgtgcaacga tacaagcaaa tcaaccaaat
    12241 cactagcccc ttaaacccac tatagctccc caaataaata tagagcactg aaatggctat
    12301 catcaagaaa caggtgacta gtcttgtata aaaatagtct ttgaagcggt acttgtgtaa
    12361 tatatccgtt gattggaaat ttctaatctg aaataagcca atagtaatca gctgatttcc
    12421 aatagcatag gcaaagctaa aggtatctga agctgattta gataagaccc gagacacaat
    12481 catcagtaaa atcactgata ttagtgctgt cgagctggtt cccaacacat tccaaataaa
    12541 aatcgactga tccgattgaa tcctactgct ggttttcatc ttcttcctgc ttttccttct
    12601 cattaagggc taaatactga atcatttttt taagcttaat ctctgtccga gacaattttt
    12661 gagtgataaa aaattggttg atgatgagta aaaaaatgat tgatagaaaa acaaaatttg
    12721 ccggcgattc aaagcctagc agccttgaaa aataaaccgc agcatttgga aacagtgaca
    12781 gcaaaagcac tattaaagag aaaaagagcc aaaaaaagct atcttcaatt aaaattttgg
    12841 atctgcgaat gctatctagt ataaacatgg ctgtcaataa tgcaacaatg atcaaaatca
    12901 gctgtaaccc aataaacatc ctcttacctc tttctaaagt tttgaattaa aataatcgaa
    12961 ataaacatgt gaaccatgta tttaatagat ctagaaagag tgaggtagct ttgaccagcc
    13021 agcctatcat tcatttgcac ctgaacctca ctcaccctat agccttgtcg aataagataa
    13081 gagatcgtat caggctctgg agtatagtta atattagttg caaaaatcct gatcagctcc
    13141 tgattaaaca ttctcatacc agaggtcgga tcggtaatac gctttcctgt ggttagcttg
    13201 ataaaaaagc taataaggct attgcctatc attctcaagg atctattctt ttcagcactg
    13261 acaaaccttg atccaatgac acaatcagca ccagcattaa ttgaatcgct caaagcctca
    13321 atatactctg gcaagtgttg accatctgca tcgaactgga gtgctttagc atatcccttt
    13381 ttaaaggcat atttaaagcc cgtctgaata gcaccagata agccaagatt ttccggcaaa
    13441 tcaatgatat tgtaatggtt atgatgacag atctctgatg tccgatccga agagccatca
    13501 ttgataatca cataatcata ttgaggaaaa tgtcttttga tattttccac tactttttca
    13561 atcgactcct cttcgttata tgctggaatc attaccaata agtctttttt catatcgtca
    13621 aatattctct ctattcattc gtctaaacgc gtctttttag caatcgcttt atgatataac
    13681 ggatagcctt agctggccca atcacaatat attttaaggc tccttttata cctcccatat
    13741 agtcaaaatc gacataggta tgtggcacac tgccttcacg caggtttaag agcttattat
    13801 caataaatgg tgtcaatagc ttttcatttc ttgaaattct aaaatcatag tgtctgtccc
    13861 aagcaatata aattaagaga cgttcaatgg catgcaggat cgaattttga gacagaggct
    13921 ctgctggaat atcagcctca cttaggtcta agtcaaacaa gggctttaag gcatcgtatt
    13981 taaaccaaac aaaggtgcca tagctcatga caaaggtatc catcgtctga aaatcaatgc
    14041 gttttgtaag ccccattgcc tgccaaagct gattcatttc aggggcaata aggtgctcat
    14101 tccaagcgtc aacaatttta ttaaaacgga aaaaacttgg aatatctgct atcacaatac
    14161 cgatagcatc agcagccagt gctgttagga tttgatccgc cggcttcacc atcatatcaa
    14221 tcaattcagt gcgccaggat tggcccgccc aaaaatctgc ttcctttgat tttttggtat
    14281 gaaaatgccc aatataatca tattgagaca atcgttcctt taaggtcagc attggcaaga
    14341 catctcgacc gatatttcct gtcaccaata tgtcagcact tgccccgctt tctcgtagaa
    14401 tttctttaat ctcagccttt ttagccttgc tatcggtcgt tatgagcaag tcataatcaa
    14461 aatgaaaatg actaaatgct tctaaaaact ctgacaataa atcaacataa aaaacatgaa
    14521 gatgaacagc aattttcttg ctttgatcaa tgcttatcgg ctgctctggc aggtatttat
    14581 gtgccagaag atacttagca tctggtggat ggacctgcga catatgatcc acaatcaagc
    14641 tggcagggta tgtcgttttt tggtcaataa aatccaaaag gtaaggagca atgtgctggt
    14701 tagcgtcaat agccttaacc ttgataaagg gcacatggtg ctttaagatg gctgtcggat
    14761 tgtaataaga gaaatccgca tgcagcatag aggacgagtc ctccttggtc gtatcaaata
    14821 ccgtcttgta tcgaaagcca gcctccacaa agacagtggt tattctggtt tcataattgt
    14881 ggatcacatc ttgaacgtct gttagctcaa cgatattttc ccaaaactgc ctaaattcct
    14941 tactatgaac gagggatttt ttgaagctga taaaatagct ctgaatatgc tctttaaagg
    15001 ccttggtcgc tcgattgttg gtcatgcccc agaaatcaac tgcttcatct gcttcatatt
    15061 tgagataata aggcttcata tcccaaagcg gaccaaagca ggtatcgttc ataatcgtga
    15121 ttgagtcaaa gtcaacaagg tgctcacagc ctaaggcctt cataccatca tgccaagctg
    15181 caaaatcata gcctttattg tgtcgttgaa taaactgatc catcaaatgc cgctgttcaa
    15241 gctgctcaag gtcctcttga tggatatcac tatttgaaat aaagacaatc tttgaaaaca
    15301 aggctctcat ctgttcgagc tggtaataaa catgatcgct taccttatga tatttattga
    15361 aatgcacata caataataga cgcttcattt tttcctccta aaaagctcaa gcagctttga
    15421 taggtacctc caacgacgtg aggtaaccac acaattgtat tgatgggtta gcgcttcaac
    15481 ctcttgcctt tgatgatcaa gctgctgctg tagctgatct atcttctctg cctgtagagc
    15541 ctcctgatct gcaagcgtct gtcgtaattg atgaatggta tgacttaatt gatgaatccg
    15601 aatttcattt ttagcgtcct gctttagtaa tgcttttgca atagcttcca tattggctgt
    15661 agggtattta gacaaatagg acagctgggt ctccaacaag ccttgaatac ggcccagcat
    15721 tttttcctct gctgccggcc ttgaatctga attatccgtc attcgataaa cagtggtcga
    15781 atccttcaaa taggctagag aggttgactg aaacagctct aattgtatgt caaaagtgtc
    15841 gtctgacgtc tccaaatcaa tgcgttgatt aactgccctc atcagatcag cctccaccag
    15901 ccaggttgat gacatggtca ttccttttaa agcaagcatt ttctcgtagg tgtctgttaa
    15961 gggagtaaag ccactttcaa aggcattgct ctgaataagc ttgccgtcag tatctacaaa
    16021 atcaaagtca gtattagacc attttgaatc tggtgagcta tccagcaaat caacctgctt
    16081 ttgtagcttg agagtatcag tccaatagtc atcaccatca catctggcaa tatactgtcc
    16141 ctttgcctcc aaacaagcct tgacccaggt tcttgcaatc ccaagattta cctcattaac
    16201 gatgagtcgt atacgatctg gaaagctggc ttgatagtcc atgaggatct gtctggaata
    16261 gtctgttgaa gcgtcgtcaa tgacaataat ttcaacatca aagctggtct gttgggctaa
    16321 aaagctgtct aaggcctctg aaatccaagg ccccttatta taattggtgc aaataataga
    16381 aacttttttc ataggatgct ttctaatgac aattattgat taatgagcca gctaccattt
    16441 ctttgatata agccactggc agagtccaaa gcagacaggt catctggagc aatatcgttt
    16501 cgttgaagca cgactaatgg ggaatgatta gctgttaaaa agagcagcat ttgcccgttt
    16561 tgatcgcgaa cagtcacctc aagctttaat ttgatatcat ttaggtgtga gagctgacac
    16621 tggtaggata tgttcttatg accaggacca cttgtcggtt gatcctgtga attgtcatta
    16681 tatacccaaa tattgcggtc aatatcagtc aacgaaaagg caacataggt aggctcgtcc
    16741 tttaagacat gataggaaat ctcaaaggaa atgggctcat ctggactaag gcttggctta
    16801 gaggtcaacc tcacctctaa ctggcttgcc aaatcagaca caggctcagc agcagctcct
    16861 tgctcagcat ttttcaattc agtattatca acactgtatt ggttagcgac atcaaagggt
    16921 tcgccgtaag ccttgacaag gccattttcg atgaggactg cgcgattgca gtattttttg
    16981 acagccccca tatcatgggt cactagtata gtagtcttgc cgctctcctt gcgctccatg
    17041 aagtagtcat tgcattttcg ttgaaaggcc tcatcaccaa cagctaacac ctcatcaaga
    17101 atcagcacat ctccctgtgc cttgatagcg acagaaaaag caagacgaac ctgcatgcct
    17161 gaggaataat tttttaattt ttgattcatg aaatcatgca gctcagcaaa gtcaacgata
    17221 tcatcataca tatcatcaac ctcttctgtg gtaaagccca gcattgcgcc attcatgtag
    17281 acattttcac gcccagtcaa ctcaggatta aagccaacac caagctcgat gaaggacacc
    17341 attttcccct caactgtgac ctgtcctttt tctggaacat aaatttgaga aataattttt
    17401 aataaggttg attttccaga gccatttcgt ccaacgatgc caaaaaaatc ccccttatac
    17461 acgtcaaagc taatatccct tagcacatgc tgctcggtat agcccttaat gcctttaaaa
    17521 cggttaacaa gagcagtacg aaagctcttg gttgcctctg ttggcagctt aaaggactta
    17581 ctgacatgat caactgttac tgcaatttct ttattagcca ttagataatc tccgcaaact
    17641 tcttagcatt tttattaaac actgctaccc caagtgctaa taggacaaat ggaatgaggt
    17701 aaggaatgat gatatagcac caatttgtcg acatttgcca aatggtcaca ttagctctgt
    17761 caatcagcag ataccgcaaa tcttgaataa tctgtgctaa aggattaagc atcaaaatct
    17821 tggcagcaag agggtgtcgg tcaaacacaa aggtaatcgg gtagatgatg ggagtcacat
    17881 acatacctgc ctgcaataga acctcccaaa cctgagccaa atcacgataa taaacaaaga
    17941 cggtagaaag catcaaggcc acaccaactg taagaacagc cagctcaaca aagagtggta
    18001 aggccagata agcgtgagga gataaagtaa ctccattgat agctgcaaaa accaaaacca
    18061 ctaataggtt gattgaaaag ttaatcaatg ctcctaaaac tgctgaaaaa acgatagtat
    18121 gctttgaaaa attcaatttt ctaagcaggt ctcctcgcga tacaatagag accattccca
    18181 tactggttgc ttctgagaaa aaggaccaaa tcacattggc aagtaaaaga gcaactggaa
    18241 aatgaggaac gtcaccacca gttcgcaaaa acctgataaa caccaaatac atgatggtaa
    18301 acatcatcaa aggctttaag atagaccaca aataaccaat agcactgccc tgatacctta
    18361 gtttaaagtc tgttttaaca agctctttca aaagaatacg attcttttta ctcaataatt
    18421 ccattattct tttctcctat agccaaattt ggtcatgatc aatgccataa aaacaagggt
    18481 atgaaaggca cgatttttcc gaaagccata cgctttgaaa tcagacagac gctgatagaa
    18541 aggcctatcc aaaagcccta cgtaagcctc aatcaatctt ctgtcagccg gatttagctg
    18601 caagtctagc aattgccttg cttgatgttg actagaaaca ataagccacc aatacttctc
    18661 tatgagctta tggggcttac gccactgctt cagtcgctta gaccaggttc ttgcccctaa
    18721 aacattagca tcatgctgac gatagagctc tgttgccaca tctagataca caagctctcc
    18781 ctgcgctgct gcaatcaagg ctaaatacca atcatgcatc accacatgct cacagctcac
    18841 ccactgctct gccagcgcgt gattaatcat catagtgccg cctgtgactg tgttttcagt
    18901 caactcctgg actagctgag tattagcatg atgtgattgt gtttggatca tactctcatg
    18961 acgtacttct aagtcttgat tgaccacctt taggtctgtg tagactagta agggctcgct
    19021 tatcttgtgc ttttgcgctt ctgccagagt aagctctaat ttattgtcta accacacatc
    19081 gtcttggtca ctgaaaaaat aaatatctgc cttttcatat gttaaaaggg tgtgaaagct
    19141 tcgaatcaca ccgaggtttt cctgcacatc agcattaatc aagcaaattc tcggatcctt
    19201 tttagcaaaa gcctgaatga tggcaagcgt tttatcagta gagccatcat ctctgactaa
    19261 taaggtccaa tcctgcaccg tctgcctttg aatgctttgt atttgctctg ctaaaaaccg
    19321 cgccccgttg taggtagaca ttaaaatatt aatcttcatc taaaaataag gcctcatact
    19381 ctcctacaat tttctcccag gtatattctt tggcaatgat ttgcttagct ctttctccca
    19441 aatcagcaaa cgattccttt tgatcaaccc tgttaatcag tccagtaagg ctgccctttt
    19501 cttttgtcca ataaagggct gctgttttag caactgattg attaaaggtc actcccaaaa
    19561 ccaaattaag ctgggtatgg gctagggcct ccaaaagacc tggattggta cctccaacct
    19621 catgcccatg aatataagca aaagcatgct cacgaatata agctaaaagc tgcttatcat
    19681 actgtgttcc aacaaatttt acacgcgcgt ccttatcaca gccagttgca ctaaccagcc
    19741 gctcaaaata aggatttttg tcatggttgc aaataataac caaatcccgc tgagtagatg
    19801 atgccataaa ctctctaatg gctgtttcat agttgttttc aggaacaaag cgccccaaaa
    19861 tcaaatagta ttggttttct gttatctcaa atgtttgaaa gtaagttctg actttttcat
    19921 ctgatgtaga caaacaagac cgccctattt ctgtcccata ggcaataaaa gtcgtttttg
    19981 cccaaggata agactttttg atgtaggctt caatgccaat attatctgag atgaccaaat
    20041 cagcatgctt tgtcatttgc ttttcggcgt atttcaggta ttgctgaaca ggcttagacc
    20101 attttgaacg cttccattcc agcccatcag gattaatcaa caaacgccca ccacgctggt
    20161 gaatctgctt tgcaaagggg gcaataaagc ctccaatggt attgcctaga acataaaaaa
    20221 taggcttttg aatatgatac ctatcaatat aagctaaagc gtgactaata gccatcatat
    20281 cataagcaat cactctagct ggaccgagct taggaggatt gatataaaaa caatctgctc
    20341 ccttgtacac aaaatgctcc ttgtgcttgc tatcgctcaa gcaggcaata tgataggtaa
    20401 tgcttttgtt ggtctgatta gtgactaatt cttcaacaaa ggtctcaaaa ccaccatact
    20461 ttgctggtaa accgcgactt ccgatgatga aaacatcctg catagcacac tgccccattc
    20521 taaaatataa ttagtagtat tataccatat aaacaggtct tatgcgacat aaaatccatg
    20581 aaaagagagc caatctccta gatcagctct ttagtgctat cgcttattca ttgctgttgc
    20641 ttgtaaaaag cctccagggc ttcttgccag gtaggaatca caaaaccagt tgccttagcc
    20701 ttatcaagat tcatggttga gttaaagggt cttttggctt tagcaggaaa agccgatgaa
    20761 tccacaggca caacctcgac agctgtctct tttaagattt ctctagcaaa atcataccaa
    20821 gtggtgtctt ctttagcatc atttgacaaa tgataatagc cataaggctt gcgattgtct
    20881 gctagatgac acataaactc agccaaggtc ctcgtccagg ttggacgccc atgctgatca
    20941 ttgacgactg tcaagcgaga gtgggtctta gcaaggtttt gcatggtaaa cacaaaattc
    21001 ttgccataat gaccaaacac ccatgcggta cgaataatgt aaaattgctt ggtatatcgc
    21061 tcaacagcca gctcacctaa gcgcttagca cgaccgtatg ctgtttgagg atcaggagta
    21121 tctgtttcta gccattcctg accagctggc ttttgaccat caaaaacgta atccgttgaa
    21181 atataaacca aggtcgcccc gtagcgctca caagccttgg caatatgctc agtaccagct
    21241 acattgatag cttcattcag tgcttttcct tcttcttcag cagcatcaac tgctgtgtag
    21301 gctgcacagt gatacactaa gctaggcttg acctgagcaa aaacctcctc tactttagtc
    21361 gcgttggtaa tatccatttc agcaacatca acagcaacat aatcgacgct tcgttcgtct
    21421 aaaagataac gaagctctgt tcctaattga ccattacttc ctgtaattaa aatcatcttt
    21481 tctcctttgt aaaggtctta tttctttgag ctaatcacgc agctcactcc catctaatcc
    21541 taagagaggc ttttttgatc agctgaccct agcaagacct ttgttgtggt atcgtatcag
    21601 ccttgctttt tatctagcta ccgaatacct agggcaattc tcgcatagcg gctcatcttt
    21661 tcaacgctcc aaacagggta ccagaccaac tttacctcaa ccttggtcac ctctggaaca
    21721 tctctcatcg catcatgaat atgatcagtc aacaaatccg ccaaaggaca gcccattgtg
    21781 gtcaaggtca tgtcaatctc ggtatgacca ttgtcatcaa aacgaatctc atagaccaag
    21841 cctagattca caatatcaat acctagctcc ggatcaataa ccgttcccaa agcttcaaga
    21901 atccgatcct tgatagctgc aacctgctct tctgtgtatt ttaatgtttc agtcatagct
    21961 attcctttca cttttttcga agacctgata tgatgccaag tcaaaaacca gcccaaagac
    22021 cagcgcattc agcataccta tgatgcccta agctgactaa cattgatagc ctctttttag
    22081 tcacccttac attaacacta gtctttagct actggctagc aaaggtaatc tcataaacca
    22141 gtaactaggc ttggagtcgt tgaccatagg ccactcaccg tcaaggagag ataacgcatt
    22201 tcgggctcgt ctcctatttt tagctcgccg ttaaaaaggt ccaccggacc tttttaatcc
    22261 tcaatgaagt ctctgagctg cttgctgcgg cttgggtggc ggagcttacg caaagcctta
    22321 gcctcaattt gacgaatccg ttcacgagtg acattgaaga ccttcccaac gtcctctaat
    22381 gtacgcattt tcccatcatc aagcccaaag cgcaggcgaa gaacattttc ctcacgatct
    22441 gtcagcgtat caagcacttc gtctaattgc tcacgaagaa ccacacgagt tgtgtaatca
    22501 acaggatttt caatcacttc atcttcaata aaatcaccta aatgactgtc atcctcttca
    22561 ccgattggtg tttcaagaga cactggctcc tgagcgattt tcagaatttc acgcacctta
    22621 tcaggggtca tctccatacg ctctgcgatc tgctctggag taggatcctg ccccaattct
    22681 tgaaggaggt tgcgctgctc acgcactagt ttattaatgg tttccaccat atgcacagga
    22741 atccgaatgg tacgtgcctg atctgcaata gcacgagtaa tggcctgacg aatccaccag
    22801 gtcgcatagg tcgaaaactt gaagccctta gaataatcaa acttgtcaac agccttcatt
    22861 aagcccatgt taccttcttg aatcaaatca agaaattgca tgccacgccc tacataacgc
    22921 tttgcaatcg acaccaccaa acgcagattg gcctcagcaa gacgctgctt agcctccata
    22981 tcaccagcgg ctactgcaac cgctaaaacc ttttcctcat cacttgtcag cagcggcacc
    23041 acaccgatct ccttgagata catgcgcaca ggatcgttga ccttggctga attacttccg
    23101 ataagctcct cgtctgtcag ctcctctggc ttaggctctt caacgacgta tttagatgag
    23161 ggatttcctt ccttatctgt aatggaaatg ccaccatctg tcaaacgctc aagcaaatca
    23221 tcaatttggt cagcatctaa ggtaaatgga atcacgagtt tttctgtgac ctcatcatca
    23281 gtagctgttc cttccttttt atgatgacga ataaactccg caatttgaac gttaaaggtt
    23341 gtaatttctt tttcttttgc catattttcc tctattccat ttttcttttt tcagcaatga
    23401 aacgctctaa agcctctaga gccatctggt ggtcaccctt actgctagat tccctaatct
    23461 gctttccttg cctatgcagc tctctttgct ttagcaatgt catttgcctt gataaaatat
    23521 cctcaatctc accgctagct atctcatcag gaagattttc ctctaaaacc cggtaatagg
    23581 cttggttaac ctcttcagac agttgcgata ggtcatagga ggtaatctgc cctgtggcct
    23641 ttagctgctc atacagcgtc tgaagggctg gtgtatcaaa ataaaaatcc ggccgatgac
    23701 gaaattcatt gagcaaatag tcgtgatgaa gcaggcgatg caggaggtga ctttctgttt
    23761 tagccaaggc tgtcatgctt ttgttaatcg gtaaggtcac cagagatgcc tttggttgac
    23821 tagcctgtcc ttgttgtaag ctttgcctat cttgtagcct taaagcattt accgattgct
    23881 ccacctgaaa ataatcaaaa tccggcagca aatcagccac cttattaata tacgaatttt
    23941 gtgcggtgat tgagggtgct tgagcaataa tctgtgatat atgctccaca taagcaatct
    24001 gcgattgcag gttatccata ttttcaggct tcaggtgatc aatcaaaaac tcaacactgc
    24061 taatgcgcga gtgctggagc aattctgcta gagcctctgg tgaatgctgc tgaacaaatt
    24121 catcgggatc cattctattt ggtattttca cgatctccac ttgaaaatct gccagcagct
    24181 caagagactt ggcaatagca ttttgcccgg cgtcgtcacc atcataagtc aatacaacct
    24241 tttgtgtcag ctgcttgagg tgcctaacat gctctggcgt caaggctgtc cccatagagg
    24301 caacagtatt accatagcct gcccggtagg ctgcaataac gtccataaag ccttccatca
    24361 aaaagacctc atgagtctta gcgattatcg gcttggcctt atcaaggtgg taaagctcat
    24421 aggacttgtt aaataggacc gtagcccttg aatttttata cttggcctgc tgcttttcta
    24481 tatcctctct tgcccagata cgtcctgaaa aagcaatcat attgccctta tcatcacata
    24541 agggaaacat gattcgatga cgaaaggcat cataaatagc atttgattgt tcagaaacat
    24601 gaaacaagcc tgaggctgtt aattgcgcct cagtatactt ttttgacaag gcttgataaa
    24661 ggtagtccat ctcgttaggc gccaagccaa tccgaaaata ctctattagc tgatcatcaa
    24721 gccctctttg ataaagatac tccttggctc tttggccaat ctttgtcgtc atcaaaaccg
    24781 catggtaaaa cttagcagca tcttcatgaa gatcaattaa agcctgatga gggtgctgct
    24841 tttgactcaa actagtctga cttggagcaa cagtaactgc cataccagcc ttatcagcca
    24901 caatctgaac actttctaaa aaaggaacct gccgatattc ctcaataaac ttaaaaacat
    24961 cccccgactt accgcagcca aagcagtgaa agaactgtct atcttcgatg acattaaaag
    25021 agggtgtttt ttctttatga aagggacaca atccaaggta gtgccgacca gcccgcgata
    25081 gatggacaac ttctccaata acatcaacaa tattgacatt atgcttgatc tgagaaatca
    25141 tctctttgtc aatagccaaa ccgtcacctc cccacaaaaa gcccattgta aatttacatt
    25201 tcattatacc attgaaaatg agctttgtaa attgtaaaag cacaatcctt catcatctaa
    25261 agcccgctac atcaagcaat aagctatgct aaagtattga cgtctcttat gatcactagc
    25321 ttgactagca gtacagcatt aagtagctca tcagtccttg ataagctctt ctattagcct
    25381 ttttgaccta tttgtgctat gataagatta tctgaaaaaa ggggagtcaa tcatgctcaa
    25441 agaattaaaa gcatttttat ttagagggaa tattatcgac ctagcagttg cggtgattgt
    25501 tgggagcgcc tttagcgcta ttgtcacatc atttgtcaac gacattatca caccgctgat
    25561 cctaaaccca gccttgaaag ctgcaaatgt ggaaaacatt gctcagctcg cctggaatgg
    25621 catcaaatat ggcagctttc tcagtgctat tatcaacttt ttaattgttg gtaccagcct
    25681 tttctttgtg gttaaggtcg ctcaaaaagc aatgcctaaa aagggagagg aagagcccgc
    25741 taagcccaaa acaccaactc aggaagaatt attacttgac atacgtgatt tgttagccaa
    25801 aaaataactc aaagctctta cagcagctgg acctgtccgg ctgctttttg atatacaagc
    25861 acagagcact tagcgatcaa aagataatag aaccggctct atttgctgtt ttagcatatc
    25921 attgctattt ttatcagcag caagctaagg taaaaaaaga caaactagta tcctcatact
    25981 ggtttgcctt caaactaagg cagcctacaa agggccgcct tttttatgat gattagaatt
    26041 ttttacgttt gcgagctgct tctgatttgc gtttacgctt tacagaaggt ttttcgtaga
    26101 attcacgctt gcgtgattct tgaagagtac cagctttagt aacagaacgt ttgaaacgac
    26161 gaagagcatc atcaagcgat tcattcttac gtactactgt ttttgacata tgtttcacct
    26221 cctcaagata ttgtaacatt ttcacgttct agcttatctt acatgatttt tcggaaaaag
    26281 tcaatgatct tttcttgatt ttgaggtcat tcttaaaaaa ataccttaaa atttgctgct
    26341 gcattaggca tcacttggca aggctattct actgcatttc ctgttaataa tgctgcttct
    26401 tgaataaagg ccttgtattt gccatccttg tttaattgct tgatcacctt attaatggtt
    26461 tgccttaggt catcactccc ctttggcata gctacagcct tagcatctcc atcacttgcc
    26521 tgcaatttaa atggtgctaa agccaggtct ttatgttgag ctaaaaagcc tgcagctact
    26581 ggtgcttcca aatcaacagc ctgcacctgc ccagatttca actcattaat agcctcaccc
    26641 atcacagtta gagaaacaca gttggcttta ttaagctgct ccttgactag gccctcctcg
    26701 atgctgcctt tttgaacagc cacctttttg ccaactaagc tatccttatt agcataatgc
    26761 ttggcatctg acgctttcac caaaatagca ttttcagttt catagtaagc ctcagaaaaa
    26821 tcatacactt tggcacgctc tttggtgtag gacaaaccag aaatcgctat atccacctta
    26881 ccagtttgca gactggataa gacattatca aaattcatag cagagagttc aagcttaacc
    26941 cctagttcat cagcaatggc ctgtgccagc tcaatgtctg ctccgacaat agtatccttg
    27001 ccgtcaacca aggccttaaa ttcaaaagga gcatagtcag ggctaacagc aaccaccagc
    27061 tttccctttt cctggatcct gtcttgaagg ctcgtcttgt tagcttggcc acaagctgcc
    27121 aaagcaaaaa cagataccat agcaagtgct ccaactaata atcgcttcat gttcatatta
    27181 taattattcc ttttcttgtt gatgaatctt attatattgc attattattc aatggtcaag
    27241 tttttattga atatttttca agcactgcga tagtctgctt aatcctgcct gtagaacctg
    27301 cggctgacag caatagccga ttctcacatg atttgcttga ttaaagcgat ttcccggaac
    27361 gaccaaggta ccgtaatcct ccagcagcct caaagcaaag gcttccatgt cctcatctat
    27421 atctagccta acaaaggccg ttgagacctc attcggtcta tggtaggagg ccctggcttc
    27481 acctgttatc cagtcctcta agatagcaag gttagtcctg ataatggctt gattgcgctg
    27541 caatagcttg tcagcatgct tcaaggctag cgaagccacc atatcatcaa aaacacctgc
    27601 acagatcatt gtgtaatctc gatataacct aagctgatca cagatggtct cagaagcggc
    27661 tacccagcca actcgaatgc ccggaatcga aaaggttttt gacatgctat taacagtaat
    27721 ccccttatca tacaaatctg ccaccgctaa aagatgatca gaggtaaagg aatgataaac
    27781 ctcatcactt agcaggtaaa tatcatgctc tctagcaata ttgatgagct cctctaaata
    27841 aggcttggtc atataggcac ctgttgggtt gttggcattg ttgatcatga tcatttttgt
    27901 gttgggacga atcatggcac ctagctcatt aaggtctggc agccaagcct gctcctctct
    27961 gatctgccaa taatcaacct ccactccaag agaagctgga atatcatata gctgctgata
    28021 gctaggatag tgagcaatca catgatcacc tgcttcaagc agtgcataaa taaccaaaaa
    28081 attggcacct gttgccccat tggtttgcaa gatatttcta gctttctgct gctgataaag
    28141 ccctgccact gcctgcttaa agtcaggaga gccttctatc cagccatagt ctaatggctt
    28201 ttgatgcagc tgctggtaaa aggcttgagg ctgctcctgt gttaagtcaa agagctcctc
    28261 aagcgttaat gaagcaatag atgagccagc aatatcgtat acagcacgtt tttcatgctg
    28321 atttagccac tcttctacac caaataccgg tagtttcata agatcacctt atttcttgcg
    28381 taatatttat tacaatatcg cataaaaata caattgtcaa atcaaaaact atcctttttt
    28441 tgataagaat catgtcctat ctaacagtta gtcctgattg gtctcgcatg aaaggctact
    28501 aaatagagca aaaatcacat aaaaagactc ccaacccacc aatcagcggg attaggagcc
    28561 tgatagctcg tatcaattca ttgatttcag atcagagtga ctatcatcac tctactatga
    28621 gccaatgact aggctaggcg gacaacttct agctgtgatc cacccattaa taccaagtat
    28681 ttttcgatcc ttgcaatccc gtaggattgg ctcagagcct cggcatatag gtccatttgc
    28741 tgctgatagc gctgcttcag ctcagctgac tgctgatagc gatctgtctt atagtcaaaa
    28801 agaacaatac gatcctcaaa aagcaggtag ccatcaataa taccacgcac tacgtactgc
    28861 tcctgactta ggctgtcttt tttcagcatc gcaaaaggag cctcgcggtg taggcgctgg
    28921 tgatgctctt gcaggagctg ccccaattca gttgtcgcaa aaaaagaggt taccttttca
    28981 atgtcaagcc ttgccttgac ctctgcgtca gctgagacaa gctgtaaggt ctgttcaata
    29041 tcaccagcag taacctgatc agacattgga atacgctgca tgagctcatg caggcttgag
    29101 ccgacctggc taggctcaac agcctttttc ttagaaaaat caggaagctc aaaggtcttg
    29161 ggcctatgat aaggctgatc tatgatatca acaccatcag tatccattag aggctcataa
    29221 agggttttaa gctgactggg ggttctcacc gtcggcagct caatggccgc ctgatagctt
    29281 gcattgagct ctgacacctt atccagcatg tctaaggcac gcgcaatgtc ctctgtttga
    29341 cggttatcct tgagatcatc tgcttgcagc agccctgagg gccttagctg accaacagct
    29401 tctggtgtta agtcactgtc atcaacaaat cgcacatcaa taaacaagtc ctccttgcta
    29461 aatgttgctg ctatcgctag tagccagtct tgaaagctca gcaatctttc tcgactagct
    29521 aaggctaagc gtccttcgga gctattgtcg gctgtttttt cctgtacctt ttccttgcta
    29581 gccttaccaa tgaggtatac ctttttttct gctcgcgtca tggccacata caagagacgc
    29641 atttgctctg ataaggtcgc caagcgtagc tgctgcttat tgagctggta aggaagagtt
    29701 tccatcgtaa ccttgagcga cgccaatttt tcttctctta gaagctcctt tacattggcg
    29761 acatatttga taccgattcc ctcatctcta tttagaatga ttggcgcctg taggtcagcc
    29821 atcgcaaagc gcttgtcgca attcaaaatg aacacgtaat gaaattcaag tccctttgat
    29881 ttatgaattg tcatgaggtt aacagcatgc ttaggccttt cgacctcaac atctgccaaa
    29941 tcattttgcg tctccagcac cttatcaatc atgccaataa agcgtgagag tcccttgtag
    30001 cctgattgct caaattggtc agcccgtata gcaagggcgt aaaggtttgc ctgagcctgc
    30061 tctgcctttg gctggcttgc tacaaagtca aagtaaaagc gatcgttaaa aatcttccaa
    30121 atcagctcat aaagcgaatg aagctttgca aattgacgcc agtctctcaa ggtcccatca
    30181 aaatcagcca gctttgtcat cagctcctga ccgatcagct ctgggtgctc gccttgtcct
    30241 ctcaagctat tgctaagctt gtcatagaag gcttgaggct gcttttgtga gctgccttgc
    30301 agtgagattc ttgccagctg atcctcatca aaggaaaaca ttggcgagcg cattaaggcc
    30361 actagggcat aatcattcaa aggattgttg atgcttctta gcgtatccag catgaccatc
    30421 acctcaactg atttgaggta attttcttgg ccaccatcag caacgagagg aatgccatac
    30481 tgattaaaga cctgaaaaat agtgtcattt cgtgtgcgtg acgaaacaag cagggtaata
    30541 tcttcaaaag caaccttctc ctcgttatag agcctgatga tttccttagc cactaagatg
    30601 acctcacctg cggagatacc atcgttagct aaggcttcct cggtgccttc ttgaacttga
    30661 tcggtgtcat agagcagcaa ttgggctcga ttgttaggat atggctgtct ttgtccctca
    30721 ctgcctgcta ccagctggtg cttgtcatca taggtaatct ctcctaaaga ctcgtccata
    30781 aggcggctaa agacagcgtt ggtgacattt aggacctctg actgactgcg gaaattttcc
    30841 tttagtaaaa tcagcttgcc atgctcggga ttgctttgat aatccttaaa cttttgattg
    30901 aagatttgag gatctgcttg cctaaagcga tagatggatt gcttgatatc cccaaccata
    30961 aaacgattat ggccattaga cagcagctct aataggcgct cctgcatgtg attgttatct
    31021 tggtattcat caaccatgac ctcatgataa tgaccttggt aagcttggcg aatatctgga
    31081 gcctgttgta aaatctcaat ggcaaaatga gctatatctg aaaattcaaa ggcattttct
    31141 tgcatttttg cagccaaata agcctctgaa aagctgatca caaaggcttg cagcacctcc
    31201 aaaagtggta agctctcctg ttgataagca aggatagtct ccaagtgcct aaatcttacc
    31261 agctgctcct gtagcgattt gaaaataggg tatttgtgac cggctacagt tatatcagct
    31321 cctgaaggaa gtaaagctgt tagctcctgt gctagctgac ctagtcgcgc tttaccgtaa
    31381 aggctgtcaa aatgcaaagc ccactcatat aagctgtcaa tcattttgag gtgcttagtg
    31441 tatttggcag ttagcttgcc agccttggtt gtttgagcgt aaccctccat gtctgtgagg
    31501 tctcgcagct gatcagcagt gtcctgcata caggctaaga gagcatctac agcttggtct
    31561 ggaatatctg taaagctggt ataggtctta gaccctcgta aaaagacctc tgccaaccaa
    31621 ctgctaggat tggcagttga ttgactgaag gcataaatgc tatcaacaat ctctctaaag
    31681 gctgagctat ccttacgacg tccagaaaaa ttctgcacca gctgtataaa ggctttattg
    31741 tcagtctgcg acatatagtc ttcaaaaacc tgacgaaaga cctcgcgctt taaaatgtcc
    31801 tgctctgcct tatcctgtat gatacgaaaa tgcggtgaaa tccctaaaac ataaccatgc
    31861 tggtgaacca atttctgagc aaaggcatcc atcgtaccaa tatcagcctg tgataaagcc
    31921 tgcaattggt cattaaggta ggccttgagc tgataatcct gagtctctgc tatagctgtg
    31981 tgcagctttt tttcaattct ctctattagc tcagtagctg cttttacggt aaaggtcgaa
    32041 ataaataagc aatcaaccgg aatacctctt agaatcttat ccaaaatgcg ctcaaccata
    32101 acaaaggtct tacctgagcc agcagatgct gatactaaga tattttgtcc actgctataa
    32161 atagcctcaa tctgctgcgc tgtccgcttg tgcgtcttat ctgataaggc ctcctcctgc
    32221 tgcaaacgag caatagcctc tggcgttaga aagccttcat caatcctcat gctttatctc
    32281 ctcattcatt cgtgtcaaga aagcctgtct cctttctttt gtcggtagga cgactaggcg
    32341 tctcgcgtac cctagatcta aatccgcctc aaagcgcgtg atggccttga gctggtcacc
    32401 ctgaacagac ttgccgtctg cggtataagg gtttattagg aaatgccctg ttttaatctg
    32461 cttcaccgca gacaaatata gctgctcatt ataagccagc agggtttcta gctcatcagt
    32521 ctcataaagt gtgttgttaa ggtgatagct gccattagcc agatattcct tggcttgggc
    32581 taaaaaaatg cccttatagg ttaactcctt gtaagccgca gctactagct gatcatcaag
    32641 tgccttaaag tcagacagac ttagccttgg ctcttgcatg tgcaggtaca tggcgccaaa
    32701 caggccctgc cccttattct ttagggcagc aagataggtc acaagctgag gactcaagcc
    32761 attgtaaaag gcaacaatgt caaataccct tgcactggat ttgtagtcca caatgcccag
    32821 cctaccatca gctagctggt caatacggtc aataacccct cgaataagca cttgctgacc
    32881 cagcgctagc tcaaaggcct cctcttgctt ggttatctgc aggccttgat taaggtctaa
    32941 gacagaggct gttgagtaag caatcccctt taggacctct aagctatatc gcccttcagc
    33001 atcagcctga taaacctgct gaaaagcgct ttgctgatta actgctgcaa tagctgcgcc
    33061 tagcttttgg tcaaaggcag cattagacct atccttggtt accaactcaa aaatacggtg
    33121 caggtattga ccatgaatgc gagcatctgg gtgaatagac tctggctctt gcagccctag
    33181 gacatatttc aagaaatact tgtattgatt gttataaaat acagtcaagg ccgatgaaga
    33241 cagattcaag ggctgctgac ttgaaaagcg ggtctcaata acctcaggtg ctactggctt
    33301 agtagtcaaa tgatgctcaa aagctggaag acttagctgc tcatcggcta gcctacgttt
    33361 caaataacga agggcaaccg tccaaaagtt tctgtcctca ctggtcatgt catctgcaat
    33421 tccctgccga ttaatagcca ccaagcgaga caagagagcc ttataattgc caatatctgc
    33481 cgctgagtgt gacaaacggt tctttccttt ttcaatgact ggaacaccaa gggcaattag
    33541 ctccttcagg taaggagaga catcatctga gctattcgtt aagcttgtag gcaggcttaa
    33601 caccagctcc tgcgtcgctg cattaaacag ggaaagtgct gtttggtgat ttttcttgat
    33661 attttcaaag ctcggcacat caaggcgctg gtaagaggca gtctgctcat tgatgcttgc
    33721 cctttcctga tcagagatca ggctggtgtt ttttgtctgc ttaggaaaat gggagcgact
    33781 caggccaatc gcaaacacaa agggcttgga atgcggctcc accagatcat aggatttgat
    33841 agacacaaca tctaaggtcg caggcactgt ccgataatgt gctgtctgca tgcccatctt
    33901 gatcagagct agacagtctg caagggtcat tttttcctga ccaaacacct gataaaaggt
    33961 ctctaaaatg cctgtgaagg ctttccaaac ctcctcgtcc ttttccctat cagtctccct
    34021 tctactgcct gctagtgcct caaaattatc agccagctga atggtcttaa aaaaggtcat
    34081 tagcttatca agtagggaag cccctagctg cttttgactc ttaaagagct gctggagagg
    34141 agtcaccaca gcaagtcgca gctgattcaa aagaggcaaa ggatactgac gtgaggaatt
    34201 tagggtaaag ggtcttgaaa atttggtgaa gccttgaata tcagcaaaga ccaagtattg
    34261 ctcaagctga tccagctctc cctcttgaaa gcgcccaaag agtcctgatt ttagtaagtt
    34321 gacaatatcc tcacgtcgcc aattgtatct gcggcctctt tctaaggatt cgacaaattg
    34381 aaccaagggg tgagcagaca tcggctcttg cttgccgata taataaggga tctcaaattt
    34441 ctcaaaaata ggaccaattt gcagctgata agacgccaca tcacctaaaa ggacaagcat
    34501 atccttatag cgataaccct gatagagctt ctcacgaata gcctttgcaa catgctcaag
    34561 ctcctctttt tgattgagcg cttgccagat cacaaccttg ctcttgtcct tggcactgag
    34621 ctgccaatca agctttgaat agtcatgatt ggcttcaaga agctgtgtta ggcgagaaaa
    34681 tgacacatca aagacctttt ctgacgttgt gtagatcggc ttggtttgaa attgctgtgc
    34741 cagctgttgg ataaacgcaa ggctcgcctc gtagagattt cccttggtaa aggctagtcg
    34801 ataagccttt tgactgatat aggctccaat aacgatttct tcacaggctt cgtttaagag
    34861 cgctagcagc tgctcctcct cagctgaaaa gcgggtaaag ccatcaatca ctaatacggt
    34921 ctgccttagc tcgtcatcta ggctcttgct tttgatagcc tcagcaagct gagccagcct
    34981 acttgactgg tcgtaatctc cttgtgcaat cagctgctca gccttggtca taatcgtgat
    35041 caggtcctct tgcttttctg gtctatcaag cgtcgttaag tcaaaggctg tcagattagc
    35101 tgcttgcaat tccttatata gctcaactaa ctgggcaata aaggcctgat ctgtccgtag
    35161 ccggtgaaaa acctttagct catcttcttg cagctgcatg agcacacgat aaaaaatcat
    35221 ggctaagcca ttatcatcta acgcttgtcg attagctgcc ttagctaagg taaaataacg
    35281 cgccatctgc tcaaagcggg tcaccgtaat agcaaaggaa ccctgctctg gcaataaggc
    35341 taggacagaa cgttcctttt caaaggatag agagttagga gcaatataaa agacacgata
    35401 gcccttatca gcataagctc ttgcctcttt gactaaaatc tctgtcatgg aatagctaat
    35461 ctctgtgtat agtaatttca taaaactcct tttatttgga cctgatacaa cgtctatgcc
    35521 tccattataa caaatcagcc ttgcttttcc cattgttaat gatctttcaa acgccacaag
    35581 aagcgctcac agcatgaaaa aagcctacca tttcacatct gctgctttgc gcaagaaatg
    35641 ataaggcttt gtcttgtata ggctcaaaaa acagactaag agctcctagt taagctgccc
    35701 tgtgcttgtc tcttgtgatc tgtccccagg cattcttttt acgctgataa ccaataaagc
    35761 tgctcacctt gataagggtt aataccgtat gaagaacaag gcattggtag atggcagcat
    35821 agattaccca agccatatca aaaagagtaa tgctactatt gttttgcaaa taaaccctat
    35881 ttaaaaacga tgtcaacgca ataagcacac aatagcaaat atagagcagc atcagtgaca
    35941 caaaaaaggt tgtgtttaat tgatggcata gcaaagacag cacaatgata ataacaccaa
    36001 atgcctcaat aaaaggagat aaaagctcaa acaaaagata cagcacatag gaaatgagta
    36061 ccgtcgcttt aaaccgacag cttacaaaaa actggagata ctttttcaag cattgataca
    36121 gtcctaaaaa ccaacgacgc ctttgccgac acaaatcctt caagcgactg ggcgcttggc
    36181 tccagcaaat agcgtctgtt tcatagccaa tacgataagg aatcttgttg ttatggcaga
    36241 aaaaatgtaa tttcatcacc agctccatat cttctcccag agtcccagtg tcataaccat
    36301 caacagcaat cgcaagctct tttttaaaca gtccaaacgc tcctgatatg attaaattcc
    36361 cagcagcctg gtctaataaa acacgagctc caaaaaaggc acaatcatac tcaattgcct
    36421 gcgcacacga aataagctga cgcggcaaat ggtagtctac gatcctccca gctgccaatg
    36481 ctactccctg cgaaaccttg accatgcccc caacagcaat gacagacgga tcctttgcag
    36541 cagtctttgc aatacgctta agcgaatcct cctgtagcat cgaatcagcg tccatgcaca
    36601 ataaataatc gtattgagca gcgttaatcc caagattgag gctatctcct ttgccgccat
    36661 ttgccttttc aagcagggtc agcttgatat gcttgagctg cttttggctt acagccttta
    36721 gagggcgtgt tgggatccgc tgattaatcg aacaagtcac cgcttctaaa tgaaactgct
    36781 ccttcaagag cttggcggta tgatctgttg acccatcatc aatgacaata atctcatagc
    36841 agtcataatc aagcatcagc aaggactcca ctgtttcgat aatggttagc tcttcattat
    36901 aggccggaac caaaatagac actggcggta aagaaacatc accaccaaca ggcgcttgct
    36961 gtcgcctttc ataaaggtga atagtcccaa caattaagga tagcagtaaa aagctcgcat
    37021 aggcaatcaa aaacgctaaa aaaagatatt gggagtattt caatactaaa aacagtagct
    37081 gcactatcat tctcctttaa catgcaatca cttgtgctta ccattcgcct tacaaaagcg
    37141 tctcaaggtc tgcttcatca aatacccgat attaaaggca aggatcgcta agcaaacgat
    37201 tatataaaaa aacaacaggt aataaatcat cttatcttct cctcttttcc tgccagacag
    37261 cctgcacctg ctgataggag gtctttaaaa cttctcttac ccttggacgc tcccagctca
    37321 acagtggata ctctaccatt gcaatgacct ttgattcctt tagcggtgca aaaccaatag
    37381 ctattgcttc aatggctaat tcctcaacac catagtgctc aaaataatca tcgtgtattt
    37441 tgtttgaagc tggatcagaa aaattgagca gctgccaggg aatcctaagc tcaatcagac
    37501 gctcgccaaa agaaatatcg gtctgcgaat caaaatgagc cgagcctcgt ttgccattgc
    37561 cctgttttaa ttggccggta gggtagcgct tcagtcctct ttttgcaatc ggaacctgat
    37621 caatggctgc aaaaatacca tcatttctca ccaccatatc aaccatagta aatcttggcg
    37681 tatgcttgtt agggggaaag acataaaagt cctttccatt aatctgccta aggtaattgg
    37741 catcagtagc atggtagcgc tcctgcacca agaggcgact gcctttgtgg tcatcaacaa
    37801 caagggcaaa atcagcaaag cgatcaaacc gagcgctaaa gccttcaata accctgctgc
    37861 ctgttttggg cgtaatgtct aagggaatga gccactgtct ttgtaagggc tgcttttttg
    37921 tcgattcaat agcaatatag aggtattttt cgtcctgatc aacgaggagc tgctgcccat
    37981 ttttcttgta ggttagagct ctagaccact catctgctgc cttttgccca tcaatagcat
    38041 gcgtccttgg agcatgctca aaggttaaga gaccataacc ttgagcctta gactgaacat
    38101 caccccaaag aaagctttga tgtttattgg ttgcaaagga ggtattccag ctcctagcag
    38161 tccaatcgtc ctgccagcta tggatcgttg caccacagca gccagacgca ataaaggctg
    38221 tgtaatctgc catcaagcgc tcgccttgat ccttttctgt caaagggctg gaagtcgata
    38281 tcatttggtc cacacctctg gctgtcgaat agccatagcc cgtcacaacc actgggacac
    38341 gatgatagct cgtcagtagc ttgacgtatc cctgatataa gggcatgcgc ttaatatccc
    38401 caacaagcct atcagtaagc cctagacggt caaatagcag ataatcccta taagccgagt
    38461 gacaatccaa gagcttatag gaagcaaaaa gaccggcctt aaccttagcg ctgggcttaa
    38521 tattttcaat cgtcagttga acatattttg ctgcctgaga ggcaaaggga tcctgataga
    38581 caaagggatc tgattgaggc gtatttgaaa agctcaccaa gtgctgccag ccatatttgc
    38641 ggctctcgta tgacgtgatt tcctccatga tttcagccag tatagcctca aaccgattgg
    38701 cctgaggtgt cgttgcataa taccttccct taaagcctac aggcttggcg tgattctgat
    38761 gattggtata ggctatcgtc ccactgtacc aatcatcacc aacaatatag ccgagtagcc
    38821 atttactcat atcctgatca taatgctgaa gccctaaatc cgaatgccag atccgttttc
    38881 tcccatgaat cacatcaaca ctagccctag cttcccttaa cagagtgcct aaataagcct
    38941 tatctaaggc gctgatagaa gaattgtcat gataagcatc tattctaaag ccctgtaata
    39001 ggtacagagg atgacttgct ctgtcattgt agcgtctcaa agcatggtaa aaagtgacgg
    39061 gcataataac ccttaccctg atcgtatttg cacccatagc tgctatttgc ttgaaccacc
    39121 tatagtaggt tttctcatca acgctaaggt ctcgtcgacg atagcctgct atggaactct
    39181 ccacatcaac acccttgatg agataaggag atcccttttg atcatatatg cgcttgtcct
    39241 tggtgtaaaa gactgtccga atagctgact ggttagagac cggcaggtac aagcgaccat
    39301 caatatcaca acaataatag ctcaagccaa tcacagacaa gagcaaacca acaaagatta
    39361 aatatttctt catcactacc tactccaata atgtattggt atttttagac ggtgcactgt
    39421 actgatagag cgtctcaata tgcttatcca gccatcgccc acgacgtcta ataaagtcct
    39481 ttagttgctt aacagaggcc tcatagctac tgtagttacg actggctggc acaaggtaat
    39541 tagtggcatc gcttcttgat ggcactgtaa acacatagcc ccacttatga taattgcgct
    39601 gaatagccgg acctaaaaaa gcaaccgtag catcaatata cttgatcaaa taatccgttg
    39661 ataaaacatt ctgtcggagc tgatgatacc ttgtgaccac cagcttaaca aagctaggat
    39721 cctttagcag catgcaaaac caaggagcat ctgatagggt aaagtccgcc tcatcataag
    39781 gagcctcaat ctgattatca aaggcgttgt taaaatccca gaccaccagc ttgagcttat
    39841 cgcgcaaatc cttataaaga taggttgaaa acttcccagc atcaatattt ctaaagaatt
    39901 cattgataat aaaatagtct gcaaaggact cttggtccag ataatcagtg tattgcttta
    39961 aatcataaga atataggagc ttttcgatat gactgatatc cttttcaata aactgctttt
    40021 gcttaggcgt cagacggtgc aggcttgggt atttaatgtc taaagaggac agacctgctt
    40081 gattcgtata ggatacgtaa tgatcaagag cctgcttagc cttgtgtctt ctatcccaaa
    40141 caaggatata aggcgtttta tcagattttc tatcactttt ttcgatgttt accctatgcc
    40201 gcccctgctc aatactctcc acagccaaat acagaccaca atactgatga tccaccacta
    40261 actcgcaata cctgacgtta ggtgcatagg tcatgatctc accggcaata ttgtagctaa
    40321 gataatttcg gactagggtc cgatctaaaa aaggaccatg cagcacccac tcagactcct
    40381 tggacatgcc agccagcgag actgcctttg gcttagctct tttattgata aaccttagct
    40441 ttaaggattt cttgtcaaaa tgacgtgacg aattgcccct ataagcaatc aatgctgtca
    40501 aggacaagcg cggagactca gacaggctgt gctctctatc tagctgatca cgaagcgaga
    40561 ccgtcgtttt aatggttttt tgccgctttg tctctccctc gtattccctt tgctctggaa
    40621 tctgctgatg atgagtgtca atgctaataa tcggcaaatg agagctaaac tccccagtgc
    40681 ttctggagct ctttttgacc gtctgcaaat ggtgatgaat acgctttgca gaggtcttag
    40741 gaaaaccgat accacaaata gcagctagca agagacacac cagcacaatc acataaatcg
    40801 tcttttcttt catttacgtc aaccagttat gtcatcgctt tgactaacaa tattaaaata
    40861 atcaactcgc cccagctgat aaacagcctc agttaacgga ttagcctgct gataggtgct
    40921 gtcataatcc tttcttgaca gctcaaagat catctcaata tcatcagacg tggtgttttt
    40981 cacgctctgg atcgccttac ccgaaaagta gttaaacact aaccgctcca gctcaatttc
    41041 catttgctta tcacagcgaa caatcaacaa cagtctattg tcatttctga cagctcccat
    41101 aagcaacaaa agcataaaga tcacgctgct accagttgca gcgacagtat aatcaccaac
    41161 accacagcaa atcccaacca caatcgtcca aaaaatatag actgtatctc tagagtcttt
    41221 gattgctgtc cgaaaacgca caaccgacag cgcaccgacc ataccaagag acaaagcaac
    41281 attatttccg ataactgtca tgacggttgc tgttaagacc gtcaaggtca tcaacgaaac
    41341 attaaacttc ttgctatagg cagtcccagt gtgggtatag gcatatgaca tataaatcac
    41401 aatacttaac aaggctgcag caacaatatg cagcaaaaca tcttgaaagc tcaaggtccc
    41461 acgctgttca aagacatgtc ttaataattg tttcatctta atatctctcc taaaaacgat
    41521 aatgcttgct gatagctctc cccatgcaat acttgcttgc acttagctcg ctaccattaa
    41581 cagactccaa aagctttttg atataagaca acaaaaagcc attatacttg acctccaaga
    41641 tgaccaaata gggatctagc aggtaattct gaggcagatg atctgaaaaa atatcagcat
    41701 tggtctcaga cccgataata tgatgatcaa aggtaatgcg aatattgttt tcctttgcca
    41761 caaatgcctt gcgctggtat tcgatcactg tttttggctg atagagctgc attgacatgc
    41821 gactatagca ttcagcagca aagcgatcag gataagtcag caatatagac ttgtctccct
    41881 taatcaacaa ttgagcgtct gctctggtca acctcagaga tcgctttttt tgattgctcc
    41941 cttgcttttg cttcatctcc aacttagcaa atgagctctg actaccgtaa ttgcgcaggc
    42001 gaatttttcg cctaagctca ataccgtcct ctttttcctg ccagtcaacg tcctccaaag
    42061 aatcaaaata caaggatcga atcacatatc cctcactaga gctatgagca tctagacgca
    42121 agagcttgga aaattcatgc gataagcgat aataatcctc aatggtaatc aaatactttt
    42181 tttcttgacg caatacctca ttcacgccag tgtcctcctt tttcgtctgt aagcaatgcc
    42241 ttaacaccaa gctgcctgta acagcagcca acaaacctgt ctcataaata agtcagggca
    42301 aataaggtga ttgttggctc tacaagagtc aatcacctgc caaaatagta aatcctgcca
    42361 tctgttgaaa taatataaac cagctgatcg tcttgattgc aagacaggcg cttttgtgac
    42421 tgatctagct gtctgctgct aatatcagtt gcattagcct ccttgagcat ggcctgcttg
    42481 agctgttgct ggatttttct ggcttgcagc tcagaaatct caaagctgcc attaaccttt
    42541 tgagccttgt gcttgtagac cagtgccaca tggtctttag ctgttgtcct agcagtcgac
    42601 aggagccctt ctttgttgag ctgagtatgc tctcctacat caatggcaac atagtcatag
    42661 ggtgcccgta tccggtgcgc tgttagtatt gaggacaaaa tccctgtcac aaggcagatg
    42721 cttatcgtag ccactatcat ctgctgccgc tgcttacgaa tgaaccttga aaaagcacag
    42781 acctccgcct gatattcctg aagctcttct tcaaccttac tgtaatcctg tctaagatca
    42841 gccaagtcag tctgacagtc cttgcagctt gtcagatgag cctcaacaac cgctctacta
    42901 taatcactca acgtatcatc tacatataat ggcaacaaat cctggatcaa ctcacaatca
    42961 tacttcatag ccatactcct ctcgtaattg tcttttaata tgttttcttg ccctaaagac
    43021 aagaaccttg gcagaggata ctgtgatgcc aatatcctta gctatttttt cataggaatc
    43081 tcccgaataa atcctcgcca gaaagacagc ctgcattttc tctggaagat taaaaataat
    43141 cgttagtgta atctctaaca gctcccttct tgctatctta tcaagtggtt catcatgccc
    43201 tttagcatca acgatttcta agctttccat cgacatattc tcatattttt tctttttaat
    43261 ttctgtaaag aaggtgttct ttgcaatggt aaataaccat gttttgattg aactatcccc
    43321 actaaattta gcaatattac gataagcctt tagaaaagtc tcttgagtaa tatcatctga
    43381 taaactattt tgataacagc acagcttatt tacaaaccta taaacatcat ctttatattc
    43441 taaatatatg tcctcaaatt ccaacagctt gtctcctctc aatacaccct taaccattag
    43501 accgtccaat ctgccaaaag ttacagatta atttaatttt tagtataagc tgtcatcaag
    43561 tcagataaat agtaatgatc tatcatctta ttattgactc aaacgacaaa ttatattgca
    43621 ttttagtata agctgtcatc aagtcaggta aataacaagg acatatcatc taacatttga
    43681 tccagacaaa aaagacctga ttctgtaata tacagaacca agtctttctc aatagacatt
    43741 gactagatga ttgatttata gcgacatagc tagataggct atgacttacc gtcttttgga
    43801 tttggagaca agcccgccaa gacctgccaa gataccactg ccagcaagag ccaataaagc
    43861 atctagctga ctagtgcctg ttttagggag agtcttagct gagaactgag aaacctctcc
    43921 agcagtctga gcagcaacta atttctcctg atgatgggct gcttgatcag tcattgcacc
    43981 taaagtcccc ttatcagact gggacgccct aagacggata atggtagctg ttaagcctga
    44041 tagcttgacc ccgtccttgg ttagcacaac cccctcagga cttgccagcg cctcggtgcc
    44101 tgcttgcttg gcatcgacga taacctcacc agcaagaaga gcctgaaact caccagttag
    44161 cctaatggta cggtcattgc tatcagcatt gacaaagaca gcataaacat caccattgct
    44221 tgctgttgtc tgataagcaa tcaccaaatc ctgtgccttg atcccatgct catttggaac
    44281 agtgatcagc ttgaccttct ggtctatctc agccttactt gccaagcgaa aggcatctgt
    44341 cgaacggcgc agcgcaatca atcccttagt aaaggcctga cttgtcgtgc tttcagggta
    44401 gcgctctgta tccgttgcct ttgcccagtc aaaatgatta atggcatctg tcgaatcata
    44461 ggaatcatga ataaagtatg ggtattcaaa tggtgttccg tcctcattga ccaagaggtg
    44521 tgatttattt ggcaccttgt catcagcgac cttgccctta taggcttcgt ccttaaattg
    44581 ctttgtacga ccatattcct gaccagcatg taggaaaggg gtgccttgag aggttagcac
    44641 caagaggttc cctaggcgca agcgacgatg aatctctgcc gcatttgctg caacagacgg
    44701 atccttttta atagactggg cgataatatc aaacaaggtc aggttatcat gtgcagcgat
    44761 atactgaatc acatcacccg gatcatcagc caaaaagtta gtcggctgag ccttgatatt
    44821 atgaaaaatg gtcatgatat ccctagcacc gcccgtaata aaggctggag agccttcatt
    44881 tggaaagcct gatttgagct gattgcgaaa atcatctgag aaggaggcaa cggtatctgt
    44941 ctgtgacatc cagctttggt ccgcaggctg ctcaggcatg tgctcatcac cctgataggt
    45001 gacccagccc tcaccaagca tgatgatatt cggattaagt gccttagctg ctaaaaaggc
    45061 tttttcaata gctgctgcat catggtcccc catcatgtca aaacgaaaac catcaacctt
    45121 atactcatcc accagataag taatcgaatc caccaaaaca cgacgactca tgtaatgcgt
    45181 tgtcccaagt cgtccaccac caaatgaggt cctagcagtg ccatcagcat tcataaagtg
    45241 ataataattc ggctccaggt cctcaaaaat atcaacatta gctgtatgat tgtagaccac
    45301 atcaaggata acccccatac cacgcttatg gatttcatta acaagctgct taaattcctc
    45361 aatgcgctta gctgggtcgg ttggatcagt cgaatacata ccagtcaagg caaaatagct
    45421 ttgtggatca tagccccagt tgtaattatt atcacttgag ctgtaggtca gcatacgctc
    45481 cttgttggcc aattcgttga caaaataata gctcatcaca ggcagcagtt gaacatgcgt
    45541 aataccaagc tccttgagat aatccaactt ttcaacaaag gcagcaaaag tcccaaattg
    45601 agcctttaga tcattagcaa tcgcctgatc tgaggtaaaa tcacgaacat gtgcctcata
    45661 gataatggcg tcctcacgct tatgaaagcc cttaatatca gcaaaggcca gctccttatc
    45721 cccaatagca gcaggatcaa caatggccgc cttagccacc ttataggacg ggtctgtctt
    45781 agcaagctcg ctgttccatg ccgctaacga tttggcataa gggtccagca caaggacaga
    45841 cttgccattt ctagtaatct cataatgata gaaatagcct ctataatctg aaatcccaag
    45901 tccgctatct gctgatagag tgattgacca ctctccctta tcaccctttg ctagagcgag
    45961 attaccaatc accttggtct gatcagcctt atcatacaaa acaagtgaca ccttatcagc
    46021 acttggtgac caaatcgtca gatcaacctt agcacctgct tctctcacac gcgctcctag
    46081 ctcaccgtca taagcataca ggctatcctt gtattgccaa tttggcctag cctggaagct
    46141 ctcatgatga aaggtcaccg tataagtggc cactgcttga ctaaaatcac ctgtgatgac
    46201 agccttatga gtcttttcat ctaaggtgat atcagtaata gcaactgctt ccttactgtc
    46261 agtgctgatt tttaattctt ttaaaaggct ttccttatcc acatctgcta gagtcgtaaa
    46321 gctcgcctca atactgcttg ggctgacctg ctgagcaccg attaatctaa ctgtattaac
    46381 aaaataaggg ttcgtataaa tggttggatc ctcgtctttc aagaaaattt gggtgtgatt
    46441 ctttaaatct ttaaaaatat aatcattggg ctgaatttta acagcgtcac ctgtctgacg
    46501 ctcatctagc aagagaaagc ctagctcatt ggtatcagct agcttgacat ctatataagc
    46561 accatatcga ccgacctgct taaaatcaat accatctggc caagcgccct gctgactagt
    46621 cattgacgca tcagcacttc cccaaagcca gagcgatttg ttgtcataat ggccatcact
    46681 gcgataataa ttgatacgga tatagccctg agccagcggc cgatagtaag acagctcctg
    46741 gccatcaatc cagacctcat tcatcttagg gctgagaagg tctatggttc gatcgcccgt
    46801 cagattgtct cccttagtgt tattgatcaa aaagctaacc ttattggctt gattggctga
    46861 aagcttaacg tccatgtaat agccatagtc atctgtcttc gctagactaa aattggtagc
    46921 cccagtcggc cagcctccca gctgatcaga tggtgtctca acatcgtccc acacccaaag
    46981 accaagcgag gataggtctt gagctggcag ggtcttgaaa tgcagccgca aggtctgctc
    47041 cgctatcggc tcctctgagc ttgtagcttc tggtgtctct agagagctgt ctgtcgtaac
    47101 agacactatc gatgatgaag gctgagactg gtctgtagtt tcctcatgcg cctgatcctc
    47161 tacaagaggt acagctactg gctgaacttc cttgacagta tcagcattga cagcagctga
    47221 caccttagtc acatcagaaa taccagcaat atcactaatg tcagtagctt ctggtagctc
    47281 atttgagcct tggtcagcag cctctgactt gaccatgacc gcaccatcag caggctcaac
    47341 actcgtcaga ctctcagctg ctgctgtgat ctgcccacta gctgtcccca aagaaaaagc
    47401 ggttgcaata gctaccgaag ccactccaag cttaagctta cgaatgccaa ataattgacg
    47461 ctcttcaaac agcgcttgat tttcccctaa ccttttcatc attcctccgt ccttatcctg
    47521 atagttatta acaccttaag tatacaaaag aaatcacaat agtgcaatcg ttttctttat
    47581 tgaaaacaat gatatttatg aacaaattag acaagaatca acgcaagcga tttccttact
    47641 gataaatacc tgctcccctc actaagacca gcccactgca aagcagaaaa gtagcctaaa
    47701 gagccttagt aacagataaa tgagcttaat gttgcttcat caactagctg gctgcaaccg
    47761 ttttgctctg atgtggtaac gtcttgtcat catgactaag cttgacaaaa aacgctgtta
    47821 gttacataat caacggtgct tggtagcctt ccattactcc tttgattgtt ataccctaat
    47881 gatacacaaa acctcagttt ttatagtaga atattacact ttgttttgac aaagatgttt
    47941 aatcttgcta aaataaactt atcaatgagg gagtaccaat gatgacattc gaattcacat
    48001 cgttattcga tttacaaact gcttttccaa cagagcaggc ttgcataaat catttagaaa
    48061 atatcacttg gggtgacgtg gtgatcagcc cttttgacgc tacctcaaag gtctataaat
    48121 gcaagggaaa taaataccgt tgcaagaata cagggaagta tttcactgtc aaaacaggta
    48181 ctctttttga taatactaag attaagctac aaaaatggtt tatggcaatc tggcttgtga
    48241 cttctcacaa gagaggaatc tcctcagtgc aattatcaaa agagattgca gtgacacaaa
    48301 aaacagcatg gttcatgtta cagcgtattc gtaaatgctt tggctctgaa aactgagatc
    48361 cacttggtga cgtcgttgaa gtagataaaa ctgatattga tggtaaaaat aagaaccacc
    48421 atgatcctaa gaaggcaaaa acgttcaaga accatccttc tctgaaagat aagtcggcag
    48481 ttattggaat ggtgcaacaa aaaagtaagg ccaacgctca tacaatactc gtgattactc
    48541 tgatagtcgg cgttttatct tttatcagct aatgctgata tgcgaacaac ttataaggag
    48601 ctgatcaatg gttaaacatg caaaaactaa cctacacttt gaattagaaa gatctatctc
    48661 tcgcaaagtt gatagtaaat tgatagccta tcaagtcagt ctttcagatg gcttttatga
    48721 caaatacacc aaattatggg ataaaaccta ttcatttgat tttgtcatca accatcgtgc
    48781 gttttatgct cagttgacca aaagatgtgt ttacgatgtc cttttgcaaa ctttggaaaa
    48841 aatcagtaga aaagccattg caaagcaact agcagagctt gaagccttgg ttgatgtttc
    48901 ggaaagtaag gaagactttc agatattttt cgagaaaaaa tacaaactat catttcctga
    48961 tttgaagaat tgtgtttatc caaagaaaaa ggaactttcc gattttgatc aaaacctctg
    49021 gatagctcta cattataacc ctagaaagga gagggataca taatgacaac atggtatgat
    49081 tacatggtaa gagccagcga acactctgga agtgatggag acctctggtt tcgttacctt
    49141 tacaaggtta tcaaagacaa agaaaccaaa ctaactactg atgatgtgga gcagttatta
    49201 aaaaatccga atctaactcc ttttcagaag gtaactctgc aagatgcttt aacagaaggt
    49261 acgcatacaa gagagcatgt tttacaggca aaccgtaaaa gtcagccaaa ggatattttg
    49321 aaactcttta gagagggaaa ctatggataa aaaaatctta ttcaaagctc tgaatacaga
    49381 actagctaaa gaaaatatta gccttgacat tatctgtgtc ggtggttttg tccttgaata
    49441 ttacaatctg cgaggaacac aagatatcga tgccttttat caagaaggtg ttaacatcag
    49501 gcagatgatc aaaaaggtgg gagatgagtt tggcgttaat gaacctgatg agctttggct
    49561 taataattca gttgccaatc ttaatagaat accacctaaa acgatttgtg agacagtatt
    49621 tcactattct aacctaattg tccttgtccc acccttgtct tatattcttg gaatgaagct
    49681 agaaagcgga cgagataggg atagacaaga tgccggagac attattaagc tagctaatat
    49741 ccgttcccct aaaaaactta tcaatacact tgaagagtat gattttcaac ctgatatttc
    49801 aatgatttta gaagtctttg aaatagctta tggcatggaa tggttagcaa actatatgac
    49861 cgaacaccca gaagaattta ggcattatta aaagacgatt tctgtttgga agtcgccttt
    49921 tttgatgttt ttgaaaacac cttgagatta gtctaaacta atctccataa gcaaaaaaca
    49981 gcttagcccc gtctgggagt aagctgtttt tgctgtaatg tatgagataa ttaggctaac
    50041 atcaatcatt acataaaggg aataaagggt taatgtttct tgcgtttgcg tgatactaca
    50101 gctacgccta gacttgccaa tacggcaagg gctgctgctg taaagaatgg agctgttgct
    50161 tctcctgttg acggaagctt gtgttccatt gctttaggta ccgctggttt atctcctttc
    50221 tgtgcttc
//
LOCUS       DARYLD010000007        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYLD010000007 DARYLD010000000
VERSION     DARYLD010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TU651_000339"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TU651_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL0896375.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TU651_000340"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TU651_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TU651_000341"
     CDS             1286..2599
                     /locus_tag="TU651_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0896376.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGCNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TU651_000342"
     CDS             2700..3587
                     /locus_tag="TU651_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0896377.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TU651_000343"
     CDS             3600..4430
                     /locus_tag="TU651_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0896378.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TU651_000344"
     CDS             4446..4901
                     /locus_tag="TU651_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL0896379.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TU651_000345"
     CDS             4926..5576
                     /locus_tag="TU651_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL0896380.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TU651_000346"
     CDS             5605..6525
                     /locus_tag="TU651_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL0896381.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TU651_000347"
     CDS             6540..7424
                     /locus_tag="TU651_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0896382.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TU651_000348"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TU651_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TU651_000349"
     CDS             complement(7738..8562)
                     /locus_tag="TU651_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL0896383.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TU651_000350"
     CDS             8791..9564
                     /locus_tag="TU651_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL0896384.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TU651_000351"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TU651_000351"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL0896385.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TU651_000352"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TU651_000352"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL0896386.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TU651_000353"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TU651_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL0896387.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TU651_000354"
     CDS             12390..13052
                     /locus_tag="TU651_000354"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL0896388.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TU651_000355"
     CDS             13045..13677
                     /locus_tag="TU651_000355"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL0896389.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TU651_000356"
     CDS             13679..14950
                     /locus_tag="TU651_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL0896390.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TU651_000357"
     CDS             14940..15878
                     /locus_tag="TU651_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL0896391.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TU651_000358"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TU651_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL0896392.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TU651_000359"
     CDS             16830..19334
                     /locus_tag="TU651_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL0896393.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TU651_000360"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TU651_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL0896394.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TU651_000361"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TU651_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL0896395.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TU651_000362"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TU651_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL0896396.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TU651_000363"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TU651_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL0896397.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAHL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TU651_000364"
     CDS             24977..25831
                     /locus_tag="TU651_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL0896398.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TU651_000365"
     CDS             26041..27237
                     /locus_tag="TU651_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL0896399.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TU651_000366"
     CDS             27660..28181
                     /locus_tag="TU651_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0896400.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TU651_000367"
     CDS             28257..28628
                     /locus_tag="TU651_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0896401.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TU651_000368"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TU651_000368"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL0896402.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TU651_000369"
     CDS             30244..31902
                     /locus_tag="TU651_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0896403.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TU651_000370"
     CDS             32071..32985
                     /locus_tag="TU651_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896404.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TU651_000371"
     CDS             32995..34026
                     /locus_tag="TU651_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896405.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TU651_000372"
     CDS             34038..35084
                     /locus_tag="TU651_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896406.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TU651_000373"
     CDS             35084..36019
                     /locus_tag="TU651_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0896407.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TU651_000374"
     CDS             complement(36648..38330)
                     /locus_tag="TU651_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL0896408.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TU651_000375"
     CDS             complement(38332..38562)
                     /locus_tag="TU651_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL0896409.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TU651_000376"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TU651_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL0896410.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TU651_000377"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TU651_000377"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL0896411.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TU651_000378"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TU651_000378"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL0896412.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TU651_000379"
     CDS             41002..42030
                     /locus_tag="TU651_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL0896413.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU651_000380"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TU651_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL0896414.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TU651_000381"
     CDS             complement(42888..44060)
                     /locus_tag="TU651_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0896415.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TU651_000382"
     CDS             44186..44716
                     /locus_tag="TU651_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL0896416.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TU651_000383"
     CDS             44761..45348
                     /locus_tag="TU651_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL0896417.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TU651_000384"
     CDS             45452..46174
                     /locus_tag="TU651_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0896418.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TU651_000385"
     CDS             complement(46216..46515)
                     /locus_tag="TU651_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL0896419.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TU651_000386"
     CDS             46913..47500
                     /locus_tag="TU651_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896420.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TU651_000387"
     CDS             47639..>48181
                     /locus_tag="TU651_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0896421.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13642 a         9420 c        11268 g        13851 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct gcaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcaca tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctaca aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga cgaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYLD010000008        47138 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYLD010000008 DARYLD010000000
VERSION     DARYLD010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47138
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            544..759
                     /locus_tag="TU651_000388"
     CDS             544..759
                     /locus_tag="TU651_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0896422.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            756..1532
                     /locus_tag="TU651_000389"
     CDS             756..1532
                     /locus_tag="TU651_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL0896423.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVLGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(1601..2857)
                     /locus_tag="TU651_000390"
     CDS             complement(1601..2857)
                     /locus_tag="TU651_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL0896424.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(2943..3902)
                     /gene="nrdF"
                     /locus_tag="TU651_000391"
     CDS             complement(2943..3902)
                     /gene="nrdF"
                     /locus_tag="TU651_000391"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0896425.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(4047..6206)
                     /gene="nrdE"
                     /locus_tag="TU651_000392"
     CDS             complement(4047..6206)
                     /gene="nrdE"
                     /locus_tag="TU651_000392"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0896426.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(6227..6445)
                     /gene="nrdH"
                     /locus_tag="TU651_000393"
     CDS             complement(6227..6445)
                     /gene="nrdH"
                     /locus_tag="TU651_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL0896427.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            6867..7130
                     /locus_tag="TU651_000394"
     CDS             6867..7130
                     /locus_tag="TU651_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL0896428.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            7135..8868
                     /gene="ptsP"
                     /locus_tag="TU651_000395"
     CDS             7135..8868
                     /gene="ptsP"
                     /locus_tag="TU651_000395"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL0896429.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            9070..10497
                     /locus_tag="TU651_000396"
     CDS             9070..10497
                     /locus_tag="TU651_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0896430.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            11150..12364
                     /locus_tag="TU651_000397"
     CDS             11150..12364
                     /locus_tag="TU651_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0896431.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            12460..13029
                     /locus_tag="TU651_000398"
     CDS             12460..13029
                     /locus_tag="TU651_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0896432.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            13030..14982
                     /gene="gyrB"
                     /locus_tag="TU651_000399"
     CDS             13030..14982
                     /gene="gyrB"
                     /locus_tag="TU651_000399"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL0896433.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            15131..16855
                     /gene="ezrA"
                     /locus_tag="TU651_000400"
     CDS             15131..16855
                     /gene="ezrA"
                     /locus_tag="TU651_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL0896434.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            17227..17508
                     /locus_tag="TU651_000401"
     CDS             17227..17508
                     /locus_tag="TU651_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896435.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(17693..18148)
                     /locus_tag="TU651_000402"
     CDS             complement(17693..18148)
                     /locus_tag="TU651_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL0896436.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            18379..19686
                     /gene="eno"
                     /locus_tag="TU651_000403"
     CDS             18379..19686
                     /gene="eno"
                     /locus_tag="TU651_000403"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL0896437.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(19822..20058)
                     /locus_tag="TU651_000404"
                     /pseudo
     CDS             complement(19822..20058)
                     /locus_tag="TU651_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20267..20488
                     /locus_tag="TU651_000405"
     CDS             20267..20488
                     /locus_tag="TU651_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL0896438.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            20490..20750
                     /locus_tag="TU651_000406"
     CDS             20490..20750
                     /locus_tag="TU651_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0896439.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            21403..22008
                     /locus_tag="TU651_000407"
     CDS             21403..22008
                     /locus_tag="TU651_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0896440.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            22476..25256
                     /locus_tag="TU651_000408"
     CDS             22476..25256
                     /locus_tag="TU651_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0896441.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYPDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(25678..25815)
                     /locus_tag="TU651_000409"
     CDS             complement(25678..25815)
                     /locus_tag="TU651_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0896442.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      26059..26177
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            26175..26681
                     /locus_tag="TU651_000410"
     CDS             26175..26681
                     /locus_tag="TU651_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL0896443.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            26778..28736
                     /gene="ligA"
                     /locus_tag="TU651_000411"
     CDS             26778..28736
                     /gene="ligA"
                     /locus_tag="TU651_000411"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL0896444.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            28749..29771
                     /locus_tag="TU651_000412"
     CDS             28749..29771
                     /locus_tag="TU651_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0896445.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            29780..32080
                     /gene="pulA"
                     /locus_tag="TU651_000413"
     CDS             29780..32080
                     /gene="pulA"
                     /locus_tag="TU651_000413"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL0896446.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            32227..34106
                     /gene="glgB"
                     /locus_tag="TU651_000414"
                     /pseudo
     CDS             32227..34106
                     /gene="glgB"
                     /locus_tag="TU651_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            34173..35312
                     /locus_tag="TU651_000415"
     CDS             34173..35312
                     /locus_tag="TU651_000415"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL0896447.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            35302..36435
                     /gene="glgD"
                     /locus_tag="TU651_000416"
     CDS             35302..36435
                     /gene="glgD"
                     /locus_tag="TU651_000416"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL0896448.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            36432..37862
                     /gene="glgA"
                     /locus_tag="TU651_000417"
     CDS             36432..37862
                     /gene="glgA"
                     /locus_tag="TU651_000417"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL0896449.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            37881..40277
                     /locus_tag="TU651_000418"
     CDS             37881..40277
                     /locus_tag="TU651_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL0896450.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            40619..40816
                     /locus_tag="TU651_000419"
     CDS             40619..40816
                     /locus_tag="TU651_000419"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL0896451.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            40850..41566
                     /gene="atpB"
                     /locus_tag="TU651_000420"
     CDS             40850..41566
                     /gene="atpB"
                     /locus_tag="TU651_000420"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL0896452.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            41584..42078
                     /gene="atpF"
                     /locus_tag="TU651_000421"
     CDS             41584..42078
                     /gene="atpF"
                     /locus_tag="TU651_000421"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL0896453.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            42078..42614
                     /locus_tag="TU651_000422"
     CDS             42078..42614
                     /locus_tag="TU651_000422"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL0896454.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            42630..44135
                     /locus_tag="TU651_000423"
     CDS             42630..44135
                     /locus_tag="TU651_000423"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL0896455.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            44153..45028
                     /locus_tag="TU651_000424"
     CDS             44153..45028
                     /locus_tag="TU651_000424"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL0896456.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            45196..46602
                     /gene="atpD"
                     /locus_tag="TU651_000425"
     CDS             45196..46602
                     /gene="atpD"
                     /locus_tag="TU651_000425"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL0896457.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            46615..47031
                     /locus_tag="TU651_000426"
     CDS             46615..47031
                     /locus_tag="TU651_000426"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL0896458.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        13402 a         8974 c        11054 g        13708 t
ORIGIN      
        1 ataatattca tctaaattat ctttattttt aattcaaaaa tataagcaat tgattcacat
       61 aaacaaattg agacgaacag tagattgtag ctatatcaca ggtgagatag taatgatcgt
      121 gcgaaacaat aaactgattt ttccatgcgg gatatttgtt atcagtgagt tgaatggaac
      181 tagcagctat tgttttattg ttagtcatct agtgttttta aggtgcttat tttctgttac
      241 aacagtgatg acaacaggtt aagctaagtt cgatggagct tggtttttta ttgttacaag
      301 aaagctcata gatggtgatt gcattctttt atcatatgac aatgtttcta tttttgacaa
      361 atattattgt caaaaagtaa atgatctgtt acactggagt tggactcatg aaagaaaaaa
      421 gtaatcagta ggataacaat aacaaagcta ttttaagctt ataccattgt gtcaatggat
      481 tgttgccgga aatgactggt gctttctgtt caatcaggag acagcattta ttaggagtga
      541 agcatggctt ataggttgag aaatcggctc aaggagctac gagctagaga tggcattaat
      601 cagacgcaga tggcagcatt agcaggtgtt tccaggcaga ccattagcct cattgagcga
      661 aatgaataca caccatctat tattattgca atgaaaattg ctaaagtatt taatgaacca
      721 attgaacaag tatttagctt agtggagggc gagagatgaa agcttttatg acggaaaagg
      781 acagtacgtt ggtgagaata cttaagtcat tactgcttgg atcagggatt ggcttagtgt
      841 taggtggcct tgttggtttt ggtttagcta ggtttaacat attagaaaat ggctttccga
      901 tatcagaaga agacaccata actggaataa agtggggaat gagacccctt gttatcgtgc
      961 ttatgctgct gagcatttat gatatttatc aagttgtcaa agaatatgct agatatgtca
     1021 agctaagcga tgatgaaaca gaggagctgt accgttacat taatcttaag catgcctatg
     1081 ctttaggatt tagcgctatg gctatggtct tgaatatagt cgttttttct ttgggatata
     1141 gggtgcctat tgctaataat gctagctatc ttggtttgac ttttcctatt tacgaggctc
     1201 tgatgcttgt ggttattagt gttctccatg cttatatttt gaaggtttat actcggattc
     1261 gcggggtcaa gatgacgctt gctcctacct taaaggaatt aaagcagaat atcttacaac
     1321 aggacgaggc agaattgcag gctaattatc aaatgtcttt tgaggttgtc ttgggcctta
     1381 gtggctttat attaccaggc atttacgtaa tattattgct tttatctatg atttttcaaa
     1441 gggttgagct gaccggacta atcattactg ctagtattca cctctatatt ctggtgaaat
     1501 cctttaaatc agcacatgat ttttataggt aaggcgtaag gttttaccta ctcaagaatt
     1561 gttatacagc aaaaaagctt tgataagcca ttactggcga tcaaagcttt ttgtgtttgt
     1621 tgaaaaagag gcttttttga aagagctgtt ggctgagata gcttgtcaaa cctacaattg
     1681 caagcggcac aaggctaatg agaggttgtc cggtaatttc aatgagaaaa agaggagcag
     1741 taagaggtat ctgattaatg attcccaaaa agagggtcgc tccaatgaca atggccaagg
     1801 gaagtggtac agagagataa cctagctgat tgctaaggct tgccagtagc aagccactag
     1861 ctcctccaag catcatagaa ggagcaattt tgcctccttt agctccagag gcaaatactg
     1921 catagacagc agctgcttta cttagtaaga gcgaggcggt ataagatagg ctgacatcat
     1981 ggtgtagcag caggaggaga ccggccttgc cattgcctaa aatctctggg aaataaaggc
     2041 ttaaacaagc actaaagcca aaagccccta agacacgagg gataaaccat cggctcttag
     2101 gctttgcctt tggtgcgttt tggagcagct gctggtagca aaaggccaga aatgctaaga
     2161 tgggactggc aatgatagcc caaaggactg ttgtcagttg ccaggcttgt gggagaatga
     2221 gatactgtat gtcctgatgt ccgcttagaa caagcacact ttgaacagca gtaaaggcag
     2281 ttatagctgc cgcgtaaatg tgtttaactg agcatttttt gacaatagcc tccatgataa
     2341 agacaatcgt agctaatggt gcctggtaaa cagctccaag ggcagctcct gaagcacagg
     2401 ctaaaagcaa tccttgctct gctgctgatg cgtttatagc tttattgcaa gcggcagtca
     2461 gtgccacagc aacctcacgt gaagcacctt cacgaccgac aggtgctccc atggagacgg
     2521 ttattaattg cagccagcca tgacaaaatt gtgtccaagg gctgaaatcc ttttgctgac
     2581 tgagtgtttg ttggataggc tgaataggct tggctttttt agcaagtagc tgccagccga
     2641 gaccagcaat agctccagcc aacaatagag ataaaaaacg cctttctgga gctaccgttg
     2701 caatcatggt gctaaaagac ccagattggt atccaaagct aatagcctgt atgaaatgaa
     2761 tggcttgagt gagcacgtaa gccaccacac cagcaatcac accagctacc accagttggc
     2821 ccgtccatgt taagaaagta atcaatcgag taatcatatc ttttattata gcagataaaa
     2881 agagcctgag actactcagg ctccaaaata tagataaatc caatcttcat gagaagctgg
     2941 acttatagcc cataattgta atcgtcatca gtcatagctt caacagtacc aagaaggtag
     3001 ccattaccaa cttgagagaa gaaatcgtgg tttgacgtgc cggttgaaat accattcata
     3061 acgattgggt tgacatcatt ggcagtgtct ggaaaaagag ggtcctgacc aaggttcatc
     3121 aaagccttgt tagcgttgta gcgtaggaag gtcatcactt cctcggtcca gccaacctca
     3181 tcatagaggg tcttggtgta ttgctcttca ttttcatata gctgatacag caggtcatac
     3241 atccagtcac gaaggctttc ttgctcactc tctgatagct cattaaagcc cagctgaaac
     3301 ttgtagccga tataagtgcc atgaacggac tcatcacgaa tgatgagctt aataatttca
     3361 gcgacattag ccagcttatt gttgcccaga taatagagtg gtgtaaaaaa gccagaataa
     3421 aatagaaagg tttcgagata agtcgaggct accttttttt gaagggcact gccattttca
     3481 taaatgtcgt tgattatctt agccttattt tgaagaaata cgttgttgtt ggtccactca
     3541 aaaatgtctt caatttcttt tttggtgttt agggtcgaaa agattgatga gtaggattta
     3601 gcatggacag actccataaa ttggatattg ttaagaactg cctcttcatg cggggtgcgc
     3661 acgtccttgc gaatggcttc gactcctgac tcagactgca tcgtatcaag aagggttagc
     3721 ccgccaaaga ccttacctac taaatccttt tcaacagcag ataatctgcg ccagtcatca
     3781 aggtcatttg atagtggaat acgtgtatca agccagaatt gctccgtcag cttttcccag
     3841 gttgacttgt caatgacatc ttcgatttca ttccagttga ttgcttcata gtatgtggtc
     3901 atgagtttct ccggtagatt gtaatatagg gttaggtatg ctaggaggag agccttgagt
     3961 gctggtctat cattaggaca ggtgcactga cacatcagct aggctctgac attaaggact
     4021 ggtccacctc actgccattc acttggttag atgacacagc tttcacactg attggctccg
     4081 acctcctcgc catcatcggt aaaggtgcgg atataataga ttgattttat ccctttatta
     4141 aaggcgtaat gtctcaaaat agataggtca cgagtggttt gcttgctttc tgttttccat
     4201 tcgtagagct cctttggcaa ttcgctgcgc aaaaagagtg ttaacgacag tccctgatca
     4261 acatgctttg tagcagctgc atagacatca atcacctttc tcatgtccat atcataggca
     4321 gatgtgtagt aaggaatggt gtctgtagat aggccgttgg ctgggtaata aatcttgccg
     4381 attttctttt cctgacgttc ttcgatccgc tgagtaatcg ggtgaataga agcagagcag
     4441 tcgttgatat aggaaattga tccattagga gcaactgcca gacggttttg gtgataaagg
     4501 ccatctgtca taatcgcttg acgcagcgcc ttccagtctg ctgcttgcgg aataaagtga
     4561 tccttgaaaa ggcttttaac cagctctgat tttggcacac attctcctgt gatgtactgg
     4621 tcaaaataag caccgctagc atatgttgat ttttcaaagc caacaaaggt tgtctgacgc
     4681 tcgcgagcga tctgattgga ttcgacaagc gtccagtaat tcatcagcat aaagtaaata
     4741 tcagtaaatt cgatagattc tgggctgcca tattcgatat ggtgctgagc caaataggaa
     4801 tgaagcccca tagccccaag gccaaaggta tgtgcttgac tgttaccatt tttaacagtt
     4861 gggactgctt cgatattaga ggagtcagtg acaaaggtca gggcacgtgt catggctctg
     4921 atggaacgac caaagtcagg tgacgtcatc atgtttaaga tattagttga tcccagattg
     4981 caggaaatat cagttcccat tttgacaaac tcctgcgcat cattaatgag actaggcgtt
     5041 tgaacctgta gaatttctga gcataggttg ctcatgatga ttttaccgtc aatagggttt
     5101 gacctgttgg cagtgtcgat gttgataaca tagggatagc cagattcctg ctggagcttg
     5161 gaaatctctg tctccaaatc acgtgctttg atttttgttt tggtgatatt aggattggca
     5221 accaattcgt catacatgct agtaatatca atgtagttaa atggcaggcc gtattctctt
     5281 tcaacactat aagggctaaa gagatacatg tcagcattgt gacgagcaag ctcataaaac
     5341 ttatctggta cagtaatacc aagtgacaat gtcttgaccc gcaccttttc atctgcattt
     5401 tcttttttgg tagacaaaaa agcgataata tcagggtgaa agacgcttaa atacaccaca
     5461 ccagcccctt gacgctgccc tagctggttg gaataagaaa agctgtcctc aaatagcttc
     5521 attacaggca caacaccaga agcagctccg gcatagccct tgattggagc gccagcctca
     5581 cgaaggttgg ataggctaat gccaacacca cccccaatac gggataattg caaggcagaa
     5641 ttaatagagc ggccaatggc attcatatca tctgtcacct gaaggagaaa gcaagaaacc
     5701 agctcaccac gacggctccg tccagcattt aaaaaagaag gagtagcagg ttggtaacgc
     5761 tgattaatca tctcaatggc taagtcctta gctaatgttt catcaccatc agcaaaataa
     5821 agggcattga acatgacccg atcctctatg ctctctaagt agaaattgcc atcattggtt
     5881 tttagggcat actgctgata aaatttatag gccgccataa atgatttaaa gcgaaagccc
     5941 tctgcttgaa tgctcttggc tagatggctg ataaattcag gagaatagtt ttggataaag
     6001 gctgattcaa tatagtcatt gtctacaaga taggcaatct tttcgttgat agaagaaaat
     6061 gacatggtgt taggaataac attttcggta aaaaaagcct ccaaagcttc cttgtcttta
     6121 tgaagtggaa tgctgccatc aacaggacgg ttaatttcat tgttgaggcg aaagtaagaa
     6181 atatcgccaa gatctttgag actcatatca attgttcctt gtctagttaa ataatatctt
     6241 ttaattttgc tggctgaaac cctgagaata ctatctgctc tgtctcaata acaggagcag
     6301 cagtaaagcc aaggctctta acatagtcca ctttttctgg atgctcatca atattaatct
     6361 cttggaaagc agctccatgc tgttctaaaa atttcttagt cattttgcac tgcatgcaat
     6421 tgtgctttga gtatactgta atcattgctc gtccttccaa ctattagtct ttcactcaat
     6481 tttaggaaaa atcaaatgac tctaatagga tataaaaaat gttcctaaaa agcaaacgat
     6541 ttatttcaga atagcacaag atattgtggt tgtgtgtgag aatatttcta aatattgtgt
     6601 tatcctctct tatcactgat aattgctaca agaggcttgt agttcttaaa tgcatactaa
     6661 tcaggttgga aggcttattt gacattatga aaatcatcat gtaagaaata ttgacaacaa
     6721 atgaaaatac aagaaaactg tttcatgatt ttttcttgtt agaacattta accttgaaaa
     6781 taaaaaagca ttgtgctata atcacctatt gtaagggtta tcatgtgata gctcgaaaat
     6841 acacaattca aaaggagaac catattatgg cttcaaaaga ctttcacatt gttgcagaaa
     6901 caggtattca tgcacgccca gctaccttac ttattcaaac agcaagcaaa tttgcttcag
     6961 atattacact tgactacaaa ggtaaagcag taaatcttaa atcaatcatg ggtgttatga
     7021 gccttggtgt tggtcaaggt gctgacgtaa caatcacagc agaaggcgct gatgcagatg
     7081 acgctattgc ggcaatcgaa gaaactatga ctaaagaagg attggcataa gactatgaca
     7141 gaaatgctta aaggaatcgc agcctctgac ggtgttgctg ttgccaaagc atatctgcta
     7201 gttcagccgg atttgtcatt tgagactatc acagtcgagg atacaaatgc agaagaagct
     7261 cgccttgatg ttgcactaca agcttcacaa gacgagcttt ctgttatccg agaaaaagca
     7321 gtagaaagcc taggcgaaga agcggcagca gtttttgatg cccatttaat ggttcttgct
     7381 gatccagaga tgatcagcca aattaaagag actattcgtg cgaagcaaac gaatgctgaa
     7441 acaggtctaa aagaagtgac tgacatgttc atcacaatct ttgaaggcat ggaagacaat
     7501 ccttatatgc aagagcgtgc ggctgatatt cgagatgtcg ctaagcgcgt cttggctcat
     7561 ttattaggtg ttaagcttcc aaatccagct acaattgatg aagaagcaat tgttattgca
     7621 catgatttga ctccttcaga tactgcacag cttaacaaac aatttgtaaa agcatttgta
     7681 acgaacattg gcggacgtac gagtcattcg gctatcatgg cccgtacact tgagattgcg
     7741 gctgtgcttg gtacaaatga tattactaag cgtgtcaaag atggtgacct tattgctgtt
     7801 aatggtatca ctggtgaggt tattattgac ccaagtgagg agcagattct tgctttcaag
     7861 gaagctggag aggcttatgc gaagcaaaag gctgagtggg ctctgcttaa ggacgcacaa
     7921 actgtcacag cagatggcaa gtactttgaa ttagcagcaa acatcggtac acctaaggac
     7981 gttgaaggtg tcaacgataa tggtgctgag gcggtaggtc tttaccgtac tgagtttctt
     8041 tatatggatt ctcaggattt cccaaccgaa gatgagcaat atgaagccta caaggctgtt
     8101 cttgaaggaa tgaacggcaa gcctgttgtt gttcgtacaa tggatatcgg tggggacaag
     8161 gagcttcctt actttgattt accaaaggaa atgaacccat tccttggttt tcgtgcctta
     8221 cgcatttcaa tctctgaaac aggtaatgct atgttccgca cacaaattcg tgctttgctg
     8281 cgtgcttctg tgcatggtca attgcgtatc atgttcccga tggttgccct tctaaaggaa
     8341 tttcgtgctg ctaaagtcgt atttgaagaa gaaaaggcta gcttgctgtc tgagggtgtt
     8401 gcggttgcag acgatattca ggttggtatc atgattgaga tcccagcagc agcaatgctt
     8461 gctgaccaat ttgccaagga ggttgacttc ttctcaattg gtacaaatga ccttatccag
     8521 tacacaatgg cagcagaccg catgaacgag caagtgtcat acctttacca gccatataac
     8581 ccatcaatcc ttcgtttgat taacaatgtt atcaaagcag ctcatgctga aggtaagtgg
     8641 gctggtatgt gtggtgaaat ggcaggtgac caacaggctg tgccgcttct tgttggtatg
     8701 gggcttgatg aattttcaat gtcagcaaca tctgtgcttc gcacacgtag cctgatgaaa
     8761 aagcttgatt cagcgaaaat ggcagagtat gctcatcgtg cactcacaga atgctcaact
     8821 gctgaagagg ttcttgagct tgccaaagag tatattacag aagcttaaat agaaataacg
     8881 aggagctggt tttgtccggc tcttttttac tagaaaaatg actaatcaga tccatatgaa
     8941 agcttgcttt ataaagtagt ttgatgtttc aagttttatc agaattttca gactcttcct
     9001 gtagcgaatt gttgaaatat gctaaaaaag tgatagaata atagtaccat tataaaagga
     9061 gaaaaaagtt tggctaaaca atataaaaat ttagtgaatg gtgagtggaa gctctctgaa
     9121 aatgagatca agatctatgc accagcaacc ggcgaggagt taggtagtgt accagctatg
     9181 tctcgtgaag aggttgatca ggtttatgcg tcagctcgcg ctgctcttgc agattggaga
     9241 gcgctttctt atgttgagcg tactgcttat ttgcacaagg ctgctgatat tttggtgcgt
     9301 gatgctgaga agattggtgc tgttctctca aaagaggttg caaagggtta taaggctgct
     9361 gttagtgagg ttattcgtac agcagaaatt attaactatg cagcagaaga aggccttcgt
     9421 atggaaggcg aggtccttga gggtggcagc tttgaggctg ctagtaagaa aaagattgcg
     9481 atcgtacgtc gtgagccagt gggacttgtg cttgcgattt cacccttcaa ttatccgatt
     9541 aacctagcag gctcaaagat tgctccagcc cttattgcag gaaatgtcgt ggttcttaag
     9601 ccgccgacac aaggctctat ttctggcttg ctcttagcag aggtatttgc agaagcaggt
     9661 cttcctgctg gagtctttaa taccatcact ggacgcggct cagttattgg tgattacatc
     9721 gttgagcatg aggctgtaaa ctttatcaac tttactggct caacgccaat tggagagcga
     9781 attggtaaat tagccggcat gcgtccgatt atgcttgagc ttggtggtaa ggattcagcg
     9841 attgtcttag aagatgctga tattgcctta gctgctaaaa acattgttgc aggtgccttt
     9901 ggctactcag gtcaacgctg tacagcagtt aagcgtgtgc ttgttatgga aagcgttgca
     9961 gaccagctgg tagcagagat taagggctta gttgagaaat tacttatcgg tatgccagag
    10021 gacaatgctg acatcacacc attgattgat accaaagcgg cagattttgt tgaaggtctg
    10081 gttaatgatg cagcagacaa gggagcacag gcgcttactg aaatcaagcg tgacggtaat
    10141 ttaatttgtc ctatcttgtt tgatagagta acaactgata tgcgcttggc ttgggaggag
    10201 ccatttggtc cggtgctgcc agtgattcgt gtaagctctg tagaagaggc aatcagcatt
    10261 tcaaatcaat ctgaatacgg tttgcaagcg tctatcttta cgactaattt tccacaggcc
    10321 tttgctattg ctgagaagct tgaggttggt acagtacaca ttaacaacaa aacccaacgt
    10381 ggtacagata atttcccatt cctaggggct aagaaatcag gagctggtgt tcaaggggtc
    10441 aaatattcaa ttgaggcaat gacaagtctc aaatcagtcg tatttgatat tcaataacaa
    10501 aaaagctagg gtatcttagt ttgaaagcag ttgcacattt gtgcggctgt tttatttgtg
    10561 tctctagttt taacagctag ctatgcaaga aggtgagttg tcccaacctc aaagatgaga
    10621 tctaaatatt taatgatttt ggggtcgtaa aaaagtttag agtgttttga tctccttaag
    10681 atgtgagtgt acaaagtctc gccaacagcc agcaggacta gccattgagg tcaaggaagc
    10741 tgctaaaata gctgatggtt caaaagcttg gtgaaaggct taatatctat cattgctatt
    10801 ttgagggctt tccattataa tatgaatact agagctactt gtcggtctgc ctcttgagct
    10861 gtgagatagc tgttggattt agttgtctcc ttgtccacaa aaggcttaga ggcaaaggct
    10921 gtggctatgc ttcttgcttc ttttagtgaa gtgtatgaga tcttatgaaa actcatatag
    10981 gctttggtat ctttgcaaga ggactaatgg cttgctttac ttgccttgat agagggctgg
    11041 gattgagggg tgatgacctg cggtggtcat ctctagagct ccttgcttct ttttttatgt
    11101 agactaatgg tttagactgc tagcttcctt gtttagaaag taggacatca tgttacccaa
    11161 gagaaaatta attgatcaac gtcttgatta tgccattatt tttcctgttt tttgtttgct
    11221 aatatttggt ctggtatctg tatatgtggc agcaagtcat gattttccgc aaagcctcgc
    11281 cactgttatg cttcaacagg ttctctggat ccttcttgga gctgtgattg cctttaccct
    11341 aatgtttttt agcacagaga ttctgtggaa attaacacct gtcttttatc ttttgggtgt
    11401 gctattaatg gttctgccac tcatcttttt tagccctcgg ctggtagctg ctacaggggc
    11461 gaaaaattgg attacgattg gctcaacgac cttgtttcaa ccatcagaat ttatgaaaat
    11521 atcctacatt ctggcaatgt cttggttaac ggtctggttt aagagaaagc aggagagaag
    11581 tcggttttta gatgattgga agctcttggg cttatacctt gtcttgacgt tgccggtcat
    11641 ggtcctgcta gcactgcaaa aggacttagg aacagctatg gtttttttag ccatcttagc
    11701 tgggattatc ttaatttcag gaatttcttg gtggcttatt ttaccagctt tggtactagt
    11761 ctttttactg gtttcagctt ttttctttgt ttttttgttg ccagagggaa aagaattcct
    11821 tttaaaaatg ggaatggata cctaccaatt gaatcgtatt tcagcttggc tgacaccgtt
    11881 tgatttctca gataccattg cctatcagca gacgcaaagt atgatttcga ttgggagtgg
    11941 tggctttttt ggtaagggct ttaatcagct tgagctgtca gtaccagtca gagaaagtga
    12001 tatgattttt acagtgatcg ctgaaaattt tggctttctt ggtgcagcta gcttactgat
    12061 cttgtattta atactgattt accgcatgct tagggtgacc tttgcatcga ataacctttt
    12121 ttatacctac atttcaaccg gctttatcat gatgatacta tttcatattt ttgaaaacat
    12181 tggcgcagca gttggtctgc tacctttgac cggtattccc cttcccttta tttctcaggg
    12241 cggctcttcc ttgatttcaa atctgattgg ggtcggcctg atcctatcaa tgaactatca
    12301 gcacgtcctt gctcatgaaa agcaaagcga gcatgagctt agcagaagct cacgttatgt
    12361 ttaagaggca tgtttggtcc ttgttcggtt agaatgagct gccaatcagc ccttttttat
    12421 ttgcttaatc gctataaaaa taaagaaaaa tatgttataa ttaaggttat gaattatcat
    12481 gattatattt gggatttggg cggcactctc ttggataact atgaaatttc tacccaggct
    12541 tttattgaga cgctgcattt ttttaagctg tctgcaagcc acgatgccgt ttatcaaagg
    12601 cttaagaaat caacagcaac cgccattcaa gtatttgctc ccaacgaacc gcaattttta
    12661 caatattaca aagcgaatga ggctaagaaa ttagccaatc ctatttggtg cctaggtgca
    12721 aaggacattc taaagaggat tgtggcatca ggctcgcgta attttttaat atcccatcgt
    12781 gatcatcagg tcaatgattt gctggagcag gctgggcttt tgggctattt taccgaggtt
    12841 gttaccgcct caaatggctt tgccagaaag cctaaccctg agagcttact ttatttgaag
    12901 gaaaagtacc tgatcagcaa gggcttagtg attggtgatc gcagacttga tatagaagca
    12961 ggacaagcag caggctttga caccctgctt gttgatggta gaaaaaacct attggagata
    13021 gtagattaga tggttgaaga aaataaacaa ttagaagaca aggctcaaga gtatgacgct
    13081 agccagattc aggtcttaga ggggttagaa gccgttcgca tgcgtcctgg aatgtatatt
    13141 ggctcaactg ccaaggaagg cttacatcac ctagtttggg agattgttga taattctatc
    13201 gatgaagcct tggcaggctt tgccagtcat attcaggttt ttattgaggc agataattcg
    13261 attaccgtta ttgatgatgg acgtggtatc ccagttgata ttcaagctaa gacaggccgg
    13321 cctgctgtag agacagtttt tacagttttg catgccggtg gaaaatttgg cggtggtggc
    13381 tacaaggttt ctggaggact tcatggtgtt ggctcctcgg ttgttaatgc cttatccaca
    13441 cagcttgatg ttcgtgtcta taaaaatggg catatccact atcaggagtt taggcgtggt
    13501 gctgtagttg atgatttggc tatcattgga acgactgatg ttacgggaac aacagtgcat
    13561 ttcacacctg atccagagat ctttacagaa acaacagaat ttgactacca ggtcctggca
    13621 aagcgtattc aagagctggc ctttcttaat cgtggcttaa aaatctcaat tacagataaa
    13681 cgagctggtc ttgaaagaga agagcatttc cattacgagg gtggtattgg ctcttatgtt
    13741 gcctttttaa atgacaaaaa ggacgtcatc ttcgatactc cgatttattc tgatggtgag
    13801 ctggagggga taacagttga ggtggcgatg cagtacacta caggttacca tgagactgtt
    13861 atgagctttg ccaacaatat tcacacacat gagggtggta cccatgagca gggctttaga
    13921 acagctctga cgcgcgtgat taatgactat gctaagaagg ctaagattct caaggaaaac
    13981 gaggataatc tgacaggtga ggacgtccgc gagggcttga ctgctgttat ttctgtcaag
    14041 cacccaaatc cacaatttga agggcaaaca aagacaaagt taggaaattc tgaggttgtt
    14101 aagattacca atcgcttgtt tagcgaagct cttcagcgct ttctactaga gaatccgcag
    14161 gttgcccgta agattgttga aaaggggatt ctagcctcta aggctcgcat tgctgccaag
    14221 agagcgcgtg aagtaacccg caaaaaatca ggcctagaga tttccaattt gccagggaag
    14281 ctggctgact gctcctcaaa tgatgctagt caaaatgagc tttttatcgt ggagggggat
    14341 tcggctggtg gatcagcgaa gtcaggtcgc aatcgtgagt ttcaggctat tctgcctatt
    14401 cgtggtaaaa ttttaaacgt tgaaaaagca acgatggata aaatccttgc taacgaagaa
    14461 atcagaagcc tctttactgc tatggggaca ggctttggag cggagtttga tgtttctaga
    14521 gctcgctatc aaaagctggt catcatgact gatgcagatg tcgatggagc tcatatcaga
    14581 acgcttttgt taacgttgat ttatcgcttc atgcgaccag tattagaggc tggctatgtt
    14641 tacattgctc agccaccgat ttatggtgtt aaggttggca gcgagattaa ggaatacatt
    14701 caaccgggag tcaaccaaga agaggagcta aaggctgctc ttgaaagaca tagcacagga
    14761 cgctcaaggc cgactattca acgctataag ggcctaggag agatggacga tcaccagctt
    14821 tgggaaacaa caatggaccc tgataatcgt ctaatggcac gtgtgaccgt agatgatgcg
    14881 gcagaggctg atcggatttt tgacatgctg atgggcgatc gtgttgagcc aaggcgtgaa
    14941 tttattgagg aaaatgcggt ctatagtacg cttgacattt agtcaaatat attttgaaaa
    15001 gcacctaaaa gtatgttata atcgtaacgt tatagtgtat ttttgataat ataataaaag
    15061 gcgattcttg ctagttgttc ctactgaacc ggcagttgat caatcgcatc taaataataa
    15121 ggagattaag atgtcaagcg gaattatctt gctgattgtg gccatagtct tactagtgat
    15181 tattgcttat ttagtgggtg ttattatacg caagcgtaat gacacattaa ttaccagtct
    15241 agaagaacga aaacaagctt tatttggcct tcctgttaat gacgaaatcg aggaagtcaa
    15301 gtctcttcac ttgattggtc aaagccagac ctcatttcgt gaatggaatc aaaagtgggt
    15361 tgatttgacc ctaaatacct ttaccgatat tgaaaagcat atctttgagg ctgagcactt
    15421 aaatgacacc tttaatttca ttcgtgccaa gcatgagatt aatagcgttg agagtcaatt
    15481 gaatctcgtt gaagaggata ttaccgctat tcgtgaagca cttggcatat taaaggagca
    15541 ggaagaaaaa aacagcgcgc gtgttactca tgcactagat ttgtacgaaa agttgcaggc
    15601 ttccgttgct gaaaatgaag ataatttcgg atcaacaatg gccgaaattg aaaagcaaat
    15661 gaagaatatt gaagcagagt tttcacaatt tgttgccctt aattcatcag gtgaccctgt
    15721 tgaagcagcg gaggttttgg ataaggctga ggagcatacg attgccttgg ggcaaattac
    15781 agagcagatc cctgctattg tagcaaagct tgaagatgat tttccggatc aattggacga
    15841 tctggagaca ggctatcgtc gtttgctgga ggaaaattat cacttcccag aaaaaaatat
    15901 tgaagcccgc tttcaagaga ttcgtgagtc tattcgtgcc aattcatcag agctggttac
    15961 ccttgatttg gaccgagcta gagatgaaaa tactcacatt caagagcgta tcgactcact
    16021 gtatgagctc tttgagcgtg agattgcagc ctacaaggtg gttgctaaaa atagcaaaat
    16081 attaccaaga tacctggctc acgccaagca caacaacgag cagttgaagc atgagattgc
    16141 tcgtctatca cgtaagtata tcttgagtga aaatgaaggc ttaaatatca aggcctttga
    16201 caaagacctc aaagatatcg aagacaatgt ccttgagatt gctgaagcct ttgatcagca
    16261 ggaaaagcca ttttcagagc tacagctgat tcttgatcgt agtatcaaga cgttggcttc
    16321 tgtagagtct ggtcagatgg acgtctttgc tgctgttaaa gacattgaaa agattgagtc
    16381 acaggctcgc cagcacttag aaatctacgt cacacagctt cacatgatta agcgttatat
    16441 ggaaaagcgc aatttaccgg gaattccaca ggattttctg agtaccttct ttaccactag
    16501 ttcgcagcta gaagcattga tggacgaact aagtagagga cgtatcaaca ttgaagcggt
    16561 gtcccgtctg tctgaggtgg caacagctgc tattgctaat ctagaagagc taacctacca
    16621 agtggttcag catgctacct tgacagagca gctgctccag tactctaacc gttatcgttc
    16681 ctttgaagct ggcgtgcaaa atagctttga gcatgccttg aaattgttcg aggtggacaa
    16741 tgactatcag gcatcatttg atgagatttc ctatgccttg gagacagtcg agccaggagt
    16801 gacagagcgt tttgtcaatt cctatgagaa gacacgtgaa cgtatccgct tctaatgtga
    16861 caagggttga tactttatat tacgaaaaag cttgaaaaag cagtccatgc tgggctatgc
    16921 tttttcaagc tttttgaatg gtcaggctat ggcctccttg agctataccc aaaaagctgg
    16981 ttcaagccag tcagtagaga tagacaaggc cttagtgcta ttgggctgtt gctacatgag
    17041 atattttgta ataaaatcag acgattatcc atttaattaa aaaaaaaaaa aaaacgaaac
    17101 tgcggaggaa acctgacgag taactattta tggctatcaa tcagcatgtt acactctttt
    17161 tggaaggcct agcaatcact gactgtgagg ttaaccaaag aaaataagat gttaaggaga
    17221 atatcaatga aaataactaa agcattgtgt gtagcaggtg ctgttgcagt cctagccttg
    17281 gcaccaatca gctcaagtcc tgcaccaaca cagactgtat ttgctgctac acgtggtact
    17341 gaagagtact gtcataatgg gtggtgcagt tttcttgatg aacatggtga gtggaacacg
    17401 aaacgtgagg gcgaatctaa tagtccccta cagcgaggtt catggtggga ttggatttct
    17461 tattggtctg gttatatatg gtattctgta tataactggt ttaggtaacc tctcaacgcc
    17521 actgctacca tactgataaa tcccttagac tattctaagg gatttttact gcaaaaagca
    17581 catagggaca aggcaataca agctccagcc tgttcttagc tccctatacc ggtaaggatc
    17641 ataacactca gaactccggc agatgattgc aggagctatt ggagagtgag gactagtgaa
    17701 agagcctctg ccagagggat ttgcccttag tctttgtttg ttcagcaggc ttattgtcag
    17761 agggcttgtc tagtatagcc ttgagattgg tttcctcttt ggtgatggca tgatcactat
    17821 gaatgatcag agcaaaagga gagacagctc ctttctcatc tacaatagtg gcagatagag
    17881 cgttttgttg ggccaatttc atatagtaca tttgataagc agagccgaat tcagaggata
    17941 atttgaatga caaggggaaa taagcctctt tgaggtgagg cagctgggct gtgatgtagc
    18001 ctttagcctt ttcatgatca acctctgtca agggaagcgc taagacaatc ctttcagcat
    18061 aggtccctaa ataatagcgt tgttggtcgg ggtcaaatcg gttttctcct gaagctccct
    18121 ttaagagtct tgtatctaat gaatccatac aatcctttca agcatgtgat actgtcatta
    18181 tactattaac tgcgccaaat accaatgata aagcatttac taggtatttg atcggctttt
    18241 ggaagaagat gaaatcaaag aaaaacagca tgaaaacaac tctcttattt catgaaatta
    18301 gtttttaagt tgcttaagac cctagtttgt ggtattatta acatgtaaaa tattaaaact
    18361 cataaggaga gtattataat gtcaattatt actgatgttt acgctcgcga agtccttgac
    18421 tcacgcggta acccaacact tgaagtggaa gtttatactg aatcaggtgc tttcggacgt
    18481 ggtatggttc cttcaggagc ttctactggt gagcatgaag cagtagaact tcgtgatggc
    18541 gacaaatctc gttaccttgg tcttggtact caaaaggcag ttgacaacgt taacaacatt
    18601 atcgctgaag cgatcattgg ttatgatgtt cgcgatcaac aagctattga cagagccatg
    18661 atcgctcttg acggtactcc aaacaaaggt aagcttggtg ctaatgctat tcttggtgtg
    18721 tctatcgctg tagcgcgtgc tgctgctgac taccttgagg tgccacttta cacttacctt
    18781 ggaggattca atactaaggt tcttccaact cctatgatga atattatcaa cggtggttct
    18841 cactcagacg ctccaattgc tttccaagag ttcatgatta tgccagttgg tgcacctacc
    18901 ttcaaagaag gtcttcgttg gggtgctgag gtattccatg ctcttaagaa aatccttaaa
    18961 gcgcgtggac ttgttactgc tgttggtgac gaaggtggat ttgctcctaa atttgaagga
    19021 actgaagatg gtgtagaaac aatccttaag gctatcgaag ctgctggcta tgaagctggt
    19081 gaaaatggta tcatgattgg ttttgactgt gcgtcatcag aattctacga taaagagcgc
    19141 aaagtctacg actacactaa gtttgaaggt gaaggcgctg ctgttcgtac atctgcagag
    19201 caaattgact accttgaaga attggttaac aaatacccaa ttatcacaat cgaagacggt
    19261 atggacgaaa atgactggga aggctggaaa gcacttactg agcgcctagg caaacgtgtt
    19321 caattggttg gtgatgactt cttcgttaca aacactgaat accttgctcg tggtatcaaa
    19381 gaaggtgcag ctaactcaat ccttatcaag gttaaccaaa tcggtacttt gactgaaacc
    19441 tttgaagcta tcgaaatggc taaggaagct ggctacactg ctgttgtatc acaccgctca
    19501 ggtgaaactg aagattcaac aatcgctgac atcgcagtgg caacaaacgc tggccaaatc
    19561 aaaacaggtt cattgtcacg tactgaccgt atcgctaaat acaaccaatt gcttcgcatc
    19621 gaagatcaac ttggtgaagt tgcacaatac aaagggatca aatcattcta caaccttaaa
    19681 aaataatttg attttagatt aaaaggttga caagccttga ttttaaagca ttctaggact
    19741 gtcctagagt gcttttagtt ttagcttcat gtcaactgta gtgggtgact gatagctaag
    19801 cacgagagga gacgaaggtc gccttctctt tttcaatcgg ataaggctag ggaatcccca
    19861 aatgtcgatg aagggaattt tagaaggttt ctggaagtcg tatatgattt gtttcccttt
    19921 gcagtgtcta cacctaggag actgatagtc cagtgtagcg ctgacttcga tatgagtatc
    19981 gtgctggata gtcttattca aggtgatatt ttgatctttg attccgatga gtagtgtggt
    20041 atgatgaatc tgttccataa gacactttct aatgatggtc tggtcgcttt tcatgataag
    20101 ccttatggaa ctttttgggt actcaaaaag ccctataatc ttcataatga atttacccat
    20161 tacagaaatt atagagccaa tatttagagg attttagcct attggtagat tgacagtttc
    20221 ttaagattgt gttacaatgt aacacaaaga aacgaggtaa acgactatga gtacagttac
    20281 tatcagatta aatcaagaag aagaaatatt tttcaaaagt tacgcccaac tcacagggca
    20341 aagtttatca agtctattta aaaaagccct tgagcgggat attgaagatg agtatgattt
    20401 aaaaatctat catcaagcct atgctgaata taaagcagac cctgagacaa ttagccatgc
    20461 tgattttaag aaagagctag gcttataaca tgtaccgtat agagtattct aaaaaggctc
    20521 aaaagcagat taagaaagta gataagcaaa ttcagaggtt gctatttgct tggattgata
    20581 agtatttaga gggaacagat aacccacgcg caaatggcaa aggtttgacc ggaaatcatg
    20641 ctaatgagtg gcgttatcgt attggtgatt ataggcttat ttgtgatatt caagatgata
    20701 agatggttgt tttagcgctt gagtttgggc atcgtaaaga tatttactaa cgttgaggaa
    20761 gtaagatggt caaaaataat gcaattggta gcaactggaa agatgtaaga gctgagttat
    20821 tcagcaagga agaattttag aaagtgatgc tcgtattgct attatggaca agtatagtta
    20881 aaaagtgtgc gtttttaatc tgtatgatga agtaattgat aaagtaacag gtcaaaaggc
    20941 tatcattgtc tgtattgcta ataaattggt agatgattgt tatttaatcg aaccgctaaa
    21001 ccattcttac ttaccagatt ggcgtgagat aaatcagtta attcgatata aaaattagca
    21061 ccttatcggg tgctaattcc ttgcctgctg aactcataat ttaatacctt ttttactacc
    21121 ccatatgttt cccctaatta tgtgtacttg ctagatataa ggttaattgg gatagaattt
    21181 tgaataaagt tgttgtattt tgtaatagtg attgatattg ggataacctt aaaaaaataa
    21241 tttgatttta gattaaaagg tttacaagct ttgattttaa agcattctag gactgtccta
    21301 gaatgctttt agttttgata agcacaatcc gctgttgact gtataaaccg tatatgatac
    21361 aaaataagag cttgtagcag tgaagccact aactctagtg ctgtgggctc aaccttgatt
    21421 gatgaatccc ttgcttttaa tgcgtttatg aagcagtggc gtatcagtct agctcgttgt
    21481 ggaaagcaat taactagaga agaattacta tcctcaatca atatgctgac agccgcaggg
    21541 atttgtgagt ttgatttgct gtggcagcgt cttgctccta aggggtgtca gcgtcccaaa
    21601 tggagccatc agctggagag gctctttgcg gatacaaagc cttgtctaca ggtcttgtct
    21661 gagacttatc agcttgggat tattgctaat caggcaaagg gtctaaaaga gcgcttagag
    21721 aggtttggga ttagtcatta ttttgccctt atgatatctt cttctgatgt ggggctacaa
    21781 aagcctgatc ttgctctgtt tcgctatgca cttgatcaag caggcgtatt agcgcgtgat
    21841 gctgtttata ttggggatcg tgttgacaat gatattattc ctgctaaggc attgggaatg
    21901 agagctgtca ggattcatca agggcttgct gcgtccagtc cagatgatag gctttatcct
    21961 agtgatgtcc atattagcaa acttagtgac ctgttagaat gcttttaacc agtctttagc
    22021 ttgaactagc ttttctttgt ggtctttctg ggtgaatggc agcaagcttt ggagtcatgt
    22081 tatggctaga ccttggatct aagggcgctg agcgtctcat atgatgaggc cgatcaagta
    22141 gtctccttga caagtagatt attgtttggt gcttataggt ggctttaggt gatgactggt
    22201 tttgcctcaa ctaaggctcg ctattgctat ctggggtatc ttctgacttt tttaatgtgc
    22261 tcttatctgg ttggattaga cctgctcctt gcttgaggaa agctgttttt aacgctgatg
    22321 agtctgggaa atggtgagat tggtgttggc ttttactagt ttttttgcgt ttacttgggc
    22381 taactttata tgagaaaaaa agaaaaatat ttattttatc tgttattttt gttacaataa
    22441 gcgtgtaaac taagatgcat taaaaaggag tttttatgtc gaataagaaa ttttttactt
    22501 atgcttcatt attggcatta atcgctgttc ctactgtggt tgaagaggtg actgcacagc
    22561 cttcagctca gcttgtttat gcagatgagc taaggctatc accaagtacc gactcatctc
    22621 cagtaacaaa gaccgatgag gctgatcagc cagttgctca atctgtttct gcgacagaac
    22681 cagtagaggc tcttgttatt gcggataaag aaagcgcttt aaatcctgct gttctagctg
    22741 atgccgatgg aagtcagccg attgcagtgg ttagagctgg tcaagagggt cagccttata
    22801 ccgttactgg caaaatcatc agtgctgtta atggctgggg tggtcatggc ttttatatcc
    22861 aggacagtca gggatcaggt ctttacattt atccaggaag tgctttgggg tacgtgactg
    22921 gtgatgtggt gcagctgaca ggaacactga ctacttacaa gggtgagctt cagcttaaaa
    22981 cgattacaaa gcatcataag attaatggcg aattaccaac acctattgct gaggtaacca
    23041 ttccggagct agaaaaagca agcccgtcta ccctggtgaa gctttcaaat gtgactgttg
    23101 gagacatttc atcagataag cacgaaacct cctcttttaa ggtcagcgat acagctggca
    23161 atagtgttgc ggtgcgtctt gataatcgta caggtgttaa gacctctgac ttactctcta
    23221 aaattggcaa gggtgatgtg attaatctga cagctattca ctcaaccttt gatgggaagc
    23281 tccagctcaa gccctttagc cttgagcaat ttgaggtagt aaagaaggtt gttcgagaag
    23341 aagaggtgac tcctcttggt cgagtggtta aaatcggcca aattcaaggt gccagccaca
    23401 cctcaccgct cttgaatcaa gctgtaacag taaaagaggt ggtggtgacc tatcctgatg
    23461 atgcaactca tttctatgtg caagatatta atggtgacaa cgataaggcg acctcagacg
    23521 gtattcgtgt ctttgctcaa aatgctcagg tgcaggctgg tgatgtgctg accatttccg
    23581 gaacagtgga ggagttcttt ggcaaaggct acgatgaccg taagcagacg gatctgacca
    23641 ttacgcaaat caaggcatct aaggtcacta aaacagggac tgctcaggta ccagctccgc
    23701 ttgtgctagg taaggatcgt gttgctccag ctaatatcat tgataatgat ggctttagtg
    23761 tttttgatcc agaagaggac gctattgatt tttgggaatc cttggaggga atgcttgttg
    23821 ccgttgataa tgccaagatt ttagggccga tgtctcataa ggaaatttat gtgttaccag
    23881 ggtcatcaac tcgagtgctg actaactcag gtggtatttt acttcctgag acaggctata
    23941 atacagacct gattcctgtt ctctttaaaa aaggaaagca aaccatcaaa gctggtgatt
    24001 cctatcaggg acgacttgca ggtccggtat catatagcta tggtaattat aaggtgtttg
    24061 tcgatgacag cagtcgtatg ccagtcttgg ttgatggtca gctgaagcct gaaaagacac
    24121 acatcaagaa ggaccttagc aagctaagca ttgcctcata caacattgaa aacttctcag
    24181 caaacccatc atcaacaaaa gacgagaagg taaggcgcat tgcagaatcc ttcatctatg
    24241 acctaaatgc tcctgatatt attggtctca tcgaggttca ggacaataat ggacctactg
    24301 atgatggcac aacagatgca acacaaagcg ctcagcgctt gattgatgcc atcaaggcct
    24361 taggtggacc agcttatcaa tatgtggata ttgctccgga aaataacgct gatggtgggc
    24421 agccgggcag taatattcgg acaggcttcc tgtatcagcc aggacgtgtc agcctttctg
    24481 ataagcctag aggtggtgtt aatgatgcgg tgaaatgggt aaatggtgag ctaagcttga
    24541 gtgttggacg tattgaccca acaaatcctg cttggaatag tgttagaaaa tcattggctg
    24601 ctgagtttat tttccaaggc cacaaggttg tggtggttgc caatcatttg aattccaaac
    24661 gaggcgacaa ttcattatat ggacgtgttc agccggtaac ctttaaatca gaggaaagac
    24721 gtcatgtctt agcaaggctt ttgagccaat ttactaagga aggtgctagt cagcaggcta
    24781 atatcgttat gttgggtgac tttaacgatt atgagtttac gaagaccatt aagctgattg
    24841 aagaaggaga tatggcaaat ttggtgagca ggcatgagct ttctgaccgt tattcttact
    24901 tctatagagg aaataaccaa acgcttgata acatgcttgt ttcacgcaat ttgcttggtc
    24961 gctacgagtt tgacatggtt catgtgaatt caccatttat ggaagcgcat ggacgtgctt
    25021 ctgatcatga tccgttgctt cttcagctct cctttggaaa agacaagcca gcagcaccat
    25081 cagatcagcc aaagaaaaca ccagcaccag ctgcgacaac tcaagcctct aaggcaggac
    25141 gtgcacagct attgccaaaa acaggtgata agacagcgct tatggtaagt attttaggct
    25201 taacagctgt ctttagctcc tttagcctgt ttaggaaatg tcaggaaagg aagtaaagga
    25261 tttctttggg gtaggccagc agctgagcgg ctactgcgtt ttgtctgctg gtgctatata
    25321 ggtggttgaa gcgagcgaag agaggtatgc ttcctaggat catagcacaa tatcttatgc
    25381 ttataaacga acacaatgct ccttatgagc attcaaaacc tatactcaaa aggaatataa
    25441 cagctgagtt aagagggatt gcttttgaca gattgtggta aaaaaaggga tcttgaggaa
    25501 ttggctagtg atctagctgc caaaatgcga tgtcttgttt gactattttt ccctattggg
    25561 atataatgac aatagaaaaa gggtagttgt ttgcgcaact accctgtgca gaaccgttta
    25621 agacggtggc agaatgaaag ttaaaaaata atcgtcgacc taccaaagtt cagacggtta
    25681 ttttttattg tttaatatga cgattgcaac gactaagctg attaaggtaa gtaagaaact
    25741 accaaaagcc agcatgagtt gaagggcctc gtaagtagac aataaaacgc tcctttcagt
    25801 tggattttga tgcattgccc ataggcatca ccacctttca gaaatcagag ccaccgtctt
    25861 agcttttctg taaagaacat tatatcataa tcacatgaga aagccgttag attttaaact
    25921 gatcaggcgg ctttttggtg ttttgctgtc ttttagtgga atcgcctaag ctttgctgta
    25981 tagtatggga ttttatgctt tttgtaaggg cttaggctgc tatggcaggg tccatgtcct
    26041 ttgtcaatag cttagtttta tggtacaatg taggcgttgc ctagcaaccc ttggtgctta
    26101 gttccctttc accaagcata ttacaaacgt ggcggagctg tttatgctct agtctgacgt
    26161 caaaggagaa acacatgaca agttttactg ttcgtgacta tgtttacatt gctctagtgg
    26221 ctgcccttta tgtggttttg acaatcactc cacctttgaa tgctatttcc tatggcatgt
    26281 atcaatttcg ggttgccgag atgatgaatt ttttggcttt ttaccataaa aagtatatca
    26341 ttgcggtgac cttgggctgt atgattgcta atttttatag ctttggcttg attgatgttt
    26401 tggtgggtgg aggctcaacg ctcatttttg ttagcttagg tgtcgcttta tttaagcaat
    26461 accaagagga atatctctta aatggcttgc tgaataaggc ctttgtttat ttctcactat
    26521 tttttgcgac ttctatgatc accgttgcga ttgagcttta cttctttgga gcaccatttt
    26581 tcctaacttg gtttaccact gctgtagggg aatttgcttc acttatcatt ggctctatga
    26641 tcattgatcg cttatcaaaa cgcattaatt tacgacaata atagtaacat gtagccttcc
    26701 gtttttggga ggctttttat gattttcttc tagctaggca atagcttatt tgctatgttt
    26761 tgtgataaaa taagactatg aaaaaacgca taagagaatt gactgatctg ttaaatcaat
    26821 accgtcagga gtattacacc aatgacgctc cttctgtatc tgatagtgag tatgataagc
    26881 tttatcgtga gcttgtagag ctggagcaga cctatccagc ctatatccta aaggacagcc
    26941 ccacacagct ggtgggcagt acgattttga caggatttca gaaatatcag caccagtatc
    27001 cgctctttag tttgcaggat gctttttcac gtgaagagct taacgccttt gatcagcgga
    27061 tcaaatcagc ctttcctgag gctgaatacc ttgctgagct aaaaattgat ggcttgtcca
    27121 tttcgctggt ttatgaggct ggtgttctaa aggttggagc gacacgtggc gatgggacta
    27181 ttggcgagaa tatcactgaa aacattaaga atattaagga tattcccaaa cggctaagtc
    27241 aagcacttga tgtgacgata cggggggagg cctatatgtc gcgtcaggcc tttaagacga
    27301 tcaatgaaga gcgtcaggaa aatggtgagc cagaatttgc caatccaaga aatgcagcgg
    27361 caggaacctt gaggcagctg gatactagga ttgttgccaa gcgacagcta gcaacctttt
    27421 tgtatcagga ggtaggccta gaaactgctg atagccagca aaagaccttg gagcgcttgg
    27481 ccgatttagg cttttcggtc aatagccact atctgctgtc ctcatcgatg aatgacattt
    27541 gggactttat ccagagcatt gaagctagta gagaagagct accttatgag attgatggtg
    27601 tggtggtcaa ggttaatcag ttggcgatcc aagaggaact tggctttacc gtcaaggcac
    27661 cacgctgggc tattgcttat aagtttccag cagaagaaaa ggaagctgag attgtatctg
    27721 tggattggac ggttggccga acaggtgtgg tcacaccaac agctaatttg acccctgtgc
    27781 agctggcagg caccactgtc agtcgagcga ccttgcataa tgttgattat atcgcagaaa
    27841 aggatattcg cattggggat acggtggtgg tgtataaggc tggagatatt attccagctg
    27901 ttttgcgggt ggttgaggct aagcgtaggg atcaggctcc aatgcccatt cctacagcct
    27961 gtccttcctg ccagagtcag ctggtgcatt ttgaggacga ggtagctttg cgttgcatta
    28021 accccttgtg tccgagcttg gttcaacgga gcttggagca ttttgccagt cgtcaggcga
    28081 tgaatatcgc tggtcttggt ccagcggttg ttgaaaagct ttattctgct ggcctggtgc
    28141 atgatgtggc agatatttac cgactaagct tggaggattt gctgacgcta gatggtatca
    28201 aggaaaagtc ggctgaaaag ctcttggcag ctattgaaca atcaaaggca aactcagctg
    28261 aaaagctctt gtttggactt ggtattcgtc atattggcgc aaaggctagt cgtctgatat
    28321 tagaggctta cggtgattta gaggcgctgt tagctgtaac cgctgaagag ctcgctcaga
    28381 ttgacgggct tggtctagtg atcggacaat ccctggtgca gtattttcag caagagcaag
    28441 ccgctcagct gctagctgaa ttaaaatcag ctggggttaa tctggcttat ttaggccaaa
    28501 ggcctgatca acaggctgcg ctgtttggtt taacggtggt attgacagga aaattagaaa
    28561 agctaaaccg tacccaagcc atggaaaagc tagagcagct tggtgctaag gtaacaggaa
    28621 gcgtttctaa aaaaacagat ttagtggttg ctggcagcga ggcaggctct aagctggcta
    28681 aggcccagca gctgggtatc agaattgaag atgaggattg gttgctcaat ctttagtgag
    28741 gtaataacat gaaaaaacaa atgagggctc gtctgattta caatccaacc tctggtcaag
    28801 aaatcatgaa aaaaaacgtt gcagaggtgc tggatatttt ggaaggcttt ggctatgaaa
    28861 cctctgcctt tcaaacgaca gcagctaagc actcagcctt aaaggaagca agaagggcag
    28921 ctaaagcagg ctttgacctc ttgattgctg ctggtggaga tggtacgatc aacgaagtag
    28981 tcaatggcat tgctccccta gagaaaagac ctaagatggc gattattcca gcaggaacca
    29041 ccaatgattt tgctagggcc ttaaaggtac caagaggcaa tcccgttgag gccgctaagc
    29101 tgattggtaa aaatcaaacc atccgcatgg atataggacg tgctaaaaag gatacttatt
    29161 ttatcaacat ttcagccgca ggaagcctga cagagctgac ctatagtgtc cctagtcagc
    29221 tcaaaaccat gtttggctac ctggcttatc tggctaaggg agtggagctc ttgcctcgag
    29281 tgagtaatgt tccggtgaaa atcacgcatg atcatggcat ttttgaggga gaggtatcaa
    29341 tgatttttgc agccatcact aattctgttg gtggctttga aaagattgcc ccagatgcta
    29401 agctagatga tggcatgttt acccttattt tgattaaaac agccaacctg tttgaaattg
    29461 tgcacctgct gcggttgatc attgacggtg gtaagcatgt tacggatcgc cgcgtcgaat
    29521 acattaaaac cagtaaaatc accattgagc cccaatcaga taagcgcatg atgattaatt
    29581 tagatggtga atatggtggt gatgcgccaa ttaccctaga aaacttaaaa aatcacatca
    29641 ccttttttgc aaatactgat ttgatttcag atgatgccct tgtcctagac caagaggagc
    29701 tggaaatcga agaaatggtc aagaaatttg cgcatgaggt agaggattta gagcagggat
    29761 tggaggaata gggctagtta tggataatgc agttattgtt cattatcata gttgcaaggg
    29821 acattatttt caattaagtc tatggcaatg gcgagatggt aagctgggca aggacgctta
    29881 tttttcgagg tttgacagct ttggagcagt tgcttatctc acttatccag caccttattt
    29941 tttgagtcat gcttatgtga ttgtaaagga tcagttttgg cagcatcaaa ccgttgattt
    30001 tcggattgag cgtgattatg gggttccaaa gactgaggtg tggcttgttg atggtgatcc
    30061 tacggtttat tattcgagac aggctgctgt ggctagtcga catgatggta gatgtgatgt
    30121 gcatgccttt gatatggctg tcaatagtca ggcctttgac aagcgctggg gctttagtgg
    30181 ctggctaggc tttcgctatc agcctgagga gacgtctttt cgtttgtggg ctccaacagc
    30241 agaaaaggtt gagctcattc tctatgcttc gactgatgag agagctagtg ttgccaaggt
    30301 tttgcccatg cagcgtgggc agcagtactc gccagatcat catgcagaaa acacatgtgg
    30361 tgtgtgggac atcagcctaa gaggtgatta taattaccat gcttattgct accgggttta
    30421 ttatcgcagg cgtaccttta gagacactag ggatccttat gcgatcgcaa cgacagcaaa
    30481 tggcaaaagg tcaattgtca ttgcaccgga gcatttaaga ccgcagggct tttcagtgaa
    30541 gcagggtaag gaggctacct ggcgcttaga caatcctaat caggcggtga tctatgaaat
    30601 gcatgttcgc gacttttcaa aatcagaaac ctcgggcgtt agcttggcta atcgtggcaa
    30661 atttaagggg ctgattgaga caggcacgcg caatgctttt ggagattcaa cctgctttga
    30721 ttatgtcaag tcccttggca ttacgcatat tcagctccag ccggtctttg accatcatca
    30781 attctttgat gaaaatggag attatgccta taattggggc tatgaccctg aaaattacaa
    30841 tgttccagca gccagcttta ccagtaatcc gcatgagcca gctacccgta tcctggaatt
    30901 aaaggaggtc attcaggctt atcatgatgc aggcatcaat gtgatcatgg acgtggtgta
    30961 caatcatacc tactcatcaa gagagtcagc ctttcagctg acggttccgg attattatta
    31021 ccgtatgaat cctaatggct cctttcaaaa tggctctggc tgtggcaatg aaacggctag
    31081 tgaaaaggaa atgtatcgca aatacatgct tgattcgatc ctatattgga ccaatgagtt
    31141 taacattgat ggcttcaggt ttgatctgat gggcttacac gatattgaca ccatgaatct
    31201 tatccgacaa gagctagata agattgaccc aaggatactt gtttttggtg agggctggga
    31261 tatgggagtt ggtctggcag ctgagcagaa ggctaaaaaa ggaaatgcca gccaaatgcc
    31321 tggaatcggc tttattaatg atgatcagcg taatgcagtt aagggggcag aggtctatgg
    31381 gagcttagag aagggctttg tatcaggtgc accgacagaa ggacttgtag ccaagtctat
    31441 tttgggcagt gatgagctgg tctcttattg tacgcctagt caggtgatca attatgttga
    31501 agctcatgac aactataacc tcaatgattt gctgtgggtt ttgaatccag aggacagcaa
    31561 gcaggatcat gtcaaacggg ttcagctagc ttcagctatg acgattctca tgcaagggat
    31621 ttactttatg cagctgggtc aggaattttt acgaacaaag ctttacccaa caggtcagga
    31681 taaggagctg acacaggcag accgagaaag ggcgatgaat tcctacaatg cacctgacaa
    31741 tgtgaatcag gttgactgga gacaggttag cttggagcgc gaaacggttg ctattatgaa
    31801 aaaactaatc tatctgaaaa ctaaaacagc tttgttttca tacccatcat ttgagcaaat
    31861 cagacagcat gtttacattg agcatgctgg tgaaaatacg ggcttcatta gctttacagt
    31921 agaagatgaa agaaagtatc gattgatttt ctctagtttt agaaaccgct tgcaatcatc
    31981 tgctaatcat gttataattg aaacaaatga taagcgcttt caagatagtg agtccatgct
    32041 agatgagctg acagcgatga tccttgacat cacacaatag cctgagtgtt ctcaggttat
    32101 ttttgtttgt tgtcaaggat aaaagggctg tagttacagt tagcagagac ctattaggac
    32161 cttgcttatc atatcgctta gcgccttgaa aaagggttta ggagtaggga aagaagaggt
    32221 gatgggatgg ataatgactt agcgctttat acctttggca caggtgagaa ttttcacata
    32281 caggattatc taggtgttca tcggattaac aatgacacag gcaccagcta tgtctttagg
    32341 gtatgggcgc ccaatgcaga ggctgtcagc ttgattggag attttactga ttggcagtcc
    32401 aatccacttg agatgagccg aaatgaggct ggcgtgtggg aggttaccac tagcttgccg
    32461 caggaaggag atatttataa gtattgggtt aggcgccaag gtggtcagct tgttgaaaaa
    32521 attgatccag tggcctttct atttgaagct agaccaggaa cgggtgctat tgtcaaaacc
    32581 cttccagcca aaaaatggcg tgatagctta tggatgggac ggcgaaagcg ttttggcttt
    32641 aggcagcgtc cggttaatat ctatgaggtt catgcccatt catggaaaaa agacgaaaac
    32701 gcaaggccct atgactttag caagctaaaa gaagagctca ttccctatct caagagcatg
    32761 cactacactc atgttgagtt tatgccggtc atggctcacc ccttagatat gagctggggc
    32821 tatcagctga tgggctactt tgcctttgag tcaacctttg gaagcccaga agcctttcag
    32881 gattttgttg aggcctgtca tcttaataat attggtgttt tgattgattg ggtgccggga
    32941 cattttacac aaaatgatga cgccttagct tattttgacg gtacagctac ctatgaatat
    33001 caggatcacc atcgtgctca taattatggc tgggggccct aaattttgat ttgggtaaaa
    33061 ctcaggtaca gtcctttttg atttcaagtg cccttttttg gctggaggct tatcatgttg
    33121 acggcattcg agtagatgct gttagcaata tgctttactt ggattatgat caaggccctt
    33181 ggactccgaa tcaatacggt ggcaaccaaa accttgaggg gatagccttt cttcaaaaat
    33241 taaccacagt tatcaaggaa aaacaccctg atgtgatgat gattgcagag gaggcgacct
    33301 cagctacccc aataaccagc cctgttgcag aagggggact aggctttgat tataagtgga
    33361 atatgggctg gatgaatgat attcttaggt tttacgaaga ggatccttat taccgaaaat
    33421 acgatttcaa tctcttgacc tttagcttta tgtattgctt taaggagcat tacattttac
    33481 ccttttctca cgatgaggtt gttcatggca aaaaaagcct catgcataaa atgtgggggg
    33541 accgctacaa tcaatttgca ggcctaagaa atctttacac ctatcaaatc tgccacccag
    33601 gcaagaagct gctttttatg ggatctgagt ttggacagtt tttggaatgg aaatacgatc
    33661 atcaattaga gtggcaaaat ttagaggacg agctcaatgc caaaatgcag catttcacag
    33721 ccagcctaaa tcagctatat aaggaccata gcatgctgtg gcaaaatgat gaaacctatg
    33781 acggcattga tattattgat gcagacaata aggacgaatc agtcttgtcg ttttgtcgtc
    33841 aaaacaataa aggagagctc ctgctttgtg tctttaacat gacacctgtt gaaagaccag
    33901 gctttaccat aggtgtgccg atagcaggtc tttatcaaga aattttcaat acagagcttg
    33961 aggcctttgg aggtgtctgg aaggagcaca atcccttaac caacacagta gccaagaaat
    34021 ggaagactta tccgcagacc ttgagcttta ccctgcctgc actaggagca agcatctgga
    34081 aaatcaagcg tcgtcagaag caataagcta ttcattgctt acttagctgt ttcaaccaaa
    34141 agaagtcact acagtcatga aaggataacg aaatgaagaa tggaatgtta gccctcatat
    34201 tagcaggggg acaaggaact cgcttaggaa aattgacaca gagcattgca aagcctgctg
    34261 tgcaatttgg aggtcggtat cgtatcattg attttgccct atccaattgt gctaactcag
    34321 ggattcataa tgtgggggtt atcacccagt accagcctct tgccttaaat aatcatattg
    34381 gcaatggttc gtcatggggc ttagatggta ttaattctgg cgctacgatt ttacagccct
    34441 actctgcaac agagggaaat cgctggtttc aaggaactag ccatgctatc tatcaaaata
    34501 ttgattatat tgatagcatt aaccctgaat atgtgctgat cctgtctggt gatcatattt
    34561 acaaaatgga ctatgatgac atgcttcaga cgcataaggc taatatggct agcttgactg
    34621 ttgctgtgat tgatgttcct ctaaaggaag ccagtcgatt tggcattatg aacacagata
    34681 ccaatgaccg cattgtcgaa tttgaagaaa agcctgccaa tccaaaatca accaaggctt
    34741 caatgggtat ttatatcttt aattggcagc gccttcggac catgctggtt gacgcagaaa
    34801 aaaacaacat tgatatgtct gactttggtc agcatgtgat tccgtcttac cttgagtctg
    34861 gcgagcgtgt ctacacctat aactttaaag gctactggaa ggacgtcgga acgattgagt
    34921 ctctctggga agccaatatg gaatacatcg gtgaggaaaa tgccctagac agtcgtgatc
    34981 gttcttggaa gatttattct aaaaaccata tcgctccacc aaactttatc acagaggacg
    35041 ccgaggtcaa ggattctctg gtagtagatg gcagctttat ctctggtaag gtcaaccatt
    35101 ctatcttgtc taccaatgtg caggtaagaa agggagccga ggttaaggat tcctttatca
    35161 tgagcgatgt tatcattggt gagggtgcaa ggattacacg agctattatt ggtgagggtg
    35221 cagtcattgg tgatcatgtg atcattgatg gcagcaagga cgttcaagtc gtaggctata
    35281 atgaagtagt gggggtacca aatgaagatt gataaatatt ctgccattct aggcagctca
    35341 attggctttg ctgaaatgaa ggggctaaca gacacaagac cattagccaa cctacccttt
    35401 gatgggaaat accggctcat tgattttcaa ttgtccaacc ttgccaatgc aggtgtccgt
    35461 agcatctatg gtatttttcg tgggcaaaat atccgctcag tgtttgatca tatcaggtca
    35521 ggtcgtgaat gggggcttaa ttccttacta agtcattatt tccttggctt ttataacacc
    35581 aaggaggatt ctaaagaggc tgacaaggac tattatcagc agattttgac ctatttaaag
    35641 cgctcagggt cagatcagac catttacatg agctgtgata ttctctgcaa tattgagctt
    35701 gggcaggtta ttcatctgca caatgccaac catcgcaaca ttacggttgt ctacaagaaa
    35761 atgccgacca aggccatctc taaggctaac gatattttag atattgacga gacagatact
    35821 gttgttgaca ggcgaagtct gtctgagggg caggaggttg aaaaaatgtc agcaggcatt
    35881 tacatcgtca ataccccatg gttaattgaa cagatggaaa aagaagccga aaaagaaaac
    35941 cctcaaaagc tacgcttcct cttacgtgat ttgattgtgt cagagggcgc tcttggcttt
    36001 gaatatactg gctatcttgc caatattcac tctgttaaat cttattttga tgccaatatg
    36061 gacatgctgg atccgcataa gttttattca ctattatatg ctaatcagaa ggtctacacg
    36121 cgtgtcaaaa atgaagagtc aacctatttt gatgcggctt ctgaggtgaa caatgcccaa
    36181 tttgcttcag gaagcattgt caagggctat gtcgagcact caattgtctc tcgcaattgt
    36241 cgcattacct cacaggcacg tgttacaaat agtattttat tgccaaaggc agtgattggt
    36301 gagggtgctg tcattgatta tgctatcatt gataaatccg taagggttgc accaggtgtt
    36361 actattagag gaagcgctga ggagccaata gttgttgcca aggggactga ggttgttgag
    36421 gatatgataa aatgaagata atgtttgttg cagcagaggg agctcccttt gctaagacag
    36481 gtggcctagg cgatgtcatt ggggcattgc ctaaatcact tgttaaaaat ggtcatgagg
    36541 tgtctgtgat actgccttat tatgacgtgg ttgatcaagc ctttggtcag caggttgagg
    36601 acgtcttgta tttttatacg caggttggct ggagacgcca atacgtgggc attaaaaagc
    36661 ttgtcaagga taaggtgacc ttttacttta ttgacaatca aggttatttc tttagaggca
    36721 ggatctatgg tgattgggac gacggtgagc gctttgccta tttccagctg gctgccatag
    36781 aagcaatgga gaaaatcggg gttattccag atattttgca tgtgcatgat taccataccg
    36841 ctatgattcc tttcctattg aaagaaaaat accattggat tcaggcctat caagcgattc
    36901 ggacagtttt taccattcat aatatcgcat ttcaagggca gtttgatcct ggcatgctag
    36961 gcgatttgtt tgatgttggt atagagcgct acgaggatgg caccctgcgt tggcatgatt
    37021 gcttgaattg gatgaaagca gcagtcctat atgcagatcg ggtaaccact gtctcaccct
    37081 cttatgcgca tgaaattcag acaccagcct ttggacaagg cttggatcaa gtcatgcgaa
    37141 tggaggcagg caagctatca ggcattgtga atggtattga cactgactta tttaacccag
    37201 caagggatcc tcatttgcct gcttcatttt cagcagaaga cctatcaggc aaggcggcta
    37261 ctaaacaggc cttgcaggag cggttaggat taccagtcag ggcagatgtt ccattgattg
    37321 gtatggtttc gcgcttgacg gatcaaaagg gctttcagct tgttcttgag gaattaccgc
    37381 atatcttgca gcaggacgtt cagcttgtct tgttaggaac aggtgaccct gattatgagg
    37441 ctgccttttc atggtttgcc aaggcctatc cagaaaaact gtctgctaat attacctttg
    37501 atctgccatt agctcagcag atttatgggg cctgtgatct ctttttaatg ccaagtgctt
    37561 ttgagccctg cggactttcg caaatgatgg ctatgagata tggcgcgata ccgattgtcc
    37621 atgagatcgg cggcttgaag gatactgttg cctcctacaa tgcttatgaa aagactggaa
    37681 ctggttttgg ctttgatcag ttttcaggat tttggttaac gcagacgctc ttgtttgccc
    37741 ttgatattta ccataaccac aaggaggatt ggcagactat tcaacaacat gccatgacca
    37801 aggatttttc atgggataca gccagtctgg cctaccttga tttatataaa agcttactat
    37861 aacacagaaa aggaatggga atgcacgtca caaaagaaca atttattcga gattttaaag
    37921 ataccttaca tgaggaacaa ttgatcaagg ttcctgccgc aacagctgct gagcttttca
    37981 cctcattagc aaagcttatc cgtaaatact atacagatac ttggattgaa aggaatcgtt
    38041 ccttaaccga acagcagcaa aaaattgcct attatttttc gatcgaattt ttaccaggaa
    38101 gaatgctaga aacaaatctt cttaatttag gcattcttga tacagttaaa gaagcctttg
    38161 ctgacttggg aattgatttt caagcagtga agcatgcaga gcacgacatg gctctaggca
    38221 atggaggtct aggacgtttg gcagctgcct ttatggattc gctagcgaca acaggctatc
    38281 caggctttgg aaatgggctg cgttatcgtt atgggctgtt taagcaacgg attgtgaatg
    38341 gttatcaggt agaattacca gattcttggt ttggctctat tggtaatgtc tgggagatca
    38401 gaaaggatca tgacattgta gacgtcaagc tctttgggaa tgtttaccta aaagccaatc
    38461 aggacggtaa gctagcgcca atctatgagg gagctcaggt tttgagagct gttccctacg
    38521 atgttcctca gattggcttt gaaaatgatg tgattaacaa tcttcgcctc tgggacgtag
    38581 aaatcccaga agaacatgag cttgattacc caaccatcga gtcaagacgg gcagtcaagg
    38641 acattactgc cattttgtac ccagacgaca gcagctatga aggcaaaaag cttagattga
    38701 tccaagaata tttcatgacc agcgcaggca tccaaaccat tatcaaatcc tatttaaagc
    38761 agggcttgcc acttactgag cttcatcaaa aggtatctgt tcatatcaat gatacccacc
    38821 cagcagtagc tccagcagag cttatgcggc tcttgattga cgactatggc ttagaatggg
    38881 tagacgcctg ggcgacaacc gtaaaaacca tgagctatac caatcatacg attttgtcag
    38941 aagccttaga aaaatgggac gcagagctct ttaagactgt gctgccccgc gtttatcaaa
    39001 tcattttaga gattgatcat cgctttgttg ctgaaatggc gcaaaagggt attgatcctc
    39061 agatcattga aaacactaga atcgttaagg acaaccagat ttatatggct aatcttgcca
    39121 ttattggtgg ctattcggtc aatggcgttg ccaagctaca tacagagttg ttaaagacag
    39181 atacccttaa ggacttttat gccttgtatc ctgaaaaatt caacaacaaa accaatggta
    39241 tcgtgcaaag acgttggaca cagattgctg cgccagagct atcagcagct attgaccgca
    39301 cgattggcaa aggctggcgc aaggatattc accagcttcg acaattgagt caatttacag
    39361 aagatccagc tgtgctaaat gatttttatc aggtaaaaca agcagctaag cagcgcctag
    39421 ccaggtatat cctggaaaaa acaggtcttg aggtttcaac agaggctatt tttgatgtgc
    39481 aggtcaaacg cctacatgcc tacaagcggc agctcctgaa cgtcctgcat attatgaagc
    39541 tttaccttga tttgaaggct aatccagatt tagatatggt gcctagagtc tttattttcg
    39601 gcgcaaaggc tgcaccaggc tatcattttg ccaagtcggt gatcaaaatc atcaatgagc
    39661 tggctaatct cattaaccat gataccagtc tcaaaggaaa gctaaaggtt gtttttcttg
    39721 aaaattataa cgtgagtcta gcagagctca ttatccctgc ggcagatatt tcagagcaga
    39781 tttcactggc ctccaaggaa gcctcaggaa catcaaacat gaaatttatg atgactggtg
    39841 ctatcaccct agcgaccctt gatggggcaa acattgaaat caaagacgag gtcggagagg
    39901 aaaacattgt gatctttggt atggataagg atcaggtcta tgaccactat gccaagcatg
    39961 attattattc aagaggccta tatgagagcg accctcagat taaagcagta gtcgacgctt
    40021 ttgtcaatgg caccattcca aatagtcaac acgaaggtat ggaaatctat gatgccctaa
    40081 tcacgcataa tgatgaatac ttcttgctag aagacttttc ttcctatgta aaagcacagg
    40141 ctaagattga tcggctctac cgccaaaagg atagatggtc aaaaatgtcg ctcatcaaca
    40201 ttgcccattc tgacaagttt acatcagatg ataccatcac ccagtatgcc aaggacattt
    40261 ggcagctaaa acgctaatcc atcaaggaag aaaaagcatt agttacctta gattgaagag
    40321 agtgtctttt gagaccattt tcttcaatct tttttgattg caaaagacct tgggaatcag
    40381 atcagctgcc tgcctaatac tttggcctat caaggtattt tggaatttgt taatcttttt
    40441 gttataatag tggtgtgaag ctatttttta aatgaaaaag ccaacacttc aagatggtgt
    40501 taaagtaagg ttagtattag tctaagaaag cgtaaccaca ttaaagaaag ctgttgacat
    40561 tctcaatttt aaggaataga ataacaaagt aaaaaatttt taaaaggagt attctattat
    40621 gaatcctatt ttcgcattgg ctcttgcctg ctttggtgta tcacttgccg aaggcttttt
    40681 gatggctaat ctctttaaat cagcgtcacg ccaaccagaa attatcggtc aattacgttc
    40741 cttgatgatc ctaggtgttg cctttattga aggtaccttc ttcgttaccc ttgttatggc
    40801 cttcattcta aaataacagc ctatttgata tagaaaagga gggtattaaa tggaagaagc
    40861 taaagtaccg atggtagagc ttggtccaat aacctttaat ttgaccctac ttgctgtttg
    40921 tattgttact atcctactga tatttggctt tgttttttgg gcaagtcgtc agatgacatt
    40981 aaaaccaaaa ggcaagcaaa ctgcgttaga atatttaatc agctttgtta atggtattgg
    41041 ggaagagcat ttggatagtc atcttcagaa gtcttattcg cttttacttt ttaccatttt
    41101 tctttttgtg gcagttgcca acaacttggg cttatttaca aagctagaaa caaccagtgg
    41161 ctacaaccta tggacatcgc caacagctaa tttggccttt gacctagccc tatctctgtt
    41221 tgtgacgctt cttgttcata tcgaaggcat tagacgtcgt ggttttggcg cttatttaaa
    41281 acgctttgcg acaccttggc caatgactcc gatgaaccta ttagaagaat ttaccaactt
    41341 cctatcactt gctatcaggc tgtttggtaa tatctttgca ggagaggttg tgacaggctt
    41401 gattgttcag ctggccaatt atcgcctgta ttggtggcca attgctttcc ttgttaatat
    41461 agcatggaca gccttttcca tatttatttc ctgcatacaa gcctttgtat ttacaaaatt
    41521 aacagcaacg tatttaggaa aaaaagttaa tgaatcagaa gaataagaag ggaggacaaa
    41581 cgaatgtcag ttacaattgg tgagctcatt gggaatttta ttctggtaac aggctctgtc
    41641 atcgtcttgt tgctcttgat taaagccttt gcttggggtg ctatcgaagc tgttttacag
    41701 gcacgctcac agcaaatttc acaggatatt gaccaagcag agcaggcgcg tctcaacgcc
    41761 cagcagcttg aaaaggaagg tcaagccaat ctagaagcca gcagatcaga ggctagtcag
    41821 attgttgagg cagccaaaga aactggtaaa gcacaggaga cacgcattgt agcagaggct
    41881 acagaagagg cagatcgcct aaaagcagca gcgttgacag atatcgaaca cagcaagtca
    41941 gaggctattt cagccgttaa gacagaaatg tcagatttga cagttttact agcagaaaaa
    42001 attatgggag ccaatcttga taaggcggct caaagccagc ttattgatcg ctatcttgat
    42061 gatttaggag aggcttaatg accaaaaaag aacaagctct tatcgagcaa tatgcaaaaa
    42121 gtcttgtgca ggtctgtcag gagcgagaca ctcttgaagc actgcaggct gatgtgcttg
    42181 ccattttaga ggtttttaaa gctactaatc ttgctaagac attgtcaagc ttagcggttc
    42241 cacgtgctaa aaggcttgag ctagtaaggc agcttcaagg agataatatc gtttatctga
    42301 ataacttgct agaagttatg ctgcaaaatg agcgtgaagc ttatttatat caagtgcttc
    42361 taagggtttt atccgagctg gctagtgtct caaatcaata tgacgtgaca gttacatcag
    42421 cagttccttt aagtgaggag caaaagcagc gtgtgcgtac agtggtttca aagagacttg
    42481 cagtaaagac aggtcgctta atcgaaaagg tagatccttc tttaattgga ggatttatga
    42541 ttagcgtcaa taataaggta attgatacaa gcattcgtcg tcaattacaa gcatttaaaa
    42601 tgaatttaaa atagaaagtg gtgtgacttt tggcaattaa tgcacaagaa attagcgctt
    42661 taattaaaaa gcaaattgag aacttccagc caaatttcga tgtcacagaa actggagttg
    42721 ttacctatat tggtgatggg attgcacgtg ctcgtggctt agacaatgcg atgagtggcg
    42781 agcttcttga attttcaaat ggtaccttcg gtatggctca aaacctagag tcaaacgatg
    42841 ttggtatcat tattcttggt gatttttcaa cgattcgtga gggtgatgaa gtcaaacgta
    42901 ccggtaaaat tatggaagtg ccagtcggtg aagctctcat tggacgtgtg gtcaatccac
    42961 ttggtcagcc tgttgatggc ttaggtgaca ttgagacaac tggctttagg cctgttgaaa
    43021 ctccagctcc tggtgttatg cagcgtaagt ctgtttttga gtccttacaa accggtctaa
    43081 aggctattga tgctttggtt ccgatcggtc gtggccagcg cgagctgatt atcggtgacc
    43141 gtcagacagg taagacgtct gtagccattg atgccatctt gaatcaaaag gggcaggaca
    43201 tgatttgtat ctatgtcgct attggtcaaa aggaatcaac agttcggaca caggttgaaa
    43261 ccctacgtcg ttatggtgct ttggattata ccattgttgt aacggcttct gcttcacagc
    43321 catcaccctt gctgtttatt gcaccttatg ctggtgttgc gatggcagaa gagtttatgt
    43381 acaatggcaa gcacgttttg attgtttatg atgacctgtc taagcaggcg gtagcttatc
    43441 gtgaattgtc gctcttgctt cgtcgcccac caggtcgtga ggcctatcca ggagatgttt
    43501 tctacctgca tagccgcttg cttgagcgct cagctaaggt gtctgatgac ttaggtggtg
    43561 gctcaattac agccttacca tttattgaga cgcaggctgg ggatatctct gcctacattg
    43621 cgacaaacgt gatttcgatt acagatggtc agattttctt gcaagaggat ctctttaact
    43681 caggaatccg cccagctatt gatgctggct cgtcagtatc tcgtgtcggt ggctctgcac
    43741 agatcaaggc tatgaaaagg gttgcaggga ctttgcgtct tgacctagcc tcttatcgtg
    43801 agttagaagc ctttacacaa tttggctcag atctagatgc agcaacgcaa gcaaaattaa
    43861 atcgtggtcg tcgtactgtt gaaatcctaa agcagccact gcacaagccc ttgcctgttg
    43921 aaaagcaggt ggtcattttg tacgctttga cgcatggatt tttagatgat gttcctgtag
    43981 atgatatttt agcctttgaa gaagcacttt atgactactt tgatgcgcat tatgatcact
    44041 tatttgaaac aatccgtaca accaaagacc ttccgcagga ggctgagctg gacgttgcta
    44101 ttcaggcctt caaagcacag tcaaacttta aataaaagag gggggtacta gtatggcagg
    44161 ctctctaagt gaaattaagg ctaaaatcat ttcaaccgaa aaaacaagca aaatcactag
    44221 cgccatgcgt atggtttctt ctgcaaagct tgttaaatct gagcaagcag ctcgtgattt
    44281 tcaaatctat gcttcaaaga ttcgtcagat tacaacagac ttactgaaat cagacctgac
    44341 aacaggctca gataatccca tgctggtgtc tcgtcctgtg aaaaagacag gctatattgt
    44401 tattacctct gataaaggac tggtcggtgg ttacaattca aaaatcttaa agtccattat
    44461 ggacatgatt caggaatacc atgccgctgg cgattatgag attatctcaa ttggcagcat
    44521 cggctcagat ttttttaagg ccagaggtat gaatgttgcc tttgagctgc gcggcctagc
    44581 agatcagcca agctttgatc aggtcggaag gattatctct cagtctgtag gtatgtttgt
    44641 caatgagatt tttgatgagc tgtacgtctg ctacaatcac catgtcaata gcttgacgag
    44701 ccaggttcgg gttcagcgca tgctgccgat ttctgatttg gttgccgagg aggccgcaga
    44761 agaaggtgtc actggatttg aattagagcc aaaccgtcat gtgattttgg agcagctgct
    44821 gccgcaattt actgaaagct taatttatgg tgcgattatt gatgcaaaaa cagcagagca
    44881 tgctgctggc atgactgcaa tgcagactgc cactgacaat gccaagcatg tgatcaatga
    44941 tttgaccatc cagtacaatc gtgcgcgtca ggcggccatt acacaagaaa ttacagaaat
    45001 tgtagctggt gctaatgcac ttgaataagc ttattgtatg ctgatagcgc tctagcagag
    45061 acctattagc acttaatgtc atcttcaaag ctagatgaca tttgggatta atgagctagg
    45121 ggccttttac ccttagctac tcgaatttag aaaaattcag cttaatcccc tactatcgaa
    45181 tataaggaga aaaacatgag ctcaggcaaa attgctcagg ttgttggtcc agttgtagac
    45241 gttgtgtttg cgagtgggga caaactacca gagattaata atgcgttgat agtttataaa
    45301 gatggcgata aaaagcaaaa aatcgttctc gaggttgccc tagagcttgg agacggtatg
    45361 gtacgtacaa ttgctatgga atcaaccgat gggcttacac gtggattaga ggttcttgat
    45421 actggtcgtg ccattagtgt accagttggt aaagagactc taggtcgtgt tttcaacgtt
    45481 cttggtgaaa ccatcgacct agaagcacca tttgcagatg atgttaatcg tgaaccgatc
    45541 cataaaaaag caccagcctt tgatgaattg tcaacatcat cagaaattct tgaaacaggt
    45601 atcaaggtta ttgacctgct tgccccttac ttaaagggtg gtaaggtcgg tcttttcggt
    45661 ggtgccggag ttggtaaaac cgttcttatc caagaattaa tccacaatat cgctcaagag
    45721 catggtggga tctcggtatt taccggtgtt ggtgagcgta cgcgtgaagg aaatgacctt
    45781 tactgggaaa tgaaggaatc aggcgttatt gaaaaaacag ccatggtttt tggtcagatg
    45841 aatgaaccac caggagcccg tatgcgtgtt gccttgaccg gcttgacaat tgctgaatat
    45901 ttccgcgatg ttgaaggcca agacgtcctg ctcttcattg acaatatttt ccgctttact
    45961 caagcaggct cagaggtatc agcccttcta ggtcgtatgc cttcagccgt tggttaccag
    46021 ccaacacttg ccactgaaat gggacaattg caagagcgta tcacctcaac gaaaaaaggc
    46081 tctgttacct ctatccaagc catctacgtg ccagctgatg actacactga tccggcgccg
    46141 gcaacagcat ttgctcactt ggattctaca actaaccttg agcgtaagct gacgcagatg
    46201 gggatttacc cagcggttga tccactggct tcaagttcac gcgcgctgtc accagaaatt
    46261 gttggtgagg agcactatgc agtagccaca gaggttcagc gtgtcttgca gcgctatcgt
    46321 gaattgcagg atatcattgc tatcttaggt atggacgagc tgtcagaaga ggaaaagaca
    46381 ttggtaggac gtgcgcgtcg gattcagttc ttcttatcgc aaaactttaa cgtcgcagaa
    46441 cagtttacag gccttcctgg ctcttatgtt ccagttgccg aaaccgttcg tggcttcaag
    46501 gaaatcctag aaggaaagca tgaccacctt ccagaagacg cctttcgtgc tgttggacca
    46561 attgaggacg tgatcgaaaa agctaagaaa atgggctttt agtgaggtga tgccatgaca
    46621 caaatgactg ttcaggtggt tacgccagat gggatcaaat atgatcatca tgctaagttc
    46681 atctcagtaa cgacaccaga tggtgagatg gggatcttac ctaaccacat caatgtgatt
    46741 gctcctttac aggtgcatga aatgaagatt cgtcgtgtca gtgaagacga tcgcgttgat
    46801 tgggttgcta tcaatggtgg gatcattgag atcaaagaca acgtggttac cattgttgca
    46861 gattcagccg aacgtgatcg tgatattgat gttagccgag cagagcgggc aaaattgcga
    46921 gcagagcgtg acattgcaga ggctgaaacc actcatgata ttgatgaggt gcggcgtgct
    46981 aaggttgctt tgcgacgtgc cttgaaccgc atcaatgtta gtaaaaaata gtaaaatgag
    47041 tctaacctac caatttaacc aagacagagc gagtagcgct gcttaggaaa gggtgtagat
    47101 agactctttt atctttttat agaaaaaata ccctcttt
//
LOCUS       DARYLD010000009        44056 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYLD010000009 DARYLD010000000
VERSION     DARYLD010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44056
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(19..1290)
                     /locus_tag="TU651_000427"
     CDS             complement(19..1290)
                     /locus_tag="TU651_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL0896459.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1283..1891)
                     /locus_tag="TU651_000428"
     CDS             complement(1283..1891)
                     /locus_tag="TU651_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL0896460.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TU651_000429"
     CDS             complement(1932..3668)
                     /gene="pabB"
                     /locus_tag="TU651_000429"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL0896461.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3817..4287
                     /locus_tag="TU651_000430"
     CDS             3817..4287
                     /locus_tag="TU651_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL0896462.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4289..4633
                     /locus_tag="TU651_000431"
     CDS             4289..4633
                     /locus_tag="TU651_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL0896463.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4650..5078
                     /locus_tag="TU651_000432"
     CDS             4650..5078
                     /locus_tag="TU651_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0896464.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5276..7813)
                     /locus_tag="TU651_000433"
     CDS             complement(5276..7813)
                     /locus_tag="TU651_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0896465.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            8376..9329
                     /locus_tag="TU651_000434"
     CDS             8376..9329
                     /locus_tag="TU651_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL0896466.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9329..10075
                     /locus_tag="TU651_000435"
     CDS             9329..10075
                     /locus_tag="TU651_000435"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL0896467.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10324..11328
                     /locus_tag="TU651_000436"
     CDS             10324..11328
                     /locus_tag="TU651_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0896468.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11625..13811
                     /locus_tag="TU651_000437"
     CDS             11625..13811
                     /locus_tag="TU651_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0896469.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13889..14710
                     /locus_tag="TU651_000438"
     CDS             13889..14710
                     /locus_tag="TU651_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL0896470.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVSLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TU651_000439"
     CDS             complement(15006..15464)
                     /gene="nrdI"
                     /locus_tag="TU651_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0896471.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFSVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TU651_000440"
     CDS             complement(15860..17044)
                     /gene="sezV"
                     /locus_tag="TU651_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL0896472.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            17294..18898
                     /locus_tag="TU651_000441"
     CDS             17294..18898
                     /locus_tag="TU651_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0896473.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLSEIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGRDDY
                     YSLLMHLSSMLNDKPDGDRRQLTLASLLVDEIEKRIADGDRYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19121..21340
                     /locus_tag="TU651_000442"
     CDS             19121..21340
                     /locus_tag="TU651_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL0896474.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21355..21798
                     /locus_tag="TU651_000443"
     CDS             21355..21798
                     /locus_tag="TU651_000443"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL0896475.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21925..23217)
                     /locus_tag="TU651_000444"
     CDS             complement(21925..23217)
                     /locus_tag="TU651_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL0896476.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23972..24820
                     /locus_tag="TU651_000445"
     CDS             23972..24820
                     /locus_tag="TU651_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL0896477.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24970..26103
                     /gene="ugpC"
                     /locus_tag="TU651_000446"
     CDS             24970..26103
                     /gene="ugpC"
                     /locus_tag="TU651_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL0896478.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26287..27906
                     /locus_tag="TU651_000447"
     CDS             26287..27906
                     /locus_tag="TU651_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL0896479.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28015..28377
                     /gene="traF"
                     /locus_tag="TU651_000448"
                     /pseudo
     CDS             28015..28377
                     /gene="traF"
                     /locus_tag="TU651_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28491..28850
                     /gene="yajC"
                     /locus_tag="TU651_000449"
     CDS             28491..28850
                     /gene="yajC"
                     /locus_tag="TU651_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL0896480.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29024..29773
                     /locus_tag="TU651_000450"
     CDS             29024..29773
                     /locus_tag="TU651_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL0896481.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29783..30577
                     /locus_tag="TU651_000451"
     CDS             29783..30577
                     /locus_tag="TU651_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL0896482.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30609..31874
                     /gene="rseP"
                     /locus_tag="TU651_000452"
     CDS             30609..31874
                     /gene="rseP"
                     /locus_tag="TU651_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL0896483.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32144..34000
                     /locus_tag="TU651_000453"
     CDS             32144..34000
                     /locus_tag="TU651_000453"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL0896484.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34052..34609
                     /locus_tag="TU651_000454"
     CDS             34052..34609
                     /locus_tag="TU651_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL0896485.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34944..39341
                     /locus_tag="TU651_000455"
     CDS             34944..39341
                     /locus_tag="TU651_000455"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL0896486.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39463..39891
                     /locus_tag="TU651_000456"
     CDS             39463..39891
                     /locus_tag="TU651_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0896487.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40021..40566
                     /locus_tag="TU651_000457"
     CDS             40021..40566
                     /locus_tag="TU651_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0896488.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40745..41359)
                     /locus_tag="TU651_000458"
     CDS             complement(40745..41359)
                     /locus_tag="TU651_000458"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0896489.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            41724..43151
                     /locus_tag="TU651_000459"
     CDS             41724..43151
                     /locus_tag="TU651_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0896490.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            43417..43686
                     /gene="rpsO"
                     /locus_tag="TU651_000460"
     CDS             43417..43686
                     /gene="rpsO"
                     /locus_tag="TU651_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL0896491.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
     gene            complement(43778..>44056)
                     /locus_tag="TU651_000461"
     CDS             complement(43778..>44056)
                     /locus_tag="TU651_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL0896492.1"
                     /translation="WQYQHQSYHHFLETKGIRPSMSRKGNSPDNGMMESFFGIFKSEM
                     FYGLETTYQSLNELEQAITDYIFYYNNKRIKAKLKGLSPVQYRTKSFH"
BASE COUNT        12421 a         8752 c        10482 g        12401 t
ORIGIN      
        1 cttgtttttt tctttaggct agctgctaga aagcttatca attcgcgctt tattggcggc
       61 taaggctctt tcatattttc ctgtttcatt tgggttgaag taatttttct taaccaagtg
      121 atcagggaga tattgctgct tgacccattt ttctggatat gcatgagggt aaaggtagtg
      181 ctgagcattg cctagctcct tgctgccggc ataatgccca tcacgcaggt gtctaggaat
      241 gggaagatgg ccatgttgac gtaaatcagc gagagcagcg tccatagcca tataggcgga
      301 attggacttt ggtgacagtg ctagatcaat cacaacattg gcaatgagga tacgcgcctc
      361 tgggaagcca attttctggg cggcctcaag tgcagtgacg gtatggattt gagcttctgg
      421 attggcaaga cctatgtcct cataggcgat aatggtcaag cgtctagcaa gactcggaag
      481 atcgcctgcc tcaataagcc ttgcagcata gtgcaagcta gcattaacat cagatcctcg
      541 gattgatttt tgcaaggcag atagtatgtc ataatgtccg tcgccatctt tgtccattgt
      601 gatgtagctg cgctgcaaag aattttcaac agtattcaag ctgatatgac ggataccctc
      661 ggtatctggc tgggttgaca tgacagctag atcaagggat tggtaggcgg ctcggagatc
      721 tccatttgtc gctgtcgcaa taaagtcaaa agcagcctca tctagggtca catcaaaggc
      781 aaagcctctc tccttatcag tgatggcaag cttaagcgcc tgcttgatct cctcaggtga
      841 taggggctcc agctcaaaaa tctggactcg acttctgatg gctggagtaa ccgagaaaaa
      901 aggattccct gtggtagcac caatcataat aatgtgccca tgctctaaaa gtggtagtaa
      961 aaagtcctgc ttactcttat ccaatcggtg aatttcatca agcaaaagca caagtccacc
     1021 tgaaaactta gcttcctcag cgatttcttg gaggcgtttt ttattgtcta tggtagcatt
     1081 gaaggttcta aaggcgtact tggttgttcc agcaatagca ctagcaattg atgtctttcc
     1141 aataccggga ggtccgtaaa gaatcattga ggctaatcta ttggccttga ccatgcggtc
     1201 aatgattttt ccctccccga ccagatgctg ctggccgatg acctctgtaa tggttctagg
     1261 gcgcattctg atggctagat tatcaggcat tgtattcctc ccttccttgc ttttgttggc
     1321 tgtggtgctt tttaacaaca gccataaagt ttgcgatcat tgtcctaccg tcagctgttc
     1381 cgatgctttc tgggtgaaat tgaaggccaa acagtggcag ctgtctgtgt tcaaaggcca
     1441 taatctcatt gtcctcaaag tctcttgcgg taattacaaa gtcagctggc aggtcatcaa
     1501 caacaataga atggtaacgc atgacggtta attgctttgg cagctgttga aagagcttag
     1561 ctggtgcttg tctttcaagt atactttgct tgccatgcat gacgcgctta gcaaggcgta
     1621 gcctgccacc tagagcctca gcgatagctt ggtggccaag gcaaacgcca agcataggct
     1681 tttggtcata aaaggcccta atcaagctag gcatctgatt ggcggctttg ggccagccgg
     1741 gtccaggtga gaggactatg gcgtcagcct gcttcgcaag gtcaaatagt tttggatcct
     1801 gattggtcaa tacaatcgtt tgatcaaagg cactgaggta ttgggccaga ttataggtaa
     1861 atgaatcgta gttatcaatt aaaagtatca taaggtcctt catctagtag tgctgaggga
     1921 tcagcctggt actattgagg cagagtggtg tcctcaattg ttagtgagta gagtcctcgg
     1981 acagcattgc caccaaaaat ggcttcggcc ttgtctaaat ctgaaagctt tagctctttt
     2041 tcctgagcca gtccctgcct tagtaattct tgacggaaaa tgcctggtag aataccggct
     2101 gatacaggcg gtgtataaag ggtctgctcg atttgcacaa aaagattacc aatagaggtt
     2161 tcaagcaagg tcccatcagc agcaacaaag acttgctcat aaggcttgac gctcagatgt
     2221 ggtcgatgac tggttttaaa ataagtaaag ggaagctttt tgacatcgct tgattggcga
     2281 actaatcgtg cctttaaaaa gtctttttga agcggctcta agctttggtc tgtaaggcta
     2341 atctgcccgt ccttagcaat agcaatagtg agacgatagg ggctgctgtc ctttcccttg
     2401 agataggctt gcaaacgatc tgtcagaagc tcttcgtcat aggggtaggc aaaataacgc
     2461 gccgcctccc ttagtctgtt gaggtgctgg tctagatata ttaggctttg ttgttcgacc
     2521 ttggcagtgg ttttgatggt gaaatcaatg ctttgacggt tcagaaagga agatttttgc
     2581 ttgatttctt caaattcgtc ctgccagcag ctttcccagg taatcccacc gcctaccccg
     2641 tagatggcct gatcgtagct gagctgaatc gttcgaatag cgacattgaa gacacgtctg
     2701 ccatcaggca ggcaaatacc aatgctgcca cagtaaacgc cccttggctt aggctctaat
     2761 cggttaataa tagccattgt agacacctta ggagctcctg tgatggagcc acagggaaag
     2821 agtgcctgta aaatatcata aagacgacac tgatcctgca gcatgccgac aatggtagag
     2881 gtcatctgcc aaacggtgga atattgctcc aattggcaga gctgtgtgac tgtgacactc
     2941 ccagtttgac agatcttatt catatcattg cgtaataaat caacgatcat catgttttct
     3001 gaacggttct taggatcggc ctgtagccag tcatgctctt gttgatctag ttctaaattg
     3061 taaccacgct tggttgtgcc tttcatgggg cgtgtggtga tctggttttt ctcttgcttg
     3121 aaaaataact caggactggc tgaaatgaca gcaaagtcat cgtgagcaat gtaggcattg
     3181 tatccagctg cctgttcaat gaccaattga tgataaatgg ccaagctgtc cttagcgttt
     3241 agcctttggc tgagctgaat ggtatagttg acctgatagg tattgccctg cctcatctcc
     3301 tgatgaatct gtgcaatagc ctcttgatag gcttcctctt gtgtagcact tgtccagctg
     3361 tttggaatcg tcatgctgtc gtggtagagc ggaaagtcct cgagctgaca gctgtcatgc
     3421 actgtaaaat aagcaaaata ttcctgacca agtcttttat tgtgtgttgt tagctttttg
     3481 tcaaaacagg ctgctgcttc atagctgagg tagcccacaa catagtagcc cagatcttga
     3541 aattggttga cctgctcaag gacctgtccc acctgatcaa tctgcttagc tactaattcc
     3601 acgataggag cttgaaatat atagcgttgt cccagctcct taaaatcaat aatcgtcttt
     3661 atatgcatag cttgattata tcataaatgc gcttttcaga ctgattagga gggttgaaaa
     3721 gaagcctgtt agcaaccatc aacaatacaa gagagcaggg cttcttgatt tatgctacaa
     3781 tagtagcgga tattatttag aaaaaggaac aagagcatgg ctaaatatgg ctttttatca
     3841 gtattagaag aagagatgga caagcatttt cattatgact atgctatgga ttgggacaag
     3901 aaaaatcatg cggttgaaat cacccttgtt ttagaggctc aaaatcagtc agcagttgaa
     3961 accattgatg accaaggaca gctcagcaag gaagacattg tctttgagga ttatgtctta
     4021 ttttacaatc cggagaaatc acagtttcaa gcagcagact atctggtggc tattccattt
     4081 gagccaaaaa agggcttttc tcgtgaattt ttagcctatt ttgcccagtt tctcaatgat
     4141 gttgccattg aagggcatag cgatttgatg gatttcttag cagatgatag caagcttgat
     4201 tttagtctag agtggaacga ggaggccttt gaggaagggc aggtaggact agaggaaaca
     4261 gagctttata gctatccgag gtattaagat gctacatgag atgatgctga caccaagacc
     4321 atttgctatg attgaggcgg gtgtgaagac tattgaacta cggttaaatg atgagaaaag
     4381 gcaggctatt aaggtagggg attggatttg cttttattgt acagaggatc atagccatat
     4441 tctgcaagca gaggtcgtag ggttgcatta ttttgatgac tttgctaagc tttaccaagc
     4501 attgccttta gaaaaatgtg gttatcgtaa tgaagaattg gcactggctc ggccggagga
     4561 tatggaacag tactacagca aagagcagca agcccaatat ggcgttgttg gtattgagct
     4621 aaggctatgt tgattggtga gatctagtca tgaagctttt agataaaaca gtccattttt
     4681 ctggtgcaaa gttagccttg atcagtaacg gtaagatttt gaccatcttg cgtgacgcga
     4741 taccaacgat tccttaccct aatatgtggg atttaccagg aggtggtcgt gaaaatgctg
     4801 aagctccctt tgattgtgcg tcacgtgagt gctatgagga gttaggtctg gcactgacta
     4861 aggacgctgt cgtttgggaa agggtttatc cagggcttgt taatcctgac agccaatctg
     4921 tctttctggt ggctcttatg aatcaggaca tgatagatca tattgctttt ggtgatgagg
     4981 ggcagggtta tcagctgatg gctattgatg actttttagc agacgatcgg gtcattcctc
     5041 agctaaaggc tcgcttagct gattatttaa ggaaataggc agacttagct ggtacactaa
     5101 acagatcagc aaacaccact actatgtgat agctacgacc agaatcaaaa agacgattga
     5161 cctctgccca catgtggcta ggatcaatcg tctttgtttt tggggtggct aagtctttaa
     5221 tctggtaggc cagatcagct gagtagttga tattatcaat cagtcctgct atggcttagc
     5281 tgttgctagc tactgatgtg ctgctagctg tctctgactc acctaaaaaa tagctggctg
     5341 gcttatcact tactggcgtc ttaccaacaa gctcagggtc aggtgctaat aggtcgtcct
     5401 cgtcggagtc agaaacgggc gctacaaatt cttctagcca gcttccagtg ctgccagtgt
     5461 gattaggagt ttgaggctcc ttaggtagtg gatcacctgg tagccaggta ttccctgagt
     5521 gattactatt acctgtaaca tcgttgttgg ttattttatc aaagttgacg ttataaacaa
     5581 tatcctcagt gacttcctta tcatattcct cagttgaaat aataggctta ttgtaatcac
     5641 gcttgtagcc ggcatctggc tgtactgatg gtggtaggat accagctgta tgtaatgagt
     5701 gtcccttacg aacaaggtaa acggcagtct tacccttacc agctcggcta atcagctgtc
     5761 cgccctctcc tgccttaaag gcaacggcta catagtgtct cggatcgtgg aagtaataat
     5821 tagggtgtct gctaggatcc tctagatcag ttggcttgtc aggattaaca gcgatgtaag
     5881 gtccaatata aggagcagta gttccaaagg ctgctgagaa taggccagta aaggctacct
     5941 tatcgttttc attttgtgtg atagaaaatc tcttagcaaa atcagttaga ttaaagttat
     6001 tggcaaggtt cactccactg cggtattcaa taaattcata gcctggatct gggacgggct
     6061 cagggataac aagtccttgc tccttagctt ccttccaggt aagaccacta cgaacattgt
     6121 agaagaagcc tccttgagtc acgccgttaa gcttcaatcg cccattaaag attgtggtga
     6181 accagacagg aacataattt tctaagtcaa ggtctgaaac atcatcacct ggcccgtaga
     6241 cagccttggt aggctgcttt ctaaccttat caaaatctac atagaagcgt tgatgttctc
     6301 tgtccatctt gccagctgtt ggcaactcag cactccagcc cttaaagata cgcccctcat
     6361 gcttgattgc ctctggacgc tgaatgttca aatccttcca gtccaaatcc ttacgaacca
     6421 aatagtgcac acgtttagtt ttaatgccat taacctcaat gtcgccgtat tcactatttg
     6481 tactaaacaa cacatggata aagtttttga tgtttttgat gccctctggg tgatattttt
     6541 tatagacccc atcacgtgtt agattttcag atgaattttc cgtatagaaa ggaccataaa
     6601 cgagctgagt ttcgacctct agattggttg attctgtctt gacattgcgc tcaggatcat
     6661 ctggcaattc tgggtcaatc ttatagatgt gagcatggtc cccatgacta atggtcatgt
     6721 agttgccctc aattgagatg tcctcacgac gaaccttgaa gcgatccata aattctttga
     6781 tgagtctttc tttgcgctgt tcaaaggttt ctccgtctat ctttttgagg atctgttctt
     6841 ctggagtttt aaatggctta gaaagatcaa tatcctttag ccagatgacg tgcgtgtggt
     6901 cctcatgagg gtattcaaag ccgacctgac cgtctacatt cacctgctta atgcgtgctt
     6961 gatctacctt tagctccttg gcgagataag ctatataggc gcgatagtct ccttcctgag
     7021 gcttggtgtg gtcctttttc ttatattgct ccactaaata agcccatttg ctacgcttta
     7081 agtcctcaaa gctaataggg tgcaaatggt tcccatgctt caccaggatt ccagtgtcag
     7141 tgacaccgct aatgttggtg ccatcaaata agaagccatc actagttttg aagtcaattc
     7201 ctgggatacc cccctgctga tgaatgctag gtggtgttga tgggaagtga ggtgtggttg
     7261 atgcgatgtg gttgatggtt gctgatggca ggcttgattt gaggatatag tggtaatgat
     7321 ctccatgacg aacagtgtag ccataggcgt cctcagcaac aatgtcagct ggattaaaga
     7381 catagccgtc tccagcatga ccagttgaga ctactgatcc agaccttgcc gcttggttag
     7441 aagcaggctg tgcttccttg taatccttag gaatcaggta agcccatttt gtccccttca
     7501 aatctgagta aaagaagaaa tgcttgtgat cgccatgctt cacaatgata cctgtatctg
     7561 ttttgcgttc aatttgcgat tcgctggtca ataaaaagcc atcatcagtt gggacatcaa
     7621 tcccagggac ttggtgacgt tctctttttt tcgcagtctt actgcttttt tgttttttct
     7681 ttttcgtagc cttttggtgc tttttaggct cctgagaatg tcccttttgc gaatgcgttt
     7741 ggcaggctgt taaggcaagg ttgcaggcta acagcagtcc aacgagggat aaaaatcgtt
     7801 gatgttgttt catggttagt tatcaactcc ttccaacaat taacttaacc agttaatatt
     7861 attactggtt aagtatatca tttgacatct aagaatacaa tagattttat aaatttttta
     7921 atgaaattaa tctaatgacc taagagctgt ctggaagatg aaaggctttt tagctatttc
     7981 aaaggcttgg agcttcaaca ggcgaatcag ctattggttt ttctggattt acgagaaaga
     8041 gctgctcttt tttgatgtag ctggtataaa atatggtaaa atagggtcta tcaagagcct
     8101 atctaccttt agattggctg agatttgtta ggcaatgcgt ccctgataaa ggttgggctt
     8161 atgggacaat aggccttggt gctgtgtttg tccttagtat gaaacctctg agacggcaga
     8221 gcaggatccg gttggtttag gaccgcatta gcttatctta cgataaaaaa gaagcttgaa
     8281 aggaaaggct gctttgatct gatagagggt cactggtttt agggtttagg ctaggggcaa
     8341 gtgaccactg atgatatggc agcaagggta tcgttatgaa ggcatggcaa gagctgacaa
     8401 ttacagtcca tcgtgaggca gaagaagctg tttccaatct gctgattgag gctggcagcc
     8461 aaggagtcgc tatcaatgac actgcagact atatcggtca agaggaccgt tttggggagc
     8521 tttatccagc tgttgagcag tcagaaatgg ttactattac agcctattat ccaagctcag
     8581 ctgatattga tgacatcaga cagaccatta atcagggctt gaacaggcta aagcagtgtg
     8641 atgtggagct tggtgagtta accctgacca atcaagaatt ggctgaagag gattgggcgg
     8701 acaactggaa agcctattat gagcctgctc gtatcacgca tgatttgacg atagtcccca
     8761 gttggacaga ttatgaagcc acagcaggtg agaagatcat taggcttgat ccgggtatgg
     8821 catttggaac aggcacacac ccaacaacta agctaagcct gtttgccttg gagcaggtgc
     8881 ttcgtggtgg tgagacagtt attgatgtgg ggacaggctc aggtgtgcta tcgattgcta
     8941 gctctctgct tggcgccaaa gaggtctttg cttatgattt agatgatgtg gcggtgcgtg
     9001 ttgccaaaga caacattgcc ctcaatcaag ccactgacaa tatccatgta gcagctggag
     9061 acctgctaaa aggccttact caagaggcag acgttattgt cgccaatatc ttggcggata
     9121 ttttggtgca tgtgacagca gatgcttacc gtcttatcaa gtctgagggg tatctgatca
     9181 tgtcagggat tatttcagaa aagctggata tggtgaagca ggctgctctt aatgcaggct
     9241 tcttgctaga gactcacatg cttcagggcg agtggaatgc tcttattttc aaaaaaacag
     9301 atgatttatc aggagtgatt ggtggctgat gcagcagtat tttattaaag gcagggcaga
     9361 aaaaatcgtt cagctgaccg ataaggatac cattaagcat atgtttcaag tgatgcgctt
     9421 gacggataag gaagagctgg tgctagtctt tgatgacggc attaaacgct tggcaagggt
     9481 gtcagacagc tcagcctatg aggtggagct tatcaaagag ctggaagaaa accttgaaat
     9541 gcctgttgag gtgactattg cctcaggctt tcccaagggt gataagctag atgttatcac
     9601 tcaaaaggcg actgagttag gggcagcagc tatttggggc tttccagcag actggtcggt
     9661 ggtcaagtgg gatagcaaga agctagctaa aaagcaagaa aaattagcta aaattgctct
     9721 tggagcagca gagcaatcca agcgtaatcg cgtaccggag attcaactat ttgaccaaaa
     9781 gggtgagcta ttaaagcagc ttaagcagtt tgataagtgc tttatcgctt atgaggaagc
     9841 agctaaggca ggtgaaaggt cgacattggc gcgtgagcta gcaggtctta gcccaggtca
     9901 aaaagtcctc tttatctttg gaccagaggg tggtatttct tcaaaagagc tggctagctt
     9961 taagcaagca ggtgctatta ctgtgggact ggggcctcgt atcatgcgga cagaaacagc
    10021 accgctctat gccttgagtg ctgttagcta tgctctggag ctaatgtcta gctgatagtg
    10081 ctaataggag acagcacctt gtggctcagt gcttgacaga aaaaagagga gcatctgcga
    10141 ttatgctaat aaagcaccgc ttaacaaaaa gatcgctaag aaggagactg ccgcaaatca
    10201 aagggctagt ctagcccgcg taggtgcaga gctgtcgggc ctttgcagct tcatttgtaa
    10261 aaaatataac aaatcatctc aaaataaaga tactcgtcaa acggattggt agaggaggga
    10321 catgtggtta cgataaaaga tgtggcaagg ctagcaggag tttcgccttc aacagcttcg
    10381 cgtgccatca atgacagtga catgattagt caggcgacaa aggagcgtgt caaaaaagcc
    10441 atggaggcct tggattattc gcctaattat tcggcgcaaa accttgttaa gcgaaagtcc
    10501 aatactgtcg ggatcatttt gccggtgcgt gagggtcagg attcactggg aaataaccct
    10561 tttttcatgc agattattca aggaattgct gctgtttgta ccgatcaggg ctacatggta
    10621 gcccttgcga ctggacgtag tgaggccgaa ttgctaaaaa acgtgcaaaa catgatccgt
    10681 agtggcaata ttggcaagct gatttttctt tattccaaaa cagatgatca ggtttttgac
    10741 tttgtcaaaa ggcaaagagt ggattgtgtt gtcgttgggc aatcaacgac aaaggatcct
    10801 ggcaatgcta aatttgtcaa caacaataac catcaagccg gctatgatgc agcagcattt
    10861 ctccttcaaa aaggctatga ggctattgtc tatgcttata ctgacatggc cgaattggtg
    10921 caggcagagc gttataaggg ctatgcagag ctgatgactt caaaggctct ggcagctcaa
    10981 gccctttgtg tcacgctaaa ggacgatagg aaaagtcaaa agcagctgtt agaccaatta
    11041 gccaagcgct ctaaagttgc ctttgtagtc tgtgatgatg tgctagctat tcatttgcag
    11101 cgtctcatca agcaagtagc agctgacacc cagctagcaa tcgttagctt caataattct
    11161 gtcctagcgg agcttgcgag tcctgccttg acctccattg ctatttttcc ctatcagctg
    11221 ggagagcaag ctgctgagct ggtcttatca agcgcagcgc catcaccaca gccagtctta
    11281 gttcctcatc agatcattga aagagagtct acgcctttta ttgtttgatt taccgttaag
    11341 cctattccta agcaaagtac tgatagcttg cttaggaata aggcttttta tttaggaatt
    11401 tattttgttt gctaatagta ttaaagagaa gcaacgttta ctttagcatt ttcattgaaa
    11461 tcttcttaag aaaacgcttt acaaaacaaa aaaaggttgg taaaataagc ttatcaaaag
    11521 cgcaaacgtt tgcgttgaat gtgcttgttt ttaaaaagga attgagagtt catcagcttt
    11581 tagctggtta ttcttgattc ctagtccaaa aaaggagagg tcgaatgaaa acatcattca
    11641 aacaattttt tagcttcgag ttttggcaaa aattcgggaa atgcttgatg gttgtcattg
    11701 ctgttatgcc tgctgcaggt ttaatggtga gtattggaaa ttctctgccc atgcttaatc
    11761 aggagtcgca gcttttagcg acgcttggta atgtcattgc tcaggttggt tgggcagtta
    11821 ttggtaacct tcatttgctt tttgcccttg ctattggtgg cagctgggct aaggagcgtg
    11881 ctggcggtgc ctttgcttca gggcttgctt ttgttttgat taaccgtatt acaggggcta
    11941 tctatggcgt ttcttcagcc atgctgactg atccagaggc caagattaaa agtcttttgg
    12001 gcactgagat gattgtcaag gactacttta caagcgtctt agagtcacct gctctaaata
    12061 ccggtgtctt tgttgggatt atcgctggct ttgtgggtgc aacagcctat aacaaatact
    12121 acaattaccg taagctgcct gatgtgctgg ctttctttaa tgggaaacgc tttgttcctt
    12181 ttgtagttat ccttcgttca gctcttgtgg ccctagtatt agccttgatt tggccagtta
    12241 ttcagtctgg tattaatggc tttggcatgt ggattgcctc atctcaggac acagctccaa
    12301 tccttgcgcc attcttatat ggaacattgg agcgtctctt gctgccattt ggccttcacc
    12361 acatgctaac gattccgatg aactatacag ctcttggggg cacctatgag gtcatgacag
    12421 gagcagctgc tggaactaag gtatttggtc aagaccctct ttggctagcc tgggttactg
    12481 accttgttaa tctcaagggc tctaatgcgt caacctatca gcatttgatg gagactgttg
    12541 ttccggctcg ttttaaggtt gggcaaatga ttggtgcaac aggaacgctt atgggggttg
    12601 ccctagcaat gtaccgtaat gttgatgcgg acaaaaagca taaatacaaa atgatgttta
    12661 tctcagcagc ggcagcggta tttttgacag gggtcactga gccactggaa tacatgttta
    12721 tgtttgctgc gatgccatta tatcttgtct atgcccttgt tcaaggagct tcctttgcaa
    12781 tggctgattt ggtcaacctt cgtgtgcatt cctttggtaa tatcgagcta ttgacccgaa
    12841 cgcctatggc gattaaggct gggcttggta tggatttgat taattttgtc tgggtgtcta
    12901 ttctgtttgc tgtgatcatg tatgtcattg ctgactttat gattaaaaaa atgaagctag
    12961 caacagcagg tcgcctaggg aattacgatg ctgatatact agaaaacgat gatacaaagc
    13021 ctttgtcaca gcagtctatt gatggtcagt cacaggtcgt ccaaatcatt aatctcctgg
    13081 gtggacgtga gaatattgct gatgtagatg cttgtatgac tcgcttgcgt gtaacagtca
    13141 atgacccaag caaggttggc agtgaggagc attggaagca ggcgggtgct atggggctaa
    13201 tcatcaaggg cagtggtatt caggctgtct atgggccaaa ggctgatatt ttaaaatcag
    13261 atatccaaga cctgctagac tctggtgcag tcattccaga gccgaagcct gctcagcctg
    13321 ctgcctcatc atcacagcag acggacttta aaaacctaac agaggctgtt ttggcagtag
    13381 cagatggaga agtcttgcca atcacagcag tttctgatca ggtctttgca gctaaaatga
    13441 tgggagatgg ctttgctgtt gagccggcaa atggcgctat ctatgcgccg gtaacaggtc
    13501 tggtaaccca tgtctttcca accaaacatg cctttggctt gctgacagat agcggcctag
    13561 aggtgctggt tcacgttggt cttgataccg ttgacttgaa tggtgagccc ttcactgtca
    13621 aggttagtga gggtcagcgc gtatcggcag gagatctctt ggctgaggct gacctaactg
    13681 cgattacagc agcaggacgc aagacaacgg ttgttgtcgc ctttaccaat actacaagca
    13741 tcaaagctgt taaccttgtt gcgactggtc aacaaaaagc gaagaccctc gttgcacagg
    13801 tagagcttta agaataacca aagagagtgg tagatagcag tatgtcagac ctgcaggctg
    13861 ccacttctct tgtcgtatag gagaagatat gaccaagctc ttaaccctta acacacattc
    13921 ttggatggaa gccaatgcct taaaaaagct gttcgacttg gcagagcata ttttggctca
    13981 gaactatgac gtgatttgcc tacaagaaat caatcagctg attgacagcg aagcagcagt
    14041 gtcattatca ggctaccagc caattgcagg gacacctgcc attcatcagg ataactttgc
    14101 cctcttgctt gtcaattact taaaaaaacg tggccaaagc tactactggt cgtgggccta
    14161 caatcatatt ggctatgata tttaccatga gggtgttgcg atcttatcca agcagccgat
    14221 ccaagcctca gacattttag tctcagcggt ggctgacgag tatgattacc acaccagacg
    14281 ggctttactg gccaaaacaa ccattgatgg cagggaggca gcagttgtga gcctgcattt
    14341 gtcttggttt gatcagggct ttgtcggaga atggcagcga ttagaggcag ccctgcagca
    14401 gctagcctgt cctgtgctat tgctgggaga ttttaacaat ccaagtggcc aagagggcta
    14461 tgagatgatt ctaaaaagcc ccttagacct tcaggatagt catcaggctg cagactacgt
    14521 ctttggagac catagtattg ttgctgctat tgatggctgg gaggataaca aagaggcctt
    14581 taaggtcgac catgtcttta ccagtaaggt ctttaccatt aacagctcaa aggtgacctt
    14641 tgatggtggt gaagcaccgg ttgtcagcga ccattatggc ctagaggttg acctcagctg
    14701 gaagctgtaa caaaaaaagc cagcaggact tgatagactg ctgacactgt aagaaacaga
    14761 tggttatctt agctcttaga agtaagctta tcgcaaggct tctaagagct tttttgcatt
    14821 tatatttcat gagcatatga gaaagttgca gacaaatgct ggacacataa tcagactgtg
    14881 ggctagttac atcgtctgct ctgatttgtg tcagatagtg atgatctgtg ctgccttgtg
    14941 attggccaga tatttacctc atatcaatag cagaaagtca agtctccctc agcctatctc
    15001 ctagcttacg attgctgatc atcagtcagt ctagctacaa ttacctgtgc caagcgctca
    15061 atatcagcac tggtcccgcg tagttcgaaa tctcccagca ttggaaagcc aaagcgctta
    15121 gcatactgct tggctgttag acaatactgg tgattgaagt ttttgttgcc agagccgata
    15181 atccctaaac aacgcttggc attatcatgc gccgcgataa agtctcccag cggattggtc
    15241 aagatttcaa cctcccctga gtcaatcccg tttcctcctt caagataggt cggcaaaata
    15301 gcaacaaagc tctccttgac tgaaaaggtt tcgtgatgaa gctccttgat attgattgct
    15361 ttagtctgta tgtggtgctt ttctgccagg tattgcgaca agcgcctaac aaagctcagg
    15421 gtattgccgc taagactgat aaaaacaagg gtcaagtctg tcataaaaga ctcctttagc
    15481 aagattagtt tcctaaccag cttagcacaa tacccctgaa tacacaactc atatgacaat
    15541 gctctgcacg acaaacgcgc gaaacagtca tttccgaatg atagtataga cttaagcaga
    15601 tacattcacc gttttttcta tagtaaaagc tatagaaaat aagatatctt cttgaaatag
    15661 ctaaacattg acatacagaa agctttgttt tcttgctaaa accctatcat gcgtctgccg
    15721 tgcaatgctc tgacagctag cccactagtc acatcacata aaaaaggctt ggtgacaagg
    15781 acggtaagtc caaatcatca agtcttttta tggagagagc ttagtgttag ctgttacccg
    15841 aatcaagagg cccttgctgc taatgcttgc gattttgata ggtctttggg ctttctccgg
    15901 tatgcttttt gaaaaattta gaaaaatgtg agggatcagt gaagcccaac acgtctgaaa
    15961 tgtgattaat ggcataagca gagcgcagca atgtcttagc ctcttcaatt ttcatgtttg
    16021 aggtgtattg gtagatggtc aagcctgtat cacgcttaaa gatctgtctc agcttggact
    16081 cgctcatgtt aaaatgctgt gccagctcag cggttgtgac actcttatgc aggttgacac
    16141 tgatatattg gataatggca ttaaccgtag gagagacatg tttccagcgg ttgtcccgca
    16201 gctcactcac cttttgggtg taaaagacca gtgaggcatc acgaattttg agcacatctg
    16261 gcattgaggt tgccagctcg ctgtctctca tgaactcctc tcgtgaatgg taggcatcag
    16321 caatatccat accagattga atggcaatct gggctagtcg atcaaaggca atgatagaat
    16381 aatttttttc agagcgcagc gtatcaccac tcaccacagg gataaaggta tttcgtagac
    16441 tgaagatgat ttccttgagc ttgtgcacat caccctcttg aacaatgcta gataaatttt
    16501 tctcataatt gtagagacaa accttagatt cctgcttctt gacaaacata ttggcctttt
    16561 gcacctcgat attgtcggaa aaatccctaa tatagtgacg taaaggaggt gataacaaat
    16621 cctctatctt gccggaaaag aagtaatgga ccacaatcaa gaggtcacga atagcattca
    16681 aaggataaac aggtaaatgc tttagcgctt ggtaaagaat ctcttcttct tccttagtca
    16741 aatccttatc agcaacggcc accttaaaaa aggtcttatc caaaacatta cagcgccaag
    16801 ggccaattaa aatataatga tcctgataac ggtatattaa aaaaagctca ttatagcttc
    16861 cctgaaagaa aagattggtt gcctgttcct tgtccatttg cctaagcact gcttgaaaac
    16921 gataataaaa ttcaaaggta tcatcattcc aaaagctttc tgtcacctga tggtccttat
    16981 caaatactgt aattgataac ttcaaacagc cctgtagaga ttttactaac gacatagtat
    17041 ccatgctaag cgtcaccccc ttcataatcc tcacggtatc ttattctatc ttaaaattta
    17101 agaaaagcaa ggatatgcac ttataatgaa aaaatagaca taaaaaacaa taatatacat
    17161 tcttgcttat taaataaaaa tgacaatgta ctgcataaag aagttcctgt cattaaaata
    17221 aaagtgccat gaggttataa tagtatggta aaacaaaaaa gtgtgcccat aacgggtaga
    17281 gaggaattga catatgtttt tgagaaataa caagcaaaaa tttagcatca gaaaactaag
    17341 tgccggtgca gcatcagtat tagttgcaac aagtgtgttg ggagggacaa ctgtaaaagc
    17401 gaactctgag gttagtcgta cggcgactcc aagattatcg cgtgatttaa aaaatagatt
    17461 aagcgagata gccataagta gagatgcctc atcagcccaa aaagttcgaa atcttctaaa
    17521 aggcgcctct gttggggatt tacaggcatt attgagaggt cttgattcag caagggctgc
    17581 gtatggtaga gatgattatt acagtttatt gatgcacctt tcatcgatgt taaatgataa
    17641 acctgatggg gatagaagac aattaacttt ggcttcatta cttgtagatg aaattgaaaa
    17701 gcggattgct gatggagata ggtatgcaaa acttcttgag gctaaacttg cagctattaa
    17761 atctcaacaa gaaatgctta gagaaagaga ttcccaactt cgaaatctag agaaggaaaa
    17821 agaacaagaa ctacaaaaag ctaaagatga gcgtcaagct cttaccgaat cattcaacaa
    17881 aactttatca agatcaacaa aagagtataa taaactaaaa acagaacttg caaaagaaaa
    17941 agaaaaagca gctaagatga ctaaggaatt agcagataag ctaagcaatg ctgaagcaag
    18001 tcgtgataaa gcctttgcag tatcaaaaga tttagcagat aaactaagta gtgctgaagc
    18061 aagtcgtgat aaagcttttg cagtatcaaa agatttagca gataaattgg cagctaaaac
    18121 agcagaagct gaaaagttaa tggaaaacgt tggtagtcta gaccgcttgg tagagtctgc
    18181 aaaacgtgaa atggctcaaa aattagcaga aattgatcaa ttaactgctg ataaggctaa
    18241 ggctgatgca gagcttgcag ctgcaaatga caccattgca tcacttcaaa cagagctaga
    18301 aaaagctaag acagagcttg ctgtttcaga gcgtttgatt gaatcaggca aacgtgaaat
    18361 tgctgagcta caaaaacaaa aagatgcttc tgataaggct ttagtagaat cacaagctaa
    18421 tgtagcagag cttgaaaaac aaaaagcagc atcagatgct aaggtagcag agcttgaaaa
    18481 agaagttgaa gctgctaaag ctgaggttgc agatcttaaa gcacaattag ctaagaaaga
    18541 agaagagctt gaagccgtta agaaggaaaa agaagcgctt gaagctaaga ttgaagagct
    18601 caaaaaagct catgctgagg aactttcaaa acttaaagaa atgcttgaga agaaagacca
    18661 tgcaaatgca gatcttcaag cagaaatcaa tcgcttgaag caagagctag ctgacaggat
    18721 taagtcattg tcacaaggtg gtcgtgcttc acaaacaaac ccaggcacta caactgctaa
    18781 agcaggtcaa ttgccatcta ctggtgagtc tgctaaccca ttcttcacta ttgcagctct
    18841 tactgtcatc gctggtgctg gtatggctgt ggtgtctcct aaacgcaaag aaaactaagc
    18901 tatttcctct ttccccaatg gacaatagcc gaaataatag agcgactatc gttctaacac
    18961 aaaagcaaca gtctcctgtc tgttgctttt tgtgatatta gggctcatca gtctaggcta
    19021 atggttttct gcgctttatc tgcagctttg aggattcctt cttttgcttt tacagtgaaa
    19081 gtgttaaaat aggaaaaaca actagtaatt gaggaagtaa atggttaaag aaatcaattt
    19141 atcaggagag gaagtagttg cccttgctgc caagtacatg acagacggtg acgtcgagct
    19201 tgtgcaaaag gcgcttgatt atgcgacagc tgctcatttt taccaggtta gaaagtcggg
    19261 ggagccttat attgtgcacc ctattcaggt agcagcaatc ctagcagacc tgcatttgga
    19321 cgctgtgaca gttgtctgtg gctttttgca tgatgtggta gaggatactg atattactct
    19381 agaggacatt gagtttgact ttggtaagga cgttcgtgac attgttgatg gggtcacaaa
    19441 gcttggtaag gtagaataca agtctcacga ggagcagctg gctgaaaacc accgcaaaat
    19501 gctcatggcc atgtcaaagg acattcgtgt gattttggtc aagctagccg accgactgca
    19561 caatatgcgc accctcaagc acctccgtaa ggacaagcag gagcggattt ctcgtgaaac
    19621 catggaaatc tatgccccgc tagcccatcg cttggggatc agtcggatca agtgggagct
    19681 ggaggatcta gcttttcgct acctcaatga gatcgaattc tacaaaatct ctcatatgat
    19741 gagagaaaag cggcgggagc gcgaagcttt ggttgatgat attgtcacta agattaaagc
    19801 ctacaccacc gatcaagggc tttatggtga tgtctatggc cgtcctaagc acatctactc
    19861 ggtttaccgg aaaatgcgtg acaagaaaaa gcgctttgat cagatatttg acttgattgc
    19921 gatccgttgt gtcatggaga cacaaagtga tgtttacgcg atggtcggct atattcatga
    19981 gctctggcgt cccatgcctg gccgcttcaa ggactacatt gcagcgccta agaccaatgg
    20041 ctatcagtcg attcacacga ctgtttacgg gccaaaagga ccgattgaaa ttcagattcg
    20101 gaccaaggaa atgcatcagg tcgctgagta tggggtagca gcccactggg cctacaaaaa
    20161 aggtattcgt ggcaaggtca atcaagtcga gcaaaaggtt ggtatgaatt ggattaagga
    20221 gcttgtcgag cttcaggctg cctcaaatgg cgatgctaag ggctttgttg actcggtgaa
    20281 ggaggacatc ttttcagagc gtatctatgt gttcacaccg acaggagcag tgcaggaatt
    20341 gcccaaggat tcaggcccta tagactttgc ctatgccgtt cacactcagg ttggtgaaaa
    20401 ggcgacagga gccaaggtca atggccgcat ggtgcccttg acagccaagt taaaaaccgg
    20461 tgatgtggtg gaaattgtca ccaatccgaa ttcctttggt cctagtcgtg actggattaa
    20521 gctcgtcaag accaataagg ctcgtaacaa gattcgccaa ttctttaaaa atcaggacaa
    20581 ggagctgtct atcaataaag gacgtgagct tctggttagt tattttcaag agcagggcta
    20641 tgttgccaac aagtaccttg agcgtaagcg tattgaggag attttaccaa aggtcagtgt
    20701 taaaagcgag gagtctctct atgccgctgt tggctttggc gatattagcc cagtcagtgt
    20761 ctttaataaa ttaaccgaaa gagaaaggcg tgaggaggag cgtgccaagg ctaaggctga
    20821 agctgaggag ctggttaagg gcggtgaggt caagcatgaa aacaaagaga ttctcaaggt
    20881 ccgcagtgaa aatggcgtga ttatccaagg ggcgtctggg cttctcatgc gtatcgccaa
    20941 atgctgcaat cccgtaccag gagatgtgat tgaaggctat attaccaagg gacgaggcat
    21001 tgctattcac cgcgcagact gtaataacat caagagtcag gacggctatc aggagcgtct
    21061 cattgaggtt gagtgggatt tggagcattc tagcaaggat taccaagctg agattgatat
    21121 ttatggttta aatcgtatcg gcctgctcaa tgatgtcctg caaatcctat ctaacgccac
    21181 caagagcatt tcaactgtca atgcccagcc gaccaaggac atgaagtttg ccaatattca
    21241 tgtgagcttt ggcattccta atctggctca gctgacagct gttgttgaaa aggtcaaggc
    21301 ggttccagat gtttacagcg tcaaacgaac caacggataa aaaggagacc aaccatgaaa
    21361 attgtgattc agcgcgtcaa ggaagcctca gtgtcgattg atgggaaaat agctggcgct
    21421 attgatcaag ggctgctgct gcttgttggc ataggtccag atgatcaggc agaggatata
    21481 gactatgcag tgcgtaaaat cagtcatatg cggatttttt cagaccccga gggcaagatg
    21541 aaccgatcca ttcaggacat tgagggcagt gtcttgtcta tctcgcagtt tacgctatat
    21601 gctgacacca aaaagggcaa ccgacctgcc ttcaccgggg ctgctaagcc tgacagggcc
    21661 agccagcttt ataacagctt caacgctcag ctagagcagc ttgtaccggt tcagcgaggg
    21721 gtctttggtg cggacatgca ggttagtctg atcaatgatg gcccagttac gattatccta
    21781 gatacgaagt atcgataact gcctagcgat cgatcgtttg cttaggagag tcatataaag
    21841 gaaaaacaaa aagacgagtg gtatgagaag cactcgtctt tgtcgtttat gctgctgtgt
    21901 tgaagctagc tagggctact agtcttattt ttgcaggtct ttgtagactg cgatgaattc
    21961 tgtctcagaa attggggtta agctgccagt gaattggtaa gaagtaccat ttttagcttg
    22021 gaaagtatta ggtaaacctt taaggtattt gtcgatagtc tcagtggtaa ttgcttcgtg
    22081 tgttttaaag gtgtattcgt taatcagctg ctgctgtttg tcctgttggt aaatagtaac
    22141 tgaacgatag gttgtgctat agtcatcgtt aatatcctta gaaataaaat aggtttctac
    22201 aacagaatct gaatgtgtcg catagctaat gggattgttg acgtcatact ttgaattata
    22261 tacttgagct atcctgttag aatctatgat atagttaaag tcctcatcgc gatcagcatg
    22321 gtagaccatg cgttcactag ctccactgta aatctcaccg ttatggcttt gatgagttat
    22381 atcaggatcc tgcgtgactg ttgtactgat tcgcttgacg agctgatacc cgtctttgaa
    22441 agcctgagtg gtttcaaaag cctttttagc agcttcaaag agctcctcag aagagaccct
    22501 gctgccatag tatcttaacc cggtaagtcc ttctttacca aggctgtcag ttacatcaac
    22561 attaacaagc tgcccattgt cttttttgag gaatttaacg tgctgtgtca cagctacggc
    22621 atctgaatct tggattgggt ttcctgcctt atctgttacc ttaatgtcct tgagagctac
    22681 cttgctaact ttttccacaa ggacctgacc cgtcaagatg tatgtttggt ctttttgatg
    22741 atactgtcct ttgattggtg tcgtaaaatg gtctgtgcta agtatttcag ctgtagaagc
    22801 ttttgttaat ttggcatttt tcaaactaat gaccttaaag ctttctgctg aaggatctat
    22861 gacgtcttga actagcttta tcatctcatt tgtggtgtag gttttgccat attctagtct
    22921 aatatcctga taatgtggag atacgatggt gtgattagtg ttatctactc cagtgatatt
    22981 gaccatgagg tacagtcctg tggtttcttg atagtctttt gaatggattg gcttagtggt
    23041 gtcctcgtat ttatagtgat ttgctaccct actagagctt gaccatgccc acccaacttt
    23101 gtaatggttt gctttaacgg caggtgctcc caaggtcatg gtgaatagtc caatgactac
    23161 agttcctatt tctaaaggtg ttttcccaag gtgatacagt ctttttgaag tcaacatatt
    23221 tcaaacctcc ctaaatcctg tcagtctcta tagttataaa aatacagaga atcgttagaa
    23281 gaattaatgt ttcatgccgg caagatgagt gtaacaaaag attggtgccg atacaagaag
    23341 atggagatta gagcatctgg tttcaatgag agttacataa tagcagaagg ttttttcact
    23401 atgagagcta atcgtcttaa aatggtataa tagcaagtga ataggctatc taactggttt
    23461 aacagccatt tttagagaag cttaatagta ttgctgataa gtgactcgta tctccatatt
    23521 gcttttcaaa ggctatgtta gctatgataa gcgtgaccag gctatcggaa aatccagtgt
    23581 tcttaaaggc tttgaagctc tggctttgaa ccttagctct ggtgtttcta tgaaaatgac
    23641 ttgggccttg taccagataa gaatgaagtc aaattgaggt tttttgacaa aatgtttgag
    23701 taaatacaag ttcatagaag tctaatgtat aaaaatacaa ttgtatcgcc ataatctgaa
    23761 tgaccaaacc attaaaaaaa taaaattttt aaacattttg gaaaacgctt tcaaaactaa
    23821 aaagaactgt cctatagtca ttgcttagca ttaaagcaag gtgtgaaatg ttatcatatg
    23881 gagaaatagg ctgtcttgtg ctgtatctgt gccaaaaaag aatgcttgtt tttgtgatat
    23941 aatgtgacta agaaacctga aaggaatgct tatggcatta aaagactatt ttcctgatat
    24001 gcaagagggt gcatttcctc tggctgacca agattggatt agcgttgagg ttggggagca
    24061 gtacctccat ttccccaaat ccagcttgtc agagcgagag cagcttttgc ttggtttggg
    24121 gcggcagcgc aaagagccgt ccaaggatca gaaatctcct tggtatcatt atttgattct
    24181 gggccaaggg gagcagccgg aggagtttca gggttgccag ttcatctata tcaaccatca
    24241 atgtccttta gcaggtgatt tgattgagct tctaaagggg atcatagagg gagttgaggc
    24301 tgttttgccc attagccaga ccaggacagc ttttttggtc tgtcaccata gccgttcaga
    24361 cctttttcag ctcttagcaa atttattgcc cacgattgag agcgattttg gtttggcctt
    24421 gatgattttt atcggtaatg gctggtatca ggtgtcagga aatgccttga gagactattt
    24481 taaggaagaa aatgctgtgt ttacagctta tcttgctgag cactctgcca gtcgcttgct
    24541 gaccttttca gaggtcatgc tctggtcact cttagcaaac agtggtttgc cagccttgtc
    24601 aaagcatttt agtcagctgc ttttagccaa taaagaggtc atggatctgg tgctcgccat
    24661 gtggcaggag catggcaacc tggtacagac agcccagcgc ttgtatattc atcgcaattc
    24721 gctgcaatat aagctggata agtttgctca gcagtcaggt ctctatttaa agcagctaga
    24781 tgacttggcc tttgcttatc tatttatact gaagcattag atttgtgcag ggtgcccaaa
    24841 gacatttggg cgttttgtct atatgatgaa aacgctatct ttgctataat aaaagcatca
    24901 aataaaaagt gtcagggttg ctagcattgc agtcagctag cagcctatct gacccattag
    24961 gagtaacgca tggttgaatt aaacttaaag cacatctata agaaataccc aaataccaca
    25021 cactatgctg ttgaggattt cgatttagac attaaggata aggaatttat cgtttttgta
    25081 gggccttcag gctgtggtaa gtcaacaacg cttcgtatga ttgctgggct tgaggatatt
    25141 tcagagggtg aattgaaaat tgacggtgag gttgtgaatg acaaatcacc aaaggaccgc
    25201 gatatcgcga tggttttcca aaactatgcc ctttacccgc atatgaccgt ttatgacaac
    25261 atggcctttg gtctcaagct acgtaaatac aaaaaagatg atattgatcg tcgtgtcaag
    25321 gaagcagcag aaatccttgg cttgacagaa tttttagaac gtaagccagc agacctttct
    25381 ggtggtcagc gtcagcgtgt ggctatggga cgtgctatcg tgcgtgatgc caaggtattc
    25441 ttgatggacg agcctttgtc aaacctagac gctaagctgc gggtgtcaat gcgtgctgaa
    25501 attgcgaaaa ttcaccgccg tatcggctca acaacaatct acgtaacgca cgaccagacc
    25561 gaagcgatga ccttggcaga tcgtatcgtt atcatgagtg ccactaaaaa ccctcaaggc
    25621 aacggtacaa tcggaaagat tgagcaggtt ggctcaccac aggagctcta taacctaccg
    25681 gccaataaat ttgttgcagg ctttattgga agccctgcga tgaacttctt tgaggtggtt
    25741 gtcaaggacg gtcagatcat cagtgaggac gggcttgata ttgctattcc agaaggtcag
    25801 gctaaaatgc ttgaagcagc tggctataag ggcaagaagg ttatttttgg tatccgtcca
    25861 gaagatattt caagcaacca aatcgtgcat gacacctatc caaatgccaa tgtcacagca
    25921 gaggtcttgg tttctgagct gcttggatct gaaaccatgc tttatgttaa gcttggtcaa
    25981 acagagtttg cttcacgagt tgatgcgcgt gacttccaca atccaggtga aaaggttagc
    26041 ttgaccttca atgttgctaa ggggcatttc tttgatctag aaacagagca agctattcgc
    26101 taataacacc tcctagaata aaatcctcat cttgcttgag gattttttaa caaaagaaaa
    26161 tgcaagcgat tgcgctatca aaaagaaaaa gggatttatc ataaagacaa cagatgttct
    26221 gtagtgctag gcgatcataa tgatggcacg aaatagcagg agactgttta gtaataagga
    26281 gatatgatgg aaaaacactg gtggcataaa gcgacaattt atcaaattta cccaaggtcc
    26341 ttcatggata caagtgggaa tggtattggt gatttaaaag gaatcacagg taagctggat
    26401 tatctacagg agctagggat cacagctatt tggctgtctc cagtttatca atcaccaatg
    26461 gacgataacg gctatgatat ttcagactat caggccattg cagctatttt tggtgatatg
    26521 gctgatatgg acgagctgct tgatgaggcc aagcagcggg ggatcaaaat catcatggat
    26581 ttggttgtca atcacacctc tgatgagcac gcttggtttg tggaggcaag agaaaatcct
    26641 gacagtccta aacgagatta ttacatttgg cgtgatcagc ctaataatct catgtcgatc
    26701 ttttctggct ctgcttggga atatgatgat gcctctgggc agtattatct gcacatattc
    26761 agtaaaaaac agcccgactt gaattgggaa aatgctgaat tgcgtcaaag catttatgac
    26821 atgatgaatt tctggattga taaggggata ggtggctttc gcatggacgt cattgacctg
    26881 attggtaaga ttccggattc tgaaattaca ggcaatggcc caaggctgca tgaatacctc
    26941 aaggagatga accaggcaag ctttgggaat catgacctga tgactgttgg tgaaacatgg
    27001 ggcgctacac cggaaattgc tcgtcagtat tcacgtcctg aaaataagga gctgtcaatg
    27061 gtctttcaat ttgaacatat cggcttgcag cataagccaa atgcttctaa atgggattac
    27121 gcagctgagt tgaatgttcc ggctctcaag gagattttta gcaagtggca gacagagcta
    27181 aagctaggtg aaggctggaa ctcccttttt tggaacaatc atgacttgcc tcgtgtcgtc
    27241 tccatttggg gaaatgatac agtatataga gagaagtctg ccaaggcaat ggctattttg
    27301 ctgcatttaa tgcgtgggac accttatatt tatcagggtg aagagattgg catgaccaat
    27361 tacccctttg agcgcttgag tgatgtgaat gatattgaat cactgaatta tgccaaggag
    27421 gctatggcta atggcatgtc agaggaggct gttcttgatt gtatttgtag ggtgggtcga
    27481 gacaatgcaa gaacaccaat gcaatggagc agtcaaaaga acgccggctt ttcaactgct
    27541 gatcagacct ggctgcctgt caacccaaat catcaagaga ttaatgtggc tagtgctcta
    27601 gctgatcctg attctgtttt ttacacctat caaaagctta ttcagctgcg tcagacacag
    27661 gattggctgg tggaggcaga ttatcagctg ctggaaacat cagataaggt ttttgcctat
    27721 aagcgtcagc ttggtagaga gacttacctt gttgttgtca atctgtctaa tcaagagcag
    27781 ttttttgaag aaagtcttca taaggcccaa gtgattatca gcaataccga tgtgcaggca
    27841 gtcgtagaaa gtcaacagct ggagccttgg gacgcctttt gtgttaagct tgatgagacc
    27901 ttgtagccta gctgcttgct gtgcctcagc tcaataatcg tagcgattct ttgagaattt
    27961 tgacaaattg ctgtatgatt agtagaagaa ttagatacaa aagaggaggc tgagatgacc
    28021 gttgaagaaa ccatgacctt tgcaaaaagc attgcagcat ttagataggt agagattagt
    28081 gaggtagtca ctaggctagc agcaggtgag gacatcaccg tctttttagg cagagcgacc
    28141 tgtccttatt gtcgtcgctt tgcacccaag ctagcaagcg tagcaaggca ggagcataag
    28201 gatattttct ttgtagatag tgaagactca acagagcttg cagacctgca ggcctttcgt
    28261 gagcgctatg ggcttgctac tgtgcctgcc ctgctcatta gtcgtcatca ggaggtcaag
    28321 gcagtctgtg attctagctt gactgaggaa gccattttgg ctttcctaga gcagtgacag
    28381 acagctaatt atctggtgca agtaatagaa atgtaatcag tcatgtcttg ctatgtgagt
    28441 ccaaatctgc tatagtagga catgactttt agacgaaata aggagatatt atgggcttac
    28501 caacaatttt aatgtttgtt gtcatgattg gtttaatttg gtttatgcag cgtcagcaaa
    28561 aaaagcaggc gcaggagcgc caaaatcagc ttaatgcgat tgaaaaaggc gatgagattg
    28621 tgacgattgg tggcatgttt gcagtggtcg atgaggttga tttagcagca aagcgaattg
    28681 tcttagatgt tgatggtgtc tatctgccat ttgagctatc agcgatcaag cgcgtggtcg
    28741 aaaaaggaag tgcagtgaca tcagctgatg tggatacgac agagactgca gttgatgaca
    28801 cagcggttga ggcttcagac gaagctgaat cagctattga gacaaattaa gaaaatgagg
    28861 tctgaagcat tagtgtttca gactttttta ggtgatgata gcaggtagcc agacagagct
    28921 gtcatgtgct atggaaatat cgtctacaac gagaaaaagc gagccaaacc gcatgaaata
    28981 tggtaaaata tgaggtaagt atgcttgtga ataaggaaaa aacatgtttg gattaaaagc
    29041 gaagtcaaaa aaaatcgttt tggataggat tccaaagcac attgggatca tcatggatgg
    29101 taatggacgc tgggcgaaaa aacgcttaaa gccgcgtgtc tttggacata aggcgggtat
    29161 ggacgctttg caggaggtaa cgattgcagc ttcagattta ggggttaagg tgttaacagt
    29221 ctatgccttt tcgacagaaa attggtcaag accacaagat gaggtgagct tcattatgaa
    29281 cctgcctgtt gagttttttg ataagtatgt gcctgagctg cacaaaaata atgtcaaggt
    29341 gcagatgatc ggtgagacca accgcctacc taaggataca ctaaaggcct tggaagcagc
    29401 tattgctaag acaaggcaaa atactggctt gattctaaac tttgctctta attatggggg
    29461 tcgcgcggaa atcaccaatg ctgtcggtct cattgctcaa gatgtcctag acgccaagct
    29521 gaaccctggt gacattaccg aggatttgat tgccaactat ttgatgacgg atcatttgcc
    29581 ctatctctat cgcgatcctg accttattat cagaacgagc ggtgaattgc gcttgagtaa
    29641 ttttatgcct tggcaatcag cctatagtga gctttacttt acgccggtgc tgtggcctga
    29701 ttttaaaaga gctgaactac taaaggccat agaggattat aaccatcgtc atcgccgttt
    29761 cggtgctatt taaggagaga gtatgagaga acgtttcatt tggggtggtg ttgcagctgc
    29821 tgttttccta ccctttttac tcattggcag cttacccttt caattgtttg taggtgtgct
    29881 tgccatgatt ggtgtatcag agctgttaag aatgaagagg cttgaggtct tttcctttga
    29941 gggtgttttt gccatgctag cagctttcgt tttgacagtg ccgttggatc attacctgac
    30001 ctttttgccg atggacgcta gttttgcttg ttacgggctg ttggtgtttt tccttttagc
    30061 aggaatagtg attagcagcg attcttatgg ctttgaggat gctagctttc cgattgcagc
    30121 tagcttatat gttggtattg gctttcataa tctggttaat gcgcgaatga cagggataga
    30181 caaggttttt ctggctcttt ttattgtctg ggcgactgat attggagctt acttgattgg
    30241 gcgccgattt ggtaagcgaa agctcctgcc aaaaatatca cccaacaaaa caattgaggg
    30301 cagccttggt ggtatagtca gtgcggtgct tgtttccttt gtgtttatgc tctttgataa
    30361 ggctgtttat gctcctcatc attttggaac aatgttgatt ttggtggctc ttttttctat
    30421 ttttgctcag tttggagatt tggttgaaag tgctgtcaaa agacatttcg gagttaagga
    30481 ctcaggcaaa ttgattccag gccatggtgg tattttagat cgttttgatt cgatgatctt
    30541 tgtttttccc attatgcatc tatttgggtt attttaaagc tcattatcaa tagactgaaa
    30601 ggaaatctat gttaggaata attaccttta ttattatttt tggtattctt gtgcttgtcc
    30661 atgagtttgg ccatttctat tttgctaaac gatctggtat tttagtcaga gagtttgcta
    30721 ttggcatggg accaaaactc ttttcgcatg ttgatcagca aggaacgctt tacacgatcc
    30781 ggctattacc gcttggtggc tatgtgcgaa tggcaggctg gggtgatgac acaactgaga
    30841 taaaaacagg aacgcctgct agcttaacgc ttaatgatca gggcttggtc aagcggatta
    30901 acctgtctca gagcaagctt gatccgacta gcctgcctat gaatgtgact gcttatgact
    30961 tagaagataa gttgacgatt acagggctgg ttcttgatga gatcaagacc tattcggtag
    31021 accatgacgc gaccattgtc gaggaggacg gtacagagat ccggattgcg ccgcttgatg
    31081 ttcagtatca aaacgcaagc attggcggtc gtttgatcac caattttgca ggacctatga
    31141 ataattttat tctaggtatt gttgtcttta ttttgtttgc ctttgttcaa ggtggtgtgg
    31201 ctgattatca tagcaaccat attcgtgtgg tggaaaatgg cgcagcagcc aaggctggta
    31261 ttagagacaa tgatcagatt ttagagatta atcatcaaaa gattaatgac tggtatgagt
    31321 tgacgcaggc cgttactgat tcagcagcag atgttaaggc taagggcaag ctagagatta
    31381 cctatcagac aggtgatcag gttaagacta tagcactgaa gcctgaaaaa aaaggcgatc
    31441 agtaccttat tggtgtccag tacccactaa aaacaagtct gacagacaag ctaataggtg
    31501 gctttgagat ggctggtaat ggtgctctag tgattgtcac tgctctaaag agtttgatta
    31561 cctcctttag cctagataaa ttaggtgggc cagttgccat gtatcagatg tccaatcagg
    31621 cagcaaagaa tggtttagag tctgtcttgt ccttgatggc aatgctctct atcaatttag
    31681 ggatttttaa tttgattccg attcccgcac tagatggtgg taagatcctg atgaatgtga
    31741 ttgaagcact tcgtcgtaag ccattaaagc aagagacaga gacttatatt acccttgcag
    31801 gtgttgcgat tatggtggta ctcatgattg cagtgacctg gaacgatatt atgcgagcct
    31861 ttttccaagg ctgatggtct ctctcattta aaggagagcc taaaaggctt aatgtaacag
    31921 aaataacaag agatatagtg tcattattgt ggttctaaga ccttgcaaat gcagcaaaag
    31981 cttagccaat atagctcatt ttgtctcttt tttagaaatg aattctcaac gaaaggaaag
    32041 agagctgttg accaagctgg gctaaggcct acagctgaaa tcaaaatgct agacctgcta
    32101 ttagtctaag ggcgttttga gctgctctct atagcttatt ttaatgaaac aaagtaaaat
    32161 gcttatccca accctgcgcg aaatgccaag tgacgctcag gtaatcagtc atgccctcat
    32221 ggtgcgtgcg ggctatgtcc gtcaggtatc tgccggtatt tatgcctatt tgccattagc
    32281 tcatcgtaca attgaaaaat tcaagacgat tatgcggcag gaatttgaca aaattggtgc
    32341 tgttgaaatg ctagcacctg cccttttaac agctgacctc tggcgtgaat caggccgcta
    32401 tgagacttac ggtgaggacc tttacaagct aaaaaaccgc gacaaatcag actttatctt
    32461 aggtcctacc catgaagaaa cctttactac actggtgcgt gatgcggtta aatcctataa
    32521 gcagctgccg ctcaatctgt atcagattca atccaaatat cgtgatgaaa agcgtcctcg
    32581 taatggcctg cttcgcacac gtgaatttat catgaaggac ggctatagct ttcatcaaag
    32641 ctatgatgat ttagatgtca cctatgacgc ctatcgtcag gcctatgagg ctatttttac
    32701 cagagcaggc ttggatttca aaggaattat cggtgatggt ggtgctatgg gtggtaagga
    32761 ttcgcaggaa tttatggcta tcacaccgga ccgtactaat ttagaccgct ggctggtctt
    32821 agacaagtct attccgtcat tggctgacat tccagaggag gtcttggaag agattaaggc
    32881 cgagctggct tcatggctgg tttcaggaga ggacaccatt gcttattcaa gtgaatcaag
    32941 ctatgctgct aaccttgaga tggcaaccag tgagtacaag tcctcatcaa aggtaacagc
    33001 cttagatgat ctcgtcgaga ttgagacacc aaattgtaaa accattgatg aagtggcggc
    33061 ctttcttgac gttgctgagc atcaggtcat taaaaccctg ctctttatgg tggaccatga
    33121 gcctgtgctt gctttattgg ttggaaatga ccagatcaat gctgtcaaat tgaaaaacca
    33181 cctcggtgca gacttcttag agccagctag cgaggaggag gcgcgtgcta tcctaggtgc
    33241 aggctttggt tcacttggtc cagttcattt gacagatggt atccgtattg tggctgatcg
    33301 taaggtccaa gaccttgcta atgctgtagc tggagccaat aaagatggtt atcacctgac
    33361 tggtgtcaat ccaaatcgtg atttccaagc agagtatgct gatattcgtg aggtaaaaga
    33421 gggagagacc tctccagata gacatggcgt gctgcagttt gccagaggta ttgaaatcgg
    33481 tcatatcttt aagctgggga cccgctattc tgatagcatg gcagctaata tccttgatga
    33541 gaatggcaga gcagttccga ttgtcatggg ctgctatggt attggggtta gtcgtatcct
    33601 atcagcagtc attgagcagc atgctcgtct ctttgtcagc aagacaccaa agggtgatta
    33661 tcgctatgct tgggggatta atttccctaa agagctagct ccgtttgatg tgcatttgat
    33721 taccgttaat gtcaaggatc aggaggcgca ggacctgaca gaaagagtag aggctagtct
    33781 gatggccaag ggctatgatg tcctcactga tgaccgcaat gagcgtgtcg gctctaagtt
    33841 ctctgatagt gatttgattg ggcttccgat tcgtgtgacg attggtaaaa aagcagctga
    33901 gggcattgtt gagatcaaaa tcaaagcaac aggtgacagc attgaggtgc acgctgatag
    33961 cttgattgaa actcttgaca ttctcacaaa ggacaactaa tgatatgagg tcaacgatgg
    34021 ttgatctctt tttgtatgct ataatgaaag catgacaatt gaggaattac agcagctggt
    34081 gctagcagat catgagctaa tgactattct aagcattata gagaccttgc ctttaaagga
    34141 ttgttggctg gcagcaggtg caattcggaa cgctatttgg aatcatttag cttatgggat
    34201 aggctttgat ccgctgacag atgtagatgt ggtctttttt gaccctgaga tctcttacga
    34261 agctgagcag ctgctagaag agcagcttaa gtgtgcttat cccatgtacc aatgggaggt
    34321 tcgcaatcaa gcctatatgg cagcacataa ccccaagacg cctccttatc gatctagtca
    34381 agacgctatc acaaagtatc cggagcgctg tacagcgatt gctgttagac ttgtaggagg
    34441 acagctagag gtttttgctc cctatggttt agcagacatt agtcactttg tctgtcggcc
    34501 aacaccgcat tttttagagg attcagagcg tatggactgc tataggcagc gcctagcaaa
    34561 gaaggactgg cacaagaaat ggccacagct gacctaccac gactgctaag tcagaggaaa
    34621 caaagcaggc taggagctcc gtacagccaa gcaattagtc cgctcccaga cccgttagct
    34681 acagctctca cctagtcaaa acaagcacat gaacagatca ttggcagata gccttgcctt
    34741 tgcagatatt gtcacaccct atttagctgt accatgtgtc ttatgatagg cgtgatagtg
    34801 ctgtcagaag cgccagctga gccagaaaaa gcgttaagcc tacagcaagg ggcttttaac
    34861 ctttggtatg ttgtcttgta ggagaggtcg aaaatgatca ctatttatga taaaatagac
    34921 cctaagaaaa tcaggagaaa gctatgtcag atttattcgg taaattgatg gaacaaattg
    34981 aaatgccact tgagataaga caatcaagtg ccttttcgtc tgctgatatt atcgaggtca
    35041 aggtgcattc agtgtctcgt ctgtgggaat ttcatttttc ctttgcagag gttctcccga
    35101 tagagagcta tcgagagctg tcagataggc ttgtgagaac ctttgaggca gcagatatta
    35161 aggtaacatt tgacatcaag gcagagacaa ttaattattc ggatcagctg ctgcaagcct
    35221 actatcaaga agcatttgag catgagccct gtaatggggc tagcttcaag tcatcttttt
    35281 ctagacttca ggtcaggtat gaccatcatc agctgatcat tatggcacct gactttgtga
    35341 ataatgatca ctttaggaaa aatcatttac ccaatctggc agctcagttt gagcgctttg
    35401 gctttgggag gctagcgatt gatatggtgt ctgatcagga gatgacagac catttgacaa
    35461 aggactttga gaccaaccgt caggctctgg tggaaaaggc tgtacaggat aatatcgcag
    35521 cacagcaatc attggaggcc atgcagccac cagctgagga ggcagcacca agcccaagcc
    35581 ttgactatag agagcgtatg gctcagcgcc aagcaagctt tgataaggcg gtcattacac
    35641 caatgattga ggtggataca gaagaaaatc gcattgtttt tgaaggaatg gtctttgatg
    35701 tggagcgcaa gacgacaaga acaggccgcc atatcatcaa cttcaagatg acagattaca
    35761 cctcctcctt tgccatgcaa aaatgggcca aagatgacga tgagctcaga aaatttgatc
    35821 tgattgcgaa gggagcttgg ctgcgcgttc agggaaatat cgaaaacaac cccttcacca
    35881 agagcctaac catgaatgtg cagcaggtta aggcgattgt tcaccatgag cgtaaggatc
    35941 tcatgccaga agggcaaaag cgtgttgaat ttcatgcaca cactaatatg tccacaatgg
    36001 acgctctacc gacggtagaa gacctgattg atacagcagc caggtgggga catcaggcag
    36061 tagcgattac tgaccacgct aatgttcaga gctttccgca tggctatcat agagcacgca
    36121 aggcaggaat caaggcaatc tttggcttag aggccaatat tgttgaggat aaggtaccta
    36181 tttccttcaa tcctgtcgct atggacctgc atgaagccac ctatgttgtc tttgacgtgg
    36241 agaccaccgg cctttctgcc atgaacaatg atttgattca gatcgcagct tccaaaatgt
    36301 tcaagggaaa tatcattgag cagtttgatg agtttatcaa tccaggccac cccttatctg
    36361 cttttacaac agaattgaca gggattacag ataatcattt ggtaggagct aagcctatac
    36421 agcaggtgtt agaggcattt caggcctttt gtcagggcac tatcctagtt gcccacaatg
    36481 ctagctttga cgtgggattt atgaatgcca actacgatcg gtatggttta gcaaaaatca
    36541 gccagccagt tattgacacc ctggagcttg ccagaaacct gtaccctgag tataagcggc
    36601 atggcttggg ccctttgact aagcgctttc aggttagcct tgagcaccat cacatggcca
    36661 attacgatgc tgaagcaaca gggcgtttgc tctttatctt cctaaaggaa gctagagaaa
    36721 agcatgggat tacaaacctg cttcagctca atacagactt agtggcagag gattcctata
    36781 agaaagcacg gatcaagcac gccacgatct atgttcaaaa tcagctaggt ctcaaaaaca
    36841 tgtttaagct ggttagcctt tcaaatgtga aatattttga aggtgtgcct agaattccaa
    36901 gaaccgtcct tgatcagcat cgtgaaggct tgctgcttgg gacagcctgc tcagacggcg
    36961 aggtctttga cgctgttttg acccaaggaa ttgacgctgc tgttgatctg gccaaatact
    37021 acgattttat cgaaatcatg ccgcctgcaa tttaccagcc cttggtagtc cgagagctaa
    37081 tcaaggatca agcaggagtt gagcagatta ttcgcgattt gattgaggtc ggccgcagag
    37141 ctgaaaagcc tgtcctagct actggaaacg tgcactacat tgagccagag gacgccatct
    37201 atcgtgacat tatcgttcgt agtctagggc aaggtgccct gattaaccgt actattggcc
    37261 gcggagaggc tgccaagcct gtcccgctac cagaggctca ttttagaaca accaatgaaa
    37321 tgcttgatga ttttgccttt ttaggtcagg acttggccta tgaggttgtg gtgcaaaata
    37381 cccaagccct tgctgatcga attgaaaagg tggaggttgt taaggatgat ctgtacaccc
    37441 catatattga taaggcagaa gaaaccgttg ctgagctgac ttatcaaaag gcctttgcta
    37501 tctatggcaa cccacttcca gatatcattg atctgcgcat tgaaaaggag ctaacgtcca
    37561 ttttgggaaa cggctttgcg gtgatttatc tagcctcaca aatgctggtt aatcgctcta
    37621 atgagcgtgg ttatctggta ggctcacgtg gctctgttgg ttcaagcttt gttgcgacca
    37681 tgattggcat cacagaggtc aatccaatgc cgcctcatta tgtctgccca agctgccagc
    37741 agtcagagtt tatcacagat ggctcggtcg gctctggcta tgatttgcca aacaaggcct
    37801 gtcctagatg tgggacgctg tacaaaaagg acggacagga tattcctttt gaaaccttcc
    37861 ttggctttga tggtgataag gttccagata ttgatttgaa cttctcagga gatgatcagc
    37921 ccaatgccca cttggacgtt cgtgatatct tcggggaaga atacgccttt cgtgcaggta
    37981 ctgttggtac tgtcgctgaa aaaacagcct atggctttgt caagggctat gagagagatt
    38041 atggcaagtt ttacccagat gcagaggttg atcgtctagc tgctggtgct gctggtgtta
    38101 agcggacgac tggtcagcac cctggtggga tcgttgttat ccctaactat atggacgttt
    38161 atgattttac acctgtgcag tttccggcag atgatgtgac agcctcatgg cagacgaccc
    38221 actttaattt ccatgatatt gatgaaaatg tcctaaagct cgatgtactc ggtcatgatg
    38281 atcccaccat gattcgtaag ctgcaggatt tatcaggtat tgatccgatt actattccag
    38341 cagatgatcc tgacgtgatg gcactttttt ctggaacaga ggtgctcgga gtgactcctg
    38401 aacaaattgg aacaccaaca ggtatgcttg ggatcccaga gtttggaacg aactttgttc
    38461 gtggcatggt gaatgagacc cacccaacga cctttgcaga attgctgcag ctatcaggtc
    38521 tatcgcatgg aacggacgtc tggctgggta atgctcagga tctgatcaaa gaaggcattg
    38581 ccaccctaaa aacagttatc ggttgtcgag atgacatcat ggtttacctt atgcatgctg
    38641 gtctagagcc taagatggcc tttaccatca tggagcgtgt gcgtaagggg ctctggctaa
    38701 agatttccga ggaggagcgc agctcctata tcaaggccat gcggcaaaac aacgtcccag
    38761 actggtacat cgaatcctgt ggtaaaatca agtacatgtt ccccaaggct cacgctgccg
    38821 cctatgtttt gatggcattg cgagtggctt atttcaaggt tcatcacccc atcatgtatt
    38881 actgtgctta tttctctatt cgtgccaagg cctttgagct caaaaccatg agtggtgggc
    38941 tagctgctgt caaggctcgc atggaggaca tcagcaacaa gcgcaagcgc aatgaagcct
    39001 caaacgttga aaatgacctg tttaccactt tagaaattgt caatgaaatg cttgagagag
    39061 ggtttaagtt tggcaagcta gacctttaca agagcgaggc aactgagttt caaattgaag
    39121 gggataccct aattccacct tttattgcct tagaaggctt gggagaaaac gttgctagac
    39181 aaatcgtcaa ggctcgccaa gatggtgaat ttctatcaaa aatggaatta cgcaagcgtg
    39241 gtggtgcttc tgccactcta gttgataaga tggacgagct gggcatttta ggaaatatgc
    39301 cagatgacaa tcagctgagt ctatttgatg actttttcta agattgcaca gccctaatat
    39361 tgtctatgtt agcttgtcat acagtgaaga gcagggcagg aaggcttcct gtcctctttt
    39421 tgtcaatacg caaagaaagc ccaaaaaaga acgaggaaaa gcatgaatga attagacaaa
    39481 aatcctgcct taaaggcaat ggttgttttt agaaaagcac agcgtacctt agatgctcaa
    39541 agctccgcct tttttcaaaa ggccaatctg actcctaccc aatttagcgt cttagaggtg
    39601 ctttattcca aaggaagcat gagaattaac aagctcatcg gttctctctt ggcaacctct
    39661 ggcaatatga ccgtagtgct gaaaaatatg gagagaaatg gctggatcag ccgctgccaa
    39721 gatgctaaag ataagcgtgc ctgcttggta cagctaacgc cagagggcaa agccttgatt
    39781 gagactatcc tacctgagca tatcaaacgt gttgaagccc ttttttcagt gctgacagag
    39841 actgagcaaa aacaattgat tacgctttta aagaaattta aagaactcta agcaaatggc
    39901 tttacaggat ctcccaagta ggatataatc actacatagt acaaaaagat actaactagt
    39961 cataataagt catcaagaca gcagatggct agttaccaga taatcaatgg gagacaaagc
    40021 atgaaacaaa ttttaatcat taatggttca ttacggacag gttcatttaa tcatcagctt
    40081 gctcaagcgg ctgagcagct acttgaaggc aaggcagctg tatcttactt ggactgggaa
    40141 caggtaccta tgtttagtca ggatttagaa gcaagcaccc ctgagtcagt ggcaggcgta
    40201 cgagaagcca ttcaagcagc agatgctatc tggatttttt cacctgtcta taattttgca
    40261 atcccgggct ctatcaaaaa cctattagac tgggtatcac gcgcccttga tttgtcagac
    40321 ccatcaggac catcagcaat caatggtaag gtagttaccg tatcatctgt tgctaatggt
    40381 gggcacgagc agctatttgc gcaataccag gacctgctgc cctttatccg tacgacagta
    40441 gttggtaact ttaccaaagc cgctgtcaat ccagaagcat gggcgacagg tgttcttgat
    40501 atttctgagg aaacaaggca aagccttgca gcacaggcag aagcccttct tgaagccatt
    40561 cactaagact ctctgagcat taaacagata aagctgcagc taggatcaaa aagcagctag
    40621 acacataaaa agagcttaaa ccagaaatgt acggcactcc aaaagctaga caaaaactct
    40681 agcgattggg gtacaggtca aaacggtttt aagctctttt ttagacttat tttatagtag
    40741 taacttaatt aagaattagc ataccctctt tagcctcaaa ggggtttttc gcattaatac
    40801 ggtcatagaa taagacacca ttaatatgat caatctcatg ctgaaccacg atagcattgt
    40861 agccctttag cttaatgcgg tgcttttcat tgtgcttatc gtaatattcc actgtcacac
    40921 gcgcatgacg gacgacatag ccttccacca cacgatcaac agacaaacac ccctcaccgt
    40981 cagcaagagc agcgtcttga acagaatgag acacaatttt aggattatag agcacttcct
    41041 ccatgctgta agcctcctta ggtggattgc cctcgctgtc ttcaggattt ggaaccagaa
    41101 cagcgatgat acgctttgac acatcaatct gaggtgctgc tagaccaact cctgctcgaa
    41161 gccctaattt ttctcccatg acagggtctt gagaatgctt taaaaattgc atcatttttt
    41221 cacctaaaat gatgtcatca tcactaagag gaaactcgac ctccttagcc acagcacgaa
    41281 gcgtaggatt gccttcgcgg ataatatcat tcatatcaat gagatgctgt gctttaatta
    41341 atttatcttg tgcagacatt ttgcctccct ttttttatat ttgataatgg ctttactata
    41401 tcacaaaatc cttattttta aaagataagg caggccagtg atgacgatat tagctaactc
    41461 tatcagatat attaaattat ttaaaaaata gttcgttaat tagcacgaca tatatataag
    41521 aaatacacag gaattctaat aattaataga taaaaaatga taatcgttcg taaataaatc
    41581 aaacatctaa tctaaaaaaa ttatattgtt ctgattgttc ggtaattaaa gcaatagcgc
    41641 ttgtcgaaaa actaatgttc tcttaatatc aggtagccat gccaagggtt ttgtgttaaa
    41701 gtataggacg ttcaaaaaat gaaatggaga gactaatgag aacacaattg aaaaaattgc
    41761 tggcaggaac agcagcaggt accctgctgc tgtttaacct gacctgcgga atgattaatg
    41821 cttttgcaga gcagtattac gggtggagtg acgggagtag cagctatccg agtgctttgt
    41881 atgttacacc ggtaggagat actacgaaaa agatagctat tcctgtttat tgctttgact
    41941 ataagtttca ggagccactt gcttggaaag aaataactca accgtcacac ttgattgtct
    42001 atgataagta tgatggcaaa aatttgatgg cagcactggt tgaaaaacct aatatggtaa
    42061 gctatgagac taaaactaaa cttcaaacac ttttaaagac aaagtcaaat ctaataactg
    42121 caattttaag tagaggttat ccaaacaaaa gtttttttga taagtataaa aaattaactg
    42181 atgaagataa aagacgagtg acacaatgtg ctctttggta tcatactgac aatatttcag
    42241 aacaagatct tatcacaaaa catttggatg gggattcagg tgaaaaaagt caagcgctaa
    42301 aggagttaat aggggttgta aaaaatactt ctaatgagtt aggagaggga ttaaccttct
    42361 atactcgtta taatgataga tatggtccta aatatcaaaa cctaataggc tcaattattg
    42421 ttcccgaaga gcctcagaat gatcttgaaa ttggtggtgg aaatgttatt gatttaaact
    42481 accaatctgg accaatggta gaagaaggtg gtcattcagg tggcaaggaa gaggtcgagg
    42541 acactaaaaa gcctgatgtg attattggtg gtcagggaag cgttactgag actactgagg
    42601 atactcaaaa gggtatgagt ggcagtactg agactcagcc agaggttgag gatactaagc
    42661 agccacaatc agatattatc ctaggcggac aaggcaatgt gattgacaca actgaaaata
    42721 cccaagaggg catgggtggc caatcaggtg atactacaga gactgaggat accaagcagc
    42781 cacaatcaga cattatccta ggtggacagg gcaatgtaat tgacaccact gaaaatactc
    42841 aagagggtat gagtggttcc aacaatggtc aaacatttga ggaggacaca cgtcctaagc
    42901 tggaattcca ttttgataat gaagtgccta acgatgatga cgctcctaaa ccagagcaac
    42961 cagaacagcc agagaagccg gagcaaccaa ggaagccaca gcaggagcag caaagcctac
    43021 cacgtccaat agagggcaac cagtcattgc caaaaacaca tgaggcaaaa ggtgtactgg
    43081 ctctagtagg agtaggaatc cttgctatgc taggactagg cttttggttt agaccttatc
    43141 aaaaagacta aatcaaggct cagcagctat ttaagctaaa cagctgtgct cagctaaatg
    43201 ataaaacaat taagattgga gaatgtggct attagtagct tctccaatct tttttgatag
    43261 cagcatgtgc tttttctgcc gtattttatt gagaataata gttgaccagt ctaggcgatt
    43321 ttgctagaat agagaggtcg caagacagac taactttttc ttggttttag gagtgccaac
    43381 cctaaaactc ggattaagca aaaaaggaga attattatgg caatctcaaa agagaaaaaa
    43441 aatgaaatta ttgcacaata tgcacgtcac gaaggtgaca caggctcagt tgaggttcag
    43501 gtagctgtcc ttacttggga aatcaaccac ttgaacaacc acatcaagga gcacaaaaaa
    43561 gaccacgcaa cttatcgtgg attgatgaaa aaaatcggac accgtcgtaa cctattagca
    43621 tacctacgtc gtacagatgt taaccgttac cgcgagttaa tccaatcact tggacttcgt
    43681 cgttaattgg cttgacagag gtcattttag agataaccaa gttctattga aaaaagatct
    43741 gctagtgtac tgacccccaa aagttggaca cgacatatta gtgaaaggat ttagttctgt
    43801 attgcacagg gctaagtcct tttagctttg ctttaatgcg tttgttgttg tagtaaaaaa
    43861 tgtaatctgt aatagcttgt tcaagctcat taagggattg ataagttgtc tcaaggccgt
    43921 aaaacatctc agatttgaaa ataccaaaga aggactccat catcccatta tctggactat
    43981 ttcccttgcg agacatggat ggacgaatgc ctttagtctc caaaaagtga tgataagact
    44041 gatgttgata ttgcca
//
LOCUS       DARYLD010000010        42417 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYLD010000010 DARYLD010000000
VERSION     DARYLD010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42417
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            372..854
                     /gene="rimP"
                     /locus_tag="TU651_000462"
     CDS             372..854
                     /gene="rimP"
                     /locus_tag="TU651_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL0896493.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
     gene            964..2118
                     /gene="nusA"
                     /locus_tag="TU651_000463"
     CDS             964..2118
                     /gene="nusA"
                     /locus_tag="TU651_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL0896494.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            2134..2430
                     /locus_tag="TU651_000464"
     CDS             2134..2430
                     /locus_tag="TU651_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL0896495.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            2423..2725
                     /locus_tag="TU651_000465"
     CDS             2423..2725
                     /locus_tag="TU651_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL0896496.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            2745..5615
                     /gene="infB"
                     /locus_tag="TU651_000466"
     CDS             2745..5615
                     /gene="infB"
                     /locus_tag="TU651_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL0896497.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            5805..6155
                     /gene="rbfA"
                     /locus_tag="TU651_000467"
     CDS             5805..6155
                     /gene="rbfA"
                     /locus_tag="TU651_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL0896498.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(6227..7264)
                     /locus_tag="TU651_000468"
     CDS             complement(6227..7264)
                     /locus_tag="TU651_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0896499.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            7494..7928
                     /locus_tag="TU651_000469"
     CDS             7494..7928
                     /locus_tag="TU651_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL0896500.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            7928..10159
                     /locus_tag="TU651_000470"
     CDS             7928..10159
                     /locus_tag="TU651_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL0896501.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            11030..11980
                     /locus_tag="TU651_000471"
     CDS             11030..11980
                     /locus_tag="TU651_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL0896502.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            11993..12544
                     /locus_tag="TU651_000472"
     CDS             11993..12544
                     /locus_tag="TU651_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0896503.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(12960..13742)
                     /locus_tag="TU651_000473"
     CDS             complement(12960..13742)
                     /locus_tag="TU651_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0896504.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            13878..14303
                     /gene="lacA"
                     /locus_tag="TU651_000474"
     CDS             13878..14303
                     /gene="lacA"
                     /locus_tag="TU651_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL0896505.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            14319..14834
                     /gene="lacB"
                     /locus_tag="TU651_000475"
     CDS             14319..14834
                     /gene="lacB"
                     /locus_tag="TU651_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL0896506.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            14844..15776
                     /locus_tag="TU651_000476"
     CDS             14844..15776
                     /locus_tag="TU651_000476"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL0896507.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            15778..16044
                     /locus_tag="TU651_000477"
                     /pseudo
     CDS             15778..16044
                     /locus_tag="TU651_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            16047..16532
                     /locus_tag="TU651_000478"
                     /pseudo
     CDS             16047..16532
                     /locus_tag="TU651_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            16743..17615
                     /locus_tag="TU651_000479"
     CDS             16743..17615
                     /locus_tag="TU651_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL0896508.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            17776..18390
                     /locus_tag="TU651_000480"
     CDS             17776..18390
                     /locus_tag="TU651_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL0896509.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            18395..19219
                     /locus_tag="TU651_000481"
     CDS             18395..19219
                     /locus_tag="TU651_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0896510.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(19630..20187)
                     /locus_tag="TU651_000482"
     CDS             complement(19630..20187)
                     /locus_tag="TU651_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0896511.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            20319..21161
                     /locus_tag="TU651_000483"
     CDS             20319..21161
                     /locus_tag="TU651_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0896512.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            complement(21767..22513)
                     /locus_tag="TU651_000484"
     CDS             complement(21767..22513)
                     /locus_tag="TU651_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896513.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            22704..24345
                     /locus_tag="TU651_000485"
                     /pseudo
     CDS             22704..24345
                     /locus_tag="TU651_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            24462..25610
                     /gene="nagA"
                     /locus_tag="TU651_000486"
     CDS             24462..25610
                     /gene="nagA"
                     /locus_tag="TU651_000486"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL0896514.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            25697..26536
                     /locus_tag="TU651_000487"
     CDS             25697..26536
                     /locus_tag="TU651_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL0896515.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            26566..26790
                     /locus_tag="TU651_000488"
                     /pseudo
     CDS             26566..26790
                     /locus_tag="TU651_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            27057..27590
                     /locus_tag="TU651_000489"
     CDS             27057..27590
                     /locus_tag="TU651_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL0896516.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            27956..28867
                     /gene="glyQ"
                     /locus_tag="TU651_000490"
     CDS             27956..28867
                     /gene="glyQ"
                     /locus_tag="TU651_000490"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL0896517.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            29233..31272
                     /locus_tag="TU651_000491"
     CDS             29233..31272
                     /locus_tag="TU651_000491"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL0896518.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            31809..32066
                     /locus_tag="TU651_000492"
     CDS             31809..32066
                     /locus_tag="TU651_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL0896519.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            32595..32759
                     /locus_tag="TU651_000493"
     CDS             32595..32759
                     /locus_tag="TU651_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL0896520.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            32987..33937
                     /locus_tag="TU651_000494"
     CDS             32987..33937
                     /locus_tag="TU651_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL0896521.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            33934..34998
                     /locus_tag="TU651_000495"
     CDS             33934..34998
                     /locus_tag="TU651_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL0896522.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            35011..36369
                     /locus_tag="TU651_000496"
     CDS             35011..36369
                     /locus_tag="TU651_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL0896523.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            36344..37015
                     /locus_tag="TU651_000497"
     CDS             36344..37015
                     /locus_tag="TU651_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0896524.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            37012..37698
                     /locus_tag="TU651_000498"
     CDS             37012..37698
                     /locus_tag="TU651_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL0896525.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            37721..38644
                     /locus_tag="TU651_000499"
     CDS             37721..38644
                     /locus_tag="TU651_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896526.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            38653..39780
                     /locus_tag="TU651_000500"
     CDS             38653..39780
                     /locus_tag="TU651_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896527.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            39777..40895
                     /locus_tag="TU651_000501"
     CDS             39777..40895
                     /locus_tag="TU651_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896528.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(41028..42353)
                     /locus_tag="TU651_000502"
     CDS             complement(41028..42353)
                     /locus_tag="TU651_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0896529.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPDPQPKPEPKPQPEPKPEPKPQPEPKPEPKPQPVPKPDP
                     EPMPDPEPKPQPEPKPEPQPEPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQK
                     PTKPSNTTSQSSGKGLPRTNEAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
BASE COUNT        11809 a         8100 c        10153 g        12355 t
ORIGIN      
        1 tctctcgcat atgcatagat ctgttctgat gggaggtttt ttcgttttgg taaagaccat
       61 gaagcagccg caaataatat tttagttgtc ttttttaccc tttaatattt tattttatca
      121 tatgaataca gaggttagag gggataagga aagagaaaaa agcaaggtta aagatctcct
      181 ctccttttaa aaaataggat ttttgaggtc ttattgacac ttttagtagg gattttcttg
      241 caattcattt tgattgtggt ataataggtt aaagcaatac agaagggtgg tgagaaatat
      301 ctcgccactt ttgtgttgat tatcaagagg acaaggctat agaggtatag cagtcatcag
      361 taaaggaggt tattaacatc gcaaacacag ctattattga tattgttacc caaatcgtag
      421 aacctgtaat taaagcaccc tatgaattgg tcgacatcga atacgacaaa atgggcaatg
      481 attatgtcct tagtatctta gttgataagg cttctgggat taccgttgag gatactgctg
      541 agcttacaga gttaatcagt ccactcttag atacgatttc tccagaccct ttcccagatc
      601 agtatatgct ggaggtttcc agtcctgggc tagagcgtcc attaaagact gctgagagct
      661 tgaaggctgc tgtaggctca tatattaatg tcagcctcta tcgggcaatt gataaggtga
      721 aggtttttca aggagattta gtggcttttg atggtgatac cctaaccatt gattatctag
      781 ataagacgcg tcacaaaaca gttgagattc cttaccaagc agtggctaag gctcgtttag
      841 ctgtcaaatt ataaggcaat tgctgagcga tttgctttag tcggttggct aagccctaaa
      901 tggattaatt tataagataa gaaaggattt ttaccaagct ttgagagcaa ggtagacaac
      961 attatgagca aagaaatgct agaagccttc cgtattttgg aagaagaaaa acacattgat
     1021 aaggcagata tcattgaggc agtcactgaa tcactgaaat cagcttataa acgtcgttat
     1081 ggtcaagcag aatcctgcgt cattgaattt aatgataaaa cagcagattt tcaggttttt
     1141 acggttcgtg aggttgttga agaggtattt gatagccgtc tggaaattag cctgaacgat
     1201 gcccttgcca ttagctcagc ctatgagtta ggagataaga ttcgttttga agaatcagtc
     1261 agcgagtttg gacgtgtggc tgctcagtct gcaaagcaaa ccattatgga aaggatgcgt
     1321 cgtcagatgc gagaaatcac cttcaatgag tacaagcagc atgaaggtga aatcatgacg
     1381 ggtacggttg agcgttttga ccaacgtttc atttatgtta accttggttc cttagaggct
     1441 cagctctcac atcaggatca aatcccagga gaaaccttca aatcacatga tcggattgat
     1501 gtctatgtct acaaggtgga aaacaatcca aagggggtta acgtctttgt tagtcgtagt
     1561 caccctgagt tcatcaagcg cattatggaa caggaaattc cagaggtttt tgatgggacc
     1621 gttgagatta tgagtgtttc tcgtgaggct ggtgaccgta ctaaggttgc tgtgcgtagc
     1681 cacaatccca atgttgatgc gattggaacg attgttggtc gtggcggcag caacatcaaa
     1741 aaggttatca gtaaattcca tccaaagcgc tatgatgcta agacaggact tgagatccca
     1801 gtagaagaaa atattgacgt tatccaatgg gtagatgacc ctgctgaatt tatctacaat
     1861 gccattgcac ctgctgaggt tgatatggtt ctctttgatg atgacgatct taagcgtgcg
     1921 actgtggtgg tgcctgataa taagctatcg cttgctattg gtcgtcgtgg tcaaaacgtt
     1981 cgtttggcag ctcatttgac aggctatcgc attgacatca aatcagccag tgaatatgaa
     2041 cgccttgaag cagaaaaaga agcagcaatg actgaagcag tagctacaga ggagctctta
     2101 accaacgagg aagtgtaaga aaagaggtgt tttatgccta aagtaaaaaa aataccttta
     2161 cgtaagtcgc ttgtttctgg tgagatcatt gataagcgtg acctccttcg tattgtcaaa
     2221 aataaggagg ggcagatttt tattgatcca accggcaagc aaaatgggcg tggtgcttat
     2281 atcaagctag ataaccaaga agcacttatg gcaaagaaaa aacaggtgtt taatcgtagc
     2341 ttctcaatgg aggtgccaga gagcttttac gatgaagtga ttgcacatgt tgatcacaaa
     2401 gttaaaagaa gagagctagg ccttgaatag tttaaataga ttatctcatt tgatcggact
     2461 ggctcagcgg gccaaaaaag tgatttcagg tgaggaattg gtcattaaag ccattcgaca
     2521 tcaggaagtc aatcttgttt ttttagccaa tgatgctggc ccaaatatca ctaaaaaagt
     2581 aacagataaa agtaattatt acaatgtaga agtctccaca gtgtttagtg cactggaatt
     2641 aagtgctgca cttggcaagc ctcgtaaggt ggttgccatt gcagacgctg gattttcaaa
     2701 gaaaatgagg actcttatga aatagacgaa taggaggaca caaattgtca aagaaaagat
     2761 tacatgaaat tgccaaggaa attggcaaaa gtagtaaaga agtcgttgag cgtgctaaat
     2821 ccttaggatt agatgtcaaa agccatgcgt caagcgtcga agaagcagat gctaacaaaa
     2881 ttgcctctag cttttcagca ggtgtgacta agaatgttca agcaggttca gcaaaagaca
     2941 agcaagtagc agaacaaaaa gcaaaagcag ctaaggccac tacaccacag ccagcagcct
     3001 ctaaagcagc agaaaagcca gctgctgcga cacaagaagc atcacagccg gttgctgtta
     3061 agccaaagag ccgcaatttc aaggcagagc gtgaagcacg tgccaaggag caggtagcga
     3121 gacggcaggc tgggcaaaat cgctctaatg accgcaagtc agactatcgt caacttggac
     3181 gatcacaagg tcagcagacg gagcgagctg gccacaagtc acaaaatcag caaagagata
     3241 gacgctttga taacaggcca tcatctggaa ataaccgaaa cgatgggcat agacaagctg
     3301 gtaatcgtga caaaaaccgt tcctttaacg ctaatagtcg tcaacaggat acaggacgtc
     3361 aagggcagac ccaagccggt gctcctaaga ttgattttaa ggcgcgtgct gctgccttaa
     3421 aggctgagca aaacgcagag tatgccagac aaagggaatc acgctttcgt gagcaagagg
     3481 aggctaaacg cttagagcaa caggcaaggc aagaggctaa ggcagccgcc ctcaaggctc
     3541 agacagagga caaaaagcat cgtgaagcct cagctaaggc tactgagtcg gttgctagta
     3601 tggctgctgc atcggtagca aaaccggttg ataagcgtcg taaaaaacaa aatcgtccag
     3661 acaaagggca tgatcgggat catggcctag aagatggaca aaagaaaaat aagaagagtt
     3721 ggaatagtca aaaccaagtg agaaatcaaa agaatagtaa ctggaataac aacaagaaaa
     3781 acaaaaaagg taagcatcat aagaatagca acacagctcc aaaaccagta acagagcgta
     3841 aattccatga attaccaaaa gaatttgaat attcagaagg aatgaccgtt gctgaaattg
     3901 caaaacggat caagcgtgag ccggctgaga ttgtcaagaa attatttatg atgggtgtga
     3961 tggcaacgca aaaccaatcc ttagatggtg ataccattga gctcttaatg gtggattatg
     4021 gcattgaagc taaggccaag gtggaggttg atgaagctga tatcgagcgc ttctttactg
     4081 atgatagcta ccttaatcct gagaatattg ttgagcgtgc accggttgtt accattatgg
     4141 gacacgtcga tcatggtaag acgaccctgc ttgataccct tagaaattct cgtgttgcaa
     4201 caggagaagc aggagggatc acccagcata ttggagctta ccagattgag gaggcaggca
     4261 agaagattac cttcttggat acaccaggac atgctgcctt cacaagcatg cgtgcacgtg
     4321 gagcgtcagt gacagatatt accattttga ttgtagctgc tgatgacggg gtaatgccac
     4381 aaaccattga agctattaac cattctaagg cggctggtgt tccaattatc gttgccatca
     4441 acaagattga caagccaggg gctaatcctg agcgtgttat ttcagaattg gctgagcatg
     4501 ggatcatctc aactgcttgg ggtggtgagt gtgagtttgt tgaaatctct gccaaattta
     4561 acaaaaacat tgatgagctg ctagaaacag tgcttttggt agctgaggtt gaagagctaa
     4621 aggctgatcc tacggttcgt gcgattggta cggtcattga ggctagactt gacaaaggta
     4681 agggtgcggt tgcgacactt ctggtccaac aaggaaccct acacgtacaa gacccaatcg
     4741 ttgttggtaa cacctttggt cgtgtgcgtg ccatgacaaa tgaccttggt cgtcgtgtga
     4801 aatcagctga gccgtccaca ccggtatcta ttactggtct caatgaaacc cctatggcgg
     4861 gtgatcattt tgcggtctat gctgatgaaa aagcagcgcg tgcagcaggg gaggagcgtg
     4921 ctaagcgtgc ccttctcaag caacgtcaaa acacgcagcg tgtcagcctt gataacctat
     4981 ttgataccct caaggcaggg gaaatcaaaa ccgttaacgt gatcatcaag gcagacgtgc
     5041 agggctctgt ggaagctttg gcagcctcac tccttaaaat tgatgttgag ggcgttcgag
     5101 taaatgttgt tcactctgct gtcggtgcga tcaatgagtc agatgtgacc ttggcagagg
     5161 cttcaaacgc tgttatcata ggcttcaatg tgcgtccaac accacaggcg cgtcagcagg
     5221 ctgatacaga cgatgttgag attcgcttgc atagcattat ttataaggtg atcgaagagg
     5281 ttgaggaagc catgaaaggt aagcttgacc ctgagtatca agaaaaaatg cttggtgagg
     5341 ctattattcg tgaaaccttt aaggtctcta aggttgggac aatcggaggc tttatggttg
     5401 ttaatggtaa ggtaacgcgt gattcaagtg tacgtgtcat tcgtgatagc gtggttatct
     5461 ttgatggtaa gctagccagt cttaagcatt ataaggacga tgttaaggag attgggaatg
     5521 cccaagaggg tggtttgatg attgaaggct ttaatgacat taaggtcgat gataccattg
     5581 aggcttacgt catggaagaa attacccgta aataatcgtg gtggctagta gcttaaatag
     5641 cctcgtctca agacaataga caatgtcacc acttgatttg aacagtcact attaatagta
     5701 tagccatcag cctaatagag aaaaaggctt gaaagtcatc aagcttttct cttgttattg
     5761 agctactgag agcctgtact atttgacaat agaaaggaag ggccatgaca aatcatcgta
     5821 ttgatcgtgt tggtatggaa atcaagcgtg aggtcaacga gattttacac aaaaaggttc
     5881 gtgatccacg tgtgcagggt gttacgatca cagaagtgca aatgctgggc gatttgtcag
     5941 ttgctaaggt ttactatacc attatgagtg acctagcttc agacaatcaa aaggctgaaa
     6001 taggcttaaa aaaagcaaca ggaaccatta agcgtgagct tggtaagcaa ttaaccatgt
     6061 ataaaattcc ggatttggtt tttgaaaagg acaattctat cgcctatggt aataaaattg
     6121 atcaattgct ccgtgagcta gaaaagaaac agtagtcatg ctgtgatcag aaaatgccta
     6181 ccaggctttg gcaaaaaact caagtctggt aggcattttt gtattattat ttttggggtt
     6241 cgtactcttt ttttatggta tcaatgattt ggtattgtgc tgtcttggcc tcttcaatcg
     6301 ggtaaatagg ataaacatgg ttcatctttt ccccgacaaa tagctggtgc ttatgtcctt
     6361 tttgttttaa cataccatca aattttgtaa tgtctgggta gaagatttca tgagttccta
     6421 caaacatggt gataggtgct aggttgcttg tatctccata gatagggcta acataagggt
     6481 gcttagtgtt attttccccg cgtcgtgccc agatatcacc tactatgcgc agtccccaag
     6541 ccgataagat aggatcagag gcttcgtaat ttgggatctc tggatttgat agggtgacat
     6601 caagccaagg tgagagcagg ataatgtcct taggctgctt aatatcttca tttttcaatg
     6661 ctagtgccaa acctagtgcc agaccgcctc cggctgagtc tcccatgatg gtgatattgt
     6721 tagcattgtt attagtgctt tttagaatat cctgataaag actaactaat cttggcatag
     6781 cgacatcata ggtataggtc ggagcctttg ggtaaatcgg caatacaatc ttagcatcaa
     6841 ggctagttga caaggttttg agcatgtcaa tatggtatga ggtcgggttg tttaggtagg
     6901 agccaccatg cagatagaga atgacctttt gatttgatgg attagtagag ttttcattcc
     6961 agctgtgaac ctgcatgttg tctctatact ctgtctttaa tgttccgttg acctcatttt
     7021 gagtgagatt aaagccttga ttgctctttt caccagctga cttgacgtag ttgtagaagg
     7081 tattctcatc ctgctcggca taatagcttt tgtctcgttt aagccaaaaa tattgctcaa
     7141 taaaccagct tttccaggat cgcgtgctgg cctgaacgat tgtttggcta cctatagctg
     7201 tgagtagaag ggctagtaga attagctgtc ttttaagata cgtcaatgtt ttctccttaa
     7261 tcattacagt attactgtca tatagtaata tacaaggact cattttgtca atataaagtt
     7321 aatcagataa gactggaaag ttcagactat taaaagctag ctgctgactt tagctgtcag
     7381 tccttttttg acgctgtttc tcataaagag acctttttta gttattattt gtttacaaac
     7441 gtaaacaaat aagctatact taataaaacc gtagatgaaa gagaggtagc aatatggata
     7501 cgatatctga tgcagaatgg gaggttatgc gtgttgtttg ggctaatggg agcatgaaga
     7561 gctctgagat tattgctatt cttcatgaaa agcaccattg gtctgattct accgttaaga
     7621 ccttgattgg acgcttggtt aagaaaaaag ccctaagggc tgatagacag ggacggtcct
     7681 atatttacca gtccttgctt gatcaggaca ggcgacagct tgctatgcta cgagagaggc
     7741 ttgatggcat gtgtcaacgc caccatagcc gcttgttgct ggcattacta aaggataccc
     7801 caatgaccct ggaagatatt caggcttttc agttgctctt agaggctaaa aaagtcggag
     7861 cagtatccca tgtaaggtgt gattgtgtgc caggacaatg tcattgtcag aaaaaggaga
     7921 ggatatgatt gttaaagaga cctatctatt agagggaatg cactgcacct cctgtgctct
     7981 agcgattgaa caggctgtta agcaactgcc aggtgttgag ggggcagctg ttgatgtgac
     8041 gactgagaag ctatcagtga gctactcaac tgacagcctc agctcagcag agctcattca
     8101 agcagtaaga aaggcaggct acagagcaga gctgcttgat gagaccaata tgagagggca
     8161 actagagcgc ctagaggagc aggctagcaa tgaatggtat cgctttctgt ggtctgctct
     8221 ctttagtctg ccgctgctat accttgcaat gggacctatg cttggattgg tgctgccggt
     8281 cgctctagca cctcagtcgc atgctataag ctatggtctt gttcagcttt tgctgaccct
     8341 gcctgttctt ttcttgaatc ggcagtacta tgaaaatggc tttaaggcat tgataaagaa
     8401 gcggcctaat atggattcgc ttgtgacctt agccactagc tttgctttta tttacagctc
     8461 atatagctgt tttaagattg tagctggagc tgctcaattt gctcaccagc tttattttga
     8521 atctgttgtg gttattctga ccttgattac ccttggcagc tatttggagg ggcgtaccaa
     8581 gggacgggcc tcgcaggcta ttcagaagct aatgtcctta agggtaactg atgtcagggt
     8641 tattcgtgag ggagcacttc agcttattcc cttagagcag gtgactaatg aggatatttg
     8701 ctttattcaa ccgggtgaac gggtggctgt tgatgggctg atagtagagg ggcagtctac
     8761 ggttgatgag tccatgctaa caggagaaag cctaccagtt gataaggtga caggtgatag
     8821 tgtgtttgct ggcacaatca atggccaagg agcgctaagg gtaaagccct ctaggcttgg
     8881 caatgacacc ttgctttcac agattattga gctggtggag caagcacagc aagccaaggc
     8941 tccgattgct gcacttgctg atagggtatc aggagtcttt gtccctatcg tattaagttt
     9001 atccctgctg agctttcttt tttggctctt tgttatgaga gagagctttg attttgccct
     9061 gacaatagct atagctgttt tgattattgc ttgtccctgt gctctgggtc tagcaactcc
     9121 caccgcgatt atggttggct caggtcgtgc agctgagcag gggatccttt ttaagggagg
     9181 agatatttta gagaaggctt atcaggtgcg gacaattgtt tttgataaaa caggaacgct
     9241 gacagagggt caggctcagc tacagcggat catccccctt gctgctagtg agaagcaggg
     9301 acttcaggag gtggcttcct tagagcagta ttcgcagcac cctcttggag aagcgcttgt
     9361 tagagtagca caggaaaagg gctatgactt gctggctgtg actgattttc aatcgcttgt
     9421 gggcttgggt gtcactggtg tgattgacca gcatcgctta gctgttggca atagtgagct
     9481 gatgtcacag caggggattg cgataagcgc tgctcagacc tatgccgagc aagctgcctt
     9541 aaaggggcaa accgtagtgt attatgccaa ggataatcag ctatgtgctt tattgctgat
     9601 tgctgatagg ctaaaggctg acagtaaggc agctataagg gccttgcagg atttaggtct
     9661 tcaaacggtt atgctaacag gagataatgc cctcacagct caagcgattg ctaatgaggt
     9721 gggaattgat caggtcttta gtcaggtgct gcctgctcaa aaggcccaga ttatcgcgga
     9781 tttgaaggct agcggacagc tggttgctat ggttggtgat ggaatcaacg acgcaccggc
     9841 cttgacccta gcggatattg gaatctcaat aggctcaggt acggatattg cgattgaggc
     9901 ggcagatgtt atcctgatga cctcagcagt gcgtgatgtg gtggaatgcc tagagctcag
     9961 tcgtcaaacc atcagagtgg ttaagcaaaa tttattttgg gcgtttagct ataatagcct
    10021 aatgatcccc gttgctatgg gtatccttca tgtctttggc ggccctctat taagcccaat
    10081 gctggctggc tttgcgatga gccttagctc aatatcagtg gtgttaaatg ctttgcgatt
    10141 aaggcataaa aaatggtaaa ggctctcacc gaccttaccg tcagtatagt aaagctaaag
    10201 gcctgcgccg acaaaaggca taaacaaaac aaagagcagg aataaaaaag cagatcattt
    10261 attggttaag gctaccagaa gccaccaagt gctatagcaa cctgatatgg caaatagcac
    10321 cgaaaaatat gacaggtata ggataacctt acattatcgc tgagagattt aaaggtgcta
    10381 ttattgttac cgatcatagg tttcttcata ttgacaccac tttttagctg ttaatatgag
    10441 aagacggttt aagcaggctt cgtattttgg ttgagaatag actaagtgaa ttgttctatg
    10501 acaaagaaag gataacaggc tttatgagtt aatagggtgt cattagctcc cggcttattt
    10561 tttgactaac atcaacagaa gagcagtaaa ccaagcaagg gtttgctgtt ttttcttgct
    10621 cagcatgaga cggaaaaagt gagcataaca agcaatcaaa aagagcagct gaatcatggt
    10681 caggcaaaga cagcatgcga agaacaagct gaatagtgac tccaaaagaa gggctggcgc
    10741 tgatagtctt gatctcatag aggcctttat ggtttccgct gataaacggg ggtattgctc
    10801 acaacatgat taggtaaaaa agagcacgat gatgtctata ttaacattat gtggttatta
    10861 ttgagcgtca tttaaatata ataatagaaa aaatagttta aaaatggtat aatattataa
    10921 attagctgta acgcaattgt catttatagg ttaagcaaaa gcataaagtg actggtgtta
    10981 tcaagagcag ctgagcgctg ctgatggaga agtatctgga gtaagtgaga tgaacgaaaa
    11041 tactaagcga ttgacagatc ctattgtttt ggagaagagt agagctatag aagcttcgcc
    11101 tgagcatcac caaaagctgg agcaaattaa aagcgagatg agtggaaatg ctagaaagaa
    11161 taatctgggc tggctggcaa tggtgatagg cgcaatcatc ttgtatggca tggttgaccg
    11221 atctcttgcc ttatttctca ttatctttgt ggggggcttg gtttggccgc ggctgaaaac
    11281 attcaaaaca gcaaatgagc tctcctatgt ggatcacttt ttgctgcctg ttttacaaga
    11341 ggccctgcca gatgtcaaga tagattacta ttcagggatt gagctctcct tactaaagct
    11401 tgcaacaccg tcctccagat ggtatgacag taattgccat attatttttg gagatgacat
    11461 gcagacagaa ttttgcaatc tttatgccta ccatgaggaa aatgaggatg ataactggca
    11521 tcgggtcact gattttaacg gacaggtgct gctggctaaa tatcatacag ctatcaaggg
    11581 ttatattaga attgtgccga ctcaaaaggg ctttttgggc agagaaaagg tccatagtgg
    11641 ctacaaggct aagctaaagg gtgaggtgca gctggaaatg gaggacattc gctttaatga
    11701 aacgtacaat gtgtactgca cagatgaatt aagcgctaga atgctcttaa atccttatat
    11761 gctggcagtg cttgatgaat ggagagagga gatgcctgta gcagtttata tgaatggtga
    11821 tactgttgtt gtgtccttct attccggtca acagctcttg aaaaccccta gctctagagg
    11881 ggctattgaa aagctatcgt taagtagcga atatgaaaac attcaagaca agcttgttaa
    11941 gatgtaccgc ttgttggata cactaaatca tcagctttaa ggaggctttt ttatgtcagt
    12001 gacgtcatct atgttaacac ttattctttg catgactata ctatggctta ttggagtgag
    12061 aaacaaatta gaaaggtatc gaatcgttat agaggagtct aaacgaaatg tcgatattgc
    12121 tcttgagaag agatatgata ccatttcgga aatgctaaaa atcgctaagt cctatgccaa
    12181 gcatgaggaa aaggtcttta ctgaactcgt gaagctgcgt caggggcttt ccttggagga
    12241 aacaaatgat gtgatgagga cacaggagca ggccttgaat gaggtttttg ctgtaggaga
    12301 ggcttatccg gaaatgcgct cctctgagca gtttttgagc ctgcaaaatg agattgctaa
    12361 ggaaaatgca gccttggcag cagcaaaacg cattgtcaat agtaatatta gtctcttcaa
    12421 tcaagcggtg gttgcttttc cggtatcaat tgtagccagc cttatcaata tcaagcagat
    12481 gacctttctt gatattgacc ttgaccataa aaagagtctt gatcagctgg actataccat
    12541 ttaggctgtc tgctcgttaa gaggtgaggt aggtaaatag ctgttagaaa gcggctaagc
    12601 tgtcgtatga gccctttcac agccctcagc gtagaaaaag agtggaataa ccattcaatc
    12661 gtcatgacct ggcgatgttg attaggttat ccaccctcga gcagctgatt aaaaaggcca
    12721 catcgcttga aaaatgaggg ctaagagccc tccaatcaac tctatagttt gacgatttta
    12781 aaagaggaag gatttttgtc ctagcctctt tttgctttgc ttaacgtgtg ataggttaaa
    12841 aaaggcatga agccccattg caatattagt ggcttcatgc gcttttatga tgctatttcg
    12901 tttgatagct ttgtttacct gctggactca gggtggaaac agatagagag gcaggctgtc
    12961 tagctgctga cctgattgtc agctggcctt gcgattaaga gcttggcaaa ttggcggtaa
    13021 cgctccttaa cgctgtcact aatcttggag tcagtgataa tggcgtcgat attgtcaagg
    13081 tgataaaagc tgtaaaagtc ataggcgtta aacttttggt tgtcagcgag caggtatttt
    13141 tcgatggcat tgtcacaggc taggcgctga ataacccctt cgttttcact gtaggtggca
    13201 atgtcatttt tataaatacc gttgcagctg atgaaggcct tggcaaactt caaggataag
    13261 atggtctggc ttgcaaggct gccaacaaag gctcctgtga tggctcggta ctcaccaccg
    13321 ataagaatga gatcaacagt tttactttta ttaagaatcg taaaaacagg cagactgttg
    13381 gtaataatac ggatgtgacg gttgattaga gcctcagcca agcattctag tgttgtccca
    13441 gggcctataa aaatggtctc accatcatta atgagctgac tagcgtatct ggcaatctct
    13501 tttttagctt caatttgtac ggttagcttt tcagtgtttg aacgctccag cttttgaggc
    13561 atagaaatgc tctgggcacc gccacgaata cgtactaatt ttccagccct tgctagctca
    13621 tctaaatttc gcctggctgt catatctgaa acccttaggc tttccataat atcagtgaca
    13681 gtgataaagc cgttggcgtt taccttttcc ataattgtta acaatctttc acgcttaagc
    13741 ataggccgct actttctctg gtgtattgtt aactcataat agcataaaca gtctcttttt
    13801 tcaataaaca acaaaataat aaaaaacaaa acaaaaataa acaattttga acggtaatga
    13861 caataaaagg agatcctatg actattatct taggtgcaga tgcacatgga aatgatctaa
    13921 aagaggctat taaaggcttt ttgcagcagg aaggctttga tgtgacagat gtgacggcga
    13981 ttgctgatga ctttgttgac aatactctag cagttgctag ggcgctcaag gctgatgagg
    14041 aaagtctagg cattatgatt gatgcttatg gagcagggcc atttatggtc gctaccaaaa
    14101 tcaaaggtat ggtcgctgcg gaagtgtcag atgaacgctc tgcctacatg actcgcggtc
    14161 ataacaatgc ccgcatgatt accatgggag cagaaattgt gggtcaagaa ttggctaaga
    14221 atattgctaa aggttttgtg actggtcact atgatggtgg ccgtcatcaa attcgtgttg
    14281 acatgctcaa taaaatggct taacgaaggg aggatatcat gaaaattgct attggctgtg
    14341 atcatattgt gactgatgaa aaaatggctg tttcagattt tttgaaatca aagggctatg
    14401 aagtgattga ctgtgggacc tatgaccata cccgcaccca ttacccgatt tttgggaaaa
    14461 gggttggtga ggctgtcgcc aatggcctag ctgatcttgg tgtctgtatc tgtggcactg
    14521 gtgttgggat cactaatgct gtcaacaagg ttcctggcat tcgctcagcg cttgttaggg
    14581 atatgacaac agcgctttat gccaaagaag aattgaatgc caatgtgatt ggctttggtg
    14641 gtaaaatcac aggtgagctt ttgatgtgtg atattattga ggcctttata aaggcagact
    14701 ataaggaaac cgaagagaat aagaagttaa ttgctaagat agcccatttg gaaagtcata
    14761 atgctaacca agaagatcct gacttcttta cagagttttt ggacaaatgg gatcgcggtg
    14821 actaccacga ttagggagaa gcgatgattt taacggtaac cttaaaccca tccattgata
    14881 tttcctatcc tctaaatcgt ctgactttgg acacggttaa tcgtgttgac agaacgacaa
    14941 aaacagccgg tggtaagggg ctgaatgtga ccagagtgtt agcagaagct ggtcagtcag
    15001 ttgtggcaac aggatttatt ggtgggaaac tgggtgactt tgtcattcat cagttacaag
    15061 aacagggcat ttctaaccaa ttcttcaaaa tcaaagggga aacgagaaat tgtattgctg
    15121 ttttacatga aggcatgcag acggaaattc tggaagctgg tccctacatt gatatggacg
    15181 aggccgaagg ctttttgaac cacatgagta ttattgctaa gcagtttgat gtcttaacct
    15241 tttcaggcag tctgcctaag ggtctggccg ctcactatta tcaagacttg attactatgg
    15301 cgagagtcta tggcagcaaa gtggttttag attgctctgg tgctccttta aaagcggtac
    15361 tggctggcaa agataaacca actgttatca aacccaattt ggaagaattg gaggatttga
    15421 taggccaacc tgtcacatta gatgaggaac gtttaatctc tctgttgagt caacctttat
    15481 ttgaagggat agaatggatt attgtttctc ttggtgccca aggggccttt gccaaacatc
    15541 ataacaggtt ttaccgtgtt accattccta aaattgaggt agtcaatcct gttggatctg
    15601 gtgacgctac tgtggcaggg attgcttggg ctttggcaga aggagatgac gatgagacgc
    15661 ttctgaaaaa agccaatgtt ttaggcatgt taaatgcgca agaaacaaga acaggtcatg
    15721 ttaacatggc acattttgat gagctatttg accgtattca agtagaggag gtataagatg
    15781 acattaacaa gaaacaaaaa agcttattta gaaaaggtca gtcgtaaggg aatcatttcg
    15841 gccttggcct ttgatcaacg cggggcttta aagcgcatga tggcagccca ccaagacaca
    15901 gagccagctc cttggcaaat cgaagcccta aaggctctgg tatcagagga gctaaccccc
    15961 tatgcctcct ctatcctgct agaccctgaa tatggcctgc cagccactaa ggtacgtgat
    16021 gagaagtctg gcttattatt agccatggtg agaccgaaat cattcataat ggcaagggag
    16081 aaaaaggcgg ctccaaatat cagataaagg gggttggtca acgcgtgttt gatgttgatg
    16141 tgccgcgtac agactgggat tggatgatct atccacaggg gctttacgat caaatcatgc
    16201 ggatcaaggc agactatcca ggctataaaa agatttatat cactgaaaat gaccttggct
    16261 acaaggatac ctgtattgat ggcaggattg atgatgacgc tagaattgat tacatcaagc
    16321 agcatttggc tgtgattgca gacgctatcg gtgctggggc taatgttaag ggctatttta
    16381 tctggtcctt gatggacgtc ttttcttggt caaatggcta tgataagcgt tatggcctct
    16441 tctatgttga ttttgaaacc caaaagcgtt accctaaaaa aagcgcttat tggtatcagc
    16501 agctagctac cacaaaaact atttcagtgt aatctcctaa cgaaaagcac cggcacaagg
    16561 gctgcaaggc ttcaagagct ggtgcttttc ttttttatgc tatactggta acgatgaggt
    16621 catgacataa agagataaca agtgggttgt agcaacctcg tattagctgc cagctgctga
    16681 taatctcatt tggtgatgat ggagagtacc agcttgaatg actcattaaa aaggaggtta
    16741 tgatgaaaaa agtaatgatg tctttgctaa tccttgctac ggcaactctt ggggcttgcc
    16801 aggcttctca ccagtctgat cagcccaagc aggagcaaaa agagccacag gctaagaagg
    16861 gacgtctttt cctatccaac atgaacagtg caaagagcca gcaggaggtc agggctgccc
    16921 tatcacatca gctgaaggaa gctaatgtca atgcctttat ggctggtgta caagaatata
    16981 atagcctagt tggcaaaaca ggcttgacag gggcctttac ctatcagaag cagcctgact
    17041 atgatgtggt agcaatcgat gagttgtggt cgcaaaagca aggcaatttc attggaacta
    17101 attgccggat caacaccttt atgcttctaa aggatagcat gacgattgcg cctaccagca
    17161 gtgatgatac gcttttattt atggacgagg acgccattac cacaagccag ctctttacac
    17221 aggcagagac agagcgcttt aagcagctgt tttcaagagt gaaaacggaa gccaccaagg
    17281 atattcaggt gcatgccaag catatgcaag agcatttctc agctgttagc tttaatggcc
    17341 cagccaaaat gcttgctgtt gtgattcacg atcagctaga tggtgattac ctttttattg
    17401 gtcatgtggg agtgctagtg gagtataaga gcaagtatct gtttgttgag aaattgtcct
    17461 tccaagagcc ctaccaagcc atcctctttg atcaaaaaca ggattgctac caatacctct
    17521 accataaata caagacctat caaaccaaga catcagcaga gccctttctc atggaaaata
    17581 acaaggctgt gaatttggca agctatcgct cctaactcct gctactagga gcctagccta
    17641 tataggggct aaatctttgg tgcaaacaaa aacaggtcat cagtaggatt tttgaggacc
    17701 ttgctcttat tttgacttat attttgatta aaaagatggt agactaatag gggattagga
    17761 agcattaggt gagttatgac aattgatatg tgggagcttt taagcattat tggaacgata
    17821 gcctttgcct tgtccggcgc tattgtcgct atggaggagg agtttgatgt tctggggatt
    17881 tttattctag gctttgtcac agcctttggt ggtggggcta ttagaaatac cctgatcggg
    17941 ctgcctattg aagccttgtg gggacaaaga ccagaatttg cctgcgcttt tatagctatt
    18001 attctgatca tgctatttcc taagcttgtg gctaagggct gggtgagagc agcggtgctg
    18061 actgatgcta tcggacttgc agcctttagt gttcaggggg ctctacatgc tgttcgacta
    18121 gcccagccct taagcgctgt tattgtagca gcggttctta caggggcagg cggaggtgtg
    18181 gtcagagatg tcctggcagg ccgtaagcca actgttctta gaagtgagat ttatgctggc
    18241 tggtctatta tagcagcact tgtgctttat tttaagctgg ccacttcaaa tgttgaatgc
    18301 tacttgctgg ttgttttatt gacagtcatg cgtatgattg gcaacaaaag acaatggcac
    18361 ctacctaaga taaaatggaa agaggactga gacgatgatt cagcttatag caattgattt
    18421 agacggtact ctgcttgata gcaaaaagca cattccaaaa gagaatatta aggctatcca
    18481 agcagctgca caagagggga taaaagttgt tctctgcaca ggccgccccc agtctgggac
    18541 aaggccgtat tttgagcaat taggcttgag tgataaggag gagtacctta ttttaaacaa
    18601 tggctgtagc acctatagga gcccaagctg ggagctgcta cattatcaaa gcctgacctt
    18661 ttcagctatt gagcaccttt atcagctgtc tcagcccttt tcagatattt acctcaccct
    18721 gactggagag cgtgattatc ttgtgataga tagcaaggtt ccagatatgg ttcaggctga
    18781 tggtgatttg gtttttacaa aggtaaaggc tactaaccta tctcagttat ccaacagcag
    18841 tcaaatcata tttcaggcca tgtacatggg agaaaaggct gccctagata cttttgaggc
    18901 tcttgttaga gaaaaactca gcgcaagctt tagtgtggtt cgcagtcaag aaacaatcct
    18961 agaggtaatg ccggagtgtg tgaccaaggc ctctgccctg aaggaattaa ccgctgatct
    19021 gaagctgcgc ccagaccaag tgatggcaat tggagatgca gcaaatgatc ttgaaatgtt
    19081 agcctatgct ggcttaggtg tcgctatggg aaacgctgat gaggcaatta aaaaggtcgc
    19141 tgacaaggta agcctctcca atgatcaagc aggcgtggcc catgccatta atcaatttgc
    19201 attgacaaag ggctcttaag cacagtcaaa ccagcccgtc agaaaaggcc tccaaaagct
    19261 agagatgata agctcagttt tagaggtgtt gactagagct gagctgtctt ggaacaccac
    19321 aagcctaggt gtgtgagatc gactgaaaaa taaaacacga aaaaacctcc aacaaaggag
    19381 gttctggatt gaagagcagg ctaatccagc cagcctcttc agtctttttt tattgtccag
    19441 ctaaatgtaa gagcctttaa gcctctgcac aacagcgagc gacaagtcac accttgcctg
    19501 tagtagggct agtacatatc ttggtaggca gtgccagtgc ttaagtcaag ccagccaagc
    19561 gtcctgtctg atgctgcaag cttggtttct tgggaagttg tctaggagct ataggtgatc
    19621 tagagacaac taggctaata agggcagccc catagcagcc atctcctcag caggaacaac
    19681 catatcatca gaaatccaat tggaaaggac tgagacaata gcgttgctcc aaaagagcag
    19741 tgcgtagtga gacagctttt tttcctgcca cttttggtag gctctcaaac gcttggtaac
    19801 catctgcgtc aagagctgct gcaggtgatg gttaaagata atactaagta gcgtcgcttc
    19861 ttttttggcc tctgtaaaca gataaagcca tgcctgatag gcctgtgtct ttagatcaaa
    19921 ggccttcagt ccacgaaaga tacgtctgat aacagaagtc aacagacact caagaatatc
    19981 ctcctttgag ctgtaattgc ggtaaaaagc atttcttgaa accccagctc tagctaccaa
    20041 ttctgaaatg gtaatgtgtc ctaagggctt cttttctagt aagctaagca gagcaatttc
    20101 aatagcttct cgtgttaacc gtctggattc ctgattgcag tgggctaaat tttgaaggga
    20161 ctgtttagaa attggtttac cagccattac aaataccttt caagtgttac atctgatgtc
    20221 gtttagctag caaaagtcta gctagtgatg atataatttt atgggaaaat gcttactttg
    20281 tcaaccaaaa cagactatga aggaaaagag gaaaacgaat gacctggaaa attgtatcgg
    20341 attcaggctg cgatattaga gccctaaaaa gccaatccaa tcacctgcgc tttgagcgtg
    20401 tgccgctaac cctacagatt ggttcagata tttttagaga tgatgatggt ctagatattg
    20461 atcaaatgat ggagactatg tatcagtcct ctaagccagc aacctcaagc tgcccaagtc
    20521 ctgatgcttt tttacaagcc tacaggggag cagataacgt cattgccatt accattaccg
    20581 gtacgctctc aggcagtcac aatagtgcta gattggctca aaatgacttg cttgaggaaa
    20641 atccgaatgc caatatccat gtgattgact ctttgtcagc aggtggtgag atggatttga
    20701 ttgtgttaga gctagagcgg ttgatcaatc aggggctttc ttttgatgag gttgttgaga
    20761 aaattacagc ttatcaggaa aaaaccaggc ttgtttttgt gttggccaag gttgataatc
    20821 tggttaaaaa tggccgtctg aataagctca ttggtaaggt gattggctta ttaaacatca
    20881 gaatggtagg acaggcaagt aaggaaggca cgcttgagct gcttcaaaag gccagaggtc
    20941 aaaaaaaggc agtgtcagct gttttagaag agattcaaaa ggcaggctat aaaggaggcc
    21001 gagtctttat ctcccacgcc aaaaacccta agatctgtga gcaaattgcg gaaaaaatta
    21061 gagcgattta cccagaagca gagattcaaa ccagcccagc ctcaggccta tgcagcttct
    21121 atgcagaagc tgaagggctt ctcatgggct atgaggttta agctaagcaa agtgatctaa
    21181 cgctgcctct ggtttctgtt agtcatagag gctgagctat gcacagcttg actctagcta
    21241 gtggtcggat aggcataggt ctttatcaca agtctttagc tgagagctgc cttaacaaat
    21301 atccctgata ctatagaggc attaagctga atacaaggtc cttaaaggtg tgtttaaggg
    21361 ctttttgttg tgcatgctaa tcacctcgtc agtcccttaa aagtcttagg gagtgacact
    21421 gaggaaaaaa ctcaaatggt caagccagtc agaatatcca tgacgaatca ccaaagcgcg
    21481 taagggtgag ccgctctata atcatagcca agctgataga gagttaggag aggatatggg
    21541 attacttatc gacttgatta agcctccctt ctcttcctac ctcaaaatca attaagaagc
    21601 acaaaaacag ctggaatcct tttagaacca gctgttttta atcacctaaa gcctcttttt
    21661 atcagagagc ttattagtcg taagtttagc attatttcag tagctaagcc cttattgcct
    21721 gtactaagaa gtgtaactaa gctacagcag ctctggctgc cctttcttag ttttgtcctg
    21781 ctggagcagt gttttcactt tgctctgttg caggtggctg agggctaggt gtgttggttt
    21841 ctggttgagg atttggctga gggttaggac taggcgttgg ctctgggttc tctggagctg
    21901 gactaggact aggctgagga ttcggcttag gactaggttt agggttcggt gctggcgtcg
    21961 ttcccccaga agacggtgtg gtatgcttta tttgtggagc cgcaggagct ggtgctatat
    22021 ttttttctgc tgctggtgtt gcagtctcag gctgtgcagt gctaggcttt gaaagtccaa
    22081 tagcgtcaag tctagcctgt aaggcagctt ttttagcctc atcagagagc ttactaatgg
    22141 ctttttgtgc agcctcctta agttcagggc ttggattgtc ctcggctgcc tttaggacct
    22201 tgatagcaac gtcttcttga ttgtgcttta agctgatagc tgttagtcga gcctgtaatt
    22261 cctccttaga ctgggtcttt tttagctgat taattgcttt ttgagccttt gcgatagctt
    22321 ctttagttgg gttgtcttcg gcctccttga ctaatgcttg agccttagtt aacagctcat
    22381 agcccttaga ttgggtggta atggtagctg gctttggaga gaggctacta aaaataaggt
    22441 aggcccctcc tgcaatggca atagtaagca agctaatgat gaggtagtgg gtctcttttg
    22501 tcggttttct catggtatct cctttgaaat cattgtcgct tgagtagcac tattataccc
    22561 tgaatatagg aaaatgaaaa gaggactagg gctctaaaat aggttctaaa tgagcactat
    22621 ttaaaaggat taaaaaaccc ttgtgataac tgaataaata cattaaaata gaagagaata
    22681 aataagcgag tgaggacaat attgtgtcgg taaattggca agacattgcg tttcattttt
    22741 tggggggcag tacagggctt aggtcttttt cttttcagta tcaaatacat gggagacgac
    22801 ttgcagcagg ccgcaggtga taagcttagg tattacattg acaagtacac aagcaacccc
    22861 ttctttggta tcttggttgg aatagctatg tctgctttga ttcagtctag ctcgggtgtg
    22921 acggtgatta cagttggcct agtatctgca ggccttttaa ccctacagca ggcgattggt
    22981 attgtcatgg gggccaacat tggaacaaca gtgacctcct ttttgattgg ttttaagctg
    23041 ggagattacg ccctgcccat gatttttatt ggagcagcct gtctcttttt cacgtcaaat
    23101 aaaaaactca ataacctagg tcgtatcatt tttggtgtag gaggaatttt cttttctctc
    23161 aacctcatgg gtgatgcgat ggatccttta aaatcagtct cagcctttca gcattaccta
    23221 gcgacgcttg gagacaagcc ctttcagggt gtttttatcg ggacagcatt gaccatgctg
    23281 attcaatcct cggcggccat tattggtatt ttacaggggc ttttttcggg tggcctattg
    23341 accctgcagg gtgcgattcc tattttgctt ggctctaaca ttggtacctg tatcacagcg
    23401 gttttggcag ctattggctc taatattgca gctaagcgtg ttgctgctgc tcatattctt
    23461 tttaatgtta ttgggacggt catctttatg attttactga tgccatttac ctcctttatg
    23521 ctatggcttc agtctgtttt ggccctgtca cctgagatga ccattgcctt ttcacatggg
    23581 acctttaaca tcacaaatac cctgttgctg cttcctttta tcaacactct ggcaaagctt
    23641 gtgaccacct taattccagg tgaagacgaa atcgtcaaat atgaagcctt gtatttggac
    23701 cgtttactaa tcactcaggc tccttctatt gccttgggaa atgcccacaa ggaattggta
    23761 catctggctt cctatgctat tcaggctttt gaggcgtctt atagctacat tatgacagca
    23821 gaagacaagt ttggcgaaaa ggtgaggcga tatgagaagg cggtcaatac gattgatgag
    23881 gagctcacca cttacctcgt tgatatttcc aatgaagccc ttagtcctag tgaaaatgag
    23941 gttttagcag gtctgttgga ttcgtctcgt gatttggagc gaattggtga ccactctgag
    24001 tcgttagcga ctctcattga ggggattaca gcaaagcaga ttggcttttc agcagctgca
    24061 cgtggtgaat taacagaaat gtatcacctg acccactgtt taactttaga tgcgattagg
    24121 gcgattgtgg atagtgacaa ggctctagcc cagtctattg ttgagcgtca taggacgatt
    24181 gagcaaaaag agcgtcaatt gcgtaaaaca cacatcgaac gcctcaatcg tggcgaatgc
    24241 acagcacagg cagggattaa ttttattgac attatatctc attacacacg tatcactgac
    24301 cacgccctaa atctagctga gaaagtactt tcaggacagc tctaataaaa gggaaaactt
    24361 gaaatagtat tcaggttttt ctttttaaca gaaggactgg tatataccat ttacaaaata
    24421 agaattaagg cgtataataa acgaaaaagg gaggaaaaaa gatgacaagc tatattaaag
    24481 cagattgctt ttattacccc aacgaggtaa agccagcagg ctatttggag ctaaataatg
    24541 gcacatttgg ttattggacg gctactgttg atgatcaggc agaggttatt gattatacag
    24601 gctatcaaat agcaccagga cttgtagata ctcatattca tggctatgct ggtgctgatg
    24661 tgatggataa ttcagcagaa ggtctccatg ccatcagtga gggtctctta tcaacaggag
    24721 tgacctcctt cttaccgact accctaacgt caacctttga gcatctagag caggtgtctg
    24781 caaccgttgc ttctgttgcc gatcaggtca aaggagcaaa gattcagggg atttattttg
    24841 aagggcctta cttcactgag gaatacaagg gagcccaaaa cccgatatat atgaaaaatc
    24901 ctcgcttaga cgaatttgca gcttggcaaa aagcagctaa gggcttgatc aaaaaaatag
    24961 ctttggctcc tgagcgtgat ggcgtagaag catttgtctc tgaggtgacc aagcagggtg
    25021 tcacagtagc tttaggtcac tcaaatggta cctatactga ggctaaaaag gcagtagcag
    25081 caggagctag tgtttgggtt catgcctaca atgggatgcg tggcttgact catcgtgagc
    25141 ctggtatggt tggggctgtt tataatattc ctggaacggt tgcagagctg atctgcgatg
    25201 gtcatcatgt ctcacctgtt gcttgcgata ttttgatgca gcaaaagggt catgagcatg
    25261 tggctttgat tacggactgt atgcgtgcag gcggttcacc agatggtgat tacatgcttg
    25321 gagagtttcc ggttattgtg gaaaatggca cagctcgctt gaaggatagt ggtaatctag
    25381 caggctctat cttaaaatta aaggacggca ttaaaaatgt tgttgcctgg ggaattgcaa
    25441 gtccagcaga agcaattcac atgtcctctt acgtcccagc tgcttcggtt ggtattgaag
    25501 atgtctgtgg ccaaatcaag gcaggtcatg ctgctgactt tattgttctt gataaggact
    25561 tagaattagt agcaacctac ctaaatggtc aaaaggcctt tgaggcttaa tacagcaaag
    25621 gaattgggct ggtgatcagc tcaattcttt ttgctttgct tatcattgtg ctacaatgaa
    25681 aaaggaggtt ttagatatga ttaaaacagt aacaatggct aatggtcttg ctattccagt
    25741 gcttggcttt gggaccttta aggctgctga tggtgaggag gcctaccaat ccaccctagc
    25801 agcgattaag gcaggctatc gtcatattga cacagctgcc atttatcaca atgaaaaaag
    25861 tgttggacag gccattcggg attcgggcgt tcctcgtgaa gaactcttta ttaccactaa
    25921 gctctggaat gatgctcata gctatgatgg cgctaaggca gccttagcag cctctcttga
    25981 gcgccttgga ctagagtatg tagaccttta tctgattcat tggccaaatc ctaaggctct
    26041 tagggattgc tggcaagcag ccaatgcagc agcttggtct tatatggagg aggctgttga
    26101 agcaggcttg gttcgctcga ttggtgtcag caactttatg gttcaccatc tggaggctct
    26161 taaacagaca gcaaccatta caccagcagt caatcagatt cgcttggcgc ctggctgcta
    26221 tcaaaaagag acggttgatt attgccgcag gcatcacatt ttgctagagg cctggggtcc
    26281 attaggacaa ggagagatat ttgccgatga taccatgcag gcattggcta aaaagtacaa
    26341 caagacagtg gctcagctag cccttgcttg gtctattgct gagggcttta ttcctctacc
    26401 taagtcggtg cacaaggaac gcatagtaga aaatatggct atttttgatt gtgagattag
    26461 tccagaggat tcagagcgca ttcgttgcct gccgggtatg tcagctatcc cagatcctga
    26521 taccaaggac ttttagcaag agctgcaggg attaagtgag ctacattagt ggtccttgct
    26581 cgtgctttgg tcaaaacacc gcagctgtta ttggcagatg agccaacagg cgccctggat
    26641 attgaggctg agcaggaggt cttacaagcc atcagagctt gtcagactga ggatatgatt
    26701 gtcttaatgg caacacacag cgatgaggtt gcagcgcaat gtgacgctat ttaccatatt
    26761 gaggatttgt gtttacgaca ggcgaagtag gtcaggcctg caaaatgcct cttgggtgct
    26821 gcttgctgct cgtgaattga ctgagtctag gagctgtctt ttgatggtga tttggtacga
    26881 ccttaaagct ttgatgaggt ctcttgatgg tgctgtgtga cgacctcttg tttttagaga
    26941 tcaaagaaag acatcttttt tttgaaaacg gtttgacaag gctgtgtaac ttagctataa
    27001 tcttaattag tgtttcgtga aagaaacaga ttaaactaga ataaaggagt cttactttga
    27061 ttatcctgtt attgatgctc ttgatgtttg ctattcgttt agtattctta aaaaaatcga
    27121 tcaaaaacga gaaggctatc ctggctaatg ggggcaagga atttggtgcg caaaacacta
    27181 agtttttgac cctgctgcat atcatgattt atgtctttgc tgtgacagag gcattgctca
    27241 agcagattaa gtttgatggc attagctttc ttggcttgct gctgatgatt ttttcgatag
    27301 ctgtgctata tgaggtaact cggatcttgg gagatatttg gacagtgaag ctgatgctgg
    27361 caaaggacca taaatatgtc gatcattggc tctttaagac tgttaagcac cccaattact
    27421 ttttaaacat tgctccagag ctggttggta ttgctttgct ttgccatgct cagattacgg
    27481 caatgctgct tttcccttgc tatattattg tgatttatct gcgcattcgt gaagaaaata
    27541 ggctcttgtc tgaggttatt attccaaacg gaactcgtcc aaaatcataa tagttgatta
    27601 gacaatcata ggattttgtg ataaactaac caataggaaa gaaaatagca ggtttctgat
    27661 ctaaagcgag ctcggggctg gtgagagccg agtgatggta ctgctggttg gcgctttctc
    27721 taaagagtag gctcaggtgt ttgtagcttg cttgacatct gtttatcaac aagatcaaat
    27781 gaagtaataa attagggtgg aaccgcgttt tgacgcccct atgcctttag gtgtaggtgg
    27841 ctataggcgc ggtttttctc tttgaaaagc tgtttaagag ccaaccagca gtcaagccat
    27901 agccagctct tggttagcgc ctgcgacaag acataaaaaa tagaaagagg aaatcatgag
    27961 taacaaactt acctttcaag agattatttt gacgctacag caatattgga atgatcaagg
    28021 ttgtatgcta atgcaagcct atgacaatga aaaaggagcg ggaaccatga gtccttatac
    28081 cttccttcgc gctattggtc cagagccttg gaatgctgcc tatgtggagc catctcgtcg
    28141 tcctgctgac ggccgatacg gcgaaaatcc caatcgtctg tatcagcacc atcaatttca
    28201 agtggtgatg aagccttctc caagtaatat tcaggagctt tacctgcaat ctcttgaaag
    28261 acttggcatt gatccattgg agcatgatat tcgatttgtt gaggacaact gggaaaatcc
    28321 ttcaaccggc tcagctggac ttggctggga ggtctggctt gatggtatgg agattacaca
    28381 atttacctac ttccagcagg tgggaggcct agcaacatca ccagtgacag cagaggtcac
    28441 ctatggctta gagcgcttgg cctcatacat tcaagaggtg gattcggtct atgatatcga
    28501 atgggcacct ggtgttaagt acggcgagat ttttcttcag ccagaatatg agcattccaa
    28561 gtattccttt gaggtatcca atcaggacat gctgcttgaa aactttgaga tatttgaaaa
    28621 agaagcagag cgtgctttag cacaagggct tgtccaccca gcctatgact atgtcttgaa
    28681 atgctctcat acctttaacc tgcttgacgc tcgtggtgca gtctctgtga cagagcgtgc
    28741 tggctatatt gctcggattc gtcatttagc tcgtagcgtt gctaaaacct ttgttgcaga
    28801 gcgtaaaaag cttggcttcc cattgttgga tgatgctagc cgagtagcct tgctggcaga
    28861 ggactaagca gctggatcta aactagttcc ttgtagtcaa tgcagcttgt atgatcttgt
    28921 aagctctagt tgctgctagc agcttaccta tctggtaggt gctttttaaa agcgatgaga
    28981 cttaaaggcc tgatgactag tcctgttaag ctcagtcttt ctgctaagtg atcttgtcta
    29041 acaggcagct tattagcagg cttgcaggat taggagctag tgatttggtc tcctaaacct
    29101 accccataac ttgaagaaag gaaagaaaga tgggacaaat cttgtagaca aaggatcgtc
    29161 caagcttgcc caaggcatgc taggatcggt ttggtcttct cttttagatt tgatgcccat
    29221 aggattttaa tgatgacaaa agatttactt gtagaacttg gtcttgaaga gcttcctgcc
    29281 tacgttgtca cacctagtga aaagcagctt gttgaacgta tggctgattt tcttaaggcc
    29341 aatcggctta gctatgacgc aatcgaaggc ttttcaacgc cccgtcgttt agcagtgcgt
    29401 gtgctgggct tagctgatca gcagactgat ctgacagagg attttaaggg accctctaaa
    29461 aaaattgctc ttgacgcaga tggtcaattt tcaaaagccg ctcagggctt tgttcgtgga
    29521 aagggcttga ctgttgatga catcgaattc cgagaggtca aaggtgagga atacgtttat
    29581 gtcaccaagc atgaagcggg caagcaggct aaggacgtct tagcagcggt gccagaggtt
    29641 cttgcttcct tgaccttccc agtcagcatg cactgggcta acaatagctt tgactatatt
    29701 cgtccggtgc atagcttgat tgtactgtta gatgatgagc ctttggagct tgacttttta
    29761 gacattcatt cgggacgtat cagtcgcgga catcgcttcc ttggagaaga gactagcatt
    29821 acaagtgctg attcctatga ggctgacctg cgcagccaat ttgtcattgc ctctgctaag
    29881 gagcgtcaag agatgatcat agcacaaatc agagccatcg aagcagagca aaaggttcag
    29941 gtggatattg atgaggacct cttaaatgag gtgctcaacc tagtagaata cccaactgcc
    30001 ttcatgggaa gttttgatcc caagtacctg gaaatcccag aagaggttct agtaacctca
    30061 atgaagaacc atcagcgtta ttttgtcgtg cgtgatcagg ctggcaagct aatgccgaat
    30121 tttatttctg ttcgtaacgg taatgctaag catcttcaaa atgtgattaa gggcaatgaa
    30181 aaggtgcttg ttgctcgtct tgaagatgga gaatttttct ggcgtgagga tcaaaagcta
    30241 tctattgaag atttggttgc taagctagct catgtgacct tccatgaaaa gataggctct
    30301 gtggctgagc atatggagcg gaccaaggtt attgcagcct ttcttgctga ccaggctggg
    30361 ctctcagaag cagaaaaaag tgctgtcgct cgtgctgccc agatttataa atttgacctt
    30421 ctaactggta tggttgggga atttgatgag ttgcagggca ttatggggga gaaatacgcc
    30481 cttttaactg gcgaagctgc tgctgtcgca acagcaattc gtgagcatta tttgccaaat
    30541 tcggcagaag gagagctgcc tgaaacaaag gttggtgctg tccttgctct tgctgataag
    30601 ctagacaccc tgctgtcctt tttctctgtt ggtttgatac cgtcaggctc aaatgaccct
    30661 tatgccctac gtcgtgcaac tcaggggatc gtccgaattc ttgagcattt cggctggagc
    30721 attcctatgg ataagctgat tgatagccta tatgagctgt catttgatag cttgacctat
    30781 cagcataagg ctgaggtgct ggactttatt tgtgcacgtg tggataaaat gatgggctca
    30841 gccattccaa aggatatacg tgaagcagtt ctggctagct caagctttgt tgtaccagaa
    30901 ctgttagcaa gagcggaggc tctggctgcg gcaagccagc tagacaccta caagcctgct
    30961 gtcgagtcgc tgtctcgcgt ctttaatcta gcgaaaaagg cagttgacgc tgtgctgatt
    31021 gatgctagcc tctttgaaaa tgactacgaa agggctttgg cacaggctgt tgattcacta
    31081 gtgctatctg gatcagccaa agaacagcta gctcaggtct ttgcccttag tccagttatt
    31141 gatgactttt ttgaccatac gatggtcatg acagaggacg aagctattag acgtaaccgt
    31201 ttagcgctgt tagcagagct ggttaaaaag gtagagacca ttgcggcctt tgaccgatta
    31261 aatactaaat aattcgctgt gtaagattaa gcacatcgcc ctgtgttagc tgttcgtatt
    31321 ccctagatga tataggtgac tgattacctg ccttgggata agtccttccc taagcactca
    31381 agacttatca agcaattgat acttagtcaa atcagtcctc ttgcttacta cgagatatcg
    31441 tcttgggcta gctttgctag caatagctgt gctggtcagt ggtcaataaa agcatcagga
    31501 acactgttag taaagtgagc atggatttta gcttttcaca agaagcttgc tacagccttc
    31561 ttggcagaag cataaggcta agcagctgct ggcacagcct tagatataga caaaaagagt
    31621 gcagtactct atgtcacaaa cgaaagagaa aggattagag gcagccccat ttgcaggcag
    31681 cccttgctgg cacagctggt gaaaaaggac ttgaaaggtc ctagtaacgg tcctaaagag
    31741 gctgtctagc ccatcatcaa gcctcatcag ctgctcactg cttttggtgc agcccttata
    31801 tgtgatttat ggatcctaaa aaaatcgctc gtattaacga gcttgcaaaa aagaaaaaaa
    31861 cagttggctt gactggtcct gaaaaggtag agcaggccaa gctgcgtgag gaatacattg
    31921 agggctatcg ccgctcagtg cgccatcaca ttgaaggcat taagattgtt gatgaagacg
    31981 gaaacgatgt tactcctgag aaattaagac aggtgcagcg cgaaaaaggt ctgcatggac
    32041 ggtcacttga tgatccggaa tcttgattat taaatgaata taaatatttt gccatgattt
    32101 aatgttacta atgagaaaaa gataaacaaa gacaaatagc tttaatcatt aggtctttcg
    32161 acaaaagagt cattattttt agaaatggtt aattgtgagg tactagccat ctgtctcatc
    32221 aatacagttt aggtagagat aataatatct ctacctattt taatgcgttt cattaaaaag
    32281 actgatagtt tataaatgcc attaaagaga taggcttaag actttgtcaa gctcaataag
    32341 ctaacctttc tggaaaaata atgacatttt tgtaagaaaa tattaaagaa agtatttaca
    32401 tatgtcttga attttaatat aatatagttg gtaagaattg aatggtcact ttaacaaggg
    32461 cgatacaaaa tagctagcct tgtgttgctg gatacctgct catgattgct tttgctatca
    32521 gttgagaggt attctcattt aactcttatc agtgttttgt tttaccgatc aggcgatata
    32581 aggaggtaag cattatgtta caatttgctt caaatatttt agctactagt gtagcagaaa
    32641 caactcaagt tgctcctggt ggttgctgct gttgctgttc ttgttgttgc tgcgtctcag
    32701 cttcatgggg caatactacc ataaacaaca attatggtgc agctgagcca aaagcgtaaa
    32761 ctttaatact tctatttaat agttaatagc taggtcacaa tcattagttt gctagcgact
    32821 aaggttacag tttgtaattg atggtgttag ctggtgttgg ataggggtgt tacatgacaa
    32881 gagacgaaga caatcagctt gatgtcaacg tcttgtagta attagcaggt actagtcggt
    32941 acctgctaat tactattatt tattaatata ttacaggaag acagttatgc catttttttc
    33001 taaggaaaaa caacgttcgg ataaccaaag tgacctaaca agagaagaag cacgacagtt
    33061 atttgaattt aataccaatc acttatcgtt atcaacctat catcatcaaa cggtattaaa
    33121 aacatcaaaa cagcttgtgg cacagcattt gatgcctgat gaaacagaca atcttagcca
    33181 acggtttttg atgaattaca aggctaataa caattaccta gggtttaaga ccagtgtggc
    33241 tgagtttttt acggattctg cagtgaccac cttttcaaat agtgactatt ttgaggatag
    33301 ggcaaacacg atagcacttc ctaaagctaa gaaggtctca gcagccctat caacctgtat
    33361 caccaaccgg agaagtcata ggcagtttat agatgaggag atgcctttgc aggatttggc
    33421 tgatttgctt tattatgctt gtggtgtcag ctctcaggca atcatcaaag aaggcatgac
    33481 taagacagta gccttaagaa attgtgcttc tggtgggggt ctgtacccca tcaccttatt
    33541 tttctatgca agaaacgtag aaacactcaa ggacggtttt tatgaatacc ttccttatca
    33601 gcacgcgctg aggtgtcatc atcttagtga tcaggaggat attagagcct ttgccgaata
    33661 cggaccgatc actgccgaaa actgcaatgt cattcttatc tatgtttatc agtacatcaa
    33721 aaacacacgt aaatatggaa atcaagctac tgcttatgcc tttattgaag ctggagagat
    33781 tgctcaaaat gttcaattgg tctcaacagc tttggtatat ggaagtgttg atattggagg
    33841 gtacaataag gaatacctcc aagaaaagct aggcttggat ggcttgaccc agcatgtgat
    33901 tcacatgacg attattggaa ataaggagtc tcaatgaaat atcaattaaa tagcaatgtt
    33961 cgcattgtgc aatttgacga tacgttttgc tttagaaaag gcctatggga ttttaatgaa
    34021 gctgttttag acattgcaca agagccacaa gccttaaaag aagcctacta cagtatcatc
    34081 tccgattggt ttaacgggaa agttattgat actgatacct acgaaaaaac actagagtct
    34141 gacttatttg caaaattgtc agaggtcatc acagccttgt attataacga cctattgatg
    34201 cttgaagacg cttatgctct tgaagaaaat atcatgaagg tcttaacagg caattatcat
    34261 ttcatagctg aatcaggaca ggctaaggat actgcacctg tcttatttat cagtgattca
    34321 agctatgtca atgaatctgc tgagctgctg gccaagcacc tgaacttaaa ccttcaggtg
    34381 gctagcgatg agctaaaaat gctcattcaa gaaacagatg ttacctctcg cttagatgct
    34441 ctggagcacc atcgcaacat gaagtgctta tctgagaagc tcgcagacta tcagagtatt
    34501 gttatttgtc aaggccggtt gaatattatg atgctgcgtc accttaatga aatcagtgtg
    34561 gccttgaaaa aacaattggt gcttggcttt gttgatgggc cgtttatcca tgcttgtacc
    34621 ttaaatcctc ctcatagtgc tgattttgat agcttggaga gaagggtgct ggcacgttta
    34681 caggatcaca cgctttatca gcgctttgca agtcagcagt tgccgccaac acagcctgtt
    34741 agctcctctt atgtaccttt gttaaatgtg ttaatgaatc tggttgtcag tgaggccttt
    34801 attattgctc aaacaggaag ctcaaaattt gaagggcgtt tgttaagtgt ctatttgcca
    34861 acgcttgaga ttcaggtgca ggatattttg aaaatgtcta attctcagac acaaggggct
    34921 ctgacaaaat taaggtatga ggatcaacag atttcaacac gtgagattgt taaaaaactc
    34981 cttcaagaag agtcataagg aggtctaagg atgctacatt attacccttc gttcaaccat
    35041 attcttgata agctaaaggg ccttagtggt aaccgaactg gtatcttaaa tcaatctcag
    35101 gttcctattt gtaaccatcc tcatgatgtt tacttaaaga gtgtgacagg acagatgcct
    35161 gactaccaca agcaatttat tggtgagctg agtcaggtga gctatcatat cattggttat
    35221 ggcagtcatt atgaggaagc cttgatcaaa tacttaggtg aaagcattga gcgttatgcc
    35281 actgttattg ctggggaatt attatcagac cggattgttt atgcttctta taaggaattg
    35341 agccagacgg atcctgtcat gcccttagag tatttgcagg tttttacgca ggaacaaatt
    35401 gaccgttgcc atgatttgca catgatcatg tgtgataaaa tggtgacgca agacgatgtc
    35461 ttgggctggg ttaagtgtcc gatgtttttt gaagataagg agatgtatgt gcctgcccaa
    35521 atgctttgcg ttggctataa gaccaatcag gctgtaggcg aaaagcacat cattccaggc
    35581 ttttcaacgg ggacagcctc tcatacaacg ctggaagcag ccatgtgtaa tagcttgatt
    35641 gagtatattc aaatcgactc tatgatgctt agctggcata ctaaaaagcc ttgtcccaga
    35701 gtgattattg atgatccgga aattctagct cttttggaag aggctagact tggtaaggac
    35761 agtctttatg agattatccc tattgacatg actgttggag aagataatcc gctttatacc
    35821 tttggtatta tccttaaaaa caagtccaat gaaggtcctt atctcttatt tggggttcag
    35881 gcgggcttgg atcctaagca taccctgtta agaggaatca tggaagcttc agctattagc
    35941 tatagctatt actataattt gttttataat ccaacgtcaa cacaaaatgc tgagagtgac
    36001 tctcccttgt ttttagacct agatagtaac gtcttttact atgctcatcc aaaggatcag
    36061 gagcttaaat ggaaggcctt tgagcccttg atttcaggag aggttcgtct tagtgacctg
    36121 acaaaccatg ctgggaaaga taaaaaagag gatttaaaga cactactagc ctacactaaa
    36181 aaagtaagtc ctaatgctgt ctttttagac attactcctc ctgaggcctc agaaaaaggc
    36241 tggtacgtga cacgtgtcct cactcctgag cttcttgaga tgtgcattcc tgcctttcca
    36301 tttgctaatc atccacgcat gagacagttt ggaggtgtga caaatgcctt tgtacaccca
    36361 atgccttaac ctatgctttt taatggctac cttttgtcct tcgatcgcaa tgcaggctat
    36421 ttttggccag ggtcgtgata gctatagctt taatctaata ggttttttaa gagctgtact
    36481 ggtttattat gccctagtct taacagggat ttacctgctg tcacctccta ttaaagcgcc
    36541 cttaggtcat agtgatggtc gtcttttgat cattggtttt atcttgagct ttgttgtgct
    36601 ctttgttgag gttgcttttt tacatcttag ccgctgctgg caaaaaaaag agtggcttcc
    36661 cttagtccta tcatttgtcg gaacgacaca aaaatggcca cagataggct atcccttggt
    36721 tttggcctgc tgtgaggaaa tcacctatcg tttgatttgg tttaacatct tgtggcttca
    36781 atggcgattg ccaattgctc ttgtcttgtt gatcaccagc ctgtgctatg ccctaaacca
    36841 tttcctgatg ggcagatcca ttttttacgc caaaatactg actggtctta tttacggaag
    36901 tatttattat gttagtcaga gcttatggct ggtgttgctt gttcatgttg gaggcaattt
    36961 atgggttgaa ggcttgagtc atcttcaatc aatgcataag aaggtggtac gatgatcata
    37021 atactagcat tgctatcctt tttaatccta gtgacccttt ttctaacaag tcataaaaga
    37081 cggcgcttag tcagatggca tttaaggcac atcagggcaa tgtcctatca gcaatggctt
    37141 gatctattgc ttggtctaat ccagcttggt ctagtgcttg tttgtctatt attttctgat
    37201 gctttagctc ttgatggttt gctgaccttt ttgggtcgcg tatcctttgg ctgggaaatc
    37261 atttgttatg tgctattgta tagcatagcc ttggtagagc tgaccctgtt ggttttggtc
    37321 ttgctttttg atcttatgct gaaaaaggac agtcgcctgc tcttaggaaa aatgacttgg
    37381 ctagccttta aaccagatag ggcagcagct agctttcttt tgttaagtct tgtcacactg
    37441 gttgatgctt tttgttactt aggtctatgt ctctttttag gaaaagattc agtggcaggt
    37501 cttacgcttg tggttttggg ctatgccttg gtcaaggcct gtcgttactc aggctggcta
    37561 cagcagctac tagccctatg cctctttagt gtgattggtg tctggtgtgt gacagcagcc
    37621 ttattatatg gttggttgat tggttcgctt ttattgacct taacttatct gttaattagt
    37681 tttaaagagc agcgttagag ttggaaagaa ggaataatat atgagttttg tagagttaaa
    37741 agatgttgtc aaggtctatc gaggcggcaa aaaggcaata gatcatgtct cactgacaat
    37801 tgaggaaggg agaatctacg gccttttagg gcctaatggc gctggtaagt caaccttaat
    37861 caatgctatt ttagggttaa tccctttgaa tgctggcgaa gtgactgttt tacagcaatc
    37921 ttataaatct attcgaaaaa ttagttccaa gattggctat gtccctcagg atattgctgt
    37981 ttatcctgat ttaacagcct atgagaatgt tgagcttttc ggctctctct atggcttaaa
    38041 gggaagtgag ctcaaggagc aggttttaaa aagcttggag ttcgtagggt taaaatcaca
    38101 ggcaagccag tttccaagcc agttttcagg aggtatgaaa agacggttaa acattgcctg
    38161 tgctttggtg cattctccta agctaatcat ctttgatgag ccgacggtag ggattgaccc
    38221 acagtctcgt aatcatattt tagagtctat tcgcttgtta aatgagcaag gagctactgt
    38281 tatttacacg acccactaca tggaagaggt tgaggcctta tgtgattaca tttacattat
    38341 ggatcatggt caggtgattg aagagggcag tcaggccgag ctagaaagac gctatgagtc
    38401 tgatttcaca aagcaaatca tggtgacagt cgcagctgac caagcaatcg atctctctaa
    38461 taagcccaat tggagactga tggataacga gcttgaagca gttctcctga ttgaacatga
    38521 agacattggc tcggttgttc gtcagctgac agatgctcat attgctttta gtgagattag
    38581 gcataagcat ttgaatttag aagaaatctt cctgcatttg actggtaaga agctaagaga
    38641 ttaggggttg ttatgatctt atttcattta atcaaaaaag aaagcttaca gatttttagg
    38701 gatcggactg ctttgttgat gatggtggtt tttcctatct tgatgattct gattttaagc
    38761 tttgctttta agtccagctt taatacagca gctactgttc ctaaattgac ggttcgttat
    38821 cagcttgagg gcaaggaaac agagtatcaa aagaacttta tcacgttttt aaagctgtta
    38881 aataaagagc ttcatttaga agctaaagaa accaaggata tcgctaaggc taagcaaaag
    38941 gtcagcgagg gcgccttgac ggcagctcta gaggttaaga gcgaccaaaa cattgaggtg
    39001 accaccaaca gcattaacca acagaatgct gatttgatta atatgcttgt caatatctat
    39061 gtggataacg ccaagaccta tgattcgatt gctaaccttt atccagaagc cattagcaac
    39121 atcaagaaaa gaaaaataga ctatatcgcc tctagctctg tgcaaaccag taaaggcatg
    39181 agctcagcgg attactatgc tatttccatg tttaccatga ttacctttta tagcattatg
    39241 tcagcgatga atctggtgct atcagatcgt cagcaagggg tggctagccg catttatttg
    39301 acaggggtct caaatagtgc tattttgctt ggaaaattaa ttggtggtat gctagcaaca
    39361 gcagtccagc taaccattct ttatgtcttt acccgatttg tgttacgtgt taattggggg
    39421 actaatgact ggcagattat cggtgtgacg gcctcgctag tttatttgtc tgttgccatc
    39481 ggtatcgggc ttgcgactgg tattagaaat caatcctttt tgacggtagc gtctaatgca
    39541 gtcattcctg tctttgcctt tttgggagga agctatattc ctttgtcaac cttaaatagc
    39601 gccttgatta atcagctgtc taatatttcc ccgataaaat gggtcaatga tagtttgttt
    39661 tatcttattt ttggtgggca gtccaatccc ataccggtta ccttaatggt taatcttggt
    39721 ataggaacag cctttatcct ctttgctttg gtcagaatga gaaagcaggt ggcagcatga
    39781 ttccttttat taaagcctta tttatcaaaa ttagacgtaa aaaaacaagc tatatcacct
    39841 ttatcctgtt gcctatgcta acaacaatgc tggccttgtc cttgagcttt acagggggaa
    39901 gtcaagctaa gattgggatc ttagataagg ataagagtca ggtttccaag cagtttgtgt
    39961 cgcaattaaa gcacaataaa aaatatcaga tatatactag gctagaggaa aaggctattg
    40021 atcaatacct aaaggccaag acactggagg ctgtgctgac cattgagccg ggctttggtg
    40081 agaaggttct aaaaggagac actcaaaaga tcgctctacg ttcgattgct gatagtcaaa
    40141 taacagaatg gtttaaggcg caggctaatt atctcttgga gaattacaat atcattggtg
    40201 atgcggcagc aggcaatcaa gaggttttca agaagatttc agctcataac acgaagctat
    40261 cctacaaggt caaagaaatc accctagctg atcgttccca aagtaagtct gtttcctcga
    40321 caacaactgg ctttttattg atcctaatgc taggcagcac cagtgtcttg tacggtggta
    40381 tcttgcttga taagtccagt caaatctaca atcgcttagt cttatcaagg ctatcaagcc
    40441 ttcaatacat gctgagctat gtctgtgttg gtattgttgc ctttgcgata caaatagtga
    40501 ttatgctggg attactcagg gtagcaaatg tcagctttta cattccaaca gccattgttt
    40561 tgttgacttt ctttctttat agtttgttag ctataggctt tggcttaatg attggtgcgg
    40621 tttctaaaaa tgcgcaacaa agcagtcaat tggctaatct gattgtgatg ccaacctcta
    40681 tgctggcggg ttgtttgtgg ccgcttagta ttacgccgcc ttatatgcag gcgattggaa
    40741 agctactccc acaacattgg gtgttaacca tcatcagcac tttccaaaat ggcggtaatc
    40801 taggtgaggc ttggccttat ttcttggcct tgtttgtagc agccatgacc ttaatggtac
    40861 tagcaagcgt gctgatgaag cctttacatc gctagactaa gttgtcttac cctttttgaa
    40921 ccaagcttaa aaagccttat cgttccattt atggcgcgat aaggcttttg tgttgtatta
    40981 gactagatac tgatcaacta aacgactata gataatcttt tagtgtctta gtcttttctt
    41041 ttgcgtcttg ttaggaagcc taatccgaga agagagagta agcctgttcc aagtcctgtc
    41101 attagactgc ctgcttcatt tgttcttggt agtcccttgc cgctagactg gctagtagtg
    41161 tttgatggct tggttggttt ttgaggctta acctctggtt gaggcgctgg tttaggctga
    41221 ggttccggtt taggcttagg ttctggcata ggctcaggtt gtggcttagg ctctggctta
    41281 ggcattggtt ctggctgagg ttccggttta ggctcaggtt gtggcttagg ctcaggatct
    41341 ggcataggct caggatctgg cttaggcaca ggttgtggtt taggctctgg cttaggctca
    41401 ggttgtggtt taggctctgg cttaggctca ggttgtggtt taggctctgg cttaggctga
    41461 ggatctggct taggttctgg cataggctca ggttgtggct taggctctgg cttaggcatt
    41521 ggttccggct taggctctgg tttaggctcg ggctttttag gagctcctgc ctcaccgctt
    41581 tctccttctg gatatttagt ttgaccattt tcacctggta aatgatgtgg attgttccca
    41641 cctggtggtt taggtcctgg atttgggttc ggaagttttg gtgttaaagt ggaaccaaga
    41701 agatgttgat aaaatttacc tgtactataa ttatatgatg aagttacata aagatttaag
    41761 ctataggtat gtgctgtagt ttggaagttt ttttcagcag tttcaattaa cttttttaat
    41821 tctgaatctt catctttgtt tagatgataa ccatctttga aatgatttgt agcgtatcca
    41881 tcagtaaagt gccaaatagc tagctgtgtt aatcggcgac tttgatcttc acttaaatta
    41941 cctaatgtct tattaggata gccatttgaa agaacagtaa ctaattttga agttaagtta
    42001 tcactgggct tctgagattt agctcttaaa aggctttcat ctccttcttt cttttcatag
    42061 atagggagtt ttatacctag cttacttgga tctttaaatt gagattccca gagctcaggt
    42121 gaactattta acctgttaaa gcaatagaca cagtgctctt tatcggtttt tctttcgggg
    42181 tgatttgttg gtgttacata taaaaatact ggccagtctc caccgtcttt tgttccatca
    42241 tcatagccat agtactgctc tgccagtact cttgccgcgc ctccgataaa gctgcccgac
    42301 atgatgatgc agactgtcga ggctgctagc atcttcttca ttgtttttct catgtttctc
    42361 tcctttgagt ttagaaatag tcattcccaa acctttcttc tccgtagaat agcttaa
//
LOCUS       DARYLD010000011        42298 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYLD010000011 DARYLD010000000
VERSION     DARYLD010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42298
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..313)
                     /locus_tag="TU651_000503"
     CDS             complement(<1..313)
                     /locus_tag="TU651_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0896530.1"
                     /translation="MDVKIQDIRKSYKDRDILKGVSFEIQKGTICGLLGINGAGKSTL
                     MKIIFGLEKADSGNVIFYNQKDQHVNYEIGALIESPAIYMNLSAFDNLKTRALLYNIS
                     GE"
     gene            complement(797..2149)
                     /locus_tag="TU651_000504"
     CDS             complement(797..2149)
                     /locus_tag="TU651_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0896531.1"
                     /translation="MTKTYSIRYRVGITVGEILIGIAILVISLLIIPYLLVFTKQLNI
                     HGTSFDIVLGDKVSTEEITKQMDTLTFDYVLFNRKNGEVLNGNYQKTELSYYETVFED
                     KKPINVGTIDYKAYSNDQILLVVRQPTLPEFVNPSLRKVSFNTLSIILFIVGTLSIVF
                     ISVTKLLREFAHDFRLIQKISLNMGSRDYKIERSTTKISEFNDILAMLYQKDDELTIL
                     LEAERAEKKDLSFQVAALSHDIRTPLTVLKGNLELLEMTDLSNQQISFIGSINHSVSV
                     FEKYFNSMITYSRLLIEERDYQEVIEVTEFMSGLQIEIQEIMHTEQVDFDMKNNLRIT
                     HFKGNRFNLERALINILVNAAQHATDVKQVSLTAKEEQDQLIFEIWNSGSKFSKQALN
                     GANKLFFTEDNGRSSKHYGIGLSFAQGVAVRHQGKLQLLNPLKGAQVNLIIRKYELLL
                     "
     gene            complement(2142..2825)
                     /locus_tag="TU651_000505"
     CDS             complement(2142..2825)
                     /locus_tag="TU651_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0896532.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGLNLGGDDYLPKP
                     FSVNQLIAKVSAHLKREERVKHGENVEKITRELLPITFYLQEKMLCVSGKPVPLTSRE
                     YHILELLSSHPNKVFTREDIYEHVYDDEANALFRSISEYVYQIRIKFAPFNLNPIKTV
                     RGVGYKWYD"
     gene            complement(2862..4238)
                     /locus_tag="TU651_000506"
     CDS             complement(2862..4238)
                     /locus_tag="TU651_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0896533.1"
                     /translation="MLTMKHKMLIFCLLLSIFVSQFHMLHVYAETSSKTQYNILIKES
                     LDTNKVKKQLNDQGMIVLDEIPEINVLTIAAANDSSMILEKNCNYIDDISRNNTFTVN
                     PKMTYQFGHAFYLDSDLNYWNKQWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNT
                     DISSKIISVQNFTEDPVTKAIDVNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMY
                     KVFEEGNAQDEWILKAIIQAAKDDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAI
                     NYAHKQGSVVVASVGDEGANLNNQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVT
                     VGSVDGDGAISNFSNRGRNVVDIFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLE
                     GKYTYGYGTSIAAPKVAAALGLIIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLL
                     NITDFISK"
     gene            complement(4406..4537)
                     /locus_tag="TU651_000507"
     CDS             complement(4406..4537)
                     /locus_tag="TU651_000507"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896534.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(5646..7592)
                     /gene="thrS"
                     /locus_tag="TU651_000508"
     CDS             complement(5646..7592)
                     /gene="thrS"
                     /locus_tag="TU651_000508"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL0896535.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(8183..9517)
                     /locus_tag="TU651_000509"
     CDS             complement(8183..9517)
                     /locus_tag="TU651_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL0896536.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(9519..10517)
                     /locus_tag="TU651_000510"
     CDS             complement(9519..10517)
                     /locus_tag="TU651_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0896537.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(10813..12288)
                     /locus_tag="TU651_000511"
     CDS             complement(10813..12288)
                     /locus_tag="TU651_000511"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0896538.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(12358..13359)
                     /gene="ccpA"
                     /locus_tag="TU651_000512"
     CDS             complement(12358..13359)
                     /gene="ccpA"
                     /locus_tag="TU651_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL0896539.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            13533..14618
                     /locus_tag="TU651_000513"
     CDS             13533..14618
                     /locus_tag="TU651_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0896540.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSVLPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(14792..16375)
                     /locus_tag="TU651_000514"
     CDS             complement(14792..16375)
                     /locus_tag="TU651_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896541.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            16613..17464
                     /locus_tag="TU651_000515"
     CDS             16613..17464
                     /locus_tag="TU651_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0896542.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            17725..18393
                     /locus_tag="TU651_000516"
     CDS             17725..18393
                     /locus_tag="TU651_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL0896543.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            18508..19434
                     /locus_tag="TU651_000517"
     CDS             18508..19434
                     /locus_tag="TU651_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL0896544.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(19418..19606)
                     /locus_tag="TU651_000518"
     CDS             complement(19418..19606)
                     /locus_tag="TU651_000518"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896545.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(19718..20185)
                     /gene="smpB"
                     /locus_tag="TU651_000519"
     CDS             complement(19718..20185)
                     /gene="smpB"
                     /locus_tag="TU651_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL0896546.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(20188..22512)
                     /gene="rnr"
                     /locus_tag="TU651_000520"
     CDS             complement(20188..22512)
                     /gene="rnr"
                     /locus_tag="TU651_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL0896547.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(22599..22835)
                     /gene="secG"
                     /locus_tag="TU651_000521"
     CDS             complement(22599..22835)
                     /gene="secG"
                     /locus_tag="TU651_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL0896548.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(22881..23027)
                     /gene="rpmG"
                     /locus_tag="TU651_000522"
     CDS             complement(22881..23027)
                     /gene="rpmG"
                     /locus_tag="TU651_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0896549.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            23515..25401
                     /locus_tag="TU651_000523"
     CDS             23515..25401
                     /locus_tag="TU651_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0896550.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQG
                     ERGEQGPQGERGEQGPRGENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQ
                     PEVKPQPETKPQQPNKPSTITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKR
                     KRKQ"
     gene            25715..26755
                     /locus_tag="TU651_000524"
                     /pseudo
     CDS             25715..26755
                     /locus_tag="TU651_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            complement(26918..27511)
                     /locus_tag="TU651_000525"
     CDS             complement(26918..27511)
                     /locus_tag="TU651_000525"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL0896551.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(27508..28329)
                     /gene="mutM"
                     /locus_tag="TU651_000526"
     CDS             complement(27508..28329)
                     /gene="mutM"
                     /locus_tag="TU651_000526"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL0896552.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(28744..30543)
                     /locus_tag="TU651_000527"
     CDS             complement(28744..30543)
                     /locus_tag="TU651_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0896553.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(30704..35344)
                     /locus_tag="TU651_000528"
     CDS             complement(30704..35344)
                     /locus_tag="TU651_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL0896554.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(35517..36864)
                     /locus_tag="TU651_000529"
                     /pseudo
     CDS             complement(35517..36864)
                     /locus_tag="TU651_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(36929..38245)
                     /locus_tag="TU651_000530"
     CDS             complement(36929..38245)
                     /locus_tag="TU651_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0896555.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(38238..38570)
                     /locus_tag="TU651_000531"
     CDS             complement(38238..38570)
                     /locus_tag="TU651_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0896556.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(38580..38897)
                     /locus_tag="TU651_000532"
     CDS             complement(38580..38897)
                     /locus_tag="TU651_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0896557.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(38921..39820)
                     /locus_tag="TU651_000533"
     CDS             complement(38921..39820)
                     /locus_tag="TU651_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL0896558.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            40000..41202
                     /locus_tag="TU651_000534"
     CDS             40000..41202
                     /locus_tag="TU651_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL0896559.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(41365..41841)
                     /locus_tag="TU651_000535"
     CDS             complement(41365..41841)
                     /locus_tag="TU651_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0896560.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(41986..42195)
                     /locus_tag="TU651_000536"
     CDS             complement(41986..42195)
                     /locus_tag="TU651_000536"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896561.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
BASE COUNT        12895 a         9929 c         7708 g        11766 t
ORIGIN      
        1 tttcaccaga aatgttatat aagagtgctc tggtttttaa gttatcaaaa gctgacaaat
       61 tcatatatat cgctggagat tcaattaatg caccgatctc atagttcaca tgctgatcct
      121 tttggttata aaaaatcaca tttccactat ccgctttttc taaaccgaaa ataattttca
      181 ttagcgttga tttcccagca ccgttgatac caagcagtcc acatatagtg cctttctgta
      241 tctcaaatga aactcctttt aaaatgtctc tatctttata agatttccta atatcctgaa
      301 tttttacatc catgattaca cctccttttt tatttaatca tacggtttct ttttcaatat
      361 ttgttcagaa aataatgaaa gcatcaagat ttggaataaa aagaaaatca aacattttta
      421 tagaagcaag caaccaaatg ttcttacaac gtgaatatgg aacctatctt tgtccggtta
      481 aagacttatt tgggctacaa acgttgcata accttcatta tgactaaaag ctataatgtc
      541 agtaaaataa tattcagttg attcttgagt atttaagaat atgaaggcca gcgagttcag
      601 aatatgaaaa aagcccgttg aacgggcgat aatcaagtaa acactgttca gtgattgtct
      661 ttaggctcgg ctgaggagat caacctacag aagccaaggc acttgttttt gaagcaatct
      721 ccaaaaagtt agacagaaac tctaacgaat ggaagtacag ctcatctaac gggtggtcat
      781 gatttaacta tctactttac aggaggagct catactttct aatgattaaa ttaacctggg
      841 cacccttgag tggatttaat aattgtaact taccctgatg ccttacagcg acaccttgag
      901 caaaagataa accaatccca taatgcttgc tgcttctacc attatcctca gtaaagaata
      961 atttattagc accatttaat gcttgttttg aaaacttcga accactattc cagatttcaa
     1021 aaattagctg atcttgttct tcttttgcag ttaagctaac ttgcttcaca tcagtagcat
     1081 gctgtgcagc attaactaaa atattaatga gagctctttc taaattgaat cgattacctt
     1141 taaaatgagt gattctaaga ttgttcttca tgtcaaaatc aacctgttca gtatgcataa
     1201 tttcctgaat ttcaatctgc aaaccgctca taaattctgt tacctctata acttcctgat
     1261 aatctctctc ttctattaac aagcgagaat aggttatcat tgaattaaaa tatttctcga
     1321 atactgaaac actatgatta atagaaccaa taaagcttat ctgttgatta gaaagatctg
     1381 tcatttcaag taattctaaa tttcctttta aaaccgttaa aggtgtcctt atatcgtgtg
     1441 aaagagccgc tacttgaaaa gagagatcct tcttttcagc tctttcagct tctaacaata
     1501 tcgtcagttc atcatccttt tgatagagca tagctaatat atcattaaat tcacttattt
     1561 ttgttgttga gcgttcaatt ttataatcac gactccccat atttaaagaa attttttgaa
     1621 ttaaacggaa atcatgagca aactctctca atagctttgt gacagagata aatacaatag
     1681 atagtgtccc tacgataaac aggataatag ataaggtatt aaaggaaact tttcgaaggg
     1741 agggattaac aaactctggg agtgttggtt gtctcacaac caataatatt tggtcattac
     1801 tataagcttt atagtcaatt gtacccacat taattggctt tttatcctca aaaactgtct
     1861 cgtaataact taattccgtt ttttgatagt tcccattaag aacttcacca ttctttcgat
     1921 taaaaaggac gtaatcaaac gtaagtgtat ccatctgttt agtgatttct tctgttgaaa
     1981 ccttatcacc taaaacgata tcaaaacttg tcccatgaat atttaactgt ttagtaaaca
     2041 ctaacaaata gggaatgata agaagagata taactaaaat tgctatccct attaaaatct
     2101 cgccaactgt tattcctact ctatacctta ttgagtatgt tttagtcata ccacttatac
     2161 cccactccac gaactgtctt aataggattc aagttaaaag gagcaaattt tatacgaatc
     2221 tgataaacat actctgaaat agagcgaaat agagcatttg cttcatcatc atagacatgc
     2281 tcatagatat cttcacgagt gaataccttg ttaggatgac ttgaaagcaa ctctaaaata
     2341 tgatactctc gactcgttaa tggtactggt tttccactaa cacaaagcat tttttcttgt
     2401 aaataaaagg tgattggtaa taattctctt gttatctttt cgacattttc cccatgcttt
     2461 actcgctctt cacgtttcag atgagcactc accttagcta taagctgatt cacactaaaa
     2521 ggcttcggga ggtaatcatc tccaccaagg tttaatcctt taataatatc gtcttcagta
     2581 tctttagcac taacaaagat aataggagaa gcaactttat ctcggattaa ttgacaaatt
     2641 tgtgtacctt caacattagg catcatgaca tctaataaaa tcaagtcaaa cccttgaaaa
     2701 tctctaaaat tgattggaaa agtcacttct tgataggttg ttaccttgta atttttcatc
     2761 tcaagaatgg tccgcataag ttttaaaatc tcataatcat catcaacaac tagaatctta
     2821 tacatagtct tacctcataa tagttacact gttattttac actattttga gataaaatct
     2881 gtaatattta acaatctaat tggttttcca ttatcatcca agctactcca agagttacta
     2941 tacaaaatag ttatggcctc atctggttta tcttttaaat catatttttc gatgattaaa
     3001 cctaaggcag cagctacttt aggggctgca atagaggtcc cgtagccata agtatatttc
     3061 ccttctagtg ttgggataat aacccaatct tgctcaaata atttattgtt aatccaagtg
     3121 tcatagccat gaagcgctag cttcttgctt cctccacctg ccgcaaagat atcaacgaca
     3181 ttccttccac gattggaaaa gttagatatt gcaccatcac catcaacaga tcctactgtc
     3241 acaacattat ctagctgtgc gggaatatcc tctattgtcc catcgactga actaaacgct
     3301 cttcctgtga gagcactgac taagttctta agctcagctt gattatttaa gttagctccc
     3361 tcatcaccaa cagaagcaac taccactgag ccttgtttgt gtgcataatt gattgcccgt
     3421 tgatagctat tgattagagc agttctatct tcatcaatat ttgatgaagc ctttaataaa
     3481 tactgaccaa gactcaaatt tatgacatca acatcatcct ttgctgcttg aataattgct
     3541 tttaaaatcc attcatcttg agcgtttccc tcttcaaaca ccttatacat tctaaccttc
     3601 atgcctggag caattcctgt ataataacca tttgaagaca tttgtccaac aacagatgta
     3661 ccatgacctg ttttatccaa aacattatta acatcaattg ccttagttac tggatcctcc
     3721 gtaaaatttt gaacagaaat gatctttgaa gaaatgtcag tattattatc agtaatacca
     3781 gaatctatta caccaatggt tacctcacct gatgacttat gccaaaacct actactagta
     3841 ctaatacttc tttgcatatc ccattgttta ttccagtaat ttaaatcact atctaaataa
     3901 aatgcatgcc caaactgata tgtcattttg ggatttactg taaaagtatt attccttgaa
     3961 atgtcatcaa tatagttaca attcttttcc aaaatcatag atgagtcatt tgcagcagcg
     4021 attgtcaaaa cattaatttc aggaatttca tcaagcacta tcattccctg atcatttaat
     4081 tgctttttta ccttattggt atctaagctt tcttttataa gaatattata ttgagttttg
     4141 ctactagtct cagcatagac atgtaacata tgaaattgag atacaaaaat agacagtagc
     4201 aaacagaaaa tcaacatttt atgcttcatg gtcagcactc ctttaagtat tgtttttaca
     4261 cttatcgtat gactaacatt tcagatttgt ttcagattct agaaaataat acttactatt
     4321 gtgcttattt aagtccaaaa attagcatta cactcattaa gtatctgaga ttaatctagc
     4381 taacattcta aattgttttc tcccactaat cttttgttct taattccgac ttataattaa
     4441 agacaaaagc taatttttct aactgcctcg catagcactc atacttgcca atcattgttg
     4501 tcatcgtctc ctgattgagc ttagtttctt cttccacctg ctccagttta ctagctgata
     4561 tgcaagtgca atggtcgttt tttgtgaatc acacctactt tgaatctggt aaaatcattc
     4621 tactaacaaa cttcctgtgt aatttctagt agcctaggta gcctgataaa gagatttctt
     4681 caaataaaaa taaccatgtc gaatgccagc gctccatttc ttaccagcat tttcattatt
     4741 ccccagctaa agctctatcc atgaggctaa gtgacctgtg cttagaatta actcatatcc
     4801 acactagtct cagaaataaa gactgaagct atcatgatgt cactactagg aatgaatgaa
     4861 atctagggtt tctacttgac agtcatagtg agacaaacaa gcggcaattt gctcttctaa
     4921 actcccgatt tgtttctaat agcaagcata aatctccata gactaccccc atagaaaatg
     4981 gtggtgattg gagaaatcac cattaagtgc ttcacgacgt tgaggagctt tcttcttcaa
     5041 actagtataa acaattaatg gactacttac tctagctgtc ataggcgttt gagcaatcag
     5101 tagttgaaat agcttgcaac cgaaagcacc cagcatactc tcaatgcgga tcggaagttc
     5161 aatgccacct aactgtagaa ttttataatg caaattgtcc tttattaaga accttattga
     5221 tcattttaag ctttagttcg ggagaggaac gaatcttttt ccttagcagc tttacaatca
     5281 attaatcgtg ctaaatactt taaatggaat tgattgatat caaattgttt gaatgaataa
     5341 ctctggtttt gtaggccgca gatttctacc ttgtcttgat gtcttaatgt catgttaaaa
     5401 gcaccccatt cgttagatag tttgtctaac ttttggggcg cagttcattc attagatttt
     5461 ttatctaatt tttgagaagc agtttacttc tgatgagggc ttctatattg ctttcattag
     5521 ttctatgagt gagagcaaag ctcttgtagc tatttgtccc agattttttt atgtcatctg
     5581 ttttgcaagt caagctgacg tctgcttaat cagcctatct aaaaccagct tgcttggtct
     5641 gctttttagc cttcagctgg gcgtgatttg cgggcaatat cagccaaaat gttatcaaca
     5701 aatgctgaaa tagcttcggt atgtgttgcc ttactgccat agcggcgcac attaactgac
     5761 ttgtcctgca tctccttatc accaacgatt aattggtaag ggattttact ggtttgagag
     5821 gcacgaatct tatattgcat tttctcatta cgatcatcca catctgcacg aatcccatga
     5881 tcacgaagga ttttagcaac ctcccaagca tagtcaatat gggcctcatt ggaaattggg
     5941 ataactgtta cctgacgtgg tgccagccat gttgggaaag ctcccttata ggtttcaatc
     6001 aaaatagcag taaagcgctc catggttgaa atcaccccgc ggtggatcat caccggacgg
     6061 tgttcttctc catcagcacc aatatagctc agattaaaac gctcaggcag taagaagtcc
     6121 agctgaatgg ttgatagggt ttcttcattt ccaagggctg ttttgacctg aatatcaagc
     6181 tttggcccgt aaaaggcagc ctctccttct gcttcaaagt aatcagcgcc catttcatca
     6241 agcgcagcct tcagcatgct ttgagcattt tcccacatct catcgttatc gtaatattta
     6301 tgtgtatcct ttggatcacg ataggacaga cggaagcggt aatctgttag gttaaaatcc
     6361 tcataaacgt caataatcag ctgaagagct cgctggaatt cctcctgaat ctgctctggc
     6421 gtcacaaaca ggtgcccatc gtttaaggtc atctcccgca cgcgctgaag ccctgaaaga
     6481 gcccctgatt tttcatagcg gtgcatcata ccaagctctg caatacgaat cggcagctcg
     6541 cgataggaat gcacatggtt tttataaacc tgaatatggt gtgggcaatt cattggacga
     6601 aggacaaatt cttcaccatc tcccatatcc attgtcggga acatatcctc ctgataatgc
     6661 tcccagtggc ctgatgtttt ataaagctca actgaagcaa gcggcggagt ataaacatgc
     6721 tgatagcctg atgccagctc tttatcagtg atatagcgct caagcgtgcg acgaatcgtc
     6781 gctccatttg gtagccaaaa tggcaagcct tgtcctacct cctgagagat cataaacaaa
     6841 tcaagctcct tgcctagctt acggtgatcg cgctccttag cctcctcaag gcgtgtcaaa
     6901 taggccttga ggtccttttt atcaaaccag gctgtcccat agacacgctg catcatgtta
     6961 ttatcgctat tgccacgcca gtaagctcca gctacattta acaaatgaaa gacccgaatc
     7021 cgacctgttg acggcacatg aggaccacga caaaggtcca caaattcacc ctgacggtaa
     7081 acagttaagc cagccgcatc atctgcatgc tcattaatca actcaacctt ataagggtca
     7141 tccttaaaaa gctcaagagc ctcttctttt gtgatctcct cacgaataca tggaaagttc
     7201 tctttgacaa tttttttcat ttcctcttca atgcgaggca ggtcttcgtt agagatttga
     7261 ccatcagcat tatctgtatc ataataaaaa ccatctgcaa tggcagggcc tacaccaaga
     7321 tgcagcttgg ggaacaagcg cttagcagct tgagcaaaca agtgagccgc agaatgacgc
     7381 agcacctcaa aagcgtcctc atgatcagca gttataattt ctatactacc gtcctcttca
     7441 atggcgcgcg tggtatcaat taattgacca ttaaacttac cagccaaggc ctttttagct
     7501 agagatttgc tgatagagtc agcaatctca aaggttgtga caccagattc aaattcacgc
     7561 accgcgccgt ctgggaaagt gattgtaatc atctgttttc tcctataaac catctagata
     7621 cttaaaacaa gctaatcaag cagggctata tctcccaagc cttctgctgc tacgacaaaa
     7681 taaaaactga ctgcctccca aaggacgcaa tcagcgtggt tccaccttta tttatgcatg
     7741 acaaagaaat cctgtcctgc acctcagctt ggctatatcg tgaccaccgt tttatgtttg
     7801 cataaaagca aggaaggagt attacactag acaccctgtg ctcttctcac caaccagcac
     7861 tcgcttaaag gatgcgacct aatctaactt gtcttcctga ttattatagc aatatttgga
     7921 aataattcaa gtgatttttc ctaaaaaagc tgagataagc ccacagacct ccaagcccac
     7981 aaggcaagaa tgactaggca aggaaccctg aaacttctgc cacaagcctt tgaagaacag
     8041 ctcaaacagg acttgccgcc tgtcgtctca gttcacaaga caacaaacta aatcctttag
     8101 acaaatgatt atcctaaaga gctatctgct ctctcacgca gaaccaaagc ctgtaattgc
     8161 aggcttcttt gtttatttag ccttagtcca aaaagtctcg gatcgcattg accagcttga
     8221 taggggcttt gagcaccttg acagatgtca gtgcagttgc cttagctgct cgcttaggca
     8281 agtgaatcgc tccttgaacc agcttgattg agccactctt ttctgttcga ttgagataga
     8341 gacttagctt tttcgtctct ttattgtgtc gcgaaatcaa ggtatctaaa taaaaggtgt
     8401 acactgattt gccaaaatgc tgagctgaaa tctcatagcg cttctcatct agcagcctct
     8461 ggttcatttg aggtgtttct aaaatggcat caataatcgc atctgacaat tctgactcag
     8521 cataataaag tgttccaaac atcttatcgg taatcaaatc atctaggtag ggattgccat
     8581 gagcgatgat gggcttgcca ctagcaaggc tctcaatata agttagcccc tgtgtctcac
     8641 tcgttgacgc tgaaataaag aaatcacagg ccttataata aagcccaacc tgatcatgag
     8701 caatcatacc agtaaagacc acatgatcct caacgcctaa gctgacagcc agctccttta
     8761 aggcttgaag ataaggacca tcaccaacaa tgacaagctt gatcctgcta ttttcactca
     8821 aaacagctgg cagctgatgg ataatagcct gaatattctt ctcataagac acccgcgaca
     8881 ggctcaatag catggtctca tcatcagaaa tggccaattc ctttctcaag gcagcgacat
     8941 cttctttttt aatatcctca cgaacatagt tctctagtgc aatgccagtc ggaatcacac
     9001 gcttaggaat ggttacctcg tacccttcca aaagatttag cacaatccga cttgggcaaa
     9061 taacaccatc aaggtccttt aaatacccac gaagcagggg cttgaccatg ctaggtcgaa
     9121 tgatcttacc attagcaata tagctcacat aatcctcata ctgggtatga taggtgtgaa
     9181 caaccggaat tcttaaggcc ttgcccacca ttttgcccaa caaacctaag ctaaactctg
     9241 tttgagtatg gataatgtct aaatgatatt ccttagcaat cttgtaggag gaaatgagcc
     9301 cacgataaac cacacgacga tccgtaaagg acacaaaagg aacacttggt aaccgaataa
     9361 tggtcggatc ctcaaagcgc ttaacatgct tgtctgttgt tgtgaaaata tagacctcat
     9421 gcccctcttt ttccagctcc tcctttaggg tgcgaatact ggtagccact ccggaaacct
     9481 gtggaaaata ggtatctgta aatagaccta cacgcatctt ataactccat tactttttga
     9541 taaatagcca ctaattgatg agcaatccta tcaaggctgc gcccctcggc gacacgatag
     9601 ccggcctctg ttttgttgct ttcccctgaa agaatgcgtc ttaaggctgc aacaaagcct
     9661 gaggtatcat ttgccaactc agcactgtct tgatcaatcc agccctcata gactggtata
     9721 tcgcgtaaaa caagatgctg ccggctggct aaggcttcga gaaccacaat gccttctgtt
     9781 tcctcacgac ttgggaagaa aaaggcgtca gccccagtca tagccccctc atacacatct
     9841 cccttgatat aaccagggaa gatcacatta tcggggtgct taccgttgac aatctggcgg
     9901 acacgagcag gaataaccca tttattggta tcaccaaacc agataaaccg aacatctggc
     9961 atcatctcag caaccttaac aaactcatca atcccttttc taagaaagaa aagccccgct
    10021 cccatgacta ccttctcacc ctctttgagg ttaaaataac gccgaaaggc agcttctttg
    10081 tcagcattag caccatattg ctccaaatca atcccattag atactgcaaa aataggagtc
    10141 ttaaccccgt aatgctcaat caaggcttta gaataagggg tcggtgtgat aatggcgtcc
    10201 gccttattgt aaaagcggca gagataggct ttgaataaag gagacactag atttgaaaaa
    10261 ataaaggaat ttctaaaatc ctcctctgtc gaatgcccat gcatgatcac ctttttaccg
    10321 gccttttgag cctttgacat caaaagccag cttttaagcc cataggtatt gagatgaacc
    10381 aaatcatagt cgtcctttgg atcagtggtg aactcctgtc ccacaagcga tagcgctttt
    10441 gcctgatgct taatcgctcg cccgatacct gattttctta aataattttc tgcttctaaa
    10501 tacaataaga ctttcatact gtctattata gcctatttta tggtattttt cactaagaga
    10561 gttaaaaatc agcccttaga ctgattttag ggtaaggctt cttctacccc tatactcatc
    10621 tcaaaaatgc ttttaagtcc tgcttttgct gtcatcaaat ggctgatctt ggtaatatca
    10681 gctagaccaa gatcgtgaaa gctccagctc aaggctcacg tattagccct ttcaagaaag
    10741 cctcccacct ttctcactgg ccaaaaagcc agcaagacct ggccttttct tctgattaat
    10801 tcagcctatc agctaagctt cttcttttgg ctgtgctttt tgtaacaccc aggctgagat
    10861 agagcctgcc tctaccttga aatctgccca gccatcctca gcaacaacaa cagtctcctg
    10921 acaattgtct aagaaatcac aaaaaacttg accagcatag gcttgaccaa cctccatgtg
    10981 cttccagcct gcatcgccat tagacaaaac aactgccaaa ggctgaggac gctgatcatc
    11041 tcctaagcag gtccagccga tacaattggc atgatcaaag taatcaatct gctccccata
    11101 gaccagctgc tgcctgagct ctgccatttt tgtgataacc tccttaaaac tttgctgagg
    11161 gtagtctcca gaaataccat aataatcacc ataaaaaaga cagggcttgc cctcttgtcg
    11221 taaaagaatc aggccatagg ctaagggctt gaaccattcc tcaacagttg actctaaggc
    11281 ttgccctctt tgggtgtcat ggttttccac aaaggtaata gcaaggtctg gccgactagc
    11341 cacaagactg ccatcaaaaa tagtggtcaa atcaaaatca gctccctgct ggctagcatt
    11401 aaaaaaggac atgtgcagcg caacatcaac tagagcaaac tgagccttcg ttgcttcgag
    11461 gtaatcctcc atagattcct gatcagactt ccagtattct ccaaaaacct ctaaatcggg
    11521 ctttagctgg gtacgaatat cattgataaa ggtctgaata aaataagaat caatatgctt
    11581 cacagcgtct aaacgaaagc cctcaatacc agttgtctca ataaaccact tggcccaatc
    11641 ctgtaaattt tggattacct caggatgctt gaaatctaag tcattgtaca ttagataatc
    11701 aaaattacca tgctcatcgt caatcagctc atcattggcc cagcccttgt tatcaccggt
    11761 gatcatgtaa atacctgttt cattagcctt ggcgtcataa tccaatcccg taaaatggta
    11821 ccagtgccat ttaaagtcat tataggtatt ttgtctgccg ggaaaatcaa agcctgtcca
    11881 gccttcaatc tcatagggct ctgtaagggc ctgctgacgg ttctctggat tcattttgat
    11941 cacagaaaag cgttccttgt gatcaccatt agccttgtgg ttcagcacaa catcagcaat
    12001 aggctttatt tttgcctctt ttagggctgc aatcagctgc aaataatcct ctttgctgcc
    12061 atattttgtg ctgacagttc cattttggtt aaactctccc aaatcaaaca aatcgtaaac
    12121 accgtacccc acatcatcag agctagtgcc cttaaaggca ggcggcagcc acagctgact
    12181 aacccctagc tgttgtagct caggaatact gcttttcagc ctttgccaat gccttccatc
    12241 ggcaggcaaa taccattcaa aggcctgcat taatagttga tgactcatct taacctccta
    12301 aaaaggacaa accagaaaac tcctagtttg tcctcaaaac tgcctaaaca ggcagaacta
    12361 ttttgttgtc ccacgctttt taatgccatg gttcaataaa atttcttttt cttctaattc
    12421 ttccttattc atgatcttag tgagcatacg catgctaaca gcccccaagt catagaccgg
    12481 ctggctgata gagctcaaat ttggacgtgt gtactgaacg actggagaat cattgcttgt
    12541 gataatctca aagtcttctg gaacacgctt accagcttca aaaagaccat tcaaaaggcc
    12601 tgctgccagc tcgtcctctg caacataggc agctgtcgct ccggaattga tcacacgctg
    12661 agccagctca aagccttcct tataagaata gttggcctca aacaccagac cctctttaaa
    12721 gtcaagcttg ttcttcttga gtccgtcctt gtagccagct aaacgcacct ttccgttgat
    12781 atcatcaatg agcggccctg aaacaaaggc aatgctttgg tggtctttag ctaaaatatc
    12841 caccacatca gcaacagccg ccttataatc aatgttaaca cttggcagct gatgatccag
    12901 atcaaccgtt cctgccagaa cgattggcgt acgcgaacga gaaaactctg cccgaatctt
    12961 gtcagtcaag tgatgtccca tgaaaataat gccatcgacc tgctttgcaa agagggtatt
    13021 cacaacattg acctctttat catcgtcctc atcacttgaa gcaagaacaa tattgtactt
    13081 gtacatagca gcaatatcat caattccctt tgccagaata gaaaaatagc tatttgcaat
    13141 attaggaatc acaacaccga ctgttgttgt ctttttactt gcaagaccac gagcaacagc
    13201 atttggacga taatcgagac gatcaataac ctctaagacc tttttgcggg tattttcctt
    13261 tacatttttg ttaccattta caactcgact aactgtcgcc attgaaactc ccgcttcgcg
    13321 agcaacatca taaatcgtga ttgtatcatc tgtattcatt cttcatcttc ctttctaact
    13381 gaaaatgacg ctttcaaaaa gtattttagc atgatttgta accactttca agtattaacg
    13441 gttgattttt gaaaaagttt tcaaaaattc ataataagct tgctttttta agtatttttt
    13501 ggaaaaatag aaggcagaaa gaaggtttat ctatgactaa attagatcaa attcgtttgt
    13561 accttaatca ggaaaaggct gagcttgcta tcttttctga ttctgtaacg atcaattact
    13621 taactggttt tttatgtgat cctcatgaaa ggcagatgtt cctatttgtc tatcatgaca
    13681 aggctcctgt tttgtttgta ccagctttag aggttgcaag ggctgaacaa ttgctggact
    13741 tccctgtttt tggctacgtt gactctgaaa atccttggga aaaaatcaag tctgtcctac
    13801 caagcacagc agcaaagacc atttacgctg agtttgatca tttgaacatt accaagtttc
    13861 aagggctgca gagtgtcttt tcaggacgct ttgacaatct aaccccttac attcaaagaa
    13921 tgcggctcat caagtctgct gacgaaattc aaaaaatgct gattgctgga gaatttgccg
    13981 ataaggctgt caatgtgggc tttgataata tttcacttga cgtcaccgag acagatatca
    14041 tcgctcaaat cgaatttgaa atgaaaaaac aaggcatcag caagatgagc tttgaaacga
    14101 tggttttaac tggtaacaac gctgcaaacc cacatggcat tccaggaacc aataaaatcg
    14161 aaaacaatgc cctgctgctc tttgaccttg gtgttgaaac attaggctat actagcgaca
    14221 tgacgcgtac agttgccgtt ggaaagccag accaatttaa gcttgatatt tatcagcttt
    14281 gcttagaggc tcagctaact gctcttgata tgattaagcc aggagtgact gcagctcagg
    14341 tagatgccgc tgctcgccaa gtgattgaaa aggctggcta tggcgactac ttcaatcaca
    14401 ggctcggcca tggtatcggt atggacgttc acgaatttcc atcaatcatg gctggcaatg
    14461 acctgattct tgaagaaggc atgtgcttct cagttgagcc tggtatctat atcccaggca
    14521 aggttggggt tcgtattgag gactgtggtc acgtaactaa agacggcttt gagctcttca
    14581 cccaaacacc aaaagaatta ctatactttg aagggtaata ggaggcttaa aaagcctgaa
    14641 acaaaatgtc tcagacccta atatctaaag caacagcact tggtctgtta cttttcatat
    14701 tacaggctat tttctcacaa ggaaaagtca aagcacccct tgatgggaaa tcagaggggc
    14761 aaaagctatt tgtactaagc tcaaaagcta atcaagagca cctgaccagc tctttatcct
    14821 ttaagtgata aatgcaatca taagactgtg cattatattt atgagctatc tcaaccatgg
    14881 tgcaggggag tgaatggagt aactcacgaa tctctctggc gctttctttg tctagggcag
    14941 ctgtgacctc atcagccagc aaaatcggtt ttagtatcag caagcagcgt gcaatttcca
    15001 gcttcatgat ttgcccgcca gagagatttt gcccatctag atggagatca agatctccgt
    15061 ttagctcatt ccaaagatga acctgctgta atatctcctt tagtcgctgg tccgaataat
    15121 cctgaaacag cgtgagatta tctcgcaagc ttccttcaaa tatgtaaggc ttttgatgta
    15181 tcaaagacac aacatcatag gaaggaaaat agcgttttcc attggcagct tcaaaataaa
    15241 tagttccaga ataatcctta tcctcaccac acaaaagagc aaataaagta gatttcccac
    15301 taccactggc tcctgttagc aaggttttgt gccctgctga aatatgacca tctatccctt
    15361 gaaaaataag cctatgatca aaatacttat ctaacctctt aaagtagata tcaagtgtaa
    15421 gatcatctgt aggggttaag gcttgatgtt ttgtctcttc ctccagagcc aatactctaa
    15481 ccatcttctc cttaacagca gttgcagact gtaaactcga agtagcttct aataattgct
    15541 gcaagggaga gacaagattc gtagaagctg ttatcatagc aatgagagtt gttagtgata
    15601 gacttgaata gctcatcacc aacagaccaa taataagagg actaaccaag ccaatccctt
    15661 ttaatggacc agtccaaaac attaccagat tgtgggtagt ataatagcta tattgcttgt
    15721 cttccatatg ctgaatcatt tctaacacat ggtgagcaaa agcttcgttg gcttgattac
    15781 tctgtatcgt gtctgccccc ttagtaaaat cggtgatact ggctaggctt ttctccctcg
    15841 cctgactaag ctctaagcct cgtgattgaa gtaagtgatt gaacacaaac tgtggaataa
    15901 tcatcaaaaa gccaccaata gtaaaggcaa taccaatata aatatcctgc aaaagaaggt
    15961 acaagacaga ggctaagata gataggccaa aaacaggata aatgaataag gggaccaaat
    16021 actcctgcca aaacatagga atatcttggg tcaaaaacga atttaaggct gaagtaaaat
    16081 agttgagctg tttatgataa aaatgatata aagccttctt tgcaataagg caattaaacg
    16141 ctctaaccat agaacgtgct aaaatgttat taagatacat gcacatataa ataaagacaa
    16201 aaaaagctac gcctccaaga ccaaaaagca ataccattcc tttattgttc atatcaattt
    16261 gccctgctat ctgaattaat actgataaca atagtccctg caaggaatag agcaaagcca
    16321 ataaactata caagcaaagc tgccattttg aaatgacttg taaaatactt ttcatatcaa
    16381 tcactcctca cctgaaacct aaatgtatcg ctctcttgga aagtataaac gaaacatcct
    16441 catacaccaa tcatttccac cacaaactag attcttgaat gttaaatcaa gctcttgatc
    16501 aaaatcatgt tctctgattt cttgaacaac cattggttct ctcctttcat tcttactatt
    16561 tctagtatat aatgggaaaa aatacgaaag gaaaaatttc ggaaatccgg atatgaatat
    16621 cagagagaaa tttaaagcaa ttcgtaaaca aagaagacta tccttaaaaa cgcttggtaa
    16681 aatagctggc tcagccacta gtatttctga cttcgaaaat ggaaaaacga acctttctaa
    16741 tgatgtttta ttgcagcttt taggctttat gattgttgaa ataaacgagc tattcgaatg
    16801 ggaggatttt cacgaaaagg aattggttga agccatcaag caaatcgaac tggcaataaa
    16861 atctaaacat attcctgctc tatctcagct acagcaggac tttcaaagct tatctaagac
    16921 aaaggaacag tacatttacc acatcatctc actgatccta accatcacca ttgcagaata
    16981 tcaaaacaaa gagatcgatc cacacatcat gtctgagcta acagactact tctttttctt
    17041 ggagtattgg actaaccttg atgtcggcct actaggaaac atcgtccact acatgacaac
    17101 agatgcccta atcttattga caaatgacat cttagagcat acgcctcaag tactccgaaa
    17161 taacctagat cgtattagga tcgatactgt attaaactgt cttactgtct tgattaatcg
    17221 taaagaggag aaggcaagca gaacacttct taaattatta tttaacaaac attatcctaa
    17281 ttactttgcc tttgaaaagc tctatttaca tgaattacaa gcagtctatg attttaactg
    17341 gaaagataaa gaacaggcgc ttgcagctca tcacgtcata ctggctacca tttcattact
    17401 atttacagct gatgaagcca aagaatggga cagcttcttt caagaaagta ctagctcttt
    17461 gtaatactcc agctcataca ctaaagaaaa gcaaggataa tcacataaaa actaatcaca
    17521 tcactttgcc ctgctagctg aattagcttg ggtcatctct tatgcccagc aaaacatcat
    17581 ctagtctcag ctttcttcca aagcttcttg tctctctggg cttgcaagct tttgatagct
    17641 taagaggcac aagcattaac aaaggctaac aaatgcctgt aaaaatatgc tatgataggg
    17701 gtaacaaaaa cctaggaggt gcttatgtca cacaaatcca ttcatcaaca gcttagaaat
    17761 gctttttcct ttcggacagc ggtacgcgtc tacaatgacc aaaaaatagc caaagaagac
    17821 ttagacctga ttttagatgc tgcctggctc agtccttcct ctatcggcct tgaggcctgg
    17881 cggtttgtcg ttttagaaaa cgaagctgtc aagcatgagc taaaggaggt ctcttgggga
    17941 gcagtttatc agtttgagac agctagtcat atgatccttt taatcagcga aaaaaacgcc
    18001 agatatgatg gcgcttctat caagcaaagc ttattgcgca gaggcattac tgacgagcaa
    18061 gccttggcca gtcgtctggc atgctacgaa gccttccaaa agcatgatat gaaaatagca
    18121 gatgatcctc gggctctctt tgactggact gccaagcaaa cctatatcgc gcttgctaat
    18181 atgatgacca ctgctgcttt tatggggatt gactcttgtc cgattgaggg ctttaactat
    18241 gacaaggtaa atgctatctt agcaaaacat gggattatca accctgatac cgagggtatc
    18301 tctagcatgc tgtctttagg ctatcgcctg cgcgatccca aacactcaca aaccagaaag
    18361 cccagagaag aggttatttc cttctttaac taagcccctt ttgccattgc tcccaaagaa
    18421 agtgcaaaga cagtcctttg ccttttcttt ttcataactg tcgaattatg gtacaatgtg
    18481 tcaaaagacc tatggaaagt gatgcctatg acattattat ctgtaattat cccctgcttc
    18541 aacgaagaag acacgattat tccttatctt gaagaaatga agcaaatcga agcggccatg
    18601 accagccaat tagcctttga atatcttttt attgatgatg gctctacaga tcaaaccctg
    18661 agcgtgctaa gagagcttgc ggggcgcttc tctaatgtgc attacctctc cttttcacga
    18721 cattttggca aggaagctgg actattagcc ggcctagaag aggcaaaagg aagctatatt
    18781 acggtgatgg acgttgacct ccaggaccca cccgagcttc tcccgctgat gtatagcaaa
    18841 ttacaggagg gctttgatgt ggttgccaca agaagacaga gccgacaagg agagcctgct
    18901 atccgttcct tttttgctag actcttctac agattagtca agcatgtctc caacaccgaa
    18961 atcgtcgatg gggtacgtga ttatcgttta atgacaagac aggtggtgga tagtatttta
    19021 gagttgggag aggtcaatcg cttttccaag gggatttttt cttgggttgg ctacaatact
    19081 gcctatatca gctttgacaa tcgtaagcgg cagtacggca aaaccagctg gaactttctt
    19141 gagcttttga actactcgat agacggcttt atcaattttt ctgagatgcc cttaaccatt
    19201 gctacctgga ctgggacact tagctttttg ctatctctgc tagccatttg ctttattgtt
    19261 atacgcaagc tgctttttgg tgatccggtt tcaggctggg caagcactgt atccattatg
    19321 ctatttatcg gtggaattca gctgttttgc atgggaatca ttggaaaata catttccaag
    19381 atcttccttg aaaccaagaa aagacccgtc tacatcatca aagaaaagaa ataacagagc
    19441 aatcatcaag gcccctatca gccgccaatg aggccgataa ggactggttg ccctcatcat
    19501 gacaagcacg acaaaaagac ttgatggtcc caatcaaaac catcaagtct tttttagtat
    19561 gtgaccttgc gtctgcctcg cacctaaaaa gacgagataa tgtcataacc accgtctatc
    19621 tactgacccc aaaaagttgg acaatttagt tttaagcaag ggatttagtt ctgtattgca
    19681 caggactaag caaggccatc agcttgtaaa cagacgctta gcggcggttc acactcttca
    19741 tcacacgccg aatgtcacga tcctgctcgc gtcgcttgat cgattcacgc ttgtcataat
    19801 catgctttcc tttggcaagg ccgattaaca ccttggcaaa gccatcctta agataaacct
    19861 ttagaggaat aagggtcatt cctgtgccct ttagctcatc tgctaggtgc tgaatctcac
    19921 gctttttgag caataatttg cgcgtgcgct ccggatcagc attccagata tttccctgct
    19981 caaagggagc aatatgaaca ttgaccaacc aggcctcacc attcttgatt tgggcaaagc
    20041 cgtccttgag ctggatacgc gcggcacgaa cactcttaat ctccgtaccg gtcaacacaa
    20101 ttccagcctc aactgtctca acgatatgat agtcatgacg agcctttttg tgttgcgcta
    20161 atacattacc ttcacctttt gccatgctta actcctttta cgacctttct ttttagcagc
    20221 tttttggtaa aatggtttct ttgctttttt tcttgtcttc tgctttgatt ttggctttga
    20281 gggcttggac tccttactcc tgctagccct tgaagcagcc ttttgcctgt gcttatgctt
    20341 agctttagct gaccttgtgg tcttttcaac cacatcatag tcactagcca agtaatcaaa
    20401 atcaatgtca cctgtttcct tgtcagccct caccaatcta acccgaatcg gctgacctgc
    20461 tctaaatacc tttcctgagc gttcaccctt taaggagagt gtccgttcat tatagtgata
    20521 atattcaggc aaattggtaa tatgcaccag accttcaatt gtatttggca attcgacaaa
    20581 catgccaaac ttaaccacac tagcaatcac gccatcaaac acatcaccaa tataatctgc
    20641 catgtattct gcttttttca tcgcctcaac cacacgctcc gcgtcaattg cacgacgctc
    20701 tagctgagat gacgatactg ccaattctgg aataacctgt gcaaaatgat ccaccttctc
    20761 ctgcgtgatc tgattgtatt ctcgaatcat gcggtgcacc agtaaatcag ggtaacgacg
    20821 aatcgggctg gtaaaatgcg tgtagtagtc tgctgctaag ccatagtgac catgattatg
    20881 ctcagaatac ctagcctgct gcatagagcg cagcagcatc atattcaaaa cctctgctcc
    20941 aggacttcct tctacctttg ccataaaggc ctgcaaggct tcttgagaaa tcttattagc
    21001 agttccctga atctgaatcc caaaggcact agcgtaatca ataaaggtct gcaatttctc
    21061 tgcctttggc tcctcatgaa cccggtaaat aaatggcaag ccagcccttg aaaaatgctc
    21121 agcaacacat tcatttgccg ctagcataaa ggactcaatc atgcgctctg caacacctcg
    21181 ctggcgcaag accacatcaa ccggcatgcc cttatcattg acaataatcc tagcctcctg
    21241 cgtgtcaaag ttcaaggccc cgcgcttcac acgcatcgcc tctaagatct gatgcagctc
    21301 aaccatagta ctcacatcat cagcaattct atcaaattcc ctaagcgcct cactgtcacc
    21361 tgcaatcatc tgattgaccg cgctgtaggt cattctaaag gttgtgttaa tcactgactg
    21421 acacagctga taatcaacca catgtccctg atgatcaatc tccatgatcg ctgactgggt
    21481 caaccggtca acctttggat tgagagagca gataccattt gacaaccgct ccggcagcat
    21541 tggcaccaca cgatctgtca cgtaaacaga ggtcccgcgc gcagctgcct cacgatccaa
    21601 ggctgaccct tccgtcacat agtaggacac atctgcgata tgaaccccaa gctcaacgtt
    21661 tccattggcc aatctcttga tatggatggc gtcatctagg tctttagcat cagcaccatc
    21721 aatagtgatg gtcgtttctt tgcgcaaatc aacacgcccc ataagatcct gatcactcgg
    21781 agcatctgga atggcattgg cctcagctag aacgtcatct ggaaacgccg atacaatatc
    21841 catagattcc aaaacctcca gcacatcaat gccgacatca tgctgatgcc caataatatc
    21901 acacacagtc cctacaaaat aatcctgccc agccttaggg tattgcacaa tatcagcctt
    21961 aatgatttca gtaccatcta aggcaattgg agattttgcg atataaatcc tctgttgaat
    22021 cctttgattt ttcgacttga tgtagccagc atacttaggg tgatcatcat ctaaaataac
    22081 cctaccaaca accgtcttta aagagcgctc cacgatagct accacgcgag cctctgctgc
    22141 tgtagcctta agccgattag ctggtttttt aataacagcc tcaaccctat cgccatcact
    22201 agcatacccc acatcatcac gaccaataaa aatgtcgtcc tcattgtcat caaccgacaa
    22261 aaagccaaag ccagccttat tggcacgaaa aataccttga acccttatct ctggcttttt
    22321 ttgctgtggt gctctaagaa acacctcacc ctcatctgaa aaagacaaaa gtcccttgcc
    22381 ttccattttg gaaatggctt taatcaggcg aggaaagctc ctcgcatcag tcatctctag
    22441 tgcagccgcc aaatcatgaa tatttgattg gccatgctcc tttaaataat tcgtaatgtt
    22501 ctctatcatc atacctatct tctatttcta acaccatact tgatggttgt gctcattgat
    22561 aaaaaaatga gctagactaa ctctgtcaag ctcactcctt atttacttga taaaatggca
    22621 agcactaacg caattcctaa ccaaaaaaac actagaactg ctgtaaaacg ttgcataaaa
    22681 gcttcaaatc cgcgagcttt tgtacgctca aacaaggctt ctgagccact gctatcaaaa
    22741 acattgctac taggattttt ttgtggctgc ataaagatag caatcacaag caacactgat
    22801 aatactagca atatcgtaag tagtaagtcg tacatgttaa ttcctccact gtagtctcaa
    22861 tcattctaac acaaaaccaa ctaagattca acatgcagcg ttacttttct ctccttagga
    22921 cagtatttag gaaccttaat cttctcaggg tgacttgttt tatttttact agtcaaataa
    22981 tttttgctgc cgcaatggct gcactccaaa tgaatcttta ctctcacatc atttccctaa
    23041 tcttactata ttttatcagc gtcataaggc ttcaaatcac ccgcagcttc tttattaaag
    23101 atatctctag ttattatagc atattatcca gtaagaaaac aaactcagga cttttagcaa
    23161 aaaaggctta agcgccaacc aataaacatt ccaaggctat cggggaatat tttctaatgg
    23221 ttattataaa tcatgaacaa ttacctaaca aagcaactcc aaaacaaaga taaaagacga
    23281 acattcacct tgctgctcag ctatcaagat aaacaatcct gatagcatca attttcttta
    23341 ggtcctcagc aatcggttgt aatatcagac aattcaggtg ttgattaaaa aaaacgaaac
    23401 tacggagacc aattgtcaga aagctattca cagcccgcag gcgtcgtgct aaagtattgt
    23461 ctggaaaaag aaaggtttag gaatgattat acctaaactc aaaggagaga aacaatgaga
    23521 aaaacaatga agaagatgct agcagcctcg acgctctgca tcatcatgtc aggcagcttc
    23581 atcagcggct cagctagagt gttggcggag aagtattatg gttttaatga tggcacagga
    23641 gagcattcac cattccctgt atacgttact ccaattacta aacctaatag gaatactgcc
    23701 aaagttgtct actgtttcaa taaagatatg aagtggccag aaacttggga taaagcagca
    23761 ccaaaaaaac cagataattt acctctatac tacgatatgg aaggtactga tcaattattc
    23821 agtacatatg caagtggaca acttactcct aatgtcagta aagtcttagc taatataatg
    23881 gctaaaggtt atccaaacaa caatgagttt gctcaccatt ttaaactcac tcccaattcc
    23941 gctgtaaaag ttactcaaat cgcagtttgg actgttacgg ataacctaaa aaactattct
    24001 caatacagtc taaccagaga agaggaagct gcattaaatt acctaactga caaaaatggg
    24061 gacgacttta gcgatagtat caagttaaaa ttatacattc cacaaaatcc tcgaactata
    24121 aaatatcaaa atcttctagg ttatgaccta atagttaaaa ctccagaaaa aaaagataat
    24181 tgtaaatgca ccaaaattta tatagaagat aatggaaaag atggctatta tctgtatatt
    24241 tattatgaca acaatgaaaa taatagatat gactcggaca aagatagcct attgcaaaag
    24301 aaatacataa aaaatgggaa agatgggaaa ccaggaagac caggggttcc aggacttcct
    24361 ggccctgctg gacctcaagg gcctagagga gacaaaggag aaaccgggga acgtggacct
    24421 aaaggtgaaa aaggtctaga cggtaagcct ggtgaaaagg gtcctaaagg cgatacagga
    24481 aaagatggta aggacggaca acccggacct cagggaccta agggtgaccc tggacgtgat
    24541 ggaaaagatg gcgaacctgg aaaacctggc gagcgcggtg agaaaggacc tcaaggcgaa
    24601 cgtggacctc aaggacttcc tgggcccaaa ggtgagcctg gaattccagg gcctaaggat
    24661 gaagatggaa aagatggtgc tcctggacat gacggacaac cggggcctaa aggtgaaaaa
    24721 ggggaccctg ggcaacaagg cattccagga cctaaagggg aacctggacg tgatggtaaa
    24781 gatggagaaa aaggcgagcg tggagagcaa ggacctcaag gcgaacgtgg agagcaagga
    24841 cctcaaggcg aacgcggaga gcaaggacct caaggcgaac gtggagagca aggacctcaa
    24901 ggcgaacgtg gagagcaagg acctcaaggc gaacgcgggg agcaaggacc tcaaggcgaa
    24961 cgtggggagc aaggacctca aggcgaacgc ggagagcaag gacctcaagg cgaacgcgga
    25021 gagcaaggac ctcaaggcga acgtggagag caaggacctc aaggcgaacg tggggagcaa
    25081 ggacctcgtg gagaaaatcc tactcctacc ccagatccaa tgccacaacc agaaccacaa
    25141 ccagaaccac aaccaatgcc tgatccagca cctaaaccag aatccaagcc agaacctaag
    25201 ccgatacctc aaccagaggt taagcctcag ccagagacaa aacctcaaca accaaacaag
    25261 ccatcaacca ttactagcca atctagcggc aaatcactgc caaaaacaaa tgacactggc
    25321 agcttgatca cagcatttgg tacaggctta ctcactcttc ttggactagg cttcctagca
    25381 aaacgcaaaa gaaagcaata attaaaacac tacccatagc cttttaatca ttggctatca
    25441 actagataac aaaaagctta tcgttttact cctaacgata ggctttttcg cattccctat
    25501 tgcttggtct caatactatt tttccagctt taggctggtt ttgctaatcc aaaataatat
    25561 cagacaattt ccgttttaat taaaaaaaaa aaaaaacgaa actacggacg ccaattgtca
    25621 gaaaatggtt cacagcttag agtcaccatg ttaagctatt ctacgaagaa gaaaggttta
    25681 ggaatgacta tttctaaact caaaggagag aaacatgaga aaaacaatga agaagatgct
    25741 ggcagcctcg acagtctgca tcatcatgtc aggtagcttt atcggcggat cagccagaat
    25801 cctagccgag cagtattatg ggtggaatga tggaacaaga gtaaaatcac cttttttcct
    25861 ttatgttacg ccaacaaatg aaacgactag gaaaaccgga aaaaatggta caatagtcta
    25921 ttgtttcaac agagataagg aatggccagc aaattgggaa gaaggaagat ccttagaact
    25981 agtgaatgct gaaacagctt ataaattacc catctataat aaattactag gtacaactga
    26041 ttcctttact aaaaatgcta gtaaaccaag agtatctgga gatattggta aagcgctaat
    26101 agctgtactg aaaaatggtt atcctaataa aaatttatcc ggattagatg acactaaaag
    26161 tcgaatacta actcaactag ctatctggta tttcagtgat agttataata aagattattt
    26221 taaacaaaat tatgaattaa ctgatcaaga aaataactct cttatggagc tgattaaagt
    26281 cggtgaggaa gcagctcaaa aacaagaaaa accagaatat catttagata tatatataac
    26341 tacagaaaaa aattattaac ataaacctta tcaaaacctg cttggttcta ctctaattcc
    26401 taaacttgac cctaagcctg aaccagaacc agatcctaag cctaagccag atcctgaacc
    26461 aatgcctaaa ccagagccta agcctgaacc agagcctaaa cctgaaccta agcctgaacc
    26521 aatgcctgat ccggcaccta aaccagagcc taagcctgaa ccaatgccta aaccagagcc
    26581 taagccagag acaaaacctc aaaaaccaac caagccgtca aacgctacta gccaatctag
    26641 tggcaaagca ctaccaaaaa caaatgacac tggcagcttg atgactgcac ttggtacagg
    26701 cttactctct cttcttggac taggcttcct ggcaaaacgc aaaagaaagc aataagctga
    26761 ataagctaat gcaagacagc actagtatat aatgcgtgca tggtccatct aatgcagcac
    26821 aaaagcctta tcgcaccacg aatgggtacg ataaggcttt ttgcatacgc tatagaagct
    26881 ccaaaaccac tagactaggg caacagcatg gcaaggctta cgcctctaaa tcatgcagag
    26941 ccttactaat ctgtgtctct aaagcctgaa aatcaccagt attatcaatc actaaatcag
    27001 cataagctct tttctgagac atcggcagct ggctagcaat ccgctgccta gcagctagct
    27061 ctgtcaattg attacgcttc atcaggcgct tgagctgagt ctcctcatca acatagagca
    27121 gccaaatagc gtcaaaccaa tcctgatagc ccagctcaac taaaagcggt aaatccataa
    27181 agaaaatagc ctctgtttga gatagctcct ctttttgctt ggctaaggct tccctaatga
    27241 tagcattctg ctgctgggaa gatttcgcca tattttccga atgagcaaac agcagctccg
    27301 ctagcttagg tctgtctaat tgccccgatg gcaataaaat atcctgtcca aaggtctcta
    27361 gtaggacctg ataaagcttg ccgccctttt tttgcagctc atgcaccacc tgatccgcat
    27421 caatcacctg gtagcctgct tgtctgataa gtgcgacagc cgttgatttt ccggaggcaa
    27481 tacctcctgt aatgccaatt acctttgtca ttgcttctga cacctaggac agacatgtgt
    27541 ccctcttcct ccaaccttga gctttacaat ggaggtcccg cagcgctgac agggcttgcc
    27601 tgtttggcca tagaccatca aataatgctg catactacca ttcattccta aggtattctg
    27661 ataggttcta accgtcgagc cacccttttc aatacctaat tgtaaaatac gaatcgtttc
    27721 atcatgaatc cgtttgattt ctgccttttt caggctagca gatcgacgct cagggtgtac
    27781 tctagctgcc catagcacct cgtccacata gatatttcca agaccagcca ctaaagtctg
    27841 atccaaaaga tgaggcttaa tggtcttttt agaggctagc agagcagcct caaaggtctt
    27901 caattgaaag gtctgcttcg tcggctcagg accaagctga cgcttctgga aaaaagcagc
    27961 cagctcagcc tttggtagca aatcaaaggt tccaaacttt ctcacatctt ggtaaaccag
    28021 cgtggagcca tcagtcattg tcaaaaagac atgaaaatgc ttatgctcag gtaccgtatc
    28081 aggaaacaag aggtatttcc cctccatacg caaatgcgag atcataacca gctggccaaa
    28141 gtcaaagagc aggtacttcc cgcgacgatc taccccttgc acctgctgcc cagggatcgt
    28201 catcacaaaa tgctcaaggt ctgttttgac catcttgggc accctaaccg tcactgctgc
    28261 aatctgcttg ccaacgacta agcgctcaag cccgcgtcgc actgtctcaa cctcagggag
    28321 ttcaggcata attaaagata ccaaacgcgc taacaaagaa accacataac caaaaccagc
    28381 agaaccagcc agttttagca ctctttactc agtctcaatg ttacaaacac gcttcctttc
    28441 tataagctac tattagaaag ccccacccaa aacctcaata agcttgagca caaaggacta
    28501 tcctttgata agaactgtta tcattcttat tttacgcata atccataaag aaagcaactc
    28561 tcacgaacag cctttgcagt cactgccgct atagcatcag aaaagcacat ctcgcccgcc
    28621 aatccagcaa gcaaagacaa agcccctgag ctagcctatt gtttgccagc ccaagggcac
    28681 gttgtggcct ttagtgtctg taaatagaaa accaagcaat gctgcaagcc tcaactgaca
    28741 atgctaggtc tgatcagtcc tgtcatcagc ttgcggataa tctatactaa ttggcctatc
    28801 aacaagacgg atactatcct ggtaaacacc ttctgtttca aaaataacaa tgtcatttaa
    28861 tcccttgttg aaatagccct ttggaatata aagggttaat aagggaccca cttcccaaaa
    28921 acgaccaata gggtgattgt tgataaagac acaacccttc ccaaagccag tcatatcaat
    28981 atagcttgcc tcaggctcat gacattcaaa ttgataatga taaaagccgg gctgcccctc
    29041 gtaaaaatcg ccatcaaaac aaagctgaga caaatcatca agcggcagac aatacatctc
    29101 ccaattggtc acaaagtgca agtcagccat cataccacgt cctagaccct tactttgact
    29161 aggtgctgtc agcttgtgcc cataattgac ccggcccata ttttcaatta aaacatcgac
    29221 ctgactcaag gcatgctgct ggttaatgat gatatcatca ccaatcgtct cctgatactg
    29281 tgttgcaacc ttttgaccat ctaaaaagac ctgtgctcta tctctactat caatcaagcg
    29341 taaacgctcg tcctcacgct tatccttcaa aagatgtgtc cgatacagga tatagcccgt
    29401 tgattgccct aaagcctcta tgttactagg atagcaagca gtctgacagc tgctgatgtg
    29461 ctccagcgtg ctaaacagac taaccttgtc cttcagacca atcagaggca gtgacatcaa
    29521 gggcttaatc aagggaggag taacctctat ctctgaaagc tccgcggtca gacgcttttg
    29581 aatcgcgtaa aacttagctg tcggattgcc agcctcatct aggatagcgt cataatcata
    29641 ggaggtcacc tgcggaaggt ccaattgctt tctggcagag cagccattca taaacccaaa
    29701 gtttgttccc ccatgaaaca tatacaggtt aatactgccc tgcgccaaaa cctccatcac
    29761 tgcgtcagct cgctcttcag ggtcgcgttt gatgatgggc tcatgccaac gattgaacca
    29821 gccgtcccaa aattccatac acattaaagg ccaatgcttg ccatgctcag aaaagaaggc
    29881 ctgcatgtca gcaaaattct cctgtgccct tgagccaaag ttgccagtca caaagacatc
    29941 atcttcaatc agactaccag ctctaagagt ggctcgccaa ggaccatctg ctgtaaacaa
    30001 gggcgcactg aggtgctcct ccataaagcc cttaacagct gttaaatagg ccttatcctc
    30061 tccataggag ccatattcat tttcaagctg aaacatcaaa atattgccgc cctgctgcca
    30121 ttcatgcctt gctagtctcg gcagcagctc ctcataatag cgcctcacat aggctaaata
    30181 gacaggatca gacgacctga tatgacaatt ctttgtcagc agccaagcag gtaggccacc
    30241 aaattcccat tctgcacaaa tataaggact aggtctgaca atagcataga gccccaattg
    30301 ctgcgccagc gtcaaaaagg cttccacatc taattggcca gagaaatcat agctttcctc
    30361 cctagcctca tgtaaattcc aagggacata ggtctcaacc gtattaaatc ccagtgcctt
    30421 taaattataa agcgaatgat accaatcatc tgggtgaatt ctaaaataat ggatagcccc
    30481 tgacaggatt tgcagcgatc taccatctaa ataaaactga tctgaaatct gaaaacgttc
    30541 caagcttaat tcctcactta ttattgctat tagcctacta ggcctcattg ctgagcggct
    30601 tggaatggcc cattctagca acagcgaaca ggccattcag cagacaggct aacttatctt
    30661 atggtaacaa ttgtaaacac tatctacagt ctgactcctc atgctatgct gtcacagcag
    30721 caggataaga gacagtgtat gccttgtcat ctgtcaatct aatcccatat ttggtttcaa
    30781 caatagtatg gtcaaactgc ggtaaaacag ttatcggtcc ttcaggcata ctctccagag
    30841 acaattcaaa tatcgctgtg tctgtgccat ctcctgaaac atagctggca agcttatcta
    30901 cgccatttac agtaactgct aactgacgat caccaagaat aaacatcggt tgattaaagg
    30961 tcatctgaat ggttatgctt actttgccat tttgctttgg agctgctgac gttattgtta
    31021 cttcttcaat ttcagcctta tcctcacgaa actggtctga gatcatctgc ttgatattaa
    31081 aggttgaata ggtgatctga ccactatatt cgtataacaa accaaccctc tcgtcgtcta
    31141 gttgaaccaa gctagagtaa gcaaaacgct ttggctcaaa aatggttgaa gcgacccaat
    31201 gaatgctatc gtcctctaag acctcaccga cacgcagaat ccctttcatg cgctgatttc
    31261 taatcgtcag ttgctcacct gagggctctc ctaaaggatt ggataaaaca acatattctt
    31321 tgccatcaac catcatatga atagctgaca aattgacata aggctctggg aggtctgtga
    31381 ttgtaggatt atcgtcccaa gtcataccat agtctgtgct tctggcaata acgattgtct
    31441 ttccggtatt gcgcataaac tgtaataagt gaccattgtt tagctgaatg atttgatttt
    31501 ctgtcaattc tgtgactgat gtatcaaaat ccttagaggt tgtttgttgg ttatgaccat
    31561 aaattctgcc atcatttggt gattcacctc gttgccatgt ttgaccgcca tcatcactaa
    31621 aaatattagc actgctttga cgacctagac tagctgatgt cgcattttgt tgattggtat
    31681 agtaaatcgg gaaaactaac cgtttcacct gctcaccctc tgcattgact gcgtctattt
    31741 caatgccagc tgcggcaccc gtacctaaaa atcccatcca gtcttctttt atttgtgggg
    31801 taatatcaag aggtgtggac caggtttgcc cttcgtcttc actggttagc agccataaaa
    31861 agctggtcat gtaagtaaat agaggagctg tttgtgagcc ttctctagtg atgccttgct
    31921 tagtgcgacc acttctcaga taaatattcc ctagtagaat atcctctcct gcctctgttt
    31981 gatagaggtt gccgcgtgtg ctaaaggctg tctcaaaatt gccctcatca acatacatat
    32041 ctgtctgatg gccactctgg tcatagacga taccaccttc acgcacagtg tatttattat
    32101 tgtcaaaatc ataaagattt aaataatact gaccgttaat caattcatat cctgagcctg
    32161 ctttagaagc aacagcaccc tgtgactcag gaaagacatc taccagcaaa taaagcttgc
    32221 cagaagcgtc tgttagcaag gtggagtcta ttgaaaaagc agattgagtc atgttggtat
    32281 tccaatcagc caagctatat tgtgttgtaa aataaggctg agttggcata tctaagaccg
    32341 taatgttatt actccaggtt ttgccatcat catggcttat cctgacaaca gttgcaacat
    32401 ctccccagtc attgtagtgc ttctttcttg catctgctgc ggctatcaag gttcctgatg
    32461 gcgttttgac aacagaggga atccgatatt caaagacccc ttcatcatat ttgtcccaaa
    32521 cattcgtctt ttcaccagta actggtcgaa gggttggctg atgagccttg gcaatatctg
    32581 tcagatcata cacatctgta tcaatcagca cctgatcaac cagtcccttt aacccccagt
    32641 gaaggaccga ctcaccatca taggtgcgtt tcaagcctcc aattgttagc gtatcagcag
    32701 aagccttcca aggtaattgc ttcataaacc cagcaaagtc agcttcccca tataagtcac
    32761 cattcaagta aatctttagc ctagaccctg taaagacata gctgatcgtc tgccagtccg
    32821 agttcgttaa taaattaaag cctgagccaa cttttacaat cggaacctca gctcctttaa
    32881 attcaagacc tattttattg tttttaggct cgataaagaa agaggcgtat tcattagctg
    32941 atgcttgatt tgagatcgat aacaaggcca agggcgatga gcttctcact gttgtatcag
    33001 cagtatctag acggtatctg attgttacag ttccttgggt taggttcatc acatcgtcta
    33061 gcttaccaag agcctcgtca tctgttacgg ctgctttttc tgctgttgcg tccaaaatag
    33121 cattgcctaa atcaactaaa atggatgctt gatctgagat tggctgatct gagatatagc
    33181 ttgcttctat gcttgtataa acagctcgtc cgccttctgt ggtgtatttg atctgataat
    33241 gctctgcact tcccaagatc tcctctggcg taacccattg ccaattggct ggcagggcta
    33301 ctgtagataa gggttctccc ttcttaccaa tcagaccttc tttaggtaat acagttaaaa
    33361 tagctacttc tcttgcaatc ttagcagttg gtgttactgt tgagcctaaa tcagcattgt
    33421 aaggaacagc actatagtaa atgttataaa taccaggagc tagctcagac aaggctgaca
    33481 aatcatctcg accagcagcc tgtaaagcag cattggtatt tccacccttg ttagtaaaca
    33541 agtattcatt ttcaactgaa aaatcaacca catagccttc ctgatcagtg gttacagctt
    33601 gagctaaatc aggactggtt ccctctagca tggtcaaatc cttgaccccc ttgagaactg
    33661 gctgtgaggc ataataagct tctgaggctg ctttttgctc agcatcttgg taataacgca
    33721 cataatcaat cacaaaggcc gtctcatctg aagctagata gtagcctgca tttttactcc
    33781 aattgcctcc agtagcaagg ttaaactgaa ggtattgagg cttattaaag gcagctgcgg
    33841 cagcctctaa gcgatcatca ccggttaaat acatggtatt ataaacaatc ccatcaacat
    33901 accattcaat cttatccgga taccaattaa taccaaagat atggtagtca tcataaaagt
    33961 catcacttaa tgtcagattg ccacccaatg ctgttgggct atagcttcca tctttgtctg
    34021 catcaccctt gatatagtaa aaatgagggg tcccgtaaac tgttttgttg ctttgatcac
    34081 cttcggcaag ctcaccctca tgctctccgt taggagcacc gattagctcc ataatgtcaa
    34141 gctcacctgt gcttggccag ccatagcctt gagttgacgc aatatcacca tctaaggtaa
    34201 aatcagcccc caatgtccaa aaggctggaa aggctccctt acccttggga agcttggccc
    34261 tagcttcgat acgaccatat aaaaattctt gcttgccaac cgttcgtacg cttcctgaat
    34321 cataaatgac ctgacgtgcg cttgttcctc ctctaggatt ggcataacgg tcctccccat
    34381 aacgctctgt gacgtttaaa acaagattgc cattatcaag atagacattc tctgtgctgt
    34441 ctgtgtagtg ctgctgctca ttcccgcgaa tacttcccaa ttcatatccc cagttctctt
    34501 ggtttaaccg atctcctgaa aactcatcct gccaaatcaa ttcataatca ttttcctcta
    34561 cgacactcac gttatcaata ctagcagagg cagccaaggc ttccggagaa gaggcttcca
    34621 accatttgac taagccaaca aaggtttctg aagtcgttgc tgtaaaggag agcttgatat
    34681 gtgaccaagt accgtctgta tctgtgaggc tgacctcttt gataacaggg ccctgaagat
    34741 tgtgattgga ctctttagcg gtaaggtata agccattatg aggtgtgtca gcttcaacct
    34801 tcacatcagc ctctagcgta taggttttcc caaccgttgt agacaccttt tgaaggatat
    34861 gctcatctaa agtgccgctt gttacctcag catagctatt accattctct gttgtgagga
    34921 ctgaatgacc tccctctcta tattgccact gattcttatt ggacacataa tcattgtcaa
    34981 aaccaccatt agccacctta ttgagctcaa tcggagcgtt agacttctct tcgtctgctg
    35041 tctgatcagc agcattgctg gtcacagcat tagctactac tgcctcatct actgtcgtct
    35101 cctctgagac tactaaggcc tcgctatctg tatctgtagc ttgaggctcc tgctcatggc
    35161 ttatctctgt tactgctgct ttcgtaggct gctgcaggct tacctctgaa acgtcatcag
    35221 cataaacagc cactggcaga ccagcagcaa gaccaatacc cacacacact gaagcaacac
    35281 cgacactaag ctttttgatg gcatattttc taatttgctc ttttccgata ggattaaata
    35341 acatgtttat ttcctcactt atatatacat catttttaaa cacaatagct tttcaaaggc
    35401 ccatttagcc taatccagtg ctggtcaggc taacgacctt gttataaaaa cgctttcaat
    35461 tcagcgctta aaagaagata taccagatga aaccgatata tcctctcaca aagtgactaa
    35521 cctgcctttt caagctcatt atcagccatc ttaacaaatg gaaggtaaat cagggttgcc
    35581 aaggccaaat tgacaagcga tagcacaata gcacgccaat caaaaccagt tgaaaagaag
    35641 ccatacaaga caggcggcat tacccaggtc acattttgcg taacgggtgc aaccaagccc
    35701 agactagttg cgatataagc aacacttgac ataacagcag gacaaacaat aaacggaata
    35761 aacaacaaag gatttaaaac agttggtaaa ccatacatca ctggctctcc tatattaaac
    35821 aatacaggag caacacctag cttagccacc tcacgatagt gttcattttt agacttccag
    35881 aaaatagcaa tcaagagccc taaggttgca taccatacaa agaacactcg tccaaagata
    35941 aggaatcgcc tcatgctttt gataagcctc caaattagcc aagagggcaa caccaaatac
    36001 tccctccata tttggcgcca taacattgcc gccatgaatc ccaaagaacc agaaaaattg
    36061 ggtcaaaaca gctaccaaaa caacagcaat aaagctttgt gataagccca aaagtgggat
    36121 ttgcaagacc ttatagatcc aatcaatcat caaagaaccc gttagctttt caaagacaaa
    36181 tgttaaaata gctacgctat acaaggcgca aaagcctggt atgatagata agaagggctt
    36241 ggctacagca ggtggcacac tatctggtaa tttaattgtc caatttttta acattaattt
    36301 acaaaaaata atagaggcta aaaagccaat cataattgct gtaaaataac cattggagtt
    36361 aatttgcgca ccaggcaata ggcctgagat ggtcacatta agtgagctgc cgctgacagt
    36421 aacaccactg tccttaaaag ccgtcacaag atcaacaccc ttgagacctg acgcgtcaat
    36481 gctagaggta acagaatccc caatcgcaat cacaaaggca gctaaagaaa ccaaacctga
    36541 tgagagcgta tctgtcttat aaagtttagc gacattaacc cctaagcaat acacaaatag
    36601 caaggacaca atcgaaatgc ttcccttaaa gacaaggttg ttgatggtta cccaccattg
    36661 gaaggcctct gtaatgcctt gcaagccaaa ttggtctgga atatccacta aaaaggcatt
    36721 gatcaacagg gcaatagagc ctgtcatcac aaccggcatc gttgcaataa aagaatctcg
    36781 caaggccact aaaaatcgtt gattaccaat cttcgtagca attggcagca gcttttgcga
    36841 aagaaagttc atatagttat tcattcatag ctccttaaaa caatcataaa acagctaaga
    36901 tagagcagta aaggctctct ctaacagctt agccttcatt tttagtttgc tcgctcgcct
    36961 gccatcttct ttccacatta ataataaacg gcaagtaaag aagaatatct agaataatta
    37021 aaacaagctg taggactgag gcttgccagc tgcccgttgc caaaaatcct gaaataacag
    37081 gcggcatggt ccaccccgga tcagcatagg tgccaggtac aatgccagaa gcaaaggcaa
    37141 aataagcgac aaacaaattc ataacaggtg ctagtacaaa aggaataact gtcaatagat
    37201 ttaaaacaac cggtaagcca aacatggtcg gctcgttaat gttgaaaaac cctggaatca
    37261 aggtcaatgg tgacaagacc tttgcctgct gactagcctt gcgacgacgt gctaaccagg
    37321 ctaaagccaa caccaagcca atggttgcac cagctccgcc gataaaaaca aagttatcca
    37381 taaagacaga cgtaaagaca tgcggcaatt cctgaccagc cttatgagct gccatatttt
    37441 cagtcaagtt agataaccag atcggcttca taataggatt gtttaggaca tttccaccat
    37501 gcacaccaca gaaccataaa aagccattaa gaagaacaac gataaaatta ccaaataagg
    37561 tacttcccag caagccaaat ggaactccta gtacggactt aacaatgtca tggacatttg
    37621 gcaggctaaa atgatccaag aaagcataaa cagcaagcca aaacacaata atcaccgctc
    37681 caggaataat ggcgctaaag ctttttgata ctgcaggcgg cacaccctca ggcatcttaa
    37741 tccgaatatc ctttttcata aaccattgat aagcatagcc atttaccaat cccaaaacaa
    37801 tggcaacaaa caagccgcct gatgaaaggt aagaaggcgc aatacccgct acctcaccca
    37861 aggctttacc agattcattg acaaatgaaa cagtaaatgg ggtcactgtt aaaaaggcag
    37921 agatattaat aatcccagca gaaatcccgt ctgccttata ctgcttagcc aagctataag
    37981 aaatcccaaa ggccgcaacc aaggcaatca gattaaagct cgaatctact cccttccaca
    38041 gataggtaga gacaccaatc tcaccaagcc aagcttccca accaggaatc ggcaggctag
    38101 caatcaccat taaaaaggac ccaatcaaaa tcaagggcat agcgtaggtg atcccatcac
    38161 gaatagcaat aagaaagcga ttgcttccta ggcgaccagc aactggaaca agcttttgct
    38221 ggataaaatc ttcaaattta gtcattgtta cctccttgtg acgttaacct ttcataaata
    38281 gatactagct cccttgccaa atcaacaaag gtaatactag tcatcaaatg atcctgacca
    38341 tgaactaata gtaggcttac tggtgtagca tttccccgtg cctcttgagt tagcatatct
    38401 gtttgtgcat gatgggcctg caccaatgcc ttatcggcct gctttagact ttcctgagct
    38461 tgattgagct ctcccttttt agcaaaagca atcgcctcca tcgcaagcga cttggcacta
    38521 ccaccatgca tgatcaggcc cataatcgtc tctagctgct tatcttccat gaccaccacc
    38581 tatttcatca aactttcagc taaggcaata accttatcac cattcatcat accgtaatca
    38641 accattggca caaccgccac tggaatgtcc ttttctgcca agctttcttg aaatgctgac
    38701 aattgataag caacctgtgg ccctaataac accacatcaa caggatggct tagagcgtaa
    38761 tcctctgcct cagtcaatgg caatgcaaaa atatctgcct caagcccccg attgtcagca
    38821 gccttttcca tctttgtcac taatagactg gtactcatac ccgctgcaca ggccaacata
    38881 atttgttttt tactcatgat cttctccttt atcccaaatc ctaacgtcga atagagcgcg
    38941 acattctcac aatggtatgt ctttttcctc ggatagcgtc actaagagca aagatatttt
    39001 ccactggcgc aatcccgcta tagccagcat ctccgatatg atgaatatcg acaccacaga
    39061 ttttattgcg aatagcaatg tctcgaacga tcgtagtatc tgacccttcc tgactcgttc
    39121 caatagctga cataactaga gcatcgtgag catgcacctc ctcaacaata gctctaaggt
    39181 caccctctgt aaagccagga actgtcccaa cagcaggaac taaaatcaca tcagccccag
    39241 cctcgataaa ccgccgaaca gtttctaagt caatcaccgc ttcattagag ccagcagcat
    39301 gcatctttcc agcaataatc aagcctgaaa aatagtgctt ggcctgttga atagctcttt
    39361 caatctgatt attgctaaca ccagtacctg gatttcctgt caagcaaaca aagtcaaagc
    39421 ccaaggcttc aatctcttga aaggtcttag ctgtcgcctg tcgcccttct actagctcca
    39481 agcgcttttc agtcatgtca acgtccaaat caattggttc taaattaaca ccaattggac
    39541 gccccaccag acgacgcagc tctaaaatag gctgatcagt agcaggtaga ccagatattt
    39601 gaacatcaaa gacatctaca caattcagca aaatcaaatc agcactaaag gctgcggcaa
    39661 cctcagcgtt cgtaaggtca tctccagtcc aagagggtct tggcgctaca ttttctgaga
    39721 caatggtacg tccctcgctt gccttaatgg cttgctttag ctctaacgat gttaactgta
    39781 gcatttctga gctactagca ctcaataatc gtgttttcat cgcttctcct ttatttttat
    39841 tttaaaaaca ttaacaaaag ataaataaga tttaactctt atttgtttac tttttataaa
    39901 caaataaagt atattctatt taccaatatt tgtcaacgtt ttcaggcagg atttttaatt
    39961 cttttttggt atgatagagg tacgataata gaggttacta tgaagacgga taaacaacaa
    40021 gagctttacg caaaaatttt agataccatt tatgcccaac ggcctatttc acgcattgat
    40081 atttcaaagc taacgcacat cacacctgct acagtagggg ctatcactaa agagctgcta
    40141 gcacaggggt ggatacacga aatcggagag ctgacggacc actccgttgg ccgcaaaaaa
    40201 atattacttg atgcttcggc taacgccttt tattttgctg gtgtcgaatt gtccgaaaag
    40261 catttctatt tggtcattac agataacctg ggcaccatct atgccaagca caaccaacag
    40321 atcgacccaa gcatttcctc ctactacaaa gcagactata tctctgagct gattcaagcc
    40381 ttcctcaagc agcacaagca ctatgatgta caagccatag gaatagcact gcctgggcat
    40441 tacgatcatt ccacctccag ctcaacgcat attaacacca acaatcccat ctggcagcag
    40501 gtcgatttaa ccgcaattgc gaagtccttc cctattccag tggtctttag caacaatgct
    40561 cactgtatga ttattgccaa gcgcttatac gagcgtcagg cacataatca caattttatt
    40621 ttctttcatg tcggacgagg catgcactgc tcctatatgt ataagggggt catttatagc
    40681 cgtcacaatg ctgttgttgg ggaaatcgga cataccattg tcaaccccac tggagagctt
    40741 tgtgaatgtg gcaaaaaagg ctgtttacag acctatgcca gcaatgcctg gttgctcaaa
    40801 aaagcaaaac tgctacatca gtatgccccc aattctcatc taagaagcct tgtcgataag
    40861 gcctgtgagc tcaagctaga ccatctcttg attgcctatg agcttggtga tgtcggggtg
    40921 accacgctca ttcacacagc tattgattac cttgttttat ccctgtctaa cctctcctta
    40981 ctgattgata ccgagcaaat ctatctccat ggcagattta tcagccatcc tcttatatcc
    41041 tccaaaattc tgcaagccct gcaaaatgac attaagcttc ttagcaatca aaaaaagcca
    41101 gaaatcattg tcatgccttt ttctgtctat aatgccgctg tgggagctac aggcttatgt
    41161 atagatgagc tttacctcaa ttataaaaac aaatatgatt gataaccccc acaccaatat
    41221 cagctaaagc tttaaagccc atttgagaag ctatttctca agtgggcttt tgcattatgc
    41281 gactttcagt ccatctcgct ccgcaggtgc gagacaaatg ataaccataa aaaaagagag
    41341 gcacttggtt ctctctgttc tatcctaatg ccccatttga aactcaccag caaaatactc
    41401 tgccagcatc agtctatgct tgtctgagat tgaagacagc tctgcaatct cttctctaga
    41461 aaaataaccg agccttaagg tttcatcatt ttgataatca gtgatagcct tatctgcctt
    41521 ggctataacc tcataaagca tcacaacggt ctgaacctta tcaccatttg gataggtctc
    41581 ttcaaaattg gtataaacat tcaacaaccg taaaggctct actgtaatcc ccgtctcctc
    41641 ataaaattca cgcctgcagg tttcagcaga agactcaccc agctccatgg cacctcccgg
    41701 aattgcccag gttttcttat ctgcacgtag ctgcaaaagc accttacctt cggcattggc
    41761 caaaatacca ccagcaaaag tcagaataat gttatcatgc cccacctttg agcgaatata
    41821 ggaaatatag tcctgtgtca tcgtaactcc cttcattgcc atcataagat taaagccagt
    41881 cagctggcgc aattgctgct tttttgccaa ccaataagca atgcaggctt tgtctcttgt
    41941 ccttgatagg ctggcaaagc atatagccct aatttttcaa cctgattata tcacactttt
    42001 taaaagccag aaagagactc gaatgccaag tcccttttct ttcaatctat aaccaacctc
    42061 agaaaaactc agacaagcta cgataacttt tttaatgtct tctttggcca atggtttgcg
    42121 actggtcatt gaattacttt caatattatc cccatcatca catgataacc acaaataaac
    42181 acgtacttgt gtcattgcct tctcctcaat cagtagtagg tacctactgt ttttttgatt
    42241 gattgtacct ataggtgttt ttttccttca aaatctttaa ataaaatacc ctttataa
//
LOCUS       DARYLD010000012        41302 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYLD010000012 DARYLD010000000
VERSION     DARYLD010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41302
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            400..813
                     /locus_tag="TU651_000537"
     CDS             400..813
                     /locus_tag="TU651_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0896562.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
     gene            1073..1654
                     /locus_tag="TU651_000538"
     CDS             1073..1654
                     /locus_tag="TU651_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL0896563.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            2064..2390
                     /locus_tag="TU651_000539"
                     /pseudo
     CDS             2064..2390
                     /locus_tag="TU651_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            2459..4462
                     /locus_tag="TU651_000540"
     CDS             2459..4462
                     /locus_tag="TU651_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896564.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            4459..5067
                     /locus_tag="TU651_000541"
     CDS             4459..5067
                     /locus_tag="TU651_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0896565.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(5256..7982)
                     /locus_tag="TU651_000542"
     CDS             complement(5256..7982)
                     /locus_tag="TU651_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL0896566.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(7997..9283)
                     /locus_tag="TU651_000543"
     CDS             complement(7997..9283)
                     /locus_tag="TU651_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL0896567.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            9416..10474
                     /locus_tag="TU651_000544"
     CDS             9416..10474
                     /locus_tag="TU651_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0896568.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            10489..12183
                     /locus_tag="TU651_000545"
     CDS             10489..12183
                     /locus_tag="TU651_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL0896569.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            12210..13601
                     /locus_tag="TU651_000546"
     CDS             12210..13601
                     /locus_tag="TU651_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0896570.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            13588..13725
                     /locus_tag="TU651_000547"
     CDS             13588..13725
                     /locus_tag="TU651_000547"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896571.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(13921..16095)
                     /locus_tag="TU651_000548"
     CDS             complement(13921..16095)
                     /locus_tag="TU651_000548"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL0896572.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(16083..16976)
                     /locus_tag="TU651_000549"
     CDS             complement(16083..16976)
                     /locus_tag="TU651_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0896573.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            17188..18138
                     /locus_tag="TU651_000550"
     CDS             17188..18138
                     /locus_tag="TU651_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0896574.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            18148..19074
                     /locus_tag="TU651_000551"
     CDS             18148..19074
                     /locus_tag="TU651_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL0896575.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            19158..20603
                     /locus_tag="TU651_000552"
     CDS             19158..20603
                     /locus_tag="TU651_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0896576.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            20951..21556
                     /locus_tag="TU651_000553"
     CDS             20951..21556
                     /locus_tag="TU651_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL0896577.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            21546..23270
                     /locus_tag="TU651_000554"
     CDS             21546..23270
                     /locus_tag="TU651_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0896578.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            23270..24754
                     /locus_tag="TU651_000555"
     CDS             23270..24754
                     /locus_tag="TU651_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0896579.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            24768..28211
                     /locus_tag="TU651_000556"
     CDS             24768..28211
                     /locus_tag="TU651_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL0896580.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            28362..29246
                     /locus_tag="TU651_000557"
     CDS             28362..29246
                     /locus_tag="TU651_000557"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL0896581.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            29372..30145
                     /locus_tag="TU651_000558"
     CDS             29372..30145
                     /locus_tag="TU651_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL0896582.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(30477..31559)
                     /locus_tag="TU651_000559"
     CDS             complement(30477..31559)
                     /locus_tag="TU651_000559"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL0896583.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(31618..32373)
                     /locus_tag="TU651_000560"
     CDS             complement(31618..32373)
                     /locus_tag="TU651_000560"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL0896584.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            32811..32981
                     /locus_tag="TU651_000561"
     CDS             32811..32981
                     /locus_tag="TU651_000561"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896585.1"
                     /translation="MLRYLKAILYLLAPRLAFSVTGVLFPDVFDNLFLVYNILMTLAF
                     WLAIYSVDLPEK"
     gene            33889..33959
                     /locus_tag="TU651_000562"
     tRNA            33889..33959
                     /locus_tag="TU651_000562"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33921..33923,aa:Thr,seq:ggt)
     gene            34487..34741
                     /locus_tag="TU651_000563"
     CDS             34487..34741
                     /locus_tag="TU651_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL0896586.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            34763..35263
                     /locus_tag="TU651_000564"
     CDS             34763..35263
                     /locus_tag="TU651_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0896587.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            35523..36107
                     /locus_tag="TU651_000565"
     CDS             35523..36107
                     /locus_tag="TU651_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896588.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            36307..36870
                     /locus_tag="TU651_000566"
     CDS             36307..36870
                     /locus_tag="TU651_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0896589.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            36883..39534
                     /locus_tag="TU651_000567"
     CDS             36883..39534
                     /locus_tag="TU651_000567"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL0896590.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            39629..39784
                     /locus_tag="TU651_000568"
     CDS             39629..39784
                     /locus_tag="TU651_000568"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896591.1"
                     /translation="MKKRVIGWLGVLVIGLMLGLIWWKWLVADRPLTQAGQGSHDHSS
                     DKGLSAA"
     gene            39747..40235
                     /locus_tag="TU651_000569"
     CDS             39747..40235
                     /locus_tag="TU651_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL0896592.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(40438..41238)
                     /locus_tag="TU651_000570"
     CDS             complement(40438..41238)
                     /locus_tag="TU651_000570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896593.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
BASE COUNT        11364 a         8286 c         9606 g        12046 t
ORIGIN      
        1 tggaaaggag tgctttcaaa tgttatcagg ggagcatgat ggctaaagag agacctcaga
       61 ggaaactcag tctttgaagc attaagacag ctttctcata ttggttacgg gtattagaaa
      121 tgcgcttaat cggtgtcaac agttttcgta ttaccattta agacgtttcg acgacatttt
      181 aagacttaaa tactgaaagc agctggtaat atgctatact ggtgccagtt gctaaacata
      241 ggaaatattc atgtggacga cagcattgat gaaatattta atgcttaggt actggtagac
      301 ttgcttatgt tgaggctgaa aaaattaata gagtttgtga cgcagctatt ggaggaatag
      361 gtggcgcact gacttgctaa gaaagggcaa ggtgttgtaa tgcttaataa aatgaagcga
      421 ctacattatt tgatgatttt taggctatta actggtcagc taccagctat tagcttgatg
      481 gctgttcttc tttcaaaaga cattcatagg ctttctttgg gatcactgat tagttttgct
      541 atctttgcgg taagcactgc tgcttctaat tactattttt cacgagaaat tgcgattgag
      601 cagttgaagg aacaaacacg tcccaatctg ttattaactc agatcctgtt tatagtggtg
      661 tttatgatta taggcattgt gtcaatctat tgtggtctaa gctcgtctga gttttataag
      721 caggttattg ctgtgatatg ctcttttata tcatttgtca ctatgggatt gatgatttgg
      781 gggatcagat acgcaaaagc ttatcgtcgt taatagcttg aggtggtact ggtacttgaa
      841 atcacctcct taaccagtta atcataagct atagcactag gtatcagcct taaagcgacg
      901 atacctagtg tttgtgtgct caaacgctta aaatagcttt tgagggggta gagctgtcta
      961 tctgcaagcg atatgacaac ctatttcatt tagggatcag gcttttttac tatcagtgtt
     1021 tttgacaagg cccttgtttt ggagtatact gggaaaacta ggagggctat taatgcgtag
     1081 gattcgttta gcaaccttag cagatgctaa ggctttactt gatatttacc gtccttatgt
     1141 tgaggaaacc gctgttacct tcgagtacac tgtacctagc ttgaccgagt ttgagcgacg
     1201 tctgtctgac attatggtct tttatccctg tctagtagtg gaagaggagg gaggcatttt
     1261 aggttatgcc tatgctagtc gctttcatgc acgcgcagcc tatgcttggt ctgctgaggt
     1321 gaccatttat ctggcccagg aggctagagg gagaggcttg ggatcagcct tgtatcaccg
     1381 tttggagggt tatctgaaag gtatgggaat cttaaattgt aatgcctgta tcgctagtac
     1441 agcgcatgct acgccttatc tgaccaatag cagtcaagtc ttccatgaaa aactcggtta
     1501 tcggttggtt ggcagatttc atcagtcggg ctataagttt aaccagtggt ttgatatgat
     1561 ttggatggag aaactgctgg gagagcatga cgtacgccct cgcccagtga tgtcatttag
     1621 ggattttctt tgccagaagc accagtctga atgacacctt ataaaagctt agattaatac
     1681 aaaaggatta ggtcctgtca gaggaagcta atttttttgt attgtttgac gagaagtttt
     1741 gactgataac cgcaatcata aaaaaactct tcaggccctg ttataaaatg gtggtagcag
     1801 gagatggtta tgtctgagct tgtcactagg tcagctacag cagtcctagt gtcatagctt
     1861 taaaaatgag aaaaaagaaa ttatttttta agcttggtct ttttaatatc tttttttgcc
     1921 cttgacaatt ctgccaatga gctgcaaaaa aacttaagct ctttcccaaa aagcttttat
     1981 gatatgatac acttgtgttg taaaaggatc ctgatactag ttaagatttt tttactttat
     2041 tttaacaaag gagagtacac gacatgaaaa gaagtgtaaa atggtttatg agccttggct
     2101 tggttggagc tttcgtagtt gctgggatat ctaatgttaa cgcagagact aggcaccctc
     2161 atccaaagta taaggacact tgggaatttg gaattaccag tgctagctga tcttactcaa
     2221 acgcttttct tggagttcct attgggctag gaagtagtgc ttctgtgaca gacttttggg
     2281 gaaatgtaaa tagtaaagat agtcaaaaca atggttgggc tcgtgccggt gtaaaaaagc
     2341 agtggaattg ggttcaagca aagtcatgtt atggctggta tcaggtttaa tgttttattg
     2401 tacgttttag tggatgaaga tattatcctc ttagtcaact tttctcaagg aggtttttat
     2461 gaggtggaga gctacagtta tctgtatttt cgttctgctt ttgacatgtt tatcatttgg
     2521 tgcggtcaag gagtatggca atgatatcaa ataccctgtt caggctgcat tttcattagt
     2581 ggcttcaaac aaagatgttg ataagggaca cgttttagac aggatcgaag ccttagccga
     2641 gcaggaacat atccaaattt atcgtcccta cttagatcat actggtaaag aagccaccta
     2701 cctgtttggg acaaatggga aaaagactgt ctatagcagt aatcgcaagg agctcttgac
     2761 aaacgatctt agtggcatgt actacacgac gaggtctctt ccttcatcat ttgaaaccgc
     2821 gatgactgaa cggggcttga cctacaaagg tgctgattta ccttggtatc tcttgcctta
     2881 ttattttttg ttcacaaact tacgatcctt agctatttgg accctctttt ttgtgtttgc
     2941 cctcctcttg tttgctgtta aattgatgta tgctaaaaag tctatgatac taagaagcct
     3001 gggcttattt gaacactata gccgcaagga gttgctacag gatttgttgc tgatgggagc
     3061 tagctttgcg gttagtattc tcctcttcat tctctatcaa ggcagtatct ccaatgtttt
     3121 tgtcaagtca tttacacttc tgatcttgac taatgctgtc attttattat tgctgatgct
     3181 tgctgttcat gctttatttt tcatcaatat ccgttcgttg aaggcgctag ccattctaaa
     3241 aaataaacaa gcaacccctt tggtcctctt tgtctggttg gtggggattt gtttgtctag
     3301 cgtcattttt gggctttccc tacacaaaag cttggagact ataggaaaat ctgccaatga
     3361 cattcaagtt ctaggaaaat gggataaagc taaggatttt gcggaaataa catggctaga
     3421 taccttgagt acgcatactg atgacaatca ccaaattgat agtgattatt tcaaggaaga
     3481 aaatcagcgc tatcaacatt ttctcctgtc tttttctgat aatgacgtta tttattcagc
     3541 actttcaagc cttaacgaaa ccaatttaca atcagctcct gatgacttca aaaaagagtt
     3601 aaagaccaat ggggttgatc caaggattgc gtcaaaagtc cgttatgtca atcagggatt
     3661 tatgctaaaa aataaagaca ttttccctaa caatgattac ggaaggccag cagctgatgc
     3721 tgtaggagtc atttatattt ctaaacatat gatgggagat gctgacagca ttttaaacat
     3781 tgtcaattat gaatggtttc aatatagcag cctaaaggct aatcaattgg ttgttcaaga
     3841 ggttcctgac ggacaaaaga gctttctgtt taatcataag caagaccaac aagacatttt
     3901 tgctcagcaa gaagaagtga atactatatt agtgcagtta aacttttcgt tcatgacgga
     3961 gccatcatta ttgacgaagt ttggagaaat ggctcaaaaa tctatctatc gtcaggcgct
     4021 tattcgtgat cgattaacac aagcaggctt gacgaatttc tctagtttga ccaatgtttc
     4081 caatcatttg attttagagc gccataaaat cctaagccag ctcatcggaa gtgttattgc
     4141 cttaacggtc cttgccattg cccagtgctt tatcatttat gaatacattg tttctctgat
     4201 gaaacaaaag gccaaaaaga tttccgtctg gttcttgatg gggcaaaaaa gccttgtttt
     4261 gattggtaga ttgttattgc ccttagcttt gtgtttgttt cttgccatag gaatgatggg
     4321 aatccttact ggaaataggc tcatggtact aggcattggc ctgctttatt taggagaaat
     4381 cgtttgtatg tccttttttg cttatcaggc tattttgaag catcggattc aaatcatcaa
     4441 aggagatttt gacatattat gattgagata aaacagcttt ccaaacatta tggaaaaaag
     4501 acaatttatg acaagcttag cttgactttt gaggccaatc gttcttatgc acttgtaggt
     4561 ccttcaggat caggcaagac caccctatta aatgctattg ctcgccttga aaagccagat
     4621 agtggtcaga ttttagtaaa tggtcaagac atttggagca tgaaagagca agattatttt
     4681 aaggattatt tgggctatgt ttttcaaaat tatgcactga tagaggaaga aacagtctat
     4741 gacaatctta aaatgctggc tcctaaatct aacattgtgg aagccttgca tagcgttggc
     4801 ttagacagta gttttctctc acagaacatt tatgaattat caggtggtca ggctcagcgt
     4861 gttgctattg cacgcctatt gttaaaaaag gcttgcatta ttttggcaga tgagccaacg
     4921 ggtgccttgg acaaggaaac aggtgatgag attattgagc tgttgcttag tttggtgagc
     4981 cctgatactg ttctgatttt tgccactcat gacccaaatg tgtttagccg cgttgatgac
     5041 atcatcgaca tctgtcatct acaatagagg caagctctga gacatttagt ctggactgtc
     5101 gagctacagc aattagcttg acaatgctgt tattcctttg tgtcaggaag agattgctat
     5161 tcttctatag atttttcgaa tagacaatgc tgaaagtcct tagcgttaat gctaaggact
     5221 tttttgtgat ttaggtcaag gtagtggtaa tctggttata gatgagctga ttcactcttt
     5281 ttccaagcta gggttaggat ttcgcccttg ccaagctcag ctggtagggg ttcatgctga
     5341 tcctcttcta gtaggctggt aacccttgct gtgtggtctg ggattgctag ggtaagagcg
     5401 caggccttgt catttgatac attatagctg cgcgtgatta gggcattatc ggataggcga
     5461 cgcttgaagg ctgtgagagc aacgtgatca gttgctcctt tgatgtaagc atattgagct
     5521 ggcagctggc cagaatgcct cttggtttgc gccatggtga ctggtacctg agcctcctga
     5581 gctcgccaat agctggcaaa gcgtgtggta gcgttaatgc tttcaaagct aaagctgaca
     5641 gtctgttgac cgaggcattg agcatcaggg gttgggaagt agccccaatc tccaagctca
     5701 ccgacgcttc gtaggagcgt gatagcgatg gtattggtat ctggtaggat ttcgtattca
     5761 ttgaggccgt aattgcctac agtgacacca gtcctaccat caaaaaggct gacaaaggcc
     5821 tcctgatgct gaggattggt tgggtttttc cagaattggg cattggtatg attaggccgc
     5881 tttacggttt caaaaatact atctgcaaaa tggtggtctg tctttaaatg ggttgggaat
     5941 agcacgcgca agcggtggtt tgtcatttga ttgttaaagc tggtctgaaa ttgtaggcgt
     6001 gggctgtctt tttccatacg aataactgtt gttactgtaa agggcgcttt ttcctgtgag
     6061 cgtttggcct gacgctctct aatgtcaatg acagcctcca tttcagcctt tagacgatca
     6121 tctgtagcta agggaatatc aaaggtctgt gtcaattcga tttcagcaag ataggctgtg
     6181 ttggtcaaga cccgcaactt acagctccct tgatgagcaa ggtaggggct atcatgatct
     6241 ggctggcgaa agatatattc gttaccaata tcaccacaat cctcgtattg gagacagctg
     6301 tcaaacctat tgccatttag cttgtcttca atcgttagaa ggccatttgc tgcgatgatg
     6361 acttttagga aatcattttc aagacagctc ctgtcctgat gaaagagcat tttgtcagtg
     6421 tcagttgctt ggcaaggctg atcagtctct tttagtgcaa gacattgcca tgacatagca
     6481 gaaagagtca gtgggagcct tagctgtacc ttgatggcaa agtaggcttc tctgaaggtg
     6541 cgctctggca gggcataatc aaaggcgatg tctgtgccta agatttcagc ctcctctatg
     6601 atcctgccag ctgcgtcaat aacctgaaat tgtggctgtc ttgtctctag gtattccttt
     6661 gcttcttgat aaacagcttt aggcagtcgt tgcccaaatg gaaaaatctt ccatgtcagg
     6721 gtgaggtcgg agaccgtttt tttctcatga ccgcaggtat tgaagaggac aaaaggacag
     6781 ctatcctctg gaaacatgga ggtatcaata gcctcagcta tttggttggc agaacgctct
     6841 gctaagtaag tccccacctc ataggcttta tcaaagcgag gcatcatctc ctggtggaca
     6901 ctatcaacac tacagccaca aatggagtca tgagggtggt tttgcatcaa tgttttccaa
     6961 gcatagcgca gctggtcgtg aggataggta cctgtgacct caaaggccat cgtggcaaga
     7021 ggctctgtga tattttcaag ctgacgagac actctggtat tagcctgctt gaggtaaatt
     7081 ctagcagagg cagtgttggc taaggtatac cagccgtccg tttcttggct ggtcatctca
     7141 ccagacacaa ttgagagctc ctcaggcagc tcctgactta aatcagccaa atagtcctca
     7201 aagcaagagt ggacaaagtc gtaatcaggg tagagcttat ttgcaagggc aattgccttg
     7261 gtaacgtcta gttgaacagg ctggtgatca accccattca tcatcagcag gtgcctggta
     7321 gaagcaaagc gctcagcgtc tgctagcttt tgatcccaga attgtcgagc ctttttctcc
     7381 tcggttggga tttcgttgcc attgctgtac caattggcaa ataataagcc gagaatgcgg
     7441 ctatcatcag gtccctgcca gatcatttca gaaaattggg agctgtattt ttcgcttgta
     7501 tccacttgat tgttaaagcc tgtaggcctg ataccacgtc caaaggcagc ggcatttagc
     7561 cctgcttttc gcattagctg tggtgtttgt cccatatttc cgaaggtgtc tggaaaataa
     7621 cccagtggaa cgcttgcccc ccattgctca cagtcctctt tgccaaccag catgtttcgg
     7681 acattggact cactgctggt caaaaaggcg tcctgtagga tataaaaggg gccaatacgt
     7741 agcttaccag cctgaatggc ctgtctaatc tcggcctcac gcccaggctt gacctgcaaa
     7801 tagtcatcta ggataatggt ttgcccatct agatggaagc tatgaaaatc agggtctgtt
     7861 ttaaaaaggt ctagtaaatc gtcaattaac tggatcaagc gcatgtggtg ctgctcataa
     7921 gccatgtacc attcgcgatc ccaatggctg tgtgaaatga tatgtacttt tttaggtgtc
     7981 atcactgact cactttctaa gggctaatgg taaagcccag ataatcaaga agaagctcac
     8041 aaaacatcat gtttgcccat gagaaccatt cacgtgtata gtgactcgga tcattgacgt
     8101 caaagccctc atgcatcagg tgggtgcctg cgtcagtagc caccagtaaa tcaagtatat
     8161 ctgctttatc tttttgatca agtgcagtta agccctgaag ggcaagtgca atatgccaaa
     8221 tatagtttgg tggcgtgtgg gaggagccaa taccagaagc agcactgcct tggtaataat
     8281 aaggattttc cgggcttaaa atggtttgac gagtggctag gtaaataggg tcgtccttgg
     8341 cacaaaagcc aagatagggt gccgcaagga ggcttggaat gttagcgtcg tccatgatag
     8401 tatagtgccc caggccatct acctcatagg catagatgat ctctccttgg ctgttggtta
     8461 caagagcatg ctcctcaatc cctttttgaa tggcaagcct aagtgcatga gctctcctag
     8521 caatcgtttg atccttaaag agatcagtat agagcccttc aagataggat aagacgacag
     8581 cagcaaacat gttggacggc acgaggtagc cgtattggca ggcatcatcg cttggtctaa
     8641 agccagacca agtcatgcct gtataggcaa caggagctcc cttaccgttg tgggtcaagg
     8701 tatcctcctt acgccaggtg tcgcgctcaa agctgtaagg agaggcagtg tggtcttgct
     8761 ctgtgctcca gacatcaagg atcagcttga ttcctctgtg gaaatcctca ttgaaatgct
     8821 ctgtacagtc tgtctctcgg tagagcagat aggctaactg gatcggatag cagagggaat
     8881 caatctcata ttttcgttcc caaatccaag gtcccatctg ggtgtggtct gcttggtggc
     8941 ccttgctatt ttcctcctcg ttaaaggcgt tggcataggg gtcaatgcaa atgtaacgga
     9001 actgacgttt aacgagacct gctatgattt gtctcatgcc agcatctgtc ttggctaaaa
     9061 agagataagg ctttagttgc gcagttgaat cacgcagcca catggcagga atatcacccg
     9121 ttagaagaaa gctggtccca tcttcgtcga tttttagggt cgtttccaag gtgttggcaa
     9181 agctggcttt aaaattaatg gcccagctac ggtgctcttc accgcagagc tcttcaatcg
     9241 tgtccataaa cctgagcaca ctgctaggaa taggtcttgt catatcatat cctcctaaaa
     9301 gatatatcat ttgatatctt ttttaattat aagatataac tttatttttg tctaccactt
     9361 tagaaaaggt ttacaagtct tttttttcgt gatatactgc tagagggagt aaaaaatgac
     9421 tgaattacta tataaaaaga tatatcattt tatcaaggaa caaattgatt cagggcaatt
     9481 acaggcaggt gaccgcctac caacagaaaa ggccctatca gagcaatttt cggtgagccg
     9541 cattacctct aagcgagcct tagtagagct ggagcaagag ggcttgatta cacgcagcag
     9601 aggtaagggc agctttgtga ccgatggccc accaccgtct actcagccta ataaggacat
     9661 tttgttgatc ctgccctttg cttctgatta cgaattggga gattatgcta aaggaatcat
     9721 gacggtcgtt gctgacaaag gctatcgcct gatggtccag cttacaagta cggtaagctt
     9781 ggaggagcta gctgattatg ctggtgtgat ttattatcca gaagacgtta atcatagtat
     9841 tgagctgctc ttttattgtg cccagcgtgg gcttgctctg gtgcttttgg ataaggcctt
     9901 agacctgttt gactttccag cagttgttgc agacaataag ggcggagcct atgagttgac
     9961 caagcatttg attgatcagg attgccgtcg gatcatgttt gtggcaactg cttcctttgg
    10021 tgaggtttcc tctgttagag atcgttattt gggttatttg gctgcgatgg cggaaacaga
    10081 gcttgaggcc aattattttg tgaagctgaa gtcagaaagc aatgctgctt atcttgagcg
    10141 attggttgat gagctgacgg ctgctacagc tgaaaagact ggtttagtgg ttgaaaatga
    10201 ttggctagcc attcaattga tccaaaaaat tctacaggtc gggctatcta ttcctgatca
    10261 ggtagctgtt gttggctttg acaacagcca agcctctcag ttaatcagcc ctcaattgac
    10321 aacagctgca caggattttt accagatggg gcagcaagca gcgcaactat tgatagagcg
    10381 gctgactcgg cctgatcagc agacggcgtc ttgtcagctt cctgttaagg tctttatcag
    10441 agaaagcagt caaaagtccc tagaaatgct ataaaaagga gaagtgtcat gtctatttat
    10501 caagccctca aggactatca ggaggtgata accagaggtg attacctcgt ttttgacgcc
    10561 cctgtttcct gtcgctttgt tggtcgtttt ttccgatttg agaaccaaac agctatgaag
    10621 cctagtctta cagcgtcagt ctatgtcaac tgggttgagg agggagcagc tgacttgacc
    10681 cttaagcacg tttttaaccg caccttagct agggatgcct ttaccttgac catttcagag
    10741 gataaggagc ttgtgattga aagccaaaat ttaagaggct ttcgctatgc tcaggaggct
    10801 ttagaaaagg taatgactgt taaagagggc aggctttatt tgccgattgt ttcggttagg
    10861 catagtccgt cctttgccat gcgtggtgtg attgaaggct tttatggcac cccttggacg
    10921 cgtgaggagc gtttagattg cttgagcttt attgctgata agggcatgaa tacctacatg
    10981 tatgccccta aaaatgatga ctatcagcgc agccactggc gtgagcccta tccagaggat
    11041 tgggtggctc attttaggga tctgatccag cttgccaagg aaagacaggt tgacttttgg
    11101 tacatgatta gtccggggct tgattttgac tacaccaagg aagaggacta tcagctgctc
    11161 tatcaaaaat tgcagcaatt gttggatttg ggtgtttgtc attttggcct gctgcttgat
    11221 gatattgatt accaaatagt ggcagcagtt gagagacgtt tcaaaaaaac agcctatgcc
    11281 caagcacatt tggcaacagc tgtttaccag tttttacagc ggcagcatgc agcccctgac
    11341 ttggttgtct gtccgacaga gtatgataat catcatgact ctctttattt agcagagtta
    11401 tcagaggcta ttcctgctga ggtggctttt ttctggactg gcccaagcac tctggccagt
    11461 cagatttctc aggcagatat tgagacaata gcagccatct accggcggcc cataatcatc
    11521 tgggataata tccctgtcaa tgattatcag gacgattcta agaggctctt tttgaccccg
    11581 tttgccaatc gctctccttt cttgtgtcag ccagactatc aggtcagggg gattgtgtct
    11641 aatccaatga ttagctggga actatcaaag ccgactttaa ttgatatgag tcgctacctg
    11701 tgggacgcca agcgttatca gccaagctat tcttggctag aggccttgag agactatact
    11761 ggagataagg ctatggcttt agcgcttttg cgctttgctt ggcataatgg caatcgtcat
    11821 ttgcacaggg atctcccctt tgaggtggag gaggccctta tgcgtaagga catagctagc
    11881 ttatctggtt gggtagctga gctggtagag ctggtggata agctgaaaga gcttgatatt
    11941 cctgcgtttc aacaggctat tgctccttgg tttgatcggg ctaaggctga tcagagcttt
    12001 tggagggtta ttttagagca agcgcctgat cttgagcagc aatatgctga gcttcaggag
    12061 caaaggcatc gaattggaag caatattcca agccgctttt atcagttgca ctatcttcag
    12121 gagaatagca tgctaggcaa tcaggcacag gtcgctgaag ctagagctga ggattatact
    12181 taattagttt ataagggaga acaagggaca tgctagagtt tccagaagga ttttggtggg
    12241 gaagtgctac atcaggccct caaagtgaag gctgctttca aaagccgcat cgcaatttat
    12301 ttgattattg gtatgagcaa aatcctgagc tgttttatga ttatgttgga cctgatacgg
    12361 cttctgattt ttttcatcag tatgatcaag acctagcttt attagcgtct ttgggtcaca
    12421 attcctatcg gacctctatc cagtggacac gcttaattga tgattttgag acagccacga
    12481 tcaatcccga tggactggct tactataaca gggtgattga tgcctgccta gcacatggta
    12541 tgcgtccggt gatcaatttg caccattttg atttgccaat tgctctttat cagaaatatg
    12601 gcggttggga atcaaagcat gttgtggatt tgtttgttgc ctttgctaga gtatgctttg
    12661 agcagtttgg cgatcgcgtt aaggattggt ttgtacacaa tgagcccatg gttgtggtgg
    12721 agggctcata cctgctgcaa ttccactacc ctgccattgt tgatgggaaa aaagcggtac
    12781 aggtggctta taatctagca cttgcaacgg ctaaggttat ctgtacctac caagaacaag
    12841 cagcagagct gagcaatggc agtgttggta ccattctcaa tctgacaccg atctatccgg
    12901 caactgattc agaggctgat cttgctgctg ctcatgttgc agagctgtgg cacaatgacc
    12961 tctttatgtc tgctgctgtt tacggtagct ttccaaagga gctggtagca atactacaaa
    13021 gagatggagt gctctggcag tccacaccag aggagctgga tcttatggct gcttatacgg
    13081 ttgattacgt gggcattaat ttttaccgcc ctaagcgcgt gaaggcgcca gaggttattc
    13141 ctgtgattag cccttcctgg agtcctgagt ggtattatga tgcctatctg atgccgcagc
    13201 gtcgtatgaa tgtggacaag ggctgggaga tttatccaga ggcggtctat gatattgctc
    13261 taaaaatgcg tgatcagtat aggaatatcc cttggttttt atctgaaaat ggggttggga
    13321 tttcaggaga ggatcgttac cgagatgaga gcggacagat tcaagacgac tatcgcattc
    13381 agtttttaaa agagcacctg acctatcttc ataaggggat tcaagcgggc tctaattgct
    13441 ttggctatca tgtttggaca cctattaatt gctggtcttg gctaaatgcc tataaaaacc
    13501 gttatggtct ggtagaaaat aatcaccgca ctcagcgtcg gcgtgtgaaa aaatcagggt
    13561 attggtttaa ggaggtggca gaggcaaatg gaattagcta agaaaagaag aaaaacacaa
    13621 aagccagccc aatctccttt aaagctaggt ttagagaagc taagagagat tttacaggag
    13681 cagctagtag ctttagcggt tttacctgct agggtgatgg gttagcataa gggcttgctg
    13741 atgagctatg ccagtgatag cgattaagga atgtaaaaga ggatttccta acatcataac
    13801 tatccgtcta acgggtgatt tattgtttcg tacctacgga gcgaaacgga ctaaagtcac
    13861 ataactaaaa gcatgtcatg gcttgctgta gtacgagtga tgacatgctt tttttagctt
    13921 ttaacgggtt agggagtagg gcaggtcctc agccgaatag tgcttgagtg ggggaactag
    13981 tcccagctga aagtcgagct gacagccctg aatcagatca tcatgattga tgtagagctt
    14041 gttgtagcta gcctgattga gcttgacctc tttgacaaat tggtattgag ggacattgcc
    14101 cctacagctg atttggatag tattgccatt tggcagataa agggttgcct gatctacagt
    14161 tggaatacca atcaggtatt gcccagttcc tggtgtaaca gggtaaaggc caaggctgtt
    14221 taacaggtac cacgcgctca tactgccatt gtcctcatct cctgggtagc ctgtatcggt
    14281 aaaggcatga ctgagcagat ttttaaggat tagctgactg tattgtggct gaccgatata
    14341 gtgatagaga taggggaggt gaaagcttgg ctgatttgag atagcaatct gaccaaaatc
    14401 ctgtgcggct agctcactca tttcgtggat ttcaaagcca tagctgtgaa cgtcaaacac
    14461 aggctcatga ttgcacagct cctcaagtct tttggcaatg gcggcgtttc ctccgatcag
    14521 tcgaatgtaa cctagaatat catgataaaa ggcaaatcca ttttgataat aggagccctc
    14581 ggtgtagtcc tgcccccagt ggatagggtt aaagccacat tgccattgcc cttgtcgatc
    14641 cttgcttttg aggtagccgg tatcagtatc gaccaaatgg cggtaattga gtgatcgcgt
    14701 gtggtattgg tcactaagtg ctgtcttgcc cagaagggca gctacctggc cgatacaaaa
    14761 atcactataa gcataatctt gagtctgatt gacgctttcc tggtagctat ttggcagata
    14821 gcctagctct tgatagtctt gattgccctt gcggccatag cctgttcctt gactgtctgt
    14881 attggcagtt gccagcatag cctctaaaag ctcaggcatc aggtcttttc tgatgccttt
    14941 gacagctcca tcagcaataa cagcatcaac caaggttcca ggcatcaggc ctcgctcatc
    15001 tggagacagc cattttggca gatagttggt gtcctgataa gctgacaaga gtccctctaa
    15061 aatatcagca taaatctcag gtgcaattag agacagcaaa ggatagacag atttataagt
    15121 atcccaaaag ccattgttgg tatagtattt tccagcaaca ggtctttgac ttgttgtatt
    15181 atagtgaatc gcctgcccgg ttgcagtgat ttcataccat ctttggggaa atagcagggc
    15241 tcggtaaaaa tgctggtagt aggccttgac cttatcaaag tctttatcct taatgtcaat
    15301 acgactgagg tagctgagcc actccttgcg gctgtattca aggctttttt caaatgatct
    15361 ggggaaatcc ctctgccaat tgagctgagc ttgatcaaag ctaataaaag aagcagccgc
    15421 cctaagctca agatgtttga ggtcatcagc aaattggaga taggtaaagg acgtcttgct
    15481 gcaatcatca agagatttgg agtttaagtc ttctccgata agctttttta gcacagggct
    15541 gctaaactga agataaacaa acatggctag gtctttatcc tgacagtctg tgatgttttg
    15601 cacacagcca aggattgttt taccatcagc tgtcacctgc caggagcttt ttccggggtt
    15661 atggataatc aagcctgctt tgccattatc aaaggaaaaa tcacaatgaa agctgtaggc
    15721 agctgctgtt gctcgcgtca aaatccgatg tctctggcta aaaatctcaa gaagatgagg
    15781 ccgaaaagct gcctccttgg gacgatagga ggtctgatta tgaaacacat ctcccttggt
    15841 cagcggtccg ctgactggaa gaaaagtaac cgtcgcaaaa tcaccgaccc aagggctggg
    15901 ttgatgtgtc aagcgaatac ctgaaaagct gtgatcatcg gggtgaaacc accaagcccc
    15961 tcgatcttga ctggtttcga cgcttagata atgcatgcca aagggaaccc ctgtcaatgg
    16021 caggcaattt ccctgtgaaa aatggtagtg attggttgtt ccaaagcggg tgtcaatgaa
    16081 gtctaatcga tccacatctc gtcctttcta tgctcttgca taaaatcaat agaggcacct
    16141 agtaggttgg cctcgttttt aaagtggcag atagcaagct gcggtctcaa atcagaaatg
    16201 ctgactatct gatagagctt atccagttca gcctcaaggg caggaagaag aaagtcagcc
    16261 tgagagacac cgccaccaat taggatcatt tcaggatcaa aggcatgctg gatattaaac
    16321 acccccattg ccagactttg aagaaagacc tgtctttcct ttagggccac aggatctcct
    16381 tgatcagcta gctctaagac ctctttaccg gtgtaacttt taccatcatt tatgatctga
    16441 ctatagcgct tggccatatt gaccacagtg cctaattcgc tgaaggtttg ataacgctca
    16501 ttcatgacca taaagccaaa ctcacctcca aataaatggg caccgtaatg aatcctgcca
    16561 ttaatcacta ggctacctcc aacaccggtg ccaagtacca gcatggcaag gctgctagtg
    16621 ccttgtcctg cacctagagc agattcggca agagcagcac agttggcatc attttcaatc
    16681 gaaaccggca gacctagtcg ctcctcaagg cattgctgaa tgggaaagcc atgaatataa
    16741 ggcagtgcac ttgctccctc gatgatacct gttgctttat tgacagctcc aggggagcta
    16801 atggcaattc ctgagagctt ttctgtgcgg tagtaagcca gtcgctcgtc aagcatatgg
    16861 taaaagtcct ctaggctttg gggagttggg cgactgcttt gcttttttag cctgcccttg
    16921 tgacaaatag caaatttgat gctggtgccg cctatgtcga tacataataa ggtcattgta
    16981 attcctccta taacaggtat attaccaatt agctaccctt agtatgacag attttgaagt
    17041 gcttgaaaag actttctcgg cattcctata ttttgtgcta tgatacctat aatttgtgtt
    17101 atcaaaccta taatttgttg cttgttctat gtgtaagcgc ttgatatact tgaagcatca
    17161 attgaaaagc aaagggaggt tgggaagatg acgacaaaga tcagcagcaa gaaatccttt
    17221 tggaaaaatg tgatcaaata ccgcgctttg ttgctgatgg tattaccggg atttgtctgg
    17281 ttcatctttt tcttttacat tccagtatta gctaatgtag tggcttttaa ggattttcat
    17341 tactcagcag gaggttttat ggaaagcctg aaagaaagtc cctgggttgg cttagataac
    17401 tttaaatacc tttttgcctc taaggatgct tggttgatta cgcgaaatac cattgcttat
    17461 aatcttattt ttttactatt taacgtcttt tttgccatcg ctttcgctat tatcatgagt
    17521 gagcttcgaa acaagaaggc tgttaaggtc tatcatacca tgtccttact gccttatttc
    17581 ttatcatggg ttgtgattga gtattttgtt tctgcctttt taaatacgga taagggcttt
    17641 attaatcagc tgctcattga tagcggcaat agcccaatca aatggtattc caatcccacc
    17701 tggtggccct tgattttact tttcatgagt gtttggaaag gacttggcta caacagtatc
    17761 atttattacg catcggttaa gggaatatca gacacctact atgaggcggc tatggttgat
    17821 ggtgccagta agtggcagca aattagacat atcaccattc cacagctttt gccgatgatg
    17881 tctatcctat tgattattaa tattgggagt atcttcaaat ctgactttgg cttgttttat
    17941 gtgattccta aaaattcagg tcctctttac gatgttacca gtgttttaga tacctatgtc
    18001 tacaatgccc tgacagctac tggtgatatt agtatggctt ctgcggccag tctttatcaa
    18061 tctgtggtcg gaacctgtat cctgctcatc accaatgctt ttgttcgtcg tatggatccc
    18121 gatgcagcct tattttagga ggaggacatg gagaaaaaga aaactgttaa aagggtcaac
    18181 gtcagaacct ttgacccaaa aaccaatgct gtctttaatg tgttaatcgc tctttttgcc
    18241 atctcttgta tcattccttt tatctttgtg atgattattt ccttcacaga tgaaagctat
    18301 ctgatcaatc atggctatag ctttttccca gctgcttggt cgacaaaggc ttatcattat
    18361 attttccaag gggctatgtc tcatcggatc ataagatcgt ttgcggtgtc tgtatttatc
    18421 accgttttag gaacctttat caataccaca atgacctcaa cctatgctta tgccatctca
    18481 agaccttatt ttccctacag gcgttttttt accatctatg ccttgatcac catgcttttt
    18541 gcaccgggta tggtagccaa ttatttggtg gtgagtaacc tgctgcaatt aaaggatacg
    18601 gtttgggcct tgattttacc gatggctctg ggaccctttg gcattttggt gatgaggacc
    18661 ttctttaaaa agaccgttcc tgatagtatt attgaatccg ctcgtatgga cggcgcaggt
    18721 gaattgatga tttttatgaa aatcgtttta cctttggcag ttcctgggat tgcaaccatt
    18781 agcctgttct cagccttaac ctattggaat gattggttca atgcgctgct ctatgtgcaa
    18841 agcgagagcc tttacccgat gcaatacctc ttgatgaaga ttcaaagcaa tatacaggca
    18901 ctagcccaaa atgctggcat gagcgcccag ctatctgata gcttagcctc tttaccaaag
    18961 gaatctgtcc gcatggctat tgttgtcatt gcaactttgc cgatcgccct aacctatcct
    19021 ttctttcaaa aatactttgt tggaggacta accatcggcg gggttaagga ataatcaccc
    19081 atttggaata ggtcatacag ctgaccgttc caatgattct gttatcaaaa aaagaaatta
    19141 ttttaggagg cttactgatg aaaaagtggc aaacaatctt atgtgtgacg ggagctgtgc
    19201 ttgcagctgc tagcttgaca gcctgtggaa gcaaatcagc ttctaaggac ggtgaggtga
    19261 agctattgat gtatcaggtg ggagataagc ctgataactt tgatgagctg atgacaattg
    19321 caaataaacg tattaaggaa aaaacagggg caacccttga tttgcaatac attggctggg
    19381 gtgattggga cgacaagatg aggatcatta ttgcgtcagg tgaaaattac gacattgcct
    19441 ttgccaacaa ttatgtggtc aatgctcaaa agggtgcctt tgctgatttg actaagctaa
    19501 tgccaaaata cgccaagaaa acctataaga acctagatcc ggcctacatt aaaggaaata
    19561 ccattgacgg taagctttat gcctttccag tagatgctaa cgtctatgct cagcaaatgc
    19621 tgtctttcaa caaagaattg gtagacaaat atggccttga catttcaaac atcaattcct
    19681 atgcagatgc tgaaaaggtc ttgaaacaat tccacgaaaa agaacctaat actgctgcct
    19741 ttgcgattgg tcaagtcttt agcatgtcag gtgactacga ttacccattg accaaaaatc
    19801 aaccatttgc tgttaaaatc gatgaaggca aaccaaccat cattaatcag tacgaagatg
    19861 agccctttaa agcaaaccta cgcttgatgc ataaatggta taaggaaggc ttgattccaa
    19921 cagatgcagc aaccaacaca gaaggctacc cgcttgaagg caatacctgg ttcatgcgtg
    19981 aagaaaccca aggtcctatg gactatggcg ataccatctt gaccaatgct gctggtaaag
    20041 acattgtgtc acgaccattg acaaagcctc ttaaaacgac ctcacaagcc caaatggcta
    20101 actttgtcgt gtcaaatgtg tctaaaaata aagaaaaggc cgttgaagtt ctttcccttc
    20161 ttaacagcga cccagaattg ctaaatggtc ttgtttatgg tgttgaaggc aaggcctggg
    20221 aaaaggttgg cgacaagaaa atcaagctgc ttgatggcta ccaacccaaa atgcacatgg
    20281 gtgcttggaa cactggtaac aacaagatcc tctacaccca agaatcgatc acagatgata
    20341 tgattgcaaa gcgtgaccaa tcaatcaaag acgctaaaga gtctccgatc ctaggcttta
    20401 cggtagatac caaggcaatc aaaacggagc tatcaaaaat ctcaaacgtg atgaaccgtt
    20461 ataaagctag tatcaatact ggtacagtag accctgatga agctcttcca aaacttcttt
    20521 cagaccttaa ggacgctggt tgggacaagg ttcaaaagga agtgcaaaag caattggacg
    20581 actttgttac aaaaaataaa taaggcaatg gactttcctt gcaaggtggt aagaactggg
    20641 gacagcctca gttcttttta gctcaagcag gcatacaaga gctgacagat aaggcctctc
    20701 ttagaaaaaa gccagagcct gcttgcaagg cagttggtcc accaaagccc ttgctgacaa
    20761 ggttttacca gccttagtcg gctgtcctct ttttattaag cttttgtcac aattagagta
    20821 aaatatgcta tattagaagt atctcatctt atcatcatga cagctaagac cttagtcatc
    20881 tggctgaggg atcgttgctt ctcttagggc gctattggtc ctacaaagga tactagaaaa
    20941 ggataatctt atgacaggaa ttgaaaaagc ctgctttctc atctggaaaa tgatgcagct
    21001 aacccttata tttcatttgc tttccttatg tggtgctgtg atttttggag tggggccagc
    21061 ttggcagacc attgttacct tgtttttgga gaccagtcag caggagaaac attattcgct
    21121 caagcgggcc tttcagatat ggcgtcgggt cttcaaagag gccaatctca gctttttctt
    21181 ctttggatta ttgctattat tgctgaatac gagcctgtac ttggccattc aatttcaatc
    21241 gctgctgtgg tttagcctat cctttattat catgtttgtc atggtttggc tggtgatgat
    21301 tgtgatttac atgacctttt atgcagtgac ctatgaaatt gctttttggg agaatctcaa
    21361 gctgtctttt atcagtattt tcttgaatgc caggcagttt ttgttgaccc ttgtggtttt
    21421 agctggagtt gcttggttta cttggcagta taagggcttg tatctttttc tgagctttgg
    21481 tgcgctggtt ttgttgctgg atatggtcac caagcctaat cgtcgcatgg tagatggagt
    21541 cattgatgac aagtaaatct ttaaagcggt tcttgatgga gcatattaag cagggctttt
    21601 taattaaccg cttgatgaaa atatatagcc tgtttatcgt ggctctcttt agcttaagtg
    21661 cggttggtct aagcacctat tcgattcgaa atacctacca aatggttgac aatcaaatgc
    21721 aaatgcggct agatgagacc ctagcaaggc tacaatctca aaactatatt accctgcgcg
    21781 tgctggagca gctgatcggg cgtccagagg attatcgaaa tctgtatcag tacatgatat
    21841 tgacccctaa tcaatatctt actaaggttt ttgaggattg gggtgagggc aaaaacacac
    21901 ctctgttttc agagcaggtc agaaggcttt ttgatttgta tccagattta gatgggctga
    21961 ccctgatgct ggacgatagc acgtcctatt tgtatgcaga taggtcgatt aagaccggcc
    22021 ggctcttatt tggtaagcct cagacgctaa agggcaatta cttagtaagg tccattcgcc
    22081 accctgagtc aggtgatgtt acaggccgcc tctatctgca ctttgcaagc cccagcacga
    22141 tgctacagcc tgagcagcat aagtatctag cgacctttgc ctttgattac tatggcagag
    22201 agctctttca tcagggaggc gctgcctttc cggagcttga agcaggtctt aaaaaggcgc
    22261 taaaggcgga tcaggctatt gatttgacag ctctcagcaa gagctatcat attcagtaca
    22321 atcgctcggg agacttgctg gcctatgtgg cggtcaaaag gtcttatttt atggaagagg
    22381 ctgtgcgtac aatgctcctg tatggccttg gctcgttatt gctagcttgg ttattgctac
    22441 agctcctttt cagggtattt cgcaattata tccgacaggt ctctgagatt acagatacta
    22501 ttgaaatggt tgcagctggt gatttgtcgt taaggattga caacagtcat atggaattag
    22561 agctgtatca catttctgag gcgatcaatc aaatgcttgg caacatcaat gcctacattt
    22621 tagaaatcta tgtccttgag gttgagcaaa gagatgccca gatgcgtgcc ttgtcatcac
    22681 aaatcaatcc tcattttttg tataacaccc tagaatatat tcgcatgtat gcgcttagct
    22741 gtcagcagga ggaattggca gatgtgattt atgcctttgc cgctttactt cgaaataaca
    22801 tcagccagga taaggtaacc actctaaaag aagagctggc tttttgtgaa aagtacatct
    22861 atctgtatca aatgcgctat ccagatagct ttgcctacca tgtcaagctt gatcctgtcg
    22921 tggctgatgt ggaaattcct aagtttatca ttcagccctt ggtggaaaat tattttgtgc
    22981 atgggattga ttacagccgc tatgataacg cccttagcat caaggcgcta gatgaggagg
    23041 acagtatttt gattcaggtg cttgataatg gcaagggtat tagccctgag cgcttagtgg
    23101 ctattgaaaa gggcttagag gagccgcaat cgacggggaa tagctctatt gggctgcaaa
    23161 atgtctatat gcgcctattt cacaaatatc gagacagagt gacttggtcc atgtctcagg
    23221 caccgactgg tggctttagg attcagatca gaattagaaa ggaagcttaa tgtacaaggt
    23281 cttattagtt gatgacgaat acatgatttt acagggccta aaggtgatta ttgactggca
    23341 ggcgcttggc tttgaggttg tggcaacggc aaggtcagcc aaagaagcct tagcttacct
    23401 agatgactgc gctgtagatg tcatgatttc agatgtcaat atgcctggta tgacaggcct
    23461 ggaattgatt gaggcagcaa gagatgtatt gccgcatttg cagaccttga ttttatcagg
    23521 ctatcaggaa ttttcctatg tgcaaagggc tatggagcta gagactaagg gctacctcct
    23581 aaagccagtt gataaaaaag agctggtagc taaaatgctc tattttaagg aatggcttga
    23641 tgagcagagg gcagcttctt tgcgtcaggc tgcttatcgt gagggcttga taaatctctg
    23701 gcttgctgat gaattgagtg agaaagagtt ttttcaacta acgcaggagc aacccgaggc
    23761 tgagctttta ggctttacgg tgttgtatgt ggattgcaag acttttagcc ctgccttaga
    23821 agcctttttt gaggcctcca agcagccctt ttacttaaaa aaggcagagc aaaagaaggt
    23881 ctatctagtc attctattag gacagagcca tcaggctaag cgctttacta atacgcttca
    23941 ggagcgattt tacaatacca tcaatcagat cattctagga gaaacggttg ttgattggga
    24001 aaatgtgtat gaaagctata atcaggtcag aaggagcttt ttttacaaca gcgaggtgtc
    24061 tcaggtagct gctaagacca acgctaaaat tgagctgccg gaatcgcgat tgcagttttt
    24121 ttcctttaac aagaccttga tgattgggga cgagccaact attgtctcca aattacaggc
    24181 aatctttgag gagatgacag agctaagctt ctctcctgag gacgtcaagc acgtctcttt
    24241 tctcttattt tcagacattt atcgccaatt tccgatttta gatcgaacga cctacctatc
    24301 gatggtcaag actattcacg atagtcagtc cattgatcag atcttatcag ccttaaaaaa
    24361 ggtgcttgag ctgacaagca aaagcaatca gccccaaaag cgctattctg atctggtcag
    24421 tgaagccatt acctgtattc aggaggaata ctctcaggaa ttaaccctca aggctgtgtc
    24481 agatcgcttg catatcaatg gggtttattt gggacaacgc tttaaaaatg aaacagagtg
    24541 tagtttttcc caatacctca atcaggtgag gatccaaaag gcacagcaat tgctgcttta
    24601 caccaataaa tcgattaacg aaattgccta tgagacaggc tataatacta accattattt
    24661 cataaaaatg ttcaaaaaat taaatggttt atcgcccaag gagtttagag accgttataa
    24721 agataattat caagctataa aaggaagcta ttaagaaagg gggcgctatg tctgtagaga
    24781 caatcactgg ttcaacggat caatctcatg gggatatcta tcagcttcac tggattgata
    24841 aagtagggcg ctgccatgcc ttttcaaagg ggtggcgctt tctgatggct gatttgcagc
    24901 tcgctcagga gccatttttt gatgattcgg actggcagca gatagcttta ccacatgatt
    24961 ttagcattaa tcagccctat acggttaatg gcgaagctca aagtgcctat aagctaggtg
    25021 gtgtaggctg gtaccggaag tattttgccc ttgatccaaa gctggctgac cataaggtct
    25081 atgtgacctt tgatggggct tatatggaaa cgcaggtata ccttaatggg catttgatag
    25141 gagagcatgt caatggctat caggccttta gctatgatct ctcagccttt gtaatccctg
    25201 ggcaagagaa tctattagcg gttcgggttg aacatctggt gcctagctcg cgttggtatt
    25261 ctggaagtgg gctttatcgg gaggcttttt tgaccgttct tccgaaggtt catcttgata
    25321 aggatcggct tcgtttatcc ttatcccagg cagcgcttga ggctgatagc caagcgcttg
    25381 agatagagct tggactcagc caacaggtcc ccttgagtgg ctatcagctt agccttagtc
    25441 tgtttgagca gctggcagat atccagcaga gacagacagt atatgagagt aaaccggtag
    25501 ccttggacct cttggaggag tcaggtaggc tggtgatgac cattcctctt aggcatatca
    25561 aactgtggtc gccagctcag ccccagctct atcagcttga tatgcttctt taccataagg
    25621 gagcagtgct tgatcggctg acacttgaaa caggctttcg acagctgcat tttgatgctg
    25681 agtgtggttt ctttttgaat ggcaaagcct ttaagctgca aggggtctgt cttcatcatg
    25741 atcagggtag cctgggggca tgtgcttatg aggaagctat agctaggcag cttgttttgc
    25801 taaaggaaat gggagcaaat acggttcgtg tcacgcacaa ccctagtgcc agaaggctta
    25861 aggatctggc taacaggctt gggttatttc tcattgagga agcctttgat acctggactt
    25921 atgctaaaaa cggtaatagc catgattttt caagccattt tcacaagaca gtgggacacc
    25981 aaaatgcagc caggctaaag ggagtcacta cagcagaaac cacctgggcg caatatagca
    26041 tacaggccat ggttctctca ggtcttcatg atccatctgt cttgatgtgg tcaatcggca
    26101 atgaattgtt agaaggcttc tcagctgatg tgagccacta cccttatgtt gctaaggagc
    26161 tatgccagtg gatcactgag ctggatcagt caagacctat tacccttggg gataataagc
    26221 tcaaggacaa gcattttcat tgggcgcagg aaacaaaagc gttggcagag caggtcaatc
    26281 agctccagtc cgtgcaagga gtgattggac ttaactatgc taaggccaga gattatgatc
    26341 gattgcatag ggacaacccg acttggctgc tttatggctc agagacagcc tctgctatta
    26401 atagtagagg ggtctatcat ctcaagggag gagctagtca ggatcatgag ctaacctcct
    26461 atgaccagtc aacggttgac tggggatcct tagctagtga ggcttggtat gatacaatca
    26521 caagggattt tgttgcaggt gagtgtgttt ggacgggctt tgattatcta ggggagccta
    26581 ctccttggaa caagattgac tcaggcgcag ctgatcagtg gccgtcgccc aagcaatcct
    26641 actttggtat tttagatact gctggatttg ctaaggatag ctattatttc taccaaagcc
    26701 aatggtcaaa agacaaaacg acacttcata tcctgcccag ctggcaggaa aaagaccttc
    26761 agctagatga tcagggcatg gtggaggttg tggtttatag taatgctgct agtgtgagaa
    26821 tactttttga tgatggtcat gggggccaga ttgattatgg catcaagacc ctgacaaggc
    26881 atgaaacacc agcaggccat tgctaccagc tatatgaggg tgacgatgca gcagaattac
    26941 ctcatcaaaa cctttacctg acatggaagc ttccttatcg ctcaggcagc ttgagagcta
    27001 ttgcttatga cgacaaggga caggtgctca cacagaccag cggtcgttcc tgtgtgagca
    27061 gctaccagca gcctgctcag ctttcctggt cctgctttga gcctcctaaa ctgcttgcag
    27121 agcctgcgct actttatctt gaattgtctt tgttagatgc taatgagacc ttggtgctca
    27181 gtgctaatcc tgtgattaag cttgaggttg agggtcctgg agcctgcctt gctctggata
    27241 atggcgatcc tcgtgaccat aggccctata ctgccttgtc acgccgagca tatggtggca
    27301 agctattagc cattattgct cttgatggtc gtgcgggtca gcttagaata acagctagag
    27361 ccgcaggatt cgtggaagcc agctatcagt tgacggtttc tgaagcagcc gttaatgaga
    27421 agcttttagc ctatcagctt gataaataca gctttatcac taatgagaca aataagccta
    27481 gcaagcccta tgcaaggtca agaggatcag ctgttgatag cttaatgcct aatcctgata
    27541 gctgcttaaa gcggcaaggc cattatctgc ctgataattc tgtaatggtt tttagctata
    27601 caacagcatt atcaaggcca ctgacctttc agccactgat caaaaggctg ctaaagggca
    27661 atgatatcat tctaccagac tggctgcagc ctagggcagc tgctggccag ttatttacca
    27721 aggcttttcc tattgattgg cagctaacag aggcagtttt ttctgaggag tcaagggtta
    27781 gtgggcagac cctttgtttt ggagaggctt tggagcttga agctatcctt aagtcagata
    27841 caaaaggatt aaggatcaat caagagctta gcttagttgc taaaaagaag cggctgtttc
    27901 agagtgatac ccagcttagc taccgctatc aatacgatac catacaggcc attggtgcca
    27961 ttagcctgac aggactaaag aagcccttaa gctcgcttag gcttgttttg gactatcgca
    28021 gcagcaccaa tgcgccatca aaacagctga tcctatcgct tgatcagata gaacagccct
    28081 gtcactacat catgctggaa gaagtagttg atgtgctaag cctggaccta acattagagc
    28141 agccgatcag acaggctttt gacttagcta ggcttcagct aggcctttgg agcatggttg
    28201 aggaggctta ggcttcaagc ttatcggctc atactgtcaa taggattgag ctgagacagt
    28261 ctttgaaaaa taaggtataa tgacagtaaa tgcctagcaa gctttgctag gttagcaaaa
    28321 aataagcatc gcctgatatg atgtaaagga ggaggtattt gatgctagag cgtttatcag
    28381 gtcagacacg attaacagct ttgctggcag caccggcacg tcacagccta tcaccgaaaa
    28441 tgcacaatgc agcttatgct aagctggggc tggattatgc ctacctagcc tttgaggttg
    28501 gtaatgctga gctagctgct gctgttcagg gcatgcgtgc cttgggtatt tgcggtgcaa
    28561 atgtgtccat gccaaataag caggccattg tcccattgct tgatgagcta tcaccggctg
    28621 cagccttagc tggagctgtt aatacggttg ttaataaaga tggcagaggt catcttgttg
    28681 gtcatatcac cgatggcaca ggtgctattc gagccttagc agaagaaggg gtctcgataa
    28741 aggatcagat cattacgatt gccggtgcag gcggtgcagg cacagccatt gctgttcaac
    28801 tgggacttga tggcgccaag gagattcgac tatttaatcg gaaaacagct acctttaagc
    28861 aggccaagca gctggttgct agaattaata cccaaacctc agccctggca agccttcagg
    28921 atttagcgga tgatcgagcc tttaggcggt ctatttcaga gtctagcatt tatattgacg
    28981 cgactggtgt aggcatgaag ccttttgagg agcatcgcct gattactgat ccagctctta
    29041 ttcgcccaga tcttgtggtt tttgaccttg tttatcaccc ggcagaaaca aagctcttag
    29101 cctttgcgcg tgagcatggg gctaaaaaag tgatgaatgg cctaggcatg ctcctttacc
    29161 aaggagcaga agcctttaag ctgatgacag gtgaagacat gccggtagcc tatatccgag
    29221 agcttttatg tcagaacaag gaatgaacgc ctgctgctca cgccggtata ggaaaaagaa
    29281 aaaaaggtta attgctcagc tctttgattg gtcttgaggt ttgtcggcat tttatttata
    29341 ataaaaagca ccaaaagcaa aggagcagcc tatgatattg acacaatttg accctgacta
    29401 ccaagctatc attaacccta aggaccttgt agcagaaata gatgactttc ctaaaacagt
    29461 agtcacctgc tttgcaagag caacctttaa tagggtactt aatgcactgc cacatcgact
    29521 gatagccaca acaagcgttg ctaatcttga tattccaata tacgaattag atgttaaagg
    29581 gcataagctt ggctttttca attcctacgt tggagcagct ggctgcgttg gggttttaga
    29641 ggatatcatt gctatgggaa tgaagcagct cttggttttt gggacctgtg gagtcttaga
    29701 cgctactatc agtgaaaact ctattattat tccaactagt gctattcgag acgaagggac
    29761 cagctaccac tatcagcctg ctagtcatga cattgcagtg aatcaagctt atttaacaag
    29821 ggctattgat gttttagaac agcattccca gacctatacc cttggtaaga cctggacaac
    29881 agatggcatt tatagagaaa ccagagacaa gatgattcaa cgaaagcagg aaggggctat
    29941 ttgtgttgac atggaatgct ctgcgattgc tgccctagca gctttcagac agctagagca
    30001 ttttcagttt ttttattccg ctgataatct agatgctgat gaatgggacg caagaagctt
    30061 agccaatgaa gcagacctag aagccaagga taacattgcc tttattgcct tagagttggc
    30121 cttacgatta tttaaggata attaaaaaag caccaagagc tatgaagtgc ctccaaaagg
    30181 ttagattaag gctctaacgc ctgggagatc agttcagctc aaggtgcttt ttaggtgtca
    30241 tgcagacagc tcacctctgc atgtcaatat aatgtttaga gtagcctatg cttcttatac
    30301 ctatgcctta gcattcacct agggacaaag caatgaagct taggcctttc accttactgt
    30361 gaaaaaagtg gtcttttctc atcaaaagac tcagtaaaca agaggctttg aagccttttt
    30421 gtttttcaga agcagcagtt ttttcactcg actaataaga caggagaaaa gccttctcag
    30481 gcgatatcta gcaggcttct tagccaatcc agcaggcgac tgtcatgctt agcaatagga
    30541 aagcttacat agccttttgt cgttggcaaa atgaggacaa tatgctgacc agaatttttc
    30601 ttatctgttt ttaaaacagt catcaaggct tcggctgtca ttgacttagc ctcaagtgtg
    30661 gtaggtagct gataagcctc aaaggcagcc tgtaatgcct ctaaatcctg ttggctcaat
    30721 agctgctgct ggacggccag cttggcctca aagaccatgc caatcgcaat agcctcacca
    30781 tgcctgtaaa gctcgtgatg gcataaggct tcaatcgcat gccctagcgt atgcccgaaa
    30841 tttaaggaca tgcggagatt gccttcaaat tcatcctttt caaccactct ttttttatgg
    30901 caaatcgctt gaaaaatcat ttgcctgagc tgctcttgat tgcggtcctt ggggaaggct
    30961 aggagctgtt gaaagagctt gcgatcatga ataaaaccaa ttttaatcat ttcgctgatg
    31021 ccgcaggcaa attctctttc agaaagcgtg tctaaaaact tggctgacac gataatctgg
    31081 tttggagggt agatactgcc tatcatattg gtcaagccct taaagtgaac cccaacctta
    31141 ccaccaatgc tgctgtctac ctgactaagt aaggttgttg gaatctgaac gtaggaaatc
    31201 ccgcggtaaa aggttgccgc aacaaatccc ccaagatctc caatcacccc tcctccaaca
    31261 gtaacaatga cgtccttttt agaaaaatta gccctaatca gtcgatcgta aatccgacta
    31321 acctcctcta gagacttaga ttgcccccct ggagcagcaa tatgaaggta actatcgtaa
    31381 tcctgttgaa aacgtctaaa taaaggctgg tataaatcaa ataccgtttg atcagtgata
    31441 aataatagct tgacgtctcc tttttcagca agaaattgat tcagcggctg aaaaatatcg
    31501 tctgtaaaga taatcggata gtcattgata cgagacttaa cctgaagtgt ttgtgtcatg
    31561 cgtctttctc tcctaagcac cattagttca aatgactgga cctgtggctg ctgttagtta
    31621 gctttcccaa agctcttttc caagctgctc tagctgttga taatcaatct gctgcgcggc
    31681 atctgacaag gcaagatcag gtgtagggtg cacctccatc ataataccat tggcaccgat
    31741 agccttagcg gccttagccg caggcaatag taaatctctt cttcctgttg agtgagagac
    31801 atcaacaatg attggcagct tcaccttttg ctgaataata gggactgcca tgatgtctag
    31861 catatttcta gtttccacat catagccacg aaccccacgc tcgcataaaa taatattttg
    31921 cttgccattt tcttgtaaat aagataaagc acccaaatat tcctcaatgg ttgccattag
    31981 tcctcgttta aacaagatag gcttgtcaat ctttgacaat acctttaaca gttcaaaatt
    32041 ttgcatattt cgagcgccaa tctgaataat atctaaatag tcataggctt cctctagctg
    32101 cctttcagac ataatctcac taacagcctt cagcgaaaat tcctggcaaa cctcatgtag
    32161 ataggtaacc cctgtcagcc ctaagccctg aaaggagtta gaagaggttc taggcttata
    32221 ggctccccct cgaaaatacc tgtagcctaa agccttggca cttgctgctg cctgtctgat
    32281 ttgctgataa gattcaatgg cacagggacc aacaataaag ttactctttt gacagccctt
    32341 gtttaaaaaa tcagctatta tatcgtttcc catttatact ctttcctaat atgatattga
    32401 gagaatgatt ccccaaaggt aagatgacag ctctgtctta gataatactg tgaataaggc
    32461 atgacagaac tattcatagc ttgggaaatc ataccataat caagcttaaa tttcaagcta
    32521 ataaagagag tgaccagctc gttgacaaag gagaagcttt tgagaatcct agccctctaa
    32581 ggtagagatt ttatggctat tagagctgtt gagaatgctt attagctgga ataggcaagc
    32641 atggtgggga agtgctgatg attgagtatc atgatgaggc tagttatagc ttttattgtg
    32701 ggagagttta gcttttcaaa tacaaaaaga aaaggtttac ctatatcgtt tttttggtgt
    32761 atatataata tatagaaagc aaactatttt agaaacagag gtaatggtag atgttaaggt
    32821 atttaaaagc gattttatat ctattggctc ccagattagc tttttcagta acaggtgtat
    32881 tatttcctga tgtttttgat aatttattct tggtttataa tattttaatg acacttgctt
    32941 tttggcttgc gatttattct gttgacctcc cagaaaaata gttgcgggac ttgtttagta
    33001 gttggttaac aaagggtaga tgatcagtta aaggtgaagc gtctgagcta tgttggccat
    33061 tatgcgtaca gctggcaaaa tgcttttgat ccaatcggtt aaacctcaag ctattctctt
    33121 tgggataaca aataccccat ctgtctcaga caaagaatgg caacgcctaa ataggattaa
    33181 catctgcaag tgctcttggg actgccaatg ctcttagtag cataggtgat ttttcagcgc
    33241 tagagacttt tcagcagatg agaaatagtc gcaataaacg aagacaaaaa gacttggctt
    33301 gagctcgtat ttggccttaa aatagtagtc agtcgagctt aaaaaaaagt cattgcagct
    33361 tatgaaggtt atcgtatcct tatttcaact gagctaggta agctagggag tttcctttag
    33421 gtgtaacgat agaagcgatc aaataattac ttcatttaaa gataaggatt gtaataagca
    33481 tagaaaagag cagttacttg acataactac tcaatgtaaa accgtttcag gcggtggctt
    33541 ttgttattag ataaaaaata atcgtcatca ttcggccaaa gttagaacgg ttatgtttta
    33601 tgctcatctt tgaagatgtt atagcacaag ccaataggga gactaaagct taaaaagagt
    33661 ttgagtagct tcaaaggctg ctagcttttt ggcctcctcc attttgttag ctgttgatga
    33721 atcgcccata ggcaccacca cccactcaga acgagcagcc acctgtctta atttttttac
    33781 tctaccactg tagcatgcca caagaaaaaa tcagaacact aatgacattt aaaaaaaaaa
    33841 aaaaaaagac ttgcacacca aaacaagtta tagtatcata gaaaggtagc cgctatagtt
    33901 aaatggtata ataaagcaat ggtaatgctt cgttccgagt tcgattctcg gtggtggcat
    33961 ctgagtactg tcctaagtct tattaggacg gtttttttat tgctaggtga accaatagta
    34021 gtcatctgtg aatcattacc atagtggctt ctgttcgccc aagcatagca aagctgctgt
    34081 cagaatgaac ccagccaaca atgtcaatag aagcagcacc agacaagcct ttagtcaccc
    34141 atgctttaaa gattttacgg ctgtaatgtt agtaactgtt acctgttttg ttcaagttgt
    34201 ctgtgacatc aaatcacttg atgctaccag tactgtcaat acattagctg tcacttggca
    34261 gttgttctga ctactactaa aaatagcagc tatcagcgtt gcaatcaaaa aagaatgcga
    34321 atcaagctct cctgatcagc ttaacttttt gaaagagttt gtacgggtca agcatcagca
    34381 agtcagactg ccttatttgt ttttatcata agcttctaag aaaatagcac aataagccag
    34441 gctgtggtat aatggtaagg attaagtcag aaagaggggg gcagacatgt cttatgagca
    34501 agactttttg agagattttg aagactgggt gaaggctcaa attcaggtca accagctagc
    34561 tatggcaacg agccggcaaa ttgcaaagga agataatgat caaagagcca gagatgcctt
    34621 tattcgttat gagagtaagc tagatgctta tgagttttta ttaggaaaat ttgataatta
    34681 taataaaggt aaagcttttc atgaggtgcc agacagccta tttggtagcc gtcattatta
    34741 gaggaaggga taagcagtaa tcatggcaag acgatacaat cgtaaaaaac aatacaagct
    34801 acagcttaag cgtcaaggac tgctcaaggc agtaatcaat caagtggagc agactgtgga
    34861 aaaggtggtt gataagacta aagaagcagt gcataccgct tcacaaatgg taacagcatc
    34921 aaagacagag actgctgatc tacaggataa gcagagcatt gctgaaaaag cagctcagcc
    34981 taaagcagat gtagcttcta gtagcttggc tgacagttct gaggtttcaa gtgaaaaaga
    35041 ggcctcaaag gctagcagtg aagtcttatc acgcgatgct tttgcagagt tggctgaggt
    35101 ttcagagctt cgggcagata ttgttacggt gctttttgag gctggtatta ggtcagctgc
    35161 tgcttttagc caatggacag aggcagagct tttggcgctt aagggaattg gaccagcgac
    35221 tatcagcaag ctaaaggaaa atggtgtcaa ctttaaaaag tagtctgatt tttattgctt
    35281 aataagtata aatttgttag aatgttagca atcagaggta tcttgagttt gtctgttaca
    35341 gagagcggtg gtgttgagaa atccgcacag atgtcaagtt atgtagctga ggcttacaat
    35401 ggaaaaatga taaagcagca gattaagtgt aatctgaaac agtggtggta ccgcggatta
    35461 ttagtgaatt cgtccctgtc tagtcgattg actaggcggg gttatttttt ggaggacttg
    35521 ctatgattga gataatgggt tctgttgaga ataatagatt accagatgtc aaaactagtc
    35581 gtttgctgct gcggcagcgt actttagctg atgttgaagc gatttttgct tatgctagcc
    35641 gacctgaggt tagttaccca gcaggctttc cacctgtgaa aacccttgaa gaagaggagc
    35701 attacatcgc aaacacgatg cctaagcgct ggcttttgca acagctgccg gcaggctatg
    35761 gcattgccct aaagggtgac aataggatta ttgggtctgt tgattttaac aaccgtcacg
    35821 cagatgatgt ctttgaaatg ggctatctgc tccaccctga ttattggcat caggggatta
    35881 tgactgaggc agcgagtgcc ctgctagagg ttgcctttac tctgcttaag cttcataagg
    35941 ttgaaatcag ctgttacgat tacaatatgg ggagtcgtcg gatcgcagaa aagctagact
    36001 tcactcttga ggcgaccatt cgtgatcgca aggacgctaa aggcaatcgc tgcgcagact
    36061 tgcgctatgg actgttgaaa agagaatggg agaggcagtg tagataagga gtagactctc
    36121 taaaatatgc gttaatctgt caaaagcatt tcataagaag tcctcaaact caaagcgctt
    36181 atgactacca aaactggtta gcgcttcgcc aaccagtgtc atcagtttct ggtagtctgc
    36241 cttgagcagc aagtgttatg ttaagtgagg tgagaagagg taagagagat cggaaagagg
    36301 tttggtatga atattatctt aattggagca caggcgtctg gtaagatgac aattggacag
    36361 gaattagaaa aactgactga cctgacttta tttcataatc atgaatcgat tgattttgtg
    36421 actaagttta taccaatgtc atcggaagct agagaactaa ttgatgagct acgattgcta
    36481 ttttttaaaa catttgcaaa acgtcagcaa tcaattattt ttactgttgt cattgatttt
    36541 aatgcacctg aagatatagc gtttttggaa acactacaga gtgtgtttca tgatttcgac
    36601 agagaggttt tattcgttga attagaaata gatttaaaag aacgcttaag gcgaaataaa
    36661 actgaaaatc gactttacca caaaccgata aagcgtcatt tggagtggtc tgagaaagat
    36721 attttggata ctgctaaatt tgctaacttt aaccctgcaa aggtaccaga aaatcttaaa
    36781 tattattgta aaatcaataa tacgagtctt tctgctcaag aaacagcgca gtttatcgtc
    36841 caaaaaatga aagagttaga agtaagctag aaaggacacc atatgtcaaa agaactttca
    36901 cccaaataca atccagctga ggttgaggct gggcgttatc aagcttggct ggaccaagat
    36961 gttttcaagc catcaggcga caagaaggct aagccgtatg ctatcgtgat tccaccgcca
    37021 aacgttacag ggaagctgca ccttggtcat gcttgggaca cgacccttca agatattatt
    37081 attcgtcaaa agcgcatgca gggctttgat actctctggt tgcctggtat ggatcatgca
    37141 ggtatcgcca ctcaggctaa ggtcgaggag cgcttgcgcg agcaggggat ttcccgttac
    37201 gatctcggtc gtgacaagtt cttagacaag gtttgggaat ggaaggacga gtatgcagca
    37261 accatcaagg agcagtgggg taagcttggg ctttcactag actatgcgcg agatcgcttc
    37321 actcttgatg aggggctctc aaaggctgtt cgcaaggttt ttgttgagct ttacaagaaa
    37381 ggctggattt accgcggtga gttcatcatc aactgggact cggcagctag gacagctctt
    37441 tcagatatcg aggttatcca taaggacgtt gagggtgcct tctaccacat gaactatatg
    37501 ctagaagatg gttcgcgcgc ccttcaagta gcaaccacac gtcctgaaac catgtttgga
    37561 gatgtggctg tcgctgtcaa tccagaagat cctcgttaca aggacttgat tggtcaacat
    37621 gttgttctgc caatcgtgaa taagctgatc ccaatcgttg gagacgagca tgcggatccg
    37681 gcattcggaa caggggttgt taaaatcaca ccagcccatg acccgaacga ctttgaggtt
    37741 ggtgggcgtc ataatctccc acaggttaat gtcatgaatg atgatggtac catgaatgag
    37801 cttgcaggtg aatttgcagg tatggatcga tttgaagctc gtaaggctgt tgtggctaag
    37861 ctagaagaaa tcggtgccct tgttgagatt gaaaagcgtg ttcattcagt aggtcattca
    37921 gagcgtacag gtgttgtggt tgagcctcgc ttgtcaacac agtggttcgt gaagatggac
    37981 caattggcta aaaatgctat tgccaaccaa gacacagatg acaaggttga cttctaccca
    38041 ccacgcttca acgatacctt cttgcaatgg atggaaaatg tccacgactg ggtaatctct
    38101 cgtcagcttt ggtggggaca tcagatccct gcatggtaca acgaagcagg tgacatgtat
    38161 gttggtgagg aagcgccagc aggtgatggc tggaagcagg acgaggatgt ccttgacacc
    38221 tggttcagct ctgcgctttg gccattttca actatgggct ggcctgatgt agactcagaa
    38281 gatttccaac gttacttccc aacgtcaaca ttggtaacag gttacgacat catcttcttc
    38341 tgggtgtctc gtatgatttt ccaatcgctt gaatttactg ggcgtaagcc tttctctaac
    38401 gttcttattc atggtctgat tcgtgacgaa gagggacgca agatgtctaa gtcgcttgga
    38461 aatggcattg atccaatgga cgttatcgaa aaatatggtg cagatagcct acgctggttc
    38521 ctatcaaatg gctcagcccc tggtcaggac gtgcgcttct cctatgaaaa aatggatgcg
    38581 tcctggaatt tcattaacaa gatttggaac atttcacgtt acattctcat gaataatgag
    38641 ggcttgacac ttgagcaagc aagtgcaaat gttgagcaag ttgcgtctgg cgctgctgga
    38701 aacgtgacag actgttggat cctccacaat ctcaatgaaa caatcggtaa ggtcacagag
    38761 aactttgata agtttgagtt cggtgtggca ggtcatatcc tctacaattt tatctgggaa
    38821 gaatttgcca actggtatgt ggagctgacc aaggaggttc tgtacagcga caacgaagac
    38881 gagaaggtta tcactcgctc tgttctcctc tacacgctgg ataaaatcct gcgtctcctt
    38941 cacccaatca tgccgtttgt gacggaagaa atctttggtc aatacgctga aggttctatc
    39001 gtgacagcgg actatccaac ggttgatcct gcttttgaaa atgaagctgc gcacaaaggc
    39061 gtggaaagtt tgaaggactt gattcgtacg gtgcgaaatg cgcgtgcgga ggttaatgta
    39121 gcaccaagta aaccaatcac tatccttgtc aaaacaagcg atagcgacct ggaagccttc
    39181 ttcaacagca atgtcaacta catcaaacgc ttcacaaatc cagagaggct taagattgct
    39241 tcaagcattg tgactcctga gttggccatg tcggctgtta ttacaggtgc agaaatcttc
    39301 cttcccctag ctgatctgct caatgtcaca gaagaattag ctcgccttga aaaagaatta
    39361 gctaagtggc aaaaagagct tgacctggtc agtaaaaagc tcagcaatga acgcttcgtt
    39421 gctaatgcca agccagaagt cgttcaaaaa gaacgcgaca aacaggctga ttaccaagct
    39481 aaatacgatg caaccgtaga gcgcatcaag gaaatggaga agttagtaag gtaggatagt
    39541 gatcatctaa gagccaattg gctctttttt tgatatactg tcaaggagta atcatcacaa
    39601 ttatctatat aagtcaaagg agtgtctcat gaaaaaaaga gtcattggtt ggttaggtgt
    39661 gctggtaata gggcttatgc ttggtctgat atggtggaaa tggttagtgg cagatcggcc
    39721 actaacccaa gcaggtcaag gaagtcatga ccacagcagc gacaaaggcc tcagtgccgc
    39781 ataaggaaaa aatggaatca aaagagcctg agacatcaca tcagccagaa gcctatcctg
    39841 atcttgctag ctatcaggaa ttggctgttc atgtgtcgat tgcagaccaa gtcatgacca
    39901 ttataggaga tggtaaggtt atttttaaga ccagcgtgtc aacaggagca aaggaaagtc
    39961 caacaccgac agggaccttt gtcattgagc ctgagcgagg agactttttc ttcaatcagg
    40021 catcagaaga gggagcttat tattgggtgt cctttaagga ccatgggatt tatctgtttc
    40081 acagcctacc aacagaccaa tatggcaatg agattccaga ggaggcagag agactgggac
    40141 agccagcctc acatggctgt gtccgcatga gcagagcaga cgccaaatgg ttttatgaca
    40201 atatcccaga aggcatcagc gtcacaatag aatagcccta atctccctca gaatagcctg
    40261 agcagataga ggaagagcct gttaatatta gcaggctttt aaagctcctt aaaaggctgc
    40321 aaaaaggaac gaaaaaagac ctgaaacagg tccattgatc taagagaaga caagtaacta
    40381 gccttctagc aaagtgtttt aaaaatgcgt tagtttagta gcttcgtgat aatacaatta
    40441 ataatattta tttaaaaaaa ctgtaaattt cgaccactgt tcctggattt tttcatttaa
    40501 acgtttatgc catgacttat gagcattctc tctaatttct tttaggtata tattttctac
    40561 tacccttttt tgactatgtt ctcgctcttt ttttatttgc tgtcttaaat tctcttgttt
    40621 tttctgttct tctaactctt tttgagcttt cttctgttct tgctctatta tgtcttgagg
    40681 tttagattct cctacaatcc atatttctga acctaagaca aaaccatctg aggtaatatg
    40741 aactctaaat ttatcaccat tagaagcaat tttattatat ggaacatatg tttcttcttt
    40801 ggaatttgtt ttttgtgttc tcgctgattc taaagagaac acaatttttc catcccactt
    40861 tgcaattgga tagtaccggt tatttgttaa gtcaccattg cttttttttt ggacttgtac
    40921 taattcagtt tccttatcat cttcttcgac tttaaatatt ctaatcaaag atcctggact
    40981 agtttttact actatttctt tgtcattatt tttgattggt ttaacgccaa agtctcgagc
    41041 gttttcccaa tctcttctaa atcctattac cttttggtca ccaatttgtg gtgcttctgt
    41101 ataatcatca taaccataat agccttgccc taaaactgga gaattttcat aatcactatt
    41161 tgcacttact tcgttgaaac atattaaact tagtaaaggt aaattaacga ttaaactcat
    41221 cactaacttc ttcttcattt tttcttccta acctccatta cttatgttta tttaataata
    41281 gctagggtta gtataaatga ga
//
LOCUS       DARYLD010000013        39075 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYLD010000013 DARYLD010000000
VERSION     DARYLD010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39075
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            110..637
                     /locus_tag="TU651_000571"
     CDS             110..637
                     /locus_tag="TU651_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL0896594.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TU651_000572"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TU651_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL0896595.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TU651_000573"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TU651_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL0896596.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TU651_000574"
     CDS             2207..2839
                     /locus_tag="TU651_000574"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL0896597.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TU651_000575"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TU651_000575"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL0896598.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TU651_000576"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TU651_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL0896599.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TU651_000577"
     CDS             3914..4657
                     /locus_tag="TU651_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0896600.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TU651_000578"
     CDS             4767..5867
                     /locus_tag="TU651_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL0896601.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TU651_000579"
     CDS             6223..6930
                     /locus_tag="TU651_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL0896602.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TU651_000580"
     CDS             7071..7787
                     /locus_tag="TU651_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0896603.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTTPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TU651_000581"
     CDS             8009..8854
                     /locus_tag="TU651_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0896604.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TU651_000582"
     CDS             9226..10071
                     /locus_tag="TU651_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0896605.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TU651_000583"
     CDS             10149..11519
                     /locus_tag="TU651_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL0896606.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TU651_000584"
     CDS             11512..12576
                     /locus_tag="TU651_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL0896607.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TU651_000585"
     CDS             12577..13269
                     /locus_tag="TU651_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896608.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU651_000586"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TU651_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL0896609.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TU651_000587"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TU651_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL0896610.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TU651_000588"
     CDS             complement(16695..17369)
                     /locus_tag="TU651_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL0896611.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TU651_000589"
     CDS             complement(17379..18755)
                     /locus_tag="TU651_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL0896612.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TU651_000590"
     CDS             complement(19278..19991)
                     /gene="rsmG"
                     /locus_tag="TU651_000590"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL0896613.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKKPL"
     gene            20127..20684
                     /locus_tag="TU651_000591"
     CDS             20127..20684
                     /locus_tag="TU651_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL0896614.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20721..21614
                     /gene="htpX"
                     /locus_tag="TU651_000592"
     CDS             20721..21614
                     /gene="htpX"
                     /locus_tag="TU651_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL0896615.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21902..22435
                     /locus_tag="TU651_000593"
     CDS             21902..22435
                     /locus_tag="TU651_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL0896616.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22620..23306
                     /gene="covR"
                     /locus_tag="TU651_000594"
                     /gene_synonym="csrR"
     CDS             22620..23306
                     /gene="covR"
                     /locus_tag="TU651_000594"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL0896617.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23310..24800
                     /locus_tag="TU651_000595"
     CDS             23310..24800
                     /locus_tag="TU651_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL0896618.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24991..25485
                     /gene="nrdR"
                     /locus_tag="TU651_000596"
     CDS             24991..25485
                     /gene="nrdR"
                     /locus_tag="TU651_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL0896619.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25469..26632
                     /locus_tag="TU651_000597"
     CDS             25469..26632
                     /locus_tag="TU651_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL0896620.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26633..27541
                     /gene="dnaI"
                     /locus_tag="TU651_000598"
     CDS             26633..27541
                     /gene="dnaI"
                     /locus_tag="TU651_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL0896621.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27591..28901
                     /gene="der"
                     /locus_tag="TU651_000599"
     CDS             27591..28901
                     /gene="der"
                     /locus_tag="TU651_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL0896622.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29242..32334
                     /locus_tag="TU651_000600"
     CDS             29242..32334
                     /locus_tag="TU651_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0896623.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32538..33131
                     /locus_tag="TU651_000601"
     CDS             32538..33131
                     /locus_tag="TU651_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896624.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33175..34506
                     /locus_tag="TU651_000602"
     CDS             33175..34506
                     /locus_tag="TU651_000602"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL0896625.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34554..35036
                     /locus_tag="TU651_000603"
     CDS             34554..35036
                     /locus_tag="TU651_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896626.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35145..36719
                     /gene="mltG"
                     /locus_tag="TU651_000604"
     CDS             35145..36719
                     /gene="mltG"
                     /locus_tag="TU651_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL0896627.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36792..37274
                     /gene="greA"
                     /locus_tag="TU651_000605"
     CDS             36792..37274
                     /gene="greA"
                     /locus_tag="TU651_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL0896628.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TU651_000606"
     CDS             complement(37515..38435)
                     /gene="yidC"
                     /locus_tag="TU651_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0896629.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38518..38796)
                     /locus_tag="TU651_000607"
     CDS             complement(38518..38796)
                     /locus_tag="TU651_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL0896630.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
BASE COUNT        11291 a         7214 c         9220 g        11350 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacaacac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt ttattaggaa taccggcttt tcgagggtac
    19321 ttgtttggcg tttccttttt cttttcgaca agagtgatat agcggccatc tccattagga
    19381 agttggtagg gctggtgatc aagcacctta gcaaaaagta gctgaagtgc ctttttagct
    19441 tcttctaatt cttggtccgc tgcttgtgcc tttaaagcaa tcagttttcc cttgattttt
    19501 aaaaaaggaa tggtcaactc agacagaatc tgcatgcggg caacagctct agcagttacc
    19561 aaatcaaatt ggccacgaaa ttgcttgtct tgtccaaaat cctctgccct accatgatag
    19621 aaatgtactc cctctaatcc tagctcttta gcaaggagct gaagaaaatg tatgcgctta
    19681 ttgagagaat caataatggt aacatcaagc tttggaaaca taattttcat aggaatgctt
    19741 gggaagcctg ctccagcccc aatatctaac agcctgagag gctcatttgg aatatatccc
    19801 tgtaaaagcg gagcaacaga gtcataaaag tgcttgagat agacttcatt ttcttcagtg
    19861 atggctgtta agttgatctt acggttccaa tcaaccaaaa gcttaaaata agtgtcgaat
    19921 tgttcttttt gatgatttgt cagagcaaat cctgcttgct ccaggacaag gtaaaaggct
    19981 tggggtgtca tatatatcct ctgtttttaa ttaattgcta ctattttagc ataaaatagc
    20041 agaaaactgc tgaaaagtcc cttcaatact tgctattaaa ctgaaaattg ctataattga
    20101 gacacaaaga ttaaaggaga attacaatgc caatgttttt agtaatagta gcccttatcg
    20161 gtgtgctggt tgtttggctg atggttagct ataatggcct ggttaaagct cgtatgcata
    20221 caaaagaagc ttggagtcag attgacgtgc agctaaagcg tcgcaatgac ttgattccaa
    20281 accttgttga gacggtcaaa ggctatgcta atcatgaaga gaaaacctta gaaaagatta
    20341 ctagtcttag atcacgtgtg gctgatgcta ctacaccgca ggccacaatg gcagcctcca
    20401 atgaattgag caagcaggtc actagcctct ttgcagttgc agagagctat ccagacttaa
    20461 aggccaatag taatttccta aaattgcaag aggaattaac caatacagaa aataaaattt
    20521 cttattcgcg tcaattattt aatacaacaa catcgcatta taaccttaag ctagaaagct
    20581 ttccgagcaa tcttgtggct aaattgtttg gcttcaagcc aagtgagttt ttacaggttc
    20641 ctgaagctga aaaagaggtt ccaaaggtag actttaccgt ctagtctaat gcggctaatc
    20701 aaggtcagaa gaggacatca atgctttatc aacaaatttc acaaaataaa cgacgaactg
    20761 ttatcctgct ttttgccttt tttgtcttac tggtagtgat tggcgctgct gctgggtatt
    20821 tactggctga cagctaccag ctgggggctg cttttgctct gattattggt gctatttatg
    20881 cctttagcat gatttttcag tcaaccagcc tcgttatggg aatgaataag gctaaggaaa
    20941 tcacagtaaa cgatgctcct gatttctttc atattgttga ggatatggct ctggttgctc
    21001 agattccaat gccaagagta tttatcattg atgatccctc actaaacgcc tttgccacag
    21061 gctccagccc tcaaaatgca gctgttgcgg caaccactgg tctactaaag gtgatgaatc
    21121 gtgaggagtt agaagcagtg attgggcatg aagtcagcca tattcgtaat tatgatattc
    21181 ggatatccac tattgcagtt gctttagcta gtgctgtcac actgatttcc agcattgggg
    21241 ggcgtatgat gtggtatagc ggtggcagga gacgtgataa cgatcgcaac gataatggct
    21301 ttggcgctat tatgctgatt ttctcaatct tgtcactgat cttggctcct cttgcggcct
    21361 ctctggttca attagccatt tctcgtcaaa gagagtatct ggcagatgcc agctctgtcg
    21421 cgttaaccag aaatccagag ggcatgatta gggctctaca aaagctaagc aattcacagc
    21481 ctatgactca tccagtagat gatgctagcg cagccttata catcaatgag cctagaaaaa
    21541 aagaaaagct tagcgcttta tttagtaccc atccgccgat tgaagataga attgaacgct
    21601 tgaagcatat gtgagagctt gagactagct cagctctcat ttttactagc cataatgttc
    21661 agaaaacatc attaattaat tgttttgacc cggacatttt ttaagacttt tatggaaatt
    21721 tgggctattt tcataggggt tttatggtta aacatttgat tgttggcttg tcaatactta
    21781 tttgtatcca gacttaatgt taaaaaaagt tatgaatttg tcataaagct attgacaaat
    21841 tcttgatatc atagtaaaaa tagattagag ttttattagg aagtgtttta taggagaaag
    21901 catgttatct gtttcagata ttagaaagcg accggaaggc attcgctttg agagagagta
    21961 cgatgttaag gaagcgctgc ttatacgtga tccgcaggtt atagatatta ataacgtcag
    22021 agcttcgggg agagctcagt ttgatgacgg cttgtatcta ttagagtatc agctgggcta
    22081 tcagattacc ctgccctcga gccgttccat ggcgcctgtt gtcttagatg agatgcagac
    22141 ggttcaggag ctgtttatcg aggaagcaga tgtggcaagt aagcaggaaa tggttgatga
    22201 aaaccttgtc ttagtcttat cagaggatca gcttgacctt gaagagagta ttattgacaa
    22261 tattttgttg gcgattccct tgcaggtatt gacagaggct gaaaaggagt cacaaatctt
    22321 gccgacaggg gaggattggg cagtcttaac tgaggagcaa taccaggccc agcagaagga
    22381 aaaagcaaaa gacaacagtc cttttgcggg cttacagggt ctttttgatg agtaaaaata
    22441 aaaattaaag atgtctgtat tttttatttg aaaaaagaac agttgtctgg tatactttat
    22501 aaatatacgg catattagtc attttgatga ctaaatagca atacttgatt aatacaaaat
    22561 ggatgaatct tgtacatagc tgataagggg ctgtgataca ggaagtaagg attggtgtaa
    22621 tgacaaagaa aattttaatt atcgaagatg aaaagaatct tgcaagattt gtttcgcttg
    22681 agctacagca tgagggttac gaggtgaccg tcgaggttaa tggtcgtgag ggcttggaga
    22741 cagccctaga gaaggacttt gacttaatcc ttcttgattt gatgcttcct gagatggacg
    22801 gatttgaagt gacacgtcga ttgcaaacag aaaaaacgac ttacatcatg atgatgactg
    22861 cgcgtgactc tattatggac gttgtagctg gcttggatcg tggtgctgac gattacatcg
    22921 tgaagccatt tgccattgag gaattgctgg cgcgtattcg tgctatcttc cgtcgtcagg
    22981 acattgagtc agagaaaaag actcctagtc aaggcgttta ccgcgactta gtcttaaacc
    23041 ctcaaaaccg ctctgtcaat cgcggtgatg acgagatttc actgactaag cgtgaatatg
    23101 acctgcttaa tattttgatg acaaacatga atcgtgtcat gactcgtgag gagctcttgt
    23161 ctaacgtttg gaaatatgac gaggctgttg aaactaacgt tgttgatgtt tatattcgtt
    23221 accttcgtgg gaagatcgat atccctggga aagagtctta cattcaaact gttcgtggaa
    23281 tgggttatgt gattcgcgag aaataattga tggcaaagca gaaaaaatat aagaaaacgt
    23341 taccaaaacg tttatcgaat cttttgttcg ttctcttctt ttgcattttc tctgccttta
    23401 ccctactcgc ttatatttca acaaactact ttttgttgaa acgagaaaag caaactattt
    23461 ttcaggctgt taacattgtt agagttcgtc tctctgaggt ggactctaat tttacgttag
    23521 agaatttagc agaggttctc tataaaaatg acagaacgca tttaaagatt gatgacgcaa
    23581 atggtagtcg tattatcaga agtgaacgaa atatcaccaa cacgctcaat gccaatgagg
    23641 atatctatgt ctacaatgtt gataagcaaa tgatcttcac aacagatgac gaagaggcct
    23701 cgccaggctt aaatggaact attggtaagg taaccaagga ccacattgag gagcaataca
    23761 agggcttttc aatgactcag aaggtctact ctaataagac agggaagttt gtaggctatg
    23821 ttcaggtttt ccatgacttg gaaaactact acatgatcag agcacgcctc ttcttttggc
    23881 ttttggtggt tgagctcttt ggggttggtc tggcgtattt cattatctta attgtcacac
    23941 gcaacttctt gaagcctctg aacaatcttc atgatgtgat gcggacaatt tccaaaaatc
    24001 cagataatct gatgctgcgc tcgggtattt cctcgggtga tgaaattgag gaattgtccg
    24061 ttatttttga taaaatgctt gataagattg agacgcatac acgattgcaa tcaagattta
    24121 ttagtgacgt cagtcatgag ctgcgcacgc cagttgccat tatcaagggg catattggat
    24181 tattgcagcg ctggggcaag gacgatagtg ctattttaga tgaaagcctc actgcagctg
    24241 cgcaagaggt tgaccgaatg gctattatga tcaatgacat gcttgatatg atccgagtac
    24301 aggggtcctt tgaagggcat caaaatgata caactgtttt agagagctct attgagaccg
    24361 ttgttggtaa ttttagggtc ctgcgtgagg attttgattt tacctggtac tctgaaaatc
    24421 aaagaaccct agccaagatt tataaaaatc attttgagca ggctctgatg attttgatag
    24481 ataatgcggt caagtattct aggaaggaaa agaaaatcgt catagaatta gcggttaatg
    24541 ctagcaatga agctgtggtt aaggtcaaag acagaggtga ggggatctca gaagaggata
    24601 ttaagcatat ttttgagcgc ttctaccgca ccgataggtc cagaaatcga accagcaccc
    24661 aagcaggtct tgggattggc ttatccattt taaagcaaat tgttgatggc tatcatttac
    24721 atatggaggt tgagagtgag ctaaataaag ggtcggtctt tattttgcgg attcccttag
    24781 ctgatcatca aggctcatag ctgtatacct gcctgagtat ctagtagatg ctcaggcttt
    24841 tgactgttct aatgtgtggt gtgatgatga ggtgtttatc agggaaggag ggctcttgga
    24901 ggtaaacctg agtgcttgtc tattcttttg ttatccctaa aattatggta aaatagggta
    24961 ttagattaac gatagaattg gggtgtttgc gtgcgttgtc cgaaatgtaa ctataataag
    25021 tcaagtgttg ttgatagtag acaggcagaa gatggcaata cgattcgtcg ccgcagagaa
    25081 tgcgaaagct gtcacacgcg ctttacaacc tttgagcgct tagaagagct tccattacta
    25141 gtgatcaaaa aggacgggac tagggagcag ttttcaagag ataaaatctt aaatggtgtt
    25201 gttcaaagtg cccaaaagcg tccggtgtca agtactgaca ttgaaaatct catttctcgc
    25261 attgagcaga aggttcgtac agcctatgaa aatgaggtgt caagtactgt tattggcaat
    25321 ctggtgatgg aggaattagc agagcttgat gagattacct atgttcgttt tgctagtgtc
    25381 tataaaagct ttaaggattt agacgaaatc gaagagctct tacagcagat tactaatcgc
    25441 gttagaggaa aaaagaagag cagtgtagat gatgaagcct attgatacct tttcttatat
    25501 taagcataat caggttcaat acgattcaag cagcctgatt cagttgtatt ttcctattat
    25561 tggaaatgac gcagtggcag tttatcagta tttggttcac ttttttgatg atggctcagg
    25621 agcccacaaa tttagtgata ttttaaacca tctgcagttt ggaatgaagc gcctagagga
    25681 agccttggtg atgctgacag ctattgattt gctggtctta tatcagctgc cagatgctta
    25741 tttgataaaa ctacatcagc ccttgggcag ggaagccttt ttaaataacc caatttatcg
    25801 taggctttta gagcaaaaga ttggagatgt agcggttttg gagttgcaaa tggtgattcc
    25861 gaaccaggct agaaacatct caaagacctt ttcagatgtt tttggaatag actctcagga
    25921 gcttaagcag cctcagccat caaagataaa ttttgattta gatagctttc agcagctaat
    25981 gcggcgtgac ggtcttaggt ttgaggatca tcaaaaggac gttatcagtc tttacagtat
    26041 ttctgagcaa taccacctaa cctggtttga cacctatcag ctggctaagg caacagcagt
    26101 cggcggcagc attcgcccag agcgcatgct agtcaagaag cagcaagagg gcgctcaaaa
    26161 aacaagtgaa tcgttctcac cagctgagca ggttgttctt agagagtcta agcaggacac
    26221 gcctcttgtc tttttagaga agatcaaaaa agctaggcga gctagagtca caaaggacga
    26281 aaaggaattg ttgctgactc tagcccgcat gaatttcttg gacgaggtca tcaatattat
    26341 ggtattatat accttcaata agaccaagtc agctaatctt cacaagactt atctgatgaa
    26401 aatggcaaat gattttgctt accagcgggt tttaacagcg gaaactgcta ttatcaagac
    26461 acgcgccttt ggtgagcgta agcagcaggc aaagtcacag cagtccaatg tgcctaagtg
    26521 gagcaatccg gattatcaag aaaaaacaag tcaggaagaa caggcaaagc tagagcagtt
    26581 taagcaggct gccttaaaaa ggctggagaa cctaggaaag agtggtgact agatggaaaa
    26641 gatcgggaaa atggtagagc atttgggaca ggctagtcgt gtagctagtg ctgagctgat
    26701 tgaggctata cttgctgatc aggaggtggc tgagtttatc aaggctcacc agctatctca
    26761 ggcagaaata aagctgagtt tatcaaagtt caaccagttt ttagttgagc gccggaaata
    26821 ccagacaggt gatgagacct atattgctaa gggctatcag cccattttgg tcatgaacga
    26881 gggctatgca gatgtgtctt acctagagac aagagagctt gttgaagccc aaaggcaggc
    26941 agctattgca gatcggattc atttggttag tctgccaaga tcttatcgta gggtttcttt
    27001 gtcagctgtt gatgttaaca atgccagtcg tatgcaggtg ttttcagagc ttttggattt
    27061 tgttgagcag tatccagcgg cagagcaaaa gggtctctac ctttatggcg atatgggggt
    27121 cgggaaatcc tatctgatgg ctgctatggc acatgaattg tctgaaaaaa agggtgtatc
    27181 aacaactctt cttcattttc ctagctttac gattgatgtt aaaaatgcca tttcaaatgg
    27241 ctctgtcaaa gaagagattg atgccatcaa gcatgtccct gttttaattt tagatgatat
    27301 tggtgcagag caggcgacct catgggtgcg tgatgaggtg ctacaggtta ttttgcagca
    27361 tcgtatgcta gaggatttgc caaccttttt cacctctaat tacagctttg cagatttgga
    27421 gagaaaatgg gcaaagatca aaggaaatga tgagacctgg caggccaagc gtgttatgga
    27481 gcgtgtgcgt tatttagcac gtgaatgcca tttagaaggg gttaatcgcc gccagggcta
    27541 gctaaacgct agctcaagcg atggataatg agataaagaa aaggagaatc atggttttac
    27601 ctacagttgc cattgttgga cgtcctaatg ttggaaagtc cacgttattt aaccgaattg
    27661 caggagagcg tatttctata gttgaagacg tcgaaggggt tactcgcgac cgcatttaca
    27721 cgactggtga gtggcttaac cgccaatttt cattgattga cacaggtggt attgatgacg
    27781 ttgatgctcc ctttatggag caaatcaagc atcaggctca tattgcgatg gacgaggcag
    27841 atgttattgt ctttgtggtt tctggtaaag agggcgttac tgatgcagac gaatatgtct
    27901 ctaagctctt gtatcgtacc aacaagccag tgattttggt tgtcaacaag gtggacaatc
    27961 cagagatgcg aaacgatatt tatgattttt attctcttgg cttaggagat tccttcccgg
    28021 tatcatcagt tcatggtatt ggtacgggtg atgttttaga tgctatcatt gataacctgc
    28081 cgatagaaga gccagtagaa aacgacgatg tgattcgctt tagcctaatt ggacgtccaa
    28141 atgttggaaa atcaagcctc attaatgcga tcctaggaga agagcgtgtc attgccagtc
    28201 ctgttgctgg tacgactcgt gatgcgattg atacaagctt taccgatgaa tccggtcaag
    28261 cctataccat gattgatacc gcaggaatgc gtaagtccgg caaggtctat gaaaatactg
    28321 aaaaatactc agtgatgcgt gccatgcgtg ccattgaccg atcagatatt gtgttaatgg
    28381 ttattaatgc cgaggagggc attcgtgact atgataagcg gattgcaggc tttgcgcatg
    28441 aggcaggtaa gggcatgatt atcgttgtta ataagtggga caccatcgaa aaggataatc
    28501 atacagtagc taggtgggag gctgatattc gtgatcaatt tcaatttttg acctacgccc
    28561 ctattatctt tgtttctgcc gttacaaagc agcgcttaaa caggcttcct gagttgatta
    28621 agcgtatcag tgatagtcaa agccagcgga tctcgtcagc tattttaaac gatgtgatta
    28681 tggatgctat tgcgatcaac ccaaccccaa cggataaggg acggcgtcta aagattttct
    28741 atgctacaca ggtttctgtg aagccgccaa cctttgttgt ttttgtgaat gaagaagagc
    28801 tgatgcactt ctcttatctg cgctttctag aaaaccagat tcgtgctgct ttcacctttg
    28861 aagggacacc aatcaagctg attgcgcgca atcgcaaata agccctttta ttactcttgt
    28921 tagtattgga agcagcgagt gctgttgatg tgcggtgtct agaccttgtg tgtcaggact
    28981 tttgaccgac caataagcct taccagaaat gagaggctgc tatccaaata gagcttacca
    29041 gcaagcaagg cgtgccaagc attgatgtca catgataatc attagcccta ggctagtgat
    29101 tttttagtgc tttaaagcct atcagaacag ctatatacag ctactcaaat atgttttaat
    29161 agcctttaag agagattttt gcaggaaatc taagctgaag tttgttataa tcaaaggata
    29221 agcaaaaagg tgggagcaga tatggctaga ttaattccgg ggcggattcg caatcaaggc
    29281 atcgagcttt atgagcaagg cttggtgaaa atcatagatg acaggactga ccttcttcga
    29341 gcagaggtgg atacttatca ggttcaatat ggtatcaatg atgaggatat taggtgtcag
    29401 tgtgattatt ttgagcgaaa gcagtattgc cagcacattg cggctctaga atattttctg
    29461 aaaaataatc agaagggcaa gtcgctctca gagcagctta acaaccagct ggaaagtaag
    29521 gaggaaacta aaaagctgac ctcctttggt agtctttttt tggacagttt gcacatgaac
    29581 gaggacgaca cgaccaaata taggctttta gcttctggtg ctaaaagtcc tttctcatct
    29641 gattactggt ggagccttaa gataaatcgc ttgcccggag agaaggctta tgttatccgc
    29701 gatatcaagg cctttattca tttggtcaaa gttgagggct tttaccagat tggaaagaat
    29761 tactttgagt ctctttccat attgcagttt gatcaggcta gtcaggagct gattcgtttt
    29821 ctttggcgtt tatcaacgca ttcagataag ttagattacg aatggctatt tcctaaccac
    29881 gctcgtcatc ttcggttacc ggcaggcttt tttgaggagg gcattgacct gctgacgggg
    29941 ctttacgagt tttcatttga gacctcctct caaacctatt ctcatcttta tgttcgacct
    30001 ctggaggcag aggctggtct ctttcagttt acagttgatg ttcatcgcag ctctattgag
    30061 ctttacatta aggaaaaaaa tatagagtat tttttcaata atgaatacct gctatacatg
    30121 aacacctttt accacctgag cctgaagcag caaaaaatgg ttcaagctat tcgcagcctg
    30181 cctattgagg ccgatttggc caagcacatt cattttgatc ttgatgatca ggctaagctg
    30241 gcagctagct tgctggaatt tcgagagctt ggtcaggtga aggctcctaa aagctttgat
    30301 attagagatt tccaagtgac ttttgtcttt gatattactg aaaaaggtga gttgacctct
    30361 cagctgattt ttgactatgg gagcattcag atcagtgata aggcaagctt agaccagctc
    30421 ccctttgcta gccattataa aaaagaaagc agtatttatc gtgccttgaa gcgctttggg
    30481 ctttctccgc agttttttgc taagaaagcc ttgactgacc ccaaggactg gtatcgcttt
    30541 tttacagaag ctgttcctta ttttgaaagt ctaggtaggg ttcagctttc ctctaagctc
    30601 caagatcagc gcttaatgga aagccctcag cttacagtca aacgtgaggg aggtctttta
    30661 gatatttcct ttgatttttc aacggtttgt cagactgata ttgaaaaggc tttggccact
    30721 ttgtttagtg atcgctctta ttttgtcaat cagtcaggca agctggtcgt ttttgatgaa
    30781 gagacacaaa aaatcagccg tagcttacag gaactaagag ctaagcagct ggcaaatggt
    30841 cacctccagc tagaaggaat agctgccacc cagctgtctc atctattttc ggatctgtct
    30901 tctgttcatt tttctgagga gctagagacc ctaatcaagg acctgcagca cccggatcgc
    30961 tttgagctgg gagagctggc cgttaaggcc aaggtgagag attatcagct gcagggcatc
    31021 aaatggctct ctgtgcttga taagtatggc tttggtggta tcttggcaga tgatatgggc
    31081 ttgggcaaga cactgcaaat cattgccttt ttatcaagca ggctaaccga gacctccaag
    31141 gtgcttatct tggcaccctc tagcttgatt tacaattggt tagatgagtt tagtaaattt
    31201 gcccctcaga tagatgctgc tgtatcctac gggctaaagc cggcacgaga tgctcttatt
    31261 caagaaggac atcaggtgac gattaccagc tattcttcct ttaggcaaga tttagaaacc
    31321 tatcaggcaa atgattatga ttatttaatc ttagatgagg cgcagatgat taaaaatgcc
    31381 cagaccaaga ttgctcagag cctgcgtgcc tttgacgtga agaattgctt tgctttatct
    31441 ggtacgccga ttgaaaataa gctgcttgaa atctggtcca tttttcaaat tgttctgcca
    31501 ggcctgctgc catctaaaaa agcctttttg aaaatggagg ccagagacgt ttctcgctat
    31561 attaagccct ttgtcatgcg acgcaaaaaa gaggaggtct tgccagagct accagaatta
    31621 atcgagatga attattacaa tgagatgtcc gatggtcaaa aagcgattta tctggcacag
    31681 ctaaggcaga tgcaggagcg gctgtctgct gcaactgatg atgatattaa tcgcagtaag
    31741 ctggaaatcc tgtctggtat cacacgtcta aggcaaatct gtgatactcc tagcctgttt
    31801 atggattatc aaggaggaag cggtaagcta gacaatctaa gaaccttgct gctgcaaatt
    31861 aaagaaaacg gtcatagggc tttgctgttt tcacaattta agggcatgct ggctcttgtc
    31921 aagcaggaaa tggatcagct tggcttatca tcttatacca taacaggctc aacaccggcc
    31981 aatgaccgtc aagaaatgac acgtgccttc aataatggct caaaggacgc ctttttgatt
    32041 tccttaaagg ccggtggtgt tggactcaat ttaacaggtg ctgatactgt tattttgatt
    32101 gatctatggt ggaacccagc tgtagaaatg caggccatta gtcgtgctca tcgtattggt
    32161 caggaggaca atgtagaggt ttaccggttg attacccgcg gaacaattga ggaaaaaata
    32221 ctggagcttc aggaaaataa gcgtcatctg attaccactg ttttagatgg caaacaaggc
    32281 ctagcaagca tgtctgtcga ggagatcaaa gaaatccttg gtcttcagcc ctagcatgta
    32341 tggcttttag cacacgctct taagcctatc agctaaaggc tagtgtctgt tctctataac
    32401 aaataaggca agagaataga ggtgatgagc tagtcacatc atttttgctt tgctgccttt
    32461 ctttttagga attactttga aaaataggat tatttagttt ataataggga atgctatagg
    32521 aaggagagtg agatagaatg acaaagcatg cgtttcctct ggttgcagat ggtgagccta
    32581 ttattgagtc agctaggcag atggctttat atgaaaacga agatttgatc acaaatattg
    32641 ctggcagcta tcaagataaa cattacgacg acatcataag agaccatcaa tttgctgaga
    32701 agactcctgt cgtctctaaa ggatcccttc atcattctcc agttgtcgat gaagatcata
    32761 gctacgctca aaaggccaga aggcaagcaa agcaggatgt caaagaaaaa agacaggctt
    32821 atattgctaa aaatatggct tatagcccaa agcaggcaag caagaaaggt caaagtgggg
    32881 ccttctcttc taaaaaacca gcgacagaat tgagccgttt tacagagaaa ttaaaccaag
    32941 agtcttatat tttagctgag cttcctcgtc aatataagga gccgcaaaat accagccaag
    33001 cagctgtcaa aaaaaataat tatgactttt tgaagcgcag ccaaatctac aatcatcaag
    33061 aagacagaga tcatcgtgaa aagaccattg ctcaagagct aaacctgagt cgctttgaag
    33121 atattaagta agctttatac agccttatgt ctgtcaacat taaaaggagt taacatgtca
    33181 aaaacctatc attttatcgg aattaaagga tctggaatga gtgccttagc cctgctgctc
    33241 catcaaatgg ggcataaggt tcaaggcagt gatgtggaga agtattattt cacacaaaga
    33301 ggcctagagc aagcaggcat taccattttg ccctttagcg aagataatat ttctccggat
    33361 atggagctga tagcaggtaa tgcttttcgt gaggacaaca atagcgaggt tgcttatgcg
    33421 atgcgtcatc agctgccctt taaacgctac catgagtttt taggtgagtt tatgaagcag
    33481 tttactagtc ttggtgtagc cggtgctcat gggaaaacct ctaccacagg cttgttgtca
    33541 catgtgctca agcacatgac ggctacttct tatttgattg gtgatggtac tgggcatggg
    33601 gctgccgatg ctcgttattt tgtgtttgaa tcagatgagt acgagcgtca ctttatgcct
    33661 tatcacccgg aatattctat tatcactaat attgattttg atcaccctga ttattttaca
    33721 ggccttgatg atgtgttcaa tgcctttaat gactatgcta agcaggtgaa aaaggctctt
    33781 tttgtttacg gtgaagatga ggaattaaga aagattagct ctcctgcacc gatttactat
    33841 tatggctttg aggacactga tgatttcgta gcctttgata tcacacgcac gacaaatggc
    33901 tcagacttta aggtaaagca caagggtcat gctattggtc agtttcatgt tccagcctat
    33961 gggcgtcaca atattttaaa tgctactgcg gtgattgcta atttatttat tgcaggcttt
    34021 gatatgaagc ttgttgcaga gcatctgaag agcttttcag gggtgaagcg tcgttttact
    34081 gaaaaggtga tcaatgacac tattattatt gatgactttg ctcatcaccc aacagaaatc
    34141 attgcaacgc ttgatgctgc taggcaaaaa taccctaata aggaaatcat cgctattttt
    34201 cagccacaca cctttacaag gaccattgct ttgctagatg actttgccca tgccctaaat
    34261 gaggctgaca gtgtttatct agcgcctatc tacggctcag cgcgtgaggt tgataagggt
    34321 gatgtcaagg tggaggatct agcggctagg gttgagcgcc cagccaaggt catctcagtt
    34381 gacaatgtat caccgctgct ggatcatgat aatgcagtct atgtttttat gggagcaggt
    34441 gatattcagt tgtatgaacg ctcgtttgaa gagctgctgg ctaacttaac taaaaataat
    34501 caatgattaa gcgacctgcc ttaggcaggt tttctcgtcg taaaggagga cctatgctaa
    34561 ttagacatgt gaatcagact gactgggaga ttattgctga tatcgaacag gccaattttt
    34621 ctccccaaga ggctgtagca gccaatgtga taaaagagcg tgcagagctt atttcggata
    34681 cctttcttgt ggctgttatc gccaatcagt ttgtcggcta tatcgaagga cctgtcattg
    34741 ctgagccaag gcttgaggat cacctatttc atggtgtgac caagaatcca gcaagaggtg
    34801 gctatatagc cattaccagt ctttctgttg ctcctggata ccaaaagcag gggattggca
    34861 cagctctctt agctgcaatg aaggatttag cagttgcaca ggatcggctg ggtatcatac
    34921 ttacctgtca tgactatttg attccttact atgagatgaa tggttttcaa gatcaaggcc
    34981 tgtcagcttc aaagcatggt ggctctgttt ggtatcaaat gctatggcag ccataggaag
    35041 gctattaaag cttagcatgt attaagaatt agtaacaaaa gggggatttt attgcattta
    35101 tagtgcaatt aggatataat ggcggttgat taagtttagg aggaatggct ttgactgatt
    35161 ttaaagatga tgagcaaaga cgtcagcagc aaaaaagctt caaagaaaag attctagccg
    35221 aattagaaaa agcaaatcag attagaaaag aaaaagaaga agagcttttt aaaaaggatc
    35281 tagaggttca agaggctgct agaagaacag ctcagcttta tgcagaatat aaaagacaag
    35341 aagcactaag caataacccc aaacaagcgt ctgatatagc agctgcgtcg caagagacga
    35401 cctcaacggc ttcaacagcc cacacctctg cgattaagct agaagagaca gcagtagcta
    35461 ctggggatca agcattgtcg ccaccagagg agcctgcatt gagtgaaagc ctgcttaagg
    35521 aagaggcaag tgtcgaaggt cagactaaga agggtggtcc agtgagaaga aaaacaagta
    35581 agcgccagca gacagatcga atggccaaaa aaatttcgac agtactgata tcgtcgattg
    35641 tcgctattat tgtggtgatt ggcctcgcag ggacagccta tgtgtatagt gcccttaacc
    35701 ctgttgacaa aaatagcgat gactttgttc aggttgaaat cccagccggc tcaggcaata
    35761 agcttattgg gcagatcctt gaaaaagagg ggctgatcaa aaatagtacc gtctttagct
    35821 tttacactaa gtttaaaaat ttcactaatt ttcaaagtgg ctactacaac ctacaaaaga
    35881 gcatgagcct agaagacatt gcccaggcct tacaagaggg tggcacagca gagcctacaa
    35941 agccagtact aggaaaaatt ttaattccag agggctatac cattaagcaa attgctaagg
    36001 ccatagaaac taatagtagg gcaaagaatc gtagcaaggc taaaacacca tttcactcaa
    36061 aggatttctt gaatttggtg acaagtgatg cctttattca agagatggct aaaaaatatc
    36121 cgaaattgct aggagatctt ccaagcaagg aagtagctac ttatcagcta gaaggctacc
    36181 ttttccctgc gacctataat tattataagg aaacaacact aaaagacctt gcagaggaaa
    36241 tgattgcagc ggcaaatgca aacctagcgc cttattatga ggcgattgca gctagtggca
    36301 agacagttaa tgaggtgctg actttggcct ccttagttga aaaggaaggc tctactgatg
    36361 acgatcggcg tcaaattgcc agcgtatttt acaatcgctt aaataatggc atggccttac
    36421 agtctaacat tgctatattg tatgcaatgg gtaaattggg agaaaagaca accttagcag
    36481 aggacgctgc tattgacaca accattaatt ctccttataa tgtttatatc aatactggct
    36541 taatgcctgg tccagttgat agtccagggc ttgcagctat tgaggcgact atcaatccag
    36601 cggcaacaga ttacgtttat tttgtagccg atgtgcgtac tggtgaggtt tattatgcaa
    36661 aaacatttga agagcactct gcaaatgttg aaaaatatgt taacagtcaa attcagtaag
    36721 gacaaacatg gtgctttagc atcatgtttg tgtttctgat tcgtcaaaag aaaaaggaaa
    36781 agagaaagat aatggcagaa aagacttatc caatgacagc agcagaaaaa gaacagcttg
    36841 aaaaggaatt agaagagcta aaattagttc gtcgtccaga ggttgttgag cgcataaaaa
    36901 tcgctcgttc gtatggagac ctttctgaaa actctgaata cgatgctgct aaagatgagc
    36961 aggcttttgt tgagggacaa atctcaacct tggagacaaa gattcgctat gctgagatta
    37021 ttgatagcga tgctgttgcc aaggacgagg tggcgattgg taagacagtt gttgtccagg
    37081 aggttggcac acaaacaaca gacacttatc atattgtcgg tgcggcagga gcagatattt
    37141 tttctggaaa gatttcaaac gagagtccaa ttgcacaggc cttgattggt aagaaaacag
    37201 gagataaggt taagattgag tctccagcag ctacctatga ggttactatc atcagcgttg
    37261 acaaaacaca ataagactta tctgactatc agtgcagtgt cctgatagtc tttttagtgg
    37321 cttgcttttt aatatcagtt gttgtggtct attaaaaaga gctgcacttt agaaagtttt
    37381 aactaagata ctttatgacc tagtctcata cattaaaaaa gcgaacaggt ctaattttcg
    37441 gaatccctga aaattagacc tgttcgtttg ttttatcttg agtcagactt ttgtcacaga
    37501 ctcttttagc tatcttagcg acgctttttt tgtttaccgg cgtttcggtt taacttagtc
    37561 ctcttgcttg tgctaagggc ttgcttttca gctgtaacgt ccttgcgtgg ctggtgagat
    37621 ttataggcct taggagggtt ctttgcgaac tcctctgcaa tttgcttgcg gagccttggt
    37681 tttaaaaggt aggttgtgat caattgctga atgatactaa agaaaccacc aactagccaa
    37741 tacaagccta atccggcagg caggtaaaac gacatgacaa tcatcataat tggcatggtg
    37801 tacagcatgg ctttcatttg ttcacgttgc tcctcaggga ctgccatcat tgacagccag
    37861 gattgaacga agtataaagc cgcaattaca gctgtaagca agacgctgcg atgccccagg
    37921 tcaatgccca taaaggtact tgttgagact cccttggtaa attggaccgc aacatacatg
    37981 gcagaaaaga aaggcatttg aatcagcagt ggcaaacagc ctataccgcc tagcgggttg
    38041 actccatttt cacgctgggc cgccattaat tctgtttggg ctgccatttt ttcttcagtg
    38101 cttgtagcgt ttttgatgcg ttgattaatt ggctcaaaaa aaggctttag gtaggccatt
    38161 ttttctgatt ggtagcttgc cttccatgat tggtagagcc caagtggtag gataatcgtt
    38221 ctaacaataa tagttacaac aatgatggca agaccatagc ctagggcggt gctgttagca
    38281 aagtaatcaa tgagaaagga aacgggcttt ccaaggtaat cccaaatgat gccctccggg
    38341 tgccccttgg cgtctctgcc gacacaccct gtcaatgtca gtaggaccga taaggcaagt
    38401 cctgagaaaa gtatgcgatt cgttttgagt ttcaatgtgt ttgtccttta atttttaata
    38461 tacctaacca ttttactgtt tttttgagaa attaacaata gttctacagt aggattttta
    38521 attgctgatc ctaaaatcat ggaaatcctc aaagtgagat ggattaacat caacataggt
    38581 cacctttgcc catttagaag gtccttttct gatttcctgg ataaagcgcg tcatctttgc
    38641 agggtcacta gcctgtgcta aaatctcaac agtcccatca ctattgttcc acacgcggcc
    38701 gtaaatatca ccaatttcca aagctagtgc gtaggttgaa tagcgaaagc caacaccctg
    38761 caccctgcct gaaacgatta gtctgacctt tttcataagt cacctctttt ctttttatta
    38821 tagcatagat agcttataaa tactaaaagt tgtcatggag caggcagcca aaggataggc
    38881 aaagactgca agtgggctat ctgctgaggt aaacaatagg tcttagtgca gcaaggctat
    38941 gtttatggtt agctctcctt cttgtcttct aaaaaggaaa gctaatgggc ttacgacacc
    39001 tgataagggg agaaagctcc ttttaggctg atagccttct gatggttttt atgcaaaaga
    39061 gtgaacaatt ttgtg
//
LOCUS       DARYLD010000014        39068 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYLD010000014 DARYLD010000000
VERSION     DARYLD010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39068
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(93..464)
                     /locus_tag="TU651_000608"
     CDS             complement(93..464)
                     /locus_tag="TU651_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896631.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TU651_000609"
     CDS             683..1321
                     /locus_tag="TU651_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL0896632.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TU651_000610"
     CDS             1517..2053
                     /locus_tag="TU651_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896633.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TU651_000611"
     CDS             2916..3320
                     /locus_tag="TU651_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL0896634.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TU651_000612"
     CDS             complement(3376..4860)
                     /locus_tag="TU651_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL0896635.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TU651_000613"
     CDS             5219..6442
                     /locus_tag="TU651_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0896636.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TU651_000614"
     CDS             complement(6532..6891)
                     /locus_tag="TU651_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL0896637.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7775
                     /locus_tag="TU651_000615"
     CDS             7056..7775
                     /locus_tag="TU651_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0896638.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEAGWVSC"
     gene            complement(7820..8647)
                     /locus_tag="TU651_000616"
     CDS             complement(7820..8647)
                     /locus_tag="TU651_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL0896639.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8908..9036
                     /locus_tag="TU651_000617"
     CDS             8908..9036
                     /locus_tag="TU651_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL0896640.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9090..10403
                     /gene="obgE"
                     /locus_tag="TU651_000618"
     CDS             9090..10403
                     /gene="obgE"
                     /locus_tag="TU651_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL0896641.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10524..10682
                     /locus_tag="TU651_000619"
     CDS             10524..10682
                     /locus_tag="TU651_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896642.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10735..11439)
                     /locus_tag="TU651_000620"
     CDS             complement(10735..11439)
                     /locus_tag="TU651_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL0896643.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11774..13174
                     /locus_tag="TU651_000621"
     CDS             11774..13174
                     /locus_tag="TU651_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0896644.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13184..14278
                     /locus_tag="TU651_000622"
     CDS             13184..14278
                     /locus_tag="TU651_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL0896645.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPRVVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14384..16378
                     /locus_tag="TU651_000623"
     CDS             14384..16378
                     /locus_tag="TU651_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0896646.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16392..16709
                     /locus_tag="TU651_000624"
     CDS             16392..16709
                     /locus_tag="TU651_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0896647.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16706..17041
                     /locus_tag="TU651_000625"
     CDS             16706..17041
                     /locus_tag="TU651_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0896648.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17041..17475
                     /locus_tag="TU651_000626"
     CDS             17041..17475
                     /locus_tag="TU651_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL0896649.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17550..18929
                     /locus_tag="TU651_000627"
     CDS             17550..18929
                     /locus_tag="TU651_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0896650.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18926..19078
                     /locus_tag="TU651_000628"
     CDS             18926..19078
                     /locus_tag="TU651_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896651.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19235..19975)
                     /locus_tag="TU651_000629"
     CDS             complement(19235..19975)
                     /locus_tag="TU651_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0896652.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(19975..22140)
                     /locus_tag="TU651_000630"
     CDS             complement(19975..22140)
                     /locus_tag="TU651_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0896653.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22332..24323
                     /gene="uvrB"
                     /locus_tag="TU651_000631"
     CDS             22332..24323
                     /gene="uvrB"
                     /locus_tag="TU651_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL0896654.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24662..24805
                     /locus_tag="TU651_000632"
     CDS             24662..24805
                     /locus_tag="TU651_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL0896655.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24817..26355
                     /gene="dltA"
                     /locus_tag="TU651_000633"
     CDS             24817..26355
                     /gene="dltA"
                     /locus_tag="TU651_000633"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL0896656.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26352..27599
                     /gene="dltB"
                     /locus_tag="TU651_000634"
     CDS             26352..27599
                     /gene="dltB"
                     /locus_tag="TU651_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL0896657.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27617..27856
                     /gene="dltC"
                     /locus_tag="TU651_000635"
     CDS             27617..27856
                     /gene="dltC"
                     /locus_tag="TU651_000635"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL0896658.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27849..29102
                     /gene="dltD"
                     /locus_tag="TU651_000636"
     CDS             27849..29102
                     /gene="dltD"
                     /locus_tag="TU651_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL0896659.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29136..30110
                     /locus_tag="TU651_000637"
     CDS             29136..30110
                     /locus_tag="TU651_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0896660.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30651..31910
                     /locus_tag="TU651_000638"
     CDS             30651..31910
                     /locus_tag="TU651_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0896661.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     GKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32083..33783
                     /locus_tag="TU651_000639"
     CDS             32083..33783
                     /locus_tag="TU651_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL0896662.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33812..35944
                     /locus_tag="TU651_000640"
     CDS             33812..35944
                     /locus_tag="TU651_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL0896663.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSTAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLVFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36020..37324
                     /locus_tag="TU651_000641"
     CDS             36020..37324
                     /locus_tag="TU651_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0896664.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37325..38185
                     /locus_tag="TU651_000642"
     CDS             37325..38185
                     /locus_tag="TU651_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL0896665.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38210..39040
                     /locus_tag="TU651_000643"
     CDS             38210..39040
                     /locus_tag="TU651_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL0896666.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10865 a         7375 c         9045 g        11783 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggctggc tgggttagct gctgaattga tagtaaaaaa gaccagtctt
     7801 agactgatct gtagggtgat tagatcgccc attctcctcc tcggaagatt ggaatgactt
     7861 ctccgtcttt ggtaatgcca tcgatatcca tttgttcaga accaatcata aagtccgcgt
     7921 gggctgttga gcgatttagg ccagccgctt cccaaatgtg ctgctcaggc attccaagtc
     7981 ttaggtcagt tcctggtgcc ctgtagtgaa ggctgtcaaa ctgataatca ttgaggagcc
     8041 ttgccttttt ttctaaacgt tcctgatgtt ggtcccaggc cttgacagga tctgtctcgt
     8101 aaatgcgatt cattttgaaa atggcatccc acaaagcgtc cacctgctct tcttcgcttg
     8161 tcaggtttgg aaaaaccata gcagcccatt cgggaccggc tgcagctgct agattccagc
     8221 tgactttgtt ggcctgagtg gcagcccgct gtttttcaag agcaatagct gttgcgcgtg
     8281 ttgctccagc tagcctatca gaatcaatat cagcaaagac gtttggattg gcagagcgaa
     8341 tgactaagcg gcttgctttt tgatcaagga gataatgtga ctgttcaacg acataatctg
     8401 gtacctgcaa gagacggtct tcatcagcct taagaagctt ctcgcgtgtg atctgatcgt
     8461 cattatagtc aacaagaacc tcagctgcac cagcctcata ggcttttttg gttaatagcc
     8521 gcgcaagctt gtgttgctct actgcaatag aaatgagtag tgtgtgacct ttttgaatgt
     8581 tgactccttt tttgataaga aggttagcgt atttttcaag ataatcgtca aaatgtggca
     8641 aaaccatagc agtctcctaa tatgttaatg ttgcaaaatt taatgtatca tatttgcgac
     8701 tatttcacaa ggagctagcc tgtttcatag gctaaatgtc tcctagaatg cctatcgtaa
     8761 aaggctcagt gttggttttc tctgatgagt taaaaaacga tccctttttt gatcagtttg
     8821 cgctgccctt gctaatagat atttgcttaa tagcgacatt cgtgttaaga tataagagga
     8881 aaaaatcaat agatgaggta tttaacagtg gcatttggag aaaatggacc tcgcaaaaaa
     8941 actgcctttg aaaagttgac aacagttgtt gtgatcgtga tggttcttgt gactgtcggt
     9001 ggacttattg cgggtgccct gtcagtattg atgtaagaaa acgctgaaag gcgttttttt
     9061 aggataagag aaggtttgag aagaaaagta tgagtatgtt tttagatact gctaaggtca
     9121 gtgttcaggc tggtcgtggc ggtgatggta tggtggcctt tcgtcgtgaa aaatatgtgc
     9181 ctaatggcgg cccttggggc ggtgatggtg gcaagggtgg ctctgtcatt ttcaaggttg
     9241 atgaaggttt gcgtacccta atagactttc gctacaatcg taagttcaag gccaaatccg
     9301 gtgaaaaagg catgactaag ggcatgcatg gtcgtggctc agaggatttg attatctcag
     9361 tgccacaggg aacgactgtg cgtgatgctg aaaccggtaa ggttctgacg gatctggttg
     9421 agcatggtca agaatttgtc gtggctaagg gtggtcgtgg cggtcgtggg aacattcgtt
     9481 ttgcaacgcc gcgcaatcca gcacctgaga ttgctgaaaa tggtgaacca ggagaggagc
     9541 gccaattaga gctagagctt aagattttgg cagatgtggg actggttggt tttccgtcag
     9601 ttggtaaatc aacgctacta agcgtggtct catcagccaa gcccaagatt ggtgcttatc
     9661 actttaccac tattgtgcct aatctaggta tggttcgaac caaatctggt gagagctttg
     9721 ctatggcaga tcttccaggc ttaatcaagg gagctagcca gggtgtgggg cttggcactc
     9781 agtttttgcg ccatattgag cgtacacgtg tgattctaca tgttattgat atgtcagcag
     9841 ctgaaggacg agacccttat gaggactatg tggcgattaa taaggagtta gaagcatata
     9901 atcttcgtct tatggagcgt ccgcaaatta tcgtcgccaa taaaatggat atgccagagg
     9961 caaaggagca gttgcagcgc ttcaaggaac agttagctgc tcagtatgat gactttgaag
    10021 aactgccaat aattttcccg atttctagct tggcacatca aggcttggat agcctattag
    10081 aagcaacagc agagctatta gcaaaaactg atgatttctt gttgtatgat gaggctgatt
    10141 tggctgagga cgaggcttat tatggctttg cggctgagga aaaggccttt gagattagtc
    10201 gtgctgatga tgcagcttgg gtattgtctg gtgagaaatt agagcgtctc tttgtgatga
    10261 ccaatctgga gcgcgacgaa tctatcatga aatttgctcg tcagctacgt ggcatgggtg
    10321 ttgatgaagc gcttcgtgag cgtggtgcta aggacggcga cattgttcgc attggcaagt
    10381 ttgagtttga atttgtagac taatgacaaa taccaagctt agctgttttt tgtagcaagt
    10441 gatgctgagt catatctgaa gtaggctgtt tgctcaattc acagcaatga ggtcttggtt
    10501 gatgtgagct agggaggttt tttatgggag ataaaccaat atccttcaag gataaggacg
    10561 gtaactttgt ttcggcagca gatgtctgga atgctgaaaa attagaagaa ttatttaatc
    10621 tcttaaatcc caataggcgt ttgcgtttgg aacgtgacaa attaaaaaag gatgaagctt
    10681 aagtgcactt cctctcaatc gttagattta gtgtctaact tttgagggtg cacttcaagg
    10741 cttcgtcctt ttttgatgct ttttttcttg gtgatgctgc aaatgtagcc aattaaaaaa
    10801 ggtgtaaatg tcattaacaa gaaaggctgc aaaacaaatg accactgcgt attggctggt
    10861 atttgcttga gcagcataga gccacaggag aattaagacc aaatcattaa gagcataggc
    10921 caaggcaaaa taagggctac gtttgtagct taagtaggct gctgaaaaag aggtggcaat
    10981 agataaggta gaaacaggca gataggctgt cttaagatag gctaagatag catagaacaa
    11041 gctggtaact agtatggtaa gaaccactaa gcgcagccgg tctgctgttg tcaagcgtga
    11101 gatggttacc tgagatgtct ggtcttcaaa tgggtggctt agccaggtaa acagtgacaa
    11161 aatagccatc ggcagggtca tgaagagata ggttatcagc tccccgtaat aactgtttaa
    11221 tagtgacaga taggcataaa taagggagaa aataatggcc aagctctgtc caatcggatt
    11281 tgccttggca ctaaagatta aagctgtcac accgattaag gaagctatca gtgctaaggg
    11341 agcttgttct ccaaagaaaa aggcactgag gagaatagcc gaaatggagg ttaaccaaag
    11401 cgtccactcg gtttttgtaa aatagtttaa ataagccata tccttattca agcataggcc
    11461 tttttatctg tcaatagggt gtcgacctta gggaaaaata agctaatacc tgccatagtg
    11521 caattggttg tgaggcacta atactagcag ataatggtgt taactagagg caaatgagct
    11581 aagagtttcc ttattggctg ctgctaatac tccttgttga ctggtttaga agaaaaggac
    11641 taagagcctt agcttggctt tgtcagttag tttccttgat gataaggaaa aactagattt
    11701 tttaaagcgt ttacagtgtc cttttttctt cctataatag gggtataagt gacaaaaaga
    11761 aaggaaaaag catatgaagc aatcaaaacg ccgttaccaa tttccagaag gttttttgtg
    11821 gggaagctca acatctggcc ctcaaagtga ggggactgtt tctggagatg ggaagggacc
    11881 tagcaattgg gactactggt ttagtctgga gccagataag tttcatcatc agattggtcc
    11941 agaggtaacc tcaacctttt acaccaacta caaaagcgat attgctcttt taaaagagac
    12001 cggtcacaca gcttttcgga cctctattca atggtctcga ctgattccag aaggggttgg
    12061 tcaggttaat ccaaaagctg tagcctttta ccgagaggta tttcaggaaa tcatggctca
    12121 ggacattaag ctgattgtta acctctatca ttttgatctg ccttatgcct tgcaaggaaa
    12181 gagaggctgg gaggctaagg agacggtctg ggcttatgag acctatgcta agacctgttt
    12241 tgagcttttt ggtgatttgg tggatacatg gattaccttt aacgaaccta ttgttccagt
    12301 cgaatgcggt tatttggggc attaccacta tccttgcaag gtagatgcca aggcagctgt
    12361 tcaagtggct taccataccc agttggctag ctcacttgct atcaaggcct gccacgagtt
    12421 gtatcctaag cataggatta gtattgtgct taatgtgact cctgcctatc ctagaagtga
    12481 tcagccagaa gatgtcaagg cagcgagaat cgcagagctt ttccagacta aatccttcct
    12541 agatccgtct gtcttaggag tgtacccaga agagttagta gttcttttag aggcagctga
    12601 tttattgccc cagtatagtg ctgatgaatt ggctattatc aaaaacaatc ctgttgattt
    12661 cttgggagtt aattactatc aacctttgcg tgtgcaagcg cctagcaaaa caagacaaga
    12721 tggtgaacca atcacgctag cctcttattt tgaaccttat gatatgccag gcaaaaaggt
    12781 taaccctcat cgcggttggg aaatctatga gcagggcctt tacgacattg ctcttaattt
    12841 aaaagagcat tatggcaata ttgactggtt agtaactgaa aatggtatgg gagtagaagg
    12901 tgaagaagcc tttttagttg atggtcagat ccaagacgat taccggattg cctttatcga
    12961 agaccatttg attcaattgc acagggcttt agaagaaggc gcgaactgta aaggctacct
    13021 cctgtggacc tttattgatt gctggtcttg gttaaatgcc tataaaaatc gttatggctt
    13081 ggtagccttg gatttagaga ctcaaaaacg aacccttaaa aaatctggcc actggtttaa
    13141 gaccctgagt cagacaaatg gttttgataa ataggagcgt atgatggtca ccttaggatt
    13201 ttccctttac cctgagcggc atggttttgc taagagtaag gcttatattg atttactgca
    13261 ctgctatgga gccaagcgct tgtttatgag cctcttacag ttggcgccaa atgatcccaa
    13321 gacctttaag ttttatgcgg atctgattgc ttatgccaat tgcttgggca ttcgggtcat
    13381 tgcagacgtt agccctgctt ttatcaagca ggctggttgg tcagatcagg ttattgaaga
    13441 ggctcatgct tttggcttag caggcttgcg tttagatgag gccttgcctt tagaggatat
    13501 tgttaggcta acgaaaaact cttttgggct taagattgaa ctcaatatga gtactgacaa
    13561 gagtttattg acagccttgc taaaggcagc tcctgatcgg agtaacctca ttggttgtca
    13621 taatttttac ccgcacgcct ttaccggcct gtcactggag cattttaagg aaatgtccca
    13681 tttttaccac gagcatggga ttgcaacggc tgcttttatc acagcccaat cagcaaagga
    13741 aggcccttgg ccgctgtcag agggcttacc gactgttgag gctcatcggc aattgccaat
    13801 tgacgtgcag gtggaactga tgaaggcgac aggaactatt gatactgtca ttttgtccaa
    13861 tcaattcatc actgaagatg aactcgttca gtgccgtcaa gccttggata gatcagtcat
    13921 gtctattaag gtcaagcctc tggttgattt gacggacata gaggagaaga ttatctgtta
    13981 cccacattgt tatcggggag atgtatcaga ttatgtgatt cgctcaacca tgccgcgtgt
    14041 ggtatatgct caagaagcaa ttgctccaag agagcagccc aagcaggtta agcgaggcag
    14101 tattatcatt gataatgacc gttacaacag gtacaaggga gaattgcaaa ttgcactcaa
    14161 agcctttacc cttagctcaa aggccaatgt ggtcgccaac attaaagagg attacctaag
    14221 cctattagac gagttgaagc cctggcagga gttttcattg gtgattgaga ctgactagtc
    14281 tggcttcaca atcgatacgg aaaatgatgg tcactttttt caggaaacat ttgctaaact
    14341 aagagagtaa agaaagcgtt ttctaaaaga cgaaggagga atgatgctat caaaaaaaga
    14401 aatggctata gtagcatttc taatcagcca aaaagggcag tttgtctcta gtgctacctt
    14461 ggctaaggct attggcatga gtgatcgcac agtcagaaaa tacctaaagg agctgattag
    14521 cagccttcct agtaagggag cgcacatcat ttccaagcaa ggtcagggct actgtttaga
    14581 gattgatcat tctatggcgt ttgagatctt ttggcaggaa agcttggcct ctaaaaagcg
    14641 cttggctgat gtgactcagg tggaagaaac agttgatcgg gagcattatt tgctaaataa
    14701 attcttcttt gaagagcccg tttgggattt tgaagagctc tgccaagaat tgtatattag
    14761 tcggacgacc ctaaaccatg ttttagcggt tattagagac cgtattaggc cttatcagct
    14821 acagcttgat gtgagtcatc agcgcgttca ggtgacaggt aaggaagagg ctattaggca
    14881 ttttatcatg gattattttt ttgctaccag ctttgatgac tccatgtacg ccatagtaga
    14941 caataccttt cttgatcata tcaagtttgc tgatatcaca ataattgttt tagatgaatg
    15001 tcgagatgcc aaactaaagc tttctgattt tgtcatgcac aatttggttt tgcacattgc
    15061 cctaatggtt cagcgtattc ggtctggcta tccgttagca tttttttcca ttccagcagc
    15121 tattcgccaa tcagacgagt atcaagtggc tctacgtatt ttatatcgag tagaagaagt
    15181 gatgggcatt cgttttccta aagaagaagc taactatatt gctttacacc tcaaggttaa
    15241 gcattccgtt gatggcagcc cacaggacaa taaggccgat gacttgctga gaagtcattt
    15301 aaaagcaggt attgtcaagg ctagtcagct gacaggtatg tctttggagg ctgatagcag
    15361 cttgcttcaa ggcctattgg cccatatgaa gcctttagcc acaaggcttg aaaatcatat
    15421 tcagctgacc aatcccttaa ctgaggagat taaaagcaaa tacccagagg cttttgccct
    15481 gaccaagcaa gcttttgaga atattcctga gcttcaggct tatgacctgt ctgatgacga
    15541 atgggcttac attagcttgc atatcatggc agctattgag cgctattcca atcgtcacaa
    15601 actgagggtg cttgtggttt gtgccacagg ctatggcagt gccatgatgc tgaaaaatcg
    15661 cttggaaaag gaatttgaag gtcgctttca gattgtagat gttatcagct actatgaaat
    15721 aacacaggaa cgactgcaaa cggttgatgt gattatttct tctatcagcc ttgctaatgt
    15781 catgttttta acgccagtca ttactgtcag tgtcttttta tctgatcaag acatcaaagc
    15841 cattcgccaa tttatcgggg agcaggaggg aataagaaga gaagctgcgt cgtcatcgca
    15901 gatgagcttg gaaaaagcag agcagattct aaaaggtgtc tttagtccta agcgttttct
    15961 ttatgtgaaa gaaaaactat caaagaaggc cttgctgtta aagatgattg cttgtcttga
    16021 cgaagcaatg gatgaagcct ttgttgaggc cttttatcac caaatcgtgt tgagggaaaa
    16081 ttatagctca attgtttttg gtgaggtgct tgcctttcca cacccggcta atcccatgac
    16141 ctattctgaa caggtggtgg tggctgtctg tcaagagcct attgactggg acgagagtca
    16201 tcgggctgtt cactttatct ttttgttgtc accgtccaag ggacgtaaca gctatttaaa
    16261 atatatctca ccgagcttgg tgtcttttgt caatcaagca gagcttcagc aggctttatt
    16321 agaagaacca agctatgcac aattcatcac attatttacc ccactcatca ctgaataaaa
    16381 ggagaagtat tatgaaaacc attatgttag tttgtaatgc cggcatgtca accagtatgc
    16441 tggtgactaa aatgcaaaaa gccgctcaag cgcgtggcat cgaggttgag atttgggcag
    16501 ttcctgtgag cgaagctgac aatgaggttg ctgctaaaac cattgatgtc ctcatgttag
    16561 ggccgcaggt caaattctta ctaaaggact ttaagaccaa atttgaaccg gcaattaagg
    16621 tagatgtcat taacatggct gactatggcc tcatgaatgg tgacaaggtg cttgaaacag
    16681 ccctaacaat gatggaggaa gaggtatgac acaatcatca aacctagagg ccattatggg
    16741 attaatcatg tatggcggtg aggccaaggg caaggctgta gaagctattc atgcagctag
    16801 agatggtcaa tttgaaaagg ctcagcactt gcttcaagag gctacacatt ctttaaatgt
    16861 tgcccataga tcacaaacca atttgctatc tcaggaagca gctggagatc aggttgattt
    16921 gtctttattg ctggtgcatg gtcaggatca tatgatgaca gccttagcct ttattgattt
    16981 ggccaaggaa ttggtcgctg tttatgacaa aatatcaaga atccaaagag gtgagctatg
    17041 atgatgatta cagcagaagg agatgtctct gtcactcaat gcttcaaggc tatactaagc
    17101 tctctccaag aggattatca tgaaaacacc ctgagacggc tgccaccagc tgaattaaaa
    17161 gcagggctaa gctacataaa gcattatggc aaaagcaagg agcataacgt tagagtgctg
    17221 atcacagcct tagaagctcc gcacttatat gctgcttgct ttagctctaa tcatgggcta
    17281 aaaacattaa gctaccgctt agaagctctg ggagagaagc gtaccaaaat aacctattgc
    17341 tacgactatc agccacttga tgtctttcaa aaagccaatc agctgatcat tgggaagctt
    17401 tttaagaaga gcttcaaacg gcaatcacaa gcccaattgg cagcccttat ccaatatgct
    17461 aagcagctaa gctaggggaa gatttgagta cagattatct ggctgattat agggcttatc
    17521 atactaaaaa atagaaacag gagaaaatta tgtcacattt ttcggataag tttatggaga
    17581 tttcaggaaa gatgggatcc cagcggcatt tggttgccat tcgtgattcc tttatttcgc
    17641 taatgcccat cacgatggcg ggctctgttg ccgtcttgct gaatgttttc ttgcgtgata
    17701 ttccaaacaa tatgggctgg actggttttg cagcagccat gcagcccatt attgacatca
    17761 atggttatgt gtattttggg acaattggta tcatggcact cttttttgcc tttgcttttg
    17821 ggtatcattt agctcttatg cacaaggtga atcctttggc tggaggttta atctcctttg
    17881 cttcctttgt cgccaccctt cctcaaagct taaccatttc cacaccactt gaaggggcgt
    17941 cagcaagttt attagcaggc ttaaaggata tgggactatc agtggtcact gcaaatggag
    18001 cccgagtttt agaaacaagc cagtggggag caattgccct caaatatgct ggagcaacag
    18061 gtctttttac agcattgatc attggctttt tatctagctt tgtttatgcg actttgacca
    18121 aacgtaacct gaccatcaaa ttgccagata atgtgccacc tgcggttaat aaggcttttg
    18181 cggctattat tccagggaca gtcgcgattt atgtgtcagc gatcgtagct taccttattt
    18241 ttgccctcac aggctcgtct ctaagtgata tgatttcgac ctatatccaa ttgcctttgt
    18301 tggggctgtc tcaagggctt ggctctgtta tcctgttaac cttcttggtt caattgctct
    18361 ggttctttgg tttgcatggt cacaatgtct tagcacccgt gcttgatggt gtgtacttag
    18421 tggctctaac agaaaataca gctgcctata ataccagtca gagcgttgct aatctgcctt
    18481 atctctggac gagaggctcc tttgatgcct atgcacaaat gggtggttca ggtgttactc
    18541 tggctctgat tattgctatc tttattttct caaaacgtga ggagcacaag accattgcca
    18601 aattatcagc accgatgggc gtgtttaaca tcaatgagcc aattaccttt ggtatgccta
    18661 ttgtcttgaa cccaaccttt gctatcccat ggctaatcgt accaccaatt tgtgctagca
    18721 ttgcttatgc tgccacagca ataggcttga tccctcccgt tttcttgcca gttccttgga
    18781 ttacgccagt tggactttac gcttacttgg ctactggagg tagtgttatg gcaggtctgg
    18841 tttccttgtt taacctcttt gttgcctttc ttatctgggc accatttgtc atgtcagcta
    18901 ataaagaaaa agcgagtgac ctttcatgac agcaaaaaac ggagcaagct ttttaatggc
    18961 tataggattt ttccttattg ccattagtcc aatggttggc aacaaatacc tacatatcgt
    19021 gacaggacta gcttttgttg gcttagggta ttatctcact aagcgcaagc gtccttagtc
    19081 aatgcgagca gctagcccct atgaaaagac aaacctaagg gctagccttg attttctatc
    19141 ttggttatcg catttaaaag caagcaaaaa agcaagggta gatgcttacc tttgcttttt
    19201 ttattttttg acctttaata gaatatcttg ctacttaaac atttaagacc ttatctaaaa
    19261 attcaattaa gcgtgggtgc ttagggtgat caaagatttc ctctggagta ccgtcctcta
    19321 ggaattggcc gccgtctgta aagatcacac gattagccac ttgacgagca aagcccattt
    19381 catgtgtcac aatcagcatg gtcatgccct gctctgctag gtctttcata acgtttaaga
    19441 cgtctccaac catctcaggg tcaagagcag aggtaggctc atcaaagagc atgatatcag
    19501 ggttcatggc aagacttctt gcaattgcaa cacgctgctt ttgaccacct gatagacttc
    19561 ctgggaaagc gtcagcctta tcagctagac cgaccttctc tagaagagca agtccctttt
    19621 ccttagccgc ctcctttgag acctttccaa gctcaactgg tgcaaaggta atgttatcaa
    19681 ggactgtcat atgtggaaag agattgaagt gctgaaacac catgccgata ttttcacgag
    19741 ccttatcaat attggtatta ggatctgaaa gttcaaagcc atcaaccaca accttaccac
    19801 tagtaatgga ttcaaggaga ttgagggtgc gcaggaaggt tgattttcca gagccagatg
    19861 gcccgataat acaaacgaca tcaccctcgt aaaatttagc attaatgcct tttaagacct
    19921 cattttgccc ataggatttg tgtaaatctt gaacatcaat ttttaattct gccattagtt
    19981 aagcctcttt tctaaacgtt ttgcaagcct tgttaagagt gtaatcataa tcaagtagat
    20041 aactgctagg atagcataca tgcggaagga ttgatagttt ctagcgataa tgattttccc
    20101 tgtttggaag agctccacta aaccgatcgc tgagactatg gtcgtatcct tcaaggaaat
    20161 gacaaactga ttgatgaagt ttggcagcat tagcttaatg gcctgaggaa ggataatcct
    20221 tcgcattgtt gtgtgatatg acaagcccaa gctgcgacta gcctccattt gacctgccgg
    20281 cacagcctcg atacccccac gaacaatttc ggcaatatag gctccaccat ttagcgaaag
    20341 tgcaatagta gcagctacaa aatcgttaat cggtgattga tgcccagtca tgctttcaat
    20401 gaggtttggc actccccaga agataaaggc agcaacaatc atcaagggga taccacgcac
    20461 cacatcaaca aagatagtag aagccatgcg caggttcttt gatggggata cagccatcat
    20521 tccaaaaaca ataccaataa ccaaagcaat ggcaaaggag atgagtgtca gaccaagggt
    20581 tgttccaagc ccagccaata attgcttgta gttattagct aaaagtccat aaatagttga
    20641 ctcatcggct gttttgacag atgcctctga atcaaggtat ctgctgatga tggcgtcgta
    20701 ttttcctgat gctttaagag cagccaaacc gttgttaaac atttcgatga gctcagggtt
    20761 ggctcctttt ttaacagcaa aaccatactc accagaaggc tctcccttga taggaatatc
    20821 aagcttgtgg cctcgctgaa tagcgtacct taaaatagct tcatcatcca taagcccgtc
    20881 aatagaacca gaatttaagc tatcgtacat tgaggaggcc tcatcaaagg cttttagacg
    20941 gtaaccataa atatccttgt tgctttcaag gaaatcatag gaggctgttc cttttttggc
    21001 accgactatt ttacccttga ggtccttgta tgatttgata gagcttccgg atttgacccc
    21061 aaggcgaatg tttgatgtgt agtaggaatc tgaaaaatca aaaatctcac gacgtgcagg
    21121 tgtgatagac atacctgcaa taacagcgtc agcctgacca gcttgaacag catttaaagc
    21181 agcgtcaaag ccaggattgc tgatctcaat ggtaaagcct tgctgcttag caattgcctt
    21241 gatgaggtcc atatcaatac cgacatattc tccgctgcca atttgaaatt caaagggagc
    21301 aaaggaggag tcagccacga ttttataaac cggctttaaa ggagtggcct tagcagaggc
    21361 atcgccagta gccttgcctg ctgtgacctt gtcattgctg ccaagccatt ttgtcatgat
    21421 agcttgatag gttccatcag ccttcatagc gcctaaggct tcattgaagt cgtcaatgag
    21481 ataatcatag ccgctgcctt ttttgacagc aaagccaaag cttccaatag cctctccctt
    21541 catgttgatc gcaagatcct gcttttggtt aatggcatat tgaatgacag gctcgtcgtc
    21601 cataacagcg tcaatagagc ctgttgcaag actgttgtac atcaggtcac ctgtgtcaaa
    21661 tgttttaaca gtataaccat acgatttttt gtatttatct aagaaggctt gagcagctgt
    21721 tccattttta acaccgactg tttttccttt tagctcgcta tatttcttaa tagggttagc
    21781 ctttcttgta gcaataacaa tttttgtatc gtaataggga tctgaaaaat ggaagacctt
    21841 ttgacgagca gcagtgatgg tggtgcctgc cataagggcg tcagcttgac cagactgaat
    21901 ggcattgaca gcagcatcaa agccagggaa tgtcatattg atattccaac cctttcgctt
    21961 tgctacttca ttgatgatgt caacatcaat ccccttatac acctgatctg aatccttgaa
    22021 ttcaaacggt gcataagcag tatcagaaac aatatcaatt gtctctgcac ttgcaatccc
    22081 agcagtcatc aaaacaactg acagcattgc aagcatccat gcttttaatg tgtttttcat
    22141 actagtctcc ttaataaaaa taaaaaatat gcctaattat agcagatttt tttcaaacaa
    22201 gcaaatcatc tcttcttttt atgtcataaa acctaacata aacaactaaa atagtcaaaa
    22261 agctttgata gagtctttaa gtccttaact atgttacaat agataagaga taagatattg
    22321 aggaccaata aatgattgat aaacgtgatt ttaaagcatt taagctcgtg tcaaaatatg
    22381 ccccctcagg agatcagccg caggcgattg agaccttggt tgataacatt gaaggtggtg
    22441 aaaaagcgca gattttacta ggagcaacag gaacagggaa aacctatacc atgagtcagg
    22501 tgatcagcaa ggtcaacaag ccaacgttag tggttgctca taacaaaacc ttggccggtc
    22561 aattgtacgg tgagtttaaa gagttctttc ctgaaaatgc tgtcgagtac tttgtatcct
    22621 actatgacta ttatcagcct gaggcctatg ttccttctag tgatacctat attgaaaaag
    22681 acagctctgt taatgatgag attgacaagc tgcgccattc ggccacctca tcgcttttag
    22741 agcgtaatga tgtgattgtt gtggcttcgg tttcttgtat ttacggattg ggctcaccaa
    22801 aggaatatgc tgattcagct gttagcctgc gtcctgggca ggagatatcc agggatcagt
    22861 tgctcaatgc ccttgtagac attcagtttg aacgcaatga cattgatttt caacgtggac
    22921 gctttcgtgt gcgtggtgat gtggttgaag tatttccagc ctcaagagat gagcatgcct
    22981 ttcggattga gtttttcggt gatgagattg atcggattcg tgaaattgaa agcctaacgg
    23041 gtaaagtatt aggtgatgct gatcatttag tgctttttcc ggccactcac tttgtgacca
    23101 atgatgagca catggagcag tctattagca agattcaggc agaattagca gaccagctta
    23161 agctatttga agcagaaggc aaattgctag aggctcagcg cctgcgtcaa aggacagaat
    23221 acgatattga aatgctacgt gaaatgggct acaccaatgg ggttgaaaat tactcacgtc
    23281 acatggacgg gcgttcggca ggagagcctc cttataccct gttagatttc tttccggatg
    23341 attttcttat catgattgac gagagtcaca tgaccatggg acaaattaaa ggcatgtaca
    23401 atggagacaa ggctagaaag caaatgcttg tggattatgg ctttcgtctt ccgtctgcct
    23461 tagacaatcg tccgcttcgt cgggaggagt ttgaaagtca tgtgcaccag attgtctatg
    23521 tctcagcaac gcctggagat tacgagatgg agcagactga tacgattgtg gagcagatta
    23581 tcagaccgac aggtctgctt gatccggagg ttgaagtccg gccaagcatg ggacaaatgg
    23641 acgacttgct tggcgagatt aacctgaggg ttgaacgagg tgagcgcacc tttatcacaa
    23701 ccttaaccaa gaaaatggcg gaggatttga ccgactacct caaggaaatg ggtgtcaagg
    23761 taaaatacat gcatagcgac atcaagacat tagagcgtac agaaattatt cgcgaccttc
    23821 gtttaggcgt ttttgatgtc ttgattggta tcaatctgct gcgtgaaggt attgatgttc
    23881 cggaggttag ccttgttgct attcttgatg cggataagga aggcttccta agaaatgaac
    23941 gaggtttgat tcagacgatt ggtcgagctg ccagaaatgc tgatggtcat gtgattatgt
    24001 atgctgatcg tatgacggat tccatgcagc gcgctataga tgaaactgct cgtcgtcgtg
    24061 ccatacagat ggcatataat gaagagcatg ggattattcc gcaaaccatt aaaaaagata
    24121 ttcgtgattt aatcagtatt tccagagcag ttgaagcaaa agcaacagaa gcagagacaa
    24181 attatgagtc aatgacgcgg tctgaaagac aagaagctat taagcaattg caaaaaaaca
    24241 tgcaggaagc agcagagctg ctggattttg aattagcagc acagcttcgt gacctgatct
    24301 tagagttaaa agcaatggat taagacctga taagctaagt ctggctgtat aagctaggct
    24361 ttttatctgc ttttgagttt gtcctttagg tctgtcttat gatctttggt accagataaa
    24421 tgagtgatat cttgagcttg atctacgcaa gagctagtgc agccactagc ttcagactac
    24481 tttaatgatt taatgaaaga ttgattttga taagacaatt ctgatataat gtaaagtagt
    24541 tggcaaaaat agaaacatta aataaatttt ctttttaata atttaacttt taccttgtca
    24601 acaaggctat tttcggatag aatttcttag tacattattt cactaataca agaaggtaag
    24661 tatgttaaaa aacaagtcaa gactgcgagc tattttcgtt tttgttggga agatagcgtt
    24721 gttttacgtg attttgatgc tgctcgttta tttttttggt tacctagggc atggtcaaag
    24781 taattttatt tataatgaat tttaggagat tgtctgatgg ttaacgatat gattgaaaca
    24841 attgagtatt ttgcacaagc acaaccggat tttccagttt atgattgctt gggagagcgc
    24901 cgtagctatg ggcagctaaa ggaggactca gatagtattg cagcccttat tgagagctta
    24961 aagctaggtg aaaaatcacc tgttttagtt tttggggctc aaagctatga catgctggct
    25021 tcctttgtcg ccttgacaaa gacaggtcat gcttacattc ctgttgatgt tcattcggcg
    25081 ccagagcgtg tcttgtctat tattgagatt gctcagccaa gtcttatcat tgctattgag
    25141 gagctgccgg ttagtattga tgcgattagg gtggttagct tagcagagat agaggcagct
    25201 aaagcagcca aggcagcctt taccatgacc agtcctgtca agggagatga caattattat
    25261 attatcttca cctctggaac gacaggacag ccaaagggag tgcaaatttc gcatgccaat
    25321 cttttaagct ttaccaattg gatgattgag gatgctgagt ttgctattcc tgagagacca
    25381 cagatgctgg ctcagcctcc ttattccttt gatttgtcgg tgatgtattg ggcgccgacc
    25441 ttagctttag gtgggacatt gtttgcttta cccaaggaaa tggtttcaga ttttaagcgc
    25501 ttgtttagca caattgcgga gctgccgata gggatttgga cctcaacacc gtcctttgcc
    25561 gacatggcaa tgcttaatga tgatttttgt caggagaaga tgccaaggct gacccacttt
    25621 tattttgatg gggaggagct gacagtatca actgcaagaa agctatttga acgctttcca
    25681 gacgcacgca ttatcaatgc ctatggtcca acagaggcaa cggtggcgtt atcagcgatt
    25741 tcaatcacta aagatatgat agagacttac acacgcttgc cgataggcta tccaaagccg
    25801 gattcgccta cttatatcat tgatgaagct ggcaatgctc tggagccggg gcaacaggga
    25861 gagattattg taacgggtcc agcagtttct aagggttatc tcaacaatcc tgaaaagaca
    25921 gctgaagcct tctttacctt taatggcatg cctgcttatc atacgggaga tttaggatca
    25981 tttactgagg acaatgtgtt actttatggt ggacgattag actttcaaat caaatatgca
    26041 ggttaccgca tcgaattaga agatgtgtcg cagcagctaa accaatcacc gctggttgaa
    26101 tcagcagtag cagtaccaag gtataacaaa gagcataagg tccaaaatct cttagcttat
    26161 gttgtcttga aggacggggt gagggagcaa tttgcgagag atttggatat taccaaagcc
    26221 attaaagcct ctgttaagga tcatatgatg gcctatatga tgccgtctaa gtttatttat
    26281 cgtgaaaagc tcccattgac accaaatggc aaaatcgata tcaaattctt gattaacgag
    26341 gttaatcatc aatgacgacc ttgtttcatc acatacctta tatggagcct tatggcaatc
    26401 cgatttattt tgtctacctc atcattgctt ttcttccagt tattattggg atctttaagc
    26461 aaaggcgttt ttcgacgtat gaaagctttg tcagcctgat ctttattttg ctcatgtttg
    26521 gtggagagca ctatcagcaa ttgcttgcct ttttagccta tctaatttgg caaaccatca
    26581 gtgttttggc ttacaagcac tatcgtcaaa aggcaaatgc agcgtgggtt ttctatctta
    26641 gcattttagc cagtctattt cctttgattt gtgtgaaggt aagcctcagt ctaacgaggt
    26701 ctttctttag cttcttaggt atttcctatt taactttcaa aagcgttggg atgatcattg
    26761 aaatgcgtga tggggttttg acagatttta gtctaaagga ttttctacgc tttatgattt
    26821 tctttccgac tttttcaagc gggccgattg atcgcttcag aaggtttcaa gaggcttaca
    26881 ccaagcttcc tagtcgtgat gtttaccttg atatgctcaa taaggctgtc atgtatctca
    26941 tgctgggctt tctgtacaag catattatct cttattgctt gggtgggctg ctattgcccc
    27001 ttgctgaaaa taaggctctg actgtaggtg gctactttaa taaagagacg atctatgtca
    27061 tgtaccttta tgggcttaat ctcttttttg attttgctgg ctactcgatg tttgcgattg
    27121 ggttgtctta tttactgggg attaagacac ctgaaaattt caataagccc ttcttatcac
    27181 caaatttaaa agagttttgg aacagatggc atatgagcct atcattttgg tttagggatt
    27241 ttgtttttat gcgattggtc catctattga tcaagcacaa gacctttaag aatcgaaatg
    27301 tgacttcggg ctttgcttac ctgatcaaca tgctggtgat gggactttgg catggcttga
    27361 cgtggtatta tattgcttac ggtctgtttc atggtattgg cttgattgta aacgacgctt
    27421 ggcttcgtaa gaaaaaggaa atcaatcgtc gtcggaaaaa gcaagggctt aagcctttgt
    27481 ttgagggtaa ggtatttcat gctttatcaa tcgtggtcac tttccacgtt gtcttgttct
    27541 cacttctgtt attctcaggc ttcttaaatg agctttggtt tagcagaccg ttacgttaaa
    27601 aaaggagagt ataaaaatgt ctactaaaga aactgtaatt gacttatttg atcgcttgtt
    27661 tatggaagac gtatcagata tgatggacga ggatttgttt gatgctggcg ttcttgatag
    27721 cctaggaacg gttgagctga ttgtagagat cgaatctatc tttaacatta aggtgccaat
    27781 ttcagagttt ggacgtgagg actggaacac tgccaataaa attattcagg gcatagagga
    27841 attgcagcat gcttaaacgg ctttggttaa tcctaggtcc tctaatcatc gcttttggct
    27901 tggtttgtct taccatattc agctttccta ctaagcttag ctattcattg cgccaggaaa
    27961 agtcaaatgc agtggcaatc aatgatagct cctttaaaaa cggcttgatt aaaaggcagg
    28021 ccttgtcaga tcctaactac tgttttgttc cgttttttgg ctctagcgaa tggagtcgca
    28081 tggatagcat gcacccatca gtgcttgcag aacgctacaa gcgctcctac agaccgtttt
    28141 taattgggaa aagaggctct gcttccttat cacaatatta cggcatgcag cagatttcac
    28201 aggaaataac tggaaaaaag gcagtctttg tcgtgtcccc acaatggttt accccccaag
    28261 gcattgatcc tggtgcggtt caattgtatc tatctaatag tcaggtgatt gatttcctct
    28321 taaaagcaaa ggctagtcat aaggaatcac aatttgccgc taaaagaatg ctggacatta
    28381 atccgggagt tgctaaatca gagcttttaa ggaaaattag tcaaggcaag gccttgagta
    28441 gatgggacat tcgtctgctc aaatggcagc aggagctgtc cttaagagag gagtccttgt
    28501 ttagcttcct tggtcgttca acaaactatg aggataggat tttgcctcgt gttaaagggt
    28561 tgcctaaaac cttttcttat gagcgcttga gcgagctagc agccagacgg gctaaggaag
    28621 gaacttcaaa taatcgcttt ggcatcaaaa atgcttttta ttctaagcga attgcaccgc
    28681 aatttcctct ttataagaat tttcagtgcc gtaataatta cactgtgtca cctgagtaca
    28741 atgattttca gctggtattg tcagaatttg caaaacgtaa aacagaggtg cttttcgtta
    28801 ttacacctgt taatcaagcg tgggcaaatt atacaggctt aaaccagagg aggtatcaaa
    28861 aggctgtcag aaaaataaag catcagttaa cctcgcaggg ctttactcgc attgctgatt
    28921 tttccagaaa tggcggagac aagtatttta tggaggatac cattcacctt ggctggaatg
    28981 gctggctagc ctttgacaag gaggttgttc ctttcttaga ggatcaaaca ccaccatctg
    29041 aataccaact ggatccttac ttcctatcaa aggactgggc agatagaaca gcaggatttt
    29101 agggtcaata gaccattaga aaatgaggat tagaattgtt aatgagtatc atcgtcatat
    29161 tgcttatttt agccattgct gttttagtga ttgagtatgg tcaaaagcgg tccttttcta
    29221 gctggctgct tgaaaagatg tttgattatc gtaagtataa gctctctaaa aaggctgatg
    29281 actatgaagg aattgagacg caaagacgtc gtcgcattcc ctaccacttg gataatccag
    29341 aggcggtatt ggggattccc accacagaat atacgattga tggcatgcag gtttttgtga
    29401 tcaatgacca agattctcag gatcagccag tgatttacta tctttatggt agtgtctatt
    29461 tgcgtcgacc tgagacattt cactttaaaa ccattaagca tttgatccat ttaaccaatg
    29521 ccaagctggt gttcccaaat tttgagaagg cgccttatgt cacctataag gagatttacc
    29581 caaagcttgc taaaacttat caggagcttt gtctagccaa tggcgctgcc aaggttagca
    29641 ttattggtga ctcctcaggt ggtggcatgg ccttagcctt ggcgcaatac ctaagagata
    29701 cccaaactgc accacagcca aagcaattaa tcctgttatc tccttggtta gatgttagct
    29761 ttgctaatca ggattataag cattttgaag cagtagaggc ttatttagat gctaggcggc
    29821 ttcgagacat tggtgaattg tgggcaggca gtccagaaga aatgcggtct ccgtatgtca
    29881 gcccattata tggcgattat catgacctgc caaagattgt cacttttgtc gggacaaaag
    29941 agatttttta cccagatatt atgaccctgc atgagcgctt gatggagcaa gggcacttaa
    30001 atcagctcgt tattgctgag cagatgattc atgcttatgc gatcttcccg atacgagagg
    30061 caaggcaggc gcgcaagcag attgccgagc tgattttaaa gaaggagtga ttgttgctat
    30121 aggagtcagt tagccttgct tgtctgatga ggcttgggct tgagatttct agagaagctt
    30181 taaggccttt acttgggctg ttaatgctca ttaaagagga ttataggctt tatactaggg
    30241 cttaggattg ctgttttgct attcaataat attagtttag acttgattga ggaaaggcta
    30301 gttttagtta tggtcctcaa tctttttttg atggtaaaca tgtcaagaca gtttacttgc
    30361 tagggtaata atcctgtgct catttcatga gtggctattt ttatcctaag cttggtggtg
    30421 gaaaaatcag attaaaaaat atgaaatttg ctattgacag ctgtaagcga ttgcattata
    30481 ataaacttaa cttaaacgtt taagttaagt tgaataagct gatttgatca tgcactgcct
    30541 aaatgcaatc aataatctca aagcatttgg tgtagtctag taatcaatga ggcagtttat
    30601 tacggttata caatatttat ttagttcatc cctttaggag gtaaatagct atggcgtggg
    30661 attggaaaaa agcaggtgtt gttggagtag tgtcattggc ttcgatcatg gtattaagtg
    30721 cttgtagcgg aggacatcaa aaagaggcta agcaaaaaga cgacaatacc attgtagttt
    30781 cagttgatga gggctatgca gactacatca aagagattaa gacagccttt gaaaaggaca
    30841 ataaggtcaa ggtcaaggtc aaaaaggaag gtatgattga tacgctagat aagctatcta
    30901 ctgatggacc gacaggtgct tcaccagatg tctttttagc accatatgac cgggttggtg
    30961 ggcttggctc tgaagggcaa attgctgagg tgagcttagg caatgctgac cagtttgatg
    31021 acactgttaa aaagctagtc accataaatg gaaaggttta tggggcacca gatgttattg
    31081 agaccttagt gatgtattat aacaaggatt tggtatcaga ggctccgaaa acctttactg
    31141 acattgaaga gctaaataag gatcctaagt ttgcctttgc ttctgaagac ggtaagtctg
    31201 taggctttct tgctaagtgg acagacttct attatggcta tggcttgatt gcaggctatg
    31261 gggcttatgt atttggagat aagggaactg atccaaagga tttaggtatt ggtaatgctg
    31321 gtgccattga aggcttagac tatgctaaga aatggtatag cgtatggcct caaggcatgc
    31381 aggatactca aaaggctgga gattttatta cagagcaatt cacctctaaa aaggctggtg
    31441 tgattattga tggaccttgg gctgctgcct catttaagga ggctggtgta aactttggag
    31501 tggcacaaat tccaagctta cctaatggcg gtagctatca agcctttggt ggtggtaaag
    31561 catgggtgat ttcaaattat tctaagaata aaaagctggc acagcaattc cttgattatg
    31621 tgacaaatga gaaaaaccaa aaagcctttt atggtaagac acaagagatc cctgccaatc
    31681 tagctgctcg cagctatgct gcagaacaag gaaatgaatt gacaaaggcg gttattgggc
    31741 aattctcaaa tgctcagcca atgccaaata ttccagaaat ggcagaagtt tggggaccag
    31801 gtgcgaacat gttctttgag gtagcagcag gcaagaagac tcctgccaag gctgctaagg
    31861 aagcagctaa aaccattcaa gaggctattg cacaaaaata cactgaataa cataaaaagg
    31921 gaggctggga taaaggtatc ctagtctcca tcttgttacc tatagtatca gagtgggcga
    31981 tgaggagata ataataaaaa gtagtagtga ctagcttgtc ttgtttccca tcttgtccta
    32041 ataagagtat ctgataagac tgatgaacct agggaggaaa aaatgaacac agccggaata
    32101 ctgcatattc cagattctag atattgcttt gccttatcaa caaaggagct tgtgattcgg
    32161 ttgagggttg caaaggagga taacgatata gcggtgacgc tggtttatgg acctaagtat
    32221 cattatcatg agtatcaaaa agaactggcg atgtatgctg cttataccga tcatacccat
    32281 acctattatg aaatcacctt aagtcttgat gatgttagat tggcctatat ttttaagctt
    32341 gagcaatctg gtcacaccta ttactttagt gaggatggct tgaccacaag ctatgatttt
    32401 tcaaatggct tttacaactt ttttcaaatg ccttatatta atgctgtaga cgttcatcag
    32461 actgtccctt gggtgcacaa tgctgttttt tatcagatct ttgttgatcg ctttcatcgt
    32521 ggtgactttg aaaaggacga tagctatatt aatatggctt ggctggatag gccaactcct
    32581 aatagctttg ccggagggga tttgaagggg attacagata agctggaata ccttgaggat
    32641 cttggtatta atgtcattta cttgacaccg attttcaaat ccatcagtaa tcacaaatat
    32701 gatattagtg actactatgc tattgacccg atgtttggga catcgcttga tctccagcaa
    32761 ctaataaacg aggcccacca aagagggatt agaattattt tagatgctgt tttcaatcat
    32821 gctagcagtg attgcgagcc atttcaggac gttttggcac atggtagtgc ttcttcattt
    32881 tttgattggt ttatgattca aggagatcat ccttctgtag agctagctaa ttacgaaacc
    32941 ttcgctgatt gtcactacat gcctaagtgg aatacctcgc atcaggctgt tcaggattat
    33001 ttgattgaga ttggtcttta ttggatcaca gagtatcata ttgatggctg gcgattagat
    33061 gtttctgatg aggtatcgca tgatttttgg agacgctttc gaaaggctgt taaggcagtc
    33121 aaatcagatg cgatacttat tggagagaat tggcatgatg cttatcccta ccttcaagga
    33181 gaccagtatg atggtattat gaattacgcc tttaccaagg cttgtctcga ttattttgca
    33241 tttgatgcga ttagctcaca ggaaatggct gaaagattgt cgcatatttt aatgagaaat
    33301 acttggcagg tcaaccagat gaatctgaat ttactggatt cccatgatac gcatcgcttc
    33361 ttgactcagg tgaatggctc taaggacaaa ttattggctg gcttagccct tttagttacc
    33421 tttatgggca taccatgtat ttactatgga acagagcttg cgatggaggg aggttatgat
    33481 cctgactcta gacgtagctt taattgggac agcagcactt gggatatgag cttttggaat
    33541 caggttaagg acattatcag cctgcgtcgt catgcggtta tccaatttgg aagcatttcg
    33601 ataacctccc atgatgactg cctttgcgta aagcgtgaat taaacggtca atcgataaga
    33661 ttgctggtta ataatggcgt taagccatat cctattgaga aaggaggttc tgtgcttgtt
    33721 tctaatggtg tagataaaga gacatttgag ctactccaga acgggtttgt tgttagctat
    33781 taatatggcg ttttatcaaa ggaggttaag gatgaagcgt attactttaa catgtcgtaa
    33841 agcattaaca gtagctatgg cagcggttac cttagcaatg tcaactaaca gtgtctttgc
    33901 tattgaaaat actgcggtgt ctaataaggc tgatttttct actgacacga tttatcaaat
    33961 tgtcaccgat cgttttcatg atggtaatgc tgctaataat ggaaatacag atgtatttga
    34021 taaaaatgat cctaaaaaat atcatggggg tgattgggca ggtatcatta agaaactaga
    34081 agatggctac ttaaccaatt taggggtatc agctatctgg atttcatcac cagttgaaaa
    34141 cattgatacc attgaccctt caaatggcag tgcagcctat catggctact gggcaaagga
    34201 ttttttcaaa gcaaacagtc actttggaac aatggaggat tttaaaaagc tcattcaggt
    34261 ggcacatggc aaaaacatta aagtagttat tgattttgct cctaatcata cctcaacagc
    34321 agaatataat ggcttaacct tccctgagga cggtgcttta tataaggacg gccagctggt
    34381 tggtaaattc agtcatgatg atcaaaagat tttcaatcat gaatcatgga ctgatttttc
    34441 aacttatgaa aatagcattt atcattccat gtatggcttg gcagacttga acaatctgaa
    34501 tccaacagtt gacgattatc tcaaagaggc tattgataaa tggttagaaa tgggcattga
    34561 tggtattcgt gtagatgcgg tcaagcatat gtcacaaggc tggcaaaaaa attggttgag
    34621 tcatatctat gagaagcata atgtattcgc ctttggggaa tggtttgctg acggttcttt
    34681 taatgatcca ttgatgacta aatttgctga tactagcggc atgagcctgc ttgattttag
    34741 gtttgctaat tctgttaggc gcctgtattc tgatttatca gcgaaaatgc aagattttta
    34801 caatatgatt gtagctacgg aaaaagagta caaggaagtt tcagatcaag tgactttcat
    34861 tgataaccat gatatgaccc gctttgctac tctagtcaat cataatcaga cagctgttaa
    34921 tcaagcctat gctttactgc taacatcgcg tggtgttccg aatctttatt atggttcaga
    34981 gcagtatgct acaggtgcta acgaccctga aaatcgtggt gatatgccaa cctttgataa
    35041 gaattccact gcttatcagg tgattagcaa actagcacca ctgcgtaaga aaaatcaagc
    35101 cctggcttat ggtacaacac agcagcgctg gattaatgat caggtcttgg tctttgaaag
    35161 aaaatttgga aatgacgttg ctttagtggc tgttaataag gatcaaacaa atggctacac
    35221 aattagtggc gctaaaacgg ctttaccagc tggtaagtat gctgatgaat taggtggctt
    35281 actgggcgga aaggaattaa cggtatcagc tgatggtaat gttgaggcat ttgagttagg
    35341 tgcgggtcag gttgcagttt ggacctttaa agggcaacat gagacaccgc agataggaga
    35401 cgtagacgct tcgtttggcg ttgcaggaaa tactgtctct atttcagggc aaggatttgg
    35461 tagtgctcaa ggtcagcttc attttggtga tagcaaagca gatattgtgt catgggacga
    35521 taccttgatt caatttaaga tacctgctgt agctgctggg aaccatgata ttaaggtgac
    35581 cacatctaca ggacaaagca gtagccctta caaagccttt gaagtgttaa cagataagca
    35641 aattccagta agattggtgg tcaataattt caacactgta ttaggtgagc agctttatat
    35701 cgttggtgat gtggttgagc ttggggcaaa tgataatcat aaagctttag ggcctatttt
    35761 taatgcaaca cagtcaattg cgcagtaccc aaattggttc tatgatgtca atctgcctat
    35821 taacaaaacc attaactgtc atcttgtaaa gaaggatagt tctggtaaag tattgtggac
    35881 tagtccagaa acctatacca ttaaaactga tagcaaggct caaaccattt cattgaaaaa
    35941 atagttgcgt tatctgtgat gttatttaat actctatgaa ggaggagaac cataaaaggg
    36001 tgatagagag gaatgacaaa tgcttaagaa tgaaaaaatg aagaatccac aaaaagccat
    36061 gtggctttca ataatccctg gtctggggca actctacaat actcaaaagg taaaaggctt
    36121 tattttgctt cttgtgtttt taggtgagct gctagaggct ttctttgttg gtattccggc
    36181 tcttgctggc ttgtacagcc ttggtagtgt accaatggag gatcattccc tattcttatt
    36241 gattaaggga gctatgcagc ttatcctatt tgccttgttt ttgatctttc atttggctgc
    36301 tatgcgagat gctagactag tggcaaggga gatcaatgca ggccatagca tttcattaac
    36361 cttaaaggag atggtacaat ccatctatga aaagggcttt ccttatttgc tgattattcc
    36421 agcctacttg gccatggcct ttgccattgt ttttccggtg cttgttactt tattaattgc
    36481 atttacaaac tatgatttta ggcatattcc tccctataaa ttattagatt gggttggcat
    36541 taagaatttt aaaagcattt tagagcttag cacctttaag tcagcctttg gctctgtgct
    36601 gtcatggacc ttgatttgga ccttggcggc aacgagtctc cagattgtga taggaatagc
    36661 gactgctatt attgccaacc agtcctttgt gaagtgcagg cgcatttttg gggtgatttt
    36721 cttgctgcct tggggggtgc ctgcttttat ctcgatcatg agctttggta atttctttaa
    36781 tgattctatc ggtgctatga atgttcaggt cttaccattt ttagaaaagt ttgtgccatt
    36841 tgcagatttt gggattatcc catggaagac agatcctttt tggacaaagg ttgcggtgat
    36901 tatggttcag ggctggctgg gctttcctta tatttatatt ttggtgtctg gtattttaca
    36961 atcaattcct gctgatttgt atgaggcagc aacggttgat ggtgcaacag ccctgcagaa
    37021 gtttcgccaa attaccttgc caatgatctt tgctgtcgca gccccgacct taatctcgca
    37081 gtataccttt aattttaata acttctccat tatttatctc tttaataatg gaggtcctgg
    37141 tacagttggc ggtggcgcag ggtcgacaga tattttgatt tcttggattt acaagctgac
    37201 cacacaaacg tcaccacagt tttccattgc ttcagcggtg accttaatca tttccttgat
    37261 tgttatttct gtatcattga taacctttaa aaaattcaaa gcctttgaca tggaggatcg
    37321 ctaaatgggt aggaattatt tgccacagtc agtgaagaag aagcgcttgt tagctcagct
    37381 gttgacttac agctatttgc taatcctgtc gatcatcatc ttatttccaa tcttggtgac
    37441 cgttagctca gcctttaggc caggaaatac aactgccttt agctttcata ttgatgggcc
    37501 ttggacctta tcaaactttg agacactctt tcaggacacc tattacttaa gatggtactg
    37561 gaacacgtta gttgtcgcct ttttcacgat gctgatccag gtgacagtca ttacgctgac
    37621 aggctatgct tacagccgtt atcacttttt tgggcgtcaa aagagtttgg tctttttctt
    37681 agtggttcag atggttccga caatggctgc cttaacagct tattttgtga tggcttggtt
    37741 gtttaatgct ctgaatcact attggttcct cattctgatt tatgttggag gaggcattcc
    37801 gatgaatgct tggttgatga aggggtattt tgatactgtg ccttatgatt tagatgagtc
    37861 agctaagcta gatggctctg gtcactttag gaccttctac caaattgtat ttcctctggt
    37921 tcgtcctatg gttgctgttc aggccctatg ggcctttatg gggccatttg gtgactttat
    37981 gcttgctaag tttctcttgc gtgaacagga gcattacacc gtagcggtag gtcttcagtc
    38041 attcatcact aacgacgcta gggatcctaa ggtcacattg tttgcagccg gggccatttt
    38101 aattgcagtg ccaatttcag tgctattctt ctttttacag aagcattttg tttcaggctt
    38161 aaccaatggt ggaacaaagg gttaatttat ctttcaagga gcctttatca tgactaatga
    38221 tcgatttcct atttcttaca caaccattat tttttctcct aaaatgatat ttgctcgttg
    38281 cagtgccttt ttgtggtggc agaatgtgat tttagtgatc tttctaaatg ctctggtgtt
    38341 aatgccgatc acgctgcatt atgcaagctt gaagagctat cccttagagc acatagttag
    38401 taatggttta gactccttga cagaaaaaac ctatcatgcc ttgacacaag gcactatttg
    38461 gcatgatcgc tatgatggaa aaacagtcct tatagaggat actgatgctg ttgttgctgt
    38521 attgccaaca ccagaaatag tagaagagct aaagaaagat caaagaagcc agctgatatt
    38581 aacagaaacc tcatggattt taagctttcc tgatggtcaa aggctaactg ctaaggttaa
    38641 aggcaacaag gaaaggctaa cgcgcttaac ctctctagag gctgtcaagg cctttgttaa
    38701 tcagcaatgg tacaatagca atcgtgccgc tgtgcttgcc tttttgctgc tagtggctag
    38761 cagtgtggtc tatctaggag ccggtttagt gatcggaatt ggctcgttat cactgttatt
    38821 aacaagatct gctagattat tttcactcaa gagctactca gaatgcttgg gtttgctagt
    38881 gaattgcttt ggacttccta cgcttttagc agtgcttata agtttttggg tgcacaatcc
    38941 tattgttatc atgaatagtc aggtctttgg cacactgctc atgctggttc tagtctttta
    39001 caaaactcag tttagagatg aggagcaagc actagcttag cccttgctga catcaaaaaa
    39061 tccctccc
//
LOCUS       DARYLD010000015        38024 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYLD010000015 DARYLD010000000
VERSION     DARYLD010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38024
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(80..1285)
                     /locus_tag="TU651_000644"
     CDS             complement(80..1285)
                     /locus_tag="TU651_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL0896667.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(1538..2791)
                     /locus_tag="TU651_000645"
     CDS             complement(1538..2791)
                     /locus_tag="TU651_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL0896668.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(3188..3808)
                     /locus_tag="TU651_000646"
     CDS             complement(3188..3808)
                     /locus_tag="TU651_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896669.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(3849..3944)
                     /gene="ffs"
                     /locus_tag="TU651_000647"
     ncRNA           complement(3849..3944)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TU651_000647"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            4121..5347
                     /locus_tag="TU651_000648"
     CDS             4121..5347
                     /locus_tag="TU651_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0896670.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(5457..5951)
                     /locus_tag="TU651_000649"
     CDS             complement(5457..5951)
                     /locus_tag="TU651_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL0896671.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(5948..6730)
                     /locus_tag="TU651_000650"
     CDS             complement(5948..6730)
                     /locus_tag="TU651_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0896672.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(6829..7368)
                     /locus_tag="TU651_000651"
     CDS             complement(6829..7368)
                     /locus_tag="TU651_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL0896673.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(7372..7683)
                     /locus_tag="TU651_000652"
     CDS             complement(7372..7683)
                     /locus_tag="TU651_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896674.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(8070..8207)
                     /locus_tag="TU651_000653"
     CDS             complement(8070..8207)
                     /locus_tag="TU651_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0896675.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(8591..9835)
                     /locus_tag="TU651_000654"
     CDS             complement(8591..9835)
                     /locus_tag="TU651_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0896676.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TU651_000655"
     CDS             complement(10265..11407)
                     /gene="tgt"
                     /locus_tag="TU651_000655"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL0896677.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            11812..12657
                     /locus_tag="TU651_000656"
     CDS             11812..12657
                     /locus_tag="TU651_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL0896678.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(12853..16815)
                     /locus_tag="TU651_000657"
     CDS             complement(12853..16815)
                     /locus_tag="TU651_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL0896679.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(16950..18776)
                     /locus_tag="TU651_000658"
     CDS             complement(16950..18776)
                     /locus_tag="TU651_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL0896680.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKA
                     ADKQQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(19136..19609)
                     /gene="perR"
                     /locus_tag="TU651_000659"
     CDS             complement(19136..19609)
                     /gene="perR"
                     /locus_tag="TU651_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL0896681.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(19646..20098)
                     /locus_tag="TU651_000660"
     CDS             complement(19646..20098)
                     /locus_tag="TU651_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL0896682.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(20338..22980)
                     /gene="polA"
                     /locus_tag="TU651_000661"
     CDS             complement(20338..22980)
                     /gene="polA"
                     /locus_tag="TU651_000661"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL0896683.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(23404..25134)
                     /locus_tag="TU651_000662"
     CDS             complement(23404..25134)
                     /locus_tag="TU651_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL0896684.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKHKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(25152..26348)
                     /locus_tag="TU651_000663"
     CDS             complement(25152..26348)
                     /locus_tag="TU651_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL0896685.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(26548..26790)
                     /locus_tag="TU651_000664"
     CDS             complement(26548..26790)
                     /locus_tag="TU651_000664"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896686.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(26855..27946)
                     /gene="ulaG"
                     /locus_tag="TU651_000665"
     CDS             complement(26855..27946)
                     /gene="ulaG"
                     /locus_tag="TU651_000665"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL0896687.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(28141..29787)
                     /locus_tag="TU651_000666"
     CDS             complement(28141..29787)
                     /locus_tag="TU651_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL0896688.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(30091..30807)
                     /locus_tag="TU651_000667"
     CDS             complement(30091..30807)
                     /locus_tag="TU651_000667"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL0896689.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(30807..31670)
                     /locus_tag="TU651_000668"
     CDS             complement(30807..31670)
                     /locus_tag="TU651_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL0896690.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(31675..32340)
                     /locus_tag="TU651_000669"
     CDS             complement(31675..32340)
                     /locus_tag="TU651_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL0896691.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(32435..32920)
                     /locus_tag="TU651_000670"
     CDS             complement(32435..32920)
                     /locus_tag="TU651_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0896692.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(33136..33414)
                     /locus_tag="TU651_000671"
     CDS             complement(33136..33414)
                     /locus_tag="TU651_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0896693.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(33529..34962)
                     /locus_tag="TU651_000672"
     CDS             complement(33529..34962)
                     /locus_tag="TU651_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0896694.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(35445..36065)
                     /locus_tag="TU651_000673"
                     /pseudo
     CDS             complement(35445..36065)
                     /locus_tag="TU651_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(36067..36684)
                     /locus_tag="TU651_000674"
     CDS             complement(36067..36684)
                     /locus_tag="TU651_000674"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896695.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(36671..37459)
                     /locus_tag="TU651_000675"
     CDS             complement(36671..37459)
                     /locus_tag="TU651_000675"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896696.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(37530..37931)
                     /locus_tag="TU651_000676"
     CDS             complement(37530..37931)
                     /locus_tag="TU651_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896697.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        10972 a         8905 c         7422 g        10725 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccactt gttttctgac tagtctcttc caaagacatc tctcgtgtaa accttgtcaa
      121 tgacatctgc taggtcgtcc tcaaagcgat ttgacacaat gattgtagac tcgtttttga
      181 actgctctaa atcctttaca actctatagc caatgtcctc accaagcatg ggttcgtaaa
      241 tgacaatatt aaccccatag tcgttgatga tatcaataat atctttaatg gcgctttctc
      301 ggaaattatc agagttgctt ttcataatca agcggtaaaa gccaatcgtt aatggtacac
      361 cagcctgctt ttgactagag gctctgtcta atatttgttc agccaaataa gattttcgta
      421 tcttgttgga ttcaacaatc gctgacatca aggactgggg aatgcctcta taatttgcca
      481 acagctgctt gctgtccttt ggcaggcaat agccgccata tccaaaggaa gggttattgt
      541 aatggttacc aatgcgctga tcatgacaga ctccttcaat cacgcgctga gcatctagac
      601 ccttgctttc ggaataggtg tctaattcat taaagtaaga cacccgcata gccaaaaagg
      661 tattcgcaaa tagcttgacc gcctcagcct cctgtgagcc cataaataag accggagtat
      721 ccttgctttt ggctccttcc tttaaaagac cagcaaaggc tttagcagcc tgaataaccc
      781 ttggtgagtc gtccttttca taagaaacaa tgattcgact tgggtaaagg ttatcgtata
      841 aggcttttga ttctcttaaa aattctgggc taaaaataat acgatctgtc tggtattttt
      901 ccctaacatg cttgataaag cctagtggta tggttgattt gataataatg gttgctgacg
      961 catttaggtc taggacctgc tcgatgacct cttcaacatg ccttgtgtca aagtagttgc
     1021 gttcgctgtc ataatttgtc ggagtagcaa tgataataag gtctgcattg ctataagcgc
     1081 ttgcgccatc aagcgtcgct gtgagattta gcggcgcatt ttttaaatac tcctcaatat
     1141 cagcatcctt gattggcgat atgccttgat tgatcaatct caccttttca tcaataatgt
     1201 caacaacagt gacgtcatta tgttgtgcca gtaaaatact caaggatagg ccgacatatc
     1261 ctgagcctgc tacagaaatt ttcacttcat tttttccttt gataccttag tacagttagc
     1321 tactgccgga gctcaggtgc cacacctgaa ggaccatgat gacctagccc tcataccaaa
     1381 gctgacgctc agcctctggt tcgtcttcac agggctacaa gctaaaagct cttaactcaa
     1441 gtacaagtgg actagcttta tttgatgagc tgcttaactc aagatgcttt gttcactcct
     1501 agcttagctc ccttgtcaga acctaggtct agttggttta taataatttt ttacgtgttc
     1561 cccagtcagc atttctaata gtaaaaagag aatacaattt caagggctgt aggacaaaca
     1621 aatgcagcac cccataaaac ggagataaca agaaggacag cgggtgctta agcatgtaat
     1681 gaatgttccg acaaagagca acaatgaaga taatcaccag aaaggctaaa accctgagcc
     1741 aatcaaattc tctgacattg cctacaaaga aatccaccac agaataaaca agcatcataa
     1801 acatagacac ctcaagtatg gtccataggg ctacaaaagg attgttcatg attttcttaa
     1861 cagaaataat ggactctcta aagaaggact tgttccagcg gttttgctgc ttcaagtaag
     1921 tagacatctt gtcaggaaca tctgtaatac atttagcagt ggattgataa acagtctttc
     1981 ctaaatcagt tgcatagttg gtcaagcacc tgtcatcacc gatacttaca ggaataccca
     2041 ggaaggtctg gttgatgtat ctgtctatat taggaacaac cacctcgcgt ctgtaaacgc
     2101 taagtgggcc tgagcaaaca aggatattac ccgtaactga ttgggcagct cgttcaacgc
     2161 caaaagcatt atcatagcga atatctgtca agcgtgttaa gagattggtt tgtctatttc
     2221 tgacattaag gtgacccgtc gcagcaaaaa cagttgggtc attaaaggtc tttaacagct
     2281 cctctaaagc atcagggtag atataagtat ctgagtcaac ggtcaaaaag acatcagcgt
     2341 ctgatctttc aaaggcccag gcctgtgcat gacgctttcc ttgatttttc tctgaccgat
     2401 gaacaatgac attgcttgat aggtcaccag tgtcacgcac atagtcttca atgcgcttaa
     2461 tacctgtctc atcagcactt ccatcgtcaa caacataaat ttctgctagg ggataggttt
     2521 gctgctgaac actttttaag gtctctagca atgactcagc gtcttcgtta taagagggaa
     2581 taatggctgc aaccttatat tgcccagccc ttcccttaaa tggcttgtaa aaaaaagata
     2641 aggacatttt gactaataga taagctatca gcaaaaagcc ataaattgac aagcttcctt
     2701 tagcaccaaa gagataaaca ttgacgtaaa tcaacagtac ccaaaaaata ctaaaggcca
     2761 caacagttat gaggtttttt aatgttctca ttgtgattgg tttgctcctc tcttgcgctt
     2821 tgtattttgc ctttaaacac taaccataat ataccatctg tcacagcaag caaacaaggt
     2881 cattaattta ccattctatt aaagatagat taatcttagt gtcaatacag ctttttctaa
     2941 gatttgccta tgctcaccaa gtcatcaatc ccctacaaaa aacaaatgat agcctgagtc
     3001 tacctgtggc tatcgctagc atgtgcctga taacaagcag ctaaatggcc cgtccaaaac
     3061 taaggcgctt tggacagccg cttttcgctc tcttttttga catcaaaaaa gcagccctta
     3121 tcaggccact tcatattggt aacaaagcaa ttctataagg agctccttaa aggataaggg
     3181 caagagatta ctttagagac ttgatgatct caatgcgagt gataaccccc tcatgcatat
     3241 gatctactct taaggcaaca tcagaaaaag caatagatgc cccaatcgtt gcagtctttc
     3301 cttcctcttc caaatggcgc agcattaaat cacgcattag ctcgtttttg ttaataaccg
     3361 gcagctcgac acgcgctagc acattagcta ttttgacctt ttgactgccc cgaacgataa
     3421 tgcttgaagt atcatcaaag cttgtaaaaa ggtattttcg cgtcgcaaat aaaatagcaa
     3481 gagctatgac actcaacaaa gaatccttag cagagccatg agcgacaaca atttgccggg
     3541 caatcgcaaa caaaagcacc tcaataatgg ttcctgaggt atgcttactc agcattttaa
     3601 tcagctcgac accaatagca atactcatgg cctggtttaa aaagctctgt aaataggtat
     3661 caatgccact ttttatggta aaaatacctg tcaagctcaa ggccaagcgc cctgtcagca
     3721 ctagtaacga aatcaccaag atgatggaaa taataatctc aacataatga gatagctcat
     3781 acaatctaat ctgcaaatat tttctcatag caactcctta tcattattat ataaaaaatg
     3841 ccactatttg aaaataaaaa aagagcacac acccgatatc gcttagggct gctggattcc
     3901 tcccctgacc cacttcacgc acaagtgttg ctccaccttt attgtagcat atattgtacc
     3961 ctaaaacaag tcttatttca aaaacgtctc acatctggct cataaagctt aattagctca
     4021 acagcaaacc aagcaaacgc tatcaataag gccagtcctt aaagctaagc ccgactagac
     4081 ttgtgctata atggtactaa caaacctgag tggagatgat atgaaaaaca agcttagcct
     4141 attcttgctg gcagcactta ctatagtcgg tctctcagcc tgtgcatgga gatccaatcc
     4201 tcttgctgac aaggagcagc agttcggcct gactggagca agacgtcagc aggtgcttga
     4261 tcagatcgat caacgttatt attaccagca gcttagtcag gcagaaaagg aaaattacct
     4321 tctcttgtat gatagcctct cagcctttca cgaggtgact agcctagcac cagcttctaa
     4381 gcatagcttg atgacaacca ttgatgcctt tatgatggat aatcctgcct ttttctggat
     4441 tacctcagcc aactaccgct tggaacgctc ggatcaggtg gccttcgtta cctttccatt
     4501 gccagagaag gtcgaacaaa catatcacag gcttcaagcc attggagatg atatcatcgc
     4561 tgacatgcca gcaaccaatg actatgagcg cgtgaggtat ttttatgagt ggatcatcaa
     4621 gcaaactgac tacaatagag atgcctttga ggcatatcaa tcgggtcatg aggccttgat
     4681 agcctctaat caagacattc gcagtgtctt tcttgatcat ctttctgtct gcaacggcta
     4741 tgcacaggcc tttcagtttc tttgccaaaa ggccggtatt cctgtcgcct atattcgagg
     4801 gtcagtcacc tttgatcgat cacaggacgt ttttactcat gcttggaata ctgttcagat
     4861 tgcaggcaag aactatgctg ttgacacaac ctttggagat cccgtctttg atcaaaacga
     4921 atccattaag caactagagg ttaattataa ctttttatgc ttgccagacc agctcatgaa
     4981 gcagtcgcat caagccagca gggatattgt gatcaatcag acagaaacct tgaccgatgt
     5041 ctggacaatt cctgagtgct cagacgattc tctgctctat actaagctca atcacagcta
     5101 ctttactgcc tttgatagac cagacattct ggccagtctt gagcagcaat taaggactaa
     5161 tcagccacag accagcttac aatttgctaa tcaggacctc tacaaccaaa tggtaagtga
     5221 tcttgagcag cattctgaca gctaccatag cctgtttcaa gcttattggc ctaatgctgc
     5281 tggctatttc tacagtctac accccagcac ctttagcatt agcattagca ttatcaatca
     5341 gcaatagcct aataccctga cagacaagta caagcgctta tggcatggct ctaccagcca
     5401 ttaaagagct gtgctaggct ctcaagggtc ttttttcttg ctaatcgctc aatgggctaa
     5461 atcttacttt ccttatcctg ctttttctgg tcacgccttt gccggaaaaa ggtctgcatg
     5521 agcttggcac agtcatcagc taaaagacct acctcaagct gtacacgatg gttcaggcgc
     5581 tcatcggtta agatctgata aagactacca gcaccgccaa acttttgatt gctggcccca
     5641 tagaccacat gaggaattcg agctagccca atggctccgc tgcacatgac acaaggctca
     5701 atcgtcacaa aaagagtcgt atccaagaga cgccaattgc cttcgtgcgc attggcttca
     5761 ttaatggcca tgatctcagc atgcataatc gcctgattgc gctcctcgcg agcattgtga
     5821 ccacgcccga taatgtgacc agccttcaca ataacgcagc caatcggtat ctcgtccttt
     5881 agcagcgatt tctcagcctc cttgagggct tctcgcataa aatactcttg ctcttgtttg
     5941 gaatagctca ttgagataga ctccccaaat cccaagcccg atgtggcaga gcaagatcaa
     6001 caggaatctg accagcatag ccttgagctt gctgtcgcag cacctccaaa tgcctcttag
     6061 gatcaatccc ctctggcggc agaggtggca tatgggtcaa gaccaagcgt ttcaccttag
     6121 cacggctggc aagctgccca gcctcttttg aggtcaaatg cgccatatga tgttcattgc
     6181 cttcataaag gtacacatct gctaaaaaca catcagcctc cgcagcaaaa tcagccagct
     6241 cttcaaagta gcctgtgtct cctgtaaaga caagcacctg cccagttgct ctttccacaa
     6301 tacgaaaagc atagcacacg accgggtgaa ccgtcttaat aaaggtaatg tcaaaaggtc
     6361 caagagcttc aaccctatca acctgatagg caatgccctt tgagacacct ggcaaggtta
     6421 gtttggcaaa ctcggcctca tcttcgtcat gaccgtaaat aggtagtagc cttggcttgc
     6481 caagatgcct tggatagagc tgataataat gacgcaaaac acccaagtct gccacatgat
     6541 ctggatgata atggctaatg ataacagcgt ctaaatccag cggattgatt tctttttcta
     6601 attcgttaag agaacgacta ccagcatcca tcaataattg aaaaccatca tgccctgtca
     6661 caagataggc tgtcgtccca gcatcttgat agggataggc tccccaagag ccaagcgttg
     6721 ttaatttcat cacaaaacct tccttcatgc tttgttctta ttataacaaa aaatagcagc
     6781 aaaaaataag tcctagtgcg caagagctag gacttacagg cttagtattt agctgttggt
     6841 gtttaaaaag ctgtctttat agctaacagc aagcgccgtt gcgatgactg ccttaatagt
     6901 atctcccggg ataaagacaa ggctagcaac gagcgatcta gtgagcggca tgtctgtata
     6961 aaccgctagc caaatagtcc ccaacagatc caccagcagg acaccagaaa taaagattgc
     7021 taaaaaagca agagaccgat accttgctag ccagctgcgg tacaagaatg caaaaaccaa
     7081 tggaacaaag agccaggcca aaacatagcc agccgatggt cccattagga ctggaacagt
     7141 tgttctagag cctgaaaata ctggcaagaa cagaccaatc actagaaaaa gcaggataga
     7201 cagggttcct tttttcccac ctaaaatcaa gccagcaagc atgaccccta agttttgcaa
     7261 aacaatcggc actggaacaa agcctagagg aatcgctgga ataagaccta aaataatgat
     7321 taaggtggtc atcattgcta ccttcactaa gtccttggtt gacaacatat ctcataactc
     7381 ctttgaaaaa taaatatcct gatgcttatg ataggctggg ttaaaagggc taaaacaaaa
     7441 aggacagctg ccgcactcat attcggacct tctcagcagt tgtcggcaat gaccacaaat
     7501 caccggatag gtctccttgt ggtctgtcgg ctcaaaagca tgatcttgaa gcgtgtcatg
     7561 acaatgataa caggcataat aagcctgaca tcgagcacac ttcaagccga caatatccag
     7621 cactgtgtga taatgtacac agcgatactc ctgatcaagc gcgataccaa aacagttcct
     7681 catgtcttat cctcttatta aaaggataaa gcattcgttt tattttgtca acctatattt
     7741 actaataggg ttactaatca cataagaaga acaccaaaaa agcataaagt agtcccatag
     7801 gcagctgctt tttaccagta ccacacaaat agctatatga ctataaaggt tggcttaaga
     7861 aggttcagat ttaaccgagt gtgggaaaaa gattaccaat ctagctgcca aaatacgggg
     7921 tctcgtttga ctatttttcc ctattgggat ataatgagaa cagaaaaagg gcagttgctc
     7981 taaacaacta ccctatgcag aaccgtttaa gacggtggca tatctttaat tattaaaaaa
     8041 taatcgtcga cctaccaaag ttcagacggt tattttttat tgtttaatat gacgattgca
     8101 acgactaagc tgattaaggt aagtaagaaa ctaccaaaag ccagcatgag ttgaagggcc
     8161 tcgtaagtag acaataaaac gctcctttct gttggatttt gatgcattgc ccataggtat
     8221 caccaccttt cagaaatcag agccaccgcc ttagcttttc tgtaaagaac attattatat
     8281 cataatcaca caagaatccg tcaaatctta aactaatcag gcggcttttt tatgctctga
     8341 ctataggtct gaagagaaga tgctagatgt cttaggtggc tttccattta aactacgagg
     8401 tcttctttct cacagagtat agccccctct tttttcagct actgtttcgg aggcaagctg
     8461 gcatttcgtc taaattgctt ttgtttttcc ctgagcattc gaaaaaatcc tttatttcta
     8521 cctgacatat cactaaaaga gggtcctgtg accctctttt atagctatct gttagagaga
     8581 tatgcaattg ttagtcttgt tttttcttca agcctaggac acctgcgcta gcaatgacgc
     8641 tgagagctgc aagggtgaaa aatgggtgat ttgcctcccc cgtagctggt agcgtgccct
     8701 tttgagctgc tggagccgct gatttgtttg gtgctgactg aggagctggt gcctttggac
     8761 tagctggctg ctctgaagat tttggtgcct gtggagcagg ggattgctcc ggtgcctttg
     8821 gagtctctgg ttcttttggt gcttgtggtt gctctttttt ctccggtgtt tctggagcct
     8881 ttggcacttc tggcaccttt tgtgattccc cttgttgacc tggcactcct tgtggcccag
     8941 tatcaccttt tggaccttgt tgacctggtg cgccttgtgg gccggtgtcg ccttttggtc
     9001 cttgttgacc tggtgcgcct tgtgggccgg tatcaccctt tggtccttga agtccctgtt
     9061 cgccttgtgg cccagtgtcg ccttttggtc ctggttgacc tggctctcct tgcgggccag
     9121 tatcaccttt tggcccttgt tgacctggtg caccttgtgg gccggtatca ccctttggtc
     9181 cttgaagtcc ctgttcgcct tgtggcccag tatcaccttt tggcccttgt tggcctggcg
     9241 ctccttgagg accggtgtcg ccttttggtc ctgggagacc tggttcacct tgtgggccga
     9301 tgtcaccctt tggaccttgt tgacctggct ctccttgtgg cccagtatca ccttttggcc
     9361 cttgttggcc tggttttcct tctggtccct gtgggcctat tggtccacgc tcaccaactg
     9421 gtccgcgttc ccctcgaagg ccttgaggtc ctgcgggacc cattggacct tgaggtcctg
     9481 gtatccctaa tgaatctttc tcatacaatt tgtataattg ctctgattgg cctgtcgatt
     9541 tttttaaaaa ttgctccact cgccatagat atcttaaaac attttctagc attcgaccat
     9601 tgttataatg tgtcgaagtt tcccagtcac ttgagctacc agaaccagga ttaagtattt
     9661 ctttttttat gaactgttga aagaaatatc cttgattata catagaagga tatgtaaagt
     9721 cttctgccct tacatcattt ccaatcccta agctagctat ggttgctagg gcgacaactg
     9781 ctgagcagat accgtacttc tgaacaagcc tgatacttgt tttcttgttt ctcatgttta
     9841 tctcctttta gtttagaaat gttaacgatt tctaatcttt tttcttccaa agaaaatctt
     9901 aacatgacgc ttgcgggctg tgaatatgtt ttggggaatt cgcttccgta gtttcgtttt
     9961 tttctaatca aagggtcaat tgtctgacgc tagtgtcttt tggcattggc ctttagctta
    10021 ggaagactgc ctatgttagc aagcttttca ttagcttatc cgttttgata aagggtaagc
    10081 gacgaggata atctgacttt gtcttttgct tttgttagat tttttaatgt ttttttgatg
    10141 tctgatgact tttaaaaaaa gccttctttt gataggcaag cttaaaaggc ctaggcaaaa
    10201 gcccagaccc ttgctgctat tatctgttat tgtggaaagc taccgctctt tggcactgtc
    10261 atgcttaaaa attgcgactt gagctattgt aaccatagcg ctcaaggaaa tcctgacgaa
    10321 actctaaaag gttatcgtcc aagatagctt gacgcacctg cttcatgagg tttactaaga
    10381 agtataggtt atggtaactg gtcaagcgca tgccaaaggt ctcatcagcc tttaagagat
    10441 gacgcaggta agcacgtgtg taatgctgac aggtgtagca gtcacaatga tggtcaagtg
    10501 gggtaaagtc ctctgcaaac ttagcatttt tcacaacgag acggccctcg ctggtcatgc
    10561 aggtgccatt gcgagcgata cgggttggca ggacgcagtc aaacatgtca accccacgaa
    10621 tcaccccatc aatcaggcta tcaggtgcac ctacccccat caggtagcgt ggcttatttt
    10681 caggtaaaag tggcgttgta aaatcaagga cagcattcat ctcagcatgg ctctcaccaa
    10741 ctgccaagcc accgatagaa tagcccggaa aatccatgct cacaaggtcc gcagcagatt
    10801 gacgacgcag gtcctcaaag ccagctccct gcacgatacc aaagaggcct tgatcatgag
    10861 gacggcggtg agccttcaag ccacgctctg cccaacgact ggtgcgctca atggattttt
    10921 tcacataatc atagggctgg taaaattgcg ggcactcatc aaagctcatc ataatgtcag
    10981 accctaggtt attttgaatg gagatcgctt tctctggtga taaaaacatc tttgagccat
    11041 tcaggtgatt tttaaaggtc accccctcct cagtgatgtt tctggagtct gccaaggaat
    11101 aaacctgaaa gccgcctgag tctgtcagaa ttgcctgatc ccagttcata aatttgtgaa
    11161 ggccgcctgc acgcgcaatc agctcatctc ctggtcgtag ccataggtga taggtatttg
    11221 acaaaataat gcctgaccca atctccttga gctcctcagg agactgtgtc ttaaccgtcg
    11281 cctgtgtccc taccggcata aacatgggcg tcggaaaggt cccatgcggg gtaataatct
    11341 caccgagacg agcacctgta tgcttttcct ttttgatcaa acgataagta atagggtaat
    11401 tagtcattgt ttcttttttc cttgctatca agataaacag tcttgagcgt tttgcatacc
    11461 acttacaaag cacttagtca agcggtatgg gcttgtttag agccctatca ttttatcaaa
    11521 aaatctctga cttgtcatgc cttcaaagag acaagatccc gaagcaatgg cacgacagac
    11581 gcatgaagga gttttagcaa gaaaagaaag ctttctgtcg ttcaatgttc agctatttca
    11641 agtatatgtc ttatctttta taaactttac tacagaaaaa tcgttgaaaa tgtttgcttt
    11701 actctatact atcattcaga aatagctgtt tcgcgcgttt gtcgtgagca aggacggtat
    11761 gggtatcact ggctcctaga atatggtata atgtaccaaa ggagttgtac gatgtcaatt
    11821 agagaaataa aacgtgaagc tagacagact ttaaagggac taaaggggaa atacctctta
    11881 tttttagtac cgataatctt atctattttt tactcaggaa ttgaggttca tcagacctat
    11941 gtgaccactc aggggattga ggtatcagtc ggggcaagct actttccttt gattgttctg
    12001 ataatgctga cggtctttac cttatcagca gcctatacca tgctagatgt tatccgctac
    12061 tatcgtcgtg aggtctcttt ttcagaggca acgatagctt tttctggaaa cttgtttggc
    12121 aaggtccttg ttttgttgat catcaaaggg ctcctattta tcctatggtc tttgatttgg
    12181 attgttggct tggttattct aacgattagc tctgcggcat tactgacaag ctacaatact
    12241 ggtgctgctg tgatgactcc aatcatcttt atggttattg gttttgtgat ttttattatc
    12301 gggcttattg tttatatgaa tcgttattgt gcttacagca tggctgagta cattctctat
    12361 gacaaggtca aggaaggcac ctatatgggt gctattacgg caatcgaaga gagcaaggac
    12421 atgatctcag gctataaagg aaagtatttt ttactacacc ttagctttat tggctggttt
    12481 atcctagtaa tcttgtcttt tggcttgatc tatatctacg tactgcctta ttacaccact
    12541 gctgatgtga ccttttacca ccatttaaag cacattcacg atgaaacaga gctgccgata
    12601 gatgctgaaa ggcttactat cacaggttca aaagaagccc catctgctat tagctagcct
    12661 taacgatatg cctctatgtc tctcatgacc ttgttcagag tagacataga ggttttttgc
    12721 atgacctttg ataacttttt tatagtaaaa aagaggagcc catcagttgc ctatccaaag
    12781 ctagatgaca catctaacgg ttggaaggct tgcttacagg ccctctttta gcaatgttag
    12841 cccaagacta tcctaaagct gctgaaaagc tcctcggtct aaggcatagg cagtcgtcca
    12901 atggctctca cgatagtaaa taaagagctg gctatctaat agctcatcaa ttgaggctgc
    12961 tgttggcaga cctgctaggt caatgaaata atcccctgga agaagctgtt gtagcttttc
    13021 cattaaggcg gtattaacag cggtctttgc tgctggtaat tgactagaga ttgataagcc
    13081 ttcaaaggtc tttaaatcta tgttttctga ctctaaagct gattttaagg ctgatttgat
    13141 caagtctagg ctgtattcag catctaaggc ttcatcgcct gatgagaggc tattcatcgc
    13201 caatacatac aaagggcctg ctgccttatc ctgataggta atgacaagtt gatggttcag
    13261 caaatcagct aagtcatcat aagtaccagt gttctcaaga gtaatgtaat aagtccctgt
    13321 gagccctaag tccttgattg tctctaaaat cttgccttgg attgcttgat ttttttcagt
    13381 tgttgccgct gttagaccac tatttgtaat agcaaagctc tcaatctctt tggtagctgt
    13441 attggtctct tttagaatgg ttagaatact atctttaagc gctagaatat catttctaac
    13501 cggtgcttca atagggctag agatgtcttc aaagaaacga taagcagaac cgctgacaaa
    13561 tttattggcc tgtccgctgc tttttccata ggtgtctaag gcagttattc taacaaatcg
    13621 acctgttgtt ggtgtaaagc tgactgtttt tagctcagta ttttgcttcc aatcagtgct
    13681 atcgacaacc gttgtccaga ccttaccgtc tgagctgatg tcgacctttg cagaatggat
    13741 cataccatta acacctcctg ggagataggc aatagcagag aagtttttat cgtccttaaa
    13801 ctcaacagta tatgacttgt cctcagtaac ctgattaaat aaggtatgcc attgggtggc
    13861 catatctcta ccatctacca tatgcttgcc agacctgcct gattgctcat tagcataggt
    13921 caccgcctga atatcatcaa ttgagatgta gtgcattgta ggatcagtgc tgtctgcggt
    13981 aaaggtatag gtaacgctgt cacttgctag actggtgcca tgagcccgat agcgagcaag
    14041 aactgtgaca gtgtcattga agcgctctgt gccatcataa gcctgccaag actggccatt
    14101 atccagactg acctccaaat gttcaatagc accaatcaag cgattttcca agtcattgcc
    14161 ataaaggctg ctgttggtcg gtgctgctgc ctttgtcagg ttaatcctgt aggtagcaga
    14221 taccgcgtca aagccaacta aaataccgtc ctctatatta agcttggcca aaaggtcatc
    14281 actaaaaacg ataaccttgt ccttggtttc aagccatgtt ttcccattat caatagaata
    14341 gcggactgtc aaatctgtat cctgataatt ctcatgcaaa cgaagggtct tgtcatcaaa
    14401 gctaaagctt gctgtttcga ttggattgcc cgttaggata tagttggcga taattctaac
    14461 ctcattagat tggagcactt ccttatcagt tgctgttttg gctgcgatta gagcgttata
    14521 gctcagtaaa tctagctcag ccttagctgc ttgatcgctg atattaggcg tgatacgctt
    14581 gatagcctct accatgacct gtggatagta ggtgtaagct gcaatgacac gctttcctaa
    14641 gtccagccaa tcctgatctg ttttttggcc attttttgca taggcctcta tcaagccatc
    14701 gtaagtatct agattaagct ctagtacatc taaagccttg ctgtaggcct caatctgttg
    14761 atcactgcca gcctcgtaga cattagcgat gagattataa taaagcgatt ccttgaactt
    14821 atcgtattgg tttaaggctg cttgcgccag cagcatatag ctagcgtttt tatgaatgtc
    14881 attgtaggat tttaggcccc agccaagcaa gagcctagcc tctgttgctg ttgtggttcc
    14941 ccaacgagaa taagagattg cccagcgatt accataaaca ttgtctctaa tatcccaaat
    15001 cccgttgccc tgatcatctt gacggtaaac caaataagcc tcgtggtcat tttggtaaat
    15061 attgaccgct ggaataccaa agacctcatt gactgctaca cctaaatttg ataatcccca
    15121 gcaaacagcc cctttttcca tcagcatcca gatccggtga cggttgtcat aagtaacatt
    15181 aaaggcatcg tcattgaggg tgccaacgag ctgatatttt tctgtccatt gagcttgatt
    15241 gtcagcgctg cgcatgtctg cgccaccgta gccgatgttt ttgtatttcg tataagagta
    15301 gccactggta tagctagcaa ccttatctcc atatttttgt tcggcgtaat gatgcagcca
    15361 gagaatttcc tcatcatcta ttttggcgtc cataacagca cgcaccaact ccatattgta
    15421 gttggcgaat tcttctttcc tcaagaattc gttgtctcga tacaattctt taaaggcttg
    15481 atatttcagc accgggtcag aagcaaggta ggtgccacca tagttaacca caaaggattt
    15541 gatctccttg cagtaggcaa cagcagttgc cagcatcatt tttttgtaga catagccatt
    15601 tcccttgtcc tccaaatctg ccttattagt agcataaagg tctcctaagg cgttcaaggt
    15661 ttttagggta gagccgttaa acatcgagcc tgcctctaaa aacagtgaca gagcgtcctc
    15721 atctgacaat agccaatcaa gagcgacctt gaccttttca tttttcttga cagcagattg
    15781 aatggtgtgg tagccgacac gattgacaaa ttcgcgctca agcactaatg ccaaattgtc
    15841 tggattatca taattatctg tgacactatt cttgctgaga agggcatcat actcttcagt
    15901 tgtctttagc ctgtcataag acacctcgct tgataaatca taatctgtct tgagcaacct
    15961 gagatccgca taaacagagt gatcattacc gttatttttt agtgaatttg caattagctt
    16021 tacatattta gcacctgtaa tatctagatc aacataaaca gcctcactgg ttccggttac
    16081 tgtaccagtt gtcaccaggc tttcccaact ttttccgtcc ttagacttat agatgttaaa
    16141 gctaacacca tcgtccttac cacgtctact atagtcaact cctaggtagg ctgatagacg
    16201 cgtgtattca ttggagtatt gttcaacatc ataataaagc tgtgaaggag catgcactgc
    16261 aattccctta tcaaatgcaa gcacctcgcc atcaactact agagtaatgg tgccaccggc
    16321 agggtttttg tcctgtaaaa agctgccatg cccaaccttg gacgggttga cacgtgtctc
    16381 atctgataag tagatatagt ccttagcttc agtcttattg gtggtctcta ctgcttgtga
    16441 tacttctgtc tgctcctgct ttgtggtctc ttcggcagaa gcttcggtag cttgctctgc
    16501 tgcggctact tgactcttag agtcagttgt ttctgtagtg gcagtaccta ttactactgg
    16561 cagcgtttct gaggagccct cagctgctgt gtcttgcgca gcggttgctg attggtcagc
    16621 tgcttgttga tcaaccgctt cttgtgcttc taacgtggtt gctatggctg cactagctgt
    16681 tacttgctgc tcatcagcag aaacagttgt cagccctagt gttaaaaata aggttgcaac
    16741 caacacagag gctgcacctg ttttaaaggt tttaatggca aagcgctgct taccatcagt
    16801 ataaggtttg aacatggtgt cttctccttt aaaaataaga tatttaagca aaataaagac
    16861 tgaccaccaa ccactacagt tgataatcag tccaacaaag atatcgtact ataggaaatt
    16921 aattaaaggg ggaaaatcat cgcctacagt taatttgatt ctttgcgtct tgacacaata
    16981 gcaagctggc ctgcacaagc aataactgca agagctgctg ctgtaaagaa tggattagct
    17041 gtatcagcag ttgccggaag cacttgctgc ttatcagctg ctttcttgtc ctccttctta
    17101 gcttcaggct tagattctgg tttaggctct ggcttaacct caggatctga tggttttact
    17161 ggatccgctg ggtcgattgg atcgaccggg tctaccggat ccactgggtc taccggatcc
    17221 actgggtcta ctgggtctac tgggtctact ggatccactg ggtctaccgg atccactggg
    17281 tctaccggat ctactgggtc taccggatcc actgggtcta ctggatctac tggatcgacc
    17341 ggtttagcaa ccaaggctgc cttggcatct gagagggatt tcttagcatt taacacctta
    17401 accaagctgt tagtaatagc tgtcggttct gtctcctgag cataagctgt ctcacccgct
    17461 gctgcgacct ccttagcctt agctagctgg tctgtatagg cttgagcaga agctgctgta
    17521 tatggagata ggtctagatt ttctccgata agagcattta attggtctaa agcagaacgc
    17581 aattttgcct ttccttcttc ggcaatcgca gcctttacct ttaaaatagt atcaacaact
    17641 gaatttgttt ctgtagtgta gcgctctagc tcataaaggg aaatgtcttt tctctcttta
    17701 tccttgttaa cagttctata gaaggtacct gctgcttcaa tggccttatt gtacaattcc
    17761 ttcaaagact ctgatgtcaa agcaagattt ggattttctc ggtaaagctc taacagctta
    17821 gccaaggctt gatctaaggc ttcatgcgct acagcagtct taagcgtcgt aagagcttgc
    17881 gttaaatcag tcgcagcctt atcaacatct ccttgtgaag gaccaaatga attttgaagc
    17941 ttagctgccg ctgcaagctt ttgcacaaga ccgtcatacg cttctttagg atactctttg
    18001 ccatctgtta taaaaggtgt agcttgatta atagcttcat ttaaagcatt aagattaaca
    18061 agactagtaa tagcggaatc aatagtagta acagattgat ctactgtatt ttgatcaggg
    18121 tcactgttta aataggtctt accaatagta accgctgatt gcaaggcttg cagtgattca
    18181 tcagaatacg ttccttcagg ctggctgagt tttagcttag cctcctctaa cgacttcctt
    18241 aactcagttt tattgctgtt ggaatttttt agtttaaatg tgaagagctt tttggtatca
    18301 tttttcccat agaataccca agctttaata gtataagatc cccccggtac agcatatgta
    18361 ggcgaagcta acatttcatc agttaaaaag gaagtacccg cagcattgta aaagtcaaac
    18421 catattttta ctccaggggt atcaattcct cttgaaccat ctccattcga aataaagtca
    18481 aaagtatctc catcattaac agtcccatta ctacctttac gagtaaccgt aatttgactc
    18541 ataagatctg agatagtaat tggttctcct aattcaactg tatattcttg tggaatatct
    18601 atgtgccagt tcagatgttg acctgtccca ttattttcaa atgcactagc agtagtcgtt
    18661 tccgccccta ctgttaaagc gctatcaata ttatccgaca aggcaaccaa tcctgtgctg
    18721 aaaactaatc caacaagacc acagccctta agacaccgtt tcgtgaattt cttcattctt
    18781 ctttttcctt ttctagagcc ctagcaggct cgaacaatag caatatgtgt catagggcag
    18841 ctgctatcac tagtagctgc cactttgata ttagcctgat tgtgacactc aaatatcact
    18901 tataatttac aaaaaatttt aagaaaagtc aatatacaaa cggtttttgt taaatttttt
    18961 aaaaatataa caaaaaacaa gcacgccaat ctggtctata acagttttta ttgtcaatag
    19021 tgatcgctaa agggtttttc agccaacaaa aaaagagtga gtccctaact ctctcttcta
    19081 gactttgtgc catatcatca gctacacgaa cagccaagat caaaaaggcc agctctcaat
    19141 agtctgtgtc cttaccctgc ttcgtctgac agctagggca aacaccatag gctataactg
    19201 gaatacgggt gaccttatag cctgtttgct ggtgtgcttc cttagcgata tccatcacat
    19261 ctacgtccat aaaatcagcg attgtcccgc aaacctcaca aaccacattg acatgctgat
    19321 gtcccataaa gtcataatag gtcgtcaaat cattactaat tttcagctcg gatacaaagc
    19381 cctcatcaac gagaaccttc aaattattat acaccgtagc aaggctcata ttagggtatt
    19441 gaggctgtaa atcacgatag attttatctg cgctggggtg ctcagtggac tgaatcatgt
    19501 aagaaatgat cgccttacgc gtctcggtaa tacgaatatg cttgtcacgt agatgctcta
    19561 ggacattttc ataggcattt agagcttgct gatgtgaatg aatgtccaag cttacaacct
    19621 cctccttttg taactatggc actaactagc aggaatcttg atcctgcttg ctgattagcc
    19681 gtaaatagtc aatcttgata cagcgattca taacaatgtc agctttgcct gctgatcgca
    19741 aaagctcctc agcttcttgg ctatacaagc caagctgtgc ccaaaagacc tgaccctgac
    19801 aagctaaaaa gtcctgagca acctgaggca aatactcact tcgtcgaaag acattggcaa
    19861 tatctacctt aaaaggaata gccgcaaggc tagcataaac gacctctcct aaaacagact
    19921 gacctgccag cctaggattg acagggacaa tccgatagcc cttagcctgc ataaacctag
    19981 ccacatcata agcagcagtg gtttgacgat cagataagcc aaccactgca atggtcttgg
    20041 aagattcaag ataagaggtg atagtctcat cagagggatt ttgaaatgta tcaatcatca
    20101 tttacttcct ttttatcaag cacacccaat agcaaatcaa caacaggaaa agacaatcgc
    20161 tgccggtatg acatagccaa ccatctggct accaagctca aggaaaaccc tccttagcat
    20221 gacatgccct gctgtttttt tctcttcatt atagcataag tttttaaaat gcggaacaca
    20281 aggaataaca gcagccacac caagcaggct gccacttaac accactgcta atctagtcta
    20341 cttggcctca taccagctct tgccggcact ttcgtctaca cgcagcggaa ctgccaggct
    20401 gacagctgat tccatcgttt ctttgaccag cgctttaaca gccgctagct catgattagg
    20461 cacctcaagc acaatctcat catgcacctg aagcagcatt ttggtctcaa agccaccagc
    20521 tactagggct tggtcaagat ttatcatcgc aattttgaga atatcggctg cactgccttg
    20581 aatgggcgaa ttaatggctg tacgctctgc aaaggagcga acgttgaact gacgagaatt
    20641 gatatctggc aattgacgac ggcgcttaaa gagcgtctca acatagccct tatccttggc
    20701 ttcacgcaca accctttcca tgtaagcctt gataccaggg tagcgctcaa agtaggtgtc
    20761 aatataagcc ttggcctgtt ttcttggaat tccaaggtta ttagacaagc caaagtcaga
    20821 aatcccatac acaatgccaa agttaacagc cttagcattc cgacgatcat tggcagtgac
    20881 gtcctctggc ttttcaatgc caaagacacg cattgccgtt gaggtatgga tatccgctcc
    20941 ctccttaaaa gcagcaatca aatgctcatc tcctgaaata tgtgctaaaa cacgcaattc
    21001 aatttgcgaa taatccgagc taagcaaaac agcatcatca tgagatggag taaaggcctt
    21061 acgaatcaag cgcccctgct ccagacgaat cgggatattt tgcaggttag gatcaacact
    21121 ggaaagtcgg cctgtctggg ttaaatcctg taaatagcgg gtgtggatcc tgccatcagc
    21181 catgatgtaa tcctgcagtc caatcacata ggttgattgc agcttagtaa tttgacgata
    21241 gtccaagatc ttagccacga ttggcgcaat tggcgctaag cgctccaaga catcaacagc
    21301 cgttgaatag cctgtcttgg ttttctttgt caaatgaaga gggagctgca ttttctcaaa
    21361 gagtatcact cctagctgct tgggagaatt aatattaaag acctcaccag ccatttcata
    21421 gatttcctgt gtcagttcct caatgaccac cttattttgc tctgccattt cctgcaggct
    21481 atcttgattg acagcaatgc cttcgatttc cattttcgca aggacattgg caagcggcag
    21541 ttcaatgtca gtgtagagat cagcctgctc atgctctgcc agcttatcaa gcatgactgg
    21601 tctactatcc agcaagacct gaaccttacg cgccagatgt cctaacaaaa cagccttgtc
    21661 aggcacagca cgcttgaccc ccttaccata gacaacctca tctgtatcca gtgatatagt
    21721 ggtataaaga cgtgccagag tagccatctc attgtcctct acagttgaca agaggtaatt
    21781 agctaagcgg gcatcatagc tggcagccgg caaatcaagc cccagatgac taagcagaac
    21841 cttactgcgc ttaaaatcat aggtagcaat cggctgctca agaacctttt taaagagctt
    21901 tgtagtgagg agactaatat ctgctgaagc ataaatctgg ccttggttgc cccaagcaaa
    21961 gccaatcagc tcctcgcggt gataattatc cctcaaagct tcaaaataaa acaccgtatc
    22021 gtctgaaaac atgtccgctc ttatgtcagt aacttcctga taagcaatct cagctaccgg
    22081 ctcctgtggc aactgactag ctaaggcatt ttttagttga acaaaatcca tctcatcata
    22141 aaattgtgac aagcgatcta gatctggacc ctgatagaca atatcctcca atccaatcgt
    22201 aatcggagcg ctagtgttga tagtagcaag tgtctttgag aggaaggcct gctccttatc
    22261 atgaagcagg ttttccttca tttttgaagg cttgaagcta tcaatatgct cgtaaatccc
    22321 ctccaagctt ccatattcgt gcaggagctt tagacctgtt ttttccccaa ttttggtcac
    22381 tcctggaata ttatcagact tgtctcccat gagcgctttc aagtcaatga attgctctgg
    22441 cgtaagcccc attttgtcca taaggtaggc tggggtaaac tcttcaaatt cagcaactcc
    22501 ttttttagaa atctcaacaa cggtatttgc atctgtcagc tgaatcaaat ccttgtcacc
    22561 actgacaata gtcacatcaa aaggaatctc tgtacgctct gccattttat caagcgttcc
    22621 gataatatcg tctgcctcgt aatgctctag ctcataaaag gcaataccaa gcgctcccag
    22681 catatcacga atataaggaa actgctcccg aaattcatca ggggtcttgg cacgtcctgc
    22741 cttgtaatca gcaaaaagct ctgtccgaaa ggttgtttta cccgcgtcaa aggccaccaa
    22801 gacatgcgtc ggctgaacac gcttcatcat gtggtctagc atcaaatgaa agccataaat
    22861 cgcattagtg tgaagaccgc tgtgattttt aaagcggtca atctggttat agagggcaaa
    22921 aaaggcacga aaggccactg aggagccatc aatcaaaagt aatttattct tgttttccat
    22981 gcctttatta taccacacag tgacctgctt tgctctgacc agctacgctt tttgcaagca
    23041 ctagcaggta aagcagcata cccgtagctt gatcaaaaga tccaagctgc ttgaaggaag
    23101 ataaatgact gcttttgctt tatcatcaag acatttctac caaaaaagag actgagataa
    23161 aaagagtgac actttagaga gtcttaacta atatcctttg ttatctaatt cattaacaaa
    23221 cgaacaggcc tagttttcaa aacctcagaa aactaaacct gttcatttgt tctatttgaa
    23281 gtcagacttt gtctcaatct ccaaattgat gacatcatct gctatgactt tcctaagctg
    23341 atatggacgg aaagccttct gcaaaatcca tgattagtct aggctacatt tgagcgagcg
    23401 gccttatgac tgagtccatt tggccacctt atcagcatgg ctagccaccc atttcttggc
    23461 tgcggcttct ggtgtcatgc cctgattgat gtcaagcata acagcctcca tatcctcttt
    23521 ttcccaatgg aagtgatcaa caatcctatg aacagctggc aggtcggcct ttaagccccg
    23581 acgtgcaatg gtattgatat tttcctttga gccaaaggtt ttctttggat ctgccaggta
    23641 tttcaaatcg tacttagcaa acatccaatg aggagaccaa gccgtcacaa cgatcggctc
    23701 ctttttcttg accgcctgat caagtgaggt ggtcatagca cctgtcgaag cagcaacgag
    23761 ctcccaatct gccaagttgg aataggcctt ttgcgtctta tcagcagcag tcataatacc
    23821 agctcccggt tcaatcccaa taatctgttg attggcttga tccgaaagct cctctatgct
    23881 gttcacatcg ctcatatagg ctggcacagc gagtcctagc tttgttccct tcagattagg
    23941 accaagatta tccagcttat cctgatactt ttggtactgc tgctgatggg tcactggtaa
    24001 ccaggcactt gttgaaaagt ctgcatcgcc atttgcgatg gtttgccaca tcacagcatt
    24061 atccagtggt gtcaaggtta cctgataacc ctcatctctt aagacctgag cgataacatg
    24121 ggtagaagcc acctcagaat cccactgcac ataagcaatg gtcaccttct gccccttgtc
    24181 tgctgagctt gataacatcg cagcaaagcc acgccccaaa gctgacaaca aaaagacagc
    24241 taaagcagct agaccaagcc atttcttggt ttttccagtc tgcgttcttt cttgcggctt
    24301 accgttaaaa tgctgagtca tacgatccaa aataatcgcc aagataacaa gggccaaacc
    24361 actaacaaag ccacgcccaa tatcagcatg ctgcaaggcc gataggacct cacgtccaag
    24421 acctggagca ccaatcattg agcctgtcac aaccattgat agggccaaca tcatggtctg
    24481 attaacacct gccatcatcg tatgctttgc caagggtaat tcgaccttca gtaatttttg
    24541 tttaggggtt gacccaaagg catctgaagc ttcaaccaat tctgtcggaa tatgacgaag
    24601 cgctaaattg gtaaaacgaa cagtcggcgg caaggcaaag ataaccgacg caaagacgcc
    24661 agggaccata ccaatgccaa aaaaggcgac agccggaatc aaataaacaa aggctggcat
    24721 ggtctgcata aggtccagca ttggattaat cacctggtga acaatcttat gtttagccat
    24781 ccaaatgccc aagggaatac caagcaagac agagatgagg cttgctacca aaaccagcgt
    24841 aaaggtattg atcagctctg cccacaggcc ttggttatag acaaataaca ggcccaggag
    24901 ggtaaagatc ggcaaaggcc atttttttct tgccaagaaa aacatcgcac aggtaaccaa
    24961 tagcataaac agtaacggat tgataaacaa aagggtctgc gtgatccaat ccatcaaagc
    25021 attgcccaca agctgcagca gatcaaagaa gcctgaaaag gtttttgtca gccactcagt
    25081 tagttgctca accagctgtg ccactggtag agttgtttgt aataggtttt ccaaaataca
    25141 gtctctccat tctaattaag gtcgtcatct ggaatattag ccaaggcttc aaggacacgc
    25201 ccacgaataa taacccctaa caagcggtgc tgctcatctg tcactgcaat tggcgcagaa
    25261 gagtcataaa tcaagggcaa aatatccgta ataacagtat cctttgagac cgttctgaca
    25321 ttacgatcaa taacctctga caaggggagc tttttctgac gtgcttcaat cgctccgtct
    25381 gctgttaggc ttcctattag ctgacgacga cgattggttg ccatgagcat agacacctcc
    25441 tcattgtgca tacgattcaa agccacctgc ggaccgtcca gatcaaccgt tgttgtgata
    25501 ggcttaatca taatatgctg agcagtcagc acctttgagc ggtcaacgtc ctctacaaat
    25561 tcacgaacaa aatcattagc cggattggtt agaatatcct cacccgtccc aatctgcatg
    25621 atctgaccgt ccttcatcaa ggcaatacga tcaccaatac gcagagcctc attcaagtcg
    25681 tgactgataa aaataatggt ctgcttcatc gtctcctgta attctagcag ctcatcttgc
    25741 atgtcacgac gaatcaaggg atctaaggca gaaaaagcct cgtccatcag caaaatctta
    25801 gggctgtttg ccaaggcacg cgccaagcca acacgctgct gcatgccacc agacaattga
    25861 tcagggtatt ggtccctgac ctcaagaagc cctgactgat caagcgcacg ctttgcaatc
    25921 tctcgacgct cctgctttgg taccccacgc agctccaagc caaactctgt gttttccaaa
    25981 atcgtcttgt gtggaaaaag agcaaagctt tgaaaaacca tattcatatc atgcctgcga
    26041 acttctctga gctgatccac agacagttta gaaatatccc ttccctctaa taaaatagag
    26101 cctgctgagg gctcaattaa tcgattaagc atacgaacaa gcgttgattt gccgctgcct
    26161 gaaaggccca tgatcacaaa aatctcgcct tcctgaacct caaagctggc atcatagacc
    26221 ccgacagtaa ctcctgtctt tttaaaaata gcgctcttac ttttaccagc cttgatcatt
    26281 tcaagagctg ctttttgttt tttgccaaac aatttactca aatgcctgac ctctaaaata
    26341 gttcccattc ttttcctctc ttgttctctt cctcgattaa agctaaatta gcttaataga
    26401 tttctaaaag tgccaccaca attttaaaat aatgaggtca ctttttgctt aaaaaaaaga
    26461 gtctgcctaa acagaacaca ttaattatat aatatatggt cactttttgt caagctggac
    26521 gcttgctacc caagtatcag gatcgtccta agcagtgata tcactagtca accaagcact
    26581 taacagccct gaacagacca cagcaagcag gcctttctga cacttagcgc cttgagagct
    26641 tacccagcag cctcctctag ctgacttgat tgacctatct gactcttgtc ctgcaaccaa
    26701 accaatgctt agactgccaa gcaagctccc aatagcaata agatctgcta agcaaagcgt
    26761 tagcttgctt tgaccatagc tgctagtcat gtctaatagc actctagata aatcaaaagc
    26821 cccacctagc aaggctagat gaggcaaaat aggtttagag aagggcttta aactgaatat
    26881 ttgagtcttc caagaagcag tcgtcaaagc cacgtgggtg atgatactcg atgcgatcct
    26941 gatcctgtgg ataggtgtat ttgccaccaa cctcccaaat gaatggatgg aattggtatt
    27001 gcaagcgctc cttacgcatc ttccaaagct ctaggatttc atcagttgag gccatgaagt
    27061 ttgaccagat atcatagtga accggaatga caaccttggc gcggagattt tctgccatac
    27121 gaagtaggtc aacagaggtc atcttatcct gaataccgat tggattttca ccataattgt
    27181 tcaagacaac atcaatatcg tagtcacgtc catgcttagc aaaatagttt gagaagtggg
    27241 agtctgcacc atgatagatg gttcctcctg gtgtttcaaa aatgtagtta acggttttgc
    27301 gagctaactc ttcgtcagtc actggaagtc ctgctagctc gccaccattt tcctcagcgc
    27361 cagcaactgg taaggtaacg atacaggtac ggtcaaagga ttcaacagca gtaaccttga
    27421 tatccttgaa tgcaaagcta tcgcctggtt ttaccacgat gatacgatcc tttggaacac
    27481 cccagctctc ccaaatcttg ccgcactcat aagggccaac aaatttgaca tggtcaagct
    27541 ttggattgtt gataatggct gctgcagtat tgatatcaat gtggtcacta tgataatgag
    27601 acaccaagta atagtctaac tcattaatca taaagggatc aataaccatt ggctgagctc
    27661 ttagatttgg ttgtagcttg cgaacccctg ccatattggc catttggtga ccacgaacca
    27721 tgtcttttac ttttttagtt gcctttccac gattggacca taggtccatg acaacattgg
    27781 caccacccgg tgttttgatc cagataccgc agttacctag ccaccacata gagaaatttc
    27841 cttcaggcac tacctcttct tcaatttctt cgtttagcca ggttccccat tctgggaagg
    27901 tgctaagaat ccatgattca cgagttatat cttgtacttt agccattatg tttcctccaa
    27961 aatgaatttt tatctatact ctaagtatag accttcttta ttctcataaa aagaccaagt
    28021 gtcacacact cttgtgttca aaactggact gaattttggc tcaaaataaa ctaaaagccc
    28081 cagccttctc ctaaaccaat agacagctga ggggtcctta tcaataggca agctagtagc
    28141 ttacaataat tcgtgatgaa tgagcttttc aatttttgtt ttcaaggcat agcggtcagc
    28201 atcgtcctta acaatggtct cgatcgcctt ttctagctca agggaaaaac gagagctatc
    28261 actcaagcgc ccctgctttg aaaaacggat caatctaata atgtcatcat cgctcaaaat
    28321 aggattgaca atcagtacgg gaacaagagc ctccagtgcg tctgttgttg ataccacaat
    28381 gtcaacagac atcaaatcaa agacactctg gtattgctct gttgtaaaga cagcctcgat
    28441 ttgacaattg ggcaaataac gctggcactg cttcaacagc agcttttgaa tcccaatgcc
    28501 atcatctgaa acgataacaa gcttggtctt gtcccagtca gcatgactat ggcgcagctc
    28561 tcctcccaga tgaatcgtta gataagccac gtcatcatct gttagacgga tctgccaagc
    28621 ctgctctagg attacagcac aggattgagc catagcaaag agctcctcgt atttttcctt
    28681 aatatggtct gttaaaggat tgatcgaaaa aatcccatag gcctttcgat aaacaagggc
    28741 cttgcaatgc ctggtcagct gtctaagcaa gtcctttttg tgggtaaaat gcagctgata
    28801 gcgcagctcc agctgatcga taaaatcacc aatagtggct cgcatctgct cataatcctg
    28861 actttcaaca tggtgatcct gatcttttct aaaggatagc atcagcatgg ctatcatgcc
    28921 tacctcaatg tcatctaaat gcagcttgaa attgtggtaa agctcactag ccaatgcctt
    28981 agcaatctgg tattccttgc gcttccaaat caggttaaaa tcccttttaa gcgctgtttt
    29041 agtttccgaa tgcaattgca tgttgcgata gctaagcagg ataaaaggaa gaatttgcag
    29101 cataaactga ctatcctgaa tattaattgt tttgcctagg ctagcctgag acaaaaagag
    29161 gtattcgtga aaataatcca aaacctcctt tgaaaaataa gctgacaagc cttgtgtctc
    29221 agaaagctta tgatcaaaaa gctcaataaa gctgctattg cctccctgat aaacacctgc
    29281 caataccttg taaaggtact gaatcaaagc catagggtga cagtcaaagt aatagccctt
    29341 ggccttggtg gcatgcagct gaatcttatt gttatagcta gacaattcct ctctcagttc
    29401 agcaaggtca tttaagatgg tatttctgga aacatcatta atcatcatga gcttatccag
    29461 tgtcacccgc tctgttgcca ctgcaatata aatcgctgat aagctcctgc gctcatcacc
    29521 cttcatgaca tagtgataat ctgccacttc attgaggagc tgttggcagg cagccttttg
    29581 ctcactattt agcaagatgc caacccgagg ataggagaca atttgagcaa catggctggg
    29641 cagcgcttcg ttaattttat ccaaatgata atagattttg cgccgcgact gacccaaggc
    29701 agctgaaatc gccatgactg tctcagcctc cttcaatcga atcagatatg acagcagatc
    29761 atagcttttt ttatccaaaa taatcacgtt catacctccc ttctataaaa catcactacc
    29821 acacagcctt atcagtttac cattttacct atctgtagga aagaatacta ggccaaagtc
    29881 aatttctaaa taggaaaaaa cgaacgatca ttagttttct gaagataaaa ttcctaatta
    29941 gttcgctttt ttcttttata attgtaatag ttgaattaat tattaaactt tgtctaaaat
    30001 aagaggcttt ttatcccaga ttgcaacaag ggttaacacc ttgaccttaa gcctagctaa
    30061 gcagctctca ctaagttact agctgctgcc ttaatgccgg ctaccttttt ggccataata
    30121 ggcatttgga ccatgctttc taaggtaatg cttgtccata atataggttg gagctggctc
    30181 cacacgagga ttgatttgtt ctgtcaggcg gttcatcttg gccacctctt cgagcaccac
    30241 tgagtgataa accgctaatt caggcgtctt gccccaagta aagggaccat gattgcgaac
    30301 aacaatacca ggcactgcca tcggatcaag accacgacta gcaaattcct ctaaaataac
    30361 cgtacccgtt tctttttcat aggctccatt aacctcatcg gcagttagag agcgagcaca
    30421 tggaatgggg ccataaaagt aatcagcatg agttgtccca taaaatggaa tatctcgccc
    30481 agcctgtgcc cagccaaccg cttctgttga gtgtgtgtgc acaatcccgc caacctctgg
    30541 ccatgccttg tataattgca catgggttgg caaatcagaa gaagggttca gctctccctc
    30601 aacaatagtg ccatctaagt ctgtaacgac catattttcc ggtgttaatt ggtcatagtc
    30661 aacgccgctt ggcttgatga cgatacgtcc cagctcacga cagacctctg agacattgcc
    30721 ccaggtaaat ttcaccagcc catgcagcgg tagggccttg ttggctgcac agacacgttc
    30781 acgcatttct tgtagccttt ttgccattag cttaaccccg ctttctcaat cagtggataa
    30841 aggaaatcct gtgcctcctt gatggcagct cttgtctcct ctacagtttc acagttttct
    30901 gaccacattt caatcaaaaa tggaccatga taatgcgttt tcttgagcac atcaaacatt
    30961 gcttcccaat caacacagcc ttgaccgaat ggcacatcac gaaattgccc tttagatgtt
    31021 tctgtcacag cataggtgtc ctttagatgc aaggcagcaa tagaccgatg cccattgtaa
    31081 aattcactcc agaggtcatt atgccaagca gagacattgc ccgtatctgg atagacaaag
    31141 agataagggg agtcaatttc tttttccaca gctaggtatt tctcaattga gttgataaaa
    31201 ggatcgtcca ttatttcaat ggctaaaata acctgagctt cctctgccca agtgcaggcc
    31261 tgtctgagat ttttgataaa gcgcgcacgc gtttcaggtg atttttcttc ataataaacg
    31321 tcatagccag ccaattgaat ggtacgcaca ccaagatcct gtgctagcac aatgcatttt
    31381 ttcattagct ctaatgatgt cgcttctgtt tctggattgc tagagccaag tggataacga
    31441 cgatgaccag agaagcaaat gcttgggata cgaacccctg tttcataaat agccttgaca
    31501 atgtctagtc gctcctgttt actccaatcc aagcgcgcta ggcgagcatc tgattcatcg
    31561 acagacattt ctacaaaatc aaagcctaat acctttgcaa attgcaagcg ttccagccaa
    31621 gtaaaatgct ttggcgttgc tttttcatat ataccaatag gacgcgccat attgttaccc
    31681 ccaaatgcgt cgaatctcgt ctttaaaggc acgtgccgct gctgcaggat cctctgcttc
    31741 agtgatacca cgacctgcaa taaaggtaaa gacattaacc ccttcaaaga gcttgagggt
    31801 attgatatct aagccacccg tcaccgatac acgaaagccc atgtcaatga gggctttgac
    31861 cttgttcaga tctttttcac cccatacttc accagcgagt agggcgtcac gtgattgatg
    31921 gtaaatcgcc tgtgaaatgc ctgcatctag ccacaattgt gcctgttcat aggtccaatc
    31981 accatacagc tcaacctgaa tctcgccacg ttccccacgc tcttctttga tggctttcag
    32041 tgcggctgcc atggttggaa tagtggcaca gcaaatacaa gtcatccagt ccgcaccacg
    32101 cttagcatta ttcttagcaa cagtaccgcc agcgtctgca cacttggtgt ctgctacgat
    32161 gatcttctct ggaaataagc tacgcagcac ctcaaccaat tcgctgccta cttgaagcag
    32221 gcaaactgtc cctgcttcga ttacatcaac ctcgtgacca actgcaacag cagccctgac
    32281 cgccccctgc aaatcagaat gatctaaggc aacctgtaat tttggaatat gtgtcatgat
    32341 tttctaccaa gagcccgtag caccgccttc aatgcttaat agcgagctcc tatcctttct
    32401 gttgtgtttg attcgtttag tgatgatggc ttgtctaaga atccaaatcc aagccctcta
    32461 aataaggact atttttggac tcgtccacca aagccaaaac ctctgctgga gtgtgacagg
    32521 caactaagcg cgaaatagcg tcttccagtt caaaaagggc gacaatctgt ggaatagcaa
    32581 ctgttgtatg aatagaagga tcagttgccg ccaaggttag caataccgaa gcctctttgc
    32641 catctgaaaa ggtcaccggc ttggtcagtg tgataagagc aaaggcattt cgcttgaccc
    32701 ctacaccagc ctctgcgtgt ggcatggcca ttcccggcat aaggacataa tagggcccgt
    32761 acttttctgt tgatgcgata atagcgtcat aatattcaga ggtcaccgcc ccgctgtcaa
    32821 tcaaaggctg aacagctagc ttaaccgctt cctgccagct agctgctgac aagcccaagc
    32881 gaatagagtt gttttcgata aatgcttttt ttaaattcat ataactatcc tttctaaatc
    32941 aaattctttg gccagacact ttttgcctca ctcctatcta gctgataaag agaaagagct
    33001 ggaatctctc ttcacaactc tcactccatc tatccttact gaaagttgat tgctacagct
    33061 tagcttacag ccaagtggct gctcttaggc tcactatcat ttgccatgag cagcactgat
    33121 gtcatcaggg ccgctctaaa gcaccgcctg tagcttggtt ttgatttcat tgtcgtccat
    33181 aagattatct agtccaacca aatgaccctt tgtacgccca tctaattcat gaatcaggtg
    33241 attagaagca accacaatat catagcctga ggcaagtccc tttgcctcac ccactgagca
    33301 agaagcagac tgaatatcag tcaccccaag ctgacgaagt gcgttttcaa ccttcatttt
    33361 aataaccatt gatgacccca tgccattacc gcatgctgta agaaccttaa ccatttattt
    33421 tcctccgaat atatgataat ttgatatgaa tgaagacctg cagaagtata tcgacaaact
    33481 cctaccagcc tgtgctaaaa gacgaataag cagctattat caccttgctt attgtgcttc
    33541 accgcggtag taagcctctt tatccttagc cctagcaaat tgtagctgtg gaatagcaag
    33601 taagaagaca cacaccacca catagcctgc aataccaagg aacttgaaga gataaccaaa
    33661 tggaagccaa ggaagcacca ggtcaatatt gccatgataa ccacctgtca agcccaacag
    33721 accaactgcc actgcaccta aggcaacctg aagaatacct gatataaagg atagagcaac
    33781 agctgccttc cagccaccac gcttatctgc ataaacagca atcgcagcat tatcaaagaa
    33841 gaccggaaca aatcctgtga tgatcaagat tggattttta aagatcacaa gaagtgcaat
    33901 agtgattagc tgaccgataa gcccaaaggt aaatcctgac aaaacagcgt ttgaagagcc
    33961 aaagccatat gacgctgcaa cgtccaccgc aggaaatgaa cccggaagga gcttacttga
    34021 aatcccttgg aaggcattgg tcaactctga cacaaacata cgcacaccct gcatcaggat
    34081 aaagagataa actgagaaag ttaaggaggt ttgcaaaata tacataaaga aggcctgctt
    34141 agctggatta aaggcaccag cacctataag ttctgcatta gacatcatat ctgggccaag
    34201 cacagccaag atagcaccaa agaaaaccag cattagagtg gcagaagcaa ccaccgtatc
    34261 atgaaaaatc gttaaaaagc ttgctagctt aagattgtca aggttctctt cttttttacc
    34321 aaagaaaggc gccaccttgt caacaaacca gatcgcaaac tgctgctggt gcccaatggc
    34381 aaagcctcca ccacctgtca agcgctgagt cgcctcaact gtcatattgg agctgacagc
    34441 ccagtaaagg ccacagataa taccgaccgc ccaagcacca aaagcatttt gaagctgagg
    34501 gattaaaaga agaacaaaca cagagatggt tgccgcctgc tgcaccatga tatgacccgt
    34561 aataaagagc gtacgaacct ttgtcacctt acgaagcgcc actagcaaaa tattgacccc
    34621 aaaaccgatc aaaagggctg tggtggcaac gctgatggat cccatctcct ctagcttggt
    34681 attggctgct gcaagtccaa agtaagggtc aataactgcg gcctttaatt caaatttctt
    34741 acccaatgcc actaggattg ggcgaaaggt gttaaccaag cccccagcac caacattcaa
    34801 aatcagataa ccaaccgttg ccttaacaaa gccagcaaat acttcatgca ggggcttttt
    34861 aagcagcaaa tacccaatca aaaccaaaag acctacaaag aaagccggat tttgcaaaat
    34921 atcttgcgaa aaccagttta ggggagctat aagcattttc ataagaacta cctcttttca
    34981 cagttaataa atatgatatt ttctatacaa taattgtaaa cgatgtaagc gtttaaaaaa
    35041 aagaccaaca atcacacaaa gaagtgttca aaaatgtact gaagccaatt tccagctagc
    35101 tctgatcact gttaaagcac tatcattaat ctctaattaa taaccaaaca catcacaaca
    35161 atatcgggct aacacaaaaa taggccagcc catactgccc agccaaaacg aaacaagcaa
    35221 tcaattcaag gcacttaacc ctgttttata tcgtacaaag cccttttaag atgattttgt
    35281 ttgtttccta atcgtaaatt agttatctga tccgttctct cctcagatat actcaccctt
    35341 atctaattct actgtcaaat agctacttac tcataagcaa atgaatatta agcaaccacc
    35401 aagctacaat aaaagacctt accctgttgg caagatctta ttcattatac aatttttcct
    35461 tctgcgacat ggactacctc atcacacaag tcttcaatat ctgtcttcag atgtgagctt
    35521 aaaatcacaa gcccattttt gctaacatct aaaagcaatt ttttcgtttg ctccacgctc
    35581 ctgtcatcta atgcattcat tggctcatct aatataagga tcttagggtg atgcatcaag
    35641 gcctgaatta accctaattt tttcttagtg cctagcgatt aatgcttaaa tgctgtttga
    35701 ctaaactgat gtaaatgata aacatctaac caaaaagcta aatcaatatc tctagcctta
    35761 ggagagattg acctaagcaa ctctagattt tgtaacaatg ttaaatgtgc aataaactct
    35821 ggattctcaa tcaaaatccc agcatcctcg atataattat ggtactgtct aattttttta
    35881 ttgtcctgat aaacagctcc ttcatctaat ttgatataac cagctaaggc cttaagtatc
    35941 aaggtttttc ccgaaccatt aatacctacc aaaccataga tattaccttc tttaaaagta
    36001 agattaatat catctagaac aaggttaccc ttatacagtt ttctaccatg ttcaatccgt
    36061 aacatctcag ctctccttat aataattgtc ataaagcata tgtaccaata ctattagcag
    36121 caggcaccac caaacatcaa acaaaaagta acgtatcaag gtgagactag caaacaagat
    36181 catagctact acagcagatg aggcatagcg tatcataaca taaatcaagc aaatatctat
    36241 agtaagccaa gataccataa gataacatag tcgttcaata tgatatggtg caccataata
    36301 ggtcatcaat acacctaata ttaaaacgat aaaaagtaac cactctttaa tatagaaaat
    36361 cgtactcgtc cgccatagct tgttaaaaaa taccaactga cttcgagcat gaaaacgaaa
    36421 gatttcctta gttccttcag ccaaatccgc caaaaatgaa atcgtaaaat aaaagctgtt
    36481 gaaggacaag cctagcaagg tgataacctt gacaaaatca gctgtctccc cttcaatcac
    36541 tggaaacggc attagcaacc gatagcacac taaattatga aaatctcgct ccccagtcat
    36601 attagcctta atcaataaaa gatgtattag taagccagta agacatgctt tcattccaac
    36661 aaccagcagg ttagataatt tcatggtgct tcctcaattt taaaacgatg cacacaccca
    36721 ctaagcctaa ataaggtgat aaaaggtaag gaatatcagc atcactataa gatgttgaca
    36781 tcaaagaagt cataagaaca tatttgggag gtaaatagct atataacaac ggtgacaaag
    36841 cccacatcaa aatcaaatag agcatgcttg acttaataaa ggattgaaga tagtcaacaa
    36901 gaaaacaaac gaaatacgta tgaacgaaca aagctaacga ttttactaag caatagtaag
    36961 ctataaaggt tgttgctcct tgaccaaaaa aacgcaatat tgagttttga tcaaaataag
    37021 gcattaaatt accgttcata tgggcaacac catttagcca agacactaaa gtcaaagcaa
    37081 atattacaat gtaaaaactc agtaaaacat ataagctcaa ctgaagcttt aaaaaaatac
    37141 accttttacc atagtcagac tttctgccaa tgaggtattt aagatgtctt gacttaaggt
    37201 aatagtaggc ataggccact aaaatcatca ctagtggata gataaaagat tgataaaaac
    37261 taaaatcaaa caccacacta tccaaacgta tcatactcaa caatagactt ttctttacct
    37321 caattccacc agataaatct actgcacttg tatcaaaaaa taagatatgc ttcaaactgt
    37381 caaaataaat aaaacctaaa aatagtaacg ggactaatgg ataaaaatag cgaaatggaa
    37441 ataatctata ctgtagcatt tatgaataac tcccctacaa aaaatcaagg aaacgcctcg
    37501 ttactaactc aattcacaat tgtagatatt taccaattgt ctggagacca actaccacta
    37561 atggttgttg ctccgtccca ccaattttca cgtaccagat gcaaggcata aaggtaccca
    37621 cttttagtat cctgtgtata aattcctctg tcgcctgtcc aagttttatc tatatcactt
    37681 cttctttgac cgttactatt agctagatag tgccttacca caatttctct attacgtcct
    37741 cttgaatcta aattaacgac ataataaggc gccgcactct tcacaagata atctttcgtc
    37801 cttccaaaag atgacgtgat tctaaaattt tgcaagtaac caatttgtcg ttctgctata
    37861 actaaagaac taatcaataa tgtagaagct acaattgcca ataatccaat cttaattttg
    37921 cctaatttta ttttttaata atttataatt tttatatatt tagcacatca tcagcgcttc
    37981 cttgacaatt gataatacaa ttcatgctag gcttaatcga taaa
//
LOCUS       DARYLD010000016        33302 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYLD010000016 DARYLD010000000
VERSION     DARYLD010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33302
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            67..1245
                     /locus_tag="TU651_000677"
     CDS             67..1245
                     /locus_tag="TU651_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0896698.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            1350..2312
                     /locus_tag="TU651_000678"
     CDS             1350..2312
                     /locus_tag="TU651_000678"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL0896699.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            2672..3442
                     /gene="recO"
                     /locus_tag="TU651_000679"
     CDS             2672..3442
                     /gene="recO"
                     /locus_tag="TU651_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL0896700.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            3558..4565
                     /gene="plsX"
                     /locus_tag="TU651_000680"
     CDS             3558..4565
                     /gene="plsX"
                     /locus_tag="TU651_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL0896701.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            4558..4806
                     /locus_tag="TU651_000681"
     CDS             4558..4806
                     /locus_tag="TU651_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL0896702.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            4956..5666
                     /locus_tag="TU651_000682"
     CDS             4956..5666
                     /locus_tag="TU651_000682"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL0896703.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            5845..9585
                     /locus_tag="TU651_000683"
     CDS             5845..9585
                     /locus_tag="TU651_000683"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL0896704.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAEDLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            9704..11161
                     /locus_tag="TU651_000684"
     CDS             9704..11161
                     /locus_tag="TU651_000684"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL0896705.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            11218..12240
                     /locus_tag="TU651_000685"
     CDS             11218..12240
                     /locus_tag="TU651_000685"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL0896706.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            12237..12794
                     /gene="purN"
                     /locus_tag="TU651_000686"
     CDS             12237..12794
                     /gene="purN"
                     /locus_tag="TU651_000686"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL0896707.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            12941..14488
                     /gene="purH"
                     /locus_tag="TU651_000687"
     CDS             12941..14488
                     /gene="purH"
                     /locus_tag="TU651_000687"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL0896708.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(14866..16020)
                     /locus_tag="TU651_000688"
     CDS             complement(14866..16020)
                     /locus_tag="TU651_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL0896709.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            16411..17673
                     /gene="purD"
                     /locus_tag="TU651_000689"
     CDS             16411..17673
                     /gene="purD"
                     /locus_tag="TU651_000689"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL0896710.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            17900..18388
                     /gene="purE"
                     /locus_tag="TU651_000690"
     CDS             17900..18388
                     /gene="purE"
                     /locus_tag="TU651_000690"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL0896711.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            18375..19448
                     /gene="purK"
                     /locus_tag="TU651_000691"
     CDS             18375..19448
                     /gene="purK"
                     /locus_tag="TU651_000691"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL0896712.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            19463..19687
                     /locus_tag="TU651_000692"
     CDS             19463..19687
                     /locus_tag="TU651_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL0896713.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            20284..21576
                     /gene="purB"
                     /locus_tag="TU651_000693"
     CDS             20284..21576
                     /gene="purB"
                     /locus_tag="TU651_000693"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL0896714.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            21874..22787
                     /locus_tag="TU651_000694"
                     /pseudo
     CDS             21874..22787
                     /locus_tag="TU651_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            22870..22968
                     /locus_tag="TU651_000695"
     CDS             22870..22968
                     /locus_tag="TU651_000695"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL0896715.1"
                     /translation="MFKKYQYYLFLAALFLLHSAQLLSDIDWWRVG"
     gene            23002..24009
                     /gene="ruvB"
                     /locus_tag="TU651_000696"
     CDS             23002..24009
                     /gene="ruvB"
                     /locus_tag="TU651_000696"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL0896716.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            24250..24708
                     /locus_tag="TU651_000697"
     CDS             24250..24708
                     /locus_tag="TU651_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL0896717.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            24714..25115
                     /locus_tag="TU651_000698"
     CDS             24714..25115
                     /locus_tag="TU651_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896718.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            25112..26893
                     /locus_tag="TU651_000699"
     CDS             25112..26893
                     /locus_tag="TU651_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL0896719.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            27313..29955
                     /gene="adhE"
                     /locus_tag="TU651_000700"
                     /gene_synonym="adhC"
     CDS             27313..29955
                     /gene="adhE"
                     /locus_tag="TU651_000700"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL0896720.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            30450..31502
                     /locus_tag="TU651_000701"
     CDS             30450..31502
                     /locus_tag="TU651_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL0896721.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            31705..32721
                     /gene="adhP"
                     /locus_tag="TU651_000702"
     CDS             31705..32721
                     /gene="adhP"
                     /locus_tag="TU651_000702"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL0896722.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
BASE COUNT         9548 a         6007 c         7873 g         9874 t
ORIGIN      
        1 acattaaacg cttgattttt tgatagaata taatgtgtct tatcgaaaag gagtaatttt
       61 tttagtatga aaaaaagaat tctatcagcg gttcttgtaa gcggtgtgac ccttggaaca
      121 gcaactacag tgggagcgga tgatttagat tccaaaatag cgttgcaaaa ttcagttatt
      181 tctaatttaa ataaagaaca aaaagctgcg caggatagaa tgaagacttt gcaaagtcag
      241 gttagctcat tacaatctga acaagaaagg ttagtcgcta aaaatggtga gcttgaagcg
      301 cgatctgctc agtttgagca ggagattcaa gtgcttgcca gtcaaattat tgctcgtaat
      361 gaaaagttaa aaggacaggc tcgtagtgct caaaagggaa atacgttagg ttacctcaat
      421 gcacttttga attctaagtc aatttctgac gttattactc gtttggttgc tattaataga
      481 gctgtgtcag ccaatgcaca gatgttggaa aagcaaaagg ctgataagct ttctcttgaa
      541 gaaaagcaac aggaaaatca agaagcgatt aatacaattg cttcaaatat tacagcaatt
      601 gaatcaaacc aagtagcttt aaagactcaa caagcagatt tagaggttgc caaggtagat
      661 ttggcgcttc aattagcaac tgctgaggac gagaaggcta gcttgattac ccgtaaagag
      721 gctgcagagc aggcagcagc tcaagccaag gctcaggcag agcaggaagc agcagccaga
      781 gcagcacagg ctcaagctca agcacagtct gtagcggcag ctcaagcagc agtgactcaa
      841 gccgtaccaa caccagctcc agcgcaggca cagcctgttg tggcgccagc agctatggtt
      901 tcaacaccag cggtgtcgta tgcctatgat ccttctaatc cgtaccctgt cggccaatgt
      961 acttggggag ttaaggcttt agctccttgg gttggcaatt attggggaaa tggtggtcaa
     1021 tgggcatcaa gtgcagcggc agcaggtttc cgtgtaggtg caacaccaat ggttggctct
     1081 gttgttgtat ggaatgatgg tggctatggt cacgttgcct acgtaacagg tgttcagggt
     1141 ggacagattc aagttatgga agccaactat gctggaaatc aatctattgg caattatcgt
     1201 ggttggttta gcccaggtgc tgtatcgtat atttatccaa attagaaaat aagtaaaggt
     1261 aagaatcagg attcttacct ttttatttcc attgaaaaat tgattgaaaa gggttaaaat
     1321 ggtataggat caaaactttg gaggaaaaaa tgtcttattc tgatttaaag ctgtttgcat
     1381 tatcgtcaaa caaggaatta gcagaaaaag ttgctgctgc gatgggaatt caacttggga
     1441 agtctacggt tcgccagttt tcagatggtg agattcaggt caatattgag gaatcaatac
     1501 gtggacacca tgtttttatt ttgcagtcaa caagctcgcc tgttaatgat aacctaatgg
     1561 aaattttaat tatggttgat gctttaaagc gtgccagtgc tgagaaaatt tctgtggtaa
     1621 tgccttatta tggctatgct cgtcaggatc gtaaggctcg ttcgcgtgag cctattacct
     1681 ctaaattagt cgctaatatg ctagaggtgg caggtgttga tcgtttattg actgttgatt
     1741 tacatgctgc gcagattcaa ggcttctttg atattcctgt tgatcatctc atgggagcac
     1801 ctttaattgc tgattatttt gatcgtcatg gtctagtagg tgatgacgtt gttgttgtta
     1861 gcccagatca tggtggtgtg acgcgtgctc gtaagctggc acaattcctc caaacgccaa
     1921 ttgctattat tgataagcgt cgtagtgttg ataaaatgaa taccagtgag gtgatgaata
     1981 tcattggtag tgttgaaggt aaaaaatgta ttctgattga tgatatgatt gatactgctg
     2041 gtaccatctg tcatgccgct gatgcgcttg ctgaagcagg agcaacagca gtttacgcat
     2101 catgtactca cccagtgctg tcaggaccag ctcttgataa tattcaaaaa tcagcgattg
     2161 aaaaattgat tgttttggat acgatctatt taccagaaga aagactgatt gataagattg
     2221 aacaaatctc tattgcagat ttgattgcgg aagctatcat tcgtatccat gaaaaacgtc
     2281 cattgtcacc cctatttgaa ttagggaaat gataaggtta gcctgaggta gtaagcctta
     2341 ggctttttta tgttttaaaa ggctatttga ttaccaaagc agtgtttgat ttaacgccat
     2401 agataggctt cactgtctta tggtaggtgt tgagctatta tagcaaaaag tcatgtgtag
     2461 gtgctgtgtt taaacagcta gcctatgatt catatagtta tggctagtga ctgttgagct
     2521 tcttattctc agagttgtta cgagccttaa gtacagtgtt agtcatgcaa ttttcctgga
     2581 ttttgggtat aatatagctg tatttaaggt gttttaaagg tctagtaaga aaggcattat
     2641 tactagctga gaagcttggt tatggagata tatgcgtatt cagaggtcac ttggtattgt
     2701 cttgtacaat aaaaactatc gtgaagatga taagctcgta aaaatattta cagaagcggc
     2761 gggcaagcgt atgtttttcg tgaaacatat tggtcgttct aaactagctc ctgtggtcca
     2821 gcctttaacg gctgctgatt ttctattgaa aatcaatgat tcgagccttt cttatataga
     2881 ggattataat caggtggagg cttatcggca catcaatgaa gattttttta ggctatccta
     2941 tgctagttat gtcttggctc tggctgatgc ggctattcca gataatgagc ctgatcctca
     3001 gttgtttgct tttttgaaaa agactcttga tctgatggaa gaagggctag attatgacat
     3061 tttaacgaat atctttgaag tccagatttt ggatcgtttt ggggtgagaa tgaattttca
     3121 tgattgtgtt ttttgtcaca gaaccaatct gccttttgat ttttctcata agtattcagg
     3181 tgtcctttgt ccgcagcatt accatgagga tgagaggcga tatggcttgg atcccaatgt
     3241 gatttatttg cttaatcgtt ttcaaacgct taatattgat gagctaaaga ctatttctgt
     3301 gaatactggt atgaaaaaaa agcttcgtct ttttattgat gccttgtatg aggattatgt
     3361 cggtattcgt ctaaaaagta aggtttttat tgatgatttg gctaagtggg gagatattat
     3421 gaaaaacaag cagggcttgt gagctattca ggtgtggatt tgtcctttta tgggaattgt
     3481 ctggggaata tgctataata gttacgttat tctctaggat atttttcgtt aagaaaaata
     3541 ggattaaagg agcaaaaatg aagaaaattg caatagacgc tatgggtggt gattatgccc
     3601 ctaaagctat tgttgagggt gttaatcagg cgatagaatc cttttcagat attgaaattc
     3661 agctttatgg cgatcaatca aggattgagt cttacctagt taaatcagat cgtgtgtcca
     3721 ttgttcatac agatgaaaaa attaattctg atgatgagcc agcaaaggct attcgtcgta
     3781 agaagaatgc ttctatggtt ttagctgcaa gggcagttaa ggatggtcgg gctgatgcag
     3841 ttctttcggc aggtaataca ggcgccttgt tagctgctgg tttgtttatt attggtcgta
     3901 tcaagggagt ggatcgtcct ggtttgctgt caactctgcc aacggttgat ggttcaggct
     3961 ttgacatgtt agatttgggt gccaatgctg aaaacacagc agagcattta caccaatatg
     4021 ctattttagg ctctttttat gcaaaacatg tgcgtggtat tgccaagcct cggattggct
     4081 tgcttaataa tggtactgag gcaactaagg gtgattctct tcgcaaggag gtctataatt
     4141 ttttagcttc agacagcagc ctacagttta ttgggaatgt tgaggcaaga gatttgatgt
     4201 ctggcgtggc agatgttgtg gtagcagatg gctttacagg aaatgctgtt ttgaagtcga
     4261 ttgaaggcac tgctatgagt attatgggac aattgaaatc agctatagca gtaggtggtg
     4321 ttaaggcaaa gtttggagct cttttattga agagtagcct ttatgactta aaggatactt
     4381 tagattattc cagtgcgggt ggggctgtat tgtttggtct taaagcacct cttgtgaaat
     4441 cacatggttc tagtgatgcc aaggctattt ttcataccat taagcaggtt cgtacgatgc
     4501 tagaaacaga tgtagttggc caattagttg aggagttttc taaggagagt gatgtaaatg
     4561 actgaggaag ttattttaga gaaaatcatc gcattaatca agaagcaaag aagtcgtata
     4621 gactttgaca ttacagaaaa aacagcacta aaggatgatt taggagtaga ttcgattgaa
     4681 ctggtagagt ttgttattaa tatcgaagat gaatttggta ttgatattcc tgatgaagat
     4741 gttgatggca tggtatctat gggagatatg ctaaattatt tggtcaagcg tttaaaccaa
     4801 agctaaatag ttttaaaaga gcaccagctc tttttttgtt tccgaaaaaa cgaacattat
     4861 aagtttattt tatattaaat gtaaataaat gttgaatatt tagtatgttt gtggtattgt
     4921 ttagatatta aatgcaaaga aaggcgaaca aataagtgtc taatcaactc atttattcag
     4981 gtaaggcaaa ggatatctat gaaacagccg atgacgggat tgtcttaatc tcctacaagg
     5041 atcaggtcac tatgctaaat ggagcacata aggaaatgat tgaaggaaaa gggagcctta
     5101 ataatcagat ttctgcctta atctttgata ggctaaatag ggttggcgta tcaactcatt
     5161 ttattaagca attatccgag acagaacagt taaataaaag ggttgcgatt attcctttgg
     5221 aggttgtttt acgaaacgtg gccgctggct cattttcaaa gcgctttggt gttaaagaag
     5281 gtcaggcttt ggacgagcca attattgagc tttattacaa gaatgacgct ttagatgatc
     5341 ctttcattaa tgatgagcat gtcagctttt taaagcttgc gactgatgag cagatagcct
     5401 acatcaaaca agagacgcat cgtattaatg cttatttgaa ggagtggttt gctagtgttg
     5461 ggttgacact ggttgatttt aagctagaat ttggctttga taaggagggg atgcttatcc
     5521 ttgctgatga gttttctccg gataattgcc gcttgtggga taatgcgggc cgtcacatgg
     5581 ataaggacgt ttttcgtcgt cagcttggca gtttgacgca agcctatgag actgttttag
     5641 aaaggctaag agcattggat caataaagac cagcttattt gttgtcagtt aagaaaggga
     5701 gctctttttt gtccgtcatg taagaaaata aatcagttca gactatttga gctgctgtct
     5761 aagaaaggct gtctgctatt ggagaaaaga gtcaggctag ttcttatttt gggctggttt
     5821 ctgattggac ttggtatatt aactatgaat aaacgtattt ttgttgaaaa gaaggctgat
     5881 tttcagatta aggcacaggt cctgttaaag gaattgaaac atcagctgca gttaaagaca
     5941 ctggttgatt tgcgtattgt gcaggtttat gatgtgtttc atttggatca ggagctgctt
     6001 ttaacagcta taaagcatgt tttctctgag caggtcactg atcaggtatt gtcagaagaa
     6061 gctttacaag cagatttaaa aaggtatgcc ttttttgcga ttgaagctct gcctggacag
     6121 tttgatcagc gtgcggcaag ctctcaggaa gccttattgt tgttaggagc ctcaactgat
     6181 gtgactgttt tgacctcaca gctttatttg gtcaatcaag acattgctgc tgaagaatta
     6241 gaagccttaa agcagtactt gttaaatcca gtggattcta ggtttaagga catattagcc
     6301 ggtcttgatg atcaggattt ttcagtagca gataaagtga ttccaacgct tgatgttttt
     6361 aatgattata cagcggaaga tcttgctcgt tacaggtctg agcagggcct agcaatggaa
     6421 gtggaggatc tgctgtttat tcaggattat ttcaagacaa aggggcgagt gccaacagag
     6481 actgaactaa gggttttgga tacgtattgg tctgatcatt gtcgtcacac aacctttgaa
     6541 acagagctaa aaacgcttga tttttcagct tctcattttg aaaagcagct ccaagctacc
     6601 tatgagacct accttgctat gcgtgatgag ctaggtcgat ctgaaaggcc tcaaacgctt
     6661 atggatatgg ctaccatttt tggacgttat gaaagagcta atggtcgttt agaggatttg
     6721 gaggtttcag atgaaatcaa tgcttactca gtggaaattg aggtagatgt tgatggtgtc
     6781 aaggagcctt ggctgctcat gtttaaaaat gaaacacata atcacccaac ggaaattgaa
     6841 ccctttgggg gtgctgcaac ctgtattggt ggagctattc gtgatcctct gtcaggccgt
     6901 tcctatgttt atcaagccat gcggctttct ggtgcagggg acattacaag cccgctgtca
     6961 gagactcgta agggcaaatt accacagcag gttatttcga ggcaagcagc acatggttac
     7021 tcgtcatatg gcaatcaaat tgggctagcg actacttatg ttcgtgagta ttttcaccca
     7081 ggctttgttg ccaaacgtat ggagcttggt gcggtagttg gtgctgcacc caaggaaaat
     7141 gtggttcgtg aaaagccaag gacaggtgac gtggtggttt tgcttggtgg gaaaacagga
     7201 cgtgatggta ttggtggtgc gacaggatca tctaaggttc agacagttga gtctgtagaa
     7261 acagctggtg cagaggtcca aaaaggaaat gccattgagg agcgtaaaat ccaacgtctt
     7321 tttcgtcgtg gcgatgtgac acgcctcatc aagaagtcaa atgattttgg tgctggtggt
     7381 gtttgtgtag ccattggcga gcttgctgct ggtcttaaca ttaacttaga taagattcct
     7441 ttaaaatatg ctgggctaaa tggaacagaa attgccattt cagaatccca agagcgtatg
     7501 gctgtcgtga tttgtccaaa ggatttagag gcctttatga gcgcctgcca taaggaaaat
     7561 atccatgctg ctgttgtggc agctgtgaca gaaaaaccga atcttgttat gacctggaat
     7621 gggcagacga ttgttgatat tgaacgctca tttttagaga caaatggtgt gcgcgtgtct
     7681 gttgctgcta aggttgttga cagtggtgcg ccaataccag aagctcgtca aactactgct
     7741 gagacacttg aagcagatac cattgctgtc ttatcagacc tgaaccatgc tagtcaaaag
     7801 ggtttgcaaa ccctgtttga tagctcagtg ggtcgctcta cagtaataca tccgcttggt
     7861 gggcgctatc aaatgacacc tgttgaaggc tctgttcaga aattaccagt tcaacatgga
     7921 gtgacaaaga cagtctctgt tatcgctcaa ggctatcacc cttatatagc cgaatggtca
     7981 ccttatcatg gtgctgctta tgctgtaatt gaggcaactg ctcgtctggt cgcaacgggt
     8041 agccattggc ataaggcacg cttttcatat caggaatatt tccaaagaat ggataagcag
     8101 gcagagcgct ttggtcaacc ggtggcagcc ttgcttggag caattgaagc acaggtgcag
     8161 cttggcttgc cttctattgg aggtaaggat tcaatgtctg gtagctttga ggaattgaca
     8221 gtgccgccga ccttggttgc ctttggtgtg acgactgctc atgtagatca tatcctttca
     8281 ccagaattta aagctgctgg cgagaatatt tactatattc caggacaggc tatttcggaa
     8341 gtgattgatt ttgagttgat aaaatctaat tttatgactt ttgaggctat tcagaaaaag
     8401 cataatatta gctcagcttc ggctgttaaa tatggtggtg ttgttgaagc actggctctt
     8461 gctgcctttg gtaatcggtt aggggcttgt gtgacattac cagagcttga caggagctta
     8521 acagctcagc ttggtggctt tatctttaca tcaaaagagg aaatcacagg tgttatcaag
     8581 cttggtcaaa ctaccagtga ctttacattg gttgtcaatg atgtcaagct atctggagct
     8641 cgtctcttaa aggcttttga agggagcctg gagcaggttt acccgacggt atttcagcag
     8701 gcaggtgaat tgaagcctgt tcctgtagtg acaacagcac ttgctgctca gtttaaggaa
     8761 aaaatagctc agccagttgt ctatattcca gtttttccag gaactaactc agaatatgat
     8821 tcggctaagg cctttgaaag agagggtgca agggtgaact tggtgccttt tgttaccttg
     8881 aatgaggcag ctattgacgc ttcagttgac acgatggttg accatattca tcaagctcat
     8941 attatcttcc ttgcaggtgg tttttcagcg gcagatgagc cagatggttc agctaaattt
     9001 attgttaata tcctgctgaa tgagaaggtt cgaatggcga ttgatgcctt tattgaaaag
     9061 ggtggtctga ttatcggtat ttgtaatggc tttcaagctc tggtcaaatc agggctgctg
     9121 ccatatggac gttttgaggc ggtacatgag gctagtccaa ctctgtttta taatgatgcc
     9181 aatcagcatg tggctaaaat ggtagaaacg cgtattgcca ataccaattc tccttggctg
     9241 gcaggtgtca gggtggggga tattcatgct gttgcagtgt cacatggaga gggcaagctt
     9301 gtggtaacag aaagagaatt agcagagctt tgtaaaaatg gtcagatttt tagccagtat
     9361 gttgaccttg atggtaatcc aagcatggat agcaggtata atccaaatgg ctctgtcaac
     9421 gctattgaag gtcttaccag caaaaatggt cagattatcg gtaagatggg acattcagag
     9481 cgctttgaag agggactttt ccaaaatatt ccgggtaata aggatcaatg gttattccga
     9541 agtgcggtgc attattttag aggagaccat gtgggtattg actgaactgg gatatagcct
     9601 tgtaatagct aagatagctg ctattattgc tcagcctagc tgttagttct agcttagtta
     9661 atgacacaat cataattaaa agggcattag cccagaggta aagatgacat atgacgtaaa
     9721 atctcttaat gaggaatgtg gtgtttttgg gatttgggga cacccacatg ccgctcaagt
     9781 gacttatttt gggcttcata gcctacagca ccgcggccaa gagggagcag gtattatttc
     9841 aaatgataat ggggagcttc atcagcatcg tgatgtaggt ctcttgtcag aggtgtttaa
     9901 ggattcatct gatctggaca agctaaaggg acatgctgcc attggtcatg tgcggtatgc
     9961 gactgctggg acggcttcca ttaataatat tcagcccttt ttatatcgtt ttacagacgc
    10021 tcaatttggc ttgtgccaca atggtaattt gaccaatgct atgtcattga aaaaagcgtt
    10081 agagagtgag ggagctattt ttaatgcctc ttctgataca gaaattctaa tgcatttgat
    10141 tcgtcgtagt catcacccag aatttttagg aaaggtaaaa gaggcactca acactgttaa
    10201 agggggcttt gcttacctgc tgatgacaga gaaccagctg atagcagcgc ttgatccaaa
    10261 cggctttagg ccgttgtcta taggccgtat gaaaaatggg gcttgggtcg tctcaagtga
    10321 gacctgtgcc tttgaagtgg ttggtgctga gtgggttcgc gatgtgatgc caggtgaggt
    10381 cattatcatt gatgatcagg ggatcactta tgactgctat acgactacta cgcagctggc
    10441 tatctgctct atggaatata tttactttgc gcgtcctgat tcaaccattg ctggagtcaa
    10501 tgttcacacc gctcgcaagc gaatgggaaa gagactggct caggaatttc agcatgaggc
    10561 tgatattgtg gttggtgtgc caaattcctc attatcagca gcgatgggct ttgcagaagc
    10621 atcaggcctg ccaaatgaaa tgggattggt caagaatcaa tatacccaac gaacctttat
    10681 ccaaccaact caggagcttc gtgagcaggg agttcgaatg aaactttcag ctgtttcagg
    10741 tgttgtcaag ggcaaaaggg ttgtgatggt agatgattct attgtcagag ggacaacctc
    10801 acgacgcatt gttaatttgc tgcgtgaagc aggagctaca gaggttcatg tagcaattgg
    10861 tagccctgag ctcaaatacc cttgctttta tgggattgat attcagacaa gacgggagct
    10921 gatttcagct aatcatactg ctgctgaggt ctgtgatatt atcggtgctg atagcctgac
    10981 ttatttgtca cttgatgggc ttatcgaggc tattggactt gatacaaaag caccaaatgg
    11041 tgggctttgt gtggcttatt ttgacggtca gtatccaacg ccgctttatg attatgagga
    11101 ggcttatctc aagagcttag aagaaaaggt aagctttcac attgatcagg tgacgaagta
    11161 gcgctttatg gctaacatag aataaatgat ctaggcagct aaaataagga ggagaaaatg
    11221 tctaaaaatg cttatgctca atcaggtgtc gatgttgaag caggctatga gcttgttgag
    11281 cgaataaaaa agcatgccga gcgtagcaaa cgattgggtg ttatgggtgg tctaggaggc
    11341 tttggtggtc tgtttgacct gtcaaagact ggtgttaagg agcctgtttt ggtttcaggg
    11401 acagatggcg tcggaacaaa gctaatgctt gcaatccagt acgataagca tgacacgatt
    11461 gggcaggatt gtgtggcaat gtgtgtcaat gatattattg cagcaggtgc cgaacccctg
    11521 tattttcttg attaccttgc agcaggaaaa aatgagcctg ccaaattaga gcaggtgatt
    11581 gcaggtattg ctgagggctg tgttcaagca ggtgctgctc ttatcggtgg agaaactgct
    11641 gagatgcctg gtatgtatgg tcaagatgac tatgatcttg ccggttttgc ggttggtatt
    11701 gctgagaaat ctcagctgat tgatggttca agagtagctg agggagatca tctcctaggt
    11761 ttggcatcaa gtggagttca ttcaaatggt tattccttgg ttcgtcgtat ttttgccggt
    11821 tatactggtg aggagctgct tccagagctt gatggaaaaa agcttaagga ggtacttctt
    11881 gagccaactc gtatttatgt caaggctgtg ttaccactca ttaaaagcgg cttagtggca
    11941 ggaatcgctc atattacggg tggcggcttt attgaaaacc tacctcgtat gttttccaaa
    12001 gaactagccg ctgaaattga agaagccagc ttacctgtgc tgcccatttt taaagtcctt
    12061 gagacatatg gtaagatcaa tcatgaagaa atgtttgaga tttttaatat gggtattggc
    12121 atggtgcttg ctgtcaagcc tgagcacgtt gagcaggtga aggcctgtct tgatgagcct
    12181 gtgtatgaca ttggtcgcgt tgtgaccaga acagttgcta gtgtggtgat gaagccatga
    12241 caagaattgc cgtttttgct tctggtaatg gctccaattt tcaaacgatt gcagaacagt
    12301 ttccggttgc ctttgttttt tctgatcatt gcgatgctca tgttttaagt agagcctgtg
    12361 ctttgggtgt tctgtcctac agctttgaac taaaggactt tgagaataag caagcctatg
    12421 agcagactct tgtggcattg ctgcagcggc atcagattga tctcatcgtc cttgccggct
    12481 atatgaaaat tgtgagtaca accttacttg atgcttacga aggaaaaatc atcaacattc
    12541 acccagctta tttgccagaa tttccaggag cacatggtat tttagatgct tggcaagcag
    12601 gtgttagtca gtcaggagtg actgttcatt gggttgatag tggtattgat acaggaaaaa
    12661 tcatcaaaca ggtacgagta ccacgtttga gtgatgatac tcttgaaagc tttgaagcca
    12721 gaattcatga agcagaatac caattgtatc cagaggtact ggatagtctt ggagtagagc
    12781 ggcttaaccg ctgattgtgt aagattaata actattttcc ctattgtggc atttcgttta
    12841 tcatagcagc tgcgctaatg gtggctaaca aaggctagaa gacttgtttg atgatggcac
    12901 tgctattgag gaaaatagac ttttctaagg agaacttaaa atgactaaac gcgccttaat
    12961 tagcgtatca gataaaagag ggattgtgga ccttgctagg gagcttaagc atcttggctg
    13021 ggatattata tcaacaggag gaacaaggct tgctcttgaa gaggctggtg tagttactgt
    13081 tgctattgac gatgtgacag gctttcctga aatgatggac ggacgggtaa aaacgctgca
    13141 ccctctcatt catggtggct tacttgctcg tcgtgacatt gagcaccact tacaggcagc
    13201 aaagcaaaac aggattgaat taatagacct tgttgttgtt aacctttatc ccttcaaaga
    13261 aaccatttgc cgtccagatg tcacttatga tgtcgctgtt gatatggttg atattggtgg
    13321 tccttcactg ctgcgttcag cggctaaaaa tcatgctagt gttacggtag tggttgatcc
    13381 gacagattat ccgctcgttt taggagagtt ggctagcact ggcagtacaa gttaccaaac
    13441 ccgtcaaagc ttagcagcta aagcttttcg ccatactgca gcctatgatg cagtgattgc
    13501 agattatttt acaagacaag caggtgagac aaagcctgaa aagctcacgc ttacctatga
    13561 tttgaagcaa agcatgcgtt acggtgaaaa tcctcaacag gctgcagatt tttaccaaag
    13621 agcgctccca acaacctatt caattgcttc agccaagcag ctaaatggaa aagagctatc
    13681 attcaacaat attcgtgatg cagatgctgc gattcgtatt attcgtgatt ttaaggagcg
    13741 tccaaccgtt gtagcactca agcatatgaa tccatgtggt attggtcagg cagatgatat
    13801 tgagacagct tgggattttg cttatgcagc tgatccggtg tctatctttg gtggtattgt
    13861 tgtcctaaat cgtgaggtgg atctagcgac agcggagaag cttcatgcta tttttcttga
    13921 attgatcatt gcaccaggct attccaaaga agcgctagct gttctcaccc ataaaaagaa
    13981 gcacttgcga attcttgaat tgccatttgc tgctcaggag gctagtgaaa tagaagcaga
    14041 atatacagga gttcttggtg gtctactagt gcaaaatcaa gatgttgtca cagagtctcc
    14101 agcggattgg atagtggtga caaagcgtca gccaaatgaa caggaaatgg ctgctctagc
    14161 atttgcttgg aaaaccatca aatatgtcaa gtctaatgcg attgtcattg ctaatgatca
    14221 tatgactttg ggcgttggtc cagggcaaac aaaccgaata gcctctattc gtattgctat
    14281 tgcgcaagca acggggcagc ttgagggagc agttcttgct agcgatgcct tcttcccatt
    14341 tgcagacagc attgaagaaa ttgctgccgc tggtatcaag gctattatcc agcctggagg
    14401 ctctattcgt gattcagaat ctattgcagc tgccaatcag catggtataa ccatgatttt
    14461 cacaggtgtg aggcatttta gacattaata aagtaaaaag agactggagc caaaagagtt
    14521 gcactttaga aattcttggt taatatactt tattacctag ttggattcat taaaaagcga
    14581 acaagtctag ttttcataat ctcagaaaac tagacttgtt tgcttgtttt atttggtggt
    14641 catactattg tttcagcctc tttttactat gactaataca agaatttatg aaggaacaag
    14701 gctttatttt ttgttgtggt aacagtgacc agatccgtta tcaatcagta tttgagtatt
    14761 ttgagctcta gatgcatcac ttagatagga tattgcaaag gatacagctg ctgcatgtat
    14821 taggaaagca ttatcataaa aggctttttc gttagcctaa aggttttaga ccttctttgc
    14881 cttatctatt gttaaccatg ttccacgtga acccatttgc acgtaaatcc ccttgctagg
    14941 ctgatcaacc tttagaacct tataggttcc tgaaacgaca aaataatcac ccacctgcaa
    15001 aatctgattt ccagcaatac gtcctttatg gtccgtttcg tggagtggag ctgagtctat
    15061 ccagtttaag gaggttggct ctccaccggc taattcactg cttgcaatca tgttctgagc
    15121 gacctgatcg acccgaaaaa caccaggaaa ggctacagta tctccaacct tgataggagt
    15181 ggtcgccaca ggctttggtt tatctataga ggcttgacta tgttgctgag gctgaaccgg
    15241 caatttgtga attggaatgt agcgatgatt tcctgaatga ccgatatagc tgagccattc
    15301 atagccatca gcgacaaggg tttgatcata gtgcactaac tgtccagtat gatagtaagc
    15361 taaatcagga cttgctaatg tagcttcagc ctttatagga ctttggcttg aaaaataata
    15421 ggtaccactt ttagctagac gagttgatcc tgcttgagaa gcatgtaaca tttgtgtgtg
    15481 gctggtagag ttgtgatcca gatccttgaa gtgaatgtaa ccacttacct gatgcttatg
    15541 aatctgtcgt ttatgatact tttcaggtcc ctgtccggca ttatagttgt attcctcaat
    15601 aataacagtg tcaccattga cctctgctac ccaggcgacg tgtccatata gggcatgtga
    15661 ctggttaaag cccttatccc accaagcaac agcaccaact ctaggtgtat gatcaacatg
    15721 atagccttgg tgtttagcta tacgtcccca gctttcaaca ttaccatagc ctctaggcag
    15781 gctgaatcca tttgaggaat gcagtcggaa tgctacaaaa gaagtgcatt gacgtaagta
    15841 catgttccaa ggatcagctc cgaagccctg tttccactta cttggatagt tatcccctaa
    15901 aacagcagcg tgtacgatac ctgactgacc ttgtgaaatc gttgttgtgg cagaggatat
    15961 tgcaccatta ccacctaaaa ggattgctcc tgaagctaac aattgataga cttttttcat
    16021 taattacctc ctgtaactta ctattcgcaa gaaagaggac aaaaatgtcc ttgatttaaa
    16081 aaaatgtaag gaaaaatatt ttagcctcaa aatactgttg gtgctcccta gcttccaaga
    16141 gccaataggc aagcccatct ccagcttgcc tgctccctgt agctaaaagc aatttatagt
    16201 aacactagca cctcatctga agaggcaggc tgtggtaatt aatgccaata atctgtaaaa
    16261 agagacagca ggtatggtta tatgagctat gatggttata ttctataaag cttatttttt
    16321 agcttcgggc tttctttggt gattagttat ttatataaac gaacaattat gctaaaatat
    16381 gtttataaaa ttcgtgttat gaggtgtgtg atgaagcttt tagttatcgg ttcaggtggt
    16441 cgtgaacatg cgattgctaa gaaattgtta gagtcaaaag gcgttgaaca ggtttttgtg
    16501 gcacctggca atgatggcat gacccttgat ggcatagaac gggtagatat tgatatttcc
    16561 gaacattctg ctttgattgc ttttgcaaag accaatcata tagcctggac ctttgtggga
    16621 ccagatgacg cattagcggc tggtatcgtt gatgagttta accagtctgg cttgaaagcc
    16681 tttgggccct ctcgtttagc agcggagctg gagtggtcaa aggactttgc taagcaaatc
    16741 atggtcaaat acggtattcc aacagcagcc tatggcacat tttctgattt tgcaaaagcc
    16801 aaggcctaca tcgaggaaaa gggcgcgcca attgtggtta aagcagatgg tttggcgcta
    16861 ggaaagggtg ttgtcgtagc agagactgta gagcaggcag ttgaggcggc gcgtgacatg
    16921 ctcttggata ataaatttgg tgattcaggt gcgcgcgtgg tgattgagga atttttagct
    16981 ggtgaagagt tctctctctt tgcctttgtg aatggcgatc agttttacct catgccgaca
    17041 gcgcaggacc acaagcgggc tcttgatggt gacaaggggc caaatacagg tggtatgggg
    17101 gcttatgcac cagtgcctca tctttctcaa agtgtggtgg atacagcagt tgagaccatt
    17161 gtcaagcctg ttctaaaagg gatgatgaca gaggggcgtc cctatcttgg aatcctttac
    17221 tgtggcttga ttttgacaga agatggacca aaagtgattg aattcaatgc tcgctttggt
    17281 gatcctgaga ctcaggttat ccttcctcgc ctgacctctg attttgcaca gaacattacc
    17341 gatatattag agggcaacac agctaatatc acatggtcag acgagggagt gacgctcggc
    17401 gttgtccttg cttcaaacgg ttatccgctt gcttacaaga aaggtgtgct tctgccagca
    17461 aagaccactg gcgacatcat tacctactac gcaggggtta agcttgcgga aaatggcaaa
    17521 gcactgctgt caaatggtgg acgtgtctat atgctggtca ccacagcagt taccgtccca
    17581 gctgcgcaag aaaaaatcta taccgaactt gctcagcaaa ataccgaagg attattctac
    17641 cgaaacgata ttggaagaaa agcagtaaaa taaattagcg ctagctcaag ctaccgaagg
    17701 tcgctatgat gacaatgact tattatcggt gagcaaaagc gagcctaaca cgatactttt
    17761 cgccgtagcg caaagagtga caaggtcact cgggggaact tgaaagacct tgggctttca
    17821 agttagtcat gagacaccta tggtggctgt tgacgccccc ccacttaaga aaagtatcaa
    17881 aaacctttaa ggagaaagta tgaaaccaat tatctctatc atcatgggct ccaaatctga
    17941 ctggaccacc atgcaaaaaa ccgccgaaat cctcgaccag tttggccttg cctacgaaaa
    18001 aaaagtggtc tctgcccacc gcacgccgga tctcatgttc acatacgctg agaaagcacg
    18061 cgaacgtggc attaaaatca tcatcgctgg tgctggcgga gcagcccatc tccctggaat
    18121 ggtcgctgca aagacgacac ttcctgttat cggcgtacct gtcaaatcgc gtgctcttag
    18181 tggtcttgat tcgctgtatt caattgtgca gatgccaggt ggtgtgcctg tggcaactat
    18241 ggccattgga gaggcaggag caaccaatgc agcactgact gctcttcgga tcctttcaat
    18301 tgaggatgaa acaatcgcag agcagctcag ccatttccac aaagagcaag gacggatcgc
    18361 agaggagtca acccatgaac tcaactaaaa caattggaat tatcggaggt ggtcagctgg
    18421 gacagatgat ggcgatttct gccatttata tggggcataa ggtcattaca ctggatccag
    18481 cagcggattg cccagcctcg cgcgtgagtg aggttatcgt ggcgccttat agtgatgtgg
    18541 aggcgctgcg tcaattgacc gagcgctgtg atattttgac ctatgaattt gaaaatgtgg
    18601 acgctgacgc ccttgataca gtggtaaagg aggagcagct gcctcaagga acagagttac
    18661 ttcggatctc gcagaatcgt atttttgaaa aagatttttt agccaataaa gcaagcgcgg
    18721 cagtggcacc ctacaaggtt gtaacctcta gcctcgactt ggaaaacctt gacttttcga
    18781 aaaaatacgt cctcaagaca gcgacaggtg gctatgatgg acacggtcaa gtcgttattc
    18841 gctccgaagc agaccttgaa gaggctaata agttggctaa cactgccgag tgcgtcttgg
    18901 aagaatttgt cagctttgac cgagagattt ccgttattgt atctggcaat ggcacagatg
    18961 tcactgtctt tcctgttcag gaaaatatcc atcggaacaa tatcctgtca aaaaccattg
    19021 tcccagctcg catttcagaa gcagttagcg ctaaatcgca ggctatggcg gtgaaaatag
    19081 cagagcagct taacctatct ggcaccctct gtgtagaaat gtttgtggca ggcgacgaga
    19141 ttttggtcaa tgaaatcgcc ccacgtcccc acaactcagg acattactcc atcgaagcct
    19201 gtgatttctc ccagtttgac acccacattt taggtgtatt aggccagcca ttaccagctg
    19261 tcaaactcca tgccccagcc attatgctca acgtcctcgg ccagcacatg gaacaagccc
    19321 aacgctacgc cacagaaaac cctagcgccc acctccacct ctatggtaaa atagaagcca
    19381 agcacaaccg caaaatggga cacgtgacgg tgtttaacag tcaatcagat gaggttgaag
    19441 aattttagga ggaattaatc ctatgataaa aatcattgtt cacgctttta ttgaaaatgg
    19501 tgaaacaggt gttgttgaag ttgtctttgc ttcggaaaac caagaatcca tttctgaaaa
    19561 aatgacggag ctacaaaagc aatatccaaa cgattacctt gctatctatg atttaccact
    19621 agatacagac ctatcgcaat tggcccacta tccgtcaata gcgataggca aaggggagtt
    19681 tgagtagtta aggaagatta gtatttcgga ttgagtgtta ttgggacaat ttatggctat
    19741 gcctttcaaa agattggtca tgatgttgag catgttgtga gaattgagaa tcgtaatcag
    19801 atttcagaag ttggtaaatg acttaatgga taattctaga tactgatctc gagcaatcat
    19861 aagagaaatg ttgaaattgt agcttctgga ggtgtagaac tcaaaaatta tcgtggtgag
    19921 atatttccat ataaaacttc taagcgtatt tcgtctagat tgataacata tagataggtt
    19981 tgtacataat gaacttacta gatgcatcat gacaaagcag atcttttata tacatgcaaa
    20041 gaggtttaca atattggtat agtcaactat tgatgcccta acttttaatc acaatataga
    20101 aattattgcg aatagacttt aaaagcatta ctattaacta tgtagaaagg aaatgagcgc
    20161 tagaattttc aaactgaacc tgagcggaaa gctcggaatt tagataaatt tcctcggacg
    20221 taaatgtccg tctttagctt tctaaaattc agttgctttc tggctgttct tggtatctta
    20281 attatgctaa accgttattc acgccctgag atggcgaaga tttggagtga agagaacaag
    20341 taccgtgctt ggttggaggt ggaaatcctc gctgatgagg catgggctga gttgggtgag
    20401 attcccaagg aagatgtggc gaagattcgc gccaatgcga gttttgacat caatcgtatt
    20461 ttggagattg aagaagagac ccgtcacgat gtggtggcct ttactcgtgc ggtgtctgaa
    20521 acgctcggtg aggagcgcaa gtgggtccac tatggcttga catcgactga cgtggtggat
    20581 acggcctatg gctatctcta caagcaggct aatgacatta tccgtcgtga ccttgaaaac
    20641 tttaccaaca ttgtggctga gaaggctaag gagcacaaaa tgactatcat gatggggcgt
    20701 actcatggtg tgcacgcgga gccaacgacc ttcggtctca aattggcgac ctggtacagt
    20761 gaaatgaagc gtaatcaaga gcgttttgag catgcggctg ctggtgttga ggccggtaaa
    20821 atctcaggtg ctgttggaaa ctttgccaat atcccaccat ttgttgagga gtatgtctgt
    20881 ggcaagctag gcattcgccc gcaggaaatc tcaactcagg tcttgccacg agaccttcat
    20941 gccgagtact tcgcagtgct tgctagtatc gcgacatcaa ttgaacgcat ggcaactgaa
    21001 attcgaggcc tgcaaaaatc tgagcaacgt gaggtagaag agttctttgc caaaggacaa
    21061 aagggaagct ctgccatgcc tcataagcgt aacccgatcg gctctgaaaa catgacgggg
    21121 cttgcgcgtg tcattcgtgg gcacatggtg acagcctatg agaacgtggc gctttggcat
    21181 gagcgtgata tttcgcactc gtcagcagag cggattatca caccagacac gactatcctc
    21241 atcaactaca tgctcaaccg ttttggcaat atcgtcaaaa atttgacagt ctttccagaa
    21301 aacatgactc gtaacatgaa ctctaccttt ggcttgattt acagccaacg tgtgatgctt
    21361 aagctgatcg aaaaaggcat gacgcgtgag gaggcgtatg acttggtaca gccaaagaca
    21421 gcctattcat gggacaacca agtggacttc aagccgatcc ttgaggcaga cgaaaatatc
    21481 actgcaaaat taaggcaaga tgagcttgat gagctcttca atccagctta ttataccaag
    21541 cgtgtcgatg ctattttcga ccgattagga ttataggaag aaaacagcgc gtctttttag
    21601 actgtagcta agcccagatt tgtttaaaaa gtcttgaaaa tgaattcctc ggagctaatt
    21661 ctcaaaatga agaatagtat ttcaagagag gctgtcacta gctatatcgc ttaagaaaat
    21721 gctctaaaat agacattttt tcaatctgag aaggcaatag gccttctttt tttctaaaaa
    21781 tacagaaatg ttattataga atggagtcaa aaaattaata attaattaaa ttatgtgata
    21841 taatgaaaga aatagtgtct tgaagaggga aacatgttag acaattttgg tgaaaaggtg
    21901 agagaccttc ggtatcagaa aaaaattacc agagaggatt tatgtggaga tgagtcagaa
    21961 ttatccattc gtcaattggc acgaatagaa ctgggccaat cgattcccag cctatcaaag
    22021 gtggttttta ttgctaaggc tttggacgtt agtgtcggct ttttgacaga cggagaggat
    22081 ttggagctac cgaagcgcta taggagctta aatatttgat tttaagaaca ccgacctata
    22141 tggacgatga caaattaaag ctgcgagaag agcaatttga cgaaattttt gaagattatt
    22201 atgaccagtt gccagaggaa gaaaagcttg tggtggattg cttgcagtcc ataatggata
    22261 cgttattaac cgagaatatc aattttggag ttgggttatt acaggaatac tttgaacaaa
    22321 caaaaagtaa gactcaattt agagagaatg atctcattct tattgagctg tatttagcgt
    22381 acctcgacat tgcaggaatg aatggagagt attcagataa aggattctat gattctttgt
    22441 tagacatttt gttaaatcag tttgaacatt ttgaattaga ggaattattt attgtcaata
    22501 aaatagctat aggaatttcc tcgttgagca tcaaaaacaa taagccggag attcttgaga
    22561 aggttattgt acttagtcaa aaaattatcc tcaagactca ggattttaat agaatgccta
    22621 tcttaaattt gatagagtgg aaatatgctc taatgaagaa aaaagacata gaaatggcca
    22681 aaaaatgcta tgctaaggca tgcctgtttg ctcaattaac aggagatcag tatttggaaa
    22741 agaaattgag agaagaatgg ggtaaagata taaaacgata tcaataggac aaaaatgtca
    22801 tttttatcaa aaatggaata atatataatc tttatataac aaataattga ttaaaggagt
    22861 tccatttata tgtttaaaaa ataccaatac tatctgtttt tagctgcttt atttctactt
    22921 cattctgccc aattacttag tgatattgac tggtggcgtg ttggttaaag ctaaatcatc
    22981 tatttatgct ataatagctc tatgacaaga attttagata atgatctgat aggcgatgaa
    23041 ggatctgttg agaggacact acgtccacag tatttacgtg agtatattgg tcaggatagg
    23101 gttaaagacc agctgatgat ttttattgag gcagccaaga ggcgtgagga atccttggat
    23161 catgtcctgt tatttggttc cccaggcttg ggtaaaacaa cgatggcctt tgtcattgcc
    23221 aatgaattgg gagttcatct caagcagacc tctggcccag ccattgaaaa agctggtgat
    23281 ttggtggcaa ttttgaatga tttagagcca ggagatgtcc tctttattga tgaaattcat
    23341 cgtatgccga tggctgttga ggaaatcttg tacagtgcca tggaggattt ttacattgat
    23401 atcatgattg gcgctggaga cactagccgg agtgtgcatt tggagctgcc tccctttaca
    23461 ttaattggag caacgactcg tgcaggcatg ctgtcaaatc ctttgagggc tcgttttggg
    23521 attactgggc atatggaata ttatcagaca gctgatttaa cagagattgt ggagcgtaca
    23581 gctgatattt ttgacatgac aatcaagcat gaggccgctt atgaactggc acgcaggagt
    23641 cgtggaaccc ctcgtattgc taatcggctg ttaaaaaggg tgcgtgatta tgctcaaatt
    23701 atgggtgatg gaatgattac gactcaaatc acagataagg ctctaacgat gttagatgtg
    23761 gatcaagaag gtttagatta tgtggaccaa aagattcttc gtaccatgat tgaggtgtac
    23821 caaggagggc cggttggtct tgggactcta tctgtcaata tagcagagga gcgagataca
    23881 gtagaagaca tgtacgagcc ttatttaatt caaaagggtt ttatcatgcg taccagaaca
    23941 ggccgagttg tcaccgaaaa agcctatcag cacttaggct atccctatga aaaaaccatt
    24001 aagacataaa tagctatgta agacttgatt cctttgtttt taccggtgtc aagtcttttg
    24061 tattgtcaat agcttactga gtaaaaaagt aaaacgatgt gaggtgaggg gtgattggtc
    24121 agggaagcag aggtgctttc actagacaaa gcattaaaaa acatttttag atcaattgaa
    24181 cgaaaattat aagagcgatt tctccttttg gccctataat tttgctataa taggtaaaag
    24241 gagtttttca tgaaaaaagt atgctttgtt tgtcttggaa atatttgtcg tagtcctatg
    24301 gccgaatttg tcatgaaaag tatggccagt cctgatgagc tacaggtgga gagtcgtgca
    24361 acctctggct gggagcatgg caatccaatt catcatggga cacaatcgct attacagcaa
    24421 tatcagatta gctatgatac caagaaaacc tctcagcaaa tcaccagctt tgactttgaa
    24481 gcctttgact atattatcgg aatggatagc cataatatca gagatttgaa gcaaatgtcc
    24541 aagcatcagt gggattccaa gatccatctt tttattgaag gaggcgttcc ggatccttgg
    24601 tatacaggag attttgaaga aacctaccgc ttggttaaag cgggctgtca gcattggttg
    24661 agtcaaatca gcgctgaaca tgaatcacat gtggaaatag atgagtaata gtaatgaaag
    24721 caataataaa taacattcaa aaatggcaga tcactcggac aaagctagag attatttcag
    24781 tccttgtgat tattgtctgt ggattgtcgg tttttacctt gaccatatcc tcaaaagcaa
    24841 gcttgaccta tgacaatggg caaatcaagt acaccggcta tgtccttaat catagaatga
    24901 atggtaaagg gaaattggtt taccctaatg gcgataccta tgttggggat tttaataaag
    24961 gtgtctttga tggagaagga acgtttacag ctagtacagg gtggtcttac agcggacaat
    25021 ttaaaaaagg tcaggctgat ggcaagggta ctttgaaggc gaaggattca aaggtttaca
    25081 aaggaacctt taagcagggg atatttcaaa aatgaggata aaatggtttt cgtttattag
    25141 ggtaacaggt cttttgctgg tgttgctcta tcactttttt aagcatactt tttcaggagg
    25201 ctttgttggc gttgacatct tctttacttt ttcaggctat ttgattacag ccttgttgat
    25261 tgatgaatat gtctcaaaac aaaccattga tgtggttgct ttttttagaa ggcgttttta
    25321 tcgtattgta ccgccgcttg tcttgttaat tctcttgaca attcccttta cttttttagt
    25381 caaaagtgac ttcattgctg gtatcggtca gcaaatagca gctgccctag ggtttacaac
    25441 aaatagttat gagctactga caggcagtag ctatgaaagt caattcattc cgcatctgtt
    25501 tgtgcatacc tggagcttgg ccattgaggt gcatttttat ttgctttggg ggctgttggt
    25561 ttggttatta gctaaaaaag gctacagtca gaagaaattt agaggcattc tgtttttaat
    25621 ttcttccgca gtgttcacgc ttagctactt cagcatgttt atcagagcct tctttgtatc
    25681 agatttttct tctgtttact tttcaacgct ttcacacagc tttcctttct ttttaggagc
    25741 gatgtttgca accatgacgg gaattaagga cacgactgtt cgctttcaaa agaatgttaa
    25801 gctgtggcca aggctacatg ttattggagt gatggctggc gcttttgctc tgttgttgtt
    25861 tctaacgctt gtgttagatt ttaaccatat ctttacctat cttttcggtt ttgtcttagc
    25921 cagtcttttt gcttcggtaa tgatttatgc tgcgcgtgtt ttgagcgatc aaacaccaac
    25981 ctggcaggaa ccactgcttg tgacctatct tgcggatatt agctatggga tttatttatt
    26041 ccattggcca ttttacatta tttttacaca gctgatgtct aactggctgg cagtgatctt
    26101 aacggttttc ttttcagtag tgttttcaac gctttcttat tacattattg agcctttgat
    26161 tcaaggcaag acaccacagc tttttggttt agcaattgat tgtaatccct ataagaaatg
    26221 gttatcaggg cttgctttag gactcttttt gttgatggtt ggtacctgtt tgacagcacc
    26281 aagggtcggt aattttgaga cccagctttt agtagattcc ttgcagcaat ctcaaagtaa
    26341 tctcaataag acacatactt tggcagcagg agatgcgcat gctcttagtg atgttagcat
    26401 tattggtgac tcagttgcct tgaggtctag tgacgctttt tcaaaattaa tgccgactgc
    26461 tcaactagac gctgctgtca gccgcaattt cagtgaagcc tttgagcttt ttgaaaatca
    26521 tatccaatcc aagagcttat caaaaacaac ggttttagct gttggtgtta attctcttta
    26581 taattatgcg caggatattc aaggctttat ttatgcacta ccaaaggggc atcgcttggt
    26641 gattgtgtcg ccctatgatg ctaagaatgc agcacaggta gcagaggcta gagagcattt
    26701 gttgcagcta gctaaaaaat atagctatgt aacagttgct gactggtaca aggcggcagt
    26761 cgaaaatccc aatatctggt atggtagtga tggggtccac tacaataacg acgccaaatt
    26821 aaaaggtgct gacttatatg tctcaacgat tcaggcggct gttgagcgag cagcaaaaaa
    26881 agatgctaaa tagtggtgct aacaacaatt tgttaagaat taataacgaa ggcttggtct
    26941 tacaaacaga tcaagccttt tcatgatgtg atttttagat cgtcttgcgc cctttagcgc
    27001 gagataaagc tccacctgtt agacagtgtc attattggct gttattgctg acggtgacgt
    27061 gcttttaaaa acggatcatt aaataattta gcctgatcta aaaaagaaag cgctttcgga
    27121 acaaagtgaa tgcgtcagcc attatttcag aaaaaatcca ccaagccaaa ccccttgtta
    27181 tcaaagagtt tcggaaattg attgaaaaaa catcacaatt ttattgtgaa atgatttaca
    27241 aaatgccaaa aaatgatata atatttttgt aaacaaaatt gtgaaacttt taacaaggta
    27301 aaggagtctc aaatgactga aaaaaatagt actgttgaaa caacatctgt tgccgcaaca
    27361 attgacgctc ttgttcaaaa aggtttagta gcgcttgata aaatgcgtca gttaactcaa
    27421 gaacaggttg actacattgt agcgaaggcc tctgttgctg ctttggacgc acatggtgag
    27481 ttagctaagc atgcctatga agaaactggt cgcggagttt ttgaagataa ggctaccaaa
    27541 aaccttttcg catgtgagca cgttgttaat aacatgcgtc accaaaaaac agtaggtatc
    27601 attgaagaag acgatgtaac aggtttgacc ttaattgctg agccagtagg tgttatttgt
    27661 gggattaccc caacaactaa cccaacgtca acagctattt ttaaatcttt aatctcctta
    27721 aaaacacgta accctattat ttttgccttc cacccatcag ctcaagaatc atcagctcat
    27781 gcagcacgca ttgttcgtga tgcagccatt gcagcaggag ctcctgagga ctgtgttcaa
    27841 tggattgaaa ccccatcact agaagcaact aacgctctga tgaatcatga tggtattgca
    27901 acaatccttg caactggtgg taatgctatg gttaaggcag cctactcatg tggtaagcca
    27961 gctcttgggg ttggtgctgg taacgtgcct gcctatgttg aaaaatccgc taacattcgt
    28021 caggcagcac acgatattgt catgtctaaa tcatttgaca atggtatggt ttgtgcttct
    28081 gagcaggctg ttattatcga caaggagatt tatgacgagt ttgttagtga atttaagtct
    28141 taccacactt actttgtcaa caaaaaggaa aaggctctgt tagaggaatt ctgctttggt
    28201 gctaaggcta acagtaaaaa ctgtgcaggt gctaagctga accctaatat tgttggtaag
    28261 ccagcagctt ggattgctga gcaggcaggc tttacagtac cagaaggaac gaatatcctt
    28321 gcagcagaat gtaaggaagt ttctgaaaat gagccattaa cacgtgaaaa attgtcacca
    28381 gttatcgctg ttttgaaggc tgaatctcgc acagatggtg ttgaaaaggc tcgtcaaatg
    28441 gttgaattta acggacttgg tcactcagcc gctattcata ctgctgatgc agacttagct
    28501 aaggaatttg gaacaaaaat tcgtgctatt cgtgtgattt ggaattcacc ttctacattt
    28561 ggtggtatcg gtgatgttta taatgccttc ctaccgtcat taacattggg ctgtggttct
    28621 tatggacgta actcagttgg tgataatgtt agtgctgtaa atctcttgaa catcaaaaaa
    28681 gtaggaagac gtagaaataa tatgcaatgg tttaaagttc cttcaaaaac atacttcgag
    28741 cgtgattcaa ttcaatacct tcaaaaatgt cgtgacgttg agcgtgtgat gattgttacc
    28801 gaccacgcta tggttgagct tggcttctta gatcgtatca tcgagcagct tgaccttcgt
    28861 cgtaataagg ttgtttatca aatttttgca gatgttgagc cagatcctga tatcacaacg
    28921 gttatgaaag gtactgagct gatgcgtacc tttaagccag atacgattat cgctcttggc
    28981 ggtggttctc caatggacgc tgcaaaggta atgtggttat tctatgagca accagaggtt
    29041 gacttccatg atcttgttca aaaattcatg gatattcgta aacgtgcctt caagttccct
    29101 gagcttggta agaaaacaaa atttgtggct attccaacaa cctcaggtac aggatcagag
    29161 gttacaccgt ttgctgttat ctcagataag gccaacaacc gcaagtaccc aattgctgac
    29221 tattcattga caccaacggt agccattgtt gacccggcgt tggtgcttac agtaccaggc
    29281 ttcattgcag ctgatacagg tatggacgtg ttgacccacg caaccgaggc ttacgtatca
    29341 caaatggcta atgactttac agatggtttg gcccttcaag ccattaagat tgtctttgaa
    29401 aaccttgaaa aatctgttaa ggaagctgac tttgagtcac gtgaaaaaat gcataatgcc
    29461 tcaacaatgg caggtatggc ctttgctaat gccttcctgg gtatttctca ctcaatggct
    29521 cataagattg gtgcacaatt ccatactgtt catggacgta ccaatgctat cttgcttcca
    29581 tacgttattc gttacaatgg tacccgtcct gctaaaacag caacatggcc taagtacaat
    29641 tactatcgcg ccgatgaaaa atatcaagac attgctaagt tgctaggact tccggcatct
    29701 actccagaag aaggtgttga atcttatgct aaagctgttt atgatcttgg ctgtcgctta
    29761 ggcattaaga tgaatttcag agatcaagga attgatgagg aagaatggaa ggcacacact
    29821 cgtgagcttg cttatcttgc ctacgaggat caatgctcac ctgctaaccc acgcttgcca
    29881 atggttgagc acatggaaga aatcatgaat gatgcttatt atggttacgc agagcgtcca
    29941 ggacgtcgga aataatatca atcattaata gtaaaaatag gagctgcttg gcttctattt
    30001 ttttatctag ctatgaaaag ggctgtgtta gatgaaaaag tcggcagtgc cttgtgttga
    30061 gatagcttaa ctcaggggta gtttctcaga tatcatataa agcttttaag acaatggttt
    30121 tacagagcat tccatcagag ggggaagctt catttgccat attcataaag tggctgatag
    30181 ttacgactta gctgcactta gcaattagct gaagaaaata acatgttgcg tctatctgat
    30241 gagctttatt ttctaataaa acaaggagtg attgcttttt taatgatgtt aatagcgtta
    30301 aaaaccttta tatatcaaac aaaaaccaaa ataatggtat tgtcagactt tttctaaaat
    30361 taccctttat taattgacaa agagggtgta aaaaattata ctaaaaatgt aatcgattac
    30421 attttctaga ctaaatttgg agacgtttta tgaaagcagc tacatatgtt gctccaggtc
    30481 agctggagct tattgatcaa ccaaaaccag agattcttgc tccgacagat gctgtggttc
    30541 gtttattgaa aacaacaatc tgtggaacag acttacatat tttaggtgga gatgtcccag
    30601 agactactca tggtaccatt ttaggtcatg aaggtattgg tattgtcgag tcagtcggct
    30661 ctgcagtgaa caactttaag gtaggtgata aggttattat ttcctgtatc acagcctgta
    30721 atacctgcta ttattgtaaa aaaggaattc ctgctcattg tgaaagcggt ggctggattc
    30781 tagggcattt gattaatggg acacaagcag agtatgttca tattcctcaa gcagatggca
    30841 gtctttatca tgctcctaaa accgttgagg atgatgcctt ggttatgctg tcagacattt
    30901 tcccaacttc ctatgaaata ggcgttcagt ctgcaaaggt aaagccgggt gatacagtgt
    30961 gtatcgttgg agcaggtcct atcggactag cagctctttt aacagcacaa ttttattcac
    31021 cagctaagct gatcatggtt gacttgtcag aatcacgttt agaagcagct aagcgctttg
    31081 gagcaacaga tacgatttgc tctggtgacc ttgatgatat tgtcaaaaaa gtccatgaat
    31141 taactgatgg tcgaggtgtt gatgttgcca ttgagtgtgt aggctatcct gctacctttg
    31201 atatttgcca aaagattatt gctattggcg ggcatgtttc taacgttggt gtccatggaa
    31261 aaccagttag tttggaccta caggacctat ggatcaaaaa cattacaatg tcaactggcc
    31321 tagtaaacgc taatacaaca gaaatgctat tgaatgtgtt gaaatctggt aagattgatg
    31381 caactaagat ggtaacacat cactttaagc tgtcagaggt tgaaaaagcc tatgaggtct
    31441 ttaaaaatgc cggcagtaat aacgccctta aagtgattat tgaaaatgac attacagcct
    31501 aaaggaataa ggtataaata gataaaagtg acaacagcat ttggaatggt ctagatgctg
    31561 ttttttagcc aacttaactg gttaagttta ttttcagaaa actttcaaga aattggttga
    31621 caaaccttgt gaaaaagtat acaatacaaa ttgtaaacgg ttgcaaaaat agataaaccg
    31681 agacttagaa attggaggca tcctatgaag gctgtagttg ttaaccaaac cagcagtggt
    31741 gtagaggttg tagagcatga tgtaccatca atcggtcatg gagaagctct tgttaaagta
    31801 gaatattgtg gcgtatgtca tactgacttg catgttgcgc atggtgattt tggtcaggtt
    31861 ccagggcgta tcctcggtca tgaaggtatc ggtattgtcg aaaagctagg tgaaggcgtt
    31921 acctccttaa aggttggtga tcgtgtatca attgcttggt tctttgaagg ctgcggtcat
    31981 tgtgaatatt gtacaacagg tcgcgagact ctatgccgtt cagtcaaaaa tgctggctat
    32041 tcagttgatg gtgggatgag tgagtatgca gttgttacag ctgactatgc tgtgaaagtg
    32101 ccagatggtc ttgacccagc tcaagcatca tcaattacct gtgcaggcgt tacaacctat
    32161 aaggctatca aagaagcagg tgccgctcca ggacaatgga ttgttatctt tggtgccggt
    32221 ggacttggta acctagctgt tcagtatgct aaaaaggttt tcaatgctca tgtcgtagca
    32281 gtggacatta acaatgataa gctagagctg gccaaggagg ttggagcaga tatcgttgtc
    32341 aatggtaaag aaatcgaaga tgttgccggc tatatccaag aaaaaacagg tggtgctcat
    32401 ggcgttgtgg taaccgctgt ttctaaagta gcctttaacc aagctattga tagtgtgcgt
    32461 gcaggaggaa ctgttgttgc tgtaggactt ccatcagaat acatggaatt atctatcgta
    32521 aagactgtcc tagacggaat caaggtagtc ggatcacttg tgggaactcg taaagacttg
    32581 gaagaagcct ttgcctttgg tgcagaaggt ctggttgtgc cagttgtaga aaaggttcca
    32641 gttgagactg ctccagaagt ctttgacgaa atggaacgtg gtctcattca aggaagaaag
    32701 gtattggatt tcacgcttta aggctgattt cagaaaaagt cagcagccag acaagctgat
    32761 tgtcccaaat gatgaataaa gtccttagaa ttaattttct aagggctttt ttggtgaaac
    32821 taactggtaa aaaaagcttg gtatctaaag atgtaaaaga gccagctagt tattaatacc
    32881 atgattgccc cttgaaagac agtaccagag aaagttggac atattgtaac ctctgataga
    32941 gatactgggt ttgaacaata ttagagatta acacaggaac tcaatctaga agtttatttc
    33001 tctgctcctc acaccccttg ataacgtagg acaaatgaaa ataccaatgg gttaatcaaa
    33061 gagtagtttc ctaaaggaac tgacttgact gatattgaga gctctatcat ataagagtgg
    33121 gaagataaat gaaatgatcg ttctagaaga tgtcctaact ggaaactacc ttataaactc
    33181 ttttatggaa aagcgttgca cttaatttga caattcgtct tcacaaattt taggaagcac
    33241 tgtaggaaaa aagaataatg acataacata ttgctaaaaa catgggttat aagctaaatt
    33301 at
//
LOCUS       DARYLD010000017        31752 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYLD010000017 DARYLD010000000
VERSION     DARYLD010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31752
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..1435)
                     /locus_tag="TU651_000703"
     CDS             complement(<1..1435)
                     /locus_tag="TU651_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL0896723.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU651_000704"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TU651_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL0896724.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU651_000705"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TU651_000705"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL0896725.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU651_000706"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TU651_000706"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL0896726.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TU651_000707"
     CDS             complement(5344..6630)
                     /locus_tag="TU651_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL0896727.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TU651_000708"
     CDS             complement(6772..7143)
                     /locus_tag="TU651_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL0896728.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TU651_000709"
     CDS             complement(7130..7402)
                     /locus_tag="TU651_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL0896729.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TU651_000710"
     CDS             complement(7433..8944)
                     /locus_tag="TU651_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL0896730.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU651_000711"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TU651_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL0896731.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TU651_000712"
     CDS             complement(12410..12979)
                     /locus_tag="TU651_000712"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0896732.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU651_000713"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TU651_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL0896733.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TU651_000714"
     CDS             complement(14337..14702)
                     /locus_tag="TU651_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0896734.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TU651_000715"
     CDS             complement(14823..15020)
                     /locus_tag="TU651_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL0896735.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU651_000716"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TU651_000716"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL0896736.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU651_000717"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TU651_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL0896737.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TU651_000718"
     CDS             complement(17976..18749)
                     /locus_tag="TU651_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL0896738.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TU651_000719"
     CDS             complement(18869..20092)
                     /locus_tag="TU651_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL0896739.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TU651_000720"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TU651_000720"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL0896740.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TU651_000721"
     tRNA            complement(21081..21154)
                     /locus_tag="TU651_000721"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TU651_000722"
     tRNA            21435..21506
                     /locus_tag="TU651_000722"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TU651_000723"
     tRNA            21539..21612
                     /locus_tag="TU651_000723"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TU651_000724"
     CDS             complement(21873..24458)
                     /locus_tag="TU651_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL0896741.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TU651_000725"
     CDS             complement(24581..26200)
                     /locus_tag="TU651_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0896742.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TU651_000726"
     CDS             complement(26280..27152)
                     /locus_tag="TU651_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0896743.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TU651_000727"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TU651_000727"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL0896744.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TU651_000728"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TU651_000728"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL0896745.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30654..31046
                     /locus_tag="TU651_000729"
     CDS             30654..31046
                     /locus_tag="TU651_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0896746.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31121..31522
                     /locus_tag="TU651_000730"
     CDS             31121..31522
                     /locus_tag="TU651_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0896747.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31519..>31752
                     /locus_tag="TU651_000731"
     CDS             31519..>31752
                     /locus_tag="TU651_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0896748.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDST"
BASE COUNT         9884 a         6364 c         5841 g         9663 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga aatatagaaa
    30541 tcatgttaaa ataatattat taaatagtta aattaaaaag aaatatacca aaatgattcc
    30601 atttattttt gggaatttat cgataagtat aggaatgata taggagtata gacatgaata
    30661 ggtttttaaa gatcagtctg cttattgttg gtgttattgt cattatgctt ggcatggaag
    30721 taaagcatag aatggatata tacgatcaaa tcaagcagga ggagataaaa attgcccaaa
    30781 gtaaagaagc aattgtgatt tatgaacagg agttaaaatg gttggaccca aatgcattga
    30841 caaatgaagg gactattaaa tcctattcta ttgatttaga ctcaataact cttaatccaa
    30901 tgggaggctt ttccattgct ttacatataa acaaaaatcc aaagtataag tatcgaataa
    30961 gtttaatgtg gaatacacca atgagagatt tatgtgtggg aggatcctct ttgtcgccag
    31021 aattacaaga attgttagat aggtaatgat tatgacaggc tatcagaaac aattgattgc
    31081 accaaagaac aatataattt tcatgaaaag gagcatagtt atgaaaacat tgttaaaact
    31141 cattgtattt attgttggta ctcttgtact tatgcttggc atggaggtaa agcatagaat
    31201 ggatacatac gatcaaatca aacaggtaga gctcaaaaac gcgcatagta aagaagtgat
    31261 tgaaatgtat gaacaggagc taatatcaat ggatccccag gccctaacag atgaaggact
    31321 tatcaagtcc tacactatcg actcagattc actctttatt aatccgatgg gaggcttttc
    31381 cattcattta attatcaatg atgatccaga tatttacttg agagttggcc ttggtagata
    31441 tgatatggaa agaaatttgg agattgatgg tatctatcgc tcagaaaagt tagaaaaact
    31501 actaaaagga gtggagagat gaaaacattg ttaaaactta ttgtatttat tgttggtgcc
    31561 cttgtactta ttcttggcat ggaggtaaag catagaatgg atatatacga tcaagtcaaa
    31621 caggtagaac tcaaaaacgc gcatagtaaa gaagcgatag acatttatga aaagaagtta
    31681 aaaagattgg atcctcaggc cctaacagat gaagggctta tcaagtctta tactattgac
    31741 tcagactcaa ct
//
LOCUS       DARYLD010000018        31534 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYLD010000018 DARYLD010000000
VERSION     DARYLD010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31534
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..316
                     /locus_tag="TU651_000732"
     CDS             <1..316
                     /locus_tag="TU651_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0896749.1"
                     /translation="PKPEPKPEPKPGPKPGPKPGPKPEPKPGPKPEPKPEPKPEPKPE
                     PKPEAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIAAGTIAIPKRKE
                     ED"
     gene            complement(562..876)
                     /gene="trxA"
                     /locus_tag="TU651_000733"
     CDS             complement(562..876)
                     /gene="trxA"
                     /locus_tag="TU651_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL0896750.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            1056..2375
                     /locus_tag="TU651_000734"
     CDS             1056..2375
                     /locus_tag="TU651_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL0896751.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2715..5051)
                     /locus_tag="TU651_000735"
     CDS             complement(2715..5051)
                     /locus_tag="TU651_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL0896752.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(5124..5669)
                     /locus_tag="TU651_000736"
     CDS             complement(5124..5669)
                     /locus_tag="TU651_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL0896753.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5669..5980)
                     /locus_tag="TU651_000737"
     CDS             complement(5669..5980)
                     /locus_tag="TU651_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896754.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            6098..7006
                     /locus_tag="TU651_000738"
     CDS             6098..7006
                     /locus_tag="TU651_000738"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL0896755.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            7031..7630
                     /gene="lepB"
                     /locus_tag="TU651_000739"
     CDS             7031..7630
                     /gene="lepB"
                     /locus_tag="TU651_000739"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0896756.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7859..10258
                     /locus_tag="TU651_000740"
     CDS             7859..10258
                     /locus_tag="TU651_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL0896757.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10354..10839
                     /locus_tag="TU651_000741"
     CDS             10354..10839
                     /locus_tag="TU651_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896758.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10982..12085)
                     /gene="dinB"
                     /locus_tag="TU651_000742"
     CDS             complement(10982..12085)
                     /gene="dinB"
                     /locus_tag="TU651_000742"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL0896759.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12294..14618
                     /gene="pflB"
                     /locus_tag="TU651_000743"
     CDS             12294..14618
                     /gene="pflB"
                     /locus_tag="TU651_000743"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL0896760.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14924..15202
                     /locus_tag="TU651_000744"
     CDS             14924..15202
                     /locus_tag="TU651_000744"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896761.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15366..16307)
                     /locus_tag="TU651_000745"
     CDS             complement(15366..16307)
                     /locus_tag="TU651_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL0896762.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16304..17059)
                     /locus_tag="TU651_000746"
     CDS             complement(16304..17059)
                     /locus_tag="TU651_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL0896763.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17552..18400)
                     /locus_tag="TU651_000747"
     CDS             complement(17552..18400)
                     /locus_tag="TU651_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL0896764.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKSSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18502..18954)
                     /locus_tag="TU651_000748"
     CDS             complement(18502..18954)
                     /locus_tag="TU651_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL0896765.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18974..20173)
                     /locus_tag="TU651_000749"
     CDS             complement(18974..20173)
                     /locus_tag="TU651_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0896766.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20342..21001
                     /locus_tag="TU651_000750"
     CDS             20342..21001
                     /locus_tag="TU651_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL0896767.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            21022..23307
                     /locus_tag="TU651_000751"
     CDS             21022..23307
                     /locus_tag="TU651_000751"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL0896768.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23413..23805)
                     /locus_tag="TU651_000752"
     CDS             complement(23413..23805)
                     /locus_tag="TU651_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL0896769.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23959..24216)
                     /locus_tag="TU651_000753"
     CDS             complement(23959..24216)
                     /locus_tag="TU651_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0896770.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24395..24769
                     /locus_tag="TU651_000754"
                     /pseudo
     CDS             24395..24769
                     /locus_tag="TU651_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(25027..25809)
                     /locus_tag="TU651_000755"
                     /pseudo
     CDS             complement(25027..25809)
                     /locus_tag="TU651_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26326..27834)
                     /locus_tag="TU651_000756"
     CDS             complement(26326..27834)
                     /locus_tag="TU651_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0896771.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            28085..28981
                     /locus_tag="TU651_000757"
     CDS             28085..28981
                     /locus_tag="TU651_000757"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0896772.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28978..29241
                     /locus_tag="TU651_000758"
     CDS             28978..29241
                     /locus_tag="TU651_000758"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL0896773.1"
                     /translation="MKGEAGAPDTPQKPNDPLQSLEGGNSPIVEQNYGSTEGYHGQSG
                     ILEETEDTNPPGIILGGSGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29168..29974
                     /locus_tag="TU651_000759"
     CDS             29168..29974
                     /locus_tag="TU651_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL0896774.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30346..31392)
                     /locus_tag="TU651_000760"
     CDS             complement(30346..31392)
                     /locus_tag="TU651_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0896775.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31394..>31534)
                     /locus_tag="TU651_000761"
     CDS             complement(31394..>31534)
                     /locus_tag="TU651_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL0896776.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9423 a         7431 c         6294 g         8386 t
ORIGIN      
        1 gcctaagcca gagcctaagc cagagcctaa gccagggcct aagccagggc ctaagccagg
       61 gcctaagcca gagcctaagc cagggcctaa gccagagcct aagccagagc ctaagccaga
      121 gcctaagcca gagcctaagc ctgaagctaa gaagcctgaa caacctaaac caatgactaa
      181 accaggagct aagaagcctg agcaatcact tccatcaact ggtgacatca gaaatccatt
      241 cttcacgcct gcagctattg ctattatgat cgcagcaggt accattgcca ttccaaaacg
      301 caaggaagaa gattaaacaa attaacaatc cccatatttc aacaatgata cacaagcccc
      361 tacttgtgtc cacctcaaaa gcagtagcca gtcgcgcggc tactgctttt actatgcttt
      421 ttttacacca gctctgatag cagctaataa caaaaaagat tgaagacaca gcttattggg
      481 tccccgatct ttttttggtc atacaaccaa cagcagctct tgaggcttgc tgtccttcta
      541 agaggctgtt ggcttgttgc tttagcttaa ttctgctacg atagccttga tttgatcctt
      601 ggtatggacg cctgctactt gcttgacaac cttaccgtcc tttttgaaca gcagggttgg
      661 gatagacata atgccaaatt gttgagcagt attggggttg tcatcaacat ctagcttgac
      721 aatcttaagc tcagcttcgt caatttctgc tgctaattga tcaaggattg gcgcttgcat
      781 taagcaaggg ccgcaccagg ttgcccaaaa gtccacaagg actaggcctt cattagtttc
      841 tgcttcaaat gttgcatctg ttacgatatg tgccattgta atctccgttc ttatagttta
      901 taagcctatt ttaggggaaa acgactgata atgcaagaat ctgatacgaa gacctcggtc
      961 ttatgattta agaaaaatct ggcgtagcca ttttaagaca aatacgctgg cctttgctac
     1021 aatgacctta tcttaacaac taaaaggagg ctactatgga agcatacgag cttattgtga
     1081 ttggatttgg taaggccgga aaaactttgg ctgccaaaat ggcgcagcta ggaaaaagag
     1141 ttgcccttat tgagcagagc cccactatgt atggcgggac ttgtatcaat atcggctgta
     1201 ttccaacaaa ggccttaatc actgctgctg agcataatgc tagctttgca gacgctatgg
     1261 cgcacaaaga tactgttgtt catcgtcttc gccaaaaaaa tgagcagctg ctagctcagt
     1321 ctggtgtgac actttacaac ggtaaggcaa gctttgtctc taataagacg attcaagtag
     1381 aagcagggca ggagcggatc ctcttagagg gcaagcatat cgtgatcaat accggagctg
     1441 tttcaaatcg ctttccgata cctggtctag cagatagtca gcatgtggtt gatagtacag
     1501 ggattctagc tctcactgag cagcctcagc gcttggctat tatcggtgcg gggaatatcg
     1561 ggctagaggt tgccagcctt tatgccagct taggcagcga ggttactatg tatgaggctg
     1621 cacctgctat tttagggcgc tatgagccgg ttgtcgctga gctggcacag gattacctgg
     1681 aaaaagctgg ggttaccttt aagctctctg cgactgttga gctgattgct aatgatgaag
     1741 caggtagagt tctagtgact gctaatggca agacagaagc ctttgattgt ctcctctatg
     1801 ctatgggacg taagcctgcc actcaaggcc ttggcttgga aaacactgac attaagcttg
     1861 atgatcgcta tgctgtcgtg gtagatgatt attgtcaaac cactgtcgag gggctatatg
     1921 cggttggtga tgttaatggc gggcctcaat ttacctatac gtccttagat gatttcagga
     1981 ttgtgtttgg gcagctaaca ggcacaagcc agtacaacca caaagatcgg ggctatctgc
     2041 caacaacagt ctttatcgag ccgccacttt cacaaattgg tctaacagaa aaagaagcaa
     2101 aagagcaggg actgccctac aaggctaatg agctcttggt tgccaatatg ccacgcgccc
     2161 atgtcaataa cgacctcagg gggattttta aggtcattgt caatacagag actaatgaaa
     2221 ttctaggggc aaccttattt gctaacaatt ctcacgaata cattaacctg attaagatgg
     2281 ctatggataa ccagattcca tatacctatc tcaaaaacca gctctttacc cacccgtcaa
     2341 tggctgaaaa tcttaatgat gtctttaacc tttaaaagaa cctcaacctc acctgcatag
     2401 caggtacaac agccaaacta ttaaaaaaac aaactccttt ttggctgctt atcacatgga
     2461 taggcggcta gcaaaaggag cttgtttttt cttgtatcca atcagcaggc tagcagctgc
     2521 tcatggtcta aaggaactag ctaggctggg acacgttggt agcaaaagtc cagcaagact
     2581 cactagctgc tgtcatgagc tttgaagagc agcacttagg gaacacgccc agtagctttc
     2641 tttgggacgc ttggctcacc tagggctcaa tcagcttgag taaaaagggg ctttatttga
     2701 atcaagagga tcaattagcc tagattagct atggtacagc ctgagccgcc agcattttgc
     2761 ggggcatagc caaagctttt gacatgcttg ttgcgtcgca agtacttgcc gaccgcttca
     2821 cgtataacac ctgtaccaat accatgtatg atgtcaacct gactcatgtt gttaagcaag
     2881 gcttggtcga taaaggcatc tagctcctgc atggcctcct catagcgctt gcctcgaagg
     2941 tctaagcgag cgcgcggccc ttttcctgta gctgcttttt tgacgacctt gacagctctc
     3001 ttcttaggct gctgcgcttc ttcttttagc ttaaccaagc tgaattcgtc ttccttgagg
     3061 gtcaacttga tcaggccaac ctgagcctcc cacctcttgt ccttaagctg ggcaagcaag
     3121 gttcctcttt gcccataggc ggtaacaatg atgtcatcac ccacacgagg agcccgccat
     3181 tttttcgctt ttttcagcac cttattttgc gacaggcttt gctctggcgc aagctgcttt
     3241 aggcgatgct tggcttcgat aatttcgtgc ggctttagct ctgccttttc atgcagctga
     3301 cttaaaatgc tatcactttc tgccaaggct atatccacaa tctcacgcgc ttcaagggct
     3361 gccttttcca attccttgtc cttagcgtgg gagaactcgt tatagagctt tttaacagca
     3421 cgattgaatt tgaggttatc ctgctcgacc tccttgatat gctcaaggcg cttgcggctt
     3481 tctaacgttt gctgctctag ttgctcaatg atacgattga catcatgatc agttgcggtc
     3541 atcgcctgag cttccttgac gatgtgctct gctaagccca atcgtctcgc aatgtcaaaa
     3601 gcatttgagc gaccaggcac tccttgcatg aagcggtaag taggctttag gctgacattg
     3661 tcaaaggcca tgctggcatt ttcaacatag gctgtctcaa tcccataggc ctttagctct
     3721 gggtaatggg tagtggccat cgtcttaata ttggtcagac gcagctgctc caaaatagcc
     3781 atagcaaggc tggctccttc ctgtggatca gtccctgctc ctagctcgtc aaagaggatc
     3841 aagctgtcac tgtctgcctg attgagaatc tcaacaatgt gagtcatatg actggaaaag
     3901 gtagacaggc tttgctcaat ggattgctca tctccaatat cagcataaat accattaaaa
     3961 actgccaccc tggagccctt gtcagccaaa ataggcagcc ctgactgggc catcacctga
     4021 gcaagcccca aggttttgag catgatggtc ttaccacctg tattaggacc ggtgatcaca
     4081 attactgcta agtcatttgc aaaatgcaga tcatttgcca cagggttttg aatcaagggg
     4141 tggcgcgcat tgagcagctg taagctttta tcgtcagaaa tcactggcac agttgcctgt
     4201 ttggcttgca tataaaggta ttttgctctc acaagatcta aatgtcctag tagccaagcg
     4261 ttattcctaa gagatcgact atgcggacgc agctgctctg acagctcatg caagattcgt
     4321 ccaatctcat ggcgttcatc tgtctgtagc tgagtcagct cctcattgag acttacaagc
     4381 gctctaggct caatgtagac cgtactgcca gaagctgaca tgtcatgcac aacgcctgcc
     4441 accttatgac gataggtgtt tttgacaggc aggacacttc ggccattacg actagcaatc
     4501 aggctctctg acaaataagc tgcctgtttt tttaggatat cctgcaggag ctgacgactg
     4561 gcatgctcct tgtttgatat ctgacgacga atgctctcca attcaggact agcaaagcct
     4621 tcaacaaagc ctgcgtcatt aatggcttgg agactcccct gtaagctagg aaagctctct
     4681 attttttcaa agagtgcttt tagagcgact aaatcaacat tttccaaatc agcgtaaaaa
     4741 cgacagacct ctgccgacac ctgcaggagc tttttaactg ctaaaagctc ttgaatgctc
     4801 agatctgcct ctaaatccaa acgctgcatg ctttctgaga catctgatag ccctcccaag
     4861 gcaaaatggt ggtgctctac aaaaatagcc gccatttcct caagctctgt aaagtaagcc
     4921 tgtattttgt ctttattcgc aataggctcc aacaagtcaa gctctagctg cccctgctct
     4981 gtctgtaaat aaggccaaaa ttgctcttta accttttcaa attctaactg ttctaaaatc
     5041 tttttttcca tagttcttat tatacctaaa aatcacttaa aatgtgggac actaaacaaa
     5101 aagagaccag agagactctg acctcaaaga atagctgtta cccataattg cctgagaatg
     5161 cttgagataa agggacaatg ctcaaccaag aggcgagaca aaagactgcc atgtaggcgc
     5221 ccttgaataa agggcatggg aatggtagca agaacggtca atgccatgct taaaaacaaa
     5281 accgaaacca tcaccgccag caagccactg gctagcttag cctcaaagcc atcaaaataa
     5341 tccaccggcg caaggtgcac caagacaccc gccaatcgaa ccacagcata gcctactgta
     5401 gacagtataa aaaatgctat ccctgcataa taaaccttat ccaattcaaa aatattaata
     5461 tccttaaaaa ataaggtagc tgctccctca gcaggattag aataaggcac ccatagagcc
     5521 agcttgcctg ccagagcctt atagccatga tgggcaaaca agagcgacac caaggcccca
     5581 aaacaataaa aggtctgaag gataagccct ctattgtagc caatgtaaaa gctccaagaa
     5641 agcagtaaca atataagcac tgagagcatc atgacacctc atctgtatct gcttgactag
     5701 ccttttcctg aatacctgcc agtgccttct cacgcagctc gacaatctca gcttcgattt
     5761 tttcaatctc aatctctcta ctcagttggg ctgacagggt attgatggtc atcaaaatag
     5821 caacggtttc gtcgtctgct tctggcagac gctccttgat ggcctgatat ttttcctttg
     5881 ccacacgatc aacctcttcc ataaagaggt tgtctttgtc cgttgtcaat gttaatgtct
     5941 tctcaccaaa tgttaatttg taacgattaa tattcttcat aggctcaccc ctttagcatt
     6001 ataccctaaa aatgactttt cgtaaaattg tgaaattaat ctgagattgc atggaatgat
     6061 ttcccataac aggacatttt atgttaaaat aatgttcatg gacaccttag ttttcaaaat
     6121 caattcccaa gtcagcagca gcctgatcaa gcagctagca ccataccgca taagcaatgc
     6181 caatccttac gttagactgg ctgccaaaaa agatggtgtc acactgatgc tgtatacctc
     6241 aggcaagctg gtgctgcaag gcagacaggc tgcaaagctg gctcaagagc ttgatctgca
     6301 agaaacgcct gctgatcaga gacccgcacc ctccagcgca caggatatcc ccttaattgg
     6361 tagtgatgag gtgggaaatg gctcttactt tggaggcatt gctgttgttg ctagctttgt
     6421 gcagccagag gagcacgcct tgctcagaca gctcggtgtc gatgattcta aaaacctcaa
     6481 tgataagagt atcgcccaga tcgctcctgt cctaaaaaag catattcaac acagggcgct
     6541 tttgctatcg cctaaaaaat acaatgaaat ggtaggtaag gggaagccct acaacgctgt
     6601 ttctgtcaag gttgctcttc ataatcaagc gatttttctg ctcttaaacg acggagcaag
     6661 accagaaaaa attgtcattg atgccttcac aagtcaggcc aattatgaca aatacctaca
     6721 gcaagaaaaa aatcactttc gtaatccctt gacctttgag gagaaggccg aaggcaaata
     6781 tctggcagtt gctgtcagct ctatcattgc tagacagcta tttttagaca atcttgacaa
     6841 gctcagtcaa gatctgggct accggttgcc tagtggtgct gggcgtccat ctgatcagat
     6901 tgccagtcaa atcttagccg cctatggtat ggcaggctta gagcattgcg ctaagctgca
     6961 ctttgcaaac accaaaaaag cccaagcgct actaaaaaaa caataatctt agaaaaataa
     7021 aggaaaagtc atgaaacaat ttattaaaga atggggagct tttacccttt ttatcctact
     7081 ttttggactc tcacgtttgt tcctatggca gcctgtcaag gttgatggcc actcaatgga
     7141 cccaacccta gcacatggcg agaggctcat tatcttcaac aaggctaaga ttgatcgctt
     7201 tgatattgtt gttgccagtg aggaggacga gaacggacag agaaaagaga ttgttaagcg
     7261 tgttgttggc atgccaggtg ataagctgtc ttatagaaat gacactcttt atatcaacaa
     7321 caagaaaaca aaagagcctt atcttgatac ctacctgacg agttttaaaa aggacaaatt
     7381 acaatcaacc tatgcttaca gtgatctctt ccaagagctg gctgaaaatg ctgctgcctt
     7441 taccgtcaac tccgaaggaa aaacagaatt tgacatcact gttccaaagg gcgaatattt
     7501 cctactgggt gatgaccgca ttgtatctcg tgacagccgc gaggtcggct cctttaaaaa
     7561 gcaggacatc gttggtgagg ttaagttccg cttttggcca ctcaataaaa tcaatctctt
     7621 ccctagatag caggcaagct aaagctattt tctagcaggg ctgatatagg ctctatgccc
     7681 acagcagtaa agactcaggg cagcaatagc ctctatctat atctgcttat ctatccatac
     7741 caagaggctt gatgtgctat ccaagcactc agctagcttt agagaagcag ctattgttga
     7801 cgttctaaaa cctgccgttg tgcaggtttt cgactatctt gcacagaaag gtaccgtcat
     7861 ggaacacttt tttacaggca ctgttgaccg aattatcttt gacaatgcgt caaatttttt
     7921 caaaattcta ttactggcta tagaggatac tgatagtgat tttgatgaag ctgacattgt
     7981 cattacaggc actatggctg agatcataga gggcgaagcc tatacctttt ggggtgagct
     8041 gacccagcac ccaaggtatg gtcagcagct gcgcctgagc cgctatcaaa aggctaagcc
     8101 cacctcagca ggtctcgtta gctatttttc cagtgagcat ttcaagggca ttgggcaaaa
     8161 aacagctgag aaaatcattg ccctttacgg taataatcct attgatgaga ttttaaaaaa
     8221 tcccagtcgg cttaatgaga tctctagcct ttctaaggct aatcgtgaag cctttgtggc
     8281 aaagcttaaa gccaattatg gcactgagca ggtgattgct gccttggctg atctaggact
     8341 ggccaatcgc tttgcctttc agctatttga caaatacaag gaagaggctg ttcatatcgt
     8401 caaggacaat ccttatcaac tcattgagga cattcaaggc tttggcttta agctggctga
     8461 tagcttagct gaacagctag gaattgagag tgcctctccc aagcgctttc gtgcggctct
     8521 gctgcattgc ctgttggagc aatccatcaa gcgaggcgac acctatatcc aggcacgtga
     8581 gcttttggcg ctgaccatta gcctattaga ggacacaagg ccagtcgaat gcgacccagc
     8641 tattgtcgct aatcagctaa cccagctcat cgacgagggc aaggttatga ctattggcac
     8701 gcgtgttttt gacagcagcc tttattatgc cgaagacggc attcaaaagc atctgacacg
     8761 cttactacag cagcctctga ctaaggagcc tagtcaagat accattgacc aagaaatcca
     8821 agccatacaa gaggagcttg ctataaccta tgacaagatc caaaagcagg ccatcagcca
     8881 ggcactgacc agcaaggttt tcattctaac aggaggccca ggcacaggaa agacaaccgt
     8941 tatcaggggc attttacagg cctatgccag cctgtaccag attgacctga aacaaaagga
     9001 tattcccatt atcctagcag ctccaactgg tcgagccgct cgtcgtatga acgaattaac
     9061 cggtctagca agcgcaacta ttcaccgcca tcttgggtta aacggagaca atgattacca
     9121 agcaatggag gattatttag actgtgattt gctgattgtt gatgaatttt ccatggttga
     9181 tacctggctg gccaatcagc tattaacagc catcaattct aatacccagc tgatcatcgt
     9241 aggagatagc gaccagctgc cttctgtcgg tcctggacag gtactagctg acttgctaaa
     9301 ggttgatcgg atccctcaca ttacccttga caagattttt cgccaatcag aggagtcaac
     9361 cattgttgat ttagccaacc acatacgcca aggcattctt gctcctgatt tttgtcagaa
     9421 aaaggctgat cgctcctact ttgaagcgca agcgccattc attcccggca tgatgacaaa
     9481 gatcgtacag gctgccctaa aaagtggcat cccagctgag gaaattcaaa tcctagcccc
     9541 tatgtacaaa ggactagcag gcatcaacag cctcaaccag ctcatgcaaa acctcctgaa
     9601 tcctctagct aatcagacag aatttctctt taacgagacg gcctttcgta agggagacaa
     9661 ggtacttcac cttgtcaatg acgctcagct taatgtcttc aatggtgata ttggctatat
     9721 cacagacctc attccagcca aatataccga atccaagcag gacgaaatca tcatggactt
     9781 tgatggcacc gagatcgtct acccaagaaa tgaatggtta aaaatcaccc ttgcctatgc
     9841 catgagcatt cacaaatctc aaggcagtga atttcaggtg gtaatcctgc ctgtcacccg
     9901 tcagagtggt cgacttctgc aaagaaacct catctacact gccatcacca gatcaaaaag
     9961 caagctcatc atgctcggag aaatagccgc ctttgaagag gcaatcaaaa aagaaggtga
    10021 caagcgacac acctatctcg tacaaaggct tcaagtggct gaagctgatg accatacagc
    10081 agctgcttca gtaaaggaat caaatcagtc tagcctatct gtaatgccag ctaccagccc
    10141 acaaaaggaa caagagcagc ctccttatct gctcacccct cataatttcc tagctataga
    10201 ccccatgatt ggtctaaccg aagatgatat gttaaccttt tttaagaaaa aatcataata
    10261 tattaaaaaa gtaaggcaca atccttattc ctatgctata atatccatgt atcatcttaa
    10321 aagtacaata acataacatt caaggagact tatatgattt catacgaaca agtacgacaa
    10381 gcactcagaa catcaactat tacgatcatt atcatcaatg ctatcagcat ggttatcacc
    10441 ttgtttggac ttgctggcat tttctttttg aagtctcaat tggataaacc tgaatttcgt
    10501 gcacaatttt cagctgagca gctaaggcta tttgaggttg gcatatcacc ctttactatt
    10561 tttatgtcag tgattagcct tggattggtt gttttgacca ctgtgctttg tggctttaac
    10621 ctctcaaaaa tcaaacaagg ttccactgtc agctatgttc cttacattat agggattgtg
    10681 ctctatctta ttagtatcgt aagccaacta tttagccaaa ttgagcctgt ctcaatgatc
    10741 attgtcctag ctgagcttgc gctttacggc tttgcctttt acaaggctaa aacccttaat
    10801 gaaaaagaca aggacaatcc ccaaagcatt gaagaataag caggccataa aggtatgata
    10861 acaagacttc ctgtctgcct tcaaatatgg ctctttgtca gcccactacg gttgacaaag
    10921 agcctttttt aaccactaaa aaagcaagag gaaaattgat aatgtcctct tgcttttttt
    10981 gttagttgaa tgacaggtcc aacaaaatat ctgtcacttt atcctttagt ccggtcattg
    11041 tgactcccaa taagcggatt cctgcctgat gctcctccag gctatcaaaa agctctctag
    11101 ccacctgatc aatgatccta gcatctcttg ttaactcagg taggctaacc cgcttggtca
    11161 aggtcgtaaa gtcagcatac cgaaccttca aaacaatgat ccttcctagt tttttattcg
    11221 cctcaagcaa atcagcgacc cgtcttgcat gtttagaaag ctctgcctta atatcagcct
    11281 cctggtagag gagcttagca taggtacgct cactgctgat ggatttgcgc atacgattag
    11341 gcttgactgg agaatgacta atgcctctgg cctttcgata aagctcatag ccaaagcgtc
    11401 caaactgatc aatcagggtc atctcaggaa cacgcaaaag atcctgccca gtgtaaatcc
    11461 ccatctcatg cagcctttca actgttcgct taccaacgcc atgaaacttt tcaatcggaa
    11521 gcttttctaa gaatggcaga gcatcatcag gaagtactag ggtcagacca tgtggctttt
    11581 caaaatcact agctagcttg gctaaaaatt tgttataaga aacaccagca gagcaggtca
    11641 actgcaggct attccaaata tcatgctgaa tcagtcttgc aatctttaag gcagacttga
    11701 tgcccagctt attggttgtc acatctaaat aagcctcatc aatagacaca ggctccacct
    11761 gatccgtata acgcttgaaa atctctctga tatcatagcc aatcctacgg tacttagcat
    11821 gatctccaga gataaaaata gcctgaggac aacgctcgta ggcctccttt gagctcattg
    11881 cagagtgaat gccaaacctt cttgcctcgt agttacaggt tgatacaacg ccccgtccac
    11941 cactttctct agggttcttg ccgatcacca ccggcttgcc ctttaattcg ggattatctc
    12001 tttcttccac cgcagcaaaa aaagcatcca tgtcaatgtg tataatcttg cgtgaggtgt
    12061 cattaatcag cggaaaaata agcataggtc cctccctcct acattatact cctttaggct
    12121 tttaaagcca aggcagagga ttgtatgaca gttttcaact gtttcagcaa actgtaatat
    12181 aaaagaatct tgtatttgtc aagatttttg cttgggaaat cgtttcccct atggtaaact
    12241 tagattgtaa atgtaacaga ttggacttgt tactagattt taaggagaaa cttatggcaa
    12301 ctgttaaaac taacgcagat gtttttgaaa aagcttggga aggctttaag ggaactgact
    12361 ggaaggaaaa agcgagtata tctcgttttg tacaggctaa ctatacacct tatgacggtg
    12421 atgaatcatt cctagcaggt gttactgagc gttcattgca catcaaaaag gtcattgagg
    12481 agactaaagc tcactacgaa gcaacacgct tcccatacga tactcgtcca acctcaattg
    12541 ctgacattcc tgccggattt attgacaagg ataaggaatt aatctttggt atccaaaacg
    12601 atgagctatt caaattgaac ttcatgccaa agggtggtat ccgtatggcg gaaacaactc
    12661 tgaaggaaaa cggctatgag ccagatcctg ctgtacatga gattttcact aagcatgtga
    12721 caacggttaa tgacggtatt ttccgcgctt acacgtcaaa cattcgtcgt gcgcgccatg
    12781 cccacactgt aactggtctg ccagatgctt actcacgtgg tcgtatcatc ggtgtttacg
    12841 cacgtcttgc cctctacgga gcagattact tgatgcaaga aaaggtcaac gactggaatg
    12901 ccatcactga gatcgacgaa gaatcaatcc gtcttcgcga agaaatcaac ctgcaatacc
    12961 aagcacttgg cgaagtggtt aagttaggtg atctttacgg tgttgacgtt cgtcgtcctg
    13021 ctgaaaacgt caaagaagct atccaatggg ttaacattgc ctttatggct gtttgccgcg
    13081 tgatcaatgg tgctgctact tctcttggac gtgtcccaat cgttcttgac atctttgctg
    13141 agcgtgacct tgcacgtgga accttcaccg aatcagaaat tcaagaattc gttgatgatt
    13201 ttgtcctcaa gcttcgtacc gttaagtttg ctcgtacaaa ggcttatgac gctctttatt
    13261 caggtgaccc aaccttcatc acaacctcta tggctggtat gggtaatgac ggtcgtcacc
    13321 gcgttacaaa gatggactac cgcttcttaa acacacttga caatattggt aactctccag
    13381 agccaaacct aaccgttctt tggactgata agttaccata tgctttccgt cgctactgta
    13441 tgcacatgag tcacaagcac tcttcaatcc aatatgaggg tgtgacaaca atggctaagg
    13501 acggctacgg tgaaatgtca tgtatctcat gctgtgtgtc accacttgac ccagaaaatg
    13561 aagagcaacg tcataacatt cagtacttcg gtgctcgtgt gaacgtgctt aaagcccttc
    13621 ttactggact taacggtggt tacgatgatg tgcacaagga ctacaaggta tttgacatcg
    13681 accctgttac tgatgatgtc cttgactttg atactgttaa ggctaacttt gaaaaatcac
    13741 ttgattggtt gactgatact tacgtagatg cgcttaatat cattcactac atgactgaca
    13801 agtacaacta cgaagctgtt caaatggcat tcttaccatc acatcaacgt gctaacatgg
    13861 gatttggtat ctgtggcttc gcaaatactg ttgacaccct atcagctatt aaatatgcga
    13921 ctgttaagcc aattcgtgac gaagatggtt acatctatga ctacgaaaca atcggcgact
    13981 acccacgctg gggtgaggac gatcctcgct caaacgaatt agctgagtgg ttgattgagg
    14041 cttacactac acgtctacgc agccacaagc tttataagaa cgctgaagca actgtgtcac
    14101 tgcttaccat cacttcaaac gttgcttact ctaagcaaac tggtaactct ccggttcacc
    14161 gcggtgttta cctcaacgaa gatggtacaa ctaacctatc acaacttgaa ttcttctcac
    14221 caggtgctaa cccatctaac aaggctaagg gtggctggct gcaaaacttg aactcacttg
    14281 caagccttga cttctcatat gccgcagatg gtatctcact aacaactcaa gtatcacctc
    14341 gcgcgcttgg taagacacat gacgaacagg ttgaaaacct tgttactatc cttgatggtt
    14401 actttgaaaa tggtggtcaa cacgttaacc taaacgttat ggacttaaat gacgtttacg
    14461 ataaaattat ggctggtgaa gacgttatcg tccgtatctc tggatactgt gtcaatacca
    14521 aataccttac accagaacaa aaaactgaat taactcaacg tgtcttccac gaagtgcttt
    14581 caatggacga tgccgctgaa gctatttcag gaaaataagc taatcttagc tagctaagag
    14641 cctgtctgtt gacaggttct ttttttatca cacatgcaat aggtacagct gtcctcagca
    14701 gctgaataac cagcagagct ggttgaaact actagcaagc ctatcattat cattgtgaaa
    14761 atcagacgat taaccttttc attaaaaaaa aaaaaacgaa actacggaga aaagctgatg
    14821 aggagctctt taaggctatc agtcaacatg ttaaactctt cttaggaagc gttaacaata
    14881 actaactgct aagctaagca attatctatt aaggagaata acaatgaaac gactaaaaac
    14941 actatgcttg ttagctactg ctataaccct aaccctagct cctatcagca caagccagac
    15001 aacaacacag accgtatatg ctagtgaaac tcatcaaaat ctttgtacga acactggtaa
    15061 cggatggttt aaatgtcccg atggacatgg agggtggact tggcattttg acgaaaatca
    15121 taagtcaaat cagcagtcct ttttgggagg attgttgggc tttgctttgt ctctatgggg
    15181 agctattatt agactctttt aagctctagc ttaactaatc ctcaaacaac aaaaataagc
    15241 tcttagagaa ctaagctcta agggcttttt gctgttctga taagtaaaaa ccaagagaca
    15301 aggacatcaa aaacaagcag gcctatcaga tataccacct gataggccca cttgtgctct
    15361 cattcttatc taggactatt tctgtcaaag gtcctatgaa tagcatcccg aagctgtcgt
    15421 ctctctttga tccacaaggc cctatcatcc ttgtcatagg ttctattggt gagaaaaatc
    15481 gctgcctgct gctccttttt attgagcatg ataaaaggcc ctgtatagcc tgtatgacta
    15541 atccaatcac cctctaggct ccaacccaaa gacctgggct tttcctgtct gctatagctt
    15601 tgaaaaagtc tatccgaaaa gctttccttc aggtaatgct caataaaccg ctctaaatcc
    15661 ctgatggttg aaaaaagccc tgctgagcct gcatggtttc ccaagacctt agccttggga
    15721 tcatgtacct ctccatcaag cacccctttg accgttggaa ctgcttctgg ccttgggcca
    15781 aaggaggtct cagtcattcc aaagggagta aaaaccatct cctgaaaaag ctcatcaaga
    15841 gactttccat gaaggtgctc tagcatgaag ccaagcaata aaaaattcac atctgtgtaa
    15901 tgaaaggtct tatcgtcctt gacctgaagc tggtgcatcg ctgctcttaa ttgctgggca
    15961 ttgagctgat ctcgattggg aatataaggg tcaagtccac tagtatgggt gagtagctgt
    16021 cgcagtgtaa cctccagctt ttgagcgtca ggataataat gccttaaagg agtatcaaga
    16081 gccaaggcac cactattgat catggctata cagacagtcg ctactccgac aaccttagag
    16141 acactggcta aatcataaac caagcctttg gtaacaggtc tttgaccatc aagggtaccg
    16201 atataatgct cctgccaacc gccacagcga aaaagggcta agctagcccc atgatataag
    16261 ccttcctgaa tctgctggct taccttttct atgacttcta atgtcatttg acaaaccaaa
    16321 tttcgatctg acttgggtct gaaagaacaa gcacccttgc ctttttatct aaataaacct
    16381 gacacccttt gtcctcaagg taggtcttta gagcaagcaa gtcatagcta tctgacacct
    16441 gaaattctaa aatctccaaa tcccatgtga catgcgggac aatcgtcaaa tcttgaccag
    16501 cctccctatt aaactcaagc gtgaccggca ggcaatcacc aaaaatagac tgataaaaag
    16561 ctctggattg ctcgtcatct aaaacattta agacaatcag atcaaagcta aactgactca
    16621 gccccctaaa gtcagcttcc ttgtcaattg caggaacatc atcgacaatg tcaagctcct
    16681 tgatatcgtc ctctgcatgg agtaagaagc gatctccctc tggtgaggtg acttcaaagg
    16741 catagccttt ttttcccttg aaaatcaaat catagtcaac gccatgagct aggagctgct
    16801 caatgtcctt aggagcagtt gttttgataa caattgtatt tactttctta gggccatcta
    16861 caacgcgtgt tcttgctgct ggagattctt caattacaaa gcgttcttgt ccttggcccc
    16921 aagatgaaaa aattgatatc gcgttttcct ctgacactag ccttaagcct agattttttt
    16981 ggtaaaaggc aatattaagg tcgcgattgt taacacgtaa tactggggtt ttaaagacaa
    17041 tattgtcaaa taaagtcata tattcctcct aatcctctgc tattatagac aaaattccaa
    17101 tttttgacaa gaaattatat gctttttaac cgcctgtcac gcgctaccaa ggcaatatag
    17161 cactcacagc catcaccaga cttactaggt ccaatcttcc ttcgtgcgct ctatcacaag
    17221 cagctttcct tagcgtaact catgcacata ttggtaaatg cgactttttc aaaatagcac
    17281 atgaagtacc cctttaattt gacttttcct taaccaaaag cgagaacctt ttttagttct
    17341 cacagtagca atcacactct tgaaatgtga tttcgctctc ctcaataaca gatgataact
    17401 gaaattgccc ggattttctt atccacgcgc aacttcaaaa gcaccttatc ttcagcatta
    17461 gtaaggatac taccagctta gctcagacca gattcagctg gctcttgctg gcaagctttt
    17521 atcacaaaaa agaaggccta agccttcttt tttacttgat ataaaggaat ttgaatgctg
    17581 ctactgctgc tactgctgct agcactgggg cagcaaccgg tacccatgag taccaccatt
    17641 ttgaatcccc cttggcttgt ccaaggactg attttggtaa gaaatggtga accaaacgag
    17701 ggcctaagtc acgcgctggg ttgagcgctg gaccagtagg accaccaaga gaggtcacaa
    17761 gagtcatcac caagaaacca atccccaagt gagctactgc aagtgagcct gtcacgtaag
    17821 gagagatttg cgttgcagct gttgtttggt catagccagc ctctaccagc ttaccaacaa
    17881 gctccacacc aaagtaattc ttggttaagg ccattgcgcc aaaaaagagg acaaaggaac
    17941 caacaaactc gttcaaaaag ccattaatgt aggctgcctt acggctgctc ttgtcaccat
    18001 catcaactgc tgaaatcgtt gagaaggatc ccaaaatatt gttagggttg tctgtctgca
    18061 caaaataagg cttgtacacc gcaacaacca ctaattggcc aaacatagcc cctagcaatt
    18121 gagcaagaac atattgtaaa acgtgtgccc aagggaacaa gcctgaaact gccaagccaa
    18181 aggtaaaagc tgggttaatg tgatttccag aaacgttacc aaacataagt gccggcatca
    18241 tcacaccgag gccatagcca aaggcaatca caagccagcc tgagcggtta ccctttgttc
    18301 cctttaagtc aacattggca actgctccat ttcccaaaat aatcaaaaat gcagtggcaa
    18361 taaactctgt gatgtatttc acagtccatg ttatttccat attctctagt ttcctccaaa
    18421 tgataagtat aacagatacc attttatcag ggatactagt tcttgtaaag cctattgtaa
    18481 gatattgcct gcttaatatg tttacagtgt tttttcacaa ttacggacaa ctaataagtc
    18541 ttttttagca tgtcgcagga tatactctga ggtcgatcca atcagcagac gctcaaaggt
    18601 atttaagcca gttgctccta ccatgatcaa atcagcctgc tccttttcag gtatgtcact
    18661 agctaagagc tttttagggt tgcctctttc gatgattttt ttaatgctgc taacgcctct
    18721 gcctctagcc attttctcgt aatagcgcaa cacctccttg gcatgctcct cttgtgtgtc
    18781 aaagacataa tcactaacca ttgcatcacc ctgataggcc ttaacatcaa taacatgagc
    18841 cagcagtaag accgcatcat tgcgaagggc aacattaatg gccttctcaa cagctaattc
    18901 tgattcgtaa gagccgtcca ccgcagccag aatccgttta tatttgctta tcatctttgt
    18961 ctcctttcgt tgattagcct ttatcaatag cctttgcttg tgtctttagg aaatacatga
    19021 ctgcgcaggc agctggaatg agccctgcca gccagaacaa ttgatgaaag gactgcacac
    19081 cagacccaag aagcatatcc ttgatgagtc ccaacagata aggtcccgca cccaagccca
    19141 aatctagccc aatcatataa gtagacatag cggtattaaa gcgatgctcc tcaaccccct
    19201 tgatggaggc tgcctgtccg caggacataa aggttccata gccaaagcct atcaaagcac
    19261 ccgaaagcag atagggaagg ctgcttgtca cactaccaag caggaaaagc cctagcgcca
    19321 aaaagagata gctgggataa agaacccact gctccccctt aacgtccatc aagcgtccca
    19381 tagcaggtcg tgtgatcgta atgatcaagg catataccac aaagaaatag gctcccaccg
    19441 tcgtcaaatg aatgtctgtt gtgtataatt tttgaaagcc tagcacagaa gcataggcaa
    19501 tccccatcaa aaaggcaatc aaggtgataa ataaggcctt tcgctcaata aagctatcaa
    19561 ctgtccagga ttttgttttt gccagctgct ctgagttgag ggcaatatct gtcacaggaa
    19621 aggcaaaggc ccctagcaca actactgcga tcaacacact gcacaaaata ataatcatcc
    19681 gaaaatcaat gtgcaaatta tccagcataa aggtcccaac aaaaggacca atcgccgccg
    19741 ctaggcttgt tgatagacca taaaaattaa tcccctctcc gcgcttgcta gctggaatat
    19801 aggcagtcac aatggtattg gttgctgttg agacaacacc atagccaaag ccattaaaca
    19861 agcgcacaaa atacatcatg ccaatcgttg gcatgaaaaa gtaggctagc gttgttagga
    19921 gataaaaaat ggcgcctcct cttagcacta agcgtcggcc aaaaacctcc aattgcttgc
    19981 caaaaatcag tcgagccagc agggttccta ggatataaat ccccgtcgcc agacctgcct
    20041 cactggtctt agctcctaat tccttagtcg caacaaaggc aatgatcacc gtaaacaagt
    20101 aatagaccat atacacaata aaatttaata ctgtgatccc tataaaatgc ttgttaaata
    20161 atttgtcttc cactgaaaat gagctcctcc ctatttcatt aacattttac aaaaaaatca
    20221 gataatgccc catttcaatg gtataatata ggtgatacta ttaaacgaca ttagcaaatg
    20281 ctaagcattg ctgcagcaac aaattatata atgataccag aaacacctct aggagaaaag
    20341 cgtgaaccat caaatcttac agcgttatat tgacagtcat aactttccta ttatcgaaaa
    20401 gggctaccac aaatacctga cctttgaaag cttagaggag gattttacgt atatcctaaa
    20461 ggagggcatt gtcaagcaaa gcgttctgtc aaaatatggc atggaattta acctcaggta
    20521 cgtcacaggc cttgagatca cctctgtgct taatactggc tattccaagg acatgagaga
    20581 gccctacaat gttcgcatcg aatctgagac tgccagcttt tataaggttc gtcattccac
    20641 ctttttaagg gatattagcg aggatatcga gctgcagggc tatgtcaagg acttttatca
    20701 ctaccgcctc caaaaatcaa tgaaaaaaat gcagtgtatg ctgacaaatg gccgtatcgg
    20761 cgctatctct actcagattt acgatttaat gacccttttt ggacgcccct tggctaatgg
    20821 ccatatcctt attgatttta tcatcacaaa tgaggagctg ggcaaattct gtggcatttc
    20881 gactgccagc agtgtcagtc gtctcctaaa gcagctcaaa aaagagggca ttattcaaat
    20941 caatgaccag catatcatca ttaccaattt agagaagcta aaggataata ttgtttttta
    21001 acgatttaga aaggacgtcc catgcgctat aatcaattgt cttacattcc caccagtcta
    21061 gaaacagctg tagctgagct tcaggccctg ggctttgctg tccagcaaga gcaagcaccc
    21121 aaggagaact tcgctatttt ccttagaaag ctattttttc attttcagga taccgattat
    21181 cccttgagcc atatgattgc aagcaaggat ctcgacctat tgaccttttt aacatctgat
    21241 gcaacactga caaaagaggt ttttgattta gtggccttac aggtccttgg ctttattcct
    21301 gctgttgact ttaccgatgc acaggacttt atacaaaaga ttggctttcc gattgttttt
    21361 gacagccagc aattactact caatttacat cagctgcttg caacccggca gaagtccggt
    21421 gtgaccttga ttgatagcct tgttagtcag ggcttgcttc ctatggataa ttgctaccac
    21481 tacttcaacg gaaaagccct agcaaccttt gataccacca gcctcattcg cgaggtggtc
    21541 tatgtcgaag cgccacttga taccgatcaa gacggacagc ttgacctcat caaggtcaac
    21601 attatccgcc ccaaggccag cactgctatc ccaagcatga tgacagccag cccttatcac
    21661 caagggatta acgagaccgc caacgataaa aagctccatc gcatggaagg tgagcttagc
    21721 cctaaggctc ctcgtaggat taccgttgag ccaactgatt ttcagccgct tgccaccaag
    21781 ccctcaaggc ttcctgtcaa tgagtgccaa gagaccttca gccatatcag ctcctacaca
    21841 ctaaatgatt attttctagc gcgtggcttt gccaatctct atgtctcagg agtgggaaca
    21901 gcaggctcaa ctggctttat gacaagtggt gactacgccc agatcgaaag ctttaaggct
    21961 gttatcgatt ggctaaatgg cagagctact gcttacacga gccacaagcg tgactatcaa
    22021 atcaaggctg attggtcaaa tggcttagtc gcaacaactg gaaaatccta tcttggtacc
    22081 atgtcaacag gactggctac aacaggtgtt gatggcttag cagtcatcat tgctgaagct
    22141 gccatttctt cttggtacga ttattatcgt gaaaatgggc tggtatgcag tcctggtggc
    22201 tacccaggag aggatctcga tgtgctgaca gagctcacct actcgcgtaa cctgctgcca
    22261 ggtgattact tacgtcacaa cgaccattat caacagctgc tgagccaaca atctcaagct
    22321 ctcgagcgcc aatcaggcaa ctacaatcaa ttttggcatg accgcaacta cctgccacag
    22381 gctgatcgca tcaagtgtga ggtcgtctac acgcatggcc tacaggactg gaatgtgaag
    22441 cctagacagg tctacaatat cttcaatgcc ctgcctgata gccttggaaa gcaccttttc
    22501 ctacatcatg gtgagcatgt ctacatgcac aactggcagt caattgattt tcgtgaggcc
    22561 atgaatgccc tgctctgtca aaaaatgcta ggacaaaata atggctttac cctaccaaca
    22621 atcatctggc aggataacca aaaagaacaa acctggaaag agctaacagc ctttggcggt
    22681 cacagcaagc gtcagattgc cctaggcgat gatcatgtct taattgacaa tcactatggc
    22741 gaagaggact ttaagcgcta tagcaaggat tttcgtgcct ttaaagctga gctttttgaa
    22801 ggcaaggcaa atcaagcagt cattgatatt ctgttagaag aggatctacc aatcaacggg
    22861 caagcctgcc ttaagcttaa gctaaaatca agtgaaaaca aggggatttt ggctgcacag
    22921 ctcctagatt atggcaagaa aaaacgcttt gctgatatac ctgctattct tgagctagac
    22981 agcattgaca acgggcagca gtttgcacgt gaagcgctca aggagcttcc cttcaaggac
    23041 agcccatacc gcgttgtcac caagggtgtc ctaaacctac agcaccgcag cgacctattg
    23101 accattgagg atattccaaa tgaccaatgg atgaccatca ccttccactt gcagccaacc
    23161 atctatcata tggccaaggg agacacccta agagtcgttc tttacacgac tgattttgag
    23221 catacaatcc gcgacaatag caactatgcc ctaaccctag atttggagca atcctatctc
    23281 ctaatcccta ctgatgagga ggaataaatc aaagcgcatc aaaaaagcct gagatcacaa
    23341 tgagctgcac cccaatcgtt agatcctttg tctaactgtt ggagtacagc tcaaagctct
    23401 aggctttttt aactattttg aaaccttttt accagcctca gcaccagaat gcaggctgta
    23461 gacggactcg atatgaatca agcctgctgc ctttggtgcg cccatcttgc cttctgccca
    23521 ttccttggca gcctcaaaga caggaccctc tgtaatgatt tccgcacgcc ctacaaagcg
    23581 ataaccacgc aattgctcgc gattgacata agcgacctca attttaccat tagcctgaat
    23641 attagagcag gtttggccgc cagtattttc attataaacc aaggtttcat cgtctaacag
    23701 tctcatcgaa cgcttagggc caatattagg attaccctca ttatctacag ttactaccat
    23761 tgctaattgc tcagcaatca tttctttcat ttcttctgtt aacatataat ctcctcttaa
    23821 tcgtttctat agtcagctga ctacgctttg attatagcac agttaagcag aaaagccgac
    23881 aaaaataggt tagcttaaaa aagttttaca gtttacttaa gattagaatg attctcgcta
    23941 tctagccatc acccttgatc acagtaaaaa ggcgattagc aagcaagcac tctttatttc
    24001 ataaaatccg aatcgtcgcc caaaaaaaat atcatcaact gatatggtca atgcctctgc
    24061 aatacctctt aatttttcat acttagctcg cctaagcttt tgcacatcct tttcatatct
    24121 ggctagtgtc ctaacagaaa tcccagttaa cgctgacagt tccttttggg tctttttttg
    24181 agcaatcctc aattccttta acgttgcttt tgacaatatt ttccctccgc ctctcatctc
    24241 aggtaatatt aatgacagat gacaagttta ttatagactt cggtttttat gaagtcaagt
    24301 cttttatcgc actttcccca cttctttttc taaatctttt gatttagctt gatttgtggt
    24361 atcatatcct atatagaaat aaaggagaat ggaaatgtcc gaaaagaaaa cattttttgc
    24421 aactaattta aaatatcttc ggctaaaaaa gaatatggaa caattagaac ttgctaacct
    24481 tttaggacga aaaagctctt cctcaatcag cgaatgagaa agaggaaagt acactccaaa
    24541 atctggtctc ctgagtgaca ttgctgccat ctttgatgtc agcctgacag acctcatgga
    24601 aaaggattta acactggaaa ataagggagt gacttatcag cttccccaaa gagatttagt
    24661 aatgatttca gagcagctat ctgaaaacaa ttataacaaa tggctggatt ttggtcagga
    24721 tctcttatct catcaggata aagaagaaaa tcacaagcca agcaaataaa gagcctcaca
    24781 cgtcttattc tcatcaagtt tcgaaaaatc acctaccact caagcacaca aaaagccttg
    24841 gcagggcttc taagcataag aaagctgtat catatcaata cctcagggac catgatatga
    24901 tacagctttt tgtatctcac ttttagacaa ggtagccaca taaagcttgc agatgaccta
    24961 cctctgtatt agctaccaca accaacagct agctagactg gcaggccctc tataagcctc
    25021 agcggattat ctaagcactc ccaacagctc caacaaaata aagacataac caataccatt
    25081 atttaagata tgggctactg ttgaaaaata gatattcttc ttccaaacat aaactaagcc
    25141 gagcaaaagt cccagtccac catacacaac gatggaagat agctcgctga aggaatagat
    25201 atgaaccaag ccaaatagca atgatgatcc caacaatcga gccagcagca tacctgtgcc
    25261 tgattggccc tcaccgatta aaatcttgcg gaaaataagc tcctcattga agggaccaat
    25321 aatactcacc accagaataa agatcactgt ctcgaagccc tcactagcat tatagcgatt
    25381 agctaaaaca gctgcattgc tgctctcttc taaaggaagg ctactgagca aaatatttgc
    25441 aacataaagc actgcaaaaa tgaccaagac ccacaaggta tttttgaccc attttgttga
    25501 aaactgccgc cagtccctct gataatctgc tcgataaagc caacagatcc caagtgcaaa
    25561 aatcagcaga tgtctcccgt aaaataaaaa ggtattcaat aaaggcggaa gctcaatcac
    25621 attgctaact tgtctataaa gatacacagc aatgatatat agcatgacca gtacagctgc
    25681 acgatgacgt ttgatggtat ccaattactc ttcctcaatt ctaataattg tcagattagc
    25741 taggctatat tgccatcagc taatcttgat cttaaatgtg actaatttac aagcactcaa
    25801 cttttgaatc ggtaaagctg acagacagcc ctaccctagc ttcaataaag ctatcttcca
    25861 atagtccttg cgctcatcag aactgtcaaa ggcctgaccc agctgagtca acagacttat
    25921 ccagtcaaca tcacacagaa caagaccatc ttaccatatc cctgccaact ataaaagccc
    25981 ctaacctgac ctatttgact actaacagca aaaaagcagc ttaaaaacac caatcagacg
    26041 ccaccaagga ctcttgatca gcgcagctcg cacagacacc tgaaaaatga cagacaagcc
    26101 tcttaaaagc acctcagcaa gctgagccaa cccttcacag aatagacaaa caacaagagc
    26161 taagtcaaga cctcaagcta gcagattaca ggcagagacg cttgcaaggc ttacccagca
    26221 aaaagcaaca gactgataaa ggattcacac cacacagcca caagtcaagc agctagccca
    26281 aacaaagcac tgctcaccaa atcctactat gctttctggt agcccttatc cattcaaaat
    26341 cgtatccaag gcttcttgat attgcttgtc tcgcaattct ctgatcacct gtgataaata
    26401 ctctgcctga tacatcacaa agtcaaaatt gaaatccaga attttggtgt tctcattcaa
    26461 tgacagcctc tcctcgataa aagcagtcat ctcagctgtt gtcacaatca agtcaaaatc
    26521 agttctccaa ggcaattcag cctctgacaa aatattaaaa cgatagacct ttgcaacaca
    26581 aggactcacc tgttgcatga ccaagctata taaaatatca atgtttttct tgttgatttc
    26641 gatcactgct atggctaaag gtggcagacc ttctctaaca agctgttcca gtcgcgtgca
    26701 aagcaaatgc aaattagagc ctgtcagccg accaacacca gaaacccgct ctgcccagct
    26761 attaatcatc agctcgatac gattggccaa gagcttactg ccttgatatt cctccgcata
    26821 ataatatttt tgcgggataa agagcgacaa atcaaacaag gtcttacgaa aataaggaat
    26881 caaggtctga atacaagcct tgtcaaaggc gatatagtgg ccaaacaatt gacgcagctc
    26941 acccagcagc tcttggtaag caggatcctc ctgaatgatc gtcaataagg ccgaagaatc
    27001 ctcctcagac cattgtgtga tcgaaaaaga gttgttaacc gtcaaataaa cgagaaaaat
    27061 ataatcaatc tcgctactgg gaaagtccat atcaagcaac aatttcccct cacgcttgaa
    27121 aaagtcctcc aaatacccat aaagcgccaa agactttaag cgtttaaaaa tcccctcctg
    27181 aggaatcgca acgtcaaact ctccacgctt ccaagatagc gacaagagca catcaaaaaa
    27241 gcgaaacttc ttatccagta acgggtgagg cgtttgttgc tttttgatcg aaaagataaa
    27301 gtcatgcaca atatccagat catggtcagt cagctcatag atgacaatcc cgtacttatc
    27361 atgcaataaa gcaatcaaat agcggatacg ccactcctca ccaacaacac tattatcctc
    27421 taaggccaag ccgcactcct caacaaaggg cttcatgtgc tgaatcagcc gataagctga
    27481 cggtgtggaa ataaaatgct ccctagcaaa gcctgagaca gatttgacct tatagcaagg
    27541 tgccttgatc aagagaaatt taagaatgtg cagccgtacc gattggcggt aaatcgtctt
    27601 caaaaacggt ttgccccttt tcaaaacggt gcagcggaca atggtgctat cccactcaaa
    27661 ggcgatatct ccttggaaaa gctcctctaa ttggtggata tagcgcttta tgttagctag
    27721 gctaaagccc gtcttttgct gaatggcgtg gaaactgatc ctttttttac caagtagtat
    27781 ggtcagcagc aaagcctgat gattaatcac tggttccaaa tactcttcaa gcaaaacact
    27841 ttctcctcct taaaccattt cgttagcgtc attatcataa caatttttac caaaaaagtg
    27901 atgaaaaata tttaatatca ggacgatttt tctgatagcc tttattataa cacaaaagct
    27961 caaggcaggt aaaacgataa agaaatcaac ttaaaactat gacacagtct catctcatat
    28021 gatatagtta ttcaggtttc ctaatggaaa acatattaac aacttaataa tggagagaag
    28081 aaagttgaaa acaaaatcat ttagaaaggt actgacaacg tcagctacct gtattgtgct
    28141 ggcaacaagc tttgccggag gaaccctaag agtctgggca gagcagcttt attatgggtg
    28201 gaatgatgga acgagacaaa gttcgccata ttttttgtac gtatcgccta aaaatgctcc
    28261 aaagcgtgaa ttaaaagacg agtatgttgt ttattgcttt aacaaaaaat tgtattggcc
    28321 agatcaatgg gaatctatat acagcaattt taatgacatc agatctccat ataacgattt
    28381 acctgtatat gagaaaaaac taggatatga tggtatattt aaacaatatg ctccagatta
    28441 caaaaaagat attagtgata tcgcaagtgc tttggtggca gttttaagta atggataccc
    28501 cactaacaag tcacaactat caactagcta ccatttaaat aatgattctt ctagaaaagt
    28561 tactcaatta gccatttggt attttagtga tagtttaaca aaagaatacc ttaaagatac
    28621 gggtggttat aacttaaacg atatggaaaa aaaagcttta gattttttaa tcagtaaagg
    28681 agaggattct aagcttaaat cagagcagag taattactca ttggatattt atgtttatca
    28741 aagtggcggg catgaccata tgaaagatta ccaaaatctt ctcggctcta ccttaattcc
    28801 taaagaaccg ctaaagcctc agctaggtgg ttttagtgga cataatggaa atggattaag
    28861 cggccttgaa ggaggatcat caggttcaca agaaactaat gaagatggta agaaaggact
    28921 tataggtttc catggaggac tctcaggaag cgagggcaaa cgagatcctt tccaggattg
    28981 aagggtgagg ctggtgcacc tgatacacct caaaagccta atgacccatt gcaaagtctt
    29041 gaaggtggta actctcctat cgtagaacaa aactatggta gtactgaggg atatcatggt
    29101 caatctggca ttcttgagga aaccgaagac actaacccac ctggtatcat tttaggtggc
    29161 tcaggaaatg tcgaaacgag atcctcatct gatggggctt ggcggtggtc tagctggcga
    29221 atcaggagaa acgacaccta aaccaggaca gactggtggt catggaccaa tcatcgagac
    29281 aacagaggac acacaaaaag gcatgtctgg gcaatctggc ggcactatcg agtcagaaaa
    29341 caccaaaaag cctgaggtca tgattggtgg gcagggacaa accatcgaaa caacagagga
    29401 cacacaaaaa ggcatgtctg ggcaatctgg cggtactatc gagtcagaag acactaaaaa
    29461 acctgaggtc atgattggtg ggcagggaca aaccatcgaa acaacagagg acacacaaaa
    29521 aggcatgtct gggcaatctg gcggtactat cgagtcagaa gacactaaaa aacctgaggt
    29581 catgattggc ggtcagggac aaatcatcga cttctctgaa aacacgcaat caggtatgtc
    29641 tggacagtct ggagacacta cggtcattga ggataccaag aagtctgaga taatcattgg
    29701 tgggcaagga caaatcatcg acttctctga ggatactcag ccgggtatgt ctgggcaatc
    29761 tggaggcacc acaattgtcg aagacaccaa gaagccgaca cctaagccta aacctgcacc
    29821 tgcgccaatt gttaatgacg aaaaacctaa caaaggcact cagctcccac agacaaatga
    29881 tatgaagcaa ctcaccctaa gcatcatcgg tgcaatgtca atgctgcttg tcctatgtct
    29941 gtctctattc aagcgaccat ctaaaaaaga ctaagcaaca ctgacaagtg atcattattg
    30001 tacggacgtt tacaggcggg ctttctgccc tcttaaaaca ccgtacaaca acaaaacggt
    30061 ctaaatagaa atatccctca agggttagac aatcgctcta gcccttgggg ctttttttga
    30121 tacttataat agaagagagc aagcagtgac actttctttt tgccctatat ctgctaacac
    30181 tagcggtatg tgcagttacc ataggctatc aactcgtcgt gcaactctag agaaaagctg
    30241 atacaaaaaa caagcaccag ccttgctgct gatgcttgct ccggacttac tgataagcct
    30301 ttgtgatgtc ctagctttat aaccatatgc ctattaccta aaggtctagt ctcctaatgg
    30361 tgggctggct ggtaaaagca aggagaaaca gctccccttt ccaagctggc tctcaacagc
    30421 aatatcccca cctagttggc gagctaactg cctagcaata gagagcccca gcccatgacc
    30481 accagtcttc atattgcgag aggcctcaac acgatacagg cgcttgaaaa tcaaaggcag
    30541 gtcctctttt ttgatccctt gcccctgatc aataacatca atgcgaatgg actgctcctg
    30601 ttgataagca tgaatcgtca aagccgtatt agcctttgaa tatttaagcg cattgctgac
    30661 taaattcagc ataatccgag acaaagcatc atatcggctg ctgatcttaa ccacctcttt
    30721 tgccacctca atatgaacgg agcgtttttc ctgctctaag gtcaattgaa attcggatag
    30781 catgtcaatc aatagctttt caagatagat gatttgaagc tgctgcttgt cgtcttgctt
    30841 ttgatcattt aagctgacca tatgcaattc ttcaactaat tgattcaaac ggttggtctg
    30901 tcgtgagatg gtgtttagat agtgcctttc ctcttccctt ggaataacgc catctaaaat
    30961 cccctctaca gttgcttgaa tagaggtcaa gggtgtctta atatcgtgcg acagctgagc
    31021 aatcatcatg gatttctcat gctcactctc actcaatgac tcaaagctga cctttagctc
    31081 tgaggacatc tgattaaagg cttcctctag atctttaaac tccaaaggac acttgatgag
    31141 ctgaccacta tcaaagtttc tttcagaaat agcctgtatc tttttcttta gccttttaag
    31201 cgatgaaaaa acattactca aaaggatcat attcacaatt cctccggcta ctgaagcaat
    31261 tagagctatt actaaaatat atgaaatatc ctcaatggta atgagcattt ggtttaaccc
    31321 aacaatcagg cctgcaatag taatcagcat agacattaaa tagccaatga caatgtacgt
    31381 tcttaatcgc atgctacccc tctaatttat aacctagtcc ccaaaccgtt ttaatggttg
    31441 gtgtttgctc ggtactgtat tttgccaagt cattgcgtag ggaatgaatg tgaacattta
    31501 aggtattggt atcatctaaa tactcctcct ccca
//
LOCUS       DARYLD010000019        31371 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYLD010000019 DARYLD010000000
VERSION     DARYLD010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31371
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..165
                     /locus_tag="TU651_000762"
     CDS             <1..165
                     /locus_tag="TU651_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896777.1"
                     /translation="VTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAA
                     IDQKLGCDFS"
     gene            162..554
                     /locus_tag="TU651_000763"
     CDS             162..554
                     /locus_tag="TU651_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896778.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            574..858
                     /locus_tag="TU651_000764"
     CDS             574..858
                     /locus_tag="TU651_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896779.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     regulatory      1512..1637
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            1710..2288
                     /locus_tag="TU651_000765"
     CDS             1710..2288
                     /locus_tag="TU651_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0896780.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     gene            2278..2928
                     /locus_tag="TU651_000766"
     CDS             2278..2928
                     /locus_tag="TU651_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL0896781.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            3119..4042
                     /locus_tag="TU651_000767"
     CDS             3119..4042
                     /locus_tag="TU651_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL0896782.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            4055..4840
                     /locus_tag="TU651_000768"
     CDS             4055..4840
                     /locus_tag="TU651_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL0896783.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            4850..5407
                     /locus_tag="TU651_000769"
     CDS             4850..5407
                     /locus_tag="TU651_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0896784.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            5535..6869
                     /locus_tag="TU651_000770"
     CDS             5535..6869
                     /locus_tag="TU651_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL0896785.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            6946..7737
                     /gene="pflA"
                     /locus_tag="TU651_000771"
     CDS             6946..7737
                     /gene="pflA"
                     /locus_tag="TU651_000771"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL0896786.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            8237..9172
                     /locus_tag="TU651_000772"
     CDS             8237..9172
                     /locus_tag="TU651_000772"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL0896787.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            9239..9892
                     /locus_tag="TU651_000773"
     CDS             9239..9892
                     /locus_tag="TU651_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL0896788.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(9997..10995)
                     /locus_tag="TU651_000774"
     CDS             complement(9997..10995)
                     /locus_tag="TU651_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0896789.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(10992..12017)
                     /locus_tag="TU651_000775"
     CDS             complement(10992..12017)
                     /locus_tag="TU651_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL0896790.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            complement(12027..12965)
                     /locus_tag="TU651_000776"
     CDS             complement(12027..12965)
                     /locus_tag="TU651_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL0896791.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            complement(12990..13769)
                     /locus_tag="TU651_000777"
     CDS             complement(12990..13769)
                     /locus_tag="TU651_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896792.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            complement(14029..15474)
                     /locus_tag="TU651_000778"
     CDS             complement(14029..15474)
                     /locus_tag="TU651_000778"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL0896793.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            15560..17191
                     /locus_tag="TU651_000779"
     CDS             15560..17191
                     /locus_tag="TU651_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL0896794.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAA
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            17341..17970
                     /gene="upp"
                     /locus_tag="TU651_000780"
     CDS             17341..17970
                     /gene="upp"
                     /locus_tag="TU651_000780"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL0896795.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            18201..18791
                     /locus_tag="TU651_000781"
     CDS             18201..18791
                     /locus_tag="TU651_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL0896796.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            18896..19342
                     /locus_tag="TU651_000782"
     CDS             18896..19342
                     /locus_tag="TU651_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0896797.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            19343..19627
                     /locus_tag="TU651_000783"
     CDS             19343..19627
                     /locus_tag="TU651_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL0896798.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            19943..20578
                     /locus_tag="TU651_000784"
     CDS             19943..20578
                     /locus_tag="TU651_000784"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL0896799.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            20592..21467
                     /locus_tag="TU651_000785"
     CDS             20592..21467
                     /locus_tag="TU651_000785"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL0896800.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            21464..22264
                     /locus_tag="TU651_000786"
     CDS             21464..22264
                     /locus_tag="TU651_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0896801.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            22257..22580
                     /gene="yabA"
                     /locus_tag="TU651_000787"
     CDS             22257..22580
                     /gene="yabA"
                     /locus_tag="TU651_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL0896802.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            22585..23451
                     /gene="rsmI"
                     /locus_tag="TU651_000788"
     CDS             22585..23451
                     /gene="rsmI"
                     /locus_tag="TU651_000788"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL0896803.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            23957..24112
                     /locus_tag="TU651_000789"
     CDS             23957..24112
                     /locus_tag="TU651_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0896804.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            24171..24371
                     /locus_tag="TU651_000790"
     CDS             24171..24371
                     /locus_tag="TU651_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0896805.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            25039..25632
                     /locus_tag="TU651_000791"
     CDS             25039..25632
                     /locus_tag="TU651_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL0896806.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            25972..27477
                     /gene="glpK"
                     /locus_tag="TU651_000792"
     CDS             25972..27477
                     /gene="glpK"
                     /locus_tag="TU651_000792"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL0896807.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            27651..28295
                     /gene="fsa"
                     /locus_tag="TU651_000793"
     CDS             27651..28295
                     /gene="fsa"
                     /locus_tag="TU651_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0896808.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGGHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            28679..30667
                     /gene="tkt"
                     /locus_tag="TU651_000794"
     CDS             28679..30667
                     /gene="tkt"
                     /locus_tag="TU651_000794"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0896809.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(30849..>31371)
                     /locus_tag="TU651_000795"
     CDS             complement(30849..>31371)
                     /locus_tag="TU651_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0896810.1"
                     /translation="GEKGEQGPRGEKGEQGPRGEKGEQGQRGEKGDQGQRGEKGDQGQ
                     RGEKGDQGQRGEKGDQGQRGEKGEQGQRGENGEQQPKGDQGKDTKPSVPKAPESPKMP
                     EKPQAPEKAPAPKAPKASEQSASPKAPAPQSTPSKKAVLPATGEASHPFFSLAALSVI
                     ASAGLLTLKRKKS"
BASE COUNT         8630 a         6179 c         7581 g         8981 t
ORIGIN      
        1 gtgacctatg acagccttgt gggtcagacc aagaggcatt ttgatgacaa ggttactcaa
       61 gctagaggac tggccacaaa gttcaagacc gtaaaggagc agctagagga gggggttgag
      121 agaacagctg ctattgatca aaagctagga tgcgactttt catgacagca ttagaaaaga
      181 tcagaactgc tatccgtcaa aaggaagagg agctagagga gcagcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctac
      301 agcagctcta tgcctctagc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gtctgataac agaccaatat accgttctaa cgaggctgat tgatgactac cagcaccgaa
      421 cagagcagtg ctatcatgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggcgatag aaaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga aagatgattg ctatagagat gatcttaacc
      601 ggacaagagc cgatcaggac tttaaagaaa gagctggata ggagattagt tcagtccata
      661 tgtgctccct tgaccttagg tcgccttcat gcccttcaaa ggcgctatga cagtgaggta
      721 tctcggattg ccacagacac cgcagatcat attcagacca ttgtcaatca gctagatagc
      781 agcattagag ggcaaggcag gacagcacta gagcaggcga tcaagacaca gaacaggggc
      841 tatagcagcc tgatgtgaga caagaaggac ttactgtcct accagctaca gtcactacac
      901 tgctagagct tgcggtgtga gcagcagtaa gaagcaaagg cgctgcccta gagggctgat
      961 gaatcaccat caccagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt cagaatgtag gcaaacccta tcagcgatag aaaaattgaa
     1081 catttagaaa ttgactatca tatcatgaaa actctgggaa atgctgatat tacagtattt
     1141 ttcagacttc ttttgttttt ttgattaaaa gaaaaagatt gaagaaaacc gtctaaaatg
     1201 gactttttct tcaatctgaa aactctgatt ggagttttca ttggttaggt gtgtctatga
     1261 ccgtaaaggg gacaacggta gtaataccag agcaggttat tggaggtttc ttctagtctg
     1321 ctcttttttg ccttgagcta ggctagtgcc atgtcacagg gtggcctacc tcgtagagag
     1381 ctttgtagcc tcaaagtgat ttttcttgct gttgctttca tctagctttt ttgcctgatg
     1441 tcttgtgttt gttggaaaag ctaggcttca aaaaaatgtc ttgcgctata ggtttaaatt
     1501 tgctatgcta taagtgtctt cagggcaggg tgtaattccc gaccggcggt gactagtgca
     1561 gctagaagtc cgcgagcgca agctgatgtg gtgtgattcc acaaccgaca gtaaagtctg
     1621 gaagagagaa gaccgggttt ttgagttgac tttttgcctg ctcatacgaa ggagcttctt
     1681 tcaatttgtc aaaattggag gaatttttta tgtcaaaaac acatcaactg gtgatggttg
     1741 ccattctttc agccatatcc ttttgcctga tgtttgtggg gttttccatt attccaggag
     1801 ccagcttttt aaagattgat tttagtatca ttccgatttt gttaggcttg gtcttgatgg
     1861 atctaaagca agctaacttg attttagcgg tgaggacctt gcttagacta gccttaaaca
     1921 atcatggcgt taatgatttg attggtatac cgatgaatgt tatagcagtt gcgcttttta
     1981 tcactgcctt tgccttgatt tggcatcgtc agaaagggct ggtcacctat gtactagcta
     2041 gtcttgtggg gacagggctg ttaacgcttg gtatggttgt catgaactat gtctttgcta
     2101 ttcccttata tgccaagttt gctggctttg atattaaagc ttttattggt actgctcgct
     2161 acatatttac aatggtcatt cctttcaacc ttttggaggg gctaatattt gcaattgtct
     2221 tttatttcgt gtatattgca ggtaaaccaa ttttagagag atatccgaat tcatatcatg
     2281 aaacataaac aacaacatct gctattgtct tcctttgcta tgctactatt tgtggtgctt
     2341 ggctatattg ttaaattttt tcccgaagac ctaacgtctt ttgatagtca gcttcggtta
     2401 gccctaagag gtcatctgcc tgaagggcta acccagtttt ttaaagggat cactgtagct
     2461 ggaaatgtta gtacacaggc agtgattgtt gttgttgctg tgctggcttt attggccttg
     2521 agctggagag ctgaggcctt atttgtccta tcaaatggtg tttttgcggc ccttttgatt
     2581 tgggtgctaa agctcttgta tcaaagacca agacccagca ttgagcattt ggtgcatgct
     2641 tctggctatt cttttccgag tggccattcg atgggaagcc ttttgattat tggaagtctg
     2701 ctgattattt gccatcaaag attgcagtca gcctccttac gctggctggt tgatatagcc
     2761 cttttggcct tgattttgct gataggcttg tcacgcattt atctgggagt gcattatcct
     2821 agcgatgtgt tggctggcta tgccttaggc tttggcatac ttcagctgct ttatcctttt
     2881 tatgatcaaa agcgctttga atggcgtttt cagctaaagc aaaagtaaat ccagtgatca
     2941 gtcagctgta tggcgcgtta cagatcagtt ctagaaaagc tagtgattga aggcaggtct
     3001 cttccagagg tcttcttcaa tcctttttag ttgccttgct ttggctcatc aatcagagaa
     3061 gtagcagcca attgagatct tctgctgtta atcgggggat ttgtgctaca atagaggcat
     3121 gacaaaaaga tatcagacct taaatgagta ttatcgtcgt ttatttggtg ctaaaatttt
     3181 caaggtgccc attgatgctg gctttgactg tcctaatcgt gatgggacag ttgctcatgg
     3241 tggctgcacc ttttgtaccg tttctggctc aggtgatgcg attgtggcgc ctgatgcacc
     3301 tatcagggaa caattttaca aagaaattga ttttatgcat cgcaagtggc ctgaggtcaa
     3361 tcagtatttg gtttattttc aaaattttac caatacgcat gataagctag aggttattcg
     3421 cgagcgctat gagcaagcaa tcaatgagcc tggcgttgtt ggtatcaata tcggaacaag
     3481 gcctgattgt ttgccagatg agacgattgc ttatttggct gagctatcag agcgcatgca
     3541 tgtgacagtg gagcttgggc tgcaaacaac ttatgaagcc acctcccagc tgattaatcg
     3601 ggcgcattct tatgacttgt ataaggaaac ggttcagcgt ctgaggcagt accctaacat
     3661 taacattgtg tctcacttga ttaatggctt gcctggtgaa acccatgaga tgatgatcga
     3721 aaacgttaga cgctgtgtca cagacaatga tattcaaggc attaagctgc atttgctgca
     3781 cctgatgacc aatacgcgta tgcaaagaga ctatcatgag ggacgcttgc agctcttgag
     3841 tcagaaggac tatgtatcga ttatctgtga tcagctagaa atcatacctg agcatatcat
     3901 tattcatcgc atcacaggtg atgcgcctag ggacatgctg attggtccca tgtggagcct
     3961 gaataaatgg gaggttttga atgcgattga cctagaaatg gaaagaagaa atagctggca
     4021 gggctgtaag cttaagggat aatcggggga agcaatgaaa caaagattga tagcaggaga
     4081 ggagctgagc ctaccacctg ttttaaaaaa actgttacaa aacagtttgg tttatgatag
     4141 cagtagctcg gcagaggcac gtgtttatgc tattgataaa gggcagggct attttctaaa
     4201 aacagccgct aaaggtaggc ttgccaagga ggccgcccta actcggtatt gtcatagtaa
     4261 gggcttagca acagaggtgc ttgattatat cagcggtgat caggattggc ttttaaccgc
     4321 aaaggtagca ggagaggacg ccagtcatat tgaatatttg tccgatccca agcgcttatg
     4381 tcgtatctta gttgatcata tgctaaagct gcatagcctg tctttgtctg attttcctgt
     4441 agctgacaaa acgctagcct atatcgaagc tgctgaggct ggttatcacc aagggcggtt
     4501 caatcagtgc tttttaccgc ctcagcaacg gtttcagtcc caggaggagg cttacaggcg
     4561 gattcaggag cttaagctct tgttacagca tgaaactctg attcatgggg atttttgttt
     4621 gccaaatatg atcttggatc ggtggcaatt tcagtccatg attgattggg gggaggcagg
     4681 aaaaagcgat cgacatattg atcttttttg gctgatctgg tcgcttcaat tcaatctaaa
     4741 aacagatcgg tataaagatt atgtgctaga ttgttacggc cgaaggcata ttgacttaga
     4801 catactagat ggtatcgcgg catttgaagt atttgcttag gaggataaga tgataaagcg
     4861 tcctattcat gtatcacatg aatttttaaa agaagttttg gataagcaga gtattgctgt
     4921 tgatgctact atgggaaatg gctatgacac tgccttttta gcaagtctgt cacaaagggt
     4981 ttatgctttt gatgtgcagc agcaggcact gaccaagaca caagagcgct tggagcagca
     5041 aggcttgact aatgcagagc ttattttagc tggacacgag caggtggatc aatatgttaa
     5101 ggagcccatt cgggcagcca tttttaatct gggctatcta cccaatgcag ataagtcgtt
     5161 gatcacaagg cctgagacga ccatattagc cctagctaaa atacttgatc ggcttgagct
     5221 aggtggacgg attgctatca tggtgtatta tggtcatgat ggcggtagta gggagaagga
     5281 agagcttttg gactatattg gtcagctcaa tcagcgccag gtaacagcaa tgctctatca
     5341 gccgatcaat cagatgaatc agccgccatt tttaatcatg ctggaaaaaa tagcagctac
     5401 tgattaagct tcagccagcc ttatgtcagg gcttagactg tctgtgattt ctcaggaaaa
     5461 agaaataaat cagcaatctt tggcgacaat tgtgatataa tgaagtagta tattatgttt
     5521 taggagttat attaatggaa gaccctgtga gtcagccttt attgattcag tttttattgt
     5581 tagtcattct aaccttgtta aatgcctttt tctcagccag tgagatggct ctggtatcct
     5641 taaatcgctc tcgtgtggag caaaaggctg ccgatgggga taagaggtat gatcgcttgc
     5701 tgcgtgtttt agagcagccc aataactttt tatcgaccat tcaggttggt attaccttta
     5761 ttagcctctt gtcaggggcg agcctgtcag cctctttagg gcaggttatt tctggctggt
     5821 taggtggttc tgcgaccgct caaacagctg gtagcattat ttctttggtg ttcttgacct
     5881 atgtctcgat tgttttggga gagttatacc ccaagcggat agctatgaat ctaaaagaca
     5941 agcttgctgt gatttctgcc ccagtgatca ttatcttggg gaaattggtt agtccctttg
     6001 tttggctctt atcggcgtcg acaaatttac tgagccggat taccccaatg acctttgatg
     6061 acgcagatga gcgcatgacg cgtgatgaga ttgagtacat gctgactaac agcgaggcaa
     6121 cgcttgatgc cgaagagatt gaaatgctgc aggggatttt ctcgcttgat gagatgatgg
     6181 cgcgtgaggt gatggttcca aggacagatg ccttcatgat tgacattaac gatgatacgc
     6241 tagacaatat caaggaaatc ctaaagcaga gcttctctcg tattccagtt tatgatgttg
     6301 acaaggacaa ggtgatcggc ttaattcata ccaaaaggct tttagaatca ggctttcgtc
     6361 agggctttga aaacatcagc atgagaaagc ttctgcagga gccgctcttt gtaccagaaa
     6421 cgatttttgt agatgatttg ttgaggcaat tgcgaaatac tcaaaaccag atggctatcc
     6481 tacttgatga gtacggaggg gttgcaggtt tggtgacgct tgaggatttg cttgaggaaa
     6541 tcgttggtga gattgatgat gagacagaca aggctgagca atttgttcat cacattgatg
     6601 acaacaccta tattgtcaca gggacaatga cgctcaacga ctttaacgag tattttgaca
     6661 cagaattaga aagtgatgat gtcgatacca tcgcgggctt ttatttgaca gggattggta
     6721 ccattccaag tcaaaaggag aaagagagct ttgcctgtga tagcaagcaa aagcatctgg
     6781 ttttggtcaa tgacaaagta aaggacggtc gtatcaccaa attgaaactt actatttcta
     6841 atatagaaca gaatattact gaagactagg cattgagctt agtctttttg atgaaacatg
     6901 atataatgaa aacgtaaaac catttacaag ggtgaaggag acacaatggt tgaagtagat
     6961 tatgggcaag taactggaat ggtgcattct acagaaagct ttggttctgt tgatggtccg
     7021 gggatacgtt ttatcatttt tttgcagggc tgcaagatgc gttgccagta ttgccataat
     7081 ccggacacct gggctatgga aaccaatcaa tctcaacgcc gaaccgttaa tgatgtccta
     7141 aaggaggctc tgcaatatag gcacttttgg gggaaaaagg gtggaatcac tgtgtcaggt
     7201 ggtgaggcta tgctgcaaat ggactttatc actgcgctct ttactgaggc caaaaagcta
     7261 ggtatccata caacgctaga tacctgtggc tttgcctatc gtccaacccc tgaataccat
     7321 gagctgttag aaacattatt agcagttact gatttgattt tgctggactt aaaggagatt
     7381 gacgaggagc agcataagct tgtcacccgt cagcccaata aaaatatcct gcagtttgct
     7441 cgctacctct ctgataggca ggtgcccgtc tggattcgcc atgtcttggt gcctggcttg
     7501 acagacattg atgatcactt ggtacgctta gatgcgtttg tcaagacctt gagaaatgtc
     7561 gacaagtttg aggtactccc ttatcatacg atgggagagt tcaaatggcg cgagttaggg
     7621 attccatacc agcttgaggg cgttaagcca ccaaccaagg agcgggtgga gaatgccaaa
     7681 aagctgctgc atacagaatc ctatactgaa tacatgaacc gtattcatca atcataggct
     7741 aagctagagt tgggaaatgc ccagcttttt ttggccccat gtcaactgta gtgggtgact
     7801 gataactaag cacgagacga agctcgtttt ctcttgtgtg atgtgcaaag cgaggtaaat
     7861 gggctctata atttctgtag tgggtaaatc caccatggaa attatagagc cgtttttttg
     7921 ctgatgaagc ggctggcttg atgagacctt cagtgttttt aagcgagctc agacacgtgc
     7981 caaaaagtaa tccttgaagc attaaaccaa tcaaggacag tgtattgtcc ccaaatagct
     8041 gaatagctca ttatagaagg cattgctttt tggactggct tgcctgttct tgtgtgtttg
     8101 acaggactct ttaatacctg agattctgtg cccttatgcc ctttagactc ttggcctgtg
     8161 actggggaat cttctttgat tttagagcct atttctgcta caataagatg aataaagaga
     8221 atgaggtaga aactttatgt caaaactatt agtttttggt catcaaaatc cagatactga
     8281 tgccatcgca tcatcgtatg cttttgacta cttagcaaaa aaagcctttg atttggatac
     8341 ggaggtagtc gctctgggtg acccaaatga agaaacagcc tttgcccttg actattttgg
     8401 ggtatcagca ccaagagtgg tgacatcagc aaaagcagag ggtgctagtc atgttattct
     8461 aacagaccat aacgaatttc cacagtctat ttcggatatt cgtgaggttg aggtgtatgg
     8521 tattgttgac caccatcggg tggctaattt tgagacagca aatccgcttt atatgcgtgt
     8581 cgaacctgtt ggctctgcct catctattgt ttaccgcctg ttcaaggaaa atagggttga
     8641 tgtgccaaag gacattgcag gcatgctttt gtctggcttg atttctgata ccttgctgtt
     8701 aaaatcacca acaacgcatg cttcagatca tcgtgttgct gcggaattag cagagttagc
     8761 aggagttaag ctagaggaat acggtatggc tatgctaaag gccggaacaa accttgcaag
     8821 taaatcagaa gcagaattga ttgatattga tgctaagacc tttgaattaa atggcaacgc
     8881 agttcgtgta gcccaggtca ataccgttga cattgcagag gtgttagagc gcaaggaggc
     8941 tattgaggcc gctattagag aggtgatggc aagtgagggc tattctgatt ttgtcttgat
     9001 gattacagat attgttaatt caaattcaga gattttggcg cttggtgcga atatggataa
     9061 ggttgaggca gcctttagct ttaagcttga ggataatcat gctttcctag caggtgctgt
     9121 atctcgtaaa aagcaggttg tccctcaatt aactgaaagc tttggagcat agagcttgcc
     9181 tgtagagggg tgttgatttt tatcagcagc cctttggtct ttttgctata atagtagtat
     9241 gattaccatt tttaaccctg ataaattaac gcgtcagcct ttttttcaag accttattca
     9301 ttacctcaat cagcatgatg acgtaaccct gcgtcacatt aagcaggcct tttctcatgt
     9361 taaggggatt gataaggcgc ttgaagctta cattcaggct ggctatatct gtcgaaaaaa
     9421 cagacgctac tatctgtgtc tgcccttgct agatgacctg cagcaggtga cattagaaga
     9481 tctaatcttt gtggataggg catcagatct atatgaagct ttgatggcct tggtgtttga
     9541 gacagtgctg tctaatcaga ccaatcaggt tttgatcaag gaaaaaacaa ccattgaccg
     9601 agataagctg acgcttgcca attattttta ccgcttaaga agaggggaag ccctatctga
     9661 tgagcaatta aggctctatg ccctattagg tgatgtgaat caggactatg ccttgaagta
     9721 catgaccagc tttcttctaa aatttgctag aaaagagatt gttatgcaaa agcggacaga
     9781 tatttttgtg aatgccttgg agcttctagg ctatattgaa aaagtagagg ccactaaata
     9841 ctgcctgaag ctggcttttg ataaggagca gctgattttc tacgctgatt aagagttgac
     9901 ttgatgaata aaaaatggct tagacccaca ctgtaaaaca gttgagtcta agccatttat
     9961 gcttgctgag ccctttaagc tatgcagcag aggctcttat gtcattttga ccatcagata
    10021 gagaaaatag gatgcaccaa taattgagac aagaataccg gttggtatat tgctgccgac
    10081 gagatagact cgtccgatag tgtcagccaa gagaagcaga atcatgccga tgaaaaggct
    10141 gacaggcagg cttaatcggt gatcagctcc cactagtcgt ttgctggtat ggcctgctat
    10201 cagaccaata aaggtgatgt ttccgaccaa aataacactt agggctgaga gaatcgcaga
    10261 tagtgcaaga acaatggtac ggtactgatg gagcttgaag cctagagcca tgcttgcttc
    10321 atcatttaat gccatgatgt tgagcttata ggcttgacta aaggctagca gccaagtgat
    10381 ccccaataag ggagcaacaa tgcttagctt ggaccaatca tcgcctgtta gctgcccgct
    10441 tagccaatga atcacataat ccaccttata acggttcaca ttgccgacaa aggcaatcat
    10501 caggctagat agcatggttg atagccctac gccagtgaca atcagccgaa taggatcaat
    10561 atggccatga cgaagtgaga gcaggtagac caagacaatg gttgccattg ccccggatat
    10621 ggtcataagc ggcagccctt gcctgctggt cagactgtta ctagtgctgt aggatatgac
    10681 aagggtaata gccataccag caccagcatt aatgcctagt atgccagaat ctgccagatg
    10741 atttcgcgtt aagctttgca gcattaagcc agaaagggcc agtgagccgc caccgataca
    10801 ggcagctaaa attcttggga gtctaatgtt ggtgatgatc aaggccatat cagcagtgga
    10861 tttaccaaaa agcaccctga cgacctccaa tggtgacatg ctagattccc caatagacaa
    10921 ggaaataatc atcaaacaga ccagtccaga gattagtcct agaaataatg ggacgtgtct
    10981 tttagtagct gtcaaaagcg acctcctttt ctaactagcc ataaaaagca gggcagccca
    11041 ataaagctga tcaaagcaga tagcggtgtt tcataggggg gattgatatt ccgacaggca
    11101 aagtctaccc aaagcataaa gctggctcca agaagagtag ctagcggcag gatccagcgg
    11161 taatccttag cagtgactaa tgtgatggca tgagggataa tcaagccgac aaaggaaatg
    11221 ctgccggcta ctgctacagc agcagaagac agaagcagca caagtccaat aaagataagg
    11281 ctaatcaaga aggtgcgttg ccctagggcc ttggcctgct cttgacttaa gcttaaaatg
    11341 gtcaaatgat aggctagcag ataagatagg gctaagccac agatgatgag tggcgcaaca
    11401 tagctaacca tctgccaatt gaccccgatc aatcctcccg cctgccagcc aataatggca
    11461 ttggctaggt gacaataagt tgttattcct tgtccgatag ctgacagtag catagatatc
    11521 atcgctcctg ctaaaataag cctcatttga gtgtagccct taccagcttg ataggctagg
    11581 ctgagaatta atagggtcgc taagagtgac cctagcaagg aaagtaatat aattgtcgaa
    11641 taatgaagat gaggggaaaa agcatagccg atgactaatg ccagcccagc tccagagttg
    11701 attcccagta agccaggctc ggcaatggga tttctggtaa tgccttgcat gatagctcct
    11761 gaaacagcaa gtgcagcacc aactagagct gctaaaatca agcggggcag gcgaatgtcc
    11821 aaaataatgc tggccttttg accctggtcc tgctttccaa gtagaatatg atagagctcc
    11881 tgatgtgata gtgacacagc cccaaacctc agactgcagt aaatggcaag cactagagtt
    11941 aagctgataa aggttaagat cagccaagga ggagctgctt tagctagttt aggcttagta
    12001 tgatgttgag ctgtcatctt aagtttttat tgacttgcac cagttgagag gatagccttt
    12061 tttagaacct caagctggtg ctccagtgac agtgggtctg tgaagtaaaa gacattagcg
    12121 ttgaccttga tgacatgatt gttggtcaca gcagggatct gctgccaaag gtcgctctca
    12181 tataaggctg agccggtttg gtcatcctca gcagcaacaa tcacataatc accaatataa
    12241 tctggtagaa cctcctgtga taaggacaga tagccctgct taaacacctc ttttttcacc
    12301 ttttcgggag catcataatg taaggcctga tgaataattt caccacctct tccccagtcc
    12361 ttaccaaaaa ggtaaatttc cttttcatag agccccatga ttgtaaaggt agcagctgat
    12421 ccggtgactt gttttatttc tttttcatag tcacttgttt tttgtttcca gtcggccaac
    12481 cattggtcag tttccttttc cttgttaaaa atacggccaa aatcagaaaa cacctgcaaa
    12541 taatcacgct tgcggtattc aatggagatt agtggtgcga tttttgctag ctggtcaatg
    12601 ttttcttctg ttgagccaac aacaatgaga tcaggctcta gtgctgtaat agcctctagg
    12661 tcagtagctg ccacctgctt ggcttgagta atgctttttg ttaaaacagg gttctttttg
    12721 tcgtaggagg tgacaccgac cagatgaagg tctaattttg ccaagtaacc agtatatgta
    12781 gctgctaagc taaccacgcg ctttggcttg acaggaatgt caccataata ggtcactcca
    12841 gcaatttttg gcttgtggga taggcttgct ttgctggtgc tttcttgttg cttgctttga
    12901 cttgagcagg cgactaatgt aaaagctgtc acaaaaacag ttaaaataag cagtagtttt
    12961 ttcatgtatt ctattctcct agaataaatt tatatcagct gataggtcag caatgtaggg
    13021 caatgataga gaggatcagt gacgagctga gcctttactt gaaaaatgtc ttgaatcatc
    13081 tctggcgtca tcacctggtt gacctctcca gaatatttga tatgtccatt tttcatggcg
    13141 atcagatgat ccgagtagcg tgctgaaaga tttaaatcat gaaggaccat cacgattgtt
    13201 tttccagaga cctgattgag ctcctttagt aattctaaaa tatcgagctg atgattcata
    13261 tctaagtagg ttgttggctc atctagaaaa ataatatcag tatcctgtgc taaggccata
    13321 gcaatccagg ccctttgacg ttggccgcct gacagggcat caacagcctg atgagcatag
    13381 ggtgccatgc ttgtgacctc cattgcccag caaatcttat ccttatcagc ttgactgagt
    13441 tgtcctaggt aggattggtg gggataacgc ccataagaaa ccagctcata gacagtagct
    13501 gtagtagctt cttgcagctg aggtaaaact gctagtgttc tggcaacgtc cttggttgct
    13561 agtctagcaa tggcttgtcc atctaagaga acctgccctg ctttgagtgg caatagtcgt
    13621 gccagagtct ttaaaagggt tgacttccca cagccattag caccgatgat ggttgttacc
    13681 tttccttcgg gaatagtgac agataagttg ctgatgataa gcgattgatc atagccagct
    13741 gaaatcctct cagcactgat tgttgacatg gtttttctcc tttctaatag tcaagcaaag
    13801 ccagctagca aaattctaag gggctgatag cctatgaaat gctagtcgct tttttggtct
    13861 gactataata gtgcgctttc tcttaaaagc tatcccatta tagcatagaa aaaaggccta
    13921 aaaaagcctt tcagaatcta attactgagt ttatgctaaa aaaggagcca gcttagaatc
    13981 attatcagta atcttaagaa ttattactgt ttagcctgtt agaccagtct ataggtagct
    14041 ctttgcaatc gctaaatcac ctgcataggc agtcttttgt cccttgacaa tctgataagc
    14101 atcagccccc ttgccagcaa taatgagtgc atcctgctca ttctgacagc gctccatacc
    14161 agtcttgatt gcttctttac ggtcaatgat aatatcaacc tcgcggtgaa tatagctagc
    14221 aatctcctct gaaatcagct gtgggtcctc aaaattagga tcatcagcag tcagaataat
    14281 acgaacattg gggtgctggt tgatgacttg cccaaaatca gcccgacggc tctcgccttt
    14341 attgcccggt gctcctagaa tcaagtaaat ctggcctttc tggtactctt cgacaacaga
    14401 taggagcttt tcaaggctat caccgttatg tgcataatca acaaatacct tggcctgatt
    14461 ggtcatggtt aagacctcca tgcggccagg gacgtttgtc ttagcaatgc cttggcggat
    14521 atcctctagg cttgccccca gtcgaagaca ggctagtcca gcagccatag cattttcttg
    14581 attgaagctg ccaattaatt gaatcgcata gtctccagct accttgccgg ctgcttgaaa
    14641 tgagaaggcc tgccgctgca gcagcctatt gcaagcccct ttgccataaa aatcatgagg
    14701 cttatcagcc acctgctctg ctaggatatt aaaatgctcc ataccgctat tgaccacaac
    14761 agctcggcta ttttccatta agagccgctt atggtaaaaa taatcctcaa agcttgggtg
    14821 ctcgattggt ccgatgtgat cggggctaat attaagaaag acaccgacat caaaggttaa
    14881 gccgtagata cgcccgacca agtaggcttg actagagacc tccatcacca aatgcgtcat
    14941 gccattagcc acacactgag ccatcatcgc aaataaatca agactttcag gtgtggttaa
    15001 ctgcgattta aaaaagtgtt ggccatctaa ggtcgtgttc attgtagaga gcagggcagg
    15061 cttatgagat tcctttagca tatgataggc aaagtaggca gcagttgtct tgccctttgt
    15121 tccggtgaag gctaatagct tgagcttatt ttgtgggtaa tcataaaagg ccatcgcagc
    15181 taggctcata gcgtgcttaa tattgttaac aagaataaca gggatcccta cctgatagtc
    15241 aatctctgaa acatagagtc ttagtccctt ggcaatggcc tgtctcaaaa agtcagcctt
    15301 aaaagctgat cccttagcaa aaaagagcgt ctgctcatct gcttgtctgc tgtcgtagct
    15361 aaggctgtca aactgtagac cgctatagtt aaagtggtag ccgtcttgat caagaacctc
    15421 tcggaaatta tggtcctttt ttaaaatggt taataagtgc tcaattgtta tcatagcctt
    15481 attttatcct taatgttctt gttttacaag tcacaagcaa aagtttataa taaagctata
    15541 aaaactagga agaacggata tgtcgacaga aaaaaaacaa ttgacacaag aacagctgat
    15601 ggttcaggga gcagcctggt ccaccgcagg taattttatt agccgacttt taggcgttct
    15661 atatattatt ccatggtaca tatggatggg gcagtatgcg atacaggcaa atgcgctctt
    15721 taatatggga tacaatgtgt atgcctattt tttgttgatt tcgacaacag ggctaaatgt
    15781 tgccattgct aagcaggtcg ctaagtacaa ctcgatggga cagcaagagc atagctatca
    15841 gctcattcga agcactctaa aggttatgct ggtattaggc ttgattttct cagtgctgat
    15901 gtatctggga tctccgctct ttgctcgctt gtccggtggt gatgagaccc ttgtcccgat
    15961 tatgcatagc ttatcattag ctgtttttgt ttttccagtg atgagcgtga ttagggggat
    16021 ttttcagggc tataaggaga ttaagcccta tgctcttagc caaattgctg agcagctggt
    16081 tcgtgtgatc tggatgcttc taacaacctt tttcatcatg aaaatggggt ctaaggacta
    16141 tattgcagct gttacgcagt ccacctttgc tgcttttatt ggaatgatag ccagtatggc
    16201 ggtgctcttt tattatttct ggacgcaggg ccttttaaag gctattttta ccaagacaga
    16261 gcatgcgatt cctattgaca tcaagggctt gcttattgaa acgttaaagg agtcgattcc
    16321 ctttattatt acaggaagtg cgattcaggc ctttcagctc cttgatcagt ggacctttgt
    16381 caatacgatg actctgttta ccagctacac gcgttctcag ctctgggtgc tgtttgggta
    16441 ttttaacgcc aaccctgcta aaatcaccat ggtgctcatt gcagtagccg cttcaattgg
    16501 tagtgttggt attgccttat tgacagaaaa ttacattaaa aaggacatgc gagcagcagc
    16561 gcgcctgatc attaacaaca ttgaaatgct gctgatgttt ttattgcctg ctctgacagg
    16621 agctattata ctggcaaggc ctctttatac ggttttttac ggtagtagcg agggacaggc
    16681 tgttaggctg tttgttgctg tgctttgcct taccctattg atggccttgt atacgctttt
    16741 ttctccgatg ctgcaggccc tgtttgaaaa ccgtaaggcc atctattatt ttgcttatgg
    16801 tgtttttgtc aagctggttt tgcaggttcc tttgatctat ctgtttcatg cttatggtcc
    16861 tttgttagct acgacccttg gcttgctagt gcctatctat ctcatgtacc gtcgtctaca
    16921 tcaggtcaca cgatttaacc gtaagctgct gcataagcgt atattactaa cggtgattga
    16981 gacagcattg atgggcctga ttgtgctact agctaactgg tttttgggct atttgtttaa
    17041 gccgacaggc agattgacta gcctgcttta cttagtgatt attggtggct tgggaatggg
    17101 tgtttacgcc tacatgacgt tattgacgcg tcagctggac aaattaattg gcagcagagc
    17161 agctaggtat cgccaaaaat tgggactttg acacccaaga tcaaggcagc tgaagcaggc
    17221 agctagctga tcagattctt gcttttatca tttcaaccgg atctgaaaaa agtaagcaag
    17281 gttttcaatt ttttggtata atagcaaaag tgtaaaaaat aaagaaggaa gtacgtcatc
    17341 atgggaaaat gtcaggttat ttcgcatcca cttattcagc ataagctatc aatcctgcgt
    17401 cgtcaggata cctcaaccaa ggattttaga gagctggtca atgaaattgc aatgcttatg
    17461 ggctacgagg tttctcgtga cttgccatta gaggatgttg agattcaaac accggttgcc
    17521 aagacggttc aaaagcagtt agcaggtaaa aaattagcaa ttgttccgat tcttagagct
    17581 ggtattggta tggtggatgg ctttcttagt cttgtgccag ctgccaaggt tggtcacatc
    17641 ggtatgtatc gtaacgagga gaccttggag ccggttgaat atttggtgaa gctgccagag
    17701 gatattgatc agcgccaaat ttttattgtt gatccgatgc tggctactgg cggctctgct
    17761 attcttgcag tggattcact gaaaaagcgt ggggctgcta atattaagtt tgtgtgtctg
    17821 gtagcagcac cagaaggggt taaaaagctt caggaggctc acccagatgt tgacatttat
    17881 accgcagccc ttgatgaaag attaaatgat catggctaca ttgttcctgg tcttggagat
    17941 gctggtgatc gcttatttgg taccaagtaa aaggctacag gctttggttg tgctaggctc
    18001 tgcttgctag aggctagcct gctaaagcta ataagacttt ctagtttagg ctggaaggtt
    18061 tttaaaagca agtttatcat ttgacctttt ttgaccaaga gattataata aggtcaatca
    18121 ttataaaaag atgtgtttga ctgcctgtca ctgcatgagg cagagtggtg ttagacagtc
    18181 acgatagatt ggagattttt atgattcctg tagttattga acaaaccagt cgtggagagc
    18241 gttcttatga catttattca cgtctgttaa aggaccgtat tatcatgctg actggtccag
    18301 tagaggataa tatggcaaac tctgttattg cgcagctctt gtttttagat gcccaagaca
    18361 acacaaaaga tatttacctc tatgtgaata ccccaggagg ctctgtatca gctggtttag
    18421 ctattgttga tacgatgaac tttattaagg cagatgtgca aaccattgtt atgggtatgg
    18481 ctgcttctat gggaaccgtt attgcttcat caggtgcaaa gggcaagcgc tttatgcttc
    18541 caaatgcaga atatatgatt caccagccta tgggaggcac aggaggtggt acgcagcaga
    18601 cggatatggc cattgctgct gagcatttat taaagacacg tcaccgcctg gaaaagattt
    18661 tggcacaaaa tgccggtaaa acgatcaaac aaatccataa ggacgctgag cgtgattatt
    18721 ggatgagcgc agaagaaacc ctagcctatg gctttattga tgaaatcatg gaaaataatg
    18781 agctagctta gagagcttag taaaatagct taacagcttc tgaaacaaat tgtttcaggg
    18841 gctttttgca tgctaaagag ggctatcttc cttaaaatta tggtataatt aacctatgct
    18901 aatcataaat gaagaattgt ttgccattga aaaggctatt gagcagctgg ttcaggatat
    18961 taggacaagc agccagtatc aggcctatgc cttggctaaa aaggcttttg aggcagattt
    19021 ggccctacag accgagttag ccttatttga ggagcttaag caggattatg agcttaggca
    19081 ggacttgctt aagttgtgtc cagatgctag agcgttgcgc tgccaattac ttcatcaaaa
    19141 gcgccagctt gacctgcatc cattggttgc tgatctgcgc ttggcacagg ttgatttgca
    19201 ggaggttttg gcgacgattt cgacagctat tgcagaagca gtgtctgagg atattcttgt
    19261 cgacacagga cttcccttgg cgacaaatag acctcgacat gagcttggac cgtatcaaaa
    19321 tataaaagaa aagagtacct aaatgtttca aaaacagcag agaattgggc tggttatcta
    19381 cctgtattac aatcgagacg ctagaaaagt gatgaaatat ggtgacttgt actaccattc
    19441 caggcgttct cgataccttg ttatttacat caataaagag gacatggaag aaaagctaaa
    19501 ggacattagt cggctaacat ttgtcaaaga ggtgaaggta tcagcctttg atgacattga
    19561 ttgtgatttt gttgggaatt tacatcgtga gcctctagag cctcaagccc tacctgagca
    19621 gggctaagta ggcctgatcc tgtcttatat agcatgtctt agctcatcaa ttgctcaaag
    19681 ctgatggatc agccctgctg gcttgcttag gcaaagaaaa taagagctga gacgattgtc
    19741 atttatcgag tggctgctca taggctttga ggtgtgaggc acaagtctta ggctgctgct
    19801 ttgagggctg gctttttatt cctatcgcct aaaaggcagc acaaaaaggc ttttttctga
    19861 tctggcactg cccaatgaat tggcagtgct ttttcaggca aattttggta aaatagaggt
    19921 aacgataaac aaaggaataa agatgactag aggaaaatta ataacgtttg aaggtccaga
    19981 cggagcagga aaaacaacgg tgctggaaag actggtgcca ctcttacagg cagctctagg
    20041 acaaaccatt gtaacaacga gagagcctgg aggcgttgcg attgctgaga agattcgtca
    20101 gctgatctta gatgtcagtc acacgaccat ggacgataaa acagagctgc tgctctatat
    20161 tgcagcaaga aggcagcatt tggttgaaaa gatcatgcca gctcttgagt caggacactt
    20221 ggttttggtg gatcgtttta ttgacagttc agttgcttat caaggcgccg gaagagggct
    20281 ggataagcaa gccattcaat ggctcaatca ttttgcaaca gatggtgttg accctgattt
    20341 aaccctgtat tttgatgtgc cctcagagct tggattggca aggattgcac aaaatactga
    20401 gcgagagatc aatcgtcttg atcttgagca attagatttg caccagcgtg ttcgtaaggg
    20461 ctatctggag ctggctttgg aaaatcccca gcgtattgtc aagattgatg catcacagga
    20521 cttagaaagc gttgtgtcag cggctttagc tgccattatc acacacagtc aagcatagca
    20581 ggaggttagg aatggatttg gctcaaaagg ctcctagggt ctatcaggcc tttcaagaga
    20641 ttttgcaaaa aaaacgtcta aatcatgcct acctcttttc aggtgatttt gccaattttg
    20701 acatggctct ttttttagcc aagactcttt tttgcgaaca aaaaagaggc aatgctcctt
    20761 gtcatcactg tcgtgcttgc cagctgattg agcacaatga cttttcagat gtcaccatct
    20821 tagagcctgt cggtcagctt atcaagactg ataccgtcaa agaaatgatg acaaattttt
    20881 cgcagaccgg ctatgagggc aggcggcagg tttttatcat taaggattgt gataagatgc
    20941 atgtcaatgc agctaacagc attttaaaat atatagaaga gccacaaggg gattgctata
    21001 tgtttttact aacgaatgat gacaatcagg tcctaccaac gatcaagagc cgtacacagg
    21061 tttttcactt tccaaaagat gagcactacc tctctgagct ggcccaaaaa aaggggcttt
    21121 tgaaacatca agcagacctc ttagccagat tagcagccaa tgcccagcag cttaccgctt
    21181 tttctgaaaa caccaggctg ttggagctga tggcgcaggc tgagcgtttt gtttccatct
    21241 ggtttcagga taaggaacag gcttatctgg agcttaatcg cttggttcag ctagcagagg
    21301 aaaaagagga gcaggacatg gcactaactc ttttaacctt aatcttggcg aaggactaca
    21361 gtcgacaaaa tgcttttacc tatctggagg ctgtttatca ggctagactt atgtggcaaa
    21421 gcaatgtcag ctttcaaaat acgttagaat atatggtgat ttcatgataa gtacgattgg
    21481 aattaaatat tgtgacacct gctctgtcag gtacgttcaa accgatcagg cctttcctgt
    21541 gcaaaccaag cttgtcatat ctgatggcaa gggcagtcga ttggcagtgg tcaattctcc
    21601 gataaaaagc ttttgtaagg acgacctgcc aaaggatatg ccctctgttt tgagacctgc
    21661 caatgacatg gactacaagg cttaccagca aaaccttcag ctagcagccc agtcaaagca
    21721 aaaagtagca gagatgattg acagaaatgg cttagacatg accttggttg acattgtttt
    21781 ctcccttgag agacgttatg ttttgattac ctttaccgct caggagcgtg ttgattttcg
    21841 ccagctcctc aaggatttgg ctgcctattt caagacaagg attgagctgc gtcagattaa
    21901 tagtcgtgag gaggcaaggg tttatggagg gctgggtccc tgtggtcgcc cactatgctg
    21961 ttcaagcttt ttaggagagt ttcctccagt ctcaatcaaa atgctaaaac atcaagggct
    22021 gtccttgcat tcggcaaagt ctttgggctg ctgcggtcgc ttgctgtgct gcctacaata
    22081 tgaggacgat ttttatcaag aaagtaagaa aaaatttcct gattatggta ctatagtaag
    22141 aacagcgcag ggaccaggtg aggttgcagg aattgatctt tttacagata ccattcaggt
    22201 tcgctttaag gaccagctgg ccttggtaac ctatgcttta gaggaggtta aagttagtga
    22261 ataaaaaaga actgtttgac gcttttgatg gcttttcaca aaacctgatg gtgactttag
    22321 ctgaaattga agcaatgaaa aagcaggtcc aaggactcgt agaggaaaat actatcctta
    22381 ggcttgaaaa caccaaatta cgtgagcgct tgagtcaatt ggagcacgaa aatctggcca
    22441 agacctcttc taagcagggc aaggaccact tggagggcat ttatgatgag ggctttcata
    22501 tctgcaattt tttctatggg caacgtcgtg aaaatgatga agagtgtatg ttttgtcgag
    22561 agctattaga tagaaagtag agtcatgcaa atccaaaaga gcttcaagga agaaaaagag
    22621 tcaggggttc tctatctggt gcctacccct attggtaacc tagaggatat gacctttaga
    22681 gcggtcaatg ttctaaaaga ggtggatatt atctgtgcag aggatacgag aaatactggt
    22741 ctgttgctca agcattttgg gataaagaca aagcaggtaa gctttcatga gcataatgct
    22801 tatgataaaa ttccagattt gctggacctg ttgttggctg gaaggtcatt ggctcaggtc
    22861 tccgatgctg gtatgccctc tatttcagat cctggtcatg agctagtcag agcagctatt
    22921 gatcgagata ttactgttgt tgctttgccg ggtgcttctg cgggcattac cggcctcatt
    22981 gctagtggct tggcgcccca gccccatctg ttttatggct ttttgccaag aaaagctggg
    23041 cagcaaaggg catttttgat gactaaggca gattatccag agactcaaat cttttatgaa
    23101 tctccttatc gtgttaagga tacgctaaca aacctgctgg cctgctatgg ggatcgccag
    23161 gtggtgctgg tgagagagtt aaccaagctt tttgaggaat accagcgtgg tcagatttca
    23221 gaggtcttga cctatctagc agaccatcca ctcaagggtg agtgtctatt gattgtggca
    23281 ggtgccaatc aagctgacgc atcagagcct gctgaggatt tggatctgct agcacttgtt
    23341 caacaggcta ttgctgctgg catgaagcct aatcaggcga tcaagacaat cgccaaagac
    23401 tataaggtga atcgccaaga gctctatcag caatttcatg ggcttggcta gactggcttt
    23461 taatccggac tagtcgcctg attgagagaa tctctagtag gccaagcaaa ggagaggtac
    23521 tcaagtaagg gctaatagct gtcttttgca cttctgagaa ttgtcattaa tgtaagcaga
    23581 tagatttgtc tgcacactaa gagagctagt cagttctctt tttttggctt cttgtcaact
    23641 ttaggggggt gactgataac tagtacctag tgaggaccag actggtgctt tttttgtgtt
    23701 gttaatagca atgagaagct tgcttttaat gtttttaagg ttcctaaagc cacaggcttg
    23761 tcgcttcacg ccttccctta atggtcactt tgcagtctta aacgaaaaaa atgctcccat
    23821 ttaggacgtt tcaacgactg tttaggatat ggaggaatgt tttacaaaaa aagcgttata
    23881 ctaaatatgt caaggttgca actggacaac atcgattttt agggagtatt tgcaatcaat
    23941 acaataattt gacgtaatgg ctacagaaat gcttgctagc tttgaaggag gaaaaaataa
    24001 ttgggctgcc aatgtgtcag gtgtgattgg agcaggaagt gcaggcgcag cacttggatt
    24061 tccagtatgt ggagtagctt gtggatctat tggtgtcaca ggaggctttt agaaatgaga
    24121 aaaacagaaa gattctgagt ttggaacctt gttttaggag gataatagaa atggaacatt
    24181 atagagcatt agcaataagt gaaatgcaag atatttcagg aggaaatgca gcaggtaatg
    24241 ctgttatcgg gggattagga ggtctcaaga caggaattac attttgcaaa atacctcatc
    24301 cggtgctaaa aggagtatgt atagacggct ttactgcttt aggagcatgc ttggcatata
    24361 aggtaaatta gatgttattg attacttttt caggtcttta tgctttaatt tttatctata
    24421 tactggttga cagtgctaag aggggcaaag aaggggcttc ttactttatt tttttaattt
    24481 tttatttctt atcgactact ataagcaatg taaatcttat atcccttgtg accttactat
    24541 gttttttagc tatttatata gaaaaaaggt aaattaagtt ttgtatggtt cgtttagata
    24601 ctttttcaac agtttaggga gtatttgtaa tcaatcagaa atgctggtaa atgctgaagg
    24661 tcggctatgg atacgcactg gaggtgtaag aaacatcgat gctggtactt aaaagtagct
    24721 tggtgtcaga tagtgagtgg cagtgagggt tcataccaaa atggtcatta aatagtgatt
    24781 gatagctggt gaaggcaata aataagacca aaataattct tctcattcta ccaataattg
    24841 ctttttttat tcggctgggt gatctattct tggttgaggg atagcaaagt ccttaccttt
    24901 accttatggg ctctttgggg gttatcatat aagggagtaa gcctggttaa gagagtttta
    24961 gcgctttaaa attgtaaaat cagattattt aatgtatact agaggaaata agatgaataa
    25021 agacggaagg tcaatacaat gataatcaaa aaactttcag taatagctct tacgagtcta
    25081 tccttaatca gcctatcagc ttgtcgtcaa cagaatcagg ctctaggtca aaatggcagt
    25141 gctcagaatc ataggaaggc aagtgtttca gaggacaagg ccaaggaact tgcctttaag
    25201 gacgcctcaa tcacagcagc tgacgctcaa aggctcaagc tgacgaaaga aacagacgat
    25261 ggtagagtgg tctatgatat tgagtttgat gctaaggatc aggagtatag ctataccatt
    25321 gacgctaata ccggtgagat cctagaaaaa tcctctgagc caatcactga ggctcctgct
    25381 tcagctcaag cagctggtgg tcaggctgat caagcagctg gcatttcaga ggacaaggcc
    25441 aaggagcttg cttttaagga cgcctcaatc acagcagctg acgcccaaag gctaaagctg
    25501 acgaaagaaa cagacgacgg tagggtggtc tacgatattg agtttgacgc caaggatcag
    25561 gagtacagct atactattga tgctaatagt ggagatattt tagaaaagtc ctctgagcct
    25621 gtttacgatt aaaaagctat caccgcttat gtgataaaag cctgtaacat tcctaagcct
    25681 ttatatgcta aaagggctta ggttttttgt tgttccttgt tgtgcctgat agagctggag
    25741 cttgttggca gccatttagg cgctagccta tagcccgcct ttgttgctgg tatttggctg
    25801 tgataagggc tgtttagttg aaatgatagg cattatcagc ttaggatttg gcagagtgat
    25861 acttttatga ctagaaggat aggctatggg ctgtaaatgt tgtataatag agtagaaagc
    25921 gcttgctatg attgagagag cctatctcag cagcgataga atggaggaca catgggaact
    25981 gaaacctata ttatggctat tgatcagggc acaacgagct ctcgtgccat tattttcaat
    26041 aagaaaggag aagcgctggt tagtagtcaa aaggaatttc cacagctttt tccacaggct
    26101 ggctgggttg agcacaacgc caatcacatt tggaatttgg tgcagtctgt tattgcagac
    26161 gcctttatcg agtctggtat aaagccagag caaatagaag ctataggcat taccaaccag
    26221 cgtgaaacaa cggtagtctg ggacaaacag acaggtctgc ccatctataa tgctattgtg
    26281 tggcaatcta gacaaacagc ctccattgca gagcagctaa agcgtgatgg ctataccaaa
    26341 atgatccatg aaaaaacagg cctggttata gatgcttatt tttctgcgac caagctcaga
    26401 tggcttcttg atcatgttcc gggggctcaa gagcgagctg aaaggggaga attattattt
    26461 ggcacgattg acacctggct ggtttggaag ctaacggacg gggcggtaca tgtgacggat
    26521 tattctaatg cagcacgtac catgctatac aatatcaaag agctaaaatg ggacgatgag
    26581 atattggcct tgctgaatat ccctaaggcc atgcttcctg aggtcaggtc taattcggaa
    26641 atttatggta aaacggcttc ttttcatttt tacggaggag aggtagctat tgctggcatg
    26701 gcaggtgatc agcaggcagc cctatttggg caactggcct ttgagcctgg tatggtaaaa
    26761 aatacctatg gcacaggctc ttttatcatc atgaatactg gtcaagaggc tcaattatcc
    26821 agcagcaacc tgctaacaac gattggatat ggtattaatg gcaaggttta ttatgcctta
    26881 gaagggtcta tctttattgc tggctctgct gtgcaatggc tacgagatgg cttgcgaatg
    26941 ataaaaacct cttttgagtc tgaacagcta gccttggctt caaccaatgc tgatgaggta
    27001 tatgttgtac cagcctttac aggtcttggc gctccttatt gggattccaa tgcacgcggc
    27061 tcagtatttg gcttaacgcg tggaacaaca aaagaggatt ttgttaaggc taccctacag
    27121 tctattgctt atcaggtcag agatgtgatt gataccatgc aggtggactc agggatcact
    27181 atccagcaat tacgtgttga tggcggagcg gctatgaata acatgctcat gcagtttcag
    27241 gcagatattt tagggattga tattgctcgt gctgaaaatc ttgaaaccac agctctagga
    27301 gcagcctttt tagccgggct tgctgtaggc tactggaagg acatggagac gctaaagcaa
    27361 ttaaatgcta caggtcagct gtttaaagca agcatgagtg agtctcgccg agaaaagtta
    27421 tatcaaggct ggaaaagagc tgtcaaagcc acacagtttt ttgcagagga gctgtaagaa
    27481 tcaagccttt taaagaaaca gagtcccata gctaggtcta gttttgaaca ctagactgtg
    27541 tgatacttgg tcttttatat cctaagagtg acttttataa tgataatgta gacggtaaac
    27601 agcgtcatgc tgttcaatga ctgataacag actaattaac ggaggttaag atgaaatttt
    27661 tcttagacac agcaaatgta gaggcaattc gtgcgattaa tgagcttggt gttgtggacg
    27721 gtgttaccac aaaccctagc attatctcgc gtgagggtcg tgattttgag acagttatca
    27781 aggaaatctg tgagattgtg gacggcccta tcagtgcaga ggtcaccgga ctaaccgcag
    27841 aggaaatgat tgcagaggct aggaacattg ccaagtggca tgacaatgtg gtcgtgaaaa
    27901 ttccgatgac gacagagggc ttaaaagcaa ctaatgtctt gtcacaagaa ggcatcaaaa
    27961 caaatgtgac gcttattttt acagttagtc agggactaat ggccatgaag gctggtgcga
    28021 cctatatcag tccatttatt ggtcgcttag aggatattgg agcagatcct tatcagctta
    28081 ttagtgattt gcgtgggatc attgatttgt atggcttcca agcagaaatc atcgcagcca
    28141 gcattcggac agctgcccat gttgaagctg ttgcacagct agggggacac attgcaacca
    28201 ttccagatcc attatttgcg aagatgactg agcacccatt gacaacaaat ggcttaaaga
    28261 cctttatgga ggattgggct tcctttaaaa aataggctaa gagcatagag ctctccttat
    28321 attctaatgt ggctgtagcg gttagtttgg gattagctat ttgtaggtgg caggatcagc
    28381 tggtgctttg ctgttgcgct agaattaaca ggcagctggc gcttactgta gccaaaggga
    28441 ggtaccaaag aggaatgctt gcttagctgg caacagctag gcttgctttt tcttatgagc
    28501 ataggtgctc tatctaagac agctgtcaat cacaaaaagc taggaacagc aatgcttatt
    28561 gctagataag aatttaagga ctttatagga ttttgttaaa aatcagttta cttttatgtt
    28621 acaatagaca atggaaaacg tttaattttt agttgtaata cacagagagg ttttacttat
    28681 gacatttgat gcaattgatc agctggcagt taatactgtt cgtactctat caatggacgc
    28741 tattcaagca gcaaattctg ggcatccagg tttgccgatg ggggcggcgc cgatggctta
    28801 tgtgctatgg aatcatgtta tgacagtcaa tccaaagaca agccgccgtt ggtcaaatag
    28861 agaccgcttt atcctatcag caggtcatgg tagtgccatg ctttacagcc tgttgcacct
    28921 agcaggctat gatgtgtcta ttgaggatct taagaacttc cgtcaatggg gctctaaaac
    28981 accaggtcac ccagaggtca atcatacaga tggcgttgag gcaaccacag ggcctttagg
    29041 acaaggagtt gccaatgcag ttggtatggc tatggcagag gcacacttag cagctaagtt
    29101 caatagacct ggctttgata ttgtagacca ctatacctat gctctaaatg gtgacggaga
    29161 ccttatggag ggtgtcagtc aggaggcagc cagtctggca ggtcacttga agcttggtaa
    29221 gcttgtcttg ctatatgatt caaacgatat ttcgcttgat ggcccaacct caatggcctt
    29281 cacagaagac gtcaaggggc gttttgaagc ttacggctgg cagcatatcc ttgttaaaga
    29341 cggcaacgac ctagaggcca ttgctaaagc tatcgaggaa gctaaggcag agactgaaaa
    29401 gccaaccatt attgaagtaa agacaatcat tggctttggt gctgaaaagc aaggaacttc
    29461 agctgttcat ggggctccgc ttggtgcaga aggcattgcc tttgctaaga aatcttatca
    29521 atggacccat gctgattttg aggtgccgca agaggtgact gagcgcttta gacaaggcct
    29581 tcaggcgcgt ggtgagcagg ctgagcaggc atggaatgac ctatttgcag cttatgaagc
    29641 agcataccct gagttagcag ccgaatacaa aaaagccttt gctaatgagg cggcagaggt
    29701 tgagttgcaa gctcacgagc ttggcacagc agtagccagt cgtgtttcta gccagcaggc
    29761 tatccaacaa atctctgagc aggtgccagc cttctgggga ggctcagctg acctttctgc
    29821 ctctaacaat accatggtta aggctgagac agacttccag ccgggtcatt atgctggtcg
    29881 taacatctgg tttggcgtac gcgaatttgc aatggcagca gcgatgaacg gtattgccct
    29941 tcatggtgga acacgtgttt atggcggaac cttctttgtc ttttcaaact acctattgcc
    30001 agcggttcgt atggcagcct tgcagcagct accaacggtt tatgtcatga cgcatgattc
    30061 tatcgcggtt ggtgaagatg gtccgaccca tgagccaatc gagcagctag ctagtgttcg
    30121 atcaatgcca aatctgaacg ttattcgtcc agctgacggc aatgaaacaa acgctgcttg
    30181 gaagcgtgcg atcgctgaga cagaccgtcc gacaatgctt gtcttaacac gtcaaaacct
    30241 tcctgtactt gaaggtacta aggaattggc agaagatggc cttaataagg gagcttatat
    30301 cctgtcagag gcaaagggtg accttgatgg gattatcatt gcaaccggct ctgaagtcaa
    30361 gctagcaatg gatactcaag ccgctcttgc agcagatggt atccatgtgc gtgtggtatc
    30421 aatgccatca caaaatatct ttgatgagca gccagcttcc tacaaggagg aaatcctacc
    30481 agcagcagtg acaaaacgtc tagctattga agcaggctca agctttggct gggcaaaata
    30541 cgttggcctt gcagggaaaa cactgaccat tgatacatgg ggagcttctg caccgggcaa
    30601 tcgtatcttt gaagaatatg gctttacagt agagcatgct actgaattgt acaaatcctt
    30661 atcataagtg attaagctgg agcaggcctt atctaggctt gctttcggca ttattagaca
    30721 aaaaaacgca tgatgttcaa ccctttttag ggaggacgtc atgcgttttt gtttcagatt
    30781 taatagtgct actgctcagc cttgcagatc tatcccgagt tgctagaagc tattgtcaaa
    30841 tagctggctt agcttttctt tctttttagg gttagcagac ctgcgctagc gatgacgcta
    30901 agagctgcca gactaaagaa tggatggctt gcctctcctg tagctggtag gactgctttt
    30961 ttgcttggtg ttgactgagg tgctggtgcc ttagggctag ctgactgctc tgaagccttt
    31021 ggagctttcg gtgcaggagc cttttcagga gcctgtggct tctctggcat ttttggtgat
    31081 tctggtgcct ttggaactga tggcttggta tcctttcctt ggtcaccctt tggctgttgc
    31141 tcaccatttt caccgcgttg accttgctcg cctttttcgc cacgttgacc ttggtcgcct
    31201 ttttcaccgc gttgaccttg gtcgcctttt tcgccacgtt gaccttggtc gcctttttca
    31261 ccgcgctgac cttggtcgcc tttttcgccg cgttgacctt gctcgccttt ttcaccgcgt
    31321 ggcccttgct cgcctttttc accgcgtggc ccttgctcgc ccttttcacc a
//
LOCUS       DARYLD010000020        31131 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYLD010000020 DARYLD010000000
VERSION     DARYLD010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31131
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU651_000796"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TU651_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL0896811.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TU651_000797"
     CDS             complement(1584..2021)
                     /locus_tag="TU651_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL0896812.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TU651_000798"
     CDS             complement(2008..3234)
                     /locus_tag="TU651_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0896813.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU651_000799"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TU651_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL0896814.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU651_000800"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TU651_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL0896815.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TU651_000801"
     CDS             complement(5505..6662)
                     /locus_tag="TU651_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL0896816.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU651_000802"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TU651_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL0896817.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TU651_000803"
     CDS             complement(7553..8392)
                     /locus_tag="TU651_000803"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL0896818.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TU651_000804"
     CDS             8708..10276
                     /locus_tag="TU651_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL0896819.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TU651_000805"
     CDS             10269..11009
                     /locus_tag="TU651_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0896820.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TU651_000806"
     CDS             11357..11473
                     /locus_tag="TU651_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL0896821.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TU651_000807"
     CDS             complement(11997..12887)
                     /locus_tag="TU651_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL0896822.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TU651_000808"
     CDS             complement(13150..14814)
                     /locus_tag="TU651_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL0896823.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TU651_000809"
     CDS             complement(14814..15179)
                     /locus_tag="TU651_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0896824.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TU651_000810"
     CDS             complement(15331..15519)
                     /locus_tag="TU651_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL0896825.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TU651_000811"
     CDS             complement(15979..16344)
                     /locus_tag="TU651_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896826.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TU651_000812"
     CDS             complement(16934..17815)
                     /locus_tag="TU651_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL0896827.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TU651_000813"
     tRNA            complement(18018..18103)
                     /locus_tag="TU651_000813"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TU651_000814"
     CDS             complement(18158..19084)
                     /locus_tag="TU651_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL0896828.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TU651_000815"
     CDS             complement(19444..21057)
                     /locus_tag="TU651_000815"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL0896829.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TU651_000816"
     CDS             complement(21331..21897)
                     /locus_tag="TU651_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL0896830.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TU651_000817"
     CDS             complement(22164..23447)
                     /locus_tag="TU651_000817"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL0896831.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TU651_000818"
     CDS             complement(23796..25205)
                     /locus_tag="TU651_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL0896832.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TU651_000819"
     CDS             25656..26495
                     /locus_tag="TU651_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL0896833.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TU651_000820"
     CDS             complement(26591..27151)
                     /locus_tag="TU651_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL0896834.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TU651_000821"
     CDS             complement(27164..27637)
                     /locus_tag="TU651_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0896835.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TU651_000822"
     CDS             complement(27643..28392)
                     /locus_tag="TU651_000822"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL0896836.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU651_000823"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TU651_000823"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL0896837.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TU651_000824"
     CDS             29318..30682
                     /locus_tag="TU651_000824"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL0896838.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
BASE COUNT         9263 a         7450 c         5669 g         8749 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat gctgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggtgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattggg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa g
//
LOCUS       DARYLD010000021        30870 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYLD010000021 DARYLD010000000
VERSION     DARYLD010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30870
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(229..699)
                     /locus_tag="TU651_000825"
                     /pseudo
     CDS             complement(229..699)
                     /locus_tag="TU651_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            914..1135
                     /locus_tag="TU651_000826"
     CDS             914..1135
                     /locus_tag="TU651_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL0896839.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1165..1458
                     /locus_tag="TU651_000827"
     CDS             1165..1458
                     /locus_tag="TU651_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0896840.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            2595..4427
                     /gene="lepA"
                     /locus_tag="TU651_000828"
     CDS             2595..4427
                     /gene="lepA"
                     /locus_tag="TU651_000828"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL0896841.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            4969..5406
                     /gene="msrB"
                     /locus_tag="TU651_000829"
     CDS             4969..5406
                     /gene="msrB"
                     /locus_tag="TU651_000829"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL0896842.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            5694..6713
                     /locus_tag="TU651_000830"
     CDS             5694..6713
                     /locus_tag="TU651_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL0896843.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            7057..7482
                     /locus_tag="TU651_000831"
     CDS             7057..7482
                     /locus_tag="TU651_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL0896844.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            7497..7988
                     /locus_tag="TU651_000832"
     CDS             7497..7988
                     /locus_tag="TU651_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0896845.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            8006..8815
                     /locus_tag="TU651_000833"
     CDS             8006..8815
                     /locus_tag="TU651_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0896846.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            8812..9639
                     /locus_tag="TU651_000834"
     CDS             8812..9639
                     /locus_tag="TU651_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0896847.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGVVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            9829..11463
                     /locus_tag="TU651_000835"
     CDS             9829..11463
                     /locus_tag="TU651_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0896848.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            11467..12252
                     /locus_tag="TU651_000836"
     CDS             11467..12252
                     /locus_tag="TU651_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0896849.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            12276..13286
                     /locus_tag="TU651_000837"
     CDS             12276..13286
                     /locus_tag="TU651_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL0896850.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            13539..15323
                     /gene="uvrC"
                     /locus_tag="TU651_000838"
     CDS             13539..15323
                     /gene="uvrC"
                     /locus_tag="TU651_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL0896851.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            15451..16053
                     /locus_tag="TU651_000839"
     CDS             15451..16053
                     /locus_tag="TU651_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL0896852.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            16134..17543
                     /gene="pepV"
                     /locus_tag="TU651_000840"
     CDS             16134..17543
                     /gene="pepV"
                     /locus_tag="TU651_000840"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL0896853.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(17810..19186)
                     /gene="mnmE"
                     /locus_tag="TU651_000841"
     CDS             complement(17810..19186)
                     /gene="mnmE"
                     /locus_tag="TU651_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL0896854.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            19458..19679
                     /locus_tag="TU651_000842"
                     /pseudo
     CDS             19458..19679
                     /locus_tag="TU651_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            19802..20116
                     /locus_tag="TU651_000843"
     CDS             19802..20116
                     /locus_tag="TU651_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0896855.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            20121..20453
                     /locus_tag="TU651_000844"
     CDS             20121..20453
                     /locus_tag="TU651_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL0896856.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            20455..22053
                     /locus_tag="TU651_000845"
     CDS             20455..22053
                     /locus_tag="TU651_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896857.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            22047..22733
                     /locus_tag="TU651_000846"
     CDS             22047..22733
                     /locus_tag="TU651_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896858.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            22755..23441
                     /locus_tag="TU651_000847"
     CDS             22755..23441
                     /locus_tag="TU651_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896859.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            23463..24140
                     /locus_tag="TU651_000848"
     CDS             23463..24140
                     /locus_tag="TU651_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896860.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            24147..24461
                     /locus_tag="TU651_000849"
     CDS             24147..24461
                     /locus_tag="TU651_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0896861.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            24909..25592
                     /gene="rpiA"
                     /locus_tag="TU651_000850"
     CDS             24909..25592
                     /gene="rpiA"
                     /locus_tag="TU651_000850"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL0896862.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            25670..26881
                     /locus_tag="TU651_000851"
     CDS             25670..26881
                     /locus_tag="TU651_000851"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL0896863.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKTLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            27094..27903
                     /locus_tag="TU651_000852"
     CDS             27094..27903
                     /locus_tag="TU651_000852"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL0896864.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            27994..28779
                     /locus_tag="TU651_000853"
     CDS             27994..28779
                     /locus_tag="TU651_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL0896865.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(28912..29820)
                     /locus_tag="TU651_000854"
     CDS             complement(28912..29820)
                     /locus_tag="TU651_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0896866.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            30160..30609
                     /locus_tag="TU651_000855"
     CDS             30160..30609
                     /locus_tag="TU651_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896867.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
BASE COUNT         8883 a         5589 c         7041 g         9357 t
ORIGIN      
        1 ggttgagtaa ggtgtggact aaaacaagtg ataaagtcgg gaatgacttt tgtaggcata
       61 atttcacctc gtgacgatac cgttacttct ttttgaccaa gaaaagaaaa tgaaagtaaa
      121 aatatgacga ataatgttaa tggtataata agaattatcg caaaattatg atagcgtcgc
      181 tgataaaatt cagcacttct aaacagattt ggattcatga atatctcctt acttactaaa
      241 taaatgatga tagaagcctt gatgcgtcat taattcgtta tgcgaaccta tctcgattat
      301 ttttccttta tcaagtacaa caatttggct agtacgttca gcagtactaa gacgatgggc
      361 aacgaaaata atcgttttct cggtcattga cattaggtta tcaatcactt ttttctccgt
      421 taagacatct agtccgcttg tcgcctcatc gagaattaga ataggagact tggttaataa
      481 tgctctagct aatgcaattc tctgtttttg tccaccagaa aatcctgccc catcagatag
      541 ttctgtctga tagcccatag gcatttgttc aatatcttct ctaatttctg ccatatcaca
      601 ggcattgata atatcctctt gagtaatcgc ttggtttgca ccgagagtaa gattttctaa
      661 aattgatcca ctaaaaatat aagcttgttg aggcagatat tggttatcga aacgtcctaa
      721 atggtaatct gacaaatcta tcaaattatc tcaaacggtt gaatttaagt cttaagcggt
      781 aaatttttcc catttaggac gtttcgatga ctgtttagga aatggagaac aaattttaac
      841 cgaaagtgtt atactaagtc tgtcaagctt gcaaccggac aaaataaaaa cacatataaa
      901 ggaggtattc gtcatggata caaaatttac agcgttgact gaagagcaat tgaaatcagt
      961 tgagggtgga aaaaatggag ttgtaaaatt acctggaggg accggtgtat attgttggaa
     1021 tacaggaaaa aatagtgcaa aatgtggtat ggactggagt gtggcaggac catatgttgg
     1081 taagataatt gtcaatggtt gggttaacca tggaccttgg gcaagtcgtc cataatttta
     1141 atttatatag agaggtgtga aatcatgaat gaaagagatt tagtacagct gatagaacag
     1201 actctaaaag atgaagaggt gcaaaataat gtcacttata ggaatctttt ggaagaaagt
     1261 ctccagcaat tatcactcaa aaagcctgtg tatttagtta gtaccaggtt agcaggacat
     1321 atttcaacct atctaatgac aaatcattat gaggcaccaa aagcgattat agttcttgct
     1381 caatctatcg catcaacccc agctaaacat agaggtttaa tttctatacc attctggtta
     1441 agtaatatat ttcgttaaaa aatattttca gatcaggatt tagaaggagt tgtagattgg
     1501 caatgcactc ataaaataag acacattttt tggagttttt tgcttgaact cctaactttt
     1561 acattagtct ataaacagtc aaaggaagtt ctttcaatct ctcaaattgc aaaacaattt
     1621 tggctatatt ttaaaagtac aattttgatt ccaattttag ttacaatcat tcttataaag
     1681 gagattttgt caagtacatt acaaataatg atttattttt accttaatgt tgttgtcatg
     1741 tgctacgcta ttggaatgat cttatcgtta ggttatgtga tttcacccaa gcactctata
     1801 ttcaataaaa ttaaaaatat aaaattaaat aatagagtat cccaagagat tgccgaatcc
     1861 caatttacca gtcttttaga gcgaagagcg acttgaagaa actgataaat ttatttggtt
     1921 ttctgctaaa aatcctgcca aaaaatcttt ggcaggattt ttattttact aagagatatt
     1981 taggagtggc tttgtcattt aatgcagatt atgatatagc aggagacata ttgttgaagc
     2041 tgtctatgtc acttttggtg gcaggtaggt cttattggaa ttggtgactt atgacattta
     2101 tcggtggctg taagcgtttg actttttcac gtttcatagt ggtccgctct ggaatgagtg
     2161 ggtatttttt cagaatatga tcaaagatag atgacatgtt ttacagcagg ctatagctgg
     2221 tatgatttgt ttaaaaaatc aaggccaatg ataagtgctg ggtgacataa gtcttatggc
     2281 tttacttctt gttagcttgt gtcagcaggt gctgagtcaa tcgttgtagg aattatcgta
     2341 aacctaacag tagctgctgt tctatttgtt tattttctgg tttctattca aatttctaaa
     2401 atgctagggt aacaaatatg aaacaagcaa gtggcgtact gcgaacagct tgataactta
     2461 ttgcctgctt aaagagggtg ctgttatgct tggttttatt aggcttatgg catgggatta
     2521 aaaggttgct gtagcgccat tgtcattatt ttggtacaat aataggtaaa agactaaatg
     2581 tataggaaaa tagaatgaac agtcaagaat taaaaaaacg tcaggagaac attcgtaatt
     2641 tctctattat tgcccacatt gatcatggta agtcgactct tgctgaccgg attttggaaa
     2701 agacagaaac ggtttcaagt cgtgaaatgc aggcacagct ccttgattca atggacttgg
     2761 agcgggagcg tgggattacc atcaagctaa atgcgattga gctgaattat aaggctaaga
     2821 atggtcaaga ttatattttt cacttgattg atacaccagg gcatgtggac tttacctatg
     2881 aggtgtcccg gtcactagct gcctgtgagg gtgctgtttt agtggtggat gctgctcagg
     2941 ggattgaggc acagacccta gcaaatgtct atctggcgct tgataatgat ttggaaattc
     3001 ttccagtgat caacaagatc gatttgccag cagctgatcc tgagcgggtt cgtcaggaaa
     3061 ttgaggacgt gattggtcta gatgcttcgg aggctgtact tgcctctgca aagtctggga
     3121 ttggtattga agatatttta gagcaaattg ttgaaaaggt tcccgcaccg tctggtgatg
     3181 ttgatcaacc gctgcaggcc ttgatttttg attcggttta tgatgcttat cgtggggtta
     3241 tcctgcaggt gcgtgttgtc aatggtatgg tcaagccagg tgatacgatc caaatgatgt
     3301 caaatggaaa aacctttgat gtgactgagg tggggatttt tacccctaag gctattggta
     3361 gggattttct tgctactggt gatgttggct atattgcggc ctcaatcaag acagttgctg
     3421 atacgcgtgt cggtgatacg gtcactctgg ctacaaatcc tgcagcagag cccttgcatg
     3481 gctacaagca gatgaatcca atggtgtttg cagggattta cccgattgag tctaacaaat
     3541 acaatgatct tcgtgaggcc ttagaaaagc ttcagcttaa tgacgctagc ttacagtttg
     3601 agcctgaaac ctcgcaagca ttgggctttg gttttcgttg tggctttctt gggctgttgc
     3661 acatggatgt cattcaagag cgtttggagc gtgaattcaa cattgatttg atcatgacag
     3721 ctccgtctgt tgtctatcat gttaatataa ctgatggtga catgcttgag gtctctaacc
     3781 cgtcagaatt tcctgatcca actaaggtag atagtattga ggagccttat gtcaaagccc
     3841 agatcatggt gccgcaggag tttgttggtg ctgttatgga gttggcccag cgtaagcgtg
     3901 gagattttgt gacgatggat tatattgatg acaatcgtgt caatgtgatt taccatattc
     3961 ccttagctga aattgtgttt gacttctttg ataagctgaa atcatcaacg cgaggctatg
     4021 ctagctttga ctatgaaatt gctgaatacc gtcgctcgca gctggtgaaa atggatattt
     4081 tgttgaatgg tgataaggtt gacgctctta gctttattgt tcatagagca tttgcctatg
     4141 agcgcggtaa gctgattgtt gagaaattaa agaaaattat tcctcgtcag caatttgagg
     4201 tgccgattca agcggctatt ggtcaaaaga ttgtggctcg ctctgatatc aaggccttac
     4261 gcaaaaacgt tcttgctaaa tgctatggtg gcgatgtttc ccgtaagcgt aagttgcttg
     4321 aaaagcaaaa ggctggtaag aagcgtatga aggctattgg ctctgttgag gtgccgcagg
     4381 aggccttctt gagcgtccta tcaatggacg atgagagtaa gaaatagtga catgttaagt
     4441 aaggagctgg atcatgcgat ctggctctta tgcttgatgt ctcgataggc tagaaaatag
     4501 ggcttgtgtc atgataggct tgtatgtttg agatggtttg gaacataatg actctatcat
     4561 atctgtagtg gattgacaaa gagccgtaaa ccattgatat ttggatagtt aatttcgagt
     4621 tattctgtag tactctctta aggtctttca tatgagcttt tctaatgttg gtttggttgc
     4681 ttttcatgat aagtcatatg ggattttttt ggtatactga aaaaagccta tagcctctac
     4741 agtggcgtct ccctctacag agatgataga gccagagtga ttgttacgat ctggagatgt
     4801 ggcgctaggc attaatgcag gaggacttaa ccagattgct gttaggcttg aaatcttaag
     4861 ctatattgat tgtcagcttg atttagagaa gtctaagttt atggctcaca aatgctcggt
     4921 ctttttgtta caatagagtt aatcagttat ttttataagg agacagctat ggaatctaag
     4981 gaagagcttc gccagcgtat tggagatttg gcttttgagg tgactcagca tgcagcgacc
     5041 gaaagagcct ttacaggtca gtatgatgat ttttttgaga aggggattta tgttgatgtg
     5101 gtgagcggag aggtgctctt ttcctctttg gataaattca attctggctg cggctggcct
     5161 gcattttcta agccgattca gcatcgtatg gtaaccaatc accatgattc atcacatggc
     5221 atgcggcgtg ttgaggttaa aagccgcgag gctggctccc atttggggca tgtttttaat
     5281 gatggcccta aggaggcagg aggcttacgc tattgcatta actccgccgc gctgaaattt
     5341 atcccctatg atcaaatgga gcaagagggc tacgccgaat ggttagggat ttttgataag
     5401 agctaggaat tgctagcggc caatgaaaag gtagagctct tagccaatgc tagtggctaa
     5461 atcaaagaaa taaaaaggtg gctaaagtac atagaaaaaa gaggtaagca gattggcagg
     5521 tggtcaatct gctttttgtg aggagacttt cagcctgctt tgcgctaaaa agtatgaaac
     5581 caataaacca cctactatgc gggtgtgtgt cggtggttag cttaagtttt ttcagttcgg
     5641 ttttacaagc ttctctaaaa ggactataat agctaatgga aaaggagatt catatgctaa
     5701 catctttaga aaaattaccg ggcgttttac tgtgcttgct gttagcactg cctgcctggt
     5761 atttgggaag cttatttcct attattggag cgccagtttt tgctatttta ttgggaatgc
     5821 tattggcgct tgtctatcag aagcgtgact acactaaatc tggaatcgca ttgacgtcca
     5881 aatatatttt gcagctggct gtggttttct tgggctttgg cttaaacgtg acacaggttt
     5941 tagtggttgg cttgcaatcc ctgccgatta ttgtagtaac gattgtgact gccttgggca
     6001 taagctattt gttcaaaaga tggttaaggc taccagccaa gacagctatc ttagttggtg
     6061 tgggctcgtc tatttgtggt ggctctgcta ttgcagccac agctcctgtc attgatgcgc
     6121 aggacgatga cattgccaag gccatttcgg ttattttttt gtttaatatc ttggcggcct
     6181 tgctatttcc agctttgggt cagatgcttg gcttatcaaa tcatggcttt gctatttttg
     6241 ctggaacagc agtcaatgat acctcatctg taacagctac agcgacagcc tgggacgcta
     6301 ttcaccagtc taatacgcta gatggggcaa ccattgtcaa attaaccaga acgctggcta
     6361 ttattcccat aacacttggc ttatctattt accaaaccaa gagcaggcag gcacatacga
     6421 cagagggttc ctttagcctc agaaaggctt ttccgacctt tattgtcttt ttcttgctag
     6481 cttccttgat aaccaccttt gctgctagct taggtctgcc aatggcaatc tttcatcagc
     6541 ttaagctact ctcaaaattc tttatcgtta tggccatggc agcgatcgga cttaatacca
     6601 atctagtgac cttagtcaaa actggtggta aggccatttt gctgggtggg atttgctggc
     6661 tagcgatcac atcagttagc ttagcaatgc aggcagcttt ggggagctgg taactgatga
     6721 gaatagctgg tgatacgctg ctttatagga aaagcaaagc ccttgctgct cctaaaaaag
     6781 cttgttagag cagctcactt agctgttaag tgtggcttgg tggggtgtaa gtaggctcta
     6841 tcagttagaa aagccatcag aacaaacgct atcattaagc tgaagccggg gaaactcggc
     6901 ttttacgtta tgcagaattg tctacatatt gaataggatt atccatttta aaaacgtttt
     6961 catttgatag aatacaatta tagcttggtt attagggtaa acgagattga acttcttatc
     7021 tggtttagct taagtaaaaa agcagttgga ggaagcatga aacgtaaatt tttaattggt
     7081 agtcatggga gaatggccag tggattgaaa agctctattg acattttggc tggtagaggt
     7141 caggaattac aagtcattga cgcttatatt gatgatagtg attatactga gcaggtattg
     7201 acctttatcg aagatgtagc agctgacgag caggcactga tttttacaga tttattaggt
     7261 ggcagtgtta atcaaaaaat agtaactgcc ctaatggaca gtggcaagga aaatatcttt
     7321 ttgatttcaa atagtaatct tgcagccttg ctatcgttga tgtttttaaa gccagaagaa
     7381 gagctgacaa aagacgagat tgtagcaacg attaacgatt ctcaggtgca gctggtggat
     7441 ctagctccag cgacagccgc agaagatgac ttttttaatt gaggaggaaa aatgaaatga
     7501 ttacacaaat tcgtgttgac gacagattga ttcatggaca ggttgctgtt gtttggacca
     7561 aggagcttaa tgcccctttg cttgtggtgg ctaacgatga ggctgctaaa aatgagatta
     7621 cacaaatgac tctaaaaatg gcagttccta atggcatgaa attattgatt cgctctgttg
     7681 aggactctat caaggttttc aatgatccac gcgcagtgga taagcgtatt tttgtcattg
     7741 tcagctcgat taaggatgct tgccagattg caaagcaggt gaaggactta gaggctgtta
     7801 acgttgcaaa tgtagggcgc tttgacaagt cagacccagc aactaaggtc aaattggctt
     7861 caagcctatt gttaaatccg gctgaattag aagcagcaaa agagctggtt agcctgccta
     7921 acctagatgt tttcaatcag gtactgccat ctaatagcaa ggttagcctg agccagctca
     7981 tcaaataaag aaaggtgtaa tgactatgtt agtaccagca acaatggcag ccttagctgt
     8041 attgatttgt ttcgggggaa attatttaac tggccaaagc atgatggaaa gaccgcttgt
     8101 ggttggtttg gtgacaggat tgctcttagg agatatgaag gtcggtatct tgatgggagc
     8161 gtcactagag gcacttttcc taggaaatgt taacattggt ggtgtcattg cagcagagcc
     8221 tgtaacagca acagctatgg caacgacctt taccatcatt tcacatattg atcaaaaagc
     8281 agctatgacg ctagctgttc cgattggcat gctagcagcc tttgtggtca tgtttttgaa
     8341 aaatgttttt atgaatatct ttgcgccaat ggttgataag gcagcagcgg caaaccatca
     8401 gggcaagctt gtcatgctgc actatggcac atggattgtc tattatttga ttattgcctc
     8461 tatttccttt atcggtatcc tagttggaag cggacctgtt aacgcctttg ttgagcatat
     8521 tccacaaaat ctgatgaatg ggctaagtgc agctggtggt cttcttccag cagtcggatt
     8581 tgccatgctg atgaagctct tatggacaaa taagctagca gttttcttcc tattaggctt
     8641 tgtgttgaca gcttatttga agctaccagc agtagctgtg gctgcacttg gtgcagttat
     8701 ctgtgtgatc agctcgcagc gtgatttaga gttagatgct attactaagg gagctatcag
     8761 taaccaaagc agctttgact ctaaagaatc agaagaggag gacttctttg catgagatct
     8821 caagacaatt taactaaaga agaaagaaaa atgctacgct ctgttttctg gcgttcatgg
     8881 accatgaatg ctagtcgtac aggagctacg caataccacg ctgttggggt tatctatacc
     8941 ttgttgcctg ttatcaatct cttttataag acagataagg ataaggcaga cgctcttgtt
     9001 cgtcacacca cttggtttaa tgcgaccatg catattaata actttatcat gggcttggtt
     9061 gcctcaatgg aaaagaaaaa cagtgaggat ccaacctttg acgctagtgc tattacagcg
     9121 gtcaaggctt ccttgatggg acctatttct ggtgttggag attccttttt ctggggtatt
     9181 ttgagggtca ttgcagctgg tattgggatt tcacttgcta gcacaggctc agcgatggga
     9241 gcagtagtct ttttacttct ctataatatt cctgctttta tcattcatta ttatagcctt
     9301 tatggtggct attctgttgg tgctggcttt attaaaaagc tttatgagtc tggtggtatt
     9361 aagattgtga ccaagacctc aagcatgctt gggtcaatga tggttggctc catgacagct
     9421 tcaaatgtga agtttaagac cattttaaca gttgctgcaa agggagccaa ggaagcagcc
     9481 tctatccaaa attatttgga tcagctcttt attggagttg tccctctttt agtaaccatg
     9541 accgcctttt ggcttttgcg taagaaggtg aacattaact ggattatgtt tggcattatg
     9601 ctattgggta ttgttcttgg tcttttaggt atttgctaat aatctcctag catcaaggat
     9661 aggtaaggca gggacttctt gctttgctta tccttttttg tagtgagggc tgctgaaata
     9721 gccacctgct tgcttaaatg gcttatggat ttgttagata gattaagatt ttcttagctt
     9781 tgagaaatga tttggtataa tagaaggaaa taagggaaaa ggctgcctat ggaagaaaga
     9841 tttaaaaagc gattgcagga tgatatttca catcattttt cacaccaatc attgattttg
     9901 tccattttac tgattggact ctttctcatt ttttcattgg cacctcagca aattgggctg
     9961 tatcaagatt tgaaggctgt tgaacatagc tatcaccagc tgattcggca aaataaggcg
    10021 cttttaacgg agctcaatca gcatattctg accaaatttg tgaatcatca gctgagctct
    10081 tctgacctta gcaaacaata ttatcaccta agaaaccgct cacaaagcca atcagagctg
    10141 ctggtttttg atgctaacag tcacatgctg tttgctagta atcagcatct gggaaatttt
    10201 tttcgcaatg ctgtctatat gacagaagtc ttaaaaaaag caaggcaaag gagtagcttc
    10261 ttgaggatca gtatggataa tgaggagggg cattatttac tgctgataaa gcctattaag
    10321 atagatcatc aggttaaggg ctattcgctt cttgtgatga atggtaagga ttttcttcag
    10381 ctatcacatc agattgcttc agattttgtg attgcagatc agtttgacaa tagctttgcc
    10441 tttaccaatc ggacctttat gacctcaagt ctgaataagc ttgacagtca ttttcttaag
    10501 ggctatttta tctttcacga gcatcgtgcc tttatcctaa gaaaggtcgc tcttagtcct
    10561 tctatcactc tttacagcta ccgccctttg attccagttt ctattgcact cttgttttca
    10621 ttgatgtcct ctgtcatgat ttatgctatt ttgtattgga agtctaaggc tctggcgacg
    10681 cagattgctt ctagcaattc agcagcgatc aatcagatga ttcttgatat gcaggccatc
    10741 tcaaggcagg aaaaaaatgc cattgacctg caaagtcaag atgaatttca atacctgtcg
    10801 gttcagatca atcagatgat tagccgattg caggcacttc atcagaagac cctagcctta
    10861 gaaaagcaaa atgtgagttt tgaaaaacgc atgctggaag cccaatttaa ccctcatttt
    10921 ctctataata cacttgaaac aattttgatt acaagtcatt atgacagtga cctcacagaa
    10981 aaaattgtcc ttcagctaac caggctgctt cgctatagct tagacgaatc acaggaggct
    11041 gtgtgtctgg gagaggattt ggctgtctta gaatcctatc tgttgattag ccagattagg
    11101 tttgaagagc tgcgctacac gatagctgtt gaaccagccc tagagaccct aagggttccc
    11161 aaattatttt tattgccatt gattgaaaat gcgatcaaat atggtctgcg ctatcgccat
    11221 gaccttgtga ttgagatcag cgtgagacag cttgctgatg gaatttactt tactgtagca
    11281 gataacggtc ctggaattag tcaaaaaagg caggccgata ttaaagagct cttgcattca
    11341 gaggattcac atcatggctt ggtcaattct tatcgtcgac tcaagcatca atttataaaa
    11401 gttgaattga tcttttgtca aagagatgag cgctttttac taacctatat ggttaaggag
    11461 taacagatgt ataagctact aattgttgaa gatgagcata ttattcgcaa atggcttcgt
    11521 tatgcgattg attatcatgc gctcaatatc cttgttatcg gagaagctaa ggacggtcag
    11581 cagggggcta agctgattgc agaggctaag ccagatattg ttttgacaga cattaacatg
    11641 ccgattatga ctgcctttga gatgtttgag gccacaaaag agcagtccta tgctaaaatc
    11701 attttgtctg gctatgctga tttcgctaat gcaaagtctg ctatccatta tggtgtgctt
    11761 gagtttttga ccaagccctt ggaaaggcag gccttacatg attgcttgct aactattatc
    11821 caaaagctgc aacagcagtc tcaagagcag gagctaagcc agcagcagga ttacctcaaa
    11881 ctgccacagc ctaatgacca attgcctgat gttgtccaag aaatgctcag ctggatccat
    11941 gagcattacc aggataaaat catgattggt cagttggctc acgatctggg ctatagcgaa
    12001 agtcacctct atcatttagc taaaaaatac ctgaaaatga cttttagtga ctatatcaac
    12061 caataccgcc tgaatcgagc aattcaattg ctgattgctg agccggatgt gatggtttat
    12121 cagcttgcag aggctgttgg catttatgac taccgctatt ttgatcgtgt gttcaaaaaa
    12181 tatttaggac aaacggtcaa ggatttcaga gaaacggtat tacaccagag atcagatagg
    12241 agttcattgt gacaagaaaa aagctgctat tagcaatggc aatagtgata ctaggtgtga
    12301 ttggctctgg cttgtatgct atctggaggc atcaagcagg accagctccc agcaaaccaa
    12361 gagaattggt tgttttgaca cccaacagtc aaaatatcct aacaggtacg atcccagcct
    12421 ttgaagaaaa atacggcatt aaaatccgtc tgattcaagg aggcacaggc cagctcattg
    12481 atcgcttgca aaaggacaag gaccagctcc atgcagacat cttttttggg gggaattaca
    12541 cacaatttga gagtcataag gagctatttg agccttacct ttcaaagcat attggctttg
    12601 tattgcctga ttacctgctg caaagcgagg tcgcaacccc ctatacgctt aatggaagtg
    12661 ttctcattgt gaataatgaa ttggcaaagg acatggttat taccagctat gaggatttgc
    12721 taaagccaga gctaaaggga aagattgctt ttgcagaccc caacacctcc tctagtgcct
    12781 tttctcagct gaccaatatt ctcttagcca aggggggcta cactaacccc aaggcttgga
    12841 gctatatcaa gcagttgatt catagcatga attcaatcaa atctgctagc tcatcagatg
    12901 tttatcagtc agtagcagaa ggaaagatga ccgtcggtct tacctatgag gacccctgtg
    12961 ttaacctttt aaagagtggt gccaacgttt ctattgtgta tccaaaggag ggaacggttt
    13021 ttttaccctc agcagttgcc attgttaagc aatctaaggc caaggctgat gccaaattgt
    13081 ttattaatta tatgttgtct ttagatgtgc agcgggcctt tggtcaatca accagtaata
    13141 ggccaattcg aaaggacgct aaggccagtc aagacatgaa gcctttagat gacattatca
    13201 cgctaaagga agactatgat tatatcacaa gacataaaaa ggatatttta gaacgataca
    13261 atcaattgag aaagaccact gactaaatgg ctttgttata tgaaacagtt catgctgtgc
    13321 tgcacctgaa tcgttagctg ctttgtctag ctttttgagg tcaatctctg cttgggctgt
    13381 tttttatgtt accataaccc actgcatttg tttagaaagt caagcgagat cttaatagcc
    13441 agttataata ggtctttgag agggagtctg agcttgcttg aggtggcaag aagatctgtt
    13501 ttgacgtcaa atggctgaat ttttggtaaa atgatagcat gaatgaactg ataaaacaca
    13561 agctagagct tttgccagat agtcctggct gttatttgca taaggataag gctggcacta
    13621 ttatttatgt tggcaaggcc aaaaatctga gaaatcgcgt acgctcttat tttcgaggaa
    13681 gccatgatac caagacagag ctgttagttt ctgaaatagc tgattttgag tttattgtca
    13741 caggatcaaa tacagaagca ctcttattgg aaatcaattt gattcaagag aacatgccca
    13801 agtacaatat caagctaaag gacgacaagt cttatccctt tatcaagatc actaacgagc
    13861 catttccaag actattaatc acacgtcaga ttaaaaaaaa tgacggcctg tattttggtc
    13921 cctacccaga tgcttacact gccactgagg ttaaaaagct gctagaccgt atttttccct
    13981 ttaaaaaatg caaaaaccct gttaacaagg tctgctttta ctatcattta gggcaatgtc
    14041 aggctcacac gatttgccat acagacaagg cttattggga cagcttggtt gctgatgtca
    14101 agcagttttt aaacggtaag gacgacaaga tcattgatga tttgcgctcc aagatgcttg
    14161 aagcttcgca caatcaagaa tttgaacggg cagctgaata tcgtgatttg atttcaggta
    14221 ttgccaccat gcgaaccaag caaagggtga tgagtaagga cttgcaggat agggatattt
    14281 ttggctattt tgttgataag ggctggatgt gtgtgcaggt cttttttgtc cgtcagggta
    14341 agctcattca gcgagatgtg aatatgtttc cttattacaa cgaagctgaa gaggattttt
    14401 tgacctatgt cgggcaattt tatagcgacc aacggcattt gatccctaag gaggtcttta
    14461 ttccagagac gattgatgag accttggttg cagccattgt tccagcaagg attgtcaagc
    14521 cgcagcgagg ggaaaaaaag cagctggtcg ccttagcaac taagaatgct cgggttagcc
    14581 ttcagcaaaa atttgatttg ctggaaaagg atttaagaaa aacaagtggt gctattgagc
    14641 atcttggtca gctgttaggc attgaaaagc ctgttcgtat tgaggccttt gacaattcaa
    14701 acattcaggg cacaagtccg gtagctgcga tggtggtttt tgtcgatggg aagcccagca
    14761 agaaggacta tcgcaaattt aaaatcaaaa cagtgattgg tccagatgat tatgcgagca
    14821 tgagagaggt gatttatcgt cgttatagcc gcgtgaagca tgaagggcta caggcacctg
    14881 atttgattat tgttgatggt gggcagggtc aggtcaaggc tgctcgtgat gtgattgagc
    14941 accagctagg ccttagcatt ccagtagctg gtctgcaaaa aaatgacaag caccagaccc
    15001 atgaattgct ttttggtaac cccttggcag tggttgagct gccgagaaat tcagaagagt
    15061 tttttctgct gcatcgtata caagatgagg ttcatcgctt tgccattacc tttcacaggc
    15121 aggtcaggag taaaaatgcc ttttcatcaa agctagatca cattgcaggc ttagggccaa
    15181 aacgcaaaca gctactactc aagcgattta aaagcatgac tgctcttgaa caggctagtc
    15241 ttgaagaaat tcagcagcta gggattccaa aaacagtcgc tgaggcactg tttgatcacc
    15301 ttacctcaaa aagtgaggtc tgaattggcc ttgtcaggag ctcaagcagt ctgaattttc
    15361 ttgacaaaag tgaaaaaata gctgaaacca gtttcaaaaa atgatagaat gatactacaa
    15421 cataaaagaa ttagatagga agcatttgca gtgaaatttc tcgaattaaa caaaaaacgc
    15481 catgctatta aacggtttaa cgataagccc gttgattata atgacttgcg aacagctatt
    15541 gaggttgcca ctctggcacc aagtgctaac aatattcagc cttggaaatt tgtcattgtt
    15601 gaggaaaaaa aggcagagct ggcaaaggat ctgccgttgg ctaataagac tcaggtagag
    15661 caggctcagt atgttattgc cctgttttct gataccgacc tcattcagcg ctctcgtaag
    15721 attgcccgca ttggggtcaa gtccttgcct gataacttga ttggttatta catggagacc
    15781 ctgccgccac gttttgctac ctttactgag acccaaaaag gcgaatatct ggccattaat
    15841 gctggcttgg tggcgatgaa tttggtcctt gccttaacgg atcagaaaat ggcctcaaat
    15901 attattttag gctttaataa aaagctaact aatgagattt tagatattga tccacgcttt
    15961 cgtcctgaat tattgataac tgtggggtat agcgatgaca agccagagcc tagctatcgc
    16021 ctaccagtag acgaaatcat tgaaagacgc taagatacac aactactcgt ccagctagcc
    16081 tataagtttt tggatttagg aggatagcga ggcaacacat aaaggagaaa aagatgacaa
    16141 caattgattt taaagcagag gttgataagc gcaaggaagc tatgctagag gatctatcaa
    16201 acctattaag cattaattcc gagcgagacg atgctaaggc agatgccaag cacccatttg
    16261 gtcctggtcc ggttaaggcc ttggagttct ttcttgccat ggcagagcgt gatggttacc
    16321 aaacgcgtaa tattgataac tatgctggtg attttgaatt tggtcaggga gatgaggttt
    16381 tagggatttt tgcccattta gacgtggtac ctgctggtag tggctgggag acagaccctt
    16441 ataagccggt gattaaggat aatcgtatct atgcgcgtgg ttcatctgat gataaggggc
    16501 caaccatggc ttgctattat gccctgaaaa tcatcaagga attaggcttg ccagtttcta
    16561 aaagggttcg cttcattgtt gggactgatg aggagtcagg ctggggtgat atggactatt
    16621 attttgctca caatggcttg aagaaccctg attttggttt ttcaccagat gctgaatttc
    16681 ccattatcaa tggtgagaaa ggaaacatta cagaatacct tcattttgtt ggtcaaaatg
    16741 ctggagcttt tgtccttcat cgcttccaag gcggtttacg tgaaaatatg gttcctgaat
    16801 cagcgacagc tctgatcagc tcaccgcatg agcttaatgt tatcgaagct tctttggagc
    16861 aattcttatc tgagcacgca gtgacaggat ctgtcaaaga ggctgatggg ctattggaag
    16921 tgaccattat tgggaaatct gctcatggct ctacaccaga ggctggtgtt aacggtgcaa
    16981 ccctgctggc taaattctta aatcaattta gctttgatgg cgcagccaag gcttatttgc
    17041 atattgcagg tgaggtgctt catgaggatt tcacagcaga aaagcttggc ttggcttata
    17101 cagatgacaa aatgggtgcc cttagcatga atgcaggtgt ctttagcttt gctaaggatt
    17161 cagatgacaa taccattgcc ttgaatttcc gttatccaaa gggaaccaat gcagcagtgc
    17221 taaaggcagg gcttgagcaa ttaccaggct tgactaaggt taccttatct gagcatgaac
    17281 acacccctca ctatgtgcca atggacgatg agctggtctc aaccctccta tccgtctatg
    17341 aaaagcaaac aggactcaag ggctacgagc aggttatcgg tggtggcacc tttggacgct
    17401 tgcttgagcg tggtgttgcc tttggtgcga tgttcccagg tgatgaaaac acaatgcatc
    17461 aggccaatga atacatgcca ttagacaata tttaccgatc agctgccatt tacgccgaag
    17521 ctatttatga attgatcaaa taagagattg aacaagctct ctgtctaaga tgagccttgc
    17581 taatattaac gaataaaagc cttatgaagt tagtcgttta atgagacttc ataaggcttt
    17641 ttgtttggcg tcaagccatt atttacaaag agaaatgcca cagtggatca tcttttgaaa
    17701 agtccttgta aaaacagacg taaaactagt tttagaggag acattgatag gcagtcatgc
    17761 ttatcaagag atcttgtcta gcagttatgg caaaaagatc agtgaactat tattttccaa
    17821 ggcagaactg actgaacaat tgagtaatta attcatcagg tgcggcatcg cctgtgattt
    17881 ctcctaggat ttcccaagct ctggtcaaat caatctgtaa gagatcaacc ggcattccta
    17941 aagcaagtcc ttcattgaca gcctctaagc tttgtactgc ctgctcaatc aaggaaatat
    18001 gacgagcatt ggataggtaa gtcgcatctt gctctattag cccagtatga tcaaagaaaa
    18061 tctgattgat ccggtcttcg atcaggtcaa tgttttggtt ttgcaaaact gatattggga
    18121 tcgcctcttc tggaagctgg tctttttcaa tgacctgctc cagatcggtt ttattgagga
    18181 gaataatgcg attgctatcc tgactaaggg ctagcagagc cttgtcctgt tcggtcagct
    18241 tttccgaagc attgagaact aaaaggacca gatcagcctc ctgtagggct tttttagacc
    18301 gctcaacacc aatttgctct actaaatcat ctgtttctct aattccagca gtatcaacta
    18361 gctttagagg aattcccttg atattgacat attcttcaat gacatcacga gttgttcctg
    18421 caatatcagt gacaatggcc ttatcctcac gtaacaaggt attgagcaga ctagactttc
    18481 ctacattcgg tcggccgata atagctgttg acaagccctc acgtaggatc ttcccgcgct
    18541 tggcagtacg taggagctgc tctaaaagtg tttgaaattc tcgcgttttg tcacgcaaaa
    18601 gagcagtggt catttcttcg acatcatcat attcggggta gtcgatatta acctcaacct
    18661 gggctaaggt atttaggatt tcttgacgtg tgtcgctgat gagctgtgat agggagccgt
    18721 ctagctgctt gatagcaata gacatggcct tatcagtctt tgcacgaatc agatccatga
    18781 ctgcctcagc ctgtgttaaa tcaatacggc catttaaaaa agcacgcttt gtaaattcgc
    18841 cgggctctgc cattcgagct ccctgtttaa tgaggagctg taaaatgtca tttgtcaccg
    18901 caataccgcc atgggtattg atttcaatca cgtcctctct ggtaaaggtt tttggcgcca
    18961 gcatgactga taccatgacc tcatcaatca cttcacctgt gcttggcttg ataatatgac
    19021 catagttaag ggtatgtgag gcgactgttg ttagatcttt tcctttaaag atcgatttag
    19081 caatgtccag agccttggta ccagacaagc gaacaatgcc aatagctcct tcacctaacg
    19141 gagttgaaat ggctgcaatt gtatcaaatt ctttagttat actcatgcct tctattgtag
    19201 aacaagtcag catagaaagc aaggtattgc attagctgct cgttgtcgtc attcttgtct
    19261 agtggcaaag cctcaaaagc agttgtaaac agctaaagct atgattaaaa agccttgtat
    19321 ggtaagtaca ggataaagcc aaaaagctga tgagttttag ataaacatac aggctcgaaa
    19381 agccctatta aaccgacagc aacaatcctc acacagtata gttgacttaa ctacctgatg
    19441 tcatttctgg ctgtttttat aatgacaatg gcaatatcgg ttattttgac tatgctgggt
    19501 gcttgtatcc tagtggactg actgacaatc agggcttctt tttcaaccac gaaaacatta
    19561 aaaaagtctg gtttggaggc tatattgacg atagtgaaag agaagctcaa gactttttta
    19621 aaaaagaggc aggctatatt aaatatccta aacttagtat agataatagc actagatagc
    19681 attaatttaa gtatataacg ttatgattat ggttggatta gttcattata cactagcaat
    19741 aaggtagatt attttgttat aataaaatat atacaattat tagagagtta gaaagagtta
    19801 tatggtagta ttacaaaata atagtagcac agctagtgag cgagcgacag ctttggcaag
    19861 aggagtccag gccctctcta gtgctggtgc ggtgagcaaa gatatgaaga cgaccgttac
    19921 tggaaatcgt agtgatgcca gctctgccat tgatttatcg cacaacgttt cagcgcaggt
    19981 agttgggatc atcgcttcta tgtcgcaaca cattcagagt gtctctgcct cttttcaagc
    20041 gatggatctt cagcttggaa aagagttagg gcgtttagaa aacaggcgga ggtttagtct
    20101 caatgaccca aaatgagctc atgtaccaga aggagagatt ggataaacgc ttggaaacca
    20161 tagcccaaga gcttaagcgt aatgaacagc gctttgaaga ctatgaggaa ctatctaacc
    20221 tagcggcaca actgttaaca gcagctgcaa ccacctttcg ttcatcatca gatagtcatc
    20281 tctttgaagg ggctttggca gaagaatgtt atttgaaaag gaaaacacaa gcgtccttgg
    20341 aacaaagtca tgaggagctc ttaggagagc agcgtcgttt gtaccaagaa gaggaagccc
    20401 ttacccgaca attaaagcta gtcaaaggaa aggagagagc taatgagcat tgacatgtat
    20461 ctggggtcat cggaccagca agctagtagc gttggtaagg tcttgcagca gcggataaca
    20521 gcttataagt ctttgcaaag agctttggag caattggtgt cttctagtcc tgacttatca
    20581 gggcatacct atgcttctgc taaaaggtac agcgagcagg tattgatccc tttgatgagg
    20641 ggctgtatcc tgctagatga agccatcaag gaagcctgtg cagcatttcc taatgactac
    20701 cgtcgtcagg ttgatagtgt ggatttgaag gagagtgagc tggtggatca gatcagccgc
    20761 tcagaccgca tcataggtcg ttacgttgag ttgattgatc tggagtatcg gcaggagctg
    20821 ccgaattact cttatattac taatctcaag agcggagcga gtaaccagcg tcaagtcaag
    20881 agaaaattag aagagaagct ccttaagctg cgagagtttg atagcaattc ccgtcacctc
    20941 ttttcgtcta tcgcagcctt agccgaggca gtcaatatag gtatcagaca aaccaagacc
    21001 tcttggaatg ggacaagtca gacgttcact cttcccaggg ctcttgactt agagtggacc
    21061 aaggtagtag aaaagaggtg gacgcaaagg gaggaaaaag cctcgaagct gaagctacag
    21121 caggcagcag aaaaactttc gagagaaacc gggattaagt acgaagatgc ctatcgtttt
    21181 gtgatggacg gtgttctgtc agatgaaaat aagaacaaaa tcaagagtgt aaagaaacta
    21241 gttaagtata caaagggtgg gctgtatatc gtttcctcag gaaggtatta ttggaaacat
    21301 tcaggtaaac attattggaa aaatacacca aacaaaacat ggaatatttg gaaagcatct
    21361 aaaaacgatc ccaattttga caaaggaggg atcaaaggta aacatttttc taaaaaagga
    21421 gcccgttaca cagacttacc tggtatcaag caattgaaga agagtgaaac agtacaatcc
    21481 ctcatttcaa aaatttcaaa agataatcaa gggaagctca ccaaagttgg taaagggtta
    21541 aagaaagttg ataaagagct aagcaacata tcgtcaaaac tcaagtcata tgagcatgga
    21601 cgcctaaata gagacttgaa aatgatgaag gagaataacc tgggtaaaag tctcggtaag
    21661 tttgggaaag ttggaaaagc tgcaagcaag gtgctcaagt ttgcaggaaa aggtctcaaa
    21721 gttgcgggtt gggtaggtgc tgctataaat gttaaggact cggttgaaac ttacaagaaa
    21781 aaaggctata gcaatgagca aactgctgct ttaacagccc gtaaggtagc tgttgatact
    21841 gcaacaactg ttgtcggaag caatattggg cgtgtaacag gtgcagttat tggtcaagca
    21901 gttataccta ttccaggtgt aggtgctgct atcggttctg ttgcaggaag tattttagga
    21961 gctatggcag gtagttggat tggtagtaca attaatgaca atttagataa gaacgtaaaa
    22021 cctaaacaat caggaaggag tttagcatgg taatgttaat gagaacactg ttatttccag
    22081 ttgataacgg acttgattca ggattgactg gtgatggtta tgcagctgag tatgatttgt
    22141 ggactggaaa ggtcacgtgg cgacaacttg gtgatggaaa aataaaaagg caacaaaagg
    22201 tagcagctat aattaatctc attgcagctg caatatctcc acttgtcatc atgtctatca
    22261 tttttacggc aaaaagtctg aagctttttg atgtagatac tagtacaaca atttatcgat
    22321 atgctcctct gatggtaggc ttggtctttt tcttctcgtt tgaattattg atgctggcta
    22381 ttagacgtct gtatccatta gccaaagagg agccaagttt aaagcgtcaa catgggtatt
    22441 ttaagaccat gtatgacaat actatacgtg agaatgatgg tgtttttaat aatttatcag
    22501 taccttttat agggctttat gtagctttct tgattgcctt ttcggttatt ccaatttttt
    22561 actctcaata tctgcagcaa aattcttttt ggtcctattt aggaaattta gtaggaagta
    22621 gcattcttat ttccttagtc cccaattttt tatggaatgt cttagtgaaa caattgattt
    22681 acatcaagct tattcgcaaa acgaaagaaa aaatcttaaa gaatgaaacc taaacaatca
    22741 ggaaggagtt tagcatggta atgttaatga gaaccttgtt atttcccata gataatggta
    22801 tggataataa cttaattgga gacggcttat cagctgagta tgacctatgg actggaaaag
    22861 ttacgtggcg tcagcccagt gatgataaga ttagaaccca acaaaaggta gcatttgtac
    22921 ttaatcttat agctggtagt ttatctccat tagctatatt tttatttgtt attattgtta
    22981 gacgcttagg cgtttttagt ggcgatacta attcaatgat tttcaagtgg gcaccgctaa
    23041 tagttggatt tatccttttt atatcgtttg aattattgat gttggcgctt agaagtagat
    23101 atacgatatt agagaaagag cccgatttag atcgtcaact atactattat cgtacaatgt
    23161 atgataatac tatacatgac aattcaggtg tttttaacaa tttatcagta ccttatgtag
    23221 gtctatacat tactttattt ctaatttttt taatcattcc actttgttat catttttact
    23281 tgcacccatc ttcatttggg gattatctcg ctgcattatc tgtaacaagt ttgttgattt
    23341 ccttatttcc caatttttta tggaatggtg tcttgaagca cgttatatat gtcaaactta
    23401 ttcgccaaac aaaagaaaga attttaaaga atgaaaccta aacaatcagg aaggagctta
    23461 gcatggtaat gttaatgaga acgctgttat tcccagttga taatggcatg ggaacgggct
    23521 tgaccggtga tggttatgcg gctgagtatg atctatggac tggaaaggtc acgtggcgac
    23581 aagccaccaa acaaacaatt gaaaagcaac aagcactaac gtctaacctt ttgattattg
    23641 cctcatgctt atcaccagtt actgttgcag gaatgatact gttgagtaga agtttcccta
    23701 ttttcgagga agacttatca gagaaaattg atacttatgc tccaattatt cttggtgttg
    23761 tgttatttct tgcttttgag acgttaatgc ttgctatcag aggtcgtgat ccattagcgg
    23821 agaaggaacc agatttaaag cggcagcatg actattttga aaagatgttt gattttgcta
    23881 ttcgtagaaa tttgtcgtca gataatctaa aaactcctta tatagctact tattttgctt
    23941 ttggtatttc tttactctgt attccattta gctattatgt ttatctgaat ccggagcaat
    24001 tccctaattt ggattatggt catttatcaa tcctgcttgt aacaagtatt cttatttccc
    24061 tagttcccaa ctttttatgg aatgttctat taaagcacat tatctatatc aagcttattc
    24121 gcaaaacgaa aggacaataa aacattatga acaaaccaga acacatttta ccgattggta
    24181 ctatagtgct gacggagaca ggagaaattc ctttgatgat tgtgagtcgt gcctctcttt
    24241 ttgatgataa tggagaaatc ggctattttg attatgctgc agttccttat ccagaaggca
    24301 taggaaatga taatgagtac cttttcttca accatgagga tattgctgat gtcatctatt
    24361 ttgggtatgt caattccaat gaacagcttt ttgcagaagc ctacgatgat ttggtgaaaa
    24421 catcaggtta tcgtaaatta agcttagatc accatcaata gaaaaaggac atgaagatta
    24481 tctagaaaaa gaaaagaact aatgagcatt gacatgtatc tggggtcatc gaaccagcag
    24541 gctaatgatg tatggccaat attttgagag gatcggcctg ctcctctttt ttgtatgttc
    24601 aaagctataa aaagcttact ttttgaggta taaagcttcg acaatcaaga gtatttgctc
    24661 tggtggcttt aatgatcttg cttatagctt ctggtcagat tgttttagcc tgcttgtgct
    24721 gtctgatcca gatttgactg aggctttgat gacagtcgtg aaggcgggtt taagaatggc
    24781 atgtctaatg tcaatttaca atagagaagg aaaattgatc aaacagtgtg agatattatt
    24841 aacaagtttg cgctttcatg gtataataaa gtgctaggaa gcattttatt ataagataag
    24901 ggggaatcat ggaagcactg aaaaagattg ccggtgtgac tgctgcgcaa tatgtaacag
    24961 atggaatgac cattggatta ggaacaggat caacagctta ttactttgtt gaagaaattg
    25021 gtcgtcgcat caaggaagag ggactacagg ttgttggtgt gacaacctca agtgtaacaa
    25081 ccaagcaagc agagggccta ggtattccct taacatcaat tgatgatatt gactgcattg
    25141 acctgactgt tgatggtgct gatgaggtgg ataaggcctt taacggtatt aagggtggtg
    25201 gagcagctct attgatggag aaaattgttg caacaccaac caaggaatac atctgggttg
    25261 ttgatgaatc aaagctggtg gatcatttag gtgctttcaa gctccctgtt gaggtcgttc
    25321 aatacggtgc tgataggcta tttcgagtct ttgaaagggc tggctataag ccctcttttc
    25381 gcatgaaggg ggataagcgt ctcataacgg atatgcagaa ctttatcatt gatcttaacc
    25441 ttggctgtat cgaaaatcct tgtgagtttg ggcgtctgct ggatcaaact gttggtgttg
    25501 tcgagcatgg ccttttcaat ggtatggttg ataaggtcat tgttgctggt caggctggtg
    25561 taacggtcct tgaagctaat cagtcaacct aattcctagc tcaatcatgt tttacattat
    25621 tttataggtt ttggggagcc aaccgtaacc tcccctagat tggagactta tgtcaaaatt
    25681 taatcgtatt cacttagtcg ttctagattc tgttggtatt ggtgcagcac cagatgccga
    25741 caaattcttt aatgctggtg tagctgatac agattctgac accctcggtc atatttcaga
    25801 gacagctggt ctggctgttc caaatatggc aaaaattgga cttggtcata ttcctcgtcc
    25861 tgtcccccta aagacagttc cagctgaggc tgatcctact ggctatgtca ccaaattaga
    25921 agaggtatct cttggtaagg ataccatgac aggtcactgg gaaattatgg gcttaaacat
    25981 tactgagcca tttgatacct tctgggatgg ctttccagag gagattatcc aaaaaatcga
    26041 agctttttca ggccgtaagg tcattcgtga agccaataag ccttactcag ggacaaaggt
    26101 gattgatgat tttggtcccc gtcaaatgga aactggtgag ctgattgttt atacctctgc
    26161 cgaccctgta ttgcaaattg cagcacatga ggaggtgatt cctgttgagg agctttaccg
    26221 gatttgtgag tatgcgcgtt ccattaccct tgagcgtcct gctcttttag gtcgtattat
    26281 tgcccgtccg tatataggag agccaggcag cttcactcgc acagctaatc gtcgtgatta
    26341 tgcagtctca ccgttccaag acactgtctt aaataagctg gctgacgctg ggatttctac
    26401 ttatgctgtt gggaaaatca atgacatctt taatggctca gggattacca acgatatggg
    26461 gcacaataag tctaacagtc atgggattga taccctgatc aaaaccttgc agttgccagc
    26521 atttacaaaa ggtctttctt ttactaactt ggttgatttt gatgctagct ttggtcaccg
    26581 tcgtgatcca gagggctatc gtgactgttt gcatgaattt gatcgtcgcc tgccagagat
    26641 cattgccaac atgaaggacg atgatctgct cttgattaca gctgatcatg gcaatgaccc
    26701 aacctatgct ggaactgacc acacacgtga gtatattcca ttgcttgctt actcagcctc
    26761 ctgcactgga gcaggtgtga ttccacaggg acattttgct gatatttcag cgactattgc
    26821 cgaaaacttc ggtgtggaca ctgctatgat tggaacatca ttcttagctg acttggtata
    26881 ggagtaagca aatatcattt gataggccaa ggagcttggc gtatcaaatt gaaaaccagc
    26941 gctgtggtta ggtctattaa taggcttgtg gcaggttgtc tagttctgat gatcggtgtg
    27001 atattagttg atttattgga ctttgctaca gcaaaaagct caagagaagt atgctttata
    27061 gtaaaaaata aataagataa agggagaaat aagatgacat tacttgaaaa aattcgtgaa
    27121 acacaggctt tcctagaaag caagggcatt gataagcctg aatttggtct cattttaggc
    27181 tctggtctag gtgagcttgc caatgaggtt gagcaggcga ttgtgattga ttatgctgat
    27241 attccaaact ggggcaaatc aacagttgtt ggtcatgctg gaaaattagt ttatggtgag
    27301 ctggctggtc gtaaagtatt ggcacttcaa gggcgctttc atttctatga aggtaatcca
    27361 atggaggttg tgaccttccc ggtacgtgtg atgaaggctc tgggctgcca tagcttgctg
    27421 gtgacaaatg cagcaggcgg tatcggctat ggtcctggga cgcttatgct aatcaatgac
    27481 catattaata tgacaggaac aaacccgctc attggtgaaa acctagatga atttggccca
    27541 cgcttcccag atatgtctga tgcctataca gcagcttatc gtgagacagc tcgctcagta
    27601 gcagaaaaac taggcttaga cctgcaagag ggtgtttacc ttggctgttc aggaccaacc
    27661 tatgaaacac cagctgagat tcgtgccttt aaggttatgg gagcagatgc tgttggtatg
    27721 tcaactgttc cagaggttat tatcgctgcc cactcaggct tgaaggtgct tggaatttca
    27781 gcgattacaa actttgcagc gggcttccaa tcagagctta accatgaaga ggttgtagag
    27841 gtaactgagc gtatcaagga aaactttaaa ggcttggtta aggctatttt ggcagagctt
    27901 taaggcttgc tcttagacta gcagtaacca tgagcgactg ctagtacttt gatcgataag
    27961 acgaggaaaa ataaggattg ggacattaga gtgatgactg atatggaaca tacgataagt
    28021 attcttttag aagtttatgc ttatagtcat gcctacaaaa ttgcaagaac tctgcctgat
    28081 ttttccccca aggtacttta tttgcttgag cttttaaagg aaagaagaga gcttaacgtt
    28141 gcttatgcct ttcaacatag ggcggaaaat aggcttattg aggatagaca tcaggttaag
    28201 cttttgttaa atgaagctca agaggaggag cagactgcaa attacctgct tgatttggca
    28261 gctaaggtca aaaacggtga gattattgat tttgtaaggt cagtatcgcc tgtcttgtat
    28321 cgtctctttt tgcggctgct tgagcaggct gtcccagatg ttcaaagcta tattattgat
    28381 accaagaatg atcaatatga cacttggaat tttaaggcga tggaaaaagc cgataatgac
    28441 ctctttagga gctatctggc acaaagacag ccacgtcatg tgacgacacg cagcttggct
    28501 gatttacttg ttttatcaga gcttccagct gatattaaaa gactagtggt agtcttaagg
    28561 cagtttgaaa aatcagtccg caatccccta gcacatttga tcaaaccctt tgatgaggag
    28621 gagctatatc ggacaactca tttttcctct caagcctttc tagatggttt gattcgctta
    28681 gcagtttttt ctggtgttaa ctatatcaaa gagcccttct attttgatgt cgttaatgct
    28741 gtcattgaaa aggagctgtt agacagcgcc aagccttagc tatttgaaag attagcaata
    28801 ataaaaaacc tgaacgatct gaacgaggct tctctaagct agctatgact agtcagctta
    28861 gagccttaga acaggtcttt caggtttttt atgtttagct agtgtggtta attaatgatt
    28921 gaagctaatt tcttctagca ggtagtcaat aaatcgctct cccatttttg agaggttagc
    28981 cttttcgtgc ttgataaaga caatctcaat cacatcaggg acatctaagg gaatagcgac
    29041 aatctggtct ccatttagat ttgtgtttaa aataccgctg gcaacggtgt agccatttaa
    29101 gccaatcatg agattaaata gagtagctcg gtcactcacc acaatagact tactgtgagg
    29161 gatatgtgcc atcatctcct ctgagaaata aaaggaattg tgaatcccct gatcatagct
    29221 tagataagga aaatcaagga gatcatcaat ggttaagctg gttttatttg ccagaggatt
    29281 ggacttgctg ataaagatat gcggtgtggt tttaaatagg gtggaaacgg tcaaatgatt
    29341 ttcctcaaac agcttggtaa ggacgtctcg gttgtagtca ttgataaaca aaacgccgat
    29401 ttctgagcga aaatttttca catcgtcaat gatttcccag gttcttgttt ctcgcaagaa
    29461 aagctcgtac tgggtcatat cagcccgctt taataaagag acaaaagcat tgacaacaaa
    29521 ggcgtaatgc tgagaggaaa cactaaagag ctcacgacta gtattgtgat ttttatagcg
    29581 atcctctagc agtgctgttt gttcaataat ttgtctggca taagatagaa actcaacccc
    29641 gtccttggtt aaggtaatgc ccttgggatt acgaatgaaa atagtaatgc ccatctcctg
    29701 ctctaattcc ttgacagcat tagacagact gggctgcgtg ataaataatt gcttagcggc
    29761 ttcgttcatg gaaccgcatt caacaatctt tataatgtat tgtagttgtt ggattctcat
    29821 actgacagtc tatcttaaat agtacaaaga atcaagtgcc tttattagag cttaagacaa
    29881 ggtttcacaa gcggtagcct agcttgtgcg gtgaagctag cttgatgcta gtgttgtacc
    29941 caggtaaaaa agagctggca aataggcagt tttatcgctt tttaccgctt atttttggca
    30001 tgcctgtgtt ttgataaacg gctggtcttg atcggtaaaa agtaatcgtg ataatatcag
    30061 ataataccta tttttccatt gctcttttaa ttttcttgtg ttatattaat aatattgata
    30121 tatttaatgt tttgagataa agggtggtga tggtgtaata tgactggaca aagtagtcat
    30181 caggtattaa ttcaaaagct gttggtcagc actcactatt tgacattatt tagagatgag
    30241 ctgaagctag ttgagaggac accatctatt ttgggaagtg agtttcctgt ctctcttgtt
    30301 caaacggaat taggtgatat tatcaccttg gtggatacct taaataagca gcagcgcttg
    30361 attgagtcga ccttttggta tgaggagtca gcctttaagc tcatgaacaa ggccttagat
    30421 attgttgata attggataaa ggggatagat ggcttaatta agctctgcca gtccaaggag
    30481 gtctttcagg ccattgttgg tgataaaaga acacgtgttt ttggtgtttt gattgatgtt
    30541 ttttcttccc taaaaattag caccatgtca ttgaaggaat ttgcagctcc ggctgctctt
    30601 tgccattaga ttaagctggg ctaagcttgg atagtggctg gttaagcctg caagttgccc
    30661 ctctcatgac aagtctaggc tttatttagg gtgagcagtg tgccaagggt gtattaagtg
    30721 ctggttgctt tgaagcttcg ccttgctagg ttagctgtga gtgatgtcac gataactgcg
    30781 cgaaacagtt atttctgaat tataatacag gttaaagtag gtacttttaa tgtttttcct
    30841 attgtaaaat ctatacaaaa taggatatat
//
LOCUS       DARYLD010000022        30555 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYLD010000022 DARYLD010000000
VERSION     DARYLD010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30555
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            116..328
                     /locus_tag="TU651_000856"
     CDS             116..328
                     /locus_tag="TU651_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL0896868.1"
                     /translation="MSQQHRKWSALVEQRLKEKDWTKGDLALAVGLRSSGTITDLLAK
                     GKGSVDLKVRVSKILGIREPWELFER"
     gene            401..652
                     /locus_tag="TU651_000857"
     CDS             401..652
                     /locus_tag="TU651_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896869.1"
                     /translation="MDNILMSLSDWIKEIIEKTVNRLVQIKLDEANAELLTREKVADR
                     LNMSPATFDKYYRYDKNFPSELPGVRWKKAEIIAWLNNK"
     gene            928..1269
                     /locus_tag="TU651_000858"
     CDS             928..1269
                     /locus_tag="TU651_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896870.1"
                     /translation="MTQAERIREFYKENPTASYDEVAEAIGTTNSNVRANIAKDIKAG
                     RCVRLEDKSLDYSAHFGATEALADLVDWKNDTRREWVEMLTRAAEKETDSNTMRLLIK
                     EANKLMKEVTK"
     gene            1269..1751
                     /locus_tag="TU651_000859"
     CDS             1269..1751
                     /locus_tag="TU651_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEL0896871.1"
                     /translation="MAKLYELVGEYRDLYELNLDDETLKDTLDSIDWADRLSEKVEGY
                     AQVIETALAEAKMFEEAEKKFKAKKEAAKKKAAWLQGNVFDAMKLTNQTEIKSGIFTV
                     RIKQNPESVKVDEELLPKKYFNKKITVAPDKTTLKELLKSGKKIKGAELIRTEKLVIK
                     "
     gene            1748..2221
                     /locus_tag="TU651_000860"
     CDS             1748..2221
                     /locus_tag="TU651_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896872.1"
                     /translation="MMILAIDPSSNRIETSTTGIVLLDNARLVDYWVVPFGAENFKKW
                     FKDIGRTLEFDTVVVEKFEVRDNDYSRDNSVVETISAIELCYPDLVLQRNAGYQTDIP
                     NGLLKALGLWSFDKSHHNDVRAAARLGLFWAQRNDIEEVIVDIGNRITQMASGSS"
     gene            2181..3356
                     /locus_tag="TU651_000861"
     CDS             2181..3356
                     /locus_tag="TU651_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896873.1"
                     /translation="MAIELRKWQAEAVKRSDRDCPGIFLEAYGGRGKTICAFEIAKHK
                     EAKKVLVINNRLAILNGWNNTHQDLGYVNDFELEIMTDRRLQNRLASGESIECDVFVI
                     DEWQNMSSDANVKAYKKVKRGYTVGLSATPIRKKGQNFYPLEKTIFGMAEPNQRENWQ
                     LAHGKMKYSKFSYSKQEWDDFRNYESYVANLPNFFRWEDVEAIEEAEENNGFEVIFEP
                     VWCPPANPKELEQFRSLNIVGKDGKFAMAKQTFGRKIFERYLIQTGFEIDFPKLKAIN
                     ADTPMLIQLDLLLASHTEMLIVSKSKQIVEVIRERHPEIGIWTGDKKDALEQTNVVAT
                     TQVLGVGVDGLQYKFKTIVVLDPVNPSDGDYDDYRQLLWRVTGSRQQHDVRVIEFYF"
     gene            3366..4076
                     /locus_tag="TU651_000862"
     CDS             3366..4076
                     /locus_tag="TU651_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEL0896874.1"
                     /translation="MAEHKESGIFIVLRCIQADLIAPKGQYNSFGKYAYRSAEDILEA
                     LKPLLKKYDASIVLSDEIVQVGERYYVEATATLYAMGECVGNKAYAREDETKKGMDGA
                     QITGAASSYARKYALNGLLAIDDNNDADTDAYHNQNNQSAGKTQKTNQKQASQQESTA
                     KAPAKNNGSKTITGAQAKAIRTELKNMAEATGSPAAAIGNWFIGKMGVDKPENIPAER
                     LKEAQQIIADAKKVKGIE"
     gene            4077..4469
                     /gene="ssb"
                     /locus_tag="TU651_000863"
     CDS             4077..4469
                     /gene="ssb"
                     /locus_tag="TU651_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0896875.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGVLIGITGRIQTRNYENQQGQRVYVTEVVADNFKM
                     LEYRQQQQQEDSFDNNNPMDIQADDLPF"
     gene            4483..5310
                     /locus_tag="TU651_000864"
     CDS             4483..5310
                     /locus_tag="TU651_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEL0896876.1"
                     /translation="MGMKEYALAYQKKGFSVLPISPTGKKPMIAFADKPPMTAQEIED
                     FWTQYPDSNIAVRTDKFFVIDIDLHGKANGFESLANWEHLDLITPTLQAKTASGGKHI
                     FYFKHPDVSMTQMIGFLPGVDVKAHLNNYVLVAPSKTPKGVYAWDKDKSKEDGTMVTA
                     SRKLVMAIKQEYNKKNPGSDLDNIYYQISKGAGKRNRTTELFEMIVLGFGDQGGRNDT
                     LARFVGGLLSRSVDPECILRLAETANNNSVEPLGKREMRRTIESMIKKHMRGGGHNR"
     gene            5294..6694
                     /locus_tag="TU651_000865"
     CDS             5294..6694
                     /locus_tag="TU651_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL0896877.1"
                     /translation="MATIGEIVNISIKQFSRRKKKILSEEGEQIEVESIVADSPRNVL
                     LAMKSDNKLNDFLRHNEFTGEHEIVEDVKLDAIQLRRGQLPSTFESYLSVYLENHFKT
                     VFKAGALRDGIEAFFAEKTYNPVQEYMEHAYESWDHRERLAQVFQTWLGAEDSIFVQR
                     IAVMFFVGAVSKVFNPWVKFDYTLDLVGGQGAGKTTFLQKVAVEWYTDSAKDFMDKDN
                     YEIMLKSLIVNDDEMVASRKTTFDELKAFVTKTELSFRRSYGRRAEKFPKNFVIARTS
                     NKVEYLGDKTGERRFLPVLVDADQQLVKPFDMTDRDVLQLWGEAVAIYKKGFTLTFDD
                     DFEDELAVYKERFTYKDEAESQIYDYLDMLVPDEWEEMSVVQQHQYTWAYFNNGSYRN
                     ESGFVYEGVKLQASVSAKQILKNVFDIDSARGERIARKIKLIMDNHQDWEYRIKKIKG
                     RTVRAYFKKNMQNEVM"
     gene            7050..7244
                     /locus_tag="TU651_000866"
     CDS             7050..7244
                     /locus_tag="TU651_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896878.1"
                     /translation="MSYKVLVYFDNMLDEEYKFKTEKDASKCHDQLRRKYQGQRLYKV
                     KMEEVEEEVIITNFREVDHD"
     gene            7237..7464
                     /locus_tag="TU651_000867"
     CDS             7237..7464
                     /locus_tag="TU651_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896879.1"
                     /translation="MTKDDFLTGFVLILLAACIFAVGFAIGHDYSSEHYEQKITDLQI
                     QLVSTQQQLKQSREQNQSQTKRIANLTGNGG"
     gene            7475..8164
                     /locus_tag="TU651_000868"
     CDS             7475..8164
                     /locus_tag="TU651_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0896880.1"
                     /translation="MEIKCGNCLELLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGADLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLAVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVSGAEKTQH
                     PTQKPVALMRDIITRHTTKRAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAN
                     KRIAELTGNGG"
     gene            8166..8957
                     /locus_tag="TU651_000869"
     CDS             8166..8957
                     /locus_tag="TU651_000869"
                     /inference="COORDINATES: protein motif:HMM:TIGR00675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL0896881.1"
                     /translation="MLRVFEAFAGIGTQRMALRNLGIPHEVVAIAEIDKFAIKSYEAI
                     HGPVNNLGDISKINPDTIPDHDLFTYSFPCQDISVAGKQAGLDIDSGTRSGLLWECQK
                     VIVAKKPKYLLMENVKNLVGKKHKPNFDKWLDWLESQGYTNDWQVLNAKDYGVPQNRE
                     RVFCVSILGEHKPYIFPEKQELTIRLKDILEDDVDEKYYLTTNKANELLATIVRENDV
                     SERVVVDSTIKKPKIKNVMNAVIGRYDAGIRNQQSVGGAVIELIE"
     gene            8899..9444
                     /locus_tag="TU651_000870"
     CDS             8899..9444
                     /locus_tag="TU651_000870"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEL0896882.1"
                     /translation="MQASEINNRLEVLSLSLLNKNATKKGYLVADDGDGIDTAYPDSK
                     TRKGRVQKNMSHTITTDDSKAFLIGASRGRDPENPNDRSAGNQNLQQRLEINKNGTSN
                     TITSVQKDNYAVEFPDYRIRKLTPLECWRLMGCSDEDFEKAQSVNSNSQLYKQAGNAI
                     VVDVLEAILKQLFLTEAQNEH"
     gene            9434..9952
                     /locus_tag="TU651_000871"
     CDS             9434..9952
                     /locus_tag="TU651_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0896883.1"
                     /translation="MNIEEAKQKLHNMAYRDLQTKPYDLKLADVIQILNQIKLDKPQP
                     EIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFEKQETFVNAFLYGYTIEKE
                     KLYTVEIPNPKNGIAHRHIMLVKTTDGRVVLSEVVDSHIHLRDDLRLTESEIRKDFDW
                     AWREEFPKEVTE"
     gene            9979..10278
                     /locus_tag="TU651_000872"
     CDS             9979..10278
                     /locus_tag="TU651_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896884.1"
                     /translation="MNYDKKKSDLKKRLIIGFTLLPISIVLSGFVIKYGWNNILSTID
                     GVPPINLPQAIAIDVLVSFIIAKTNAEGDFATEVGRAFISPLMTLLLFWVVTLFM"
     gene            10295..10468
                     /locus_tag="TU651_000873"
     CDS             10295..10468
                     /locus_tag="TU651_000873"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896885.1"
                     /translation="MTEELGVLLDKEGVEYVKMVFDDGFVWTIRNPLNAALLKRQDAE
                     QFPQFTWVPLTDL"
     gene            10805..11245
                     /locus_tag="TU651_000874"
     CDS             10805..11245
                     /locus_tag="TU651_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL0896886.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVPSKPVERLALNRVSAEQELDAIERAVNGIFDPEYRLILIDKYLLTYPKTD
                     CDIYTKLGYEKSQYYNMLDNALMSFSELYKEGMLLVEKMEKSWN"
     gene            complement(11643..12020)
                     /locus_tag="TU651_000875"
     CDS             complement(11643..12020)
                     /locus_tag="TU651_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL0896887.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(12072..12257)
                     /locus_tag="TU651_000876"
     CDS             complement(12072..12257)
                     /locus_tag="TU651_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL0896888.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            12373..12708
                     /locus_tag="TU651_000877"
     CDS             12373..12708
                     /locus_tag="TU651_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL0896889.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            12871..13338
                     /locus_tag="TU651_000878"
     CDS             12871..13338
                     /locus_tag="TU651_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL0896890.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            13353..15107
                     /locus_tag="TU651_000879"
     CDS             13353..15107
                     /locus_tag="TU651_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL0896891.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKKVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            15104..15274
                     /locus_tag="TU651_000880"
     CDS             15104..15274
                     /locus_tag="TU651_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896892.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            15267..15533
                     /locus_tag="TU651_000881"
     CDS             15267..15533
                     /locus_tag="TU651_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896893.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEALRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            15567..16787
                     /locus_tag="TU651_000882"
     CDS             15567..16787
                     /locus_tag="TU651_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0896894.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAHISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            16765..17430
                     /locus_tag="TU651_000883"
     CDS             16765..17430
                     /locus_tag="TU651_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL0896895.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            17455..18642
                     /locus_tag="TU651_000884"
     CDS             17455..18642
                     /locus_tag="TU651_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL0896896.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASIEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEALRFEGKDEVLIPLNQTTPVAPDTDGIKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKASGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQSMDTLKDENGRYLLQDSITSASGKVFLGKPVFVLSDDVIGKD
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            18787..19089
                     /locus_tag="TU651_000885"
     CDS             18787..19089
                     /locus_tag="TU651_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0896897.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            19086..19433
                     /locus_tag="TU651_000886"
     CDS             19086..19433
                     /locus_tag="TU651_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL0896898.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            19430..19807
                     /locus_tag="TU651_000887"
     CDS             19430..19807
                     /locus_tag="TU651_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0896899.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            19804..20229
                     /locus_tag="TU651_000888"
     CDS             19804..20229
                     /locus_tag="TU651_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896900.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLINVRKYRYFDFY"
     gene            20245..20835
                     /locus_tag="TU651_000889"
     CDS             20245..20835
                     /locus_tag="TU651_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0896901.1"
                     /translation="MGKVKFGLRDFQYAVLGDDDQLKTKTGGIKSLPGMKSAKLDITN
                     ELVTVAADDGPYVVLSGGITETKLEIEVLDLTSDARKDFFGIKEEDGIEKYNKELTPN
                     DVACMFRTSDENGKAIWIGLLKGKFNIPGMEMQTKEGAPDPKSDTVTGNFVSRGKEGD
                     VIVIGRESASGFKLEKFKEFVFAGATDIKKGENFEM"
     gene            20887..21213
                     /locus_tag="TU651_000890"
     CDS             20887..21213
                     /locus_tag="TU651_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896902.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            21261..21410
                     /locus_tag="TU651_000891"
     CDS             21261..21410
                     /locus_tag="TU651_000891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896903.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            21423..25082
                     /locus_tag="TU651_000892"
     CDS             21423..25082
                     /locus_tag="TU651_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL0896904.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRSLATETSVFTRFGKAAERIGGKMKSFGDSVAGVDAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGVKTGDILSFSRTMIYLGESTNLSAEEAATSIAKIANITGLASSEY
                     SRFGSAVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQSLSAIERAVASGGDNLNKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDDLGLSGIRQSNMLKSLGLASETLGKALDTSNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIVKWGLIAAAAGPALSIFGKGVGIIGGTIQAMGKMSRGLGTLSGWLRTFRTGA
                     VAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGIKVSQVQANELQRFKNKVDEANLAMTTFGVRSANNLDKIKTSFKALADEIEALQNK
                     KLKKDLKLAEKLGLSQETIEEIRRQADQTVATVRGMSDKVVDIYRRAKEERRSLTEEE
                     KTVVTKNLNDMIQTELSLMNYSKKEKIAILKAMNGEIETLNYEQLKKAQEVAQKMIES
                     ENKTYKKRRSNLKEMYDNIKGDSETAVRAREEIHRQLETLEDSHTAKMESLGERYLKI
                     RKKLLEDPALDPRVKQAMIDSLDKEFEKLGLSFEKLSKRSEEASSKTKISMQDMTSSF
                     RASIGEAISSLQGWDNLTPQEKQLLIDGNKAVSEILNSKTLLEQWQALTPQQKELLAK
                     NLTQDPTLSAQQAIDNVKQRVPADVKASDKTAPDVASADRAVNRPKQKGPAIIRAQDN
                     ASSVASGVIGWLNSIPRTVTSTITTIVRKITGHKTGTDYHPGGLAMVNDQKGPLYREL
                     ITLPTGESFIPEGRNVILPLPRGSKVLRASRTKQLFSHYANGIGFNDTKIASLTTRLK
                     SVQDKGQVIVNTDPQLAELIKLLKDRDNRNVTNNYTLNATNRSNSDDMFNQENMRRLL
                     RELAYYTNGEKGRLA"
     gene            25082..25789
                     /locus_tag="TU651_000893"
     CDS             25082..25789
                     /locus_tag="TU651_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0896905.1"
                     /translation="MRYIEFNGKKSDSFGLLLERERSIKSTSNDVDLIEVDGRDGVLL
                     KDNGRLKAIEQDFPFSLVGDVAVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVSLVNGGTLQNLGNVQSKPILKIKGTGN
                     GVLTINGFETGLENVQGELIIDMERHLVYKDILSAWDNIVRTERHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            25786..27927
                     /locus_tag="TU651_000894"
     CDS             25786..27927
                     /locus_tag="TU651_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0896906.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVRVTRERNGNYSLYIKYP
                     LDGVFASVFKEELKIKSDAGRRTKWQTFEINRVLRNSKDHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKAPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEQEQPEEQLVTLPEFILDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQRELDERNQKELEEFRETLKNLSL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDPNRVKKIDEDFIEVEANDGGFRRGETYTISFSQTCELLKKVAITLTQANNKGVKL
                     VLIPTKAKMEAQTFNLSKDKEVISVYPLSYRAVLTGDWYKSKQIELNAAEVQNLALEM
                     SYRDVVDSNNASLILDWSPNPDVIFDGNGGS"
     gene            27927..28688
                     /locus_tag="TU651_000895"
     CDS             27927..28688
                     /locus_tag="TU651_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0896907.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGPQGPQGLSGDRGPIGQTGPQGKQGVSVQSASVDSEGYLTVLL
                     DNGQSFKSDSSLKGSKGDTGPKGADGKMTFEQLTPEQKQQLKGDKGDPGPKGDIGPRG
                     ATGPQGPKGEPGINGMDGPRGATGPRGLQGPLGKDAVLPDDVVRRGELAAYLLRSEYK
                     AKGSGSGLSYKVVTQSEYDDLYDYNDNELILVTEG"
     gene            28690..29307
                     /locus_tag="TU651_000896"
     CDS             28690..29307
                     /locus_tag="TU651_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896908.1"
                     /translation="MAYKLYTKADVGDNMLLVAGRPLPDDTKRLKIQRETLDVLTITH
                     YGSYDMVHLKSTVKKAYSKNTVVTPVSAAASKPKAKPKHVLNFAKANKVYIGSTRVIA
                     VYLGDRLIWSDKHSSGTKTVSVVGSLDIRQSQKMLYLYLIAPDVADVKSKRIKSIAIN
                     GVKLSSTAQISFEGSSYYYLVTIKQVANIKEIKNIASKNKITLEF"
     gene            29318..>30555
                     /locus_tag="TU651_000897"
     CDS             29318..>30555
                     /locus_tag="TU651_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0896909.1"
                     /translation="MSRDPTITLDESNLVIGQDGRMHYTFVAQDDNQKVRLASNCLGT
                     AHFNQLMIERGGQATDYVAPVVVEGSGKPTGLFKDLKELSLELTDTANSQLWSKIKLT
                     TNGMLREYHRDHIKTEIIESADGIAKRIADDTGQKLALINETINGIRREYQDADRQLS
                     ASYQAGIDGLKTQLANDKIGLQAEIKLSAQGLSQKYDDQIRQLYSKITTTSSGTTEAY
                     ENKLEGLRAEFTRSNQGLRTELESQISGLRSVQQSTASQISQEIKDRTGAVSRVQQDL
                     NSYQRRLASAEGNYSSLLQTVKGLQSTVSDPKGKIQSQFTQLQGQIEHRVTRDGVMSI
                     INESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDA"
BASE COUNT        10246 a         5199 c         7096 g         8014 t
ORIGIN      
        1 agtaggaggt gagaatttgg ataatttaca aagacgttta gaacattttg taatcagagt
       61 atcgagacat tgcaacctca cgtttttatt ttaattatat cagaaaggag aataaatgag
      121 ccaacaacat cgaaaatggt cagctcttgt tgaacagcga ctaaaagaaa aagattggac
      181 caaaggcgac ttagcactag cggttggttt gcggagttcg ggaacaatca ctgacttact
      241 cgcgaagggt aaaggtagtg ttgatctaaa ggttagagtt tcaaaaatcc ttggaattcg
      301 tgaaccatgg gaattatttg aaaggtaaca aaaaagtccg acgggaatcg gactcaaaac
      361 aaaaatttac tacttagatt atatcacaaa ggagctaact atggacaata tcttaatgag
      421 tttgtccgac tggataaaag aaattattga aaaaacagtt aacagattag tccaaatcaa
      481 attagatgag gcaaatgccg aattattgac tagagaaaaa gtagcggaca ggcttaacat
      541 gagcccggct acttttgata agtactacag gtatgataaa aattttccaa gcgaattgcc
      601 aggcgttcgt tggaaaaaag ctgaaattat cgcctggcta aataacaaat aagacttttg
      661 gacgaggtct aatcacaagg gaagaaacac tggaaaacaa ttaggagtgt aattatgttt
      721 aataaaaaga aaaaattgca gaagtcattc aataatatta acaagcacat tgatagtctg
      781 acgctgtcag aacaagaaaa gcgtaatcta aaaggattgc tccgtaatgt caaaattaga
      841 acaagggtgg cgtgatgaat gcaattggta tgtatagcat tttagagcgg ctagaccggc
      901 ttgaaaaaat cgtatttgaa acagtagatg acacaggcgg aacgcattag ggaattttat
      961 aaggaaaatc ccactgccag ctatgatgag gtggcagaag ctatcggaac gactaatagc
     1021 aacgtcagag ctaatatagc caaggacatc aaggcaggca gatgtgtccg cctcgaagat
     1081 aaatcattgg actactcagc tcattttggg gcaacggaag ccctagctga tttagtagat
     1141 tggaaaaatg acactagacg ggaatgggtg gaaatgctga ctagagcagc agagaaagaa
     1201 acagatagca ataccatgcg attgcttatc aaggaagcta ataaactgat gaaagaggta
     1261 acgaaataat ggctaaatta tacgaactcg ttggggaata tcgggattta tacgagttaa
     1321 atcttgatga tgaaacctta aaagatacgc tagacagtat tgactgggca gacagattgt
     1381 cagaaaaagt tgaaggctat gcccaggtta tcgaaacagc acttgctgaa gcgaagatgt
     1441 ttgaagaggc tgaaaagaaa ttcaaagcca aaaaagaggc tgctaagaaa aaagccgcct
     1501 ggttgcaagg gaatgtcttc gatgccatga aattgaccaa ccaaacagaa attaagtcag
     1561 gaatttttac agtgcgaatt aagcagaatc ctgaatcggt aaaagttgat gaagagttac
     1621 tgccgaaaaa atacttcaac aaaaagatta cagtcgctcc ggacaagaca acgttaaaag
     1681 aactgctcaa atctggaaag aaaatcaagg gagcagaact aatacgtaca gaaaagttgg
     1741 tgattaaatg atgatactag caattgatcc aagtagtaat cgaattgaaa ctagtacaac
     1801 aggaatcgtc ttactagaca atgcaaggct agttgattat tgggtagttc catttggtgc
     1861 tgagaacttt aaaaagtggt tcaaagatat tggcagaact cttgagtttg ataccgtagt
     1921 ggttgaaaaa ttcgaagtta gagacaacga ttattccaga gataattcag tagtcgagac
     1981 tatatcagca atcgaattat gttatccgga tttagttctg cagagaaatg caggctatca
     2041 gacggatatt ccaaacggtt tgcttaaggc tcttggtttg tggtcttttg ataaaagcca
     2101 tcacaacgat gtgagggcag ctgcaaggtt gggattgttt tgggctcagc gcaacgacat
     2161 tgaggaggtg attgtggaca ttggcaatcg aattacgcaa atggcaagcg gaagcagtta
     2221 agcgtagcga ccgcgattgt cctggtatct ttttggaagc atacgggggt aggggtaaaa
     2281 ctatttgtgc ttttgaaatt gcaaagcata aagaagctaa gaaagtactt gttatcaata
     2341 accgattagc tatcctgaat ggttggaaca acacccatca agatttaggc tatgtaaatg
     2401 attttgagtt agaaatcatg acggatcgca gattgcagaa cagattagca agtggtgaat
     2461 ctatcgagtg tgatgtattt gtcatcgatg aatggcagaa tatgtcgagc gatgccaatg
     2521 tgaaagcata caagaaggtc aaacgcggct atacagtagg gctttctgca acgcctatca
     2581 ggaagaaagg gcagaatttc tacccgttag aaaaaacaat atttggaatg gctgagccta
     2641 atcaacgtga gaactggcaa ttagcccatg gtaagatgaa gtattccaag ttcagctatt
     2701 ctaaacaaga atgggatgac ttccgaaact atgaaagcta cgtggccaat ttaccaaatt
     2761 tcttccgttg ggaagatgtt gaggccattg aagaggcaga agaaaataac ggttttgagg
     2821 taatttttga accagtttgg tgcccacctg ctaatccgaa agagctggaa cagtttagaa
     2881 gtctaaacat cgttggtaaa gatggcaagt ttgcgatggc taagcaaact tttggtcgaa
     2941 agatttttga gaggtactta atccagacag ggtttgaaat tgactttccg aaattgaagg
     3001 cgatcaatgc agatacacct atgctaatac agcttgattt attgttggcc agtcatacag
     3061 aaatgctgat agtcagcaag tcgaagcaaa ttgtagaagt cattcgtgag cgtcaccctg
     3121 agattgggat ttggacggga gacaagaagg acgctctgga gcaaaccaat gtagtagcta
     3181 ccactcaagt acttggtgtc ggtgtggatg gcttgcagta taaatttaaa acgattgttg
     3241 tcctagatcc agtcaatcca tctgatggtg actacgacga ctaccgccag ctattatggc
     3301 gggtaacggg cagccgtcaa caacatgacg tgcgtgtcat tgaattttat ttttgaggag
     3361 acaaaatggc agaacataag gaatcgggta tctttattgt tttgcgttgc attcaggctg
     3421 acctaattgc tccaaaaggg cagtataact cttttggtaa gtatgcctat cgtagcgctg
     3481 aagatatcct ggaggctctc aagcctcttt tgaagaaata tgatgcctca atcgtactga
     3541 gcgacgaaat cgtccaggtt ggggagaggt actatgtaga ggctacagct accctttacg
     3601 caatgggtga atgtgtagga aacaaggctt acgctcgaga agacgagacc aaaaaaggta
     3661 tggacggggc acagattaca ggtgcagctt ctagctatgc tcgtaaatac gctttgaatg
     3721 ggcttttggc tattgatgac aataatgacg ctgatacaga tgcctatcat aatcagaata
     3781 atcaaagtgc tggtaaaact caaaagacta atcaaaaaca agcgagtcag caagagtcaa
     3841 cagcgaaagc tcctgctaaa aataatggtt ctaaaactat tactggagcg caagccaagg
     3901 ctatccgaac agaactcaaa aacatggcag aagctacagg aagtccagct gctgcaattg
     3961 gtaactggtt tatcggaaag atgggcgttg acaagccaga gaacattcct gcagagcgtt
     4021 tgaaagaggc acaacagatt atcgcagatg cgaaaaaagt gaaagggatt gaataaatga
     4081 ttaataatgt agtactagtt ggtcgtatga ccaaggacgc agagcttcga tacactccaa
     4141 gtcaggtggc agttgctacg tttacacttg ctgttaatcg cgcctttaag agccaaaatg
     4201 gtgagcgcga agcggatttc attaactgtg tgatctggcg tcagcaagct gaaaatttag
     4261 ctaactgggc gaaaaagggt gtcttgattg ggattacagg acgtattcag acccgtaact
     4321 acgaaaacca acaggggcag cgtgtgtatg taaccgaggt tgttgcagat aatttcaaaa
     4381 tgctggaata ccgccagcaa cagcagcaag aggattcatt cgataataac aatccaatgg
     4441 atattcaggc tgacgacttg ccattctaat aggaggtact gaatgggaat gaaggaatat
     4501 gctttggctt atcaaaaaaa aggattttct gtattgccca ttagtccaac tgggaagaag
     4561 ccgatgattg cttttgcgga taagccgcct atgactgccc aggaaattga agatttctgg
     4621 actcagtacc cagatagcaa tatcgctgtc cggacggata agtttttcgt cattgatatt
     4681 gacttacatg ggaaagctaa tggatttgag agtttggcca attgggaaca cttggatctt
     4741 atcactccaa ctctacaggc caaaacggcc agcggtggca aacatatctt ttatttcaaa
     4801 catccagatg tgtctatgac gcaaatgatt ggcttccttc cgggcgtcga cgtcaaagct
     4861 catcttaata actatgttct ggtggcaccg tctaaaactc ccaaaggtgt ttatgcctgg
     4921 gataaagaca agtcaaaaga ggatggcacc atggtcacag ctagtcgaaa gttagtcatg
     4981 gccatcaaac aagagtacaa caagaaaaat ccaggtagtg acctggataa tatctactat
     5041 caaattagca aaggtgctgg taagcggaac cggactacgg aactgtttga aatgattgtt
     5101 ttgggatttg gagaccaggg cgggcggaat gatactcttg caagatttgt cggtgggtta
     5161 ctgagtcggt cggtggatcc agaatgtatc ctgcggcttg cggaaacggc caataataat
     5221 tctgttgaac ccttgggcaa aagagaaatg agacggacaa tcgaatcgat gatcaaaaaa
     5281 cacatgaggg ggggtggcca caataggtga aattgttaat atttcaatca agcagttttc
     5341 acgacgaaaa aagaaaatcc tgagcgaaga aggtgaacag attgaagtag aatccattgt
     5401 ggcagacagc cctagaaatg tcttactggc gatgaaaagc gataacaagt tgaatgattt
     5461 tctccggcac aatgaattca ccggtgaaca tgagattgtg gaggatgtaa aactggacgc
     5521 cattcagctt cgacgtgggc agcttccatc tacttttgag tcatatctga gcgtctattt
     5581 ggaaaatcat ttcaaaacag tttttaaggc tggagcttta agagatggca ttgaagcttt
     5641 ttttgcagaa aaaacctaca atcctgttca ggaatacatg gagcacgctt atgaatcttg
     5701 ggatcacagg gagcggttag ctcaagtttt ccaaacgtgg ctaggtgctg aagacagtat
     5761 ctttgttcag cgtattgcgg tcatgttctt tgtcggtgca gtttcaaagg tgtttaaccc
     5821 ctgggtcaaa tttgactata cattggactt agtcggtggc caaggagcag gtaagaccac
     5881 cttcctgcag aaagttgcag tcgaatggta cactgattcg gcaaaagatt ttatggataa
     5941 ggataattat gaaatcatgc tgaagtctct gatcgtcaac gatgatgaga tggtggccag
     6001 cagaaagacc acttttgatg agctcaaggc atttgtaacc aaaactgaac tgtcgtttcg
     6061 taggtcttac ggtcgcagag ctgaaaaatt ccctaaaaac tttgtgattg ctaggacatc
     6121 gaacaaggtt gagtacctag gagacaaaac tggtgagcga cgctttctgc cagtgctggt
     6181 ggatgcagac cagcagttgg tcaaaccgtt tgatatgact gatcgggatg tgctccaact
     6241 ttggggtgag gcggtcgcta tttacaaaaa agggtttacg cttacttttg atgatgactt
     6301 cgaagacgaa ctggcggtct ataaggagcg gttcacttat aaagatgaag cggaatcaca
     6361 gatttacgat tatctggaca tgttagttcc tgatgagtgg gaagaaatgt cagtggttca
     6421 gcaacatcaa tatacctggg catactttaa taatggcagt tatcgtaatg agtcgggatt
     6481 tgtctatgaa ggtgttaaac tgcaagcgag tgtttccgcc aagcagattt tgaaaaacgt
     6541 atttgatatc gacagtgcaa gaggtgagag aattgctcgc aaaatcaagt tgattatgga
     6601 caatcatcaa gattgggaat accgaataaa gaagataaaa gggagaactg tcagggcata
     6661 ttttaagaaa aatatgcaaa atgaagtgat gtaacctttt aggctaaaaa aggctaaaaa
     6721 agcttaaaaa tggcgtttgg gttacatcag gttacatcat tgatgtaacc tgccgaaaat
     6781 ccattaataa caagggttta gggctatttt ttgagaaaaa ttcaaaaaaa gtgatgtaac
     6841 ctatctaaag ccttgatatg actggtttta tgaggtgtct attagtatgg ttacatcatt
     6901 tatataaaaa ctttaataag taaaaatagc aagtgctata aacgttgata ttatgggatt
     6961 cttgtttttt ataaatatat tttttgaaaa gtgatgtaac cttgtaacct cactaaaata
     7021 tgcaaaataa tgaataaaaa ggagagtaaa tgagttataa agttttagtt tattttgaca
     7081 atatgttgga cgaagaatat aagtttaaaa cagaaaaaga tgcatcgaaa tgccatgatc
     7141 aattgcgaag gaaataccaa ggtcagcgtt tatataaggt aaaaatggag gaggtggaag
     7201 aagaggtaat cataactaac ttcagggagg ttgatcatga ctaaagacga ctttttaaca
     7261 ggttttgtac ttatactttt agctgcttgc atttttgctg tgggatttgc gattgggcat
     7321 gattatagca gtgagcacta cgagcaaaaa atcacagatt tacaaataca gctggtaagc
     7381 acgcagcagc agcttaagca atctcgtgag caaaatcaga gccagactaa aaggattgcg
     7441 aatctgaccg ggaatggagg ataaaaaaca ctacatggaa ataaaatgtg gaaattgctt
     7501 agaattacta acagagttaa ctgatggatc aattgatatg gtgataacag acccgccata
     7561 taacatatca gtaaaaaata actttgctac aatggggcgg acaggtatag attttggtga
     7621 ttgggataaa ggtgcggact tattaagttg gattgatatt gcaagtcgaa aattaactaa
     7681 aaatggtgga atggtgatct ttaatgattg gaaaaattta ggagatattg caagacattg
     7741 cgaaaaaaca ggcttagcag taaaagatat tttccgttgg gtaaaagata accctatgcc
     7801 aagaaatcga gataggagat acattacaga tagcgagtac gggatatggg tcgtccgaaa
     7861 aaattccaag tgggtattta atcgtaaatc ggaaaaatat gataggccag aatatcgcta
     7921 tcctattgta tcaggagcag agaaaacaca gcaccctact caaaagccgg tagccctgat
     7981 gagggacatc attacgcgac acacaacaaa aagggctgtt gttttagacc cttttatggg
     8041 cagcggatca actggagtag cttgtctact gacggagaga gactttattg gatatgagct
     8101 aaataaagat tactttaata tcgcaaacaa aaggattgct gagttgactg ggaatggtgg
     8161 atgagatgtt aagagtattt gaagcttttg caggtattgg tacgcaacgc atggcattgc
     8221 gaaacctcgg gataccacac gaagtagtag ctattgccga gatcgacaaa tttgccatta
     8281 aaagttatga ggcaattcat ggcccagtaa ataatctagg tgatattagc aagattaatc
     8341 ctgacactat tcctgatcac gacttattta cttatagctt tccttgtcaa gacatttctg
     8401 tggcagggaa gcaagctggt cttgatattg atagcggtac acgctcagga ttgctctggg
     8461 aatgccaaaa agttatagtg gctaaaaaac cgaaatatct attaatggaa aatgtaaaaa
     8521 atctcgtagg caaaaagcat aagccaaatt ttgataaatg gcttgattgg ctagagagtc
     8581 aaggctacac gaatgactgg caagtgctaa atgcaaagga ttacggtgtc ccgcaaaata
     8641 gagagcgtgt gttttgtgtg tcgattttag gtgagcataa accttatatt ttcccagaaa
     8701 aacaggaatt gaccatcaga ctaaaggaca ttttggaaga tgatgttgat gaaaagtatt
     8761 atttaacaac aaacaaagca aatgaattat tggccacgat tgtccgagaa aatgatgttt
     8821 ctgaaagagt tgttgtagat agtacgataa aaaaaccaaa aataaaaaat gtaatgaacg
     8881 ctgtaatagg aagatatgat gcaggcatcc gaaatcaaca atcggttgga ggtgctgtca
     8941 ttgagcttat tgaataaaaa tgcaacaaaa aaaggctact tagtagccga tgatggggac
     9001 ggaatagata ctgcttatcc agatagcaaa acgaggaaag ggagagtgca aaaaaacatg
     9061 agccatacga taacgacaga tgatagtaag gcctttttga ttggcgcaag tcgtgggaga
     9121 gaccccgaaa acccaaacga taggtcagct ggaaaccaaa acctacaaca aagacttgaa
     9181 atcaacaaaa atggcacaag caatacaatt acaagtgtcc aaaaagataa ctatgcggtt
     9241 gaattcccag attaccgcat ccgcaagcta acaccgctag aatgttggcg gttgatgggg
     9301 tgtagtgatg aggattttga aaaagcacag tctgtcaata gcaatagtca gctttacaaa
     9361 caggcaggaa acgcaattgt ggttgatgtg ctagaggcaa tattaaagca attattttta
     9421 accgaggcgc aaaatgaaca ttgaagaagc gaagcaaaaa ttacataaca tggcatatag
     9481 agatttacaa actaagccgt atgatttgaa acttgctgat gttattcaga ttcttaatca
     9541 aattaaactc gacaaacctc aaccagaaat tccacagttt gtcgctgact acatagatga
     9601 tatgcacaaa aacgcacgta cattgagata cgcttttaaa tacatggaaa gtaacataaa
     9661 aatgcacaaa tggtgtgttt tcgaaaagca agaaacgttt gttaatgctt ttttatacgg
     9721 atatacaatt gaaaaagaga aactgtacac tgttgagata ccaaatccga aaaacggtat
     9781 tgcgcatagg cacataatgc tggttaagac aactgacgga agagtagttt tgtctgaagt
     9841 agtagactca cacatacatt tgagagatga tttaagactc accgagtcag aaatccgcaa
     9901 agacttcgat tgggcttgga gagaggagtt tcctaaagag gtgacggaat gatgaatgaa
     9961 agagaattaa ataaattgat gaattacgac aaaaagaaaa gtgatttaaa aaaacgcctg
    10021 attataggat ttaccctatt gccaatcagc atcgtattgt ctggatttgt tattaaatac
    10081 ggttggaata atattttgtc aacaattgat ggcgtcccac ctatcaattt accacaagcg
    10141 atagcaattg atgtgctagt aagttttatc attgccaaga caaacgcaga aggagatttt
    10201 gccacagaag ttggcagagc ttttatttcg ccgttaatga cgttgttatt gttttgggta
    10261 gtgactttgt ttatgtaatg tttagaggta acagatgact gaagaattag gagtgttgct
    10321 tgacaaggaa ggagttgaat acgtaaaaat ggtatttgat gatggctttg tctggacgat
    10381 acgcaaccca ctaaacgctg cgttgcttaa acgccaagat gcagagcagt tcccgcagtt
    10441 tacgtgggtg ccactgacag atttataacc ccacgcaatg gctctgtggg attacgtgcc
    10501 aggaaccacg ttgaaagcga cttagacacc ttcattttta tcagccttgc ggattgtcaa
    10561 aggttcgtaa ggtgtagacc gaaattaaac acagaaggat gtgatgacaa tctccttaca
    10621 cccaaaaaat ctaacgctgg ttaccggtca ccagctatta tccaaggcgc taatactgac
    10681 atcgtgcgcc tgtgtcaaaa taaaaaaagg aagagagggc ttttctccac aaaaaaagac
    10741 gtccatgcga acgcctcctt ggttatatct gttaacacca ttataccaca ctgagggggc
    10801 ttttatgacg ttttttcccg agattgatat ccaaaaaaca aaatccaatg ccaagcgtaa
    10861 attgaaagag tatccacgct ggcggcggat agctaacgat gtagatactc aaaaagttac
    10921 agctacttac tcatttgagc caaggcaacc tcatggagtc cctagcaagc ctgttgagag
    10981 actagcactt aatcgtgtat cagcggaaca ggaactggat gcgattgaga gagcggtcaa
    11041 cgggatattt gatccagagt atagattgat actgattgac aagtatttgc tcacatatcc
    11101 aaagactgat tgtgatattt atacaaaact tggttacgag aaaagtcagt actacaacat
    11161 gctagataat gctttaatgt ctttttctga actatacaaa gaggggatgt tgcttgtcga
    11221 aaaaatggaa aaaagctgga attaatatgg aataattatg tactttatat ataaatattc
    11281 atgttattat agtactatga aataacaaga agagataacc attttaccaa ctgactattt
    11341 atttagtcgc tgactttaac tacgatcaaa cttgttattt tatgtatgtg ggacgtgcgg
    11401 gttcgaatcc tgccgtctca atcagcgccc agaagaggcg cgaccccata cccctttaaa
    11461 ggcagacacg ttctgatgtg tgggttttta tgattaaccg caagttcaaa aacaagggtc
    11521 gcaaccttgc ttgtggttag tagggacaac ggttgtaagt cggttcgatt ccgactgttc
    11581 ctgtgctagt catcacatcg tgatggcttt ttattatgca aaaaagaacc actaagtggc
    11641 tcttatgctt gtagttttaa ttcaagtgcc tctgtgagga cttgcgagaa attgagattt
    11701 tcatcttcgg ctgctttgtt taaccactca gggatagtca cgttcttacg tactttttta
    11761 gagtggtatt ttttcatgta ggcaatcata tcgatgccga ttaaagcaat atcagaatca
    11821 cgatactgtt cttttaagtc ggaaacggag ctagcctttg gatagtcagt atagtcttca
    11881 agagcaaagc ctaagacttc gacagccatt tcgtaagctt cttgaaagtc tttaccttga
    11941 gtaattgctt caggtacatc tggaaatgta accatgatat agtctgtgtc ttgtgtgaat
    12001 gtagctggat agattaacat aatgattctc cttcgatcac tgtgagataa gcaaaccatc
    12061 tggcaagcgg attattttaa acccgcctgc tttagaatgg tatcttcaag gccttttccg
    12121 aggtctttgt tgtgtagagg aacaatggtt tgatgtccgt tattatctcg gaattttttg
    12181 tgacttccgt tttgactgac ttcatagaac ccattctttt ttagcagttt tatcatctgc
    12241 tttggggtca ttggcatatt gcttacctca ctttctatac ttatattata cacgcaataa
    12301 acatggttgt caataggtat gcgcaaaaaa tgcgtatttt tgttttctat tttttattat
    12361 ggaggttagg gtatgaggcc gcagaagtta acaattgcgg gtggcagacg aacgactgtt
    12421 gactacgatg ataggtcagc tgagtatcgt gactataatc gtaacagatg gaagtatgat
    12481 aggaagacta agcagtttta taactctaag atttggagag agacaagtaa gcaagtctta
    12541 ttgcaaagtg attatatctg tgcaatgtgt ggtggagaag caacgatgac tgatcacatt
    12601 gtctcagtta agaaagattg gaataaaaga ttagattgga ataacttgca agcaagttgt
    12661 aaagcttgta acgattgtaa agcaataaga gagagacgga aaacctaaac gtacataaaa
    12721 agtaacatac gcaatcattg ttcgggaaat accccgccta ttttttaacg gggctatatt
    12781 gttcggaaac ttaagaacgc gcccttttct gtgcaaaaaa atcccttttt gaaatttttg
    12841 aaactgtaaa gtttgtgtaa aggaggtctt atgggaagaa atttaaagct agttgaaacg
    12901 acaaaaaagc atcttacgaa agaagaaaaa atagtgcgag aaaccgcgca aaataaggcg
    12961 tctgacggtc ttaaaaagtt gcaaaagaca cctcctgaac actttaataa tgtagctaag
    13021 tacgagtata ggagaatcat agaagacctc caaaacctac ccctaagaaa tctcgataga
    13081 gggctattag agttatattg cacatggtat gctatctaca aagaaacaag tagaaaacta
    13141 gatgaggttg gttattttac gaatgatcca gacaaaggca ttattcctag tccgcttatt
    13201 ttaacattgg aaaaagccac tgcgaatatt agaagtagtg ccagtcaatt aggactaacg
    13261 gtagatagtc gcatgaagat gtttattccg aaggaagaag aaaaacctaa gagtatattt
    13321 gataaatttg gaggatagag agaaaggggg tcatgacaat agaatacgat tattcagcaa
    13381 tcggcgacat ctataaagat gacgcttttt attatgcaaa aaaggtcgtt gatgaagaga
    13441 ttaaagcaag taagaaggtc tttaaagctt gtctaagaca tttgaatgac cttaaaaaaa
    13501 tagatgatga taattttaaa tttatctatt taccaaaaaa agcaattgac cccataattt
    13561 ttattgagct attgccagac gttaagacgg gaaagcctta tcctttagcg atgtttcaga
    13621 agtttattat cgggaattta tacggatggc gaaagaaaac agatcattcc ttaagacgct
    13681 ttagaaaagc tatgatttcg gttgctcgta aaaatggcaa aacaattctg atagctggta
    13741 tcttgcttta tgaatttttg tttgggcata atccatctat gagtagacaa ttgttttgta
    13801 cagctaatga ccgtacacag gctaaaattg cttgggacat ggcaaagaag caactctcat
    13861 ctttaagagc aaaggacgct gatgtcagaa aagccacgaa aattgttcgt gatgagctga
    13921 aaaacttaca tgatgaatct tatattaggg ctcttagtcg agatactggg gcagtcgatg
    13981 ggttcgagcc ttacgttggc gttttagatg agtttgcggc atcaaagaca aacgaaatgt
    14041 tagagctttt agaatccggt caaggtcagc ttgataatcc gtttatcttg attatctcaa
    14101 cagctggtat ggatttgaat gtccccatgc acacaattga gtatccgtac atcactaaaa
    14161 ttttagacga agaaattgta gatgatggct attttggata tgtcgcagag caagacaacg
    14221 aaggtgaaat taaagatgaa tcaaattgga taaaatcaaa tccaatcctc gaggttgaag
    14281 ctttgcacga taagctaatg gattacctga gaacgcgtcg tagagtgtct cttgaaacag
    14341 gtgaaattaa caaggtactt atcaaaaact ttaacatgtg gcggcagtcg agtgaggaat
    14401 catatattga taagcaatct tgggaacttg ctcgtattga taaacccgac acacataaac
    14461 gaagggtctg gctaggtgtg gacgtcggtc gtgttagtga cttatttgct attacaccag
    14521 ttattatgat ggacgatttt tggtatattg acagtttttc ttttgttgcg acaaagtatg
    14581 ggttaacggc taaagaaaag cgtgatggtg tgtcttacag taatttagaa cgtcaaggct
    14641 attgcgagat aacaacatta gaaagtgggg ttattgatga tgagagagtt ttagaaaaaa
    14701 tagaggagat ggtctattcg aatgactggg aagttaacgg aatctgtttt gacccttacc
    14761 aatttggaac gctgcttacg atgattgaga aaaggcaccc agaatggcct ctcatagagg
    14821 tttcgcaaac gacaatggtt ttgaacatgc caacaaagca atttcgtgat gatctcaaga
    14881 atggcaaaat aaagcactct ggcaatccat tgctaacaat ggctgttaat aacgcttata
    14941 tcaagactga taacaatggc atgaggattg ataagaataa gaatagcaat aagatagacc
    15001 ctctggacgc tgctttagac gggtatgcag tttgttactt agagccattt gacggctctg
    15061 gttactggac aagtgagaaa attttaggag gagagacact gttttgattg gttttatttt
    15121 aaaaaacata catacattaa tcttgttagc tggactaggt ttattgatgt atgggttgtt
    15181 tttgtttggt gataaagttg gttttatcgc tagtggtctt attttaattt ttttagctat
    15241 ctatgtagat agcgtaggag gaaaacatga ataaacgcat taagaaaaaa cgtaaattgg
    15301 aaacagcggt tgtgatgctt gttgcagaaa atgctatgca agctgaagca ctcaggaatc
    15361 aaaacagaca aattgcagag ctgagatcga ttatacaaca aaacgcccaa gcgacaaata
    15421 gagagtttgc agcagttaaa tcagcgacgc tagacaacca agcagccatt aagaaaattg
    15481 gggatgaggt ttattatatc aagcaaaatt ataagcgcaa gtggcggaaa tagatgttaa
    15541 tggtttagaa aggaggtgag aaatcgatga gtttttttca acctttgggc agttcaaagg
    15601 tgtcctatga tgactatgta tcatctgttt tagctggcga tgtctcccaa aaatacttag
    15661 gagtgtcggc tttgaagaat agcgatattt taacagcaac gtctattata gctggggata
    15721 ttgctaggtt tccgcttgtt aaaaaggatg ttaatgggga cattatccat gatgaggata
    15781 ttaattatct tttaaatgtt aaatccacaa aaaatgcgag cgctaggacc tggaagtttg
    15841 ctatggcagt aaatgccatt ttgactggta attctttttc gcgtattttg agagatccaa
    15901 agactaacca agctttgcaa ttccaatttt acaggccgtc agaaacgact gttgaggaga
    15961 cagataacca cgagatagtt tatacgttta ctgatatgtt gacagcaaaa caggttaaat
    16021 gttttgccca tgacgttatc cactggaagt tttttagtca cgatacaatt ttgggaaggt
    16081 ccccgctact gtctttaggt gatgagattg atttgcaaac cggcggcatc aataccttaa
    16141 ttaaattctt caaagatggt ttttctagtg gcatcttaaa aatgaaaggt gctcatataa
    16201 gcggtgaagc acgtaagaga gccagagttg aatttgaaaa aatgcgcgag ggtgcaattg
    16261 gtggtagtcc tttagtattc gatgatacgc aagaatacac gccgcttgaa atcgatacta
    16321 acgtattgca attaattaca agtaacaatt tttcaacggc gcaaatcgca aaagctttgc
    16381 gggttcccag ctacaagctt ggtgttaata gtccaaatca atctgttgcc cagttgatgg
    16441 aagattatgt cacgaatgat ttgccatttt attttgatgc tatcacaagt gagttaggac
    16501 ttaagacgct aagtgataag gataggcgtt tgtatcgtat cgagtttgat acacgaagcg
    16561 tcacaggtcg caatgttgat gagattgtca aattggttaa taaccaaatc ttgacgccta
    16621 accaaggcct cgtagagctt ggtaagcaaa aatcaacaga tccaaacatg gataggtacc
    16681 agtctagtct aaactacgtc tttttagaca aaaaagaaga atatcaagac aaggttggta
    16741 tcaaagggaa aggaggtgag gtaaatgcca aagaggataa atcttaaagg accactaatt
    16801 gcaaataact ctcaagaagt ttacgactat tacggaatgg aagcagcaag tgctaaaagt
    16861 atcattgagc aatttcctga agataatagc gatattgttt tggaagttaa ttcaaacggt
    16921 ggacttgtga cagttgggag tgaaatctat accgctttac gaaattacaa aggaaaagta
    16981 actgcagaaa ttactggcat ggctgcaagt gcagcatctg tggctgttat gggtgcggat
    17041 aaggttgtca tgagtcctac agctcaaatg atggtgcata aagcactctt taaatgggtg
    17101 tctggtaata gtgatgacct agacaaagct tctaatgcct taaaatcaag tgataaagct
    17161 attgtgagtg cctatgtcgc aaaaacaggg ttatcagaag atgcaatcat ggatttaatg
    17221 cgaaatgaaa cgtttatgtc cgctcaagat gccgtagaaa aaggttttgc ggacgaagtt
    17281 atgtcttttg aagcagttgc tagcattgat aattccatgt tgccgcaagc tgttattgat
    17341 gactattaca gaagtaggaa caaacgaaaa caagagatta gcaacatgtt actagaaatt
    17401 gaaaaagaag aaattttacg agggctataa gctctttttt tattggagga atttatgttc
    17461 gaagaaaaaa tcaaagaaat taaagcgaat atcgctaatt taaaccaagc tattgctact
    17521 aaaacaacag aagtaaaaaa tgctttggaa tcagatgacc ttgaaactgc tcgctcaatt
    17581 aaagcagaaa ttgaagaagc taaagcaaac ctagcagaag cagaaaatga cttgaaattg
    17641 tatgaagcta gcattgaaaa aggcggtgca gaaaatactg gaggaaaaga agtgccacaa
    17701 gaaactaaaa cataccgcga aagcgttaac gaatttattc gttcaaaagg aacagtaact
    17761 aatgaagctt tgcgttttga aggaaaagat gaagttctta ttccgcttaa tcagacaaca
    17821 ccagtcgctc ctgacacaga tggaattaaa aagacagacg tgaaacctgt ttctagcgaa
    17881 gaaattctat acacaccagc tcgtgaagtt aagacagttg ttgatttgaa acaatttact
    17941 agcatccacc cagctaagaa agcatctggt aaatggccgg tattgcaacg tgctacagaa
    18001 aaaatggtaa gcgttgaaga attggaaaaa aatccaaaac taggcaaacc acaatttaaa
    18061 aacgtggagt gggaagttaa aacttatcgt ggagctatcc cgttatccca agagtcaatt
    18121 gatgatgcag atgtagattt ggttggtatt gttgctgaaa caatcggtca aatgaaagtt
    18181 aatacaacta atgatgcaat tgctaaagtc ctaaaaacat ttgaggctaa agctggtgtc
    18241 aaaacattag atgacatcaa aaaaatccta aatgtagatt tagatccagc ttacaatgtg
    18301 tcatttattg tatctcaaag cttttaccag tccatggata ctttaaaaga cgaaaatggc
    18361 cgttacctac ttcaagattc aatcacttct gcgtctggca aagtgtttct tggaaaaccg
    18421 gtatttgtcc tatctgatga cgtaattggt aaagactcag cttttgtcgg agattttaag
    18481 cgcggcgtgt tatttgctga tcgtaaagat ttagggcttc gttgggcaga taacgaaatt
    18541 tacggtcaat acttgcaagc tgtccttcgc tttggtgtcg ctaaggtaga tgacaaagct
    18601 ggatactatg tgacattcaa accagaacaa ttgccctcat aaggccactg aagaagtggc
    18661 gaaaccaact agcaaaagca ctgtcgagga gattaagcgc tatttaacaa gcaagggaat
    18721 tgactttaat gggaaaacat taaaatctga tttattaaaa cttgcaggcg ttgaagaggt
    18781 atagctatgg ctgtatcaaa agagttatta gacagtgtaa aactctattg taaaattgac
    18841 tttgattttg atgacgacat catcaaagaa atgattgaat ctgctcaaga acaaatctgt
    18901 tttgcaatag aagacggttc tactcctgaa aagttcaaag gtcacgctaa atttaattta
    18961 gctgtcaaaa agcaagtcaa ggaagagtat gaccatcgcg gtttgtctgc ggatagtttt
    19021 cgctatccgt tggcaaatgg tgttttaaac attatccatc aattgcgatt gagaggtgat
    19081 gattcgtgat tacacgcaag atgaacgtca ggataacgat ttttagccaa tcaggcgggc
    19141 aaaatgaaga tggtgaagta gtatctgctg tcagaaagga cttgtatact tgttgggcag
    19201 aagtgctaaa aacgcagttg agagatttta attatcaatc aaagtatcaa aacgctagca
    19261 atttgccaac aaataaggat actaaggttt ttttaattag gtataaccct gaattatcta
    19321 tagataacac gatgtttgtt gagtttggca agcgcattta taagatagat aaaatcgaat
    19381 ctgacgaatc tggcaaagat attatcatga taagtggagt aagcatgtca tgacaaaagg
    19441 tttagatgaa atattggcta atctgacaaa gcttgaagta aaagcaccaa aaaccgcaaa
    19501 agcagcagta actgaagttg ccaaagaatt tgaaaaagca cttaaagcaa atacccctgt
    19561 ttatgagatt gaaacagatg agcggctaca ggaagatacc gttatcagtg gttttaaagg
    19621 agctaatgtt ggaattgtat ccaaggaaat tggctatggc aaagcgactg gttggcgtgc
    19681 gcactatcct aacgatggga ccatttacca acgcggacaa gactttaagg aaaaaaccat
    19741 caatcagatg acaccaaaag ctaaacaaat ctacgcagca aaagttaagg agggactagg
    19801 actttgattg ctgaaacagc agcttataaa ttattaagta acgataagac gctaaatgag
    19861 ttgttggata ggctcagagg cggtcctttt aaaaatgggt ttaagcaagg catatttact
    19921 tatgatattc cagataaccc agttgacttg cgtaaggtag atttagcgcc ttttatgcga
    19981 atcaacacaa cattagacgg tcctgctgat tatgcagatg atgagatact gtgtaacgag
    20041 caacggatca ccatcaattt ttggtgcaaa acagcttctg aagctgacca aattagcaaa
    20101 tgtatagatg atattttaaa aaaaggcggt tttgaaagat acaccgcaaa cgaaaaacca
    20161 agatataaag atagcgatat tgacttactg ataaatgtaa ggaaataccg ctattttgat
    20221 ttttattaaa agaaagagga aaaaatggga aaagtaaaat ttggactacg tgacttccaa
    20281 tacgcagtac tcggagatga tgatcaatta aaaacaaaaa cgggaggtat caaatcacta
    20341 cctggcatga aatcagcaaa gcttgatatt acaaacgaat tagtgacggt agctgctgat
    20401 gatggtccat acgtagtttt atctggaggt attacagaaa caaaacttga aatcgaggtg
    20461 ttagacttaa catctgacgc acgaaaagac ttcttcggaa ttaaggaaga agacggaatc
    20521 gaaaaataca ataaggagct gacccctaac gatgttgctt gtatgttccg aacaagcgat
    20581 gaaaacggga aagccatctg gattggattg ctaaaaggta agtttaacat tccgggtatg
    20641 gaaatgcaga ctaaagaggg agcgccagac cctaaatctg atactgtaac aggcaacttt
    20701 gtgtctcgtg gaaaagaagg agatgttatt gttatcggtc gcgaaagtgc tagtggtttt
    20761 aaattagaga agtttaaaga atttgtgttt gctggtgcga cagatattaa aaaaggcgaa
    20821 aacttcgaaa tgtaacaatc aggttggatt taaaatccaa ccttttattt ttgataagga
    20881 gtagatatgt acgaaattac cttaaaaaaa ggtggtgtag ataaagtttt ttcaaaggac
    20941 tttattaacg ttgaggataa tttgttggct gttgagcatc aagttagaca aagcgctgtg
    21001 tttagcgatg agaaaagacg cttagattct aaagcgcata gaaaacttaa cgaatcttac
    21061 ttgcaaatgt ttgttgatat gtacgcaggt caatttacag tcgatgattt aaagcaatct
    21121 gacatgagtg ttttaaatac acttaatgac ctgtacattg cagcactcgg tggagagcaa
    21181 gaggaagacg aaagcgaaaa aaaggaacaa taaccccaca agaggctaaa gaaaacttac
    21241 tcttgtggat acagagcctt ttgaaaaacg gttataccat tttagatatt aaaaaaatgc
    21301 gcttatctga tattgaattg atggtacaag cgctagaaat tgaaactgtc gaaaaagaag
    21361 aagtgattga aacgaccttg gataaggcat tcccattcct tttcggctag aaaggaggat
    21421 aaatggggaa tataggtgat ttagtagcaa cggctacact agacatatca ccatttatgt
    21481 caaacacaag aaacctaaaa acctacatga aaggcttaga taactcgtta aaagcagttg
    21541 aaaagagctt tcaagggcat ggcgggcgga tcaaaggtct taaagcggtc tatgctgaaa
    21601 caggtagtgc attaaaaggt taccaagaat tactaaaaac tcagtcgcaa aaatatagcg
    21661 acctaaaaaa agagataggt gatgttaata acgctactgc tgagcaaaag caaaaattga
    21721 ttggcgctaa atcagccatg ttggagactg ctgcgaaagt cacagaattg caaaacagat
    21781 tacgatcgtt agccactgaa actagcgttt ttacaagatt tggtaaagct gctgaaagaa
    21841 tcggcgggaa gatgaagtca ttcggcgatt cggtagctgg agttgatgct gcatttacaa
    21901 gaggagtcac cgctccgatt gtagcgggcg ctggttatgc tattaaagca gctgttgact
    21961 atgaaactgc atttgctggt gttaaaaaga cagttgatga gacggcgaca gtatcttatg
    22021 cgaagctatc acagggtatt agacaaatgg ccaaagagtt gccagccagt gctgttgaaa
    22081 tcgctcatgt cgcggaggcg gcaggtcaat taggagttaa gacaggagat attcttagtt
    22141 tctctcgtac aatgatttat ttaggagagt ccaccaattt atcggcagaa gaagcggcga
    22201 cgtctattgc taaaattgca aacattacag gtctggcttc atcggagtat tctcgctttg
    22261 gtagtgctgt tgtcgcgttg ggtaataact tcgcaacaac tgaaagagac atcgtagcga
    22321 tgactaatcg cattgctgcg tctggtaagc ttgcgggatt aaccaatcaa gagatgttag
    22381 ctttagcaac agcaatgtca agcgttggta tagaggcaga agctggtggt acagcaatga
    22441 ctcaatcatt gtcagctatt gaacgtgcag ttgcatctgg aggagataat ttaaataaat
    22501 ttgctcaaat tgccaatatg tcatctgctg atttcgcgag agcatggaaa gagaagccaa
    22561 ttgttgcatt gcaagagttt attaaggggc ttggccagct tgataaaaaa ggtgaaagtg
    22621 ctacaaaagt gcttgacgac ctcggattaa gcggtatccg ccagtctaac atgttgaaat
    22681 ctttaggatt agcatctgag actttaggca aggctctaga tacctcaaac aaagcttggc
    22741 aagaaaacac tgctttaact gacgaagcta ataaacgcta tgagacaaca gagtctaagc
    22801 taaaaatgct taagaatgaa gttaatgatg tagctattga atttggtggc cctttggttg
    22861 acgctctaag aaatgggctc gaagcaggaa aaccaattat tcaaatggca gcagatttag
    22921 ctaagcaatt taactcgctt gacaaagagc aacaacaaca aattgttaag tgggggctta
    22981 ttgcagccgc agctggtcca gctttatcta tctttggtaa aggcgttggc attatcggag
    23041 gaaccattca agctatgggc aaaatgagtc gagggttagg cactttatca ggctggttga
    23101 ggacattcag aactggagca gtagcagcta gtgcaggagc cgaagctgcc acagcttcta
    23161 tgggcggaat ggctggcgcg gttgccttat taagtaatcc tgtaacttgg ggtgtgctgt
    23221 taggtggtgc agccattgtg ggtataggtt taattgctga tagcatgtat aaagcccaaa
    23281 aacgcacaga agagtgggga attaaagtga gtcaagtgca agccaatgaa ttgcaaagat
    23341 ttaaaaacaa agttgacgaa gctaacctcg caatgacaac atttggagtc aggagtgcta
    23401 ataatctcga taaaatcaag acatctttta aagcactggc agacgaaata gaggctttac
    23461 aaaacaaaaa acttaagaag gatctaaaac tagccgaaaa gttaggtctt agtcaagaga
    23521 caatcgagga gattaggcgt caagctgacc aaactgtggc aacagttaga ggtatgtctg
    23581 acaaagttgt agacatttac cgaagagcca aagaagaaag aagaagtttg actgaagaag
    23641 aaaagactgt tgtcactaaa aatttgaatg acatgatcca gactgagtta tctttgatga
    23701 actactctaa aaaagaaaag atcgccattt tgaaggcgat gaatggagag attgaaacgc
    23761 ttaattatga gcaacttaaa aaagctcaag aagttgctca aaagatgata gagagcgaaa
    23821 acaagactta taaaaagaga cgaagtaatc tcaaagaaat gtatgacaat atcaaaggag
    23881 actctgaaac tgctgtgaga gccagagagg agattcacag acagctggag accttggaag
    23941 atagtcatac agcaaaaatg gagagtttag gagaaagata cttaaaaatt cgtaaaaaac
    24001 ttctggaaga cccagcttta gatccacgag ttaagcaggc tatgattgat agcttagaca
    24061 aggaatttga aaaattagga ttatctttcg aaaagttatc taaaaggagt gaagaggcta
    24121 gctctaagac caaaataagc atgcaagaca tgacaagctc attcagagca tcgataggcg
    24181 aagccattag ttcattgcaa gggtgggaca atcttacgcc gcaggaaaaa caattgttga
    24241 tagatgggaa taaggctgtc agtgagatcc taaatagtaa aactttactt gagcaatggc
    24301 aagcgctgac ccctcagcaa aaagaactgt tagctaaaaa tctaactcaa gacccaacgt
    24361 tatcagctca acaagcaatc gataatgtta agcagcgagt gccagctgat gttaaagcct
    24421 cggacaagac tgctccagat gtcgcttctg ccgatagagc cgttaacagg cctaagcaaa
    24481 aaggtccagc tattattaga gcacaggata atgctagtag tgttgctagt ggagttattg
    24541 ggtggctaaa tagtatacct cgtacagtga catcgacaat aactacaatt gttcgtaaaa
    24601 taaccggcca taagacggga actgattacc accctggcgg tttagcgatg gttaatgacc
    24661 aaaaaggtcc tttgtatagg gaattgatca ctttaccgac gggagaatcc tttatcccgg
    24721 aaggaagaaa tgtcattctt cctttgccaa gggggtcaaa agttcttaga gcaagtcgta
    24781 caaaacaatt attctcgcat tatgcaaacg gaataggttt taatgatacc aaaatcgcta
    24841 gcttaacaac tcgtcttaaa tctgtgcaag ataaaggaca agtgattgtc aataccgatc
    24901 ctcaacttgc ggagttgatt aaactactta aagatagaga taacagaaat gtcacaaaca
    24961 actacacact taacgctaca aacaggagta actctgatga tatgtttaat caagaaaaca
    25021 tgagacgtct cctaagagaa cttgcatact atacaaatgg agagaaaggg aggttggctt
    25081 aatgcgatac attgaattta atggtaagaa aagtgatagc tttggtcttt tgctagagcg
    25141 tgaacgatct attaagtcaa cgagtaacga tgttgattta atagaagtcg atggacgcga
    25201 cggtgtactc ttaaaagaca atggtcgttt gaaagctatt gagcaagact ttcctttttc
    25261 tttggttggt gacgtggctg tcaatcagca aaaaataagt gaatggttac atgtcaaggg
    25321 ttggcacgac ttagctttgt cttgggacaa ggactatatc tatcgggcta gtgttgtcaa
    25381 tctttttgaa atagacgaga tacttaagca atttggtaga ttaaaggtta atttcttaat
    25441 ccaccctatc aaatacctaa aaactggtaa gcaagaggtg tctctcgtta atggtggcac
    25501 tctacaaaac cttggtaatg tgcagtctaa acctatctta aaaatcaaag ggacaggcaa
    25561 cggtgtttta accattaatg gttttgagac gggcctcgaa aacgtccaag gagagctcat
    25621 catagatatg gagaggcacc ttgtctataa agatatcctg tctgcttggg ataacattgt
    25681 gcggacagaa cgccaccgca tgccactatt tgatattggt caaaacaaaa tctcatggac
    25741 tggtaacttt actatcaccg cagtgccaaa ctggggggtt aaagtatgat accagtttta
    25801 tacgaggcca aagaaaccaa atttaggact tttggccttg gtgagatcgc agacgcttat
    25861 gaggtaagag ttactcgtga gcgcaacggt aattactcgc tatatatcaa atatccactt
    25921 gatggtgttt ttgcctcggt ctttaaggag gagcttaaga ttaagtctga tgccggccga
    25981 aggacaaaat ggcaaacttt tgagatcaat cgggtgttgc gaaacagtaa agaccacatc
    26041 gagatttttg caaggcatat ctcaatgcgc acacaggaca tcgctttaaa accatttgtg
    26101 agcgggtcta gcattgacgc agagtcggca ctggaggttt ggcgggataa tcttgtcggt
    26161 gatgatacct ttgatgttaa aagcgacatt ttaacactag gcagctttaa ctgggaagtt
    26221 gacaagatag gcaatgcaag aggcgctctc gggggtgttg ctggctctat cttagatgtt
    26281 tacggtggtg agtacgagtt tgacaatcgc acaatcatct tacataaaca aatggggcgt
    26341 aaggccccta cggttttgga gtatggccgc aatatcgtca gcgtggaaga ggagcgtttg
    26401 cttgatggca attatacctc aatctatcct tacgtaagat atacgccaca accaaagccg
    26461 caagaggaag cctctggtaa gccgcacatc ggtgagcagg agcagcccga agaacaactg
    26521 gtgacgctgc ctgaatttat cctagatggt cagtatcttg acttatatgc ccaacgcaga
    26581 atacagatgg ttgatttatc tagtcatttt aatgatgaca aaaaagagcc gacagtcgaa
    26641 gaaatcagaa agctggctca gaaatatctt aaagataaca atgttggcgc acctaaaatc
    26701 agtatagagg ttgattatat cgacctgtca cagacgcttg actatcaaga ttttagagtt
    26761 atggaggagg tcgagctttg cgatattgta ccgctttact atccaaagtt tggtatcaca
    26821 accgagaccg aaaaagtcgt tgagattgtc tatgacgtct atacagatag caatcacaca
    26881 ataaagcttg gcacgattgg ccaatctatc tctaagagtc tgacaggtgg tgttacgcag
    26941 cggattgaga cgctggaaaa caaccaaaag gttattacta ataatcaaca gcaatttgag
    27001 cttaatttac ccaaatacct caacgatcta aacggtacca agatatggta cgaaaaacca
    27061 gatgacaacg ttgagcacaa gataggcgat ttttggtttg agaaaaacgg taaatatcag
    27121 cgtacctggg tttgggacgg gaatcaatgg gtaaaaatca ttgatactga ggatttaaat
    27181 cctaatcagc gagcttttga tgaggctatg gccgagattg aaaagctaaa gcagcaccag
    27241 cgagaactcg acgaacgcaa ccaaaaagag ctcgaagagt ttagagaaac cctcaaaaat
    27301 ctgtcgctgc ccgaggaagc catcaaaaag ataacagagg ctatcaaagt tgatgatata
    27361 ccgtcaatta aacagtcgtt tgacgacctc aaaaacaaag tcagtgagac gagcgagacc
    27421 gcacgattaa acgctgagat tatcgggaca gatggcaaga cccgctacaa caaaaactta
    27481 ttggttggcg accctaatcg tgtcaaaaaa attgatgagg attttatcga ggtagaagcc
    27541 aacgatggtg gctttagacg cggtgagact tacaccatca gctttagcca aacttgcgag
    27601 ctgctcaaaa aagtggctat cacgttgacg caagctaata ataagggtgt taaattagtg
    27661 ttgataccga ctaaagctaa gatggaggcg cagaccttta atctaagtaa agataaggag
    27721 gtcatcagcg tctatccttt gagctacagg gctgttttga caggtgactg gtataaatct
    27781 aagcagattg agttaaatgc ggcagaggtc caaaatttgg ctctggagat gtcttataga
    27841 gacgtagttg atagcaataa tgctagtttg attttggatt ggtccccaaa tccagatgtt
    27901 atttttgatg gaaatggagg tagttaatgt cagagactat atcagctata gttgtgcata
    27961 aaagcatgac aaaaaacgag tgggagtcta gtgacatcat tttgccacaa ggccagctcg
    28021 tctatgagtc tgacacaggc catagtaaat ttggcgacgg taaaaataga tatgcagatt
    28081 tgatctatca aggtgggcca cctggaccac aaggtccaca aggactaagt ggcgaccgcg
    28141 gtcccatagg acaaacgggt ccacaaggta aacaaggtgt cagtgtccaa agtgcatcag
    28201 tagatagtga gggctattta actgttttgt tagataacgg acagtccttt aaatctgata
    28261 gcagcttaaa aggatctaaa ggagatactg gtcctaaagg tgctgacggt aaaatgactt
    28321 ttgagcaatt gacgccagag caaaagcaac aactaaaagg cgacaaaggt gatccaggtc
    28381 ctaaagggga cattggtcct agaggcgcaa cggggcccca aggtcctaaa ggagagccag
    28441 ggataaatgg tatggacggt ccaagaggtg caacaggtcc ccgaggactg caaggcccac
    28501 taggaaaaga tgcggttttg cccgacgacg ttgttagacg tggtgagcta gcagcttatc
    28561 tgctacggtc ggaatacaaa gctaaaggct caggatcagg tctaagctat aaagttgtca
    28621 cccagtctga gtacgatgat ctgtatgatt acaacgacaa cgagttgatc ctcgtgacgg
    28681 agggttgaca tggcatataa gctttatact aaggctgatg ttggtgacaa catgttgctt
    28741 gtcgctggcc gccctctgcc cgatgacaca aagcgcctaa aaatccagcg tgagacgtta
    28801 gatgtgttaa ctattaccca ttatggctct tacgacatgg tgcacctcaa gtcgacagtc
    28861 aaaaaggcgt atagcaaaaa tacagttgtt actcctgtat ctgcagctgc tagcaagccc
    28921 aaagctaagc caaagcacgt tttaaacttt gctaaggcta ataaggttta tataggcagc
    28981 actcgtgtaa tagcagtgta tttgggtgat cgcctgattt ggtctgacaa acatagcagc
    29041 gggaccaaaa ctgtctcggt tgtggggagt cttgatatca gacaatcaca aaaaatgctg
    29101 tatttgtact taatagcgcc agacgtcgca gatgttaaaa gcaagcgcat taaatcgata
    29161 gcgatcaatg gcgttaaact gtcaagcact gcacaaatca gctttgaggg cagcagctat
    29221 tattaccttg tgacaatcaa gcaagttgct aacatcaaag agatcaaaaa tatagcgtca
    29281 aaaaacaaaa tcacgctaga gttttaggag gtaacaattg agcagagacc caacaataac
    29341 attagacgag tcaaacctcg tcataggaca agatggccgc atgcactaca cgtttgtagc
    29401 gcaagatgat aaccaaaaag tcagactggc tagtaactgt ctaggcacag cgcattttaa
    29461 ccagctgatg attgagcgag gaggccaagc gacggactac gttgcgcccg ttgttgttga
    29521 gggcagcggc aagccaacgg gcttatttaa agatcttaaa gagcttagtc ttgagctcac
    29581 agatactgct aattcccagt tgtggtcaaa aatcaagctg acgacaaacg gcatgttacg
    29641 tgagtatcat cgtgatcata ttaaaacaga aattattgag agcgccgatg gtattgccaa
    29701 gcggattgcc gatgacactg gccaaaagct ggcactaatc aatgagacca tcaacggtat
    29761 cagacgcgag taccaagacg cagatagaca gctatccgcg agctaccaag caggcattga
    29821 tggcctaaaa actcaactgg ccaatgataa aatcggtcta caagctgaga ttaagctgtc
    29881 agctcaaggc ttgtcacaaa aatacgatga ccagatacgg cagctatact ctaaaatcac
    29941 cacaacctca tcaggtacca cagaggccta cgaaaacaag cttgagggct tgcgggcaga
    30001 gtttacaaga tctaaccaag gcctgcgcac tgagttagag tcgcagatta gcgggttaag
    30061 gtctgtgcag cagtcaactg ccagccaaat ctcacaagag atcaaggacc ggacaggcgc
    30121 tgtcagtcgg gtgcaacagg acttaaatag ctatcaacgt cgattagcaa gtgctgaggg
    30181 caattacagc agtcttttgc agacagttaa aggtctacaa tcaactgtta gcgatcccaa
    30241 aggtaaaatc caatcacaat ttacacagct gcaaggtcaa attgagcatc gtgtgactag
    30301 agatggggtt atgagtatca tcaacgagtc aggcgatagc attaagctag cgatccaaaa
    30361 ggctggtggg attgacgcta agatgagcgc taaagagatt atctcagcga ttaatcttaa
    30421 cggctatggc gtgcggatct ctggcgagcg tattgctctg gacggtaata cgaccgtcaa
    30481 tggggcattt ggggctaagc tcggtgagtt tattaagctc aaagctgatc aaatcattgg
    30541 tggtacgatt gacgc
//
LOCUS       DARYLD010000023        29896 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYLD010000023 DARYLD010000000
VERSION     DARYLD010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29896
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            336..662
                     /locus_tag="TU651_000898"
     CDS             336..662
                     /locus_tag="TU651_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL0896910.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
     gene            649..1074
                     /locus_tag="TU651_000899"
     CDS             649..1074
                     /locus_tag="TU651_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896911.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            1093..2148
                     /locus_tag="TU651_000900"
     CDS             1093..2148
                     /locus_tag="TU651_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL0896912.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(2252..4534)
                     /locus_tag="TU651_000901"
     CDS             complement(2252..4534)
                     /locus_tag="TU651_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL0896913.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            4666..5199
                     /locus_tag="TU651_000902"
     CDS             4666..5199
                     /locus_tag="TU651_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0896914.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU651_000903"
     CDS             complement(5406..6017)
                     /gene="rpsD"
                     /locus_tag="TU651_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL0896915.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(6541..6813)
                     /locus_tag="TU651_000904"
     CDS             complement(6541..6813)
                     /locus_tag="TU651_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL0896916.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU651_000905"
     CDS             complement(6830..8206)
                     /gene="dnaB"
                     /locus_tag="TU651_000905"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL0896917.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU651_000906"
     CDS             complement(8227..8679)
                     /gene="rplI"
                     /locus_tag="TU651_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL0896918.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            complement(8676..10652)
                     /locus_tag="TU651_000907"
     CDS             complement(8676..10652)
                     /locus_tag="TU651_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL0896919.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU651_000908"
     CDS             complement(10740..12638)
                     /gene="mnmG"
                     /locus_tag="TU651_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL0896920.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            complement(12641..13105)
                     /locus_tag="TU651_000909"
     CDS             complement(12641..13105)
                     /locus_tag="TU651_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0896921.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU651_000910"
     CDS             complement(13310..14434)
                     /gene="mnmA"
                     /locus_tag="TU651_000910"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL0896922.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU651_000911"
     CDS             14715..15386
                     /gene="sdaAB"
                     /locus_tag="TU651_000911"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL0896923.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU651_000912"
     CDS             15398..16270
                     /gene="sdaAA"
                     /locus_tag="TU651_000912"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL0896924.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            16304..16939
                     /locus_tag="TU651_000913"
     CDS             16304..16939
                     /locus_tag="TU651_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL0896925.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(17000..17611)
                     /locus_tag="TU651_000914"
     CDS             complement(17000..17611)
                     /locus_tag="TU651_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL0896926.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(17867..18676)
                     /locus_tag="TU651_000915"
     CDS             complement(17867..18676)
                     /locus_tag="TU651_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0896927.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(18669..19511)
                     /locus_tag="TU651_000916"
     CDS             complement(18669..19511)
                     /locus_tag="TU651_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0896928.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(19487..20326)
                     /locus_tag="TU651_000917"
     CDS             complement(19487..20326)
                     /locus_tag="TU651_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL0896929.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU651_000918"
     CDS             complement(20329..20871)
                     /gene="pgsA"
                     /locus_tag="TU651_000918"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL0896930.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(20884..21888)
                     /locus_tag="TU651_000919"
     CDS             complement(20884..21888)
                     /locus_tag="TU651_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0896931.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(21938..23221)
                     /locus_tag="TU651_000920"
     CDS             complement(21938..23221)
                     /locus_tag="TU651_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0896932.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(23223..24467)
                     /locus_tag="TU651_000921"
     CDS             complement(23223..24467)
                     /locus_tag="TU651_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL0896933.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            24682..25095
                     /gene="yaaA"
                     /locus_tag="TU651_000922"
     CDS             24682..25095
                     /gene="yaaA"
                     /locus_tag="TU651_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL0896934.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            25097..26206
                     /gene="recF"
                     /locus_tag="TU651_000923"
     CDS             25097..26206
                     /gene="recF"
                     /locus_tag="TU651_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL0896935.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(26271..27134)
                     /locus_tag="TU651_000924"
     CDS             complement(26271..27134)
                     /locus_tag="TU651_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL0896936.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(27305..29734)
                     /locus_tag="TU651_000925"
     CDS             complement(27305..29734)
                     /locus_tag="TU651_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL0896937.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            complement(29737..>29896)
                     /locus_tag="TU651_000926"
     CDS             complement(29737..>29896)
                     /locus_tag="TU651_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL0896938.1"
                     /translation="INPMGGFSIHLIINDDPDTYLRVRLSRYDLERNLEIASNYRSEK
                     LEKLLKGE"
BASE COUNT         9189 a         6531 c         5479 g         8697 t
ORIGIN      
        1 tgagagatat gttggcttct gatttcatat aagacctgcc atcgcccttc ctgccaaatc
       61 aaaggtaagc aaaccgcata acatcgctcc tcacccaagg gcctagcctg ataatgttca
      121 ataatgctct tcatctgtcc ttctccttat catatccatc actaagctac tttcatagta
      181 taaaatagta atcctttggt caagaaatgg ctccgattac tctctatgat atataaaatt
      241 tttatatata aaatattgac atattaaaac agaaactcta tacttaatat ataaaataat
      301 tatatataaa tacgaggcag gaagggagta accagatgta ttttccagta tctgctacct
      361 tgattgaatt tttgatttta tctattgtcg acaagcatga ttcctatggt tatgatatca
      421 gccaaaccat taagcttgtc gctaatatca gggaatcaac cctataccct attttaaaaa
      481 agctagagaa atcagactat ttaactacct atagtcagga acatcaaggt cgcaagcgta
      541 actattacac cattacagcc aaaggcgaaa agcagctgat tttcttaaag gaagaatggc
      601 aaagctacaa ggccacccta gatggcatta ttgaagggag attaaggcat gacaagagat
      661 gaatacctag cagagctaga caaataccta cgaaaattac ctaaagcaga ttattatgaa
      721 gctgctgaga actcaagtca gctagaactt aacgacggca gtatcaaaga ctcttctatc
      781 actgtagctg atacaaaaga agaaaacgac tatgactata cagacccctc cgagcttgct
      841 ataaatcatg tcacaatcaa ggagaaaaac acaattaatg gcggcgatat taatatcaat
      901 accacattag caaatccaag agatattgct tatcatgtca caacaagagg caacatcaag
      961 ctcagctctc gtttttcaaa cgccaagctt aacacagacg cagcaacagg agctacttca
     1021 tttcactctg acatagccaa tactgtcaat caaagcgacc tatcaattca ttaatcaagg
     1081 gaggatatca taatgactaa acaagatttt ctagacaagc taaagcagca gatcaaccat
     1141 ttacctcaaa aggattacca agaaatcatt gaccatttta cagagtattt tgacgaggct
     1201 ggtcctgacc atgaacaagc tattcttaaa gaactgggaa atccagagga cattgccaag
     1261 gagctattaa aagccttaga tctccccgaa aaaacagacg aagatgactg gacgaattgg
     1321 gaagttgaca acaaaacaaa gtcagaagca agctcacaaa agcttgagcc aatagttgac
     1381 attcgctata gtctgcttaa ccatgattta accattgaaa ctgctgacat tccttaccct
     1441 actatttcat acgatgataa tcgcatcaca ataagccaag atagtgacgg catgctcaat
     1501 atcattgaag actcagcagt acaaacaata cagtatggct ttcatttcct agaccgctgg
     1561 cttgcaaaat atcaacccat taccttgaca ctacctgtca accaccacct gaaaaaaatc
     1621 tctggagaaa gtgacaacaa cgatgtcacc ataaggcata tacattgtga tagcattgtc
     1681 tctaacactt acaatggaac gatttctatc agtcatttat cagatagcac tgtcaaccta
     1741 agcagcaaaa atgggaacat tattttagag cattgcaata tccagtctag taaatgtcaa
     1801 gccaaaaatg ctaacctcag ctgtgacaat agcaccctaa taaattgcca gctgaacaat
     1861 aacaatggaa acatcagatt agaagcaagt cagctaacag aaaccttcat tgaaaacaaa
     1921 aacggtaata tcatagggca gcagctgtcc ttttccaatg acatcactat catcaataag
     1981 aatggaatca ttgacatcaa ttgtcctaga gaaaacctca tctactatga cgtaaaggct
     2041 tcaaataata atggatttgt aacgattagt caagaagcag gtcgtcaaac accctttaaa
     2101 gcacagctta ccatttccaa taataatggt cttatctccg taagctaaac caaccataaa
     2161 aaaagcttct agaaagagct taaaccacaa tttctagaag cttttttatt atatctactg
     2221 tttaacgata acctgttatc tcagctatta tctaggacga ttgcttgtcc tttggacgat
     2281 aaatcagcac tcctatagcc ataaagctta acaaaaagcc aactaataca ctcgtctcta
     2341 aacctatctg ggcagttaat gatattgtct gacgaaggcc agagacaata taagacattg
     2401 gaagataagg atggagaatc tggaagatct gaccactcaa ctcaatagga taagaaccac
     2461 ccgcagcacc aacctgtagc aacagcataa ttaacgaagc aaaggcacca tatcgagcat
     2521 cccagctgac caatgcagtc actaaagcca tcaaggccca tccactcagc ataataaagc
     2581 ctaaggtctt gataccgtca ttagcttcaa agcccagcag ttgaagtgca gcgtaaagaa
     2641 taacagagcc aacggtcgaa atcatgccat tgatcagtaa tttttgcttt gcccaatccc
     2701 atctatcttt aatcggctta ccagataagg cctctgcaaa aataatattt gtagacaagg
     2761 caactaccat tagagacaca gcaatcatat aaggagccat gccaatacca ttggtcctaa
     2821 ccttatcctt gtccttctct gataacgcta ctggatcaga taccatatca gcattctggt
     2881 cctctaccca agccattgaa agctggtcag aagcttttga tagtgaggtc gttaagcttg
     2941 acagacctgt tgacagagtt gtcaagccat ctgtcaactg agagctgcca gaggagagct
     3001 gattggctcc aaaagctagc tgattagcgc ctactgtaag ctgctgtcca cctgctaata
     3061 attgactgga ttgatggtta agagctgttg cccctgtagc aagagtagac aggcctgctg
     3121 taagagcttc attcttagct gtcaattgat taaagccgcc agcaagagct tgactacctg
     3181 ataagagctg ggctgttgtc gctgagtgaa cagcccttaa accagttgaa agctctgaca
     3241 atgccttgcc tgtgctaggt aggatttgat cagcttgata agccagctga ttaacaagtg
     3301 ctttaaagtc cctcagttga tcagctacac cagcacttgt tgacatagcc tctagctcct
     3361 cagacatggc ttgcagtgat gtcaacatag cctttgctga tattgttact ttagttgaag
     3421 tattggaaat agctgagctc agctcctcct gctgctcaga gttgagacct tgataggtag
     3481 ctgtagcttg tagagcggct agctgattgt tcttgtcagc agtatcatct accacaagct
     3541 cctgcactaa acgcgtcata tcggctaaat gcttagcaat ggctcctgag tccacatttg
     3601 gtgccaaaga caaggaaaga ttggtcttta gctgctggat agcctgatta agctttggta
     3661 ggctagccat taaagcttga atattagctt gtttgtcttg agacagatca cttcctagag
     3721 ccaattgggt caagccagca tttaactgat tagcaccctt ggataaccga gaaacaccat
     3781 ctagatacgc tggcatatca gctgctagct gtcctaagcc cgcggtatca agctgaccaa
     3841 caccggctgt ataggcagct ataccactag atagattacc cgctccttga gacaagcgag
     3901 cacttgattc agacaaggtg ttcaaatgcc ttgacattag ctgactgctt gccctagcaa
     3961 ttactaagcc agcggctaat tgctgaccgc catttgaagc ttcctttaga ccagattgga
     4021 gctgatgcat gctcttaaaa acggaggtga tataggtctt ccttatattt ttagaaacag
     4081 cctctctcaa gtgattcata gcagattcac ccattttaga agcgataaag ctatggccct
     4141 tactagtttg atagctaaca atcagcttct ctggctgctg atctaatagc gtagtggcct
     4201 tttgtgacaa atcctttggc aacgtaatcg tcatataata acgacccttt tccaagccct
     4261 tttgtgcggt atctgcagcc acaaaatgat aatccaattc cttattttta gacatattgt
     4321 ctaccatatc gttaccaata gtcagtctct tgttattcaa gtaagcaggc ttatcctgat
     4381 tcacaactgc tacaggcaac tgatcaaccc gaccataagg atcccacatg gaccctaaaa
     4441 aggacaaatt atagagagct ggtactagag caaccccaat cattgtcact actagcttac
     4501 gatttttgat tattgctttt aatccttcta gcattatttt ttctccaaat agacatactg
     4561 ttcaaaaatt atgataaaat atattataca aataaagtga cattttacaa ggaaaaaata
     4621 aattttttag acataatgtc tacaagtgtt caaaaggaga taatgatgga tagccgcaag
     4681 cagcaaacca agaaggccat tcttaatgca atggtgagct tactaaaaac cgaaagcttc
     4741 gatgatgtaa caaccgttca gcttgctaaa atggcaggca ttagtcgttc tagcttttat
     4801 actcactata aagacaaata tgagatgatt gattactatc aacaaacctt ttttcacaaa
     4861 ttagaataca tttttgaaaa agaataccaa aacaaggagc atgctttttt agaagtattt
     4921 gaatttctca agcgagagca actactatct gctctgctat cctccaatgg tacccgagaa
     4981 atccaaagct ttatcattaa caaggttcgt ctgttgatca ctaccgatct tcaggacaag
     5041 ttcagtaagg acatcttgtc cccaaccgaa aaggaatatc gaagcatcta cctagcacat
     5101 gcctttttcg gtgtctgcca aagctggatt gctaaaggaa aaaaagaatc ccctcaggaa
     5161 atgactcgtt tcgtcttaaa aatgctatct aaaacatagt cctgcactaa tgatgtcaaa
     5221 tccagtacca aaaaacaact ttgtaaacta tttcttactg agtttataat gatctttatg
     5281 cctaacaata ccgacctcca atcgttagac ttttggtcta acctttgggg tcggtacata
     5341 aatcagctaa ccgctcaacc aaaaaagccc actgttgtgg gcttcttata atataaagtc
     5401 ttatcttaaa gcattttgtt gtagaattca acgacaagtg cttcattgat ttctgggtta
     5461 atttcgtcgc gctctgggag gcgagttaat gatccttcaa gcttttcagc gtcaaatgaa
     5521 acaaaagctg gacgtccaag agttgcttca actgcctcaa ggattgcagg aaccttcatt
     5581 gatttttcac gaacagagat gacttggcca atctcaacgc ggaatgatgg gatatcaaca
     5641 cgcttaccat caacaagaat atgaccatgg ttaacaaact gacgtgcttg acgacgagta
     5701 gttgcaagac ctaagcggta aaccacattg tcaagacgac gctctaaaag aagcatgaag
     5761 ttgaaaccaa gagttccttc tttgattttt gtagcttgta cgaataggtt acggaattgt
     5821 ttttccccca taccatatga aaagcgaagc ttttgcttct cagcaagttg caagccatat
     5881 tctgaaagct tgctacggtt gttagggcca tgctgaccag gtacgtagtt acgacgtgcc
     5941 aattccttac ctgtgcctgt caatgacaag ccaagacgac gtgattgttt ccatgatgga
     6001 ccagtataac gtgacatgta tcatgtcctc ctctaaaaaa tataacgagg aaataactgt
     6061 ttgaaaaatc ctgattcgtg caggaggttt tcgcctaaac agcaaaggtt actcaattta
     6121 gttaaccgcc tgttgacgag cttcatattt ttctgctgtt atttcacaca aaactaattg
     6181 taacatgaaa aaggtattga ttcaagtttt ttttacattt ttaatatcat atcatcaaaa
     6241 atggttagct gtaagctcaa agatgatgtt aatcatatgg caaacaagct tttacacaac
     6301 acttcccgag taaacaaggc tttttaatac cgataggaaa ttctttgaaa atagcatatt
     6361 atgttttgat atctaatacc gagagtctca gagtaactgc ttttcaagaa agctagtccc
     6421 tattattagt ccgggcttca ttcatttgct aataagttct tcaaggcttc aaattgattc
     6481 atatctttac acagctgtca acaaagtgta aagaaaaagc cctaaatggg cattgatttt
     6541 tcaatcaaaa taacgaatca gtgttttttc cgtcaaaata tctgaatagg tataagactc
     6601 aacataagaa ttattcgctt cccctgaagc atctgggttc ccctgatact caatgataaa
     6661 taaagaaggg taaacctcta tcaatctgcc aaccttattt ttttcacgct tacgaccatt
     6721 ttcaagtgtt aactcaacca actgaccttc atgagcctta atgtcttcct ttattttttt
     6781 cattttggca acatctgtaa atgcatcact cattctcttt ccctctttct tatctttcct
     6841 caaattgagc tattgtcgaa aatttattgt attccttttg aaacatcagc ttaactgtcc
     6901 cacgcgcacc tgccctattt ttctcaagaa tcacctcaat tgtattatcc tcaagagcct
     6961 cttctgtgct gtcgctttct ttacgataat aatcatctcg gtacaaaaat gcaacaatat
     7021 ccgcatcctg ctcgatagag ccagactcac gaatatcaga caaaactgga cgcttgtcct
     7081 gcctctgctc aacaccacga gaaagctgac tcaaagcaat aacaggcact tttaattcct
     7141 tagctaaaat ctttagctgc cttgaaatat cagaaacctc ttgctgacga ttttcaggtc
     7201 ttgtaccagt gatcagttgg aggtaatcaa tgacaattag ccctaagcct ccctcaacct
     7261 cctgagacaa tttacgtgcc cttgctctga tctcagtaat cttaatgcca ggtgtatcat
     7321 caatatagat aggtgcttct gccaaggctc cttgggcaat ggtcacatta ttccagtcct
     7381 gatcagtcaa ctgaccagtc ctcaagctat gtgaattgac cattccctca gcggccagca
     7441 tacgatcaac aaggctttca gctcccattt ctaaggagaa aatggcaact gctctctttt
     7501 gctttgtacc aacattttga gcaatgttta agacaaaggc tgtcttaccg actgcaggac
     7561 gagctgctaa aataatcagt tgatctgggt gtaaacctgt tgtaatcttg tcaagatccc
     7621 taaagcccgt tggtaaacct gtaacgtctg atgtctgctt agaacgaacc tcaagatttt
     7681 cataattaat ctttaaaacg tctgagatct tacgaaagcc actgcgattg ctatgctcac
     7741 tgatatcaac caaggccttc tcagcacttg caataatatc ctccgagtca gatgctcctt
     7801 cataggctaa gtttacagtc tctgtcaacc tattgatgat atcgcgtagc atagcctttt
     7861 cagctactat tttagcatag tattctgcat tggcactggt aggtacacta ttaaccagct
     7921 caacaatata agacaagcca ccaatatgtt gaaggtcccc ttgatcatca agaatcgtcc
     7981 ttaccgttgt tgcatcaata gcatcatttc gatcactaag ccttatcatt gccctgaaaa
     8041 tgaccttatg agaatactta taaaaatcct ctggaccgat aaattctcta acggtaatca
     8101 acttgtctgg ggaaataaag atagagccta gtacagactg ctctgccaat aaatcttggg
     8161 gttgaactcg taactcagca acttcaggca aactcagcac ctccaaatct tttttaggct
     8221 gatgtgctat gcctcagcaa tgtttagttt tatttcagct gtcacttctt tatgcagctt
     8281 aactggcact tcgataagac caatagcacg aatagggtga tctaaaacaa tatgacgctt
     8341 gtcaaccttg accttaaatt gcttttgcaa ttcctcggaa attttcttag ctgtaattga
     8401 gccaaaggta cgcccatctg gtccaacctt ttccttaaac tggacacgag ttttttcgtc
     8461 atctaagatt ttcttaacag ccttagcctc tgctaggatt tcagcctggg ctttttcctc
     8521 agctttttgc tgccctctta gctggccaat tgcttgactg ctagcttcct ttgctaaatt
     8581 tttcttaatc agaaaattct gagcataacc agtgggaacc tccttgattt ctcctttttt
     8641 tccttttcct ttaacgtcaa ctaaaaaaat gactttcatg actctacctc tcttgtttct
     8701 ttcattgtgt tatcaattgt ttctagtaac agctgcttag cctcgctaag actgatatgc
     8761 ttcatctgac acgctgctaa gttgaaatgt cctccgccgc caagcttttc catcattctt
     8821 tggacattga tcttactacg acttcttgct gatatagcaa tcttatcagc tcctgtctct
     8881 acaataacaa agctagcctc aatatgggcc attgatagta tggtatctgc tgccttacta
     8941 gcaatgacat tactataata ttgcccagca agcccagttg caacgataat ggagtcgcta
     9001 aggcgctcac ctctgagaat gatctcatta acctgcttat agtcatcaaa atcagttgct
     9061 gaaatatttt gaatttcgac gctatcacta cctctgcttc gtaaataact ggcaacatca
     9121 aaggttctac tggtgacacg tgttgaaaaa ttcttagtat ccagcataat accagccatc
     9181 aaaacacttg cttgaatctt gtttaagcgc ttcttcgcat tttgaaactg gattaattct
     9241 gtcactagct ctgcggcact gcttgcacca ctttcaataa aggtcaagat agcattatct
     9301 ggaaaatcat catctcttcg gtgatgatca acgacaataa catcttgaaa ttgctcgtaa
     9361 aattccttag acaaggttaa ggaaatctta gagtggtcca ccattactaa cagtgatcta
     9421 ggggtcgtaa gccccattgc ttgagaaata ctgataagac gtgtcttacc atcagcctgt
     9481 aagcgctcaa tagctctttc aatgtctgga ctcatctcat ccggattata gacagcaaag
     9541 ctgttttcaa taatgttact agcaaaaaat tgcatgccaa cagccgagcc taaggcgtcc
     9601 atgtccagtt tacggtgacc tacgataaac acattatcaa ccattttgat acggtctgaa
     9661 atagctgtca tcatggcacg cgtcctagtt ctagagcgtt taaccgtaga aacagagccg
     9721 ccaccaaaat agaccggatt tgtatggtct gcattttcac gaataacaat ctgatctccg
     9781 cctcggacaa gagcaatatt cagattctca agagcaacct gaccaatttg acaatgattt
     9841 tcctctccaa aggaaatgcc catacttagg gtcaatggta gctgcgcttc ttgggcttcc
     9901 tttcggaact gctctaaaat agaaaactta tcgtccatca gcccttttaa gatcttatag
     9961 tctgtaaaaa agtaaaaacg atccatatta acacgtcgat aaaatacctg cttagactcc
    10021 ataaactcag ctatgaaatt agccacaaat gaatttatct ttgacgtatc agcatcagat
    10081 aagtcatctg taatgtcgtc ataattatcc acagaaataa taccaataac tggctttagc
    10141 aagctagaat ctgctgattg tctactacca acagagctat caaaaaagta aaaaatacct
    10201 gatgccacat caatataaga cgtgtatcga ttgccagaaa cctcaaaggt ttgagaaata
    10261 tcacttttac gcttatcagt gagaagctgt tggatcatct gttcctgtaa aaaaccggcc
    10321 tcatcagtga aaatcagctc tgcgtaagga ttgtaccatt caatagcatt ggtttcttga
    10381 tcaaactgaa taacaccaac tggcatgtta tccagtaatg tttttaaatt attttctgtt
    10441 tgttcgttca atagctcaat gtggtctaaa tcagacaatt cgtaaacctt tttttgatac
    10501 caaagcaagg ccgcaacaaa caacaacact aaaaaaatag ctagtgtaat cagcattttt
    10561 gattgcatga ttctaacaca taaggctagt aagccgaata aaatcaactc catcataatt
    10621 aaatgaatgg tttcaaaacg aaatcttttc atctttaacc tcttaatccc gtattatacc
    10681 ataaaacagc cctgaaatac agagctgtca gtggttttga gattacaatt tgatgactat
    10741 tatgttttac ggcgagcctt tccattacct tcaaggtaaa ccattaaaat gctaatatct
    10801 gccggattta cacctgaaat gcgactagcc tgaccaatgg tttctggatt gattttctta
    10861 aatttttgcc ttgcctcagt agcaattgag tcaatagcgt cccaatcaat ggtcttagga
    10921 atccgctttt cctccatacg cttcatttta gcaacctgat caagggcctt tttgatatag
    10981 ccttcgtatt tgatctcagt ttctagtagc tcaatcagct tagcatctaa tccctcagca
    11041 gcaggaccta taaatgacac tacagtggca tagtcaacct ctggtcgacg cataaattcc
    11101 ttagctgtca ttgcgtccgt caaggactta aagccaagct tttgaacacg agcattggtt
    11161 tctttgattg gctttaattt gatactatct agcctcttta attcattgtc aaattgattt
    11221 ttcttgattt caaaggcaga ccaacgctca tcgtcaacca agccaatctg acgaccaatt
    11281 tcagtcaatc gcatgtccgc attatcatga cgaaggataa gacgatattc tgcgcgtgat
    11341 gtcagcaaac ggtaaggctc caaggttcct ttggttacca aatcatcaat cattacacca
    11401 atataagcgt cgctgcgctt taaaatgagc tcaggcttac cctgaacctt caaagcagca
    11461 ttgataccag cgacaaggcc ttgaccagca gcttcctcat agcctgaggt tccattggtt
    11521 tgcccagctg taaaaagccc tgaaatcatc tttgtttcaa gggtagcacg aagctgatga
    11581 ggtaatacaa tgtcatactc aatagcatag cctgttctca tcatctcagc attttcaagc
    11641 cccttaatag agtgaaccaa ttccttttgg acgtcctcag gaagacttgt ggatagacct
    11701 tgaacataga cctcctcagt gtcaaagcct tctggttcta aaaagagctg atgacgctct
    11761 ttatcagcaa atcgtacaat cttatcctca attgatggac aatagcgtgg gcccactccc
    11821 ttgacgactc ctgaaaacat aggtgctcga tataggtttt tagtgatgat atcatgacta
    11881 atctgattag tgtaggtcag ccagcaagga atctgattag ccaaataatc tttgtcctta
    11941 gacataaagg aaaaatgatt tggagtcaca tcaccaggct gaatctctgt cacctcataa
    12001 tcaatagaag aagccttgac acgtggtggg gttcctgtct taaagcggcc aatttcaaga
    12061 ccaagctttt tcaaattatc agctagtgtc actgaggcca agctgttatt cgggccagac
    12121 gaatatttca attctccaag gataatctca ccacgaagag ctgtacctgt tgttatgatc
    12181 actgcctgag ctgcatattt ttgccctgtt gctgtcagca ctccaacaac cctaccattt
    12241 tctactaaaa tatcatcaat catagactgg cgaagagtga ggttttcttg cttttcaaca
    12301 gtatgcttca tctcacgtgc atacaagctt ttatctgctt gagctcgtaa tgctcgaact
    12361 gccggtccct tacctgtatt gagcattttc atttggatat aggttttgtc aatgtttttc
    12421 cccatctctc caccaagagc atcaatttcg cgaacaacaa tacccttagc tgaccctcca
    12481 atagagggat tgcatggcat aaaagccagc atatcaagat ttatcgttgc taataaggtt
    12541 ttacacccca tacggctagc cgctaagctg gcttcaacac ctgcatgtcc tgctcctaca
    12601 acgatgacat cgtaggattc tgtaaattca tgtaccatat ctactccttt atctcaatat
    12661 gttttatatg ctgaggctgc ctgtcccaat gctttatagc cctttttaaa caactaggat
    12721 tgagccttat cttatctaga tcatcaagag caacccactc acaaacccta gtacaatcac
    12781 cctcaactac agaagggcta gaatcagata atagactcac aatataatga aactcaatct
    12841 gatgaaagtt cactccttct agacaaaatt gattttcaac cacaaaggct aactgagcaa
    12901 ctgaaacctc agctcctacc tcctctagaa cctcacgctt gacagcttct tctgtgcttt
    12961 ctccaacatg aatagcacca cctaaaagat aatagtcctc tttgggtgat ttggcaagat
    13021 aaatatagcc atccttaatt attaacgctg aagccctaac accaaagcta tggtctgcta
    13081 tccttgttct aaaatcctga accatctttt ctccttgaca ctgtttttaa gctataaaaa
    13141 tagtcaaaac ctgagaaagc tgtaagccaa aaagacttac aattcccatg agctttgacc
    13201 atcatcgtta ttgttaacct tattctatca aaatctgcca gcttgtcaag acttatcaga
    13261 tgacaaaacc gtcaacttta ttgacacatc tgtcaattaa catgtcaagc taaatatatt
    13321 gacaaggctc gccatcttta tacgccatat caataatacc accaccaaga cactcatgac
    13381 catcataaaa aacgactgct tgaccaggtg taatcgcacg ctgaggctca gcaaaaacaa
    13441 ccttagcttt gtctttcttg acatgaaccg tcaccttaga atctggctga cgatagcgga
    13501 actttgctgt gcattctaag gtgaattctt caggaacttc tcttgtaaac tgaatgacag
    13561 aagcgtcaag actagttgac attaaggact cgtggtaaaa gccttgacca acataaagga
    13621 tattttgtga aaggtctttt ccaacaacaa accaaggctt gttatctcca ccctgctgac
    13681 caccaatgcc aagtccccca cgttggccaa tagtataata catcaagcct gcatgctctc
    13741 ccatatcacg accatcaaca gtcatcatac gccccttttg agctggtaaa taatggctaa
    13801 gaaaggtctt aaaattcttc tcactaataa aacaaatccc tgttgagtct tttttctttg
    13861 ctgttgcaag gcctgcttgt tcagcaatag cacgtacctc tgatttttgc aggtgcccca
    13921 agggaaacat ggttttttgg agttgctctt gtgatagttg gcttaaaaaa taggtttgat
    13981 ccttaccctt atcaagacca cgcagcatat ggactacacc attctcatca cgtttgattt
    14041 gggcatagtg acctgttgcc acataatcag cacccaatgt catcgcataa tcaagaaagg
    14101 ctttaaactt tatctcctta ttgcacatga catcaggatt tggggtgcgt cctgaacggt
    14161 attctgctag gaaatactca aacactctat cccaatactc tttttcaaaa ttaacagaat
    14221 agtaaggaat accaatctga tcggctacgg ctgccacatc tttataatcc tcagtcgccg
    14281 tacaaacacc aaattcatct gtatcgtccc aattcttcat aaagacgcca atcacatcat
    14341 atccctgctc ctttaacagc aaggcagtta cagatgaatc aacaccgcca ctcatgccaa
    14401 caacaacacg tgttttcgag ttatctgtca tcatttattc tcccatcaat ataagataca
    14461 aggacatgag aaaaagaata gaacgaatca acttgcctaa acaagactct agcaaatggt
    14521 tcatttctat attttttgtc tttgtccaag tgttttctca aagctcgatt tgaaggtcga
    14581 tttgaagcgc cgctagacgc atgactatta taacagtatt gtctcttatt tccaacaata
    14641 tcttttttca taacaaacga catttgatta gcgatttgtt ataataaaaa ggataaaaag
    14701 agcatggagc atatatgaac acacaaaaat ttcaatcagt ttttgacatc attggaccag
    14761 tgatgattgg accatcgagc agtcataccg ctggtgctgt tagaatcgga aaggttgtcc
    14821 actccatttt tggagaaatt cctgatgagg tgacctttca tctatacaat tcatttgcta
    14881 agacctatca aggccatggt accgacaagg cactagtagc tggtattatg ggcatggata
    14941 cggataatcc aaacatcaag aattctcttg aaattgctca tcaaaagggc attaaaattt
    15001 attgggatat tttaaaggat agcaatgctc cccaccccaa tactgtaaag attagtgtca
    15061 aaaaggctga taaagcaatg agcattacag gtgtgtcaat tggaggagga aacattcagg
    15121 tcacagagct aaatggtttt tctgtttcct tgtctatgaa tactccaacc ttgattattg
    15181 tccatcaaga tatccccgga atgattgcta aggttacaga tatattgtca gctagtgata
    15241 ttaatatcgc tcaaatgact gtgactcgtg aaagtgcagg tgagaaagcc attatgatta
    15301 ttgaggttga ttctcgtgat tgtcaagttg ctgtcaagca gattgcaact attcctaatc
    15361 tgcataatgt caatttcttt gactagaaag gtatattatg ttttacacaa ttgaagagct
    15421 tgtcaagcag gctgatgata ggtttgatgg taatgtagca gagctgatga ttgctacaga
    15481 ggttgaaatg actggtcgaa gcagggcaga aatcctatcc atcatgtcac agcatttaca
    15541 ggtaatgaag gattctgttg tcagcggatt gacagcaacc aaatctatta gcggattgac
    15601 tggcggtgat gctcttaaga tggatcatta catcaaaaaa ggaaaggggc tttcagatca
    15661 aaccatttta acagctgtga gaaatgctat ggctgtcaat gagctaaatg caaaaatggg
    15721 acttgtttgt gcaaccccga ctgctggaag tgcaggctgt ctacctgctg tccttgctgt
    15781 tgctattgat aagctcaagc tatcagaaaa ggaacagctg gactttctct ttacagcagg
    15841 tgcctttggc ttagtcattg gaaataatgc ctctatctcc ggagcagaag gaggctgtca
    15901 agccgaggtg ggctctgcct ctgcaatgag tgctgcagcc cttgttaagg cagcaggtgg
    15961 taccgcttat caggctagcc aagcggtagc ctttgtgatc aaaaatctat tgggattggt
    16021 ttgtgatcct gttgctggct tagtcgaagt tccctgtgtt aagcgtaatg cattaggatc
    16081 aagctttgct cttgttgctg ctgatatggc attagcgaat attcagtcac aaattcctgt
    16141 agatgaggtt gttgatgcta tgtatcaggt tggtgccgca atgccaacag cctttaagga
    16201 gacagctgag ggaggattag cagcaacccc aacaggtaga cggtatagta aagaaatttt
    16261 cggagactaa tataatcaag taacgataga ctgaggagac gtcatgaaag caatcctatt
    16321 tgacttagat ggtactttgg tggattctag tataggaata ctaaatgcct ttgaatacac
    16381 ctttcaaaaa atgaaaatcc cttgtcctga tcatagcata ttatcgtctt acatcggacc
    16441 acccttagaa gcgacctttt cagcattttt taggaatcag catgatgtcg aggttgctat
    16501 aacacacttt agagattttt acagggaatt aggcatttac caagcaaggc tttattctgg
    16561 aatcacagag ctattagata atctctcgca agaaggtctt gacctctatg tgacaactag
    16621 taaatatgaa cctatggcaa ggcaaatgct tcaggattta acgattagcc attatttcaa
    16681 agctatccta ggctctattt ctaatcggtg tcacaagttg gatatcgtca aggcatgctt
    16741 acaagatttt gctattaata aaaaagaagc tataattgtt ggagatacca aatttgacat
    16801 gattggtggt aaacaagcag gcattacaag acttggagtt acttggggat ttggttgtca
    16861 agaggattta caagcacatg gcgcacaata cattggacac acaccccaag aggtgattga
    16921 gattatccag tcattgtaaa acgatactaa aaacctatca tcacacaaga tgataggttt
    16981 ttaacgctgt tatctgttct tagtagcccc aagctgataa gccctgtgca cgataggcat
    17041 ttaaggctga atttacctga tcctgaacgg ttgcagttga tccccagcct ggcatggttt
    17101 ggaataatcc tgaagcacct gaaggattag ctgcgttagg gtttccattt gactcacgag
    17161 cgataatggc ttcccaagta gcttgtggaa caccagtagc tgccgccatt tgagctgctg
    17221 cttcactacc gatagcccct gcggtattgc cgttagaaag gattactcca ttgctataag
    17281 ccactggtgt agctgcatac tgagcttgag gagcagcctc ttgcacagca ggactagcta
    17341 cctcagaagc tactgattcc tgagctggtg ctgcatcagc agaggaaggc tctgcctgct
    17401 cagctggctg ctccttggtt gcagcctttg ctactgttga tttttttgtt ttatgatgtt
    17461 tcttcacaac cttagtatca gaagctttag cataggaatc agtgtttaca ttttcacttg
    17521 aaaaagcaaa aactactgcg agcaaagcaa tagcagctgc tacaatgcca aaactaaaat
    17581 aacgttgttt caaaatgtct tgtttaaaca ttaaataaat acctcacttt tctctgttat
    17641 ccatattaac tgttaattat tacttgtcta tttaagatat attaaaaata ttacagcaat
    17701 attgatattc caagttttct agcctgatat cagtgttttt tgagcttaag aagctcaaaa
    17761 taaaaacaat gcctaagttc agacctgtgt aacagatgat ttaagcattg ttattattaa
    17821 taaattctag ttgctacagc ctaacaaagg ggctgctgta atatagctag gtgagccttg
    17881 agggactttt tagacagaaa aggaaaatcc ccaaaatgac taccaaaata atggctagag
    17941 tgtcttttaa ttgccagctt agcaggcggt attttgttcg actgtcaccg ccttgatagc
    18001 ctctagcctc catagcgatc gctaaagcgt cagctctttt aaagcttgaa gcaaaaagag
    18061 gaatcaaaat agggataatc gactttacct tttgaataag attgccttct ccaaaatcaa
    18121 cacctcgcgc tttttgcgca ttcataatac gagttgtatc gtccatcaag gttggaacaa
    18181 accgtaagct caaagataac atcaaaccga tctcatgggc aggtacctta aacctaacta
    18241 aaggcttcaa cagcgcttca acagcatcag ataagcttag tggggtggtg gttagggtta
    18301 acagcgtgga aaagaaaata atcaaaacaa atcgcatgaa aatcaaaatg gcttgactta
    18361 atcccaagct tgttatctta attattccaa gctgaaaaag aactgatcct ccctgtgtaa
    18421 aaaaaacttg aaaaagcgtt gtaaatagga taataccaat cataggctta acaccattga
    18481 aaaagaaaga ccattttatc tgtgacaaga aaatcagcag caaggtaaat gctaacagca
    18541 aaagattagt taccacatta ttggcccaaa aaataatgat aatatagata atcatagcaa
    18601 gcagcttgct tcttggatca agccgatgaa taattgaatt cccaggaata tagcgaccaa
    18661 gaatgagttt atccatgctt taatacctct cttaattcct ccaaagtaat gggtaaatag
    18721 ggtaaatcaa agccttgctt agccaggcgt tgggcaaagg ctgtcacctt agggacacct
    18781 aattgttttt cttttagcaa atcaatgtgt tgaaaaatag cctttggctg acctgataag
    18841 atgattttac cagcttcaag gacataaaca aaatcagcat aattagcaac atcgtccatc
    18901 agatgtgtca ccagtacaat ggtcatgcct gattgatgga gcgatttaaa aagactcatt
    18961 aattcctttc gccctttggg atcaagccca gcagtaggct catctaacac caaaatatcc
    19021 ggctgcatcg caagaatacc cgcaatagca accctgcgca tctgcccacc agaaagctca
    19081 aatggatttt taccaaatag ttcctctgaa atccctacta gggttaattt ttcacgcgct
    19141 aaagcttccg cctctttctg agaaacacca aaattttgtg gtccaaaggc aacatccttc
    19201 aaaaccgttt cctcaaaaag ctggctctca ggaaattgaa agactagacc aacctgctta
    19261 cgaataggct taatatcttt attttttgac tgactagtta tctccttgcc tgctaccgta
    19321 accttgccgg tggtcggcag atgcaagcca tttaagagct gcataatcgt tgacttgcct
    19381 gagccagtat gaccaataaa agccgtataa gagccgtcta caatatcaag attaacgtca
    19441 aaaagggcac gcccctcaaa gggtgtccct gcttgatacg tgtagcttac attttggaaa
    19501 tgaattgaca tagctgttcc tctaattcct tttctgtgag atagattccc tgtatagggt
    19561 agccgtcttt ttttagcata ttaacaacag aggttgtaaa aggaatatct aaacctagat
    19621 tgatcaattg attgccccta gcaaatagct cctgtggagt cgagacagac tcaacacgcc
    19681 cattgttcat caccaaagct cgatcactaa gagccacctc atcaagatca tgtgtaatag
    19741 atataacagt tagttggtat tcttgtctaa tagattgaat tgtccgaatc aactccagac
    19801 gcccctttgg atccagcata ctggttgctt catctaaaat gatgatcatt ggccgcatgg
    19861 caacagcacc tgcaatagca acccgctgct tttgaccacc tgataatctg gaaggctcct
    19921 tatccttaaa agcctccata ccgaccagct gcaacgcctg atgaacacgc tctatcatct
    19981 cctgatggga aacacctttg ttttcaagac caaaagcaac gtcatcttcg acagttgcac
    20041 caacaaattg gttatcagga ttttgaaata ccatgccaat tttatgacga atgtcccaga
    20101 cattgtcctc tgtaagaaga tcaccatcaa caaaaatctg gccggcttct gctttcaata
    20161 gcccatcaat taacctaaca acggttgact tgcctgagcc attatgccca atgatagaca
    20221 accactcgcc ttgtttcaca tgaaacgtca catcatctag ggtatatcgc tcctggtcct
    20281 gcttatactt aaatgtaaga ttcttaactt caataatatt tgacattgtt atttaaaggt
    20341 atccttaaaa agaaagcttg ctcctttgaa ataatcgtaa cctgaataaa tcgtaaacaa
    20401 tagagcaata tacagcaaaa cagtgcctaa aacagtccaa tgacacagta aaaagatgat
    20461 ggaaagcatc tgtgctactg ttttgatctt accaggcata gcagctgcta ggaccttatc
    20521 tccagtctca accaatagca aacgaagtcc tgtaacagct agctcacgac agataataac
    20581 cgctgacacc caagccggta ccagctctaa gcccactaac ataataaaag cactcatgac
    20641 aagcatcttg tctgccaatg gatcagcaaa tttaccaaaa ttagtaacaa cctgccactt
    20701 acgtgcaagg taaccatcta aataatcggt caggcttgcc actgcaaaaa taatcgctgc
    20761 aaaggtatgc caaccgactg tctttgaaaa agaggtgatc aacaaaaaca atggaatcat
    20821 gacgatacgg gcgagagtta acaaattggg aatattttct tttttgatca tgcttatacc
    20881 ttattattgt atcttcagtg tgatatagct gatatcagta cttgtcattg ctgataaatc
    20941 taggggctga ccatcaattg ctactgaaac accctttgtt acgcctagtg tcaacaagga
    21001 ttctgttgtc tcagcaggca aggtagtaga ataagtcgga ttgtcctttg ttagggtcat
    21061 accagcctca ccaatttccg aattagtgag ggaaatccaa ctgctctcag catcagtcag
    21121 tgacactgta acatcaacag cttcttttga tttagtaata ttagcaatca agtaattctc
    21181 tgcgccctct gttgtgatca ccgtcttagg ctcagatgag ctggacgctg ttgagtgact
    21241 gctttgtgat gacttaagaa aagacatctc agcctctttt gctttttgac ctttatcaaa
    21301 ttgcttccaa acagcaaaac caataacacc aacaatagcc acagcaataa gacctagtaa
    21361 ggctgatgga aaggctgatt ttttcgtttt agcactattt ccataacgac ttagccttga
    21421 agcactggtc tctctagtcc gtctatggtc agtagcctta aagtgactag ctgtaggagc
    21481 tgatttgctt gaggatagtg acgtcttgac aggaatcact agggtttctg gttgagtcct
    21541 tgaaggctct ggttgagcta ttttttcaga atagctattc tcttgtagcc tttttttgct
    21601 gagcttttct tcaacgattt gtgtgactga tggtgtacct gtttcctttt taaagctcac
    21661 ctgcagctga tacaagcgtt ttaagctatc aaagtctaag ccaacaatat cagcatattg
    21721 ctttagaaaa tgaccaaact tttcttctgg aatgattttg aactggtcaa gctccattgc
    21781 caatagataa tgcgaggaaa tgccagtttt agcttcaatt tcgtctaatg ttatgttttt
    21841 tccgacacgt gtttctctta ataattcacc gagacttgtt tctctcatac gagtacctca
    21901 aaaatattgt aataagacca ttataacaga ttttaagcta tttgggaaag actgtaaaat
    21961 ctgaagtagc tgcatgctca aaaaacaagc ttcctatttc gataatatcc tttaaagcta
    22021 gggtctcaat aatcctagga atatcaaaat aggtctcttg ctctgataaa tgaaggctaa
    22081 attggcttgc cagctgatca atagcgtcta agctttgcat aaaatcccca tacatttcct
    22141 ttttcactag ctctaagtgc tcctcattaa cgtctcttga gcatctaaaa tcggaaatct
    22201 tttttctaat gctgttagac attgcaatag gctgactagt atctgaagaa atcaatacaa
    22261 attggaaatc cctttgaatg tcaacctcta tatcaaagga gtcgtctatc ttgccctttt
    22321 cataccaatc ctgataggtt tttgacgtcc agccaaggag caccgctagg agcagtctaa
    22381 gagctacctg ataggtgagt agagaatact cgcttgacat tagctgaccg cgaaagccga
    22441 ctgctaattt ggcagtcgca acgtccatat caatagatct agacttgatc acagggtagt
    22501 aggtcaatgg agctatctgt acatcatact gcgtctgact tggttgacta tcttgaaagg
    22561 cttcaatagc tgtaaaggct tcttcaatgt caatatcgcc aataatcgtt aagaccatgt
    22621 tagaagggtg ataaaaataa gcatggctgt cagccaataa agagcctgta atgtccctga
    22681 tagactcctt ggtcccagca atatcaacag ctaagctggt attgggaaag aggttctgta
    22741 agataccact gtaagcctga taatcaggat cgtcctgata catctcaatt tcttgagtga
    22801 taatatgttt ttcacgatta accgactcct ctgtaaagct aggagctgct acaaattcct
    22861 gcaaaagtct cagactttct tgccattcat tgacagttga aaagaaatag ctcgttttat
    22921 caaaggttgt aaaggcattt gtttctgatc ctaactgtgt aaatgtaaga gcaatatcat
    22981 taccatcttt atcctcaaat agcttgtgct ctaagaaatg agcaacacct gacggcaagt
    23041 caaacctttg acaattgact gtaaagcttg tgtcaagaga accaaaacga gcagtcagca
    23101 tagctgtttt ctcagaatag ccctctttct ttatcaaata aacccttaaa ccatttgcca
    23161 attgaccgta gtgtaaggtc tctttaatgc tgggatagtc ttttttcagt agtgacgtca
    23221 tcttattttc cctctaaaaa atatacagct tgcagcttga gtagattagc tgtcctgaca
    23281 atatctagct tgctaacctt gtcaatctcg tcaagccaac ttgacaaagt ataggaagga
    23341 tctatataag atctcatgta ttccagctca atcaaggctt tactattatc ctcagatagc
    23401 aaggcgttat tttttagcat tagctttgtt ttcttgacaa ggctgcttga aaagcgcccc
    23461 atcttgatgt cattgagctc tttaaccatt agctgcaggg ctcttgtccg gtgctgtcta
    23521 tctatgccag cataagcctc aaataagcct gtgtaaacat caaatcgact accaatacta
    23581 taggccagcc cctccttctc acgaatttgg gtaaagaagc gagagtgtgt aaaggctcct
    23641 aatagaccat ttaacacaac taaggcataa tactctgctt gcccataaac cagcggaaaa
    23701 tgataggcta gctctaaaac agactgatta agctgctttt gctcgaccaa ttcgttgaca
    23761 acattgacag gctgctgtaa ataaaagaaa tctagctttt tcctgcgtcc ctcaaaggga
    23821 aattggtgta acaattgtac catacgataa tcatcaaaat caccaagaat aaaaatatca
    23881 atctgatcct cattcaacat tttatgaaat tcttgatagc ttgtgtaggc tgtttcttta
    23941 gcaattaact cagtattacc atattttgac agcttcaggc tatcattagc ataaaataat
    24001 tgcttggctt ttagggcact ataataaaag gaatcctcct tatctgcctc gacataggtc
    24061 atcaaatgtc ttttttcgat gtcaaatagt ttgggctggt actgagccac tgataacaaa
    24121 ggagaaaaaa ggatatcctt tagaaattga atcatttcgt ctagaagctt ctctccataa
    24181 aaagcatact gatcctgaat aaaggtaatg tcaatatcca caatatgaac caaacccttg
    24241 gttgacacat gagttgacag gcttgctcca tacatttgtg ctaatttttc tctaaattgc
    24301 ttggcagtag gataggtatc gttagccgtt gctaacattt gagctactaa gactcgcttt
    24361 gctaccgttt tttgattcaa atcacctgaa aagcgaaacg ttatctgatt cgttttaaat
    24421 gttttgtttt ttatcagatg aagctgaact ccctgaataa gtttcataat atttccttat
    24481 taataaatgt gtgatctcta gaattatacc atttttatcg ctattcgttg agtgttaaca
    24541 tcagtctggt agcctatttt gactctttat caaaatgcta tcctgtggct atagtctaga
    24601 ctttagaagg tcagcatttc agcattatta tttagtggct ttttatgcta taatgacttg
    24661 aatgacaaat tggagatgac tatgacatac acactattta ctgactttat taccctacaa
    24721 gctttattaa aggagcaagg tattatccaa agtggtggtg ccattaaagg ttttttagct
    24781 caaacagagg tttttttaaa tggtcaagag gaacaacgac gtggcaagaa gctaagagtc
    24841 ggtgacgtca tcaccattcc atcacagcac atcaagattg agcttgtagc gcctagtcag
    24901 gccgaaaaaa cagcctatga agctgaaaag gcagaaaaag agcgagttgc taagatggtt
    24961 aaacaaatga atcaacaggc taaaaaagca cagaccaagc aagcagctac taccaaaagc
    25021 aagcgtggtc aagctacctc agctgtaaaa gctaagtcta atcaccaaaa gcctattcgc
    25081 ttcccaggat tgtagcatgt ggatcaaaga actaaacctc acccattacc gtaattatca
    25141 acaagcctca gcagcctttt caccgggctt gaatgttttc attggtgaca atgcgcaggg
    25201 caagacaaat tttcttgaag ctatttattt tttgtcagta acaagaagtc atcgcaccaa
    25261 atctgataag gacttaatct actttgacga aagggattgc tctatatctg gaactcttga
    25321 gcgccttagt ggtcgtgttc agctagaaat actgctgtct gataagggac ggatcaccaa
    25381 gattaacacc ctaaagcaag caaagctttc tgattatatc ggagcaatga tggtggtcct
    25441 ctttgctcct gaggatctac agctggtcaa aggctctcct aatcttagac gaaaatttat
    25501 ggacattgac ttaggtcaga taaagcctgt ttacttatca gatttgtcac attacaatca
    25561 tgtcctaaag cagcgaaatg cctatctcaa aagtgttcat cagcttgata atgacttttt
    25621 atctgtgtta gatgagcagc tggttaccta cgggagtcgt gtaatggcgc atcggttggc
    25681 gtttgttcaa tcactagcaa aagaggcaaa caagcatcat caagctatct ctaatggcct
    25741 agagaagctt tcgatctcct atcaagcctc tgtgagcttt gagcaccagc aagagattta
    25801 tcagcaattc atgaaccagc tcaaaaccac tcatcaaaga gatttcttga gaaaaaatac
    25861 tggtgttggc ccccaccgcg atgatctggt tttttatatt aatgacatga acgctaattt
    25921 tgctagtcaa ggccagcatc gtagcctgat tttatcactg aaaatggcag aggttagtct
    25981 gatgaagcaa ttaacaggtg acaaccctat tcttctactt gatgatgtta tgagtgagtt
    26041 agacaatacc agacaaacaa agcttctggg agctgtcaag aaagaaaatg ttcaaacctt
    26101 tatcacaaca actagcttag agcatttgtc tcagctacct aaggacatta gtctctttaa
    26161 ggttaataaa ggaacaatag aacgagattc tatcatgatt gattaactga gcaaactaaa
    26221 aaaagggcac cttaatagtg acccttttta cggttaaatt agttgatact ctatgatttg
    26281 acgataccta agaggatagc gccaacaata aagcaaagga tacctgtaat gacccagcgc
    26341 atctcttttt tggtttttgt ctcacctaag aataaaatac ctccgacaat agagataata
    26401 gcgcccaatt gtgaaaagct aaaagcaatc gccagaccag cctttgaggc tgctagcagc
    26461 atgaagatat ttccaactcc ccaaagcaag ccaacaacac tatttttgat aacatactgg
    26521 tcaaacgata ccttaaacga cataaacatg gctgcaccaa gcaccattcc cactgccatc
    26581 ggtaaaataa ccgacaacac atcaaatttc ataatgttat tgaacagcac agcatacatc
    26641 acatagccgg ttgtcgagta ggttaaggct ctaaagccct ttgaaaaatc atgcaattga
    26701 ttacttgctg cattcgtctc gtcctgcttg cttgaaaaat aaaaaccaac aatcaaaaga
    26761 agtaaggcaa tcgtaccaac gacaaattga ataggcttgg tccactcatg aaagaccagc
    26821 acaccaatca ggctacctaa aactagctga gaaccactag acaagggatt tgctactgaa
    26881 acacccatat actgcatggc atgaaattgc ccagtctgac caacagacca gataatacca
    26941 cctaaaatcc caaaaatcca gagcttcata gacatctcag gtctgactac taaccaaaca
    27001 actagagcaa atagtaaagc tcctatggtc attccaaagg tctgctgtga gggtttaccg
    27061 ccaattttat tactaacaaa gccaatactt ccccatgcaa acattgggac aagtgcaaat
    27121 aaaatacctt ccaaatttac atctccttta caataagttg acacatgatg ttaacgataa
    27181 aagtgctttc atacggagaa ttattatagc ctatttcctt agaaaataca ataacatgat
    27241 gtaaaaaatc atctgctcac acgcttctcc ctaaaaaggt gtcaaagtag ctgacagagc
    27301 ttatttactg caatgctaga ggattattta atgaaaaccg tttgacctta tggctggctc
    27361 tagctggagc tttgttaggg acttttgtga cctgagttcc aaagcaatca gcaactagct
    27421 gactgaaata gcctaagcgt ttgaggagta gagcaagatg attaaccata gcactagctg
    27481 cttgaccgga catgcttgct tctatggtag ctttgacaaa ggatagctca acgatgattt
    27541 tatccagcag tctgccaacc atcttttgac tagtgatgat gtcatctaaa tcaagagcgc
    27601 tgtaaactcc tttttcgatc aatcgactga gatctccatg caagttttga agccgatgcc
    27661 ttgcggtatt gactcgctgt atcgtatcag tcaatgccgg tactagagga catacctcag
    27721 ctctggcaga agcaataccg gatcttatgc ggcaaggata taaagcaccc agatttcccc
    27781 aatagctcct tgtcgttgta gaggtttcat ctttgatttc tgttcgttca acataaaccc
    27841 tatctgaaaa acgtctctct aatactgtca cgatattctt aaagatattc acctcagtag
    27901 tccaataatc aagtgtatca aatagccttg aaaaggttga cgcataaaca gaggcaacct
    27961 ttctggaata gtcccgactc ttttgttcca cctgctcatc aaaggcttgg agaatatctc
    28021 tgacatcatc taaaagacct gttctttcta ggtaagcatc atagctgctt gggacacaga
    28081 cgacatcagc acttccttga aattgaccat tttttaggct gttgcctagc cagttatctg
    28141 tagctgtgac attttgtgat acccctagga tcagctcact ggtattgatt atcatttttt
    28201 ccagctctat gatatcctgt aattccacgc taaatacctc ttttaaggaa tcgctaatac
    28261 cgtcaacttt actttcacgt aaacccgttc cttcaaaggt cttatcactc tccttcaata
    28321 gctgacgact ggcctcatca ataatctgcc aagatttcaa aagtgtcgag cgaccgataa
    28381 tactatcaat ccagcctgac ttttcatgct gagcagatga ggcaagctga agcgattttg
    28441 tgtttaagct cgctaattct gaatcataca tggccagatt gaggcgatta ttattcacat
    28501 atgggatctc atcataggaa aagggatagt ctaggctagc cgaatgagac agcatatcaa
    28561 acaagtcctg ctgaccaact aatctctcca aagaactttg caggctatta aaagtatcgg
    28621 ttaggccatt tgtagcaagc agggctttga tgttttctga aactcgcttt ttcctctctt
    28681 caaaggagtc ttttatggca tcattttttg cctgacattt ttcagtaatg tggcgaatcg
    28741 tttgcaggtc gcctgatata gaggattgaa ggttttgtgc aaggttagtc aggacaccag
    28801 cattgatgac aatcgtttgc ttatcagaaa gcacaccgta ccgagccgat gttgacgaat
    28861 caaagtaatt tctaaagcct aagtacagct cctctacctt agtgtctaat cggttatcgc
    28921 tgtcaatatc aataggcaac aggacattag catgaacaaa ccggccattt acgtctgtca
    28981 tgttgccata ttgatcatac tgatagccat gccacatatg ctgtaagact atatcattga
    29041 ccttttttgt attgacaaca aagacctgac cgactgctcc ctccttttgg tcaaagccca
    29101 taccaatgat gtcatgcgga tccacatagt tgtaaatgcg gtcatgcaag agctttgcac
    29161 gttttctttg atactcatta agcacacgat aggtgttggg gccattgtag atatagactc
    29221 cagagatacg agataagttt ttatcactaa cagaggtaac accgtactga actgtcatgg
    29281 agcctagcga atgaccataa aactcaaatg ttgcgttagg gtattgcttt aatgtcttat
    29341 tggtaaaggt tgctgccttt cggagctgag ctgtcccttt agttggtgtc tggtccggta
    29401 aaagaatgcg catagccata ggcaaatcat tgcctaccca atctgcaacc acatctactg
    29461 ggtgtttctg ccactggtct gggccagtag agccccggta cagcatggtg acatgcttga
    29521 cctgagcata gtctgccttg gtaggatgag ggggaagctt gacatctgtc acgacatagg
    29581 cttgaaaacc tgatatcgaa tcctctatct gagacacata accgatggaa aactcagaat
    29641 tatcatcatc aattaaaact ggtgaaccta ctgtatgttt ttcatactct tcctcagcaa
    29701 tccgttgtct ctgttcgtct gtcaggatca tcattttcac tctcctttta gtagtttttc
    29761 taacttttct gagcgataat tactagcgat ctctaaattt ctttctaaat catatctact
    29821 aaggcgaacc cttaaataag tatctggatc atcattgata atcaggtgaa tagaaaaacc
    29881 tcccattgga ttaata
//
LOCUS       DARYLD010000024        29529 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYLD010000024 DARYLD010000000
VERSION     DARYLD010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29529
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            106..1377
                     /locus_tag="TU651_000927"
     CDS             106..1377
                     /locus_tag="TU651_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL0896939.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            1471..2607
                     /gene="recA"
                     /locus_tag="TU651_000928"
     CDS             1471..2607
                     /gene="recA"
                     /locus_tag="TU651_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL0896940.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            2983..3381
                     /gene="spx"
                     /locus_tag="TU651_000929"
     CDS             2983..3381
                     /gene="spx"
                     /locus_tag="TU651_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL0896941.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            3494..3763
                     /locus_tag="TU651_000930"
     CDS             3494..3763
                     /locus_tag="TU651_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL0896942.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            3760..4179
                     /gene="ruvX"
                     /locus_tag="TU651_000931"
     CDS             3760..4179
                     /gene="ruvX"
                     /locus_tag="TU651_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL0896943.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            4189..4488
                     /locus_tag="TU651_000932"
     CDS             4189..4488
                     /locus_tag="TU651_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL0896944.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            5036..6595
                     /locus_tag="TU651_000933"
     CDS             5036..6595
                     /locus_tag="TU651_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL0896945.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            6692..8890
                     /gene="nrdD"
                     /locus_tag="TU651_000934"
     CDS             6692..8890
                     /gene="nrdD"
                     /locus_tag="TU651_000934"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL0896946.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            8996..9142
                     /locus_tag="TU651_000935"
     CDS             8996..9142
                     /locus_tag="TU651_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896947.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            9170..10105
                     /locus_tag="TU651_000936"
     CDS             9170..10105
                     /locus_tag="TU651_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0896948.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            10118..10612
                     /locus_tag="TU651_000937"
     CDS             10118..10612
                     /locus_tag="TU651_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896949.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            10622..11236
                     /gene="nrdG"
                     /locus_tag="TU651_000938"
     CDS             10622..11236
                     /gene="nrdG"
                     /locus_tag="TU651_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL0896950.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(11694..12425)
                     /gene="yaaA"
                     /locus_tag="TU651_000939"
     CDS             complement(11694..12425)
                     /gene="yaaA"
                     /locus_tag="TU651_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL0896951.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            12879..13082
                     /locus_tag="TU651_000940"
     CDS             12879..13082
                     /locus_tag="TU651_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0896952.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            13084..13537
                     /locus_tag="TU651_000941"
                     /pseudo
     CDS             13084..13537
                     /locus_tag="TU651_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            13547..14221
                     /locus_tag="TU651_000942"
     CDS             13547..14221
                     /locus_tag="TU651_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL0896953.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            14251..14688
                     /locus_tag="TU651_000943"
     CDS             14251..14688
                     /locus_tag="TU651_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896954.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(14911..15684)
                     /locus_tag="TU651_000944"
     CDS             complement(14911..15684)
                     /locus_tag="TU651_000944"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL0896955.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(15768..16835)
                     /gene="pepA"
                     /locus_tag="TU651_000945"
     CDS             complement(15768..16835)
                     /gene="pepA"
                     /locus_tag="TU651_000945"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL0896956.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNPAHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            17180..17527
                     /locus_tag="TU651_000946"
     CDS             17180..17527
                     /locus_tag="TU651_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL0896957.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            17524..17841
                     /locus_tag="TU651_000947"
     CDS             17524..17841
                     /locus_tag="TU651_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL0896958.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            17856..18482
                     /locus_tag="TU651_000948"
     CDS             17856..18482
                     /locus_tag="TU651_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL0896959.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(18785..19498)
                     /locus_tag="TU651_000949"
     CDS             complement(18785..19498)
                     /locus_tag="TU651_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0896960.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            19610..20005
                     /locus_tag="TU651_000950"
     CDS             19610..20005
                     /locus_tag="TU651_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0896961.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            20452..21426
                     /locus_tag="TU651_000951"
     CDS             20452..21426
                     /locus_tag="TU651_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0896962.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            21444..22406
                     /locus_tag="TU651_000952"
     CDS             21444..22406
                     /locus_tag="TU651_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL0896963.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            22521..23405
                     /locus_tag="TU651_000953"
     CDS             22521..23405
                     /locus_tag="TU651_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896964.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICAAGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIIIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            23414..24217
                     /locus_tag="TU651_000954"
     CDS             23414..24217
                     /locus_tag="TU651_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0896965.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(24316..25320)
                     /locus_tag="TU651_000955"
     CDS             complement(24316..25320)
                     /locus_tag="TU651_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896966.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(25606..26247)
                     /locus_tag="TU651_000956"
                     /pseudo
     CDS             complement(25606..26247)
                     /locus_tag="TU651_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(26268..27245)
                     /gene="dusB"
                     /locus_tag="TU651_000957"
     CDS             complement(26268..27245)
                     /gene="dusB"
                     /locus_tag="TU651_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL0896967.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(27232..28104)
                     /gene="hslO"
                     /locus_tag="TU651_000958"
     CDS             complement(27232..28104)
                     /gene="hslO"
                     /locus_tag="TU651_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL0896968.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(28354..>29529)
                     /locus_tag="TU651_000959"
     CDS             complement(28354..>29529)
                     /locus_tag="TU651_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL0896969.1"
                     /translation="LHNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNT
                     ELTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELV
                     GYISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLE
                     LENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLS
                     IIYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTN
                     KSVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYIL
                     KEKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT         8439 a         5367 c         6849 g         8874 t
ORIGIN      
        1 atcattgaaa accattaatt catctaaaat tatttcaatg cttcatggat gattcttttt
       61 ttgttaaaat gagattgaat gtcgaataga taagtaggtg ggaaaatgaa agctgaactc
      121 attgcggtgg gaaccgagat tctgactggt cagattgtga ataccaatgc tcaattttta
      181 tcagaaaaaa tggcggagct tggtattgat gtttattttc aaacagctgt aggagataat
      241 gaagagcgtt tgctttctgt tattgatatt gctagccagc gaagtgattt agtgatttta
      301 tgtggtggtc ttggtccaac agatgatgat ctaacgaagc agaccttagc taagtatctg
      361 ggaaaagctt tggtctttga tgagcaggca ggtcaaaaat tagatgcttt ttttgcacat
      421 cgtaagcagg ctgctaggac accaaataac caacgtcagg cgcagctgat tgaaggctct
      481 attgctttgc aaaatcaaac aggacttgca gtaggtgggt taataactgt agatagggta
      541 acctatgttg tcttaccagg gcctccaagt gagctaaagc ctatggtaaa aaatgagctg
      601 gtgccccttc tttcagctag tcatgccagt ctatattcaa gagtgctgcg tttttttggc
      661 attggtgaaa gtcaactggt gactgctctg gaggatttga ttaagcatca aacagatcct
      721 actattgctc cttatgcaaa gaccggcgag gtaacactgc gactatccac aaaggctgac
      781 aaccaagcat tagctgatga aaggctgaat cgactagagg cgcagctctt atccataaga
      841 actgtagata atcaaccctt acggcgtttg ctttatggct atggggagga taattccttg
      901 gcgcgtgaga cctttgagct attgaagcga agtggtaaga cgataacagc agctgaaagc
      961 ttaacagcag gactgtttca agctcagtta actgattttg cgggagcttc acaggtgttt
     1021 aacggtggct ttatcaccta cagcattgaa gaaaaagcaa gaatgcttgg cattccattg
     1081 ggtgagctac aaaggcatgg tgttgtgagc tcttttacag ctgagcaaat ggctgcacag
     1141 gcacgctgct tgaccaattc agatatcggt attggtctaa caggtgttgc tggtccagag
     1201 gcactcgagg gacagccagc aggaacagtt ttcattggcc ttgccactaa gaataaggta
     1261 gaatctctta aagttgttat aggaggccgt agccgtttgg acgtgcggta tattgctgcc
     1321 ctatatgctt ttaatatggt tcgtaaaact ttattaaaat cagagaattt gctataatta
     1381 ggatagtgta ttttaggaaa ttagtaacta gacagatgtg aggttatgct gtttattgct
     1441 tgctagtcag cctaaataga ggagaaaata ttggcaaaaa aagttaaaaa aaatgaagaa
     1501 atcaccaaaa aatttggtga tgaacgtcgt aaagcacttg atgatgcgtt aaagaacatc
     1561 gaaaaagatt ttggtaaggg tgcggttatg cgccttggtg agcgtgcaga gcaaaaggtt
     1621 caggtgatga gttcaggcag tcttgcttta gacattgcgc ttggagcagg tggctatcct
     1681 aaagggcgta ttattgaaat ctatggacca gagtcttctg gtaaaacaac agttgccctg
     1741 catgcagtag cgcaggctca aaaagaaggt ggtattgcag ccttcattga tgcggagcat
     1801 gccttggacc ctgcttatgc tgcggcgctg ggtgttaata ttgatgagct gcttttgtca
     1861 cagccggatt ctggtgagca aggacttgag atagcaggta aactgattga ttctggtgct
     1921 gttgatttgg ttgttgtcga ctctgttgca gctctagtgc ctcgtgctga gattgatggt
     1981 gatattggtg ataaccatgt tggcttgcag gctcgtatga tgagtcaggc gatgcgtaag
     2041 ctttcagcct caatcaataa aaccaagaca attgcgatct ttattaacca gctgcgtgaa
     2101 aaggtagggg ttatgtttgg taatccagag acgacaccag gtggtcgtgc tttgaaattc
     2161 tatgcctctg tccgtctgga tgttcgtgga acaacacaaa taaaaggaac tggagatcaa
     2221 aaagacagta gtattggtaa ggaaaccaag attaaggttg ttaagaataa ggttgctccg
     2281 ccatttaagg tggctgaggt tgaaatcatg tatggagaag gcatctcacg tacaggtgag
     2341 ctgattaaaa ttgcttcaga tttagacatt attcaaaagg ctggtgcttg gttctcttat
     2401 aacggtgaaa aaattggtca gggctctgaa aatgccaaga gatatttggc tgatcaccca
     2461 gagctgtttg atgagattga ccataaggtg cgtgttaaat ttggcttgct tgaagatact
     2521 gaggaaagtg cagctgcaga tacagttgca gccaaagcag atgagttggt tttagagcta
     2581 gacgatgcca ttgaaattga ggattagtgc ttagtattag attttcagat aaaggtgcta
     2641 aaaagggctt aacagcgatc gtcaagccct ttttagcttg tgtttaatca agctctgtat
     2701 tggtctgctc aggagctagg ctgtacgctt ggataatttg ttagctgagt ttatgttttc
     2761 tttagggatt aactgttaag ctataaaagc cctagaaaaa agggacttcc tacagacaag
     2821 atagtggcat agtaagcttg cttgcaacta gctcaatata ggattttggc cttggttaaa
     2881 gggatcataa aagaaaacta aaaaataggt ccaaagaccg atattgatta gaaaaaaact
     2941 atgctacaat agaggtatca cgagatagaa agtgagaaca acatgataaa aatttacacg
     3001 atttcaagtt gtacgagctg taaaaaggct aaaacctggc tgaatgccca taagctccca
     3061 tataaagaac agaatttagg aaaagaacct ctttcaagag aagaaatttt agctatttta
     3121 tcaaagactg aaaacggtgt ggagagtatt gtctcttcta aaaatcgtta tgccaaagcc
     3181 ttaaattgtg atattgacga gttaagcgta aatgaggtta ttgatttgat tcaggataat
     3241 ccccgtattt taaaaagtcc gattcttatc gatgacaagc gtcttcaggt gggctacaag
     3301 gaagacgata ttcgtgcctt tttacctcgt tctattcgta atattgaaaa tgcagaggcg
     3361 cgtttacgcg ctgccttata aaaagctctg tcagagcttt ttttaatatc ctaacaaatc
     3421 tgaattcttg tttattcaat aaaaataagc tataatagag cgtagcactt aaagttagaa
     3481 agaaggtgta agtatgggat ttacagatga aacagtccgc tttaatttag acgatggtga
     3541 taaaaagcag attagcgaaa cgctgacggc agtttatcat tcactagatg aaaaaggcta
     3601 caatccgatt aatcaaattg taggttatgt actaagcggg gacccagctt atgttcctcg
     3661 ttacaatgat gctcgcaacc aaattcgtaa atatgagcgc gatgagatcg tagaagagct
     3721 tgttcgctat tatttgcaag gaaatggaat agatattaga tgagaataat gggacttgat
     3781 gtcggttcta agaccgtcgg tgtggcaatt agtgatccac ttggttttac tgcccaagga
     3841 ctagagatta ttaggatcaa tgaagataaa caggattttg gctttgatag attagctgag
     3901 cttgttaagc aatatcaggt tgatcgattt gtcattggct tgccaaagaa tatgaataac
     3961 actagtggcc cacgtgttga agcaagtaag gcttatggag ataagattga ggagctcttt
     4021 cacattccgg tttcttatca agatgagcgc ttgacaactg ttgaggcaga gcgtatgttg
     4081 attgagcagg cagacatcag tcgtggtaaa cgtaaaaaag taatcgataa gctggctgcg
     4141 cagctgattt tacagaatta tttagattgt aactattaag gagaacagat gacacataat
     4201 catgatcacg aacacgaagt cattacactt gtcgatgagc aaggaaatga agcattgttt
     4261 gaaattttat taaccatcga tggacgtgaa gaattcggta aaaactatgt tttactagtt
     4321 cctgctggtt cgcaagagga tgaatcagga gaggttgaga ttcaggccta ttcatttaca
     4381 gaaaatgaag acggaacaga gggtgattta cagccaattc cagaggattc agacgctgag
     4441 tgggatatga ttgaggaagt ctttaatagc ttcttagacg aagagtaaca acctgaggca
     4501 ttagctttaa aataataaat agcctagaat cttggtgcta gcagcatggg ttttaggcta
     4561 tttttatggt ttatcagaca gtaggagtga tagctatttc tatgacctct aaatagccta
     4621 ctgttaagag tgtttttagg gtcttgtaga tgttgcaata gcctgtaatt tcgttgaagt
     4681 tacttgctgt tgtctttttt agtttaagcc ttaacaaagc ttataggaaa tgactcaact
     4741 tagcacagca taagccgctt attttgataa gtaaagaaat agccaatagc tacttttagc
     4801 ttaaagctga tcattaccag tacccttagc ttttctgggt attatttcga ataatcttaa
     4861 tgggggtgat tttatcaaaa gactcagtca agaagaaaaa agctttctaa agcattatag
     4921 gctaaagaca ctgcaccgct ttaaagagct gctgacttat gccagcattt gtcataaatt
     4981 gactaaataa tagattttgc tatacttgta atatgacatg tcaaggagaa acacattgag
     5041 tcaattacat caagaagtta tgctggaaaa ggtcaattat ttggtgaaag accacccatc
     5101 gtcacatacg actaagtatg acatgaaggt ccctagttta tataaatttt atatcttttt
     5161 ctttagcatc atagcgagct tgcttacggt tgcggttcct ttttttgcag atactgcaaa
     5221 tagcgttcag tcacaaaatt tatacatcgg aatgatgttg actaaaggtc agattccata
     5281 tagtgacttg tttacaacag gaggctttct gttttttgtg ctcatagctt tgagctatca
     5341 cttgggaaca acggtatggt tggtacttgt tcaagcgctg tgcttttatt tgacaggtgt
     5401 ttatttctat aaattaatcc attatgtgac aggtattcag aaggtggctt taggttttac
     5461 agctatctat tacctattgt ctattagtct tggatttggt ggcttatatg cgatccagct
     5521 tgccctgcct tttgtcttgg tatcgctttg gtttttaacc aagtattttg ctggcttggt
     5581 aaaggacgag gcctttattc tctttggctt tgcagcggca atagccatgc taattgagcc
     5641 taggacgctt cttttttggc tgcttgcctg cattgcgatt attgcttata atgtgtctca
     5701 aaagcatttc gctcgaggct tttatcagct gttagcagct atttttggaa tgcttttggt
     5761 gttttataca gcaggctatt ttatcctcaa tttacagatt ttgagtcctt atttggagca
     5821 ggcgcttgtt tatccgttta gttattttgt gacaggtgat ttatcgctga ttctcggttt
     5881 aacagtccaa ttaggacttg ttcttggctt gggactgtta acggggctgc tgacgtttat
     5941 gaagcagcct aagctagagt ctgatcttgc tatgaaatgg ctactagtct ttgttgtgtt
     6001 tagctatgct ggtattgcgg ctatatcgca tgattttcat acttatcacc tactgccttt
     6061 actgccttat gctttgatct tgctatcaag ctctgttggc cgacaatatg aggcaggact
     6121 taggatggtt agtcatcgtc gtcgtaaggg gaaaaatggt gcgagacggg ttattgctat
     6181 ttatctaaat aagcatttct acgtgccagc aatcataatg ctaggagcgg tttttggcac
     6241 agcttatcag tatgtgacca gctctgctat taatcaagag cgttctcaga ttgctcacta
     6301 tctaagacag aggctaacgg aggaccaacc catctatgta tgggacgata cgtcaaaaat
     6361 ttacctggaa acgcaggcca agtcagcttc acagtttgcc tcaccctttg ttaatctgaa
     6421 aaaagagagt catcaacaga tgttagagga tgagctacta cagaataagg cagtctatat
     6481 tgtggtcaac aagcaaaaag cattaccaaa ggcagtcaag aaaatagtga cagctaatta
     6541 taaaattgac agaaagattg atgttaaggg ctttagccta tatcagaaaa aataaataaa
     6601 atcaatatat tgtgttggta taaaaaaact taacacaata tattgatttt tttgtgtggc
     6661 gtgatataat agtcgagtaa ggagatagga catgataaca ttagaaaaag acaaagttat
     6721 tgttcagcca gctattaagg ttattaaaag agatggacgc ttggttaatt ttgatgcaac
     6781 aaagatctac agtgcgctgt taaaagcaag catgaaggta acacgcatgt caccgctcgt
     6841 tgaagcaaag ctagaagcta tttctgaacg cgttattgca gaaattatcg agcgatttcc
     6901 tacaaatatt aaaatttatg aaattcaaaa tattgttgag catgagctat tagccgctaa
     6961 tgaatatgct attgctaagg aatacatcaa ttatagaacc cagcgtgact ttgcccgctc
     7021 gcaggcgaca gatattaatt tttctattga taagctcatt cacaaggatc agacagtagt
     7081 caatgagaat gccaataagg atagtgatgt tttcaatacc cagcgcgatt tgacagctgg
     7141 gattgttggt aagtctatcg gtttgaagct gctgccagcg catgttgcta atgcccacca
     7201 aaaaggtgat attcactacc atgatttaga ttatagtcct tatacgccaa tgacaaactg
     7261 ttgtttgatt gattttaagg gaatgctggc aaatggcttt aaaattggga acgctgaggt
     7321 tgaaagtcct aagtctattc aaacagcaac agctcaaatt tcacaaatca ttgctaatgt
     7381 ggcctccagt cagtacggtg gctgtacagc cgatcgtatt gatgagtttt tggcaccata
     7441 tgctgagcta aatttcaaaa agcatatggc tgacgctgaa aaatgggtta ttgaggagct
     7501 gcgggaaagt tacgcctttg aaaaaacaaa aaaagacatt tatgatgcca tgcagtctct
     7561 agagtatgag atcaacacgt tatttacctc aaacggtcag acccccttta cctcattggg
     7621 atttggtcta gggacctctt ggtttgagcg tgagattcaa aaggctattt taacgattag
     7681 aattaatggc ttaggcagcg agcaccgtac ggcaatcttc cctaagctca tctttacggt
     7741 caagcgtggg ctcaatttag agccagactc accaaactat gatattaaga ccttagcctt
     7801 ggaatgtgcc acaaagcgca tgtatccaga tatgttatct tatgataaga ttattgagct
     7861 gacaggatcc tttaagtcac caatgggctg tcgctctttc cttcaaggct ggaaggatga
     7921 acaggggcaa gatgttacct cagggcgtat gaaccttggg gttgtaacca tgaatttacc
     7981 tcgtattgct atggaatcaa atggcgatat ggataaattc tgggagctgt ttaacgaacg
     8041 attacacatt tgtaaggacg ctcttgttta tcgtgtagag cgcgttaagg aggcaacgcc
     8101 agccaatgct cctattcttt accaatatgg agcctttggc aagcggctag ctaagactgg
     8161 caatgttgat gagctcttta acaatcgccg cgcaactgta tcattgggtt acattggctt
     8221 atatgaggta gcaaccgtat tttacggtgg gcaatgggag cacaaccaag aggccaaaga
     8281 ctttacaatc actattgtta aggaaatgaa aaaggcttgc gagacttggt cagatgaata
     8341 tggctatcat ttctctgttt actcaacacc atcagaaagc ttgacagatc gtttttgccg
     8401 cctagatact gacaaatttg gcgttgttgc tgatattaca gataaagaat actatactaa
     8461 ttcattccac tatgatgttc gtaaaaatcc aacacctttt gagaagctag attttgaaaa
     8521 ggcttatcca gcagccggtg cttcaggtgg ctttatccat tactgtgagt accctgtttt
     8581 gcagcaaaat cccaaggcct tggaagctgt ttgggactat gcttatgatc gtgtgggcta
     8641 cctaggcaca aatacgccaa ttgataagtg ctatgaatgc cattttgagg gagatttcac
     8701 cccaacagag cgaggcttta cttgtccaaa ttgtggaaac aatgacccta agacagtaga
     8761 tgtggttaaa agaacctgtg gttatttagg aaaccctcag gctcgtccaa tggtcaatgg
     8821 tcgtcataag gaaatctctg ctcgtgtcaa gcacatgaac ggatcaacca tcaagtatcc
     8881 ggggatataa gccttggaga ataatctcat tacacctata tcattgtaaa ggattgcttc
     8941 atgcaagcag tcctttagtt atcaagacag gtctgtaaca aagaaaggga gaaacatggg
     9001 aaaataccag ttagattata agggaatgca gcaagtagag aggtttcatg agaaacattc
     9061 tgttgcaaaa acagacaaaa agtctcgagt acagcagctt agagcacaat ttttagaaaa
     9121 agcaaagcaa tcaaagaaat aatggcacac tcagtaaagg cggtgaagaa tgctagatat
     9181 tggaattgtt gggttaggcg ctatttcaca aaaggcctat ttaccctata tgcgtcaatt
     9241 aagaggaatc aattggcatt tatctactag aaatgcgtta gtccgccagg aggtgggtca
     9301 gctttttggt tgcgcaaggc tttacagcac tgtcaatgag ttacttgagg ctaagttaga
     9361 tggtgtgttt atccatgcag ccactaaggc tcatttagag ctggctagtt tgtttttaca
     9421 aaaaggaatt ccagtttaca tggataagcc tttgacggag gatttcttta gcacgcaggc
     9481 tctttatcaa ttagcagata agcacaatac ctttttgatg gcagacttta atagacgctt
     9541 tgcacctggt gtcaagaagt tgtcaaccct gtcaaccaaa cgtaaagttg ttgttgagaa
     9601 aaatgatatt aatagaccag gtgacaaaca gtttaagctt tttgacttct ttatacaccc
     9661 tttagataca gctttatttt tagttgatag gaggcttgtt gcaggctatt ttcattatca
     9721 gctgactgat aatgatttgc taagtcaggt tagtgtaacc ttaaggacag aacagactat
     9781 tatttcagca gctatgaatc tacagtcagg tagcaggcgt gaggtgatgg aggttcagac
     9841 acctaaagag acctatcacc tagaaaatct agagaccttg cgagcttatc gaggggttga
     9901 tcaagagatc aagggattta gtgcttggga tactacctta tctaaacgag gctttgaggc
     9961 tattgtggat tcttttttac aggctgtcaa ggatggtgtt aaccctgtca agccagagac
    10021 aagtctgttg agtcactgga tttgtcacca aatttgtcaa tctcatgaag ctgatggcat
    10081 attagatgtt tctcttccct tataaaggag tgataatatg aagctacgaa gacctaaaaa
    10141 gcaagatgaa gcgtctgttt tagaaatgat ggcagagttt gaagactatc agtctcctca
    10201 tgatggtggt ttttggaacg ctgagcattt tgattatgaa aaatggttgg aatctaatgc
    10261 tctgatggag gctggcttag ctatccctga gaattgggtg cctgccatac agctcgttgc
    10321 ctttgctgat caacaggcta ttggatttgt caatgtacgc ttgagattaa acgaacagct
    10381 actggtaaaa ggtgggcata ttggttattc tgttagacct agccagcgtg gaaagggcta
    10441 tgcaaagctg atgctaaagg aagccttgca gcttgctcgt caaaagggca ttcgtgaggt
    10501 tttagtgact tgtcattgca gcaatagtgc tagtcggtct gttattttag ctaatggtgg
    10561 tcagctgaag gattgcaata agggtattga acgctattgg ataaaagcat aagaggcaat
    10621 aatgaaggaa aactgttgga attctcccaa accaaaagaa tggacatcag aggcattaag
    10681 ccaaggacgc gttattgatt ataaggcatt taattttgta gatggggagg gagtgcgaaa
    10741 ctcactttat gtttcaggct gcatgttcca ttgtaagggc tgctataacg cagcaacctg
    10801 gtcttttaag gcgggtattc cttatacgaa agagcttgag gagcaaatta tgactgatct
    10861 tgcaaagccc tatgttcaag gtttgacact tttgggcggt gagccctttt tgaatacggg
    10921 aatattgatt cctttgatta agcgtatcag aaaagagctg ccagaaaagg atatttggtc
    10981 ttggacaggc tatacctggg aggaaatgat ggaagaaacc caggataagc tagagctgtt
    11041 aagcatgatt gatattttag ttgatggccg ctttgatatc accaaaaaga atctgatgct
    11101 gcaatttcgt ggatccagta atcagcgtat catcgatgtt aaaaagtcac tggctgctgg
    11161 agaggtggtt atttgggata agctaaatga tggtgatcag tcctttgagc aaatgagccg
    11221 cgatgatttg atttagtaga gacttatcaa catcactaga cttgaaagct aataatgaaa
    11281 gcatgatttt aggctcctgt ggtcttgctt aaccaatcta ataaggggtt ttccccacat
    11341 tatcctcata cttatccaca ggttgtgaat aacctgttgg tttgtggata aaaaagagaa
    11401 ttaaggggtt ctttaattct ctaggcctga aaaagggttc tttttgatgt tttttcttaa
    11461 aagaaagaga ggcaagtgac ctctcttgaa atagtatact taggctttaa gcctagcttt
    11521 caatatctct gaatgtctga ttttcttagg agtcaggcat tttttaatgg cgatgggaag
    11581 tacggcttgt gggtcgcttt gtgtgctaag aggctttctg agctgctata tgtcaatgat
    11641 tggtgatgtg acagctgagg cttgttcaca ttctgaaagc actgatgttt ttcctagctt
    11701 tcttttttga tgtagtagta attagtttcg gttgatagct cctcattata gcaaaagcca
    11761 gcaaagctca gctgcttaag tgcttccttg gtttggacat tgttttctag acaggctgtt
    11821 agaaaggctc ctcgagcttt ttttgaaatg gttgaatgcg tcttgagctg tcctgatctt
    11881 tcctccataa atttgggact tatccacagt ttttgatatt cctttgaaaa aacatctcta
    11941 aactcgttgg ataacagaga aatgatttgc ttgtgatctt tagcaaactg atcgtagata
    12001 gggcgccaat aatgcttaag gctttgccca ttgatggtta ctttagtgtg aaaatcatgc
    12061 cggtgctctg cgattttctc atcagtaggg ataatgccat aaaaagacga ggtaatgtag
    12121 acctgctttg agaggtagtc ttgctggtct ttagagagat tgtcgcgctt gagatgacgg
    12181 tacatgagcc cattaaagag ctgataagca ggataagcag aactctgccc ttgagctatg
    12241 gcctttagtc tcttggcttc cttgcttgct gcttctatac ggatgctgta ggcccttgct
    12301 agctcctcta gggatagttc agccatagcc tctaatatgg gcaggctttt ttggggaagc
    12361 tgatgtggat agcaaggtgg aactggtttc atttctttag ctgttggaat taaaaaagtt
    12421 aacataagtt tattgtagta aaggcggcaa ccttctgtca agagtgggat acatttggtg
    12481 gttatgtcat atgaaactaa tttttatatt ttttacattt tgattagttt ttaaaaatat
    12541 agtgatttag tgttgcataa cctctctaag tatgttaata tatactcaag tctgtttgat
    12601 aaacagaagc tcaggtcaag tgagtgttcc acttacaata acgcagttga tgatggggag
    12661 actcagactc agactcagac tcagactcag agtcaaggaa aagaaatata gtcttgtagg
    12721 attacctaca gggctttttt ctattttgaa ttgagagatc aatataaggt gatgtgctgt
    12781 tttttattac cttaaacatt tggatattgg ctattgacaa aaagtgtaaa ggaaactata
    12841 ctatatgtgt aaagttaact tgacatattg gaggaaccat ggaaaatcgg atacaagaac
    12901 tccgtaagtc acgagggatt agtcaagctg atttggcaga tatgatgtgt gtcactaggc
    12961 aaaccattat ctccttagag aaaggacgct ataatgcgtc attagagctg gcctataaat
    13021 tagcgacatt tttcaatctg actatagaag acgttttctt gtttgaagag aagggagaat
    13081 gagatgatat ttagtgattt aagcgtcctg ctgactcaaa aaagccagct agcctatgcc
    13141 aaaaggctga agtatatggg ctttttcgct ctctgtttag gcggtttgtt tttgttgctg
    13201 gcctttgacg tgagactgac gagctttgct cagggaatgc tggtagggct tggtagtggt
    13261 agcttattat taggtgttcg tgctttttca gattgccttt aatcctcaaa ggctgagagc
    13321 ctcttatatt aaggcttatg atgagcgtca tcaggtagtt atcaagctag ctgctgtatc
    13381 aaccttaatc ttattagtgg tgttgattat tggctgtttg tgcttgaatg ttttttggag
    13441 tttggttttt ggctttagag tatttttaga gatttgtctg tatacgatct tgcttggttt
    13501 tttaggcatc aagctattgt tagagcatat gatttaggag gcttcaatgg aaacaaaaca
    13561 ttcagcagta aaggtcatca tcagtaaatt aaaatggttt ggcttagctc ttcttgtgtt
    13621 tatgcttgag caggctccaa catttttgat aacaaaagaa cagccaatgt ggcagacact
    13681 tcttcttgtg gtcatttttc ttttgattag tggaggtact tattacctag ctgtgaagct
    13741 tcacattgtg ggagatcaag ctattcctaa gaatgactat cgggcacttt ggattggttt
    13801 gggagtggta gctgtctttg ttgtcaagat gattggtggt attctgttgt ttttggagca
    13861 tggtccggga gccaatacgg tcaatcaagc tgccttagaa caggcaggct tatctccgat
    13921 tcttatggtt acgctagttg ctattgtggc accaattgtg gaagaaattg cttttcgagg
    13981 gctgctttat gggaagctct ttggtgcaga gtcttatctg ggcttgattt ttagcagtat
    14041 catgtttggc ttgattcatg tgccaacaga ttttggcagt tggtttatct atggcggtat
    14101 ggggctggtg ttaggctttg ttttccataa aacaaagaag gtcgaataca cgatattgat
    14161 tcattttttg aataatgcac tagctgttct tatcatgctt ttgctgcctt atcttcagta
    14221 gtactgcttg agtaatgaag ggggtaatga atgaaaaatg atcgttggat tgacaaaaaa
    14281 tatcaacgtt gggagaaagt gtataagaga cttggtcatt ctttactgac aatcggtgtg
    14341 ttggtaggga cttatgggat ttttttgatt attcaaggga atcatcaaac gggctttctc
    14401 ctttttatcc tggggcctat actattgatt gcgtcatgtc tttgctatta tgtgtttaca
    14461 gagccaacgt ctttacgaga atatctgatt aatagctatg atgagcgtaa ccgagctatt
    14521 cgtcagaaag cacaggccta ctgcttttgt ctatttgctt ttctcttttt gatgcttgcg
    14581 atattctttc caaatatgac gatcaaggag ctttttgggt ataatcttcc gttgattgtt
    14641 ttcaatctgt atgtcatgat tagagcctgg gttagtaaac acatgtaggt catgttaaca
    14701 caaaggagtc tagagcaagg gctttgaatg aaactatttt tctaaaaacg caaaaaatcg
    14761 cgtgcagtaa cagattaggc catgttactg catgcgattt tgttgtttca aacgtgagct
    14821 cagaatgaca tatccttttt agaaagaata ggtatttagg gctgtcttga gctagtctta
    14881 ggtaatgagc ttggagctca ttggtgatgg ttaggatagg tctttagctt ttttgatcgt
    14941 tgtgtcaatg gcagagcaga cagaatgtgt caggcctgtt ttttcaagat ccatcaagcc
    15001 tgcaatggtt gtgccgccgg gactgcagat cttatcaatc aaatcatggg gactatctgt
    15061 gctgactagc aggttcttgg cgctagctag gacagtttga ctaacgatac taagggcctt
    15121 gtctttaggc agtccatttt tgactccggc ctttgccata gcttcgatga aaaggtaaag
    15181 ataagcagga cttgaccctg ctagagcagt aaaggtatca aaatcctttt cagctatttc
    15241 aaaggttgtt ccaaagctgt tggttagctc tttagcagta gctaataaat cagcagttac
    15301 taagtcatta ccagtcaaag cagtggtgct ttggagaatt tgagcattca tatttggcat
    15361 gatacgtagg agtggcaaat gagagcttgt taattgagct agtctgtcta aggaaatacc
    15421 agcagccatt gacatgatag gctgtttgaa ctgtagaggg ctaagaacag tctcaaagag
    15481 ctgtggcttg atccctagaa tgatgaagtc aacctgatcg atcagctctt ggtgagattg
    15541 ggcgtagctt aggtgcaatt ggccagcaat ttctttagag cgagctaagg atgagcctga
    15601 gatgattagc tcgtgtggtg tgtgtgttag gccttgaatg atagcagttg ccattttgcc
    15661 aacaccgata aatccaattt tcataataat gttcctaaaa atgaataaag gctcaatagg
    15721 ctagagtgct cattgaacct tagattcgca ttttagcctt atccttccta gtatttcttg
    15781 attaaatcaa ctgttgagcg gtcaagcttt ttgacaatgg cttgcaaaaa ggcctgtgct
    15841 tctacgaaat catctaaggc gtacaagctc tgatgtgagt gaatgtagcg agcgcagaca
    15901 ccgattgtgg ttgaagggat accgccattt ttaaggtgag cagcaccggc gtctgtaccg
    15961 cctttaccac aataatattg gaaggcaacc ccagcctcct cagcggtggt taataggaag
    16021 tctcgcatgt tcttaagcat gatgtgtccg ggatcgtaaa agcgtagaag ggttccatca
    16081 ccaatatggg caggattgcc ataaatatca ccagcaggtg agcaatcaac agcaaagaaa
    16141 agctcaggat caaatgtagt ggctgacaca tgggcaccac gaagcccgac ttcttcttgg
    16201 acatttgctc cagcaataag ggtgttgtga agtgtctggt cttttagggc ttctagcagc
    16261 tcagtgacca tgagaacacc atagcggttg tcccaggcct ttgagatgat attcttttta
    16321 ttggcagtta aaatggtttc agactgcggt acaataatat ctcctggtgt gatgccaaag
    16381 ctttcggctt cagttttgtc tgtaaagcca ccatcaaaaa caatatctga aaccgctggc
    16441 agactagcag caccatttgc cccgcgcaga aaatggggag gaactgagcc tgaaataaca
    16501 ggaatggctt ggccagcgcg agtgtataag gtaaagcgct gtgagctaac aactagtgga
    16561 ttccagccgc caatttcaac aacccgcagt gttccatcag ctttaatctc gctcaccata
    16621 aagccaacct cgtccatgtg agccgcaaca agaatgcgag gagcttgatc cgccttgctt
    16681 tcttttatcc caaatatgcc gccaagtcca tcaacctcca ctcggtcaac aagcggcgtg
    16741 atcttagcgc gtaagtaatc ccgaacagtg tgctcgtagc cggcgatgcc gtctaattca
    16801 gtaacttctt taatttttga aaataaatca atcatttgta tactccattt gtcatgtaag
    16861 attaaaggta tcacgtctgc ctctattcta tcatttttta gtgaagaatg ggaaacagct
    16921 tgagcatagg aaaagagttt gggagattag gtgtgtcttt cttgcttgat aagctgctta
    16981 ttatcagttt gattcagatg agataactgc tggtattgat ggaatgaaac agctatgcac
    17041 aacagccttg acaaggatcg acaggcctga gctgtcttat gctatcaatt gcacttaggt
    17101 agagcagtag cctgatattg atgtgattag ttgctcttgt caggtggttt attagtattt
    17161 cctaaagtgt cagctagtct tggctgagat tgttagcttt tgctctagcc tattattccc
    17221 tttttgtgat aaaatgaaag gtatgaatgg aaaaaagaca cgtattgttt caggattaat
    17281 tggactgggt ctgctagccg gcttgggatt gaggcttaag gaagtctatc aagaaagaga
    17341 gcgtcagaga gtattggttg aattgcgcgc ctttttctca gccttaggag agattgaggt
    17401 cttgtacatc aactccttta gctcaaagcg tgatgatgtc actggtggcc ttgtcatgac
    17461 agatggtaag acctatactt accattacca caaaggaagt attgatttta aagaggattt
    17521 gacatgatta ttccaacatc taaggaagaa cttgctaggc taattgagac agagcctagg
    17581 ctggttttgt tttttacagc agattggtgt ccggattgcc agtatatcta tcctgtaatg
    17641 cctgagctag aggctgaaaa cccggatatg acctttgtcc gccttgatcg cgatgatttt
    17701 atcgatttag cgcaggattg gcaaattttt ggcattccaa gctttcttgt tatggaaaag
    17761 gggcaggaga agggccgttt ggtcaataga ttacgaaaaa caaaggctga gattagtgac
    17821 tttctagcag cctatcacta agaggagaaa atgagatgat ttttgcatat aataaagagc
    17881 aggtcggtga tgttttgatg gtgatactag aggataaaaa agacatcaag cgacaggttg
    17941 agcgtaaggg gagagtagcg cgtgtttttg cagaagagac agggcaaacc cttgcttgga
    18001 atatttttga ggcgtcagcc ttaatcgctg ttgagggaaa tgggcaggtt ttcttgtctg
    18061 aggaggagtt agcgatttta aatgcggagc ttgctcaaga agggtttact gaacgattag
    18121 aggctagccc agcccctgtt tttgttgtgg ggcaaatcat tgagatgatt cctcacccag
    18181 atagtgatca tttgaatatc tgtcaggtac agattgctcc tgataaggct gtgcaaatcg
    18241 ttgcaggagc acctaatgct gctgttgggt taaaaacaat tgttgccttg ccaggtgcta
    18301 tgatgccaag tggcagcctt atttttccag gaaagcttcg tgggaaggaa agctttggta
    18361 tgatgtgttc tccacgcgaa ttggccttgc caaatgctcc acaaaagcgt ggtattattg
    18421 agcttggtga tgctgcagcg gttggtgaag cctttgatcc tgctaagcat tggcagagct
    18481 agcaggactt gatcagcatt aaaatggtgt ttagtccttc ttttgcttgg tgaaaagcct
    18541 ttggaccttg agccatgcag tgctttttgc tggtctgtga ctgtctttag cttcaggatc
    18601 gaagcattag agtagctgct taacttattg tcagcgctgt tgattgcagt agcgctatgc
    18661 ttgtgacaag tgaaggcaaa gcctatcaat gcccttggct agggctaaaa attgtcttta
    18721 gagtcacttt tgaggtgagt agctcgctaa tttcggtatt gaacggtgct taggtaccgt
    18781 ttttttaagc tttgctgagt gtgacatgct gaaaaaaggc catgtcttta tatggctttt
    18841 ggtcacagat ggctaattca atcgtccgca acacttccag ccaatcaggc ttagctttaa
    18901 cctcatttgg ttgaagtccg tagcatgtcc gcagtccacg atagccttgg agcttcaaat
    18961 cggtctttct gagtaagtca tcaatactgt aggtctgacc tgctgcaaag gataaacttt
    19021 caaaggcttg tccatttagc acattaagtg ccttgtcata gtcgtgttca aaaataacag
    19081 agtggagaac ttttccgact tgattgtgct tgatgagtga tagctgccct ttaggcttca
    19141 atagacgttc catctgagct aggtagatcg catgctcttt tggggcgata tattctaaga
    19201 cattgtggca tatgatcata tcaaaggctt gatcaggcag tttttctagc gcttctaatg
    19261 aaccttttat tttatgaatg ctttcttgct tttgggcaaa taataggtca ggatttggct
    19321 caattgcagt tacttcattc tggacggcta atgcctctgc tgtgatgcaa aagcctgctc
    19381 cgaaatctaa aatagtcttg cctgctatgg ggcctaattg ggcaaagatc aaatcataca
    19441 tgagctttcc ccagggcctt gtgagcatgt cttgataggc tttaagatta atagtcatta
    19501 tctagttttc ctttctttag ctgctgtgag ctattggcag gatttctaaa cttcacagct
    19561 tgtccttatt ttaccatgtt ttacgaataa taagataagg aggtatgaca tgtacaataa
    19621 agtaatcttg ataggccgtt tagtggccaa gccagaatta aacaagacat taacggataa
    19681 gcaggtcgtt cgatttacct tagcagttaa tcgtcggttt aagacgacga ctggtgagcg
    19741 tgaggtggat tttatcaatg ctgttgcttg gggaggtttg gctgaaacct tggcttccta
    19801 tgctagcaag gggagtctgc tgtcacttga tggcgagctt cgcacacgaa aatatgacaa
    19861 ggcgggtcag actcattttg tgacagaggt tttgtgtcat tcttttcaat tgctggaaag
    19921 tcgagcgcaa cgagctatac gtgaaaacaa cgctgctaat gatttgattg atttggcttt
    19981 agaggaggaa aagcttccct tttaaagaca gctgctagct tactgtcgct aagggagtca
    20041 gacactagca ttgtgtatgc tagagatctc aacataatct aaaaaatgac aacgattcta
    20101 aaaaaaatct tgacacgtct tagaaaaagg tttacaatgt atgacaatta aaatgaaaga
    20161 aaacaggagg tgctggtatg gtagcagtta gcacagctca gacgatgact aagcgttatt
    20221 actttagctt ctttagatag tgtttgtaga catgagcgca tggatacaaa cacactgaac
    20281 gttatgtttg tatctatggg gctaagggct atttgagttg tttgtccaca tagatgatat
    20341 ctcttctaag tggacaccat acagcatgta ttttgttatc tcatgatacc tgtataggac
    20401 catttagatt atctagatgg tcttattttt atgcaagaaa gaggaaatga catgagattt
    20461 aaacagttat ccttaacagc ctttataggg cttttggcaa tgctgctaac ggcttgtcga
    20521 caagaaacca accaaacaca tcaagctgct agagttggga ttattcaata tgctgagcac
    20581 tcagccctag atgctgcgcg tgagggtttt attgaggcgc ttgagcaggg cggctttaga
    20641 gaggggaaga acctgaccat tacaaccaaa aatgcacagg gtgatcaggc taacctgcaa
    20701 acaatggtgg agcagctggc gggtaagaac gatttgcagc ttgcgatcgc aacgccggca
    20761 gcgcaggcgc ttttaaatat ggactcagag acaccagctg tatttacagc ggtaacagat
    20821 cctgtctcag caggtctggt tgatacatta gctaagcctg gtgggaatat gacaggctct
    20881 acagatgcga ctgatgttga gaatcagatt gatttgttga ccaaggcgct gcctcaagct
    20941 aggacagttg ggattttcta caattcaagc gaggtgaatt cggagataca ggctaagaag
    21001 gccaagaggg agcttgagaa aaaaggctta aaggtcctta tgaaaaccgt aaccactact
    21061 aatgatgtgc agcaggttat gacaagcttg gctagtcagg ttgacgctgt ttacctgcca
    21121 acagataata cggttgcctc aacagctact actattgggg atattttaaa ggaggccaaa
    21181 attccttcaa tgggaagcga tgctgcttac ctgagtgctg ttttgttcac ctcaggtgtt
    21241 gattaccatg ctattggcat gcaggctggt cagcaggcgg tagatatttt aaagggtaaa
    21301 aaaccagcaa gcattcaggt tgctaagcct caaaaggcaa gcattgctgt taatgatgat
    21361 atggcaagac ttctgggcat tgaccccgag gtgatcaagg ctcttgcaag taacggagcc
    21421 aactagcgtt ttaggaggaa ggtatgaaaa aaggaagcta tttaatactg ttagtgcttg
    21481 caggcttcgt tttggtggct tgtcgttcga cagctagtcc tcgtaaggtt aaccaatctc
    21541 atgttaacat cggtatttta caatacatgg aacatgattc gctgacggca gctcgtcgag
    21601 gctttgaagc gcaattaaag gcagcgggct atactaaggg agacaagctg agccttcatt
    21661 atcaaaatgc acagggcgac caagctaatt tacagacgat ttcagagcag ctagtgaagc
    21721 aaaatgattt gatcttggcg attgcgacac cggcagcgca agccttagcg accgtctcat
    21781 cagatagacc aattgttttt acagcagtaa cagatcctat ctcagcaggc ttagtggata
    21841 ggatcaaaaa gcctggtggc ttgataacag gaacaagtga ccaggcgccg attgcaaagc
    21901 aaattgactt gttagcccaa gccttgccag aggccaaaac tattggcatt ttatacacag
    21961 ctagtgaacg taatgctgag gtgcaggtaa aggaagctga aacgctactg accaaggttg
    22021 gttatagggt tattaaaaag ggaattgcca cttcaaatga tgtgcaagat actgctgcaa
    22081 gcttgatgag agcagtagac gcgctttttg taccgacaga taataccgtt gcttcaacca
    22141 tgacaatgct gggtgagctg tcattggcta ataaggttcc aattattggt ggctcaacgg
    22201 atatggttga tgcaggtggg ctcttgacct atggtatcga ctacgagagc cttggtagac
    22261 aggctggaga aatggccatt aagattttaa gaggacagga tccagcaagc ctagcagtgg
    22321 agtacccaaa aacagtcaag ctacatatca atcaagcaat ggcagacaag ctagcgattg
    22381 atacttccac attatcagtt gactaaattg ctaggttaaa ggctaaatga ctgatctcta
    22441 gccagctggc taaatgacaa agtcttaacc agttagctta gcttactatt aacgattcat
    22501 atgacaaaaa aggagaaatc atgtcactca ttttatcgag cttatcacag ggcttattgt
    22561 ggtctattat ggcaattggt gtttacctga catttcgtat tttagatatt gccgatttaa
    22621 ctgcagaagg ttcctatccg cttggggcag ctatttgtgc agcgggtatt gtatcaggtg
    22681 tttctccctt gctggctacg tttttagctt ttattggagg cttgctggca ggccttgtct
    22741 caggattagt tcacaccaaa ttaaaaatac cagccttact aacaggaatt atcactctga
    22801 caggcttgta ttctgtgaat ctaaaggtgc taggaagagc caatgtggct ttattacgtc
    22861 aaagaacttt agttacccag ctctatgatc taggctttac caagcttgca gcggtgctaa
    22921 ttatgggctt tgtctttgtg accattgtga tttttttatt agccctgctg atgaaaactc
    22981 agcttggcct agctctgcga tcgaccggag acaataatcc aatgagtgaa gccaatggta
    23041 tcaaaacaga tcagatgaaa atcatggggt atatgctatc taacggtttg attgccctat
    23101 gtggtgcctt gctttgtcag aataatggct atgcagattt aaatgctggt gttgggacaa
    23161 ttattattgg gctggcttcg attatcattg ctgaggtgat gattaggcag ctaagcattg
    23221 gctggcgctt agcttccatt gttttaggct ctattgttta tcgcttaatt attctagcta
    23281 tcctagccat tcccggtatg gatgcagatt tggttaagct tttttcagcc atgctattgg
    23341 cagctgttct ttttgtgcca gaattacagc aaaggcttcg ccttcgaaaa acaagtttag
    23401 gataggagaa atcatgtcag caatattatc aattaaggct attcacaaaa catttgaagc
    23461 aggtacgatt aacgaaaatc atgtcttgag aggcttatct ttggacattg aggaggggga
    23521 ttttatctcg gttatcggtg ggaatggcgc tggaaaatcc acattaatga atactctagc
    23581 aggcactctg gcttttgatc agggcgatat tcttttagag ggaaaatcaa tcaagcattt
    23641 atcagccgct aagcgtgcca aggacatcag tcgagtgttt caagacccta agatgggaac
    23701 cgcttcacgc ttgaccattg aggaaaatat ggctattgct taccgccgag ggaaatcaag
    23761 ggggctaggc tggggcgtta aagaaagaga gcgccagatc tatcgtcagg ccttgcagga
    23821 attaggccta aatctggaaa accgtcttaa ggccgagaca cagtttttat caggagggca
    23881 aagacaagcc ttgaccctgt taatggcttc cttagcaaag cctaaggtct tgttgctaga
    23941 tgagcatacc gcagctcttg atcctaagac cagtacaatg gtaatggctt tgacaaagca
    24001 gcttgttgag acacatggct tgacaaccct gatgattacc cataatttgg aaaatgctat
    24061 tgcttatggt aatcgtctgg tcatgctcca tcaaggtaat attgtggtgg atattaagag
    24121 agaagagaag gccaagctga cggttgacca cttgatggca ctctttcacc aaaatagtgg
    24181 tcatacgctc cttgatgatg cacttgtttt gggataggct aggtgagggt tagctctgtt
    24241 ttcaaatagc agccataatg aaaaggctta aagccaacgc ttctagaaac gctagctcaa
    24301 gccttgttat aatacttagg agatttttct aagagtgata aagccatgat gacgtctatt
    24361 gtagtcaaag gatttgtttc ggatgcgata agcctcattt tccacaattt caattgcctt
    24421 attcagctgc tgaatggtaa tcgcctcatc aatctcatga aaagcagtgc tataataatc
    24481 ctcactaaca cgttgattgc ggtctttata ggtattttta tgctctgtta aaatggcctt
    24541 agcctcagca cgttttgcaa tggtatctat aataccttga ccatatgctc tagcctcttg
    24601 aaggattgac agcatattgt ctagagaata tgcgtttgct aagcggctga caaagctatc
    24661 agcgacctca ggacttaaat taataccatc taagtgataa atcatctctg ggtgtagctt
    24721 taggtaatac tgcaattcgc ggaacaaaag cgctggaatt ttcgacgaat ccctatatgg
    24781 attgagctga atctcctgac tatgtagcct attgataaaa tcgtccttga actgcttaat
    24841 agcatcgtag tctgattttt ctagctctgc tttaatattg gctagaatct gggcgtctga
    24901 ataacgacga tagcttgata gtgaagcagc aggcctacta gtattggaat ttcgagaagc
    24961 ttctgctctt ctagtctctt tgcttggtgt ttgctgctta tttgactgag tctcctgctc
    25021 ggttagtcgt agctcagggt gtaaacgact aatattgtta agaaattggt taacctcata
    25081 ttctgatgaa aactttagcc taggtctggc cttgaccttc tcaatagcct tgtcaataat
    25141 ccttttcccg taccttttga gattactgtc agactggatc aaataaagat taacatgtaa
    25201 gtgatcttga ctatccgcct tagataagct gttaccaagg ccaaggcttc ctaagagcgt
    25261 agctagtaac agcaggtgtt ttactagact acgctgaaca atattgtgac gactaagcat
    25321 aagttatttt cccattctat tgtaatatac cagaaaatgt tatcaaaata aagataagat
    25381 gtcaatgtca ttaatggtgg ttaatcttta attaatggtc gttaatctag tatatcagag
    25441 agctagctta ggctggcagt ggtcattctg tgcgtcttgg tacgaaatgc ccaagcagat
    25501 gcagctcact agaatgatca atagcctcaa cacaaagccc cttacagctt gacacaagct
    25561 gtaaggggct ttgttgtatt aacagataac tcaaatcctt gctttttata ataaatctaa
    25621 ggtttttagc ttgtcatcaa tcatgtgcag aacggttgcc aaatcctctg ggttttgcac
    25681 gaaatcaagc ttgtttccat caatcttcat cttaggtgaa acgtcatatt gctcatacca
    25741 gcttgggtat tcaccatgta cctgatggta ataggcttct aagtcaggat tgtcgtcaac
    25801 ctgctcaaaa cgtctgccgc gcttttcaat gcgctctagc atcttctcaa aggagacatc
    25861 aatataaatc agcagatcag gccgttttta aggcattcct tcaagctcct ctagcatatt
    25921 ggctaagagc tcttggtaaa tttcaagctc tgtcttggta acatttccat ttttatagtt
    25981 aagtgtcaag aagagctcat cttcaaagat tgagcggtca agaatattat tgtctgcctg
    26041 gtaggcttct ttaatagatt tgaagcgctt gttcaaaaag aaaatttgta gtaaaaaggc
    26101 atatttttta gggtcttggt aatacagatc aagaacagga ttgttatcaa cagcctcgta
    26161 aaatacctct gttcctaaat gctcacccag tgcagcagca agggaactct tgcctgcgcc
    26221 gattgttcca gctaatacaa tcaacatgtt tctccttcta tgtagtctta gtgtatttgt
    26281 gcaaaaatcg tttcaacctc agctaaggtt ttagcgcgtg aaacggcact gcgaattttg
    26341 gcagcgcctg ctgtccctcg caggtaatga ggggctaacc cacgaaattc acgaacagca
    26401 atagcttctc ccttgagcct gatgaggcgc ttgagatggt ctttagcaat atctagcttt
    26461 ttagcaaagg gcagctctgg caaaacctct cctgtctcaa agaagtgatt aatttgggtg
    26521 aagagataag ggttgttcat agctgcacgg ccaatcatga ccgcatctac accaatctcc
    26581 tcaatcatga acctagcgtc ctgaacagtt ctgacatctc catttccaat aaatggaatc
    26641 ctggtaatag ctcttgagac gcgtgcaagg gtttcatggt cacaggtgcc agtatacatc
    26701 tgctcacgag tacggccatg catggcaaga gctgacacac cagcagcttc agcagccaag
    26761 gcattctcaa cagctagtga gctgtctgcc cagccggtac gcattttgac agtcagtgga
    26821 atgtctaaaa cagaggttac ctcctgaatg atatggtaaa tcttatcagg atcgcgaagc
    26881 cacttggcac ctgcttcatt tttaaccacc ttgttaacag gacagcccat attgatgtca
    26941 acaatgtcag ccttggtatg gctctggata aaatcagccg cacgctttag tccttcagcg
    27001 tcaccgccaa atagttggat tgacatgggg tgctcattgt catcaatatg aagcatatgc
    27061 agggtttttt cgttattata gagaagtccc ttttcagaaa tcatttccat gacaacaagg
    27121 cctgcaccaa attccttggc aatcgtgcga aaggccgaat tggtcacacc agccataggt
    27181 gcaagcactg tacggtgagg gatttccaca tgaccaatcc taaagggtga gttaagcctt
    27241 gtcattgatc agcacctcca aatcagtttg gtcaaattgg tacttggtgc cacaaaattg
    27301 gcaaacaatt tcagccccct tatcctcgtt tagcattgtc aacaggtcag ctttagggag
    27361 gctcattagg gctgacgcaa agcgctctct tgagcagtca cactgaaagc tcagctgctc
    27421 ttcagctaat cgcttgtaag gctcttcacc ataaatagct gctaacagag cgtctatatg
    27481 attttccgac gctagaaggg ttgaaatcgc aggcatttcc tgaatgcgct tctcatagtg
    27541 gctaatctct tcgacagaag ctccaggcag cacctgcagc ataaagccgc cagcaacctt
    27601 gaccttgtcc tcttgatcta gaagcacatt aaggccgaca gcagatggtg tctgctcaga
    27661 ctctgtcaag tagtaggcca gatcctcacc aatctcaccg gtaatcaagg gtgttgtaga
    27721 ggtgtaggga ttgcctgttc catagtccgt aattgtcaca aagtgtccct gtcccataaa
    27781 aggaccaacc agtacttctc cagttgctgt ttttttgata tcaacaccgg gattttgaat
    27841 atagcccttg acatgccctt ttgtgtcagc aacagaaata atatgcccaa aggaggaatc
    27901 gccaataacc ttgacagtaa ccttactatc tcctttttgg ttggcagcta gaatctgatt
    27961 ggcaatcaag gtacgaccaa gtgcaaccgt tgaagatgat aaggtatgat gcctttcctg
    28021 agcatatcga acagtttcgg tgcaatccaa aacataggcc ctgaaggcac cggaggcaga
    28081 aattgtttta attagtttat ccataatttc tattatagca taatgaacaa ggcttgtgct
    28141 ggttgcttta gaggaaagct gcttgaaaat agagaaacac tatttggtta ataatagcag
    28201 ctctataaag ccacttaaaa acagagcagt gctaacaaat ggtagtattc ttgtccttag
    28261 cacgcagtaa gctaatcacc taagtcagta caatcaaaca agcatcaaaa aacagctccg
    28321 ataggttgat taaaggaaga aatgataaaa gagttatttc gtaatgcttt gctgataatg
    28381 agcaaggtaa tcatgtggtg tcgtatcagt gtactttttg aaggttttca aaaaatgggt
    28441 ggtatcgtag aaataaagga gcttagccac ttctccagct ggtactcctc ttcgtaaaag
    28501 tagcttggct tcttgtactt tttccttcaa aatataggtc tgcaacgaaa tagaagaata
    28561 cattttaaaa acagctcgta aatgtgactc tgagatataa agatgcttag caatatctga
    28621 tacctttaat tttgaataaa ggtgcttatc gacgtaatat aaaatactat tataaatttg
    28681 ctgcttatca gaaacacttt tgttagtcaa tgattctgag aggctaataa tagcagctgc
    28741 tcttatttga agcaccttaa ggagatctgt agctttttca gttaggttca taaaatgctt
    28801 aatgcgctcg tagtttttgg caacatcagt attttcagta aagcttagtt caagcagctt
    28861 aataaaataa ataatagaaa gatttttttc agctcttaat gcgggaatag aagaggagac
    28921 gacatctgat gaagggatac aattgatttc gtgctttaat agctctgtat tacccagctt
    28981 gactaaatca ataatatgat tcaaataatt taagacagct ggcacatgaa atgacggggt
    29041 attttccaat tcgagattag ctataatatg aggatcctcc cagattagct gggcttcctc
    29101 cagtaaatca ttaatgcttt gctggcagct catttcaaag ttggtgtcaa aaaaggcatc
    29161 aacagctatc aaaaggcttc gaatatgaga agcaggaaaa tgaggaatgg tagagatata
    29221 gccaactagc tctttttttg acttatcagg atagcgcttc aagaagctat cggctaattc
    29281 ctccttatag ctatcctgaa agaaagaggt gtaaaaaggc ccaatgaaaa taaacttgtc
    29341 accaatagga aacattagag aggattcctc aagcgttccc tcataacaag tgagctcagt
    29401 attactagga atatctaatg ttttaattaa ttcatagtag gggaatcgac gctcctcgtc
    29461 atcataagcc tgaaggagct caagattttg agaaagcact aaaacaggta attgtgatag
    29521 gttatgcaa
//
LOCUS       DARYLD010000025        29391 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYLD010000025 DARYLD010000000
VERSION     DARYLD010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29391
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(38..1369)
                     /locus_tag="TU651_000960"
     CDS             complement(38..1369)
                     /locus_tag="TU651_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL0896970.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1460..2239)
                     /locus_tag="TU651_000961"
     CDS             complement(1460..2239)
                     /locus_tag="TU651_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL0896971.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2270..2914)
                     /locus_tag="TU651_000962"
     CDS             complement(2270..2914)
                     /locus_tag="TU651_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL0896972.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2920..3570)
                     /locus_tag="TU651_000963"
     CDS             complement(2920..3570)
                     /locus_tag="TU651_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL0896973.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3585..4775)
                     /locus_tag="TU651_000964"
     CDS             complement(3585..4775)
                     /locus_tag="TU651_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL0896974.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4967..5869
                     /locus_tag="TU651_000965"
     CDS             4967..5869
                     /locus_tag="TU651_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0896975.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6766..7908)
                     /locus_tag="TU651_000966"
     CDS             complement(6766..7908)
                     /locus_tag="TU651_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896976.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7905..8768)
                     /locus_tag="TU651_000967"
     CDS             complement(7905..8768)
                     /locus_tag="TU651_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896977.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8779..9105)
                     /locus_tag="TU651_000968"
     CDS             complement(8779..9105)
                     /locus_tag="TU651_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL0896978.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9709..9873)
                     /locus_tag="TU651_000969"
     CDS             complement(9709..9873)
                     /locus_tag="TU651_000969"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0896979.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10112..11008)
                     /gene="era"
                     /locus_tag="TU651_000970"
     CDS             complement(10112..11008)
                     /gene="era"
                     /locus_tag="TU651_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL0896980.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGAFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11144..11545)
                     /locus_tag="TU651_000971"
     CDS             complement(11144..11545)
                     /locus_tag="TU651_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL0896981.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11526..12023)
                     /gene="ybeY"
                     /locus_tag="TU651_000972"
     CDS             complement(11526..12023)
                     /gene="ybeY"
                     /locus_tag="TU651_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL0896982.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12372..12998)
                     /locus_tag="TU651_000973"
     CDS             complement(12372..12998)
                     /locus_tag="TU651_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0896983.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13053..13628)
                     /locus_tag="TU651_000974"
     CDS             complement(13053..13628)
                     /locus_tag="TU651_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL0896984.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQVPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13675..14775)
                     /locus_tag="TU651_000975"
     CDS             complement(13675..14775)
                     /locus_tag="TU651_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL0896985.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14878..15093)
                     /locus_tag="TU651_000976"
     CDS             complement(14878..15093)
                     /locus_tag="TU651_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL0896986.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15090..15599)
                     /gene="msrA"
                     /locus_tag="TU651_000977"
     CDS             complement(15090..15599)
                     /gene="msrA"
                     /locus_tag="TU651_000977"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL0896987.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15937..16794)
                     /gene="cvfB"
                     /locus_tag="TU651_000978"
     CDS             complement(15937..16794)
                     /gene="cvfB"
                     /locus_tag="TU651_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL0896988.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16928..17485)
                     /gene="frr"
                     /locus_tag="TU651_000979"
     CDS             complement(16928..17485)
                     /gene="frr"
                     /locus_tag="TU651_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL0896989.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17522..18250)
                     /locus_tag="TU651_000980"
     CDS             complement(17522..18250)
                     /locus_tag="TU651_000980"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL0896990.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18549..19229)
                     /locus_tag="TU651_000981"
     CDS             complement(18549..19229)
                     /locus_tag="TU651_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896991.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19216..20004)
                     /locus_tag="TU651_000982"
     CDS             complement(19216..20004)
                     /locus_tag="TU651_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0896992.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19992..20798)
                     /locus_tag="TU651_000983"
     CDS             complement(19992..20798)
                     /locus_tag="TU651_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896993.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20783..21724)
                     /locus_tag="TU651_000984"
     CDS             complement(20783..21724)
                     /locus_tag="TU651_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0896994.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21802..23424)
                     /gene="nikA"
                     /locus_tag="TU651_000985"
     CDS             complement(21802..23424)
                     /gene="nikA"
                     /locus_tag="TU651_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL0896995.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            23926..25566
                     /locus_tag="TU651_000986"
     CDS             23926..25566
                     /locus_tag="TU651_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0896996.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGEKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(25810..26499)
                     /gene="rplA"
                     /locus_tag="TU651_000987"
     CDS             complement(25810..26499)
                     /gene="rplA"
                     /locus_tag="TU651_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL0896997.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(26605..27030)
                     /gene="rplK"
                     /locus_tag="TU651_000988"
     CDS             complement(26605..27030)
                     /gene="rplK"
                     /locus_tag="TU651_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL0896998.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            27266..28063
                     /locus_tag="TU651_000989"
     CDS             27266..28063
                     /locus_tag="TU651_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0896999.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            28218..28568
                     /locus_tag="TU651_000990"
     CDS             28218..28568
                     /locus_tag="TU651_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL0897000.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(28897..>29391)
                     /locus_tag="TU651_000991"
     CDS             complement(28897..>29391)
                     /locus_tag="TU651_000991"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897001.1"
                     /translation="KRIFFFSVVALTILTISDQKVNASQYRWRQYYYRMSPTERELKK
                     EKEVLRNFIATIKLSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEI
                     VSSLIDEHFPEGHSRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKL
                     WYIQ"
BASE COUNT         9086 a         6792 c         5225 g         8288 t
ORIGIN      
        1 ctaatagacc aatggttttc cattgatcta ctgtgtatta aaaaaacagg ctagttaaca
       61 taataatgct ctcggccacc aacgtaccac caaaaactgt aataaaggtt tgtttaaagc
      121 catttttatg gctgagacca gtaaggctca agaaggttaa aaagacgcca gactggggta
      181 caatggtcaa aatattagag gcaacagctg ccacacgatg aatgatctca ggtgaaacgc
      241 ctgcatctaa ataatattga gcaaaatttg gcattacgat ccctaacgct cctgaagacg
      301 aacctgtaat agctgccata gccgaagtca ggacagtcaa gctgatcaca ggtggcccag
      361 gaatattcaa aatgatgtct gagaatacgc caaaaccaga tgctgctgta acaacagaac
      421 caaaggctac tgcagaggct gtcgcaaaga ttggaccaac cgcaccgcta gcaccaatgc
      481 tgagggtcgc aattttctta tcaatgtact tgttaaataa aacgatagct gaaataattc
      541 ctgtcaagag ggccacataa atgatatttt tcttaacgaa ttcgtcccct agcagactac
      601 ctatgatggc aataacaatc aagagtatca aaggcaagat gctgactaca aatggtggta
      661 aaaccctttc agttgtatct tcatttgttt gactagtata ggtcgcatag ttttcgccaa
      721 cttctaaact cttagtcaaa caacgcttca tatagaaaag accaaaggcg atacagccaa
      781 cactccctaa aatacttggc accaaggctg cggttagaga cgtgttaaga tattgtatag
      841 ggataacgtt ttgaatcgct ggtgtaccag gtaagatcgt catagtaaag gttgcaatcc
      901 ccaaccaaag tggtacttga attaagttcc atgctaagtc catcttttta aagagagagc
      961 gtgccaaggg tagaacagca aacatgacca caaagagact aataccacca taagtcaaaa
     1021 tagcactgat gataaaaata gccaccaaga tacggtaagg gttttgataa cctacttttt
     1081 tcaagataaa ttcagcaatg gaaactgttg caccactgac ttccatcaat ttagctaaaa
     1141 tagaccccaa caagaagata gcaaagtagc tcatgatata gccacccagc gcacccatat
     1201 agttatttgg ttccttaccc aagagtgact caactagtgg catactattt agaaggacga
     1261 ccaaaatcgt tgccatagga gccgcaatgg taatatgaat ttcctttaga gaaaaataaa
     1321 cgatggcaat aatgcccagc aagaccccaa ttggtcctaa aaattccata gtgtttctcc
     1381 tctcacattc agaaggagca agagatagag aaatgtcact ctatctccaa tcctcttatt
     1441 tacactgaac ggacagctct tactgagcag tgtagccacc atccaagata accggttgtc
     1501 cagtaattcc ctttgcctta tcacttgcta ggaaggagac ataatctgca atttcttgta
     1561 cgtcaatcaa acgtttttgc ggtaccaacg ggtacaacac ttcttccaat acattttcaa
     1621 gcggaatctt acgtgtctta gagaggtctt caaattggcc acgaacgagt ggtgtgtcca
     1681 catagcctgg acagatagcg ttgactgtga tacctaattc tgcggcttca agcgctgcaa
     1741 cctttgtcaa gccaatcaaa ccgtgttttg ctgaattgta agccgctttt ccggcaaaac
     1801 caatgacacc attgatagaa gccatattaa tgacacgacc aaagccttgc tttttcatag
     1861 ttggaaaagc gcgcttaata gcgataaatg gcgctgtcaa catgaccttc aacataaatt
     1921 catattttgc tgttggaaaa tcttcaatca tggcaacatg ctgcaaacct gcgttgttga
     1981 ccaaaatatc caaacgacca tgcttttcaa ctgtataatc aatcgcttta ttgatcgctt
     2041 cttcatttgt cacatcacac aaaacagaat cagccgccca gccttttgtg gtatactcat
     2101 caacaacagc atctaatttt tcttgattga tatctgaaaa gacaacgatt ttgccctctt
     2161 ttaagaatgt ttcaccaatt tgtttaccaa taccgcttgc tgcacctgtt acgaatacta
     2221 cttgtttaga catatttatt tcctcacttt ttttaaatat tgttttctat cagttatgat
     2281 aaattaatct tgcttcggtg gcttcttgaa cttcttcaaa ggtataatct ggatgaattt
     2341 cttctactgc gattccctct ggagtgactg tgaagacacc catttctgtg acaatcttgt
     2401 caacaactcc tgctgctgtc aatggcaatg aacactcctt caagattttc catttgcctt
     2461 tattggtatg ctccatagca acaatgactt ttttagcacc gactagtaaa tccatggcac
     2521 cgcccattcc tggaaccatt ttccctggaa taagatagtt tgcgatgttt cctttttcat
     2581 caatttgcaa agcgccaaga actgttgcat cgacgtggcc accacgaatg atcccaaatg
     2641 aagtggtgct atcaaaaaat gctccgcctg gtacgatgcc aaccggctga ccacctgcat
     2701 taactatagt tggatcaatg tcatcgccta ctttatctaa gccgacaaaa ccattctcag
     2761 actgcagcat gatagtcaca ccttctggta aaaatctagc taccttggtt ggcaagccaa
     2821 tccccaaatt gaccagggaa ttatttggaa gctcgagtgc cacacgttta gcaattcgtt
     2881 cttgaatttc ttctttgctt aattctttca ccataacgct cattctcctt ccactagata
     2941 attgacaaat atgcctggtg tttgaactgc aatgggttca atgtctccaa gcgagacaat
     3001 ttcacgcgct tcaacgatgg tcacttttgc atttgctgcc ataacctggt tgaaattatt
     3061 ttcagagccc ttgtagcata ggtttcctaa ttcatcagcc ttatctgcaa aaattaaagc
     3121 gacgtcagct ttcaatggta attctaacag ataatccttg tcattgacct gtaatttttg
     3181 cttaccttcc tctaccaagg taccgatgcc tgtcggagtc aagaagccac ccagtccgta
     3241 agctcctgct cggattcttt cagccaaggt tccttgtggc actaagtcaa tcactgtttc
     3301 accggctgtc atttggcggc ctgcttcttt gttcaagcca atatgagaag cgataatttt
     3361 ccgaaaccga tgttgtgcta ccattttacc gacacccttg tctgggaagc ctgcatcgtt
     3421 acaaataaga gttaaatttg taactccttt tgctaccaaa gcgtcaatca ggcgctctgg
     3481 actcccgtta gtcataaaac caccaaccat gatggtgtcg ccatccttta caaggttaac
     3541 agcttcttct atgctaattc gtttattcat gaaaccatct ccttttattt ttcaatcaat
     3601 acagacgtcc cttgaccgcc accgatacag agtgttgcca atcctttatg tgcctgacgc
     3661 ttttccatct cgtgcaatag tgtgaccaag atacgcgcac cgctagcacc gatcggatga
     3721 ccaagagcaa tagcaccacc attgacattg acgatagccg cattaagacc aagctcatct
     3781 acaacactga tagcttgtga ggcaaaggct tcattggcct ccaccaaatc caagtcttca
     3841 attgtccaac caaccttagc aagggccttc tgagtggaag gaattggccc agtacccatg
     3901 acctctggtg ctacaccagc acttgcataa cctttaatgg ctcccagaat tggaagacca
     3961 agttcttcag ctttgtcacg actcatgaga aggacagctg ccgcaccgtc attaattcct
     4021 gaagcgtttc ctgcagtaac agttcctgaa ccatctcgga caaaggccgg acaaagggct
     4081 gttaattttt caagggttgt tccagcttta atgtactcat cttctgccac caaaattgga
     4141 tcacctttac gttgcggtac tggcactgga ataatctcat ctacaaagcg accagcggcc
     4201 tgcgcagcag cagctttttc ctgactagcc aaagcaaata tatcttgagc tttacggcta
     4261 atcccatagt tttttgcgat attttctgct gtaattccca tgtggtaatc atgaaaggca
     4321 tctgtcaaac catcattgac catagtatca atgatttttc catcgcctaa gcgaccaccc
     4381 caacggtaat ctttgagcac atagctggct tggctcatat tttctgtccc acctgcaata
     4441 atgatatctg aatcaccaca gacgatactt tgtgctgcta actcgatgga tttgagacca
     4501 gaaccacaga ccatatccac agtgaaggca ggtttgtcgt ttggaatacc tgcagttatc
     4561 cctacctgtc tagcaacatt ttgaccgagt cctgcatgga ggacatttcc gaaaatgacc
     4621 tcgtcaattt gttcaggctt cacacctgat ttctctagta atgcttctac aaccactttt
     4681 cctaattgaa cagccgagac agatttaaag gctccaccaa atgaaccaat gggtgtccta
     4741 acagctgtag tgataacaac ttctttaacc aacatgcgat tctccaatct atttgttata
     4801 gaaagcgctt tctgtttttg tgaatttatt ttatcactac taaaagcgtt tgcaaaattc
     4861 gattttttta tatgactata aaaaattttt attatttttt attgacagct ataaaaatta
     4921 ttattagtat gaagaaaaag acatctgaaa tgaaagaaga ggcaatatgg atattaaaca
     4981 tttacgcttt ttcattgcta ttgtagaaaa taattttaac ctgagccgta ccgctcaaca
     5041 gctttatatt tcccagccta ccctcagtat tatgattaat gattttgaag aaaagcaggg
     5101 cattaagctc ttcaataaaa aatacaataa aatcctcggc ttaaccatga caggcaagca
     5161 attttatgag gattctttgg aggttatccg caaatatgac aagatgcacc aaaatctctt
     5221 ttccaccaat caaaagttgg acggtaatat cactatcggc attcctccat taattctgtc
     5281 aattgttttt tcaaaaatca tgccagaaat tattctagaa aatcccaata tccactttaa
     5341 tattaaggag tatggtgcta atcggctacg tcaggaattg attttagaga atgtggatat
     5401 cgccattctt ctgcatcctg aacgaattgc tgcaaacacc attgattctt tccaaatcca
     5461 agaatctgag ctctgtgcat ttgtctccaa gaaccaccat ttggccaata aaaaaatcct
     5521 gacttggata gaactccaca atgaaaaact agctatattt gataaaacct tcatgattca
     5581 ccatctcatc aaggaaaaat gtaagtatac tgacattaac ccccaaatca ttctggaatc
     5641 agcttcttgg gactttctga tcaattctac tcgtatcaac cctcaactaa tgacgattat
     5701 tccaaaacca acggtagata gctatggttt tcaggatatt gtggctattc ctatggagaa
     5761 tcctattcct tggaaagtca tggttagtcg tctcaaaaaa gatcattatt ccaccataga
     5821 agaatacatt ttcaacaaaa tgcttgaaaa atttcatgta atcgaataga gactaacaag
     5881 tgatcccttt cacatgactg cacgtgccct tcgacatatg gcacctcaac taacccttag
     5941 cgcatatgga aacagctcaa ttctttttga aggataaaac taaagaggct tgacgatcca
     6001 tactaactca gacccaatat tattatcaag atcctaaata ttaacacaac tcatttataa
     6061 caattaactt acaaaaaatg gtctactcct ttgaggcgtg acagcaatac tgcaatttat
     6121 aaaaaatgac tgtcaagaca atatctctga actcagtcac tgtttctcaa aaatcactca
     6181 catctaatgg agtactatca agaaaaagtt atttttaaaa tcatcaataa cctatctaaa
     6241 ttttctaaac aatgccatat aaaaagagct ggagtcacca agctctaatt gatttttaca
     6301 tgatgctcta taacaatatc gtttaaagat cattcttttt tactagtatg ttgatcacat
     6361 tttctaaaag ccagaaagag acttgaatac cgagtccctt ttctttttat ctataaacag
     6421 ccttaaagaa gcccagacag gctgcggtaa ttttcttaac atgagcttct actatttctc
     6481 ttgttaagcc ctgctcactt gatgattcgt tatttttacc acctgaagac tctcctctac
     6541 ataggctact ttgtcatcta gttcctgctt cttaacgata tatcatcgtc tcaattgatg
     6601 ccacttccct tatcatctta gaaaaaagct aatttctata cctttaggtg ttctagatca
     6661 caaaatagct ttctcaatcc tatctacctt gcaagaattc attgaatgcc cttaactttt
     6721 gcagtaacga caataaaaat agtttagata acgatgctat tgatgttact gacttaccct
     6781 ctttattgat aagtatgcta aatataagca aagaaatgca aaagctaatc taatcatgac
     6841 aataactaat ccatcaaccc aaaaactgcc aaaaaagccg tcataagcaa gcttaagcat
     6901 tatgtttggt gtactcgcag ttgatacaga taaaatactc aacaccttat gaggtattcc
     6961 tgcttggaaa atatccataa gaaaacttgg tacaaaaaca ctagccgcag acaaggcaaa
     7021 acctgtcaat ggagacttaa ccttacttga aataaggata gtgatagccg taatcaggat
     7081 aagcccaata aactgatagg tgactagatt gataaatgtt cccaaaagag tcattttttc
     7141 tggaaaagcc attatattca cattgctgtt aatccaatac agattgagtt gaacactcgt
     7201 gtcccaacca cttaatccaa aataccaaac aaagaccgct aatattatgg cgtaaaaagt
     7261 aacaaacact gaggtgctta tcaagtaact acttattatc ttggctatcg taagtttatt
     7321 acgaccatac ctagttgtca ataaaatagg attcatattt ttagcagtat caccggaaaa
     7381 aacaggagcg atgaagtaaa cagacaaaag aagaagaagg atataagcac tatttatgac
     7441 cagaaaaagc tgattccagg gtgcaaaatt acccaacttc agctctttaa agggaagata
     7501 agagccaaga gccgtttgag attttggggt gatcttactg aaatcaatag tctcttcttt
     7561 tttcaaatta aaataataat ctctaaattt tggatcaaaa tggctagtta catagtagcc
     7621 atacacattg aagacaggat tttttgagct gccacctaga gtataatctt tgattgttct
     7681 aattaataac tcattggaca attgaccggt atgttcttcc gcaaatcgct tgtttatctc
     7741 aacagcatct cttccatgaa ttttatctat cgaagaacca ctgatttgtc cattaaaaaa
     7801 gttgatataa aataacccaa agattgctaa taagctaaca ataaacattc ccaaaactga
     7861 tttggttcgg atcagttttt ttaattcaaa tggtaagaga gctttcataa cacctgttcc
     7921 tctctaaagt gataaatgta taagtcttct aaggttggtg acactagttg agccaactga
     7981 tttggtttct catcactaac cacacgaaaa acacgactag atgaaactag tttctcattg
     8041 actacagcat actgaccatg ccttggtaac ggcgaaccat cagagacaga aaactcccag
     8101 accttgccaa agatggtttt caacaattct tgactactac tcttatggat aaattgacca
     8161 ttttttaaaa tgataatctc cttagcaata gcctcaacat cagagacaat atgagttgat
     8221 aagataataa ttttgttggc cgacaattcg ctaataatat tgcgaaactt caccctttct
     8281 tttgggtcta atccaactgt cggctcatct aaaatcaaga ttttagggtc attgagtaag
     8341 gcctgggcaa taccgagacg ttgcttcata ccaccagaat aagaggcaat ccgcttcaga
     8401 cggacatcat atagatccac aagttttaac aattcatccg tttcttgctt ggctttatgt
     8461 ttaggtattc cttttaaggc tgccatataa agaagaaagt ctcgaccaga aaaacgacca
     8521 taataactaa actgttgagg caaaaaacca atatgctgat aaaattcctc tgattgaggt
     8581 ttgtgatcca gtaaaatctc tccttcatca ggagtcgtaa aatgactaat gagattgagc
     8641 aaggtcgttt tccccgtccc attagcccct aaaagtccgt aaaggcctgg ggtgaattga
     8701 gtagtaatcc ttcgcaaaat atttttcgat ccgtagctct tactcaattg atttaattct
     8761 aataacatag aaccctcctt aaatgagtct actgagcacc tgtaactcag tactcagtag
     8821 acttctcctg tacgaaatcc tgctgtctgt aacctttatt attctcgtag cataatcaaa
     8881 tccagagatt ttcgattcat taatgaaata ttgacgatga caccttttta atttcccagc
     8941 actttctccc tcaatctgtc tcagtgacgt agctgcccca aattcccctt ttagggtaac
     9001 aaatactact gtgtgaggct tagatgaatg tgttgtcaca tcataggttt cagagattgg
     9061 taatttaaca actgacctat tcttatataa aataacatat ttcattgacg tcctccttct
     9121 ctatttatat cttaatacaa gtacaagcat tgagacggta aagtctcaaa tggtatctat
     9181 catatcctga atggtatcac agtagctgtt taagatgtca tagaggcatt tgagaaatgt
     9241 aacctgtttt cctttcgttt tttgatcata tgatattgta ttagttcgga gaaccatggt
     9301 aatcattcaa atcttacata aacctctctt gggatatggt attagcgtct atattaatta
     9361 ctacttcaac agacaccttt ttaaagctgc taaaattgtc agtggcaaac aaataggcta
     9421 taggtataaa tctcacactt attttatcat aaaatcattc tttttatcat ctaatcaaat
     9481 gtacaagcac tttaaagtta ttctcatgac tctattattc ttattggaag ccatattaat
     9541 tacgacgaca ttttcagaaa tcattatcgt gtgtttggta tcatcgacac aaccgctaat
     9601 aaatcgttta aatgtatcca aaaccaaatt catgattacc tgttcaaaga ataaccagag
     9661 ggcttactga ttgctttaac aaatatttct agtcttctca ttttgtactc atataaactc
     9721 atctactcta ttaaaaattg ctgtgaacag aaaaaccttc tcaacctgtt tcagttttat
     9781 agccgtagtt agtttaaagt gaaaccaccc tgcattttct atacctaaat ccaattgact
     9841 tgctttttca gcatcaacag tcatgctatc cataagataa cacaccacga tgtgttgtga
     9901 ttattgttct tctatattta gccttacctc ctgaaaacaa aaaaagagaa caccttttaa
     9961 atgttctcat ataagcaatc ttatatatta aatgaggatt cgatctaatg acaagacagc
    10021 cttattgcta ccaataatgc agcttaccaa acaagggcaa tcagtataag ggttgctaac
    10081 cagctctgct gacatagcct gctttgagcg atcaatactc cttctgatta tagccaaagt
    10141 cagctaaatc aagctttttg tcacgccagt ttttcttaac cttgacccag gtctccagat
    10201 agaccttatc gcctagcatt agctcaatat cacgccttgc cagcttaccg atttttttga
    10261 gcatggcgcc ttgttttcca ataataatgc ctttttggct gtcacgctct accatgatgg
    10321 taactcggat atgcaccttg tcagtcacct catcacgctt catcgaatcg accacaacag
    10381 caactgaatg aggcacctcc tgctgtgtca agtgaagcac cttttcacga accatctcag
    10441 aaacaagaaa gcgctctggg tgatcagtga tttgatcctc tgggaaatac tggaagccct
    10501 cttcaaggtt atcctttaag agctgaacga gcgtttcgac gttgtttcct tgaagtgctg
    10561 aaataggaac aatttcctta aagtccatct gactacggaa atcatcaatc tgctccaata
    10621 attggtctgg gtgaaccttg tcaattttgt tgatcaccaa aataaccgga atacgagcag
    10681 ccttgaggcg ttcgataatc atatcatcac ccttaccacg cttttcatca gcaggcacca
    10741 taaaaagaac cgtctcaacc tcacgcaggg tactataggc tgattccacc ataaaagcac
    10801 ctaaggctgt cttaggctta tgaatgcctg gcgtgtcaat aaaaacaatt tgctctgtct
    10861 ctgtggtata gattcccata attttattac gggttgtctg cgccttatcg ctcataacgg
    10921 cgattttttg tcccatgaca tgattcaaaa acgttgattt gccgacattt ggtcggccaa
    10981 gaatggcaac aaagcctgat ttaaacataa gctactaagg gcctaaagga tcagtcaagg
    11041 taagaatcaa gcagcaggct attcacctga ttgctttcct aaagcttata ctcctttcct
    11101 gcgctgcact atcgcacagg atagcccatt tcctttcatt tttttaatgg cataacattc
    11161 gccaaatttt gggaacaaag ataatcagcc ccgtcaaaac agcatagcct gaaatgacca
    11221 ggacagcacc tgcagccata tccttggcat gcttagccag catggagaaa tggtaatcac
    11281 ttgccaagtc aaccacattt tcaatagctg aattgacaat ctctaaggta atcaccaaaa
    11341 aaatagccag caataaaaac agccattcta tagcagaaat accaaaaaca atcccagcca
    11401 aagaggctaa cagggctgac aaaagatgac ttcttaggtt acgctcctcc ttaaaggctg
    11461 tcagaacccc tgtcaaagca aattctaagc tggcaattac tgttctgttt ttccatttgc
    11521 gtttattatt gtcttgtgag gccataagca gtcaaaatct cttcctgtaa cgtaaacatc
    11581 tctttttctt cctcaggagt gtaatgatca taaccattaa tatgcaaaaa accatgaaca
    11641 gccaagaagc ccatctcacg ctcaaaggaa tgcccatagg cttctgcctg ctcatgggct
    11701 ttgtcaacag aaataaacag ctccccaata taagcatcaa actcctgtat catacctgcc
    11761 aagtcaggat caagctccaa atcctcttgg ctaaaggcga tcggaagctc tggcttgtac
    11821 tccagagaaa tcacatcagt cggacgatca gtatcacgat attcaagatt caaggcgtgg
    11881 cttctatcat tggtcacaaa ggtaaccgcc atttccttgt cctctttacc aattgttttg
    11941 gcagcaaaat tgagcaaatc aatggtttgc tccatcatct cttgagaaac ctgcttagtt
    12001 tcatcaatca tctctatata catcattata tgaagaggtc ctagcaagac aggtccaaac
    12061 aaacaccaca ctgctaggtc aaaaagcttg atacctctta tcctttcaac atcatttcag
    12121 tactttcttt ccattatacc acaagaaaaa agaaaaagca ggcattagtc tagcctgctc
    12181 caaaagaagc cggaataatg acaagatcgt tgatacccca gcagctgctg tttctggaat
    12241 acccagagcc tgctgcgcag aatacagtcc tcttagatag ctgggactcc taggattaca
    12301 atagtagata agcctttaga ccacttccat cgcctaaaaa ctaatcctaa acggctttcc
    12361 cttagatacc actagctgct ctcaaagcta ttgtggaggt aacgatctgg cttattggct
    12421 gacgccagtg atttctgctt gtcataatct tctttggtta aataatagtg cagcactgtc
    12481 acaaaacggt tggaatcaag gtgatcacgc ttagcatatg gctcttcatg tgaaaagcac
    12541 atgccgcttt tagccataac acgtcccaaa gccggattgg ctttatcatg cttagcaatc
    12601 acacaattca tgcctaaagc ttcaaaacac aagaccagta cagccttgac agcctctgtc
    12661 gcatagcctc ttccccagtg atgcttatga agacaatagc caatctcagc tctacctaaa
    12721 tccagctgta tatgatgaag atcaagcgtc ccaataaagt ctcctgtttc ctttaacaca
    12781 atcccccacc gtccaagtgg actagccaga tagacagaag caatgacttg acgggtctcc
    12841 tcaattgtct gattggctgg aaagctatac ctgacagtct cttcatcaga agcataatca
    12901 aacatggctt tggcatcatc caaggtcact ggacgcaggc atagacgctc tgtctcaaga
    12961 tacctatgct ctgctagttt ttcaaaaaag cttgccacta ctactctccc tttcctaaaa
    13021 atctaactca cctaacagca tgactgcctg ccctagccgc gtaaaatctg cctcacctta
    13081 tcctttaaaa caggaaccag ctcctcttca aaccaagcat ttttagccaa ccaaagctga
    13141 tttctaggag atgggtgaac aaggggaaaa taatccggaa gatagtcctc aaaatgctgc
    13201 accgtttcgg taagattgcg tctacaacct tcaccaaggt aatattgctg ggcatactgt
    13261 ccgaccagca ccaccaattc aacctgaggc atcaaggcca ttaacggacc atgccacttg
    13321 gcagcaaagc cctttcgcgg tggtaaatca cctgattttc ccttaccggg ataataaaaa
    13381 tccataggaa gaacgccaaa caagcccgac tgataaaagg tcctgtcatc aacacccagc
    13441 caagctctca agcgaactcc gctacgatca ttccagtaca gacgcgtctc ctgagctaca
    13501 ataccaggca cctgaccaac aatgactatc cgagcggtct gaggagctgc ataaagtggt
    13561 tcgatacctt ttttggtata gtcacgattg gcaggatcag ccataatcgc ttgcaatagc
    13621 tctgtcatga taccctcact ttcataaaag gctcttcagg tgaagagctc ttttttacga
    13681 tttgtcttct ttaggcagct ctccaatgac ctcataggtt gttaagcctg acgtagactg
    13741 acccgtctct gttttaggcc gatctggagc cttagtctga tgttgcagct gattagggct
    13801 gctttttaat gactctgctt ttgaacctac agtttcatag gccttaataa tctcagcaac
    13861 aacagggtga cgcaccacgt ccttggctga aaaatgcaca aaatcaatct gcttgatggc
    13921 ctgcaatttt tgagctgcat caatcaagcc tgatgtgata tgacgcggca aatcaatctg
    13981 actaatgtcc ccattaacaa tcattttaga ctgaaaacca agtctggtta aaaacatctt
    14041 catctgcatg atggtcgtgt tttgcgcctc atctaaaatc acaaaggcat catctaaggt
    14101 ccgaccacgc atataagcca agggagcaat ctcaataata tcacgctcca ttaaccgagt
    14161 agtctgctct ttaccaagaa tctgataaag ggcatcgtag actggtctaa ggtaaggatc
    14221 aaccttttcc ttcaaatccc ctggtaaaaa gcctaagctt tctcctgctt caacagctgg
    14281 gcgtgtgaga atgatccgct taacctgacc acgctttaaa gcagtaactg ctagcgtaac
    14341 tgctaaaaag gtctttcctg ttccagccgg accaatacca aataccacat catgatgctt
    14401 gatactatca acataggcct tttgccctag cgtcttaaca cgaattggct tgctataaaa
    14461 gtccttgata atctcttcct cataaagagc aacaaattga tcaagcctat ctgaatccgc
    14521 catagacagc gcagtcacca catcagaggt attgataacc atgccacgcc ccaccaaaac
    14581 taaaagggct tgtatcgtca aacgcgctag ctcaacagcc cgctcatcat caccaataat
    14641 ctgaactcgc tcagttctag catgaatcac aacattgagg tgagattcta tcatcttcaa
    14701 atggcgctca ttgctaccaa aaagagctaa cagatcatct gggtgattca agctaatgtc
    14761 agtcgaataa tgcaaatttg tcttcctttt ccatctataa gtaactctat tataacaaat
    14821 tttgctataa atcgggaata agacccagct ttaaagccta aaagagctag cctatggcta
    14881 gtggctaagg taatcctccc aaatctggtc aaactgcccc agattgaatg aaaagctcgc
    14941 ttcctcttca aggtaacgac tgatggtctc aaaatcatct gtatgctttg gaaaggtcgg
    15001 gtcctcaaaa accaaatcag ctaataaagc agcaggctta ttagatgtcg agttgcgctg
    15061 agccatcagc caagtgtaaa acgcctttct cattgccaat gctcctccaa aaattgatga
    15121 cgaatagcac tactttgtgc ataacgctct ggattctttt gataaaagcc ctgatgatag
    15181 tcctctgcta gataaaaagg ctctgccggt tcaatgcttg tcacaatggg ctggtcaaag
    15241 cgccctgagg cctgcagggt ctgcttggac cgctctgcaa tttcccgctg ccgctcatca
    15301 gtatagtaaa tcaccggccg atagttgtct cctctatcct caaattgccc aaaggcatcg
    15361 gtcgggtctg tctgagccca gtaaagctct accaaatctg aatagctgat cagactcgga
    15421 tcaaagataa tctcaacagc ttcagtatgg cctgtcgtct ttgagcaaac ctgctcatag
    15481 cttggattgt gaacatgccc tcctgtgtag ccacttctca ctgataaaat acctgcctgc
    15541 tcctcaaaag gctgcaccat acaccaaaaa cagcctcctg caaaaattgc tctttccata
    15601 cctaatctcc actttctttg tccttacatt agtgattttc attgtaacaa aaaaccttgc
    15661 cagaggcaaa gcttaatata aaacaagtca cagactcaaa gtaacaagac tcctcagccc
    15721 aactagtgcc tagcactaag cagtactgtc aagcagccac tactagatca agagggccac
    15781 acagagcttt ttcgacaaca aaaatgattg gcgctttaaa acaggctatc agctaagctc
    15841 cacactcaaa ataaggaagc tagctatact gataaaggat aagtcttagc aacaccgatc
    15901 cagcttatga ttataggcta agagacagac agctccctat gatatcagct cagttcctgt
    15961 cacgtcctgc ttgatcttgt tagccttcat caaaccacct aaggcctttt taaattgacc
    16021 cttggaaatc ccaaaggttg ccttgatatc ctctgggctt gacttatcat taagagtcat
    16081 gtagccacca ttagacttga gataggtcag aatcatctgg gcatcgtttt ccagcatttc
    16141 aaaggaacgc ggctttagcg aaaggttgag ggtacggtca cgttctctaa agccaatcac
    16201 ccgagcggtc aaaacctgcc ccaaacgagg ctccgtataa cgctcgctag ggtggataaa
    16261 gcccagcata ttattttctg gcaggtaaac aaaggtccct gatagcttca agcgatagac
    16321 aatagcaggc aggctttgat tttgcatgtt atcataggct ggactagcaa gcctttgaaa
    16381 tatctctggc tcagctggca aaccccagat acgatctttt ttgtcaacca caagcttaag
    16441 ataaagcctg tctccttttt taggccaaag atcctttagc tccggcaaaa catctaagga
    16501 aaccacaatc tccttatctg gaataccagt atcaacaaac accccaagat cacgacggac
    16561 agtggtcacc tcgccccagc cataatgatc acgccttgcg tcaataggct tcgtggtcaa
    16621 gcgtagtctt tgcttcatat ctgtatagac aaagccctta accatatctc ctaatctatg
    16681 actgccttcc tccttagcta gagcaaagct cagcccctcc ttttggacaa gataaaactg
    16741 actattttct tcttttacta agccagtgat aactgttgct aataaatgat tcatatcttt
    16801 ttgttctttc ttttaaaaaa tagggacaag tccaaagcag ctgcttttta gccttgtcac
    16861 ctatcctgtt atgcctgatg tgtattaggt tacgcagctg atctagctta atgatcagat
    16921 aagccgctta aactgaaagt aattcctttt ctttgtcagc agtcattcgg tcaatctctt
    16981 tgacagcctc atctgttgct ttttgaatat ccttttccaa ggcttttaac tcatcttcag
    17041 tgatttcctt agccttctcc tgctttttag cctcgtccat agcatcacga cgaatattgc
    17101 gaatcgaaac cttcgcagtc tcaccaacct ttttcacttc cttggctaat tccttacgtg
    17161 tttcttctgt aagcgctgga ataaccaagc ggatgacaga gccatcgtta gctggtgtaa
    17221 tgcccaaatc agaagcattc aaggcacgct caatatcctt gattgatgat ttgtcaaatg
    17281 gtgaaatcaa aagcacacgc gcctctggta ctgtaataga agccaattgg ttcaacggcg
    17341 ttggtgcacc ataataatcc acctgaatac gatccaaaag gctagcatta gcacgacctg
    17401 cacgaatgct tgcatactcg cgtgctagtg agtgatgtga ctgtgtaaaa cgttctttcg
    17461 cagtttcaat aattgcattt gccatgattg tttttctcct taatccttta gctctaaaat
    17521 cctaatcgca ggccttattt gataccgttg tgccaatatg ctctccaaag accacacgct
    17581 tgatatttcc tgcttcattc atattaaaga caaccaaatc aatatcatta tccattgaca
    17641 aggttgaagc tgtcgcgtcc ataatcttga gaccgcgctt gataacctcc ccatgagtca
    17701 attcatcaaa cttaacagcg tttgcgtcct ttcttgggtc agcattgtag acaccatcaa
    17761 caccattttt agccatcaag atagcatctg cctcaatctc agcagcacgt aaggccgctg
    17821 tcgtatctgt tgaaaaataa ggtgacccaa taccagcacc gaaaacaaca atgcgcccct
    17881 tttccagatg acgaagcgca cgacctcgaa tataaggctc tgcaacgttt tgcatgggaa
    17941 tagctgtctg cacacgagta tcaacgccat aatgctgaag gctatcagcc attactagag
    18001 cattcataac ggttccaagc atgcctgtgt aatcagcctg cacacgatcc ataccagcct
    18061 ctgcagcagg ctcaccgcgc cagagattac caccaccaat aacaagagca atttcaacac
    18121 ctgaattgtg aacttctgcg atctctttag caatcgactg aaccgttgtt atgtcaatgc
    18181 caacaccctt atcaccagcc aaggcctcgc cagacaattt gattaaaata cgttgatatt
    18241 taggtttcac tatttatgat ctccttattt tgtccctacc attctaccac aaaacaaaaa
    18301 aatttaatag accaatgcaa gagaggaaag cgaaattttt gacgatcctt ttatcaagat
    18361 ccctttgagc agcaaaaaag atgagtcatt ataaaaagag cattatcgta tccgaatagc
    18421 acagttataa cctattaata cgacaaaaac cagaacaact atgacaaaaa acgccgtaaa
    18481 aaagacttaa aatcaagcct caagccagac tagattctaa gtcgtgctat attgagagat
    18541 gatttgtttt agttatctag cccaatgccg ccacaagaag tctgaggctc cttatctctg
    18601 acagcaacta gcctcccctg ctccagcagc agaacacgat gacaaatggc ctgacagata
    18661 ttagcatcat gcgcaataaa aatataagtc agttgatact cctgctttaa ctcatagagc
    18721 aagtccaata gctgcccttg ggtaataggg tccaagccac tcaaagcctc atcaaaaatg
    18781 atcacctccg gccttaacaa aagagctctc gctatacaaa cacgctgtag ctgaccacca
    18841 ctcagctctc tggccttttt acccagatga gtggcgtcaa gaccgaccgc agctagtatt
    18901 tgaacaacct cctctaaggc aaagtcctta gaaagggcct ctgtcaatat ctcttgaata
    18961 gtaaagaggg gattgactga tcttagcgca tcctgaaaga caagtaaaat ccgaggtcca
    19021 catactttta cagaataggg ctgaccatga aagagcacct gaccagctgt cggctgctct
    19081 agcccaatga ttaacctagc aagcgttgtc ttgccactac cactttctcc cataatccca
    19141 aggctctcac ccttttccat ttgaaaatga caatctgtta gcactggctt ttgatgaaag
    19201 ctcttataaa catgtctaaa ctctatcata gcgtatcagc cgatcataat gattttgcaa
    19261 aagcaactcc ttggtggcag cctgacttgg ccgatgaaaa atcgactcaa cacttccctg
    19321 ttcgatgatt tttcccttac tcatcaccag tagttgccct cccaaagtct gtgccaattg
    19381 gtaatcatgc gtcactgtaa taatggtttt tcccttgtcc tgcaataact tcagcatccg
    19441 tatgatatta gaacgattgg catcatctaa agcagaggta ggctcatcta aaatgataat
    19501 ctgtgggtct aagcacaaca aaatagctag cattacccgc tgtagcatac caccacttag
    19561 ctcaaagggg tacttcctca gcagctcctc tggctgctct agatagagct ctcgcatgaa
    19621 aggcagagcc ctttttagac aggccctttt tgaaagtctc tcatggcttc ggatggtttc
    19681 aaggagatga gcctcaatgg tctgaaaggg attgaacatc gccataggat tttggaccat
    19741 ataggccatg tggcgccctc taatgctctg ccattgctta gcatctaatt gatctagtct
    19801 catatcttga caggtaatcc tccctgtcat ctgtacattc gacgggcatt gaccaattaa
    19861 tagcttagtc aagagggtct tgcccgaacc actcctgcca acaatcacca aggagctccc
    19921 caagggcaac tcaagattga gcttacttaa tagcacatca gagccattat aagccgataa
    19981 atcattaaca attaaccgtt ccatgttttc ctccacccct tagcatcagc gtaatcacct
    20041 aggctgttaa aagctagcac agtcactaaa atggcaagcc ctggtgacat catgagccac
    20101 agagctgtcc taaaatagct ccttgcatca tgcagcatca ttccccattc tgtcacattg
    20161 ggctgaacac cgatacccaa aaaagaaaag cttgagatca tgagaataat attgccaata
    20221 ttcatcaaag ccaacactac aatcggccga taaacaaatg gcaggatatg cttttttaag
    20281 atatgccgca cagataagcc cattgtctgc gcactaatga catatggctc tgccttagcg
    20341 cttttgacca tcgtgaccat cagcctagca taatacagcc actctaccag aacaatagct
    20401 aggatcatgt tgcctatgcc ctgcccaagt atccccattg tagctagcga tagtaaaaag
    20461 ctaggaaagg cagaaacaac atcagctagc cacagaaaag ctgcctcgag ccttccttga
    20521 taccagccta caaccaaacc aaccacagca ccaatagata gctctaacaa actaatagta
    20581 accgccaaaa gcaaggaata cttagcccca tataacaagc gcgacagcac atctcttccc
    20641 aattggtcag ttcctaataa gtgctgctga ctaggtggca tgagcttact agcaacatca
    20701 acagcatgag gatcaaaggg agcaagataa ggagcaaaca agacacagat aaacaacagc
    20761 aatagcataa cagctgaacc aattacgtat ttgggcatgc ttcctccttt gtcttgcgca
    20821 gacgagggtc aataaaagac actagctctt gagttatcac atggtgtagt aaaaacaaag
    20881 caccaaataa gagcatacag gcctgaataa ccggaatatc tgctgctttc agactcataa
    20941 caaatagact gccaatacca ttccatgaga aaatatcctc aacaataata gagcccgtca
    21001 tcaaataaac aaaggtcaag ctcaagcctg ttgcaatagc aggaaaggca tttctaatca
    21061 ggtgatgctt aacaatataa taggtcttaa cccctcttag cctggcattt tcaacatgca
    21121 gactcgttag ctgctcactg attgcctttc gtatcaaggc agtatattgc ccaatcaagg
    21181 aaaagctaag cgtaatactc ggcaaaatga ggctgctggc acccgccttg cctgacacag
    21241 gcaggagatt tagcttaaca gaaaaggcta taatcaagag atagcccaac caaaagctag
    21301 gcattgacac agcgacaaag ctgaataaac gcaccagccg atcaaacaag gaatgctcaa
    21361 acaaaccact gcctaccccc aaaggaaagg caatcacaag taccagtaaa aaagaggtca
    21421 agcttagcat tagcgttgct aaaaagcgct ccaccaccaa aggcaggaca gggaccttta
    21481 acacgtaaga ggtcccaaaa tttcctacaa gaatgtcaga taaccaggtc acatactgct
    21541 cccataaagg cttgtctaag cccaaataga gcctagcatt gtgaagagct tctggtgtaa
    21601 tactgatctt agataggcgc aaatactgct ctgccgggtt agcggaggat agcttaacca
    21661 gaacaaaggt cactatcgaa atcattagca aggcgccaaa ggtagaaata agcttcttca
    21721 tcatattttc tctcaaccct tcactaagac atcagacaag aattgtcagg atagtcactc
    21781 acaaccagtt cctctgctct atcaattctt gactgcctta tcagcagcac ttttttcaat
    21841 gtaacgcaat ggaagggcat tttcctctgg tgcaaagcgc attgtcttaa aatctccctt
    21901 gcgatatact gaaacaactg actgataggt gagtggaata taaacagcct catcatgcaa
    21961 caatgacaat acctgcttat agcccttgtc taccttatcc ccatctggct caatcaaaac
    22021 agatttaatc aggcgatcaa tctcagcctt tgatggcaaa ctctccaagg caatattttc
    22081 tgggtgacca tgatccgctt ttgccgttaa ggctgtcatc caagcatgag gatcccaagg
    22141 agctccccat gaataggtca gcatcatatc aaactgccct gtcttggcat tagcccagta
    22201 gtcatcctcc tccatagctg tcaagaccac atcaatccca agctttttcc actcgccttg
    22261 gaaatattca accaaatcct tgtctgtcgc tttagttgaa atataaggca cctgtaaacg
    22321 caactgctga ccatcttttt ccctaatccc ttcttggttt tccttccagc cagcggctgt
    22381 cagcatgtcc ttagcctttt ggagattgta ttcataagga actaagcccg catcagcatg
    22441 cggtgttgtt tttgaaaaaa tggtatctgc tgctgtctct gttcctctaa aggtgtgctt
    22501 agcaatagcc tttttgtcaa ccgcatggtt cattgcctga cgaacccgct tgtcctgaaa
    22561 cactgactgc ttagcattta acagcaataa acgagtcgac atgggctgag aaacatcagt
    22621 aacatacttc ttgtccttag catactgcac aaaggtatca agactaatca gaccatttcc
    22681 atagatcaaa tcaatatccc cagcctcaaa tgctaaggct cttgtctcag catcaggcat
    22741 aatcttgatg gttacttcct ttagctttgg tttttctccc caatagctct catgacgtgt
    22801 aaaggtaatg tactcatttg cctttttctc tttaacaacc cattgacctg taccaatcgg
    22861 ctttttaaca ttgtgcttat tggtgtcatc gccatcagga aaaccagcat cagccaaaaa
    22921 cctaatcggt ctgatcattg acaaatcata caaggtagcg ctataagcct cctttagctt
    22981 aatctcaaag gtatgatcat ctaaagcctt gtagctatcc aattgattgg taaagtgaaa
    23041 ccaattatga ttgcccttat tctgctcaga gaaaatcgaa tcaaaattcc gtttaacatt
    23101 ttgagcatta aaatcagaac catctgaaaa tttagcctgt ctcaggttaa aggtataggt
    23161 tttgccatct gggctaatcg tccagctctc tgctaacgcc ggctcaatat tacccttgtc
    23221 accatatcga accaagccct cataaaccat gtcttgaata acaaactgat caggattgta
    23281 gcgatgagga ttgacatcac caaaatcctc accccaagca atcctcaact gatccgtacg
    23341 gtaagaggcc tgcttagcat tttgacaggc cgtcagcagc aaagcaaaaa agaataacaa
    23401 tagcacattc aatttagttt tcattatgtc attaactttc taaagatatt aatctatcta
    23461 attttagatg tggtttatca caaaattaag tatggttaat ttaatcattt tatagccctc
    23521 ttgtcaagaa aaaatgagac aaaatcagcc tagaaaaagc cagaaggcta caaataagca
    23581 aatcgtcaaa atcatgaaca cttcaggctt gctgaggaat attttctaat ggttattaga
    23641 aataatgaac aattacctaa caaaagactc caaaataaag gtaaaagacg aacattcacc
    23701 ttgctgctca gctaccaaga caaacaatcc tgatagcatc aattttcttt aggctcttag
    23761 caattagttg caatatcaga taattttgaa tttaattaaa aaaaacgaaa ctacggagac
    23821 caattatcag aaagctattc acagccagca aagggcatgc taaagtatta tctggaaaaa
    23881 gaaaggctta ggaatgatta tttctaaact aaaaggagag agacaatgaa aaaaacaatg
    23941 aagaagatgc tagcagcctc gacgctctgt atcatcatgt caggcagctt catcagcggc
    24001 tcagctagag tgttagcgga ggaatattat gggtggaatg atgtcactgg gtctaagtca
    24061 ccatttcctc tatacgtgac accaaaaaat ggagataaaa atataaaagt tcaacaaacg
    24121 gttgtttact gttttaacag ggatgggcaa tggccagaaa attgggaaaa acggatatat
    24181 gaatctcctg ataaagttcc acataaatta cccgaatata ataaaaagtc aggaagcgat
    24241 aatctgtttc aattacttaa tcccaaaatt aagataaaaa atccaatggc agctttatta
    24301 gcggttttgg aagatggata tcctacgtca tcttcttcag gagtaaatca aagaacaact
    24361 cagctagcta tttggcattt tacagatgga ttaagcaatc ttgcccaatt tcatcttact
    24421 ccggaagaaa cttcagctta taacaagttg atagaaaaag ggacaaatgc ttctaatcaa
    24481 agtgaaaata aactattaaa taaaacttta gatatttatt cctatataga tgggactggt
    24541 gataagaaac acaattatca acaccttctt ggctccactc caattcctat tgataattct
    24601 aaagaaaata aatgtcaatg tacaaaagtt gacttaatgc gaactggaga tggggttaaa
    24661 atcattgttt atgttgataa caacggaaat aatagatatg acaacggcga caaaatgcta
    24721 aaagaagaaa ctatcaaaca tggtcaacgc ggacctgctg gtgaatctgg gaaaccaggg
    24781 cctaaagggg atcgaggaga aactggagca cgcgggccag ctgggcctca gggcaaacct
    24841 gggaaacaag gacctagagg tgataaagga gaaaccggag aacggggacc tcaaggggaa
    24901 aaaggtgaac ctggaactcc tggtcctaaa ggagaagacg gtaaagacgg ggctcctggg
    24961 cgtgacggac aaccggggcc taagggtgaa aaaggtgacc ctggaaaaga cggacaagat
    25021 ggaaaaccag gggaaaaagg agaacctgga attcctggtc ctaaaggaga agacggtaaa
    25081 gatggggctc ctgggcgtga cggacaaccg gggcctaagg gtgaaaaagg tgaccctgga
    25141 aaagacggac aagatggaaa accaggggaa aaaggtgacc ctggacgcga tggtaaagat
    25201 ggagaaaaag gcgaacgcgg tgaacaaggg cctaaaggag aacgcggtga gcagggacct
    25261 caaggagagc gtggggagca aggacctcgt ggggaaaatc atactcctac cccagaccca
    25321 atgcctgagc cggcacctaa accagaatcc aaacctgaac ctaagccgac acctcaacca
    25381 gaggttaagc ctctgccaga gactaaacct caaaaaccaa ccaagccgtc agcaatggct
    25441 agccaaccaa gtagcaaagc actaccaaaa acaaatgaca ctagcggctt aatgactgta
    25501 cttggaacag gcttgctctc tcttcttgga ttaggcttcc tggcaaaacg caaaagaaag
    25561 caataactaa cacataatca ttagtaatcc attcattatc catttacaag ttatcataaa
    25621 aaagccttat cattccttga ctggtatgat aaggcttttt gtttacccta tatagctcta
    25681 cccttactcc aaaaatcact taaccctagg aaaaggctga ctatcatttt tggccaaaaa
    25741 aagacagaca ccaattcatg atgtctgtct caaaaccaat cccttttagg gtcagtcctt
    25801 aattacttat taaaatgaac ttggatctac cttgataccc acaccttgtg tagttgtgat
    25861 agatacgtta gtcatgtaag taccctttgc agtagctggc ttagccttaa ccattacctc
    25921 atggaaagcc ttaaagtttt caaccaactt gtcagcgtca aatgatactt taccaatgat
    25981 agcttgtacg ttacctgctt tatcagcacg ataggtaatt ttaccaccct tagactcttc
    26041 aaccgcctta gcaacgtcca ttgttactgt accagtttta gggtttggca tcaagttacg
    26101 aggtccaagg acacgtccaa gacgtccaac aatagccatc atatctggtg ttgcaataac
    26161 aacatcaaaa tcaagccagc cgccattgat cttagcaaca aggtcatctt caccaacgaa
    26221 gtctgcacca gctgcctttg cttcttcagc ttttgctcca cgagcaaaaa caaggacacg
    26281 ctgagtttta ccagttccgt ttggcaacac catcgcacca cgaatttgtt ggtctgcctt
    26341 gcgaacgtcg atgtttaagt tataagcaac ttctacagaa gcgtcaaatt ttgcgaagtt
    26401 agtttctttt gcgagtgcta cagcttcctc tacactgtat gcctttgtgc tgtccacttt
    26461 ttcaagtgct gcacgcattt gtttgctttt tttagccatt tttatcttct ccttgtaatg
    26521 tggtcatatc gatttgattt aaaaatctcc cacgtcactc atctctatga tgaagtcttg
    26581 cgggtaataa gggcaggttg ctgattaatc agtaacggtg aatcccatag aacgagcagt
    26641 accttcaatc atacgcattg cagcttcaat gtttgcagcg tttaaatctg gcatcttagt
    26701 ttcagcaatt tcttgtactt gtgcacgagt aactgtcgca actttagttt tgttaggtgt
    26761 acctgatcct ttttcaacac ctgcagcctt ctttaaaaga acagcagctg gtggtgtctt
    26821 tgtgatgaaa tcaaatgatt tgtcttcgta aactgagata acaaccggga taatcatacc
    26881 agcctgatca gctgtacgag cattaaattc cttagtgaat cccatgatgt tgatacctgc
    26941 ttgaccaaga gctggtccaa ctggtggagc tggtgtcgct ttaccagcag ggatttgaag
    27001 ttttacaagt ttttcgactt ttttagccat ttttaaaaat cctcctgttg tggttttggc
    27061 ggtaattcac gatttttacc tcccacaggt atgctagagc ataccttacc attatacctt
    27121 attagacaga taaatcaagt cattttcaca aaaatgttac cgcaaatagc agatgtctcc
    27181 tatggcacta gcagtacaag catgtgaggc ttccaaggag ccgcttctag ttgactttta
    27241 agcgtttttt tattataaca aagctatgca taagaaagtt acgatcaaag atgtcgcacg
    27301 cgaggcggga gtttctgtgg ctactgtctc ctatgtcatc aataacagag aagatcaaaa
    27361 aattagccct gaaacgcgca ataaagtgct gcaaatgatt aatcttttaa attatcggcc
    27421 aaaccaagcc gcaaaatcac tcgtgacaca aaaaagacag ctaatcgccc tttactacaa
    27481 agagcacagc tctgttttaa aaagagcaga gcagcttcac tttatcaccc agctatctgc
    27541 ctttctttac acaaagcact atcacttgat ttgccttaat caagaataca tcggaaaata
    27601 tgatgtagca gatgtcattc tcaccctaga ggtcaccaaa gaggaatttt acaagatcgg
    27661 aaatagcaac tttgttcctt tgattgctat tgatagtatt attgatgatc ccttattttt
    27721 ccagattaat agtgaccctc atctcctgtt caataaagcc agtgcttatt ttgcagggga
    27781 gccctttgaa ctggttagcc tgcctattca aaaccaagaa atcactcaag gactcgctca
    27841 acagtttgat aacatttgct ggattcactc tatttgcgac atcgaaagcg tgtctaaggg
    27901 gaatattcta gttattgatg atactgtcaa tcatattctt agtaagcaca agaacaaact
    27961 atacctgcca agtatctcag aagctaagct tctgaagctt tttcaggcta ttgagtgggc
    28021 ttccaaaaga gaagcaatca acaatcataa tattttggtt taaccatgat aagagcttag
    28081 caacaagctt gctgctaagc tctttttgtt ggtcaagagg ccaactttat ttaggtatca
    28141 gtcagtgtgc cagctctttt agccactaaa agcaggaatt agtttacaag tctaccaatt
    28201 gggtataaaa tagacttatg atcatctaca aattaacagc cttagccttt attatcctga
    28261 ctcccttatt ctctatgata atgatatccc tattgagact gggacgaaga ggccttaaat
    28321 ttcctgattt agccttacca ctttttgttt ttgaaattgt tattgtatca ggaaaatttt
    28381 tcacccatca tttactacct tattacctga ttgttatgtc cttgttggcc attgttatgg
    28441 cactcttact gattatcaga atccagcagt tttcttaccg ccgatttttc aaactatttt
    28501 ggcgagtagg ctttttagtc acactactct tttacctgat gctagttggt cttattttta
    28561 tcgtttagtg ccttaccaga catggcttca agcctagcag tctgaatctg ccaattaact
    28621 ctagcactat cactcaaaag gaagctgtct ttgaactttc tgcttgagtg ggactttttt
    28681 caaagcaatc aatccatatc aaaccagcat tagagcatgc ggcttgatac ggattgattg
    28741 ctttaagaac tgttgtaaaa tatcaaaaat tcagttttta ataaagtcca ttagctattt
    28801 ctacactaaa tatcatttaa gaaaacagag gctaataact agagttcact ataacctaaa
    28861 atcaccaata cctccgatta acttaattta accaaactac tgtatatacc aaagtttttt
    28921 acgtgtcatt ataatacgtt cagataaatc atctaatgca cgatctttgt tgagaccaac
    28981 atcatattga atacccatta atctatctag aaactcaaga cgatatttct tcataatatt
    29041 tcgtgagtgt ccttctggaa aatgctcatc aataagcgaa cttacaatct caactttatt
    29101 actaatttta aaatagcgac ttttcaaaga ttgtaattct tctttaattg ctcttaattt
    29161 agaaaaacta tctgctccat aaaccttagc ttccatttca ttagcctcag aataacttag
    29221 ttttattgtt gcaataaaat ttctaagtac ttccttctct tttttaagct ccctttctgt
    29281 cggactcatt ctatagtaat attgacgcca acgatattga gaagcgttga ctttttgatc
    29341 acttatagtc aaaatagtca atgctactac actaaagaaa aatattcttt t
//
LOCUS       DARYLD010000026        29140 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYLD010000026 DARYLD010000000
VERSION     DARYLD010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29140
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..397
                     /locus_tag="TU651_000992"
     CDS             <1..397
                     /locus_tag="TU651_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897002.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TU651_000993"
     CDS             441..1106
                     /locus_tag="TU651_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897003.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDRIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TU651_000994"
     CDS             1103..2080
                     /locus_tag="TU651_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL0897004.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TU651_000995"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TU651_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL0897005.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TU651_000996"
     CDS             complement(3407..3844)
                     /locus_tag="TU651_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL0897006.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
     gene            4045..4737
                     /locus_tag="TU651_000997"
     CDS             4045..4737
                     /locus_tag="TU651_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0897007.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(5113..5589)
                     /locus_tag="TU651_000998"
                     /pseudo
     CDS             complement(5113..5589)
                     /locus_tag="TU651_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TU651_000999"
     CDS             complement(5802..7364)
                     /gene="guaA"
                     /locus_tag="TU651_000999"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL0897008.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            7651..8349
                     /locus_tag="TU651_001000"
     CDS             7651..8349
                     /locus_tag="TU651_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0897009.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            8561..8893
                     /locus_tag="TU651_001001"
     CDS             8561..8893
                     /locus_tag="TU651_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL0897010.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            8908..10479
                     /gene="ffh"
                     /locus_tag="TU651_001002"
     CDS             8908..10479
                     /gene="ffh"
                     /locus_tag="TU651_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL0897011.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(10632..11855)
                     /locus_tag="TU651_001003"
     CDS             complement(10632..11855)
                     /locus_tag="TU651_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0897012.1"
                     /translation="MINVAFNSKIGISAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQN
                     ERIGIFQGDNQVASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKK
                     KRALLIKFDPMILLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRF
                     QANCYTNADIEASFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVAL
                     RNEAYFRQLMTTYGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARL
                     TDQKQSLQRYLSEFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYL
                     LYPKVFMDAYHDDIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHL
                     ANLLYKIRKQLKHRH"
     gene            complement(12080..13051)
                     /locus_tag="TU651_001004"
     CDS             complement(12080..13051)
                     /locus_tag="TU651_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL0897013.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(13364..13804)
                     /locus_tag="TU651_001005"
     CDS             complement(13364..13804)
                     /locus_tag="TU651_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0897014.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(13801..14736)
                     /locus_tag="TU651_001006"
     CDS             complement(13801..14736)
                     /locus_tag="TU651_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0897015.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(15174..15587)
                     /locus_tag="TU651_001007"
     CDS             complement(15174..15587)
                     /locus_tag="TU651_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL0897016.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(15685..16440)
                     /locus_tag="TU651_001008"
     CDS             complement(15685..16440)
                     /locus_tag="TU651_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL0897017.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TU651_001009"
     CDS             complement(16445..18940)
                     /gene="gyrA"
                     /locus_tag="TU651_001009"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL0897018.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            19132..20115
                     /locus_tag="TU651_001010"
     CDS             19132..20115
                     /locus_tag="TU651_001010"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL0897019.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(20320..21687)
                     /locus_tag="TU651_001011"
     CDS             complement(20320..21687)
                     /locus_tag="TU651_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL0897020.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYGVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(21937..22539)
                     /locus_tag="TU651_001012"
     CDS             complement(21937..22539)
                     /locus_tag="TU651_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL0897021.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(22540..23517)
                     /locus_tag="TU651_001013"
     CDS             complement(22540..23517)
                     /locus_tag="TU651_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL0897022.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(23520..24779)
                     /locus_tag="TU651_001014"
     CDS             complement(23520..24779)
                     /locus_tag="TU651_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL0897023.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(24791..25222)
                     /locus_tag="TU651_001015"
     CDS             complement(24791..25222)
                     /locus_tag="TU651_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0897024.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(25236..25829)
                     /locus_tag="TU651_001016"
     CDS             complement(25236..25829)
                     /locus_tag="TU651_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL0897025.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TU651_001017"
     CDS             complement(25801..26649)
                     /gene="prmC"
                     /locus_tag="TU651_001017"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL0897026.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TU651_001018"
     CDS             complement(26646..27728)
                     /gene="prfA"
                     /locus_tag="TU651_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL0897027.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(27770..28339)
                     /locus_tag="TU651_001019"
     CDS             complement(27770..28339)
                     /locus_tag="TU651_001019"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL0897028.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            28526..28711
                     /locus_tag="TU651_001020"
     CDS             28526..28711
                     /locus_tag="TU651_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL0897029.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            28766..>29140
                     /locus_tag="TU651_001021"
     CDS             28766..>29140
                     /locus_tag="TU651_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL0897030.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         8615 a         6031 c         5494 g         9000 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgaccgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tataacatgt ttggcattaa acctaagaca gcttactgtc ttttcgatat aaacataaaa
     3961 agcttgaata ttcttataag ctatgttata ctctggtaaa gttaatactt tactagagta
     4021 tactgacaaa ggagatttat gctgatgttt tctggtattc aattaaaaac agcacgttta
     4081 tcaaggcata ttagccaaga acagctagga cagcttttag gagttaataa aatgactatt
     4141 tccaattggg aaaaggagaa aaatagacca aatcaaaagc attttgaaga gcttgtgagc
     4201 atttttcaat tacctgctga gtacttttat caagaaaatc gtcttttact tccctatagt
     4261 cagttaagcg cctctaataa agaaaaagtt atcagctatt ctgagagctt acttgaacaa
     4321 aaagaaaaaa taattgcttt accagctaag aaaaagacac tttaccctta tcgtgtttat
     4381 gaaaggttgt ctgcagggac tggctattct tactttggtg atggtaattt tgatgttgtc
     4441 ttttacgatg agcagttaga ttatgatttt gcttcatggg tttttggtga ctccatggag
     4501 ccaacctatt tgaatggcga ggttgttctc atcaaacagg atagctttga ttatgacggt
     4561 gctatctatg ctgttgagtg ggaagaacaa acctatatca aaaaagtata tcgtgaagaa
     4621 aatggtctgc gtttggtttc attgaacaaa aaataccctg ataaattcgc ttcctttgat
     4681 gacaatccgc gtattattgg aaaaatcatt gccaacttta tgcccttaga tgtataagcc
     4741 tttgtattag cttaaaagca tgactgttgt acaaccaaac tcattgcatg acattggtgc
     4801 attatttttg aagtggcttc tacttctttg atttactttt ctgcattaaa aagcccatta
     4861 aaggtttttg aaacttatta cttagacaaa ggctctatta aaaatcataa ccaaccggtg
     4921 gtggtttatt tgtcatgtac cttgcatttt gtgacagact tcataaaacg aacaaaacac
     4981 atcgctaaaa gattttacca tcttaaagtt atgtgttttt tgtataaaaa cttatctata
     5041 tgcttgatta accaactgag ataaatagat tattatttca tagagaagtt tgttatctaa
     5101 tccaaataat cgtattatcc tcttaagttc ctcaacatta taaccatcac aatctgttgg
     5161 cagtttattt ttttcaagcc acttatcaac cactgctatt cccaaagaaa ttgaaaaatc
     5221 tttttcttta tcaaacttac acaattccac tgccaaagtc aatacaaaat tcctgtgaat
     5281 attatcgtaa ttttcatcaa ataattgcct ttccaaaccc acaatagata gccgaataaa
     5341 tatgtatctc cctatttctt cgtcaatacc ttcagtagcc ttaatagctt cttggacaac
     5401 attattccag aaagcatttt tattacgctc ttctataaaa gttttaagtt tcattttgaa
     5461 aatatcagta atttgaccaa ctgctttatc aataacctat gaaacaatat tcttcatcat
     5521 tatgattttc tcctcgtata cataaataat tgtatctttg ctatataatt gtggtatctc
     5581 ttcaatcaac caatattgtt cttaaactat tccctcaaaa gccttccacc aaaacgatgg
     5641 aaggctttta aaccattcac ctaaattcaa caactccctt ttgaacttgc tattttagct
     5701 ttttagtatc aaagcagtat cactcaagag ttttttgttt ccacaaaccg caaaaaccca
     5761 ctgttttcaa cactttcatg gcagtaatat atttgcttct gtcactccca ctcaacggtt
     5821 gctggtggtt tgctggtgat gtcgtagaca atgcgattaa cgtggtcgac ttcattgaca
     5881 attcgaactg agattttctt tagaacttcc caaggcaatt gggcaaagtc tgctgtcata
     5941 ccatcaattg aggtgatagc acgaatagcg atggtatagt cataggtgcg accatctccc
     6001 ataactccga cggaacgaac acctgtgtta actgtaaaat attgccacac atcacgctca
     6061 agtcctgctt tagcaatttc ttctcgaagg atagcatctg actcgcgaac tgtttcaagc
     6121 ttttctgctg tgatctctcc catgacgcga atggcaaggc ctgggcctgg gaaaggctga
     6181 cgccagacga cttcatctgg cataccaagg gccgtaccaa gagcacgaac ctcatcctta
     6241 aagagtgtat tgaggggttc gattaattca aactgcatat cctctggcag accaccaaca
     6301 ttgtggtgag attttatcgt ttgagcagtt tctgttccag attcaatgat gtctgtgtaa
     6361 agcgttcctt gtgcaaggaa gtcaacgccc ttaagcttgc tagcctcgtc atcaaagacg
     6421 taaacaaact cattaccgat aattttacgt tttttctcag gatcctcaac gcctgcaaga
     6481 agatctaaaa agcgctttga ggcatcaaca cgaataatat tgagaccaaa tcttccacca
     6541 agcatttcca taacttggtc accttcattt ttacgaagaa gtccatggtc aacaaagata
     6601 caggttaatt gatctccgat agctttttgt aaaaggacac caacaactga agaatcaaca
     6661 ccaccagaca aacctagcaa aaccttacga tctccgactg tttcgcgaat tttagcaatt
     6721 tgcatgtcaa taaaattatc cattgaccaa tcaccacgtc caccacagat agagatagca
     6781 aagttcttca aaatatcatt accatagaca gagtgtctta cctctgggtg gaattggata
     6841 ccgtagagcc tcttttttgt attttccata gcagcgtaag ggcaatcgtt agaatctcct
     6901 acaagatgaa agccctctgg gatttctgta acagcatcac catgactcat caaaacaagc
     6961 tgctcatctg gagtgcccgc aaataatgct gatgcagaac gtaaacgtaa tgatgattga
     7021 ccatattctc ggtgacctgc ttgaccagct gggactacct tacctcctaa ggtatgtgtg
     7081 attagctgca tgccatagca aatccctaaa attggaatcc ctaattcaaa gatttcagga
     7141 tcaataccaa aggcatcagt tgcataaaca gaatttggcc caccagacag gacaatcccg
     7201 attggattga tgtcacgaag ctcttgcgca gtgatgtgat ggcttttgag ctcagaaaaa
     7261 acaccaaact cccgaatacg tcttgcaatc agttgattgt actgactacc ataatcaaga
     7321 acgataattt tttgaatatc attcaacatt gaaatttcag tcattataac cctttcatta
     7381 tataccagaa ccttgttagc tgatagtttt caattaattg tagcatattt tcactaaaaa
     7441 ggcattagct tttcaggtga tgtgatgaaa aaataagctt tttgcagaga tattaaaatg
     7501 aatgacctca actatcttat gtatgactac tattgtcagt cttagcatga aaaagctgat
     7561 tgatgatgag tgtttttggt aataattggg ctgctattta ggctgaaaat atgataaaat
     7621 aaaaccatca tcaccctcaa ggagtaaagc atgctgccag cttatataaa aattcatgac
     7681 gctattaaaa aagacatcga aaaagaagtt tggactattg gtagtcgcct gccaagcgaa
     7741 cgagatttag cagaacattt tgaggtcagt cgcatgacgt tgcgtcaggc aataacactg
     7801 cttgtagagg agggaattct agaaaggcgt gttggtagtg gtacttatgt tgccagccat
     7861 cgcgtacaag agagaatgcg tgggaccact agctttacag agatcgtgaa ttctcaggga
     7921 cgtaagccat cttcaaaact gatttcctat caacgtcagc tagcaagtga tacagaaata
     7981 aatcaattgc acttagaaga atcagattac gttattcgaa tggagcgcat tcgttatgca
     8041 gataaggttc ccttagttta cgaggtagca tctattcctg agaaatttat taaaaatgtc
     8101 aaaaaaactg atattacaga gcactttttc caaaccctaa cctcaaacgg ttatgaaatc
     8161 ggcaaaagtc aacaaaccat ttacgcgaaa atagccagtg agcgtgtcgc ctcttatcta
     8221 gaggtcgcta aggggcatgc tattttagca ttgactcagg tttccttttt tacagacggt
     8281 aggccctttg aatatgtgcg tagccaatat gtaggtgatc gctttgaatt ttatttagaa
     8341 aataattaat cataagcaat gatgtttaaa taacattgat aggaagtggc tcaccacttc
     8401 tttttttcaa cacttgtcaa gtatatcaat atttcaagaa cagttattaa aacaagctac
     8461 tattatcctc atttttgctc taagaaagct tcctgataaa aggctgatcg ctatcattta
     8521 ccactgttaa aaatgctcat gatgtgataa aatgaagatt atggaaattg aaaaaacaaa
     8581 ccgaatgaat gctctttttg aattttatgc tgccttattg actgataaac agatgaacta
     8641 tatcgagctc tattacgctg atgattatag tctggctgaa attgctgaag aattcggtgt
     8701 cagccgccaa gcagtttatg ataatattaa gcgcactgaa aaaattctgg aagcctatga
     8761 aatgaagctt catatgtatt cagattatat tgtacgtagt gaaatatttg atgatattct
     8821 tgcaaaatat cccagtgacc actatttacg tgacaaaatt tccattttaa ctagtattga
     8881 caacagagat taagaggagt tatagctatg gcatttgaaa gcctaaccca acgtttacag
     8941 gacgttttta agcacattcg tggtaaaaaa accttatctg aagccgatgt tcaggaagtg
     9001 accaaggaga ttcgtctagc cttattagag gcagatgttg cacttccagt tgttaagacc
     9061 tttatcaagc gtatacgtga gcgagctgtt ggccacgaaa ttattgatac ccttgatcca
     9121 acgcaacaaa tacttaaaat tgttaatgag gaattaactg gtatcttagg atcagaaacc
     9181 gcggagcttg ataaatcacc taaaatccct actgtcatca tgatggtggg cttgcaggga
     9241 gctggtaaaa cgacctttgc aggaaaatta gccaataagc tcatcaagga agaaaatgct
     9301 cgtccattga tgattgcagc agacatctat cgtccggctg ctattgacca gttgaaaacc
     9361 ttgggacagc aaataaatgt tcctgttttt gatatgggga caaatcattc agcagttgat
     9421 attgttgcca atggtttggc acaggcaaaa gagaaccgtc atgactatgt tttgattgat
     9481 acggcaggac ggttacaaat tgatgagaaa ctaatgggcg agcttcgtga ggttaaagca
     9541 ctagctaaac caaacgaaat ccttcttgtt gttgacagca tgatcggaca agaagctgcc
     9601 aacgttgcct atgaatttaa caatcagctc gatatcactg gagtagtgtt aacaaagatt
     9661 gacggtgata ctcgtggtgg tgcggccctt tctatacgtg aaataactgg taagccaatc
     9721 aaatttaccg gaactggtga aaaaatcacc gatattgaaa ccttccatcc agaccgtatg
     9781 tcaagtcgta tcttgggaat gggagacctt cttaccttga tcgaaaaagc aagtcaggaa
     9841 tatgatgaga aaaaatcatt agagcttgcc gcaaaaatgc gtgagaatac ctttgatttt
     9901 aatgacttta tcgagcaatt agaccaagtg caaaacatgg ggccaatgga agatctgtta
     9961 aaaatgattc caggtatggc aactaatcct gctctagcca atattaaggt tgacgacaag
    10021 caaattgctc gcaagcgtgc tatcgtttct tctatgacac ctgaggagcg tgagcagcca
    10081 gagcttttaa caccaagtcg ccgccgtcgc attgcagctg gatcaggtaa tagtttcgtt
    10141 gaagtcaaca aatttattaa agattttaac caagccaaag ccatgatgca gggtgtcatg
    10201 tcaggtgata tgactaaaat gatgaaacaa atgggaatca accctaataa cctccctaaa
    10261 aacatgccaa atatgccagg aggcatgcct gatatgtctg cccttgaagg aatgatgggg
    10321 caaggtggtt tacctgacat gtctgcattg ggtggtgata tggatatgag ccagctcttt
    10381 ggaggtggtc taaagggtaa gattggtcaa tttgccatga agcaggccat gaagcgtcaa
    10441 gctaataaga ttaaaaaggc caagaaaaaa cgaaaataga ctaaaagaat ggttgccttg
    10501 tattctgcct ctaatcgtta gatgctattc taatttggag tgcaggtcag tagcgaccat
    10561 cttttttata aatacaatca ctagatcttt ggttctaacc attaaacatg atatcatttc
    10621 actattagct gttagtgcct gtgctttaat tgctttctga tcttatatag caaattagcc
    10681 aagtgataaa aaggactgat tgctaggttg aattctccaa taaactcttc gatagttgga
    10741 ctgaaattgg acttaaatgc tgtcaatccg tccttgaagg agccatcaat gccgcccata
    10801 ttcgcccaag ctatatcatc atgataggca tccataaaga ctttaggata aagcaggtac
    10861 tgaggataaa actttttaaa gtcatcattc atgccagcat agagcatttc catcgtgttg
    10921 ccatatgaaa tcgataaaat gcccgcaatg acaacctcat ctggatattt atccaagaag
    10981 tccttgaatt ctgatagata acgctgaagc gattgctttt gatctgttag tctagccagt
    11041 cgcttttttt gatgcgcttg cgtttgagca agctcttgtt caacagcttt cagctgaagc
    11101 tcgtaattct tgagtttttc tggaagatta acctttgcta aatgcaaata agcattgtcg
    11161 ccataagtcg tcatcagctg tctaaaataa gcttcgtttc ttagagcaac tccttttctc
    11221 ttttcagtta aagagataag gtcagcaaat gtatggagat cagactgatt acctcgataa
    11281 gctatcacgc cacgttgcct agcatccttc atcaatcgct tggtatgctt aggaaaggac
    11341 gcttcaatat cagcattagt gtaacaattt gcttgaaaac gcggctgaat agtatcagat
    11401 agcttggttg ttgggcctgt ccaatgggca ccaaatcgct ttaaatgctt aataatggtc
    11461 agagccttgg aattatcagg tgctttctca ccaagctgat gctgctttag cagaatcata
    11521 ggatcaaatt taatcaaaag agctcttttt ttcttaccat atgccttcaa ggttttaatc
    11581 gtaaatgcca ctagatcagc attggtatag tccatcactg gacctcttgg aatataaatc
    11641 atcgtcatac caaacggcaa aggcttaatc agcaaggaca tagaagccac ctgattatct
    11701 ccctgaaaaa taccgatgcg ttcattttgc cactgatttt taacagctgc ccatgagctg
    11761 ctctgcaaga ggttaacctg ctggtgctgt ttgacaaatt ggtcatgctc ttgagctgaa
    11821 ataccgattt ttgaattaaa agctacattt atcatcatat ttcctcatct ttaagtatct
    11881 aaatatctga tcttgaaata gatctgcttc tacttaattt attcgaaaaa tagtttgaaa
    11941 aataattgct ttttttgatt ttcaatttga ttatttttag ctgctcaaat gaataatcga
    12001 tttcggttta aataagttta aaaaatagga ctaattccta atgaaatcag gaattagtcc
    12061 tactactttt atctatttat cagttaccca ttaggctgtc aatcaatcct ctaaagaaat
    12121 caataatttg ctgaaggatt ccctgtccag tctttaaggc ttcagtagca tcaaagttca
    12181 cgttgatatt tttaaaggta gatccggcct tttcaacaat actatccttt aaagcattca
    12241 gcgttttggt gaagttttca ttggaaatca cgccactatt tgagaggtta agcgcgaaat
    12301 tgataataag gttaatctga tcaggtgtta ctgccttggt taacccataa tgatctaagg
    12361 tttctgttac aatttggcgc accttttcct cattaacccc ttctccagcc tttgcgacag
    12421 cagctttaat atcagtaagc gcaacattta gcttatctgc atcatagcct gttttacctg
    12481 cattttcggt attgatatta gatagggttg atagctcctc ttgtgccagc ttcttgtttt
    12541 cctctgggac tttggcacca tttttttcga gtgaataata aataccggct aaagctgatt
    12601 ctccagtaac tgggattggt gcagctacag taatattggc atgctcaatg cccaaggtca
    12661 cagcggcgtt acgatacata tcttgcgtca ccttagtgat attttcaggt gttacaatag
    12721 ttaccttaag cgtttcttta gctcccagct tttgaatcct aactgaggaa taaagctgta
    12781 ggctcggatc atctgctaca ttcatgatac tagcataggc agttgtattt agggtgctta
    12841 atttgttatc agaagcacta ttgtagtgaa gcaaggccaa ggtttgctct ctttgctcag
    12901 cagacagtga atagcctaaa acgtaatcag gctgaacata ggtttcatca attacctgtt
    12961 gaacattatt agctgcagcg tgtactgttt gaagcataaa taccgaagcc aaagccatac
    13021 tggctgctat taatttcttt tgataagtca tttttctacc tcttttgtgt tataaatttt
    13081 cctttacgag aatcctccag aaaagacgat taaagccaaa gtatctaggt gcctagtaag
    13141 accgttttac ttagctctgc aaagggcaat attcctagtc tttttcaaaa tctaacgcct
    13201 ctattgtagc atttttacct caataagacg attaaaaagc tgaaacaaag catagctaga
    13261 atggccaagc actattttta caacaaaaaa actagtgcat aatggcagct tagatgtagc
    13321 tactatcact agtccaatga ttatcttatg cagcaaccag tctttatgat ctgaggtttt
    13381 cttgatggtt attgtccttt aaatagaaat aataatgatc atcagttttg atgacatagc
    13441 catttttaac ctcattaatc acgtcctttt gatcaaactg gtagtcctta ggcggtaata
    13501 actctgagga aaaaaggcta tcataaggca cctcaccatt gtaaaaatgg taatggtcac
    13561 catgagaggt aacaaaacca tcatccgaga tagacacaat aatttgctct gctgctatcc
    13621 cctcttcctt gctaacttca ttaggacttt tgtcagtctc tttctttaag gctttgcacc
    13681 ttttttccaa ttgatgagat gattttagct tcttgcctgt gctatcttgg gctttaaagt
    13741 cacaagcgga caaaggaaat aatagtaaga tagtgaataa cgataaataa gcttttttgg
    13801 tcatgtttca ctctccaata cacgatatag tgtttctaaa ttcattttta aatgctctag
    13861 ataagttttt tgatcagctg gaaccacctc aagcgggctt aggatatcaa ttgctacacc
    13921 gttactttga gccaaggttt tggctagctt atctgaagca ttttcttcga cgaaaatcgt
    13981 cttcacatca tattttttga taaagcggtc aatttgagct aattggcgag gactaggctc
    14041 ttgctcagga gatatccctg caattcccaa ttgctttaga tcaaatctct tagctaggta
    14101 ggaaaaggct gtatgctgtg tcacaaaggt tttcctacct agagattcaa acttttcctt
    14161 ataggtcttc actaattttt gagccttagc cttaaaacgc ttagcatttt gcaaataaac
    14221 tgccttgtga gcaggatctt tttgactcaa taaagctgca atctgctctg cctcttgact
    14281 agctaagata ggatcagtcc aagtgtgagg atcatacaag gcatcggtat tcattccttt
    14341 ttttatggtg aagtgctcca agccttgaac cttgtctaat gttagatgtg atgtcccctc
    14401 catgactgct aatccctttt tttccagctg tggtgccaaa tccgcagccc aagcttctaa
    14461 tatcttggaa tggtaaataa agacatctcc atcgtaaacc ttagcaacaa ctgtcggact
    14521 tggctcatac gagtgtatgc tagtgttttg ggcaatgacc tgaacatcat ttaaatcccc
    14581 gcaaatctcc tttgtcatag cataaatagg ataaaagctt gtttttatga ccaaaccggc
    14641 cttcctactg ctagagctct gatgacaggc tgatagaccc aaaagtactg ctaatagtcc
    14701 tactgcgaca attgttttct tgaatcctct aatcatatct actctcttaa ctagttaatg
    14761 acctaaaaag gataccatga tttaactgaa atgtcaatat tttatcattt tagcgcacga
    14821 cgtacacgca tgaagaaaat gcatgtaagc cttttttagc cccatgcatt ttttaatcta
    14881 tttctagcgt tttgacattg caatatcatc agtttgtcaa tttcaatgtg atgacttcat
    14941 cacattttgc taaaaaggcc atagtgatga taaaaaaccg ctaccagaaa gcgtaaatgt
    15001 cttcttgctt ttgtcgtgat tttagtgaac cgcctaccaa ctgaactgat gctggcttaa
    15061 ccatttcctg gccaccatca aaagcctgcc tctcaattaa caagcttact caaggaagag
    15121 gtgactgagc catgcatccg tcttagttat gactaacagc ttatcttggc atttcattca
    15181 tgtaattcca gtggcaggcc atcaggatca aaaaagaagg tcatcttctt accagtataa
    15241 tcatcatacc taagaggctc gacagcaatg cccttagcca ttaattgttc aatataagct
    15301 tcaataggct taacatgaaa agctaaatga cgaagcccac aggcctcttt gtcatattcg
    15361 ggcctaccga tacgcttagg cggtgcctga taagctggat cagtcttttt attgccaaaa
    15421 atctctaatt caatggctcc acattttaaa tccaatttgt aatcatgtct atcaggccgg
    15481 tgattttcac gaataatctc aaagccaagc ttattgacat aaaaatcctt agagacctca
    15541 taatccgaaa caatgatagc aatatgatga atagccttaa gctccatatg atttagttcc
    15601 tttattaaat aaaaaaagtg aaacaaagca atgccaagat tactttgttt cacccctcgt
    15661 agcgacccct cgcctagatt aggcttaggt tgacatctga ttgtaagagt gattaaaggc
    15721 cttcaaaaca tcgtcaggtg ctttgttaaa ctcatactcg tttttgattg ctcctttgac
    15781 aatgattcgc tctgttgcct cataatccgt acaggtgacc aaggttacct cctttagccc
    15841 tggtgtgtca ttgataacat ctattctctc aggtgtgacc gtaaagacgg cattgatctc
    15901 gtactcgtaa atacgctcct tatctgtaag gtaaatagac atcccttctt ttgctctttc
    15961 aagcggtgag aataacattt cagaagagcc tgttagtcca aaaatatgat gactggctaa
    16021 ggagtaattg ttttctcctc ccataacctg gtcctctttc atggtaccag caccgtatat
    16081 aagctctgtg ttgccaagcc ctttaaagat tggtaggtta ataccaagct ctggtatggc
    16141 aatacctcct attactggaa gctgctgggc gtccatttga gcctgtaaga cactttcggt
    16201 gctaactggc tgaactgctt gaaaatcaaa gcttgacttt gcttccttat tctttttaat
    16261 cgtctttttt gaaacctttg taacttgata tttattagaa ttccaagcaa tcagggtgtt
    16321 tctaatgggc ttgttaaata acaaggctaa gcctatgatt aacaataaga cgactagaat
    16381 acctctagca aaggacatct ttcttcgttt ttgtcttctc ctgtgggttc tttttgccat
    16441 tcatttactc cttgctagaa tttattggtg cttctgttaa agctgtatca gtctgagcga
    16501 ttgctgttgg atcgttgtct tcagcctgta ccaaggtaaa ggtaacaatc ttagaatctg
    16561 tatctagcct cataacctta acaccaagtg ttgaacggcc agtctgagaa atacttgaaa
    16621 cattggtacg aataatcaca cccttcgttg tgatcaccat aatatcctca ctgccatcaa
    16681 cagtcatcag gccagccaac tggccatttt ttgcggtgat attagctgtt ttgattcctt
    16741 ttccacctcg acccttagtt gggtattcgg ctgcactggt acgcttacca tagccatttt
    16801 cggtgatgac taagacctct tgcttgtcat tgatacgaga agctccgaca acccaatctt
    16861 cctcacgaag cttgacacca cgaacacccg tagcgctacg ccccatgcct cgaatggtag
    16921 cttcattaaa gcgaacagaa taacctgatc ttgttccaat gataatatct tcctgaccat
    16981 ttgtcaagag aacattaatc agctcatctc cttccttgag attaagggct cgtagaccat
    17041 tctgacgaat attgctaaac tctgatacct cagttcgttt gacaatccct tgctttgttg
    17101 taaagaagaa atatttatca agaatgtctt cttttttagc attgataatt gtttgaatgg
    17161 tttcaccatc atctagcttt agtagattga taacaggaag tccttttgca gcacgtccat
    17221 attctggaat ctcataggcc tttaagcgat agacgcgccc aaaattggta aagaaaagca
    17281 atgtgtcatg tgtacttgtt gagacaagct cacgaacaaa gtcatcgtca ttgacacctg
    17341 ttccctgtac accacgacca ccacgctttt gagatcgaaa ctcgtcttga gcaaggcgct
    17401 taatgtagcc attgtttgat agggtgatca aaacatcttc ttcctcgatc aaatcctcat
    17461 cttctaatga caatacctca ccaatcatca attctgtgcg gcgaggatta gcgtacttgc
    17521 gcttgatctc ctccatttct tccttgatga tggcttcgat acgctctggc cttgccaaaa
    17581 tatctgccaa atctgcaatc aaagccagta ggtcatcgta ttctgattga attttatcac
    17641 gttccaagcc ggtcaaacgg cgaagacgca tgtctaaaat agcctgactt tggcgttcag
    17701 acaagtcaaa acgagacatc aattctgctt gtgcgataat atctgtctcg ctattgcgga
    17761 taatggcaat aacctcatct agatggtcaa gagcgataag taagccctct aaaatgtgtg
    17821 ccctagcttc tgccttgtcc ttgtcaaatt gagtcctgcg tgtaatgacg tccttttgat
    17881 gtagaatata attatcaata atctgtctca gtgacaagat tttaggaatc ccgccttcaa
    17941 tggctagcat attgaagcta aagtttgtct ggagacttgt caatttgaat aggttattta
    18001 aaatcacatt agcagatgca tcgcgacgga cttcaatgac aaatcgtacc ccttgtcggc
    18061 ttgattcgtc acgaacagct gtaatgccct caatacgctt ttcttgggct aagcgaacaa
    18121 tatgctcatg gacctttgtt ttattaatgc cataagggaa ttctgtgacg acaatccgct
    18181 cccgtcctgt actagtggtt tcaatctcgg tgcgtgaacg caaaacgatt gatcccttac
    18241 cagtctcata agccttatga attcctgaac gtcccatcac caaggcacct gtaggaaaat
    18301 ccggccctgg aagaacctcc attaaatctc tggtagtgca gtcaggattt tccatgacca
    18361 tcttaacagc gtctatggcc tcagctaaat tatgaggtgg aatattggta gccataccaa
    18421 ctgcgattcc ggtggcacca ttgaccaata aattggggaa gcgagccggt aagactaagg
    18481 gttctctttc attaccatcg tagttatcct gaaagtcaac agtattttta ttaatatcct
    18541 ttaagagctc tagcgcgatt ttgctcatac gagcctcagt ataacgctga gccgcagcac
    18601 cgtcaccgtc catagaacca aagtttccat gaccatcgac aagcatgtga cgatagctcc
    18661 accactgggc catacggacc atcgcttcat agatggacga atccccatgt gggtggtact
    18721 tacccatgac atcaccggta atacgagcag attttttatg tggcttatca ggtgtgacgc
    18781 ctagctcatt catgccataa aggatacgac gatgaacagg ctttaagcca tctcgtacat
    18841 ctggaagtgc tcttgctaca ataacgctca tagcataatc aatgaaactc gttttcatct
    18901 cacttgtcag attgacgtca actaaatgtt tatcttgcat ttaaggaatg ctccttttct
    18961 agtcaatact cttttaatta taccataaaa tccttatttt ttctgattgg aaacgctgtc
    19021 cgaaaacaat tttcataatt tggtcgaata tcatgacaaa gacattaaaa tgtgttaaaa
    19081 taagatcgta tgagcaattt gctctaacta aaatgaagga gatgtttaga aatgactgca
    19141 actaaacaac ataaaaaagt catcttggtt ggcgatggtg ctgtaggctc ttcttatgcc
    19201 tttgcactag taacccaaaa tattgcccaa gagcttggta ttattgatat ttttaaagaa
    19261 aaaactcaag gagatgctga ggatttaagc catgcgcttg cctttacctc ccctaaaaag
    19321 atctatgctg ctgattatgc tgactgtcac gatgctgacc tagttgtttt aacagctggc
    19381 gctcctcaaa agccaggtga gactcgtctt gaccttgttg agaaaaatct acgtattaat
    19441 aaagaagtgg ttactcaaat tgtggcctca ggctttaagg gaattttcct tgttgctgct
    19501 aatccggtgg atattttgac ctattcaacc tggaaattct caggtttccc taaggaacgc
    19561 gttatcggtt ctggaacatc acttgactca gcacgcttcc gtcaggcact tgctgccaaa
    19621 attggtgtag acgcacgttc tgttcatgcc tacatcatgg gtgagcatgg agattcagaa
    19681 tttgctgttt ggtcacatgc taatgttgca ggggttggat tgtacgactg gcttcaagct
    19741 aatcgtgacg ttgatgaaca aggcttggta gacctcttta tctctgtacg tgacgcagct
    19801 tactctatca tcaataaaaa gggtgctacc ttctatggta ttgcagtcgc cctagcacgt
    19861 attacaaaag ctatccttga tgatgaaaat gcagttcttc cactttctgt tttccaagaa
    19921 ggccaatacg aaggcgttga ggattgctat atcggtcagc ctgctattgt tggtgcctat
    19981 ggtattgttc gtccagtcaa tatcccattg aatgacgctg agcttcaaaa aatgcaagct
    20041 tcagcaaacc aattgaagac tattatcgac gaagccttct ctaaagaaga gtttgcgtct
    20101 gctgctaaaa actaattaaa aaatgaatgt gttagatctt gctctaacgt tttggaatca
    20161 ctacaaaaag cctaatccaa tcggataggc ttttttcatg cgtctaacag cgaggtgcaa
    20221 gacaaagcac gctttcatta agcatcgtgt gtgctatgct tatagtctta agtcacaaaa
    20281 aagacaacca gctttatgag ctggctgctt attagcttgt tattcagcac caagtgctgc
    20341 cattgtaatg tagttatatg gcttgttaaa gtgcggtaag aagaaaatat cagtcaaagc
    20401 taatttctca atggtcactc cttcttggat agcaagtgag aacatatgaa ttcccattga
    20461 aatatcttca tgtgaggcca tttgagcacc tagaatacga cgtgattctt tatcgtagac
    20521 aatcttaatg gttacttgga agttaccatg ctcgataaat tctggttttt gattgtcagt
    20581 gtattctgtt actgctgcat caaagccaag gcattttgct ttctcaagag ttaagccagt
    20641 tgataccatg tgcaagccgt agatagagat accatttgat ccctgcacac caataccctc
    20701 aagagctgtg ccacaagcgt tatgagctgc gacaatccct gtacgaacag catttgaagc
    20761 aagggcaata taattggtat cgcgagttgc gttgtcatag atggttgcac aatcaccgat
    20821 tgcataaatc cctggaatag atgtttcttg gtgtttgtta acaaggaagg caccattacg
    20881 gaaaagctca atcttgccag caccaagagc tgtatttgga cggaagccaa ctgcaaggat
    20941 aaccatatca acaccatatt cattcttatc agtgattagc ttttcaacct tgccatcacc
    21001 agcaacctct ttgacagttt ccccaaaggc caactgaata ccatgctctt ctaggttttt
    21061 agacatgaca tctgtcaaat cacgatcata gtagcctgct agacaagtat ccgcaacatc
    21121 aatcagaata acctctttgc ccttacgttg gaaggcttct gcaagctcta caccaatgta
    21181 gcctgcacca acgactgcaa cgcgcttaat gtctttgttt tctaatttcg aaatgacatc
    21241 tgctgaattt tggtacaatt taacgaattg aagattttca agtgttgctt caaactctaa
    21301 tgagccctct ttgatttctg cacctttaat tggtggcaag ataggctgtg aaccagttgc
    21361 aaaaattaat ttgtcatatg actcaacatg ctctttgcca tcaacaaggg ctgtcactgt
    21421 tttagcatcg tagtcaatag attgaactgg tgattccatg taaaccttag caccaaggga
    21481 ctctagctct tccttatttg agtagaataa gccctctggg ccagaaattt gttcgccaat
    21541 ccaaagtgcc ataccacagc ctaagaatga aatatttgag ttttggtcaa atacaacaat
    21601 ctcattagca tcaccatagt ttgttaacat agtcttgata catgccgtac ctgcgtggtt
    21661 tgcaccgata acaacgattt tactcatatg attatgttcc tcatttcaca atttatatta
    21721 ggtctctatt ataacacagg gaaaaagcgc ttccaactaa aatgctcatt tttcttgctt
    21781 ttttataccg ttttttagtc aataaataag acagcctatc atttgttgaa gggtcgtaca
    21841 aagaccggtt tgcttcagtt aagtcaagac gacattctta ttcaactatt ttcccaaatt
    21901 cattacatga ttaagaccat tttttgtcgt taacttctaa aaaagactca taagctcaat
    21961 caggtaaaga ttgacatgta cctcttgagc ataataaata ttgccgccgt tgcaataaag
    22021 ctttccacca gagaggaggg ctaaggggtg gtaataaaaa taggtttttc cagtagtatt
    22081 tcctaggctg ggtgcaacga cagttctaga atagttagtg gctagttcaa ttgtatgctg
    22141 accgccattt ttagcaacgt aatcaatata ggcggttcca aaattgtaag cttgaacagc
    22201 tgtccaaggg tctacgccgg ctttttctgc taaagctaaa ttgtgagata gcaatctgac
    22261 accatactca atgctagatt gactatcggt gatcgaatcc cttatgccag agctgctttc
    22321 gcttgactgc ataacgtcag cttctcctcc cttagtttcc gtgtatatca tggctagtac
    22381 cagatcgacg tctgctttgt taccgttttc tgctaaaata cgctctactg ttggcttgta
    22441 ttgtaggact ctgtgcacat tcttatgaat ggtaactgct tcgtacaggc aaaaaatgag
    22501 gacggctaat cctaagatac gctttaacac tctaaacatt tagttatttt tgatatcctc
    22561 tatatttttt atcaatatgg aataggttcc gttgtcattc aagataaact ctactgactc
    22621 agcatcttga taaactgcat tagggacaag aagctcaatt ccatttgaca gcgacagctt
    22681 ttgcgtctct agctttttta gctgtctaga atgatcaata tcactgacct gaattggttc
    22741 gggaatcatt tccttgacct gatccacaaa ggttaacctt gcagtcaggt tctggtcaaa
    22801 taattgatct gctagctttt ctggagatag agctgtttct tcttctagat ttttagccag
    22861 tgctactttc atctttgatt gaaaagcaaa gtcatcttgg ttaaaattct cggcaacctt
    22921 ttgagcggtc tgctcaagca tttgaataga ttttttgaca gattgctcag gtgttacctt
    22981 tagcagcttc tcagaaaagt aatgagcaaa gcttccattg tgcttcatgc gtttttcgat
    23041 taagtagtaa tagcctgttt gacggttaat gaccaaggct tcatcaggtg cctgagtagg
    23101 gcttggcaaa ttattttgcg tgatcgtaat aggattttca tgatcgtctg atagatgggc
    23161 aaaatgctct tttagggcaa tgcgtaaaaa ggccagataa ggcactcctt ccttatcaaa
    23221 ctgaataaaa accaaatcgt ttgtcttttg atgttcagaa gcgacaaatt cttccttcca
    23281 aagcttggca attgttactg atgtttccaa aagctctgta ccgattgtgg taaaaaaagc
    23341 atgatcagct tctaattgcc cacgtttagc gtcgtcagaa aaaaccttgg ctaatttttt
    23401 gcgaaaatac tcatcaattc ttggtgttat agctactaaa gcatctgata agatcagctc
    23461 ggtatcgttt ggtgtgaatt ggtggatcac aattcctttt atataaatat ctagcattgt
    23521 tagttcttct tgtataatgg gaaggcgtca gtcaatcggc gaacctcata acggacctct
    23581 tcaaggattt caggctgctg gtggttaacc aaggccttga taattaaatg agcaatagtc
    23641 ctactttcgt ctactcccat tccacgactg gtaatggcag cgcagcctat gcgaatgcct
    23701 gatgttttaa agggagatag ggtctcaaaa ggaatagcat ttttgttaag ggtaatatta
    23761 acctcatcaa gcaaggcttg agcaagcttg ccattttcaa tcaccttagt cacatcaaca
    23821 aggaaaagat ggttatctgt accgcctgag atcagacgaa aacgatcatc cttggcaaaa
    23881 acctctgcca ttgctgctgt atttgctata acagcccttg catagtctgt aaaggcagga
    23941 tcaagcgcct ccttaaacgc aacagccttc gctgctatga catgctccaa aggcccaccc
    24001 tgtagaccag ggaaaatagc tgcattcatt ttccttgaaa ttgcttcatc atttgtcaaa
    24061 agcaggccac cacgaggacc acgaagggtt ttatgagtgg ttgaggtcac aatatgagca
    24121 taaggtactg gattttgatg cagacctgct gcaaccaagc ctgcaatgtg tgccatatcc
    24181 accatcaaat aggatcccac ctggtctgca ataaaacgaa attgctcaaa atcaatctgc
    24241 cgagaatagg ctgaggcacc tgcaacaatc aacttaggct gaacagcctt agcttgcttt
    24301 aggatagctg cgtagtccag cttttcagtt tccttatcga cagtgtagcc gacaaattga
    24361 taggtttttc cagaaaaatt gacaggtgag ccatgtgtca agtgacctcc agctgccaaa
    24421 tccataccaa gcacagtgtc accagcatta atcagtgcca tataagcagc agcattggcc
    24481 tgactaccag aatgaggctg aacgttggca taggctgcac caaagagctt tttggcacgc
    24541 tcaatagcaa ggctttcaac aatatcaaca tactctgtgc cgccataata acgcttgctt
    24601 ggatagccct cagcgtattt gttggtcaag acagagcctt gtgcttgcat aacagccttt
    24661 gagaccatat tttcagaagc aattagctca atattatgct cttgcctgtc ctcctcggcc
    24721 tgaatagcct cccaaagctc ctgatcatag tctttgtagt tctcgttgtt aaacatcatt
    24781 attgtctcct ctataatagc ttcataaatc gtaattgtgt cttatcatct acatagctca
    24841 gcttacggta aaaggcatgt gcctcggtcc tgtgactagc agaattaagc cgaataaagc
    24901 ttactttctc ctgcttagcc ttctcctcta aagcagctag taagcgacga ccgatacctc
    24961 taccttgatg gtccagcctc actgctaagg ccaaaatatt aaagcctttt tccgagtaaa
    25021 gcgactcgta gcattcagca tgcagatagc ctaagagcag attggtctta gtatcagcat
    25081 agcccagcaa ataatgatgc ttatcggatc ttagtttttc caattggctt tttgtcaatt
    25141 caagagaaac cttgtacccc aaggattgat cattaatgtc acaaatagct tgacaatctg
    25201 tttgatctag tggtcttagc atagccttac ctcctctaaa atggcagctc tggaacctta
    25261 gctaataatt gctccttagt aatagcacct tgtcgtaaaa tactgacctt aggtgacgat
    25321 aaatccaaaa tagtagaatc cttccctgtc aaataggcat catcagcata accatcaacc
    25381 tttccatcaa atgccttgac aatgtcatta aagcattttc cactctttga gcctgacagg
    25441 ttagcagatg gcccaatcaa gggacccgtt gctctgataa ttttagctgt gagagggtga
    25501 ctgggtagtc gaaagccaac tgtttttagc ccagaattaa tccaataggg tgtctgggca
    25561 ttggctttta ggataatcgt aagtggacca ggtaaaaaag cctcgtacag cttgttaaga
    25621 taggcaggct gctgcttaga aaaagccaaa atactctcaa aatcagccac attaaggttc
    25681 atagccttgt cgcgaggcct ttttttgaga cgataaacag cattaacagc ctcttcattt
    25741 aaggcctgag caaaaagacc ataaactgtc tcagttggta aaataagagc tccaccagcc
    25801 ttaattgtct ctatcaaatg tgttatcatc aacaaccacc attctttctt tacccagcat
    25861 atccttaagc actctgatac gcttttgagg gaaacgcttg gataagagcc tttttaagcc
    25921 ttctccctgc ttgtagccta tttcaaaata gagcttacca cttgtcgtca gataagcact
    25981 agcttgttcg ataatgcgtc ggtaaataga aaagccattt tctgcagcaa ataaggccaa
    26041 atgcggctca gattgataaa cattcaagcc aacctcgtcc ttatcctcat aggcaatata
    26101 gggagggtta gaaacaatga tgtcaaactg ccctgatagc ttgctaaaaa ggtctgactg
    26161 ctcaaaggct atctctacat gatgatctaa agcgtttgag taagcaaggc tcaaggcatc
    26221 agctgaaata tcagaggctg tgacctgcca gttaggtctt gcttttttta aagcaattgc
    26281 aatagcacca ctgcctgttc caatgtctaa aacggatttg cgagtagcgt cattttcctt
    26341 caagataagc tcaactaatt cttccgtctc tggtcttggg attagcacgc gcgaatccac
    26401 tgcaagcacc agatctctaa aataagccct gcctgtgata tattgtggcg atacatgctg
    26461 gctaagcgct aaaaaaatcc gctctaataa ggcttgatcc tctgaagtga cctcttgatt
    26521 ttgatgaagc aaaaagtcaa ggcttgtcca ctgctttaat tctttaaaaa cataggcgag
    26581 gttttcacga tcctcaccta tgttttctag cctgtcttcg taggctctta gttgcttagc
    26641 atagttcatt ggttatttag cgattctaat ttctgagttt gatcatatag cactaaagcg
    26701 tcaacaatct cgtctaactt tccagacaaa atggtgtcta atttttgcag ggttagaccg
    26761 atacggtgat ctgtcacacg attttgtggg aaattatagg tccgaatccg ttcagaacga
    26821 tcacccgtac cgatagttga tttacgctct gcgtcctgct cgtcctgtgc gatctgtgca
    26881 aaatgatctg ctacacgtgc ccgaataatc ttcatagcct tgtcacgatt cttttgctgc
    26941 gttctttcct cttgcatctc aaccttgatg tttgttggga gatggacgat acgaacagcg
    27001 gttgccacct tgttgacatt ttgtccgcca gcaccagaag catggtaaat atcaatacga
    27061 aggtcctttg gatcaatgtc gtactcaact tcttctacct ctggcatgac taagacagtc
    27121 gcagttgaag tatgcacgcg cccttggctt tctgttacag gaacacgctg tacgcgatga
    27181 gcacctgatt cgtattttag cttggaataa acagattgtc ctgaaaccat agcaacaacc
    27241 tctttaatcc ctccaacacc attataggaa gcctccatta cctcaaagcg ccagccttgg
    27301 ctttcggcaa atttttggta catggctaag agatcaccgg caaatagagc agcctcatca
    27361 ccacctgcgg caccacgaat ttccaagata atatttttat catcatttgg atctttggga
    27421 agcagcaaaa gctttaactt gtcctcatag gcttccttgg cagacttggc ctcttttagc
    27481 tcctccttgg ccatctcttc aatgtcagga tcgccgccgg cttccttaat catctcctca
    27541 gcgtcatcaa tggattggat aatagcctta tactgacgat aagctgctac tgtttctcgt
    27601 gtgctagcct cttcctttga cagagccata aaacgtttgg tgtcagaaac aacctccgga
    27661 tcacttaata attcgcctaa ttcttcataa cggtcctcaa cagcctgtaa ttgatcataa
    27721 atattcatta gggggtattc tctcctcttt ttacttgttt tagttgttat tagattggtg
    27781 ggtgaaaata atgcttgcga caaactggaa tataggtctc attgccacca atttgaatct
    27841 gtgctccctc ataaacgggc ttaccatgtt ctgttcgcaa taccatagtt gcttttttgc
    27901 tgcaatattg acagatggtt tttatctcat caatcttatc agctaacagt aacaggtatt
    27961 tggagccttc aaacaattca ttttgaaaat cattttttaa gccaaaggcc atcactggaa
    28021 catttagctc atcaaccaca cgtgctaaat catagacatt ttgcttgctt aaaaattgac
    28081 attcgtcaat caagacgcaa tagggcttct cctgcaattc agcaataaat gcaaaaatat
    28141 ccatatcatt cgaaattggt acagcctcac gacgcatgcc aatccgacta gaaacaatgc
    28201 caaagccatc acgtgtgtct agcgcacttg tcataatcac aacaggcttc ccctgttctt
    28261 cataattgtg tgctaccttc aagatttcaa tggtctttcc tgaattcatt gttccatatt
    28321 tgtaatataa ttgagccaaa atggagattc ctaccttctt cttttgtcct acttattcta
    28381 tcatatttgt ccctatttgg cgattgcctt atctgaaaat cttattttca caacagctaa
    28441 atcctgtgct gttgagctaa ggttaggctt tttgaagctg acatgctaca atagaggtat
    28501 cattaaaaaa aggagattga ctattatgcc atttgtaacg attgacctgt ttgaggggcg
    28561 tagccaagaa caaaaaattg ccctagcgcg tgaggtgaca gaggttgttt ctcgtatcgc
    28621 acaggctcca aaagaagcga ttcatgttgt aatcaatgac atgcctgagg ggacctattt
    28681 cccgcatggt gagatgaaaa ccaaagccta atgcctaagt cccacttatc taggtgggct
    28741 tttcctattt gaaaaggagg gcctgatgat agctactgat cagatcaaga tgatgggaac
    28801 aatcattgat atttgcattg actcatcaaa agcaaagcag caagcagcta ctatccgaga
    28861 gctactaacc ctttacaatc accgtttttc ggccagtgac gacagctctg aattaatggc
    28921 aatcaaccat atggcaggta ttcagccagt gcgtgtgcat tcagatttgt ttgacttaat
    28981 ctcaatcgga aaagagcata gcttggctta tccaagcaac cttaatatca cacttggtcc
    29041 tttagtgcaa agctggcgca tcggcttttc agacgctaag cttccagatg aagcaactat
    29101 tgatcgcaga ctaagactaa ccaatcctaa tcatatcatc
//
LOCUS       DARYLD010000027        28825 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYLD010000027 DARYLD010000000
VERSION     DARYLD010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28825
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..600)
                     /locus_tag="TU651_001022"
     CDS             complement(<1..600)
                     /locus_tag="TU651_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0897031.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TU651_001023"
     CDS             1005..1649
                     /locus_tag="TU651_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897032.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TU651_001024"
     CDS             1654..2403
                     /locus_tag="TU651_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0897033.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU651_001025"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TU651_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0897034.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU651_001026"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TU651_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL0897035.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TU651_001027"
     CDS             3125..3955
                     /locus_tag="TU651_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897036.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TU651_001028"
     CDS             4015..5295
                     /locus_tag="TU651_001028"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL0897037.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TU651_001029"
     CDS             complement(5500..6792)
                     /locus_tag="TU651_001029"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0897038.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TU651_001030"
     CDS             complement(6782..7498)
                     /locus_tag="TU651_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897039.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TU651_001031"
     CDS             7752..7976
                     /locus_tag="TU651_001031"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897040.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TU651_001032"
     CDS             7987..8907
                     /locus_tag="TU651_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897041.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TU651_001033"
     CDS             8894..9634
                     /locus_tag="TU651_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897042.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TU651_001034"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TU651_001034"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL0897043.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TU651_001035"
     CDS             11532..12479
                     /locus_tag="TU651_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0897044.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TU651_001036"
     CDS             12495..13376
                     /locus_tag="TU651_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0897045.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TU651_001037"
     CDS             13520..14434
                     /locus_tag="TU651_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL0897046.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TU651_001038"
     CDS             14606..16000
                     /locus_tag="TU651_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0897047.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TU651_001039"
     CDS             complement(16048..17739)
                     /locus_tag="TU651_001039"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL0897048.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TU651_001040"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TU651_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL0897049.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TU651_001041"
     CDS             18455..18805
                     /locus_tag="TU651_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL0897050.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TU651_001042"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TU651_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL0897051.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TU651_001043"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TU651_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL0897052.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TU651_001044"
     CDS             23487..24710
                     /locus_tag="TU651_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0897053.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TU651_001045"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TU651_001045"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL0897054.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TU651_001046"
     CDS             25318..25869
                     /locus_tag="TU651_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL0897055.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..27150)
                     /locus_tag="TU651_001047"
     CDS             complement(26305..27150)
                     /locus_tag="TU651_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0897056.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            27447..28019
                     /locus_tag="TU651_001048"
     CDS             27447..28019
                     /locus_tag="TU651_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL0897057.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            28013..28303
                     /locus_tag="TU651_001049"
     CDS             28013..28303
                     /locus_tag="TU651_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897058.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
BASE COUNT         8375 a         4950 c         6334 g         9166 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac ttcgacacta tctaaaatat aagaaatggg
    26821 aatatcattt ttatttttaa ggtaattgaa gcatttttga cgtaattttt ctaattcagt
    26881 aatatttaca gctgatacct gattataaaa ttggtttaaa atgtcctgcc ttgtgctagg
    26941 atgataagtg ttgcagacat atctaaactc ttccagtgtc atattgagtt ggtttaataa
    27001 aaaaatcatt gtatcaaatt taggaatgac ttgtccgctt tcaatacgag ctagtgtaga
    27061 acgagctaaa aagtctccac agatcttttc ttgtgttaat cctttagatt ttcgtatagc
    27121 ttgataaatt ttaccgtaat cccaacgcat aaaacacctc taaaatgtta ctaaatgcta
    27181 caaaaaaata aaatctacaa tagtatttta taatagcatt tagaaagagt aaaggaggaa
    27241 aatttatgag gagacatcta aaggttgtat tattacttgc agcactattg gcatttattg
    27301 taaatgaggg taattttcca tggtggcctt ggggaccata gtacttaact gattactgtt
    27361 atgttgttgc cattagacta tctagattaa tcaaagagta aaatacaagt agcttagtga
    27421 aagacatttt aagaggagaa aagcatatga agaaacgttt agcatttata ttagttgctt
    27481 ttggtatttt gggatttagt ttaggaaatg aagttttagc tgcagatact gcacctgcaa
    27541 gtgcaactat ggcaacagat agtgatgtga gtttttacaa tggagaactg ttgaaaaaat
    27601 atttggtcca aagtggtgat agattgtatt ttgattatga caaagctatt caagataaag
    27661 tttctgatgg tgtaatagat atgggattcc ttgttgagac aattagtgag gactattcac
    27721 aacaaacgtt tacctctcga aagtatttca aggcaggatg gcagctttat ggtaattatt
    27781 gtggacctgg ccataacgga aatcatttta ctttacctgt tattgatgtt ttagatcaag
    27841 gctgtcaaaa tcatgacagt tgttatcgat ggggagctgg gattggtgca aattgtgaat
    27901 gcaatcgtca gttagtaaat tacattaaag tatatcgacg gtggatgcca gctcatgcct
    27961 tgggggttgc tgatgctatt agagtatatt ttgaaacggt aggtgctatt ggatgttaac
    28021 cttaaaaaat attatcaatc gatactacat gtattatgta ttccttattg ttgtgatctg
    28081 gattgggatg ttttttgtac gatgggatac tactgtggct ggtgtattac tctatccact
    28141 gattatgaag caggtattta tcgtactagg agtagttgcg atgataatgg ccattatttc
    28201 tagaaaaatt gttcttggaa tttttggttt actatgctgt gctgcttttt ggattaatct
    28261 tttcttagct ttctatctat tacctggact tttgggaaat tagcgattaa actgtttttg
    28321 atgttttgaa gatgagaaac agattgtttt tctgtaaggc ttcctgttac ttctcaaatg
    28381 ctttggagta tctctttatc atttgttcac tgttgacaac gttaaaaaga ttattccaaa
    28441 catgggaatt gctgcttcag ggtattcctt gttaatattg gattgattag ttgttattta
    28501 tgcaaaatcc ttagagcatt gctttctcat tcttggttca tttgaataaa atgtaactaa
    28561 aaaaactttg taatcaattc aaattgtcac aagtataaaa gtaaaaaagc gactttgtta
    28621 gtgatctgat attcggaagt cctatcattg ctcgcttttt gttttttgag gttgattttt
    28681 attccgaaat tgttgtgaat aagtgcaatt ttaagctaag aattacctaa aatcttttga
    28741 agattactgc ttagcttcta atacctattt atcggtgtgt tgataattgg agagatagcg
    28801 ggattgtcat atgaaataaa tttta
//
LOCUS       DARYLD010000028        26875 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYLD010000028 DARYLD010000000
VERSION     DARYLD010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26875
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            62..337
                     /locus_tag="TU651_001050"
     CDS             62..337
                     /locus_tag="TU651_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL0897059.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFASPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDIALKEMENWV"
     gene            334..1656
                     /locus_tag="TU651_001051"
     CDS             334..1656
                     /locus_tag="TU651_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0897060.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWSTEIGKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGARLETSQTRFKDKYFVPDKRNGLIIYSWALRDGAEAEIYNKIE
                     DICISMKAKDYLKLPPRTDNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLAN
                     KLLQMANGAIYDDDKTTVAIHDDKLDALENVVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGKIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            1657..1845
                     /locus_tag="TU651_001052"
     CDS             1657..1845
                     /locus_tag="TU651_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897061.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAT
                     VKEKYTREREMKNEQTKI"
     gene            1826..2053
                     /locus_tag="TU651_001053"
     CDS             1826..2053
                     /locus_tag="TU651_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897062.1"
                     /translation="MNKQKFEKLDKVKELLDELKMSEFMAPLLVGDQIMEIINDLHND
                     PGQFGAQVFLPSPDKKYKFVVRICREENLED"
     gene            2078..2263
                     /locus_tag="TU651_001054"
     CDS             2078..2263
                     /locus_tag="TU651_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897063.1"
                     /translation="MAENKTGMMTLPIDYANRALAKEEILDELVEREIVDVDLLIELA
                     EDNPFWMSALNFNRGTK"
     gene            2260..2553
                     /locus_tag="TU651_001055"
     CDS             2260..2553
                     /locus_tag="TU651_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897064.1"
                     /translation="MNTNEKVIDTICHIRHCGDRYDMCQDMRSWVAERNGLIQDLLKA
                     KKQIDRNRIAKRLDRAQKNISDIITKVTGDLWQGSDQVIAEQCFLKVLEEMQK"
     gene            2550..3266
                     /locus_tag="TU651_001056"
     CDS             2550..3266
                     /locus_tag="TU651_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL0897065.1"
                     /translation="MNIKEAKIGDKVWVEGIINSSFSNGGVHVNHAGVDAFYDLERTK
                     IKPDGYAGQSPKYLKNIIAKMRELPEHDRAVWIKGIFKEFGIENDISYYLGHKQGVLQ
                     AKDSLKPEVLQYVADWYEKHKDNLEYYIWEYIAEWDNQEKDDFFVFMNFSAFKPIQTL
                     VNMHQFGYTIKKEKLYTVEIPNPNAKQIALRLEKWVEGKVRIVATYSSNNFTDYMRLT
                     EREIRKDFDWAWQFAEEVTG"
     gene            3263..3679
                     /locus_tag="TU651_001057"
     CDS             3263..3679
                     /locus_tag="TU651_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL0897066.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            3769..4221
                     /locus_tag="TU651_001058"
     CDS             3769..4221
                     /locus_tag="TU651_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL0897067.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            4211..5488
                     /locus_tag="TU651_001059"
     CDS             4211..5488
                     /locus_tag="TU651_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0897068.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGAEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAN
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLPSFFGLDYGFINDPSALLHV
                     KIDDANKKLYILEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWIVDERCVKTIEELENYTWKKDKKTNEYTNEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            5504..7036
                     /locus_tag="TU651_001060"
     CDS             5504..7036
                     /locus_tag="TU651_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0897069.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEKIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDTIYTYEDYN
                     LETKGMRLKDYEGHFFRGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            6996..8444
                     /locus_tag="TU651_001061"
     CDS             6996..8444
                     /locus_tag="TU651_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL0897070.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKVASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKRLKQGFVRGEHPRAMARDLAKR
                     FNVANHRAETLIRTDGTMVINNATARRYLNAGLKYYRDLVRLDDRTTEICRTIAKENK
                     RKLLSELKPGINVAPYHFNCRTTIIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNE
                     HKPQLSLLNEYVKNGTPYKVDGHSVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HIKTPDYLVDGAPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEHIYMIDRRGLDISIIKNKDEVLAVLEKEGG"
     gene            8472..8660
                     /locus_tag="TU651_001062"
     CDS             8472..8660
                     /locus_tag="TU651_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897071.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKEG"
     gene            8665..8922
                     /locus_tag="TU651_001063"
     CDS             8665..8922
                     /locus_tag="TU651_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897072.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKQIMELKSIVQ
                     RNALATNEELATVKAATLDNQSVIKAIGDTVDYIKKNYKRK"
     gene            9099..9668
                     /locus_tag="TU651_001064"
     CDS             9099..9668
                     /locus_tag="TU651_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0897073.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKHEYERTFTRADISKMMAAE
                     RTKWESEQSAAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKANIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            9681..10568
                     /locus_tag="TU651_001065"
     CDS             9681..10568
                     /locus_tag="TU651_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0897074.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            10580..10936
                     /locus_tag="TU651_001066"
     CDS             10580..10936
                     /locus_tag="TU651_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0897075.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAIYESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGAVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            10947..11225
                     /locus_tag="TU651_001067"
     CDS             10947..11225
                     /locus_tag="TU651_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897076.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKSRLIKGLAHHKNSTVIYV"
     gene            11222..11566
                     /locus_tag="TU651_001068"
     CDS             11222..11566
                     /locus_tag="TU651_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0897077.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYSEQQRLLHYRVVSPALYSIYLELGTRKMEAQSFLDPALRKEWP
                     VLMANIKKMFKR"
     gene            11570..11929
                     /locus_tag="TU651_001069"
     CDS             11570..11929
                     /locus_tag="TU651_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897078.1"
                     /translation="MDYSLETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKSRMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            11941..12540
                     /locus_tag="TU651_001070"
     CDS             11941..12540
                     /locus_tag="TU651_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL0897079.1"
                     /translation="MANTKKGTTIEITTGKPIVGKKIFYFIQSVDAPKKSQALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESTGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            12594..13049
                     /locus_tag="TU651_001071"
     CDS             12594..13049
                     /locus_tag="TU651_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897080.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDMDATQIQIIEDMIGRMSNAVS"
     gene            13124..13357
                     /locus_tag="TU651_001072"
     CDS             13124..13357
                     /locus_tag="TU651_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897081.1"
                     /translation="MEGLEYKQLAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            13372..17754
                     /locus_tag="TU651_001073"
     CDS             13372..17754
                     /locus_tag="TU651_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0897082.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNTFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFQKIIIPVASVIDKIRGNLTGFINQTKMQLQNLVGIGKIRSAFAKAATGVDILTQR
                     ASSKLNNLSAIFETVAGKLPRPFGTAFRKIASSVSTLNSSIQSVGGKISNSLGQQVLN
                     PALQSWNNFFSSVSAKASAFANKVSTSLFGRLTSSLANLSSKIGSSLSNGFSRMSSSA
                     ATSLNGISQKFANTSSAGERLKSTVMSIVQAFSLMAVAQKAMHAITGAIDGAVSRVDT
                     MNRFPKTMALFGYSAEQSKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTS
                     LALAFNNAMIGYGATTEGAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAF
                     GFGKNGVQDLKSVLSDGKITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHT
                     AVVKGVAGMISAFDEAAKANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLK
                     QSINIDFSPLGASVKEVFALINIVFGDFAHTGELSEQAFDNLKAKITSLAPKVIALWA
                     VMNPASAISTIMPLLSLFGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLS
                     GLPGVFATAAGRGLSVLGTMTSAMSSLVSLALAAIGPAAILGLVVAGLGLINSQFGAQ
                     IEQLLNTAVTKGPGIIQGLVKGITSKIPVLIASGTQLIAKFANAIAVLLPVIIQAGVQ
                     LITSLVQGIGQNATNLISSAIKIIGSFVSSIASALPQLISVGMELLLNVVNGIVQNIP
                     LIIQQAQQIIDSFGNSLQANLPSIISNGIAILVNLVQGITQMLPTVLQIATQVITSFV
                     SGIVQFLPQLLQGGIQIIISLVQGIIQNLPQIAQSAVQIIQSLASGLTQALPQIIAAG
                     IQLVAQLAVALIKGLPQIISAGIQLIMGLGKAMLGAIPNALSGVWEGIKSGFSSMWDQ
                     ITGKSSTSTAKVSADATVMAMNVGMQTTAMANQANTDTTSMLNSISQNTELANINATS
                     NATQMANNVNAQTGTMSLQGLNDSMSLASGISTNMSVANINATTQAREMASGVNGATS
                     SMNLDAINHTLSLASGVGANMGAASTGATSQAQAMSSGVSNSLASMQSNSTKAASGLS
                     NSVTSEMSSAATSATSSVNRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTA
                     KQSMANLVSSVTSGMSRATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASS
                     AGTIYAIANSIAANVAATIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLG
                     KAYATAVTDQNWGVNSTVSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVG
                     DKIYTAVKEKESREQSKDSYFVFD"
     gene            17766..18608
                     /locus_tag="TU651_001074"
     CDS             17766..18608
                     /locus_tag="TU651_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0897083.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSNVERLLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTIAYEFIGKTSQGLKYNLSFALRTAELP
                     FGETKPKDITLSGGSFAYAGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            18618..20600
                     /locus_tag="TU651_001075"
     CDS             18618..20600
                     /locus_tag="TU651_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0897084.1"
                     /translation="MITFLDHRDIEYGVISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRDVVDGNNADLILDWAENPDIIFDGNGGI"
     gene            20600..21718
                     /locus_tag="TU651_001076"
     CDS             20600..21718
                     /locus_tag="TU651_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL0897085.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            21733..23619
                     /locus_tag="TU651_001077"
     CDS             21733..23619
                     /locus_tag="TU651_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL0897086.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            23631..24068
                     /locus_tag="TU651_001078"
     CDS             23631..24068
                     /locus_tag="TU651_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0897087.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            24065..24676
                     /locus_tag="TU651_001079"
     CDS             24065..24676
                     /locus_tag="TU651_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0897088.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            24688..24960
                     /locus_tag="TU651_001080"
     CDS             24688..24960
                     /locus_tag="TU651_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897089.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            24957..25184
                     /locus_tag="TU651_001081"
     CDS             24957..25184
                     /locus_tag="TU651_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL0897090.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            25301..26635
                     /locus_tag="TU651_001082"
     CDS             25301..26635
                     /locus_tag="TU651_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL0897091.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
BASE COUNT         9005 a         4679 c         6001 g         7190 t
ORIGIN      
        1 aaaagagaaa ataagttgaa aaaaacggta accctgacct ttattgacca aaggaggaaa
       61 gatgaggact gaaaaagaca ttgaaaatta tttgaaaaag aaaacaaaag ggctgtgttt
      121 aaaatttgca agtccaggga cgataggagt gcctgacaga attgttgtca tgaacacggg
      181 aacctttttt gtagaggtca aagcacctgg taaaaaacca agacccagcc aagttgccat
      241 gcacaaaaaa ataaaagagg ctgggcagca cgtttgggtt gttgactcct acgaatcagt
      301 ggacatagcc ttaaaagaaa tggagaactg ggtgtgagac tgcacgagta ccaagaatac
      361 gctaagacat ggatagtaga gcacccttat tgtggccttt tacttgacat gggtcttggt
      421 aaaacgctga caacactatc ggcaatagat gagattcaaa atattttttc cgaggatcat
      481 aagattttaa tcgtagcccc taaaaaagtg gcggaagaaa cgtggtcaac ggagattggg
      541 aaatggcatt ttgatttcac ctactctaaa gttttaggga gtgagggaaa acgaattgaa
      601 gccttagaaa cagaagccga tatctatttg attaatcgtg agaatgttac ttggcttgtt
      661 gaatactaca agactaaatg gccgtttacc tttgtggtta ttgatgagct gtcaagcttt
      721 aagtctagta agtcaaaacg gtttagggct ttgcgaaaag ttagaccgaa agtccaacgc
      781 cttgtaggac taacaggaac cccagcgcct aacagtttga ttgatttgtg gccgcagatt
      841 tatctgatgg acagaggcgc caggcttgag acgagccaga ctcgatttaa agacaagtat
      901 tttgttcctg ataagcgtaa tggcctaatc atttacagtt gggcacttag ggatggtgca
      961 gaagcagaaa tctataacaa gattgaggac atctgtatca gcatgaaagc taaagactat
     1021 ctcaagttac cgccgcgaac cgacaacgtt gtatcagtta agttatctaa tatgaaagcc
     1081 tacaaacagc ttgaagctga tttggtgttg gagtttaagg ataaggagat atctgcggct
     1141 aactctgcgg ttttggctaa taaattactt caaatggcta atggcgctat ctatgatgat
     1201 gataaaacaa cagttgctat acacgacgac aaacttgacg cgcttgagaa tgtcgttgaa
     1261 gaaagccaag gccagccaat cttagttttt taccagtatc aacatgatct tgaaaggctt
     1321 aagaaacgat tccctcaggc tgaagagttg acgtcagttg acaagtggaa ttccggaaaa
     1381 ataccaattc ttctgtgtca cccacagtca gccgggcatg ggcttaatct gcaaaaagga
     1441 gggcatatta ttgtttggtt tgggctaaca tggagtcttg aatattatca acaagctaat
     1501 gccagattag acagacaagg gcagacagaa cccgttattg tgcaccacat tgttgcagaa
     1561 aatacagttg atgaaaaagt acttaggatt ttacaaggca aagaaaaaaa tcagaacgcc
     1621 ttacttgaag cagttaaggc gcagttaggg gtctagatga aaaaagaata tgtcgttaga
     1681 atctacacgg gtagagaaaa gaattttgag gcaaaacctc agtttgaaga gaaaaccttt
     1741 acgcgaaaag cagacatgct gaggttttgg gattcttgcg aagcaacagt taaagaaaaa
     1801 tatactaggg agcgggagat gaaaaatgaa caaacaaaaa tttgaaaaat tagacaaagt
     1861 aaaagaacta cttgacgaat tgaaaatgtc agaatttatg gcgccacttt tagttggtga
     1921 tcagattatg gaaattatca acgatttgca caatgatcca ggacaatttg gagcgcaggt
     1981 atttctgcca tcgccagaca aaaaatataa gtttgtagtg cgaatttgtc gagaagaaaa
     2041 tttagaggat tgagttaacg aaaatgaggg taggataatg gctgaaaata aaactggaat
     2101 gatgacttta ccaatcgact atgcaaacag agcattagca aaagaggaaa tacttgatga
     2161 acttgttgaa agagaaattg tagatgtaga tctgttaata gagcttgcag aagataatcc
     2221 gttttggatg agtgcattga attttaaccg aggtacaaaa tgaacactaa cgaaaaagta
     2281 atcgatacta tatgtcacat cagacattgc ggtgacagat acgatatgtg ccaagacatg
     2341 cggtcgtggg tagctgagag aaatggatta atccaggact tactcaaagc aaaaaaacaa
     2401 attgatcgca atcgtatcgc taaacgtctg gatcgtgcgc agaaaaacat cagtgacatt
     2461 atcacaaaag tgacaggcga cttatggcaa ggcagtgatc aagtcattgc tgagcagtgt
     2521 tttttaaaag tattagagga gatgcaaaaa tgaacattaa agaagcgaaa ataggcgata
     2581 aagtgtgggt tgaaggtatt atcaattcgt ccttttcaaa tggtggagta catgtaaatc
     2641 atgctggtgt tgacgccttt tatgatcttg agcgaacaaa aataaaacca gacggatacg
     2701 cagggcagtc acctaaatat cttaaaaata ttattgctaa aatgcgagaa ctaccagagc
     2761 acgacagagc cgtctggatt aaaggtattt ttaaggaatt tggtattgag aacgacatta
     2821 gctattatct tggccacaag caaggcgtat tacaagcaaa ggattcgcta aaaccagaag
     2881 tactgcagta tgtggcggat tggtatgaga aacataaaga taatttggaa tattacattt
     2941 gggaatatat agccgaatgg gacaatcaag aaaaagatga ttttttcgtt tttatgaatt
     3001 ttagcgcatt taagcctatc cagacgttag ttaacatgca tcaattcgga tacacaatca
     3061 aaaaagaaaa gctgtatacg gtggagatac ctaatccgaa tgctaagcaa atagctttga
     3121 gacttgaaaa atgggttgaa ggaaaagtaa gaattgttgc aacttactca tctaataatt
     3181 ttacagatta catgcgctta acggaacgag aaatccgaaa agattttgat tgggcgtggc
     3241 agtttgcgga agaggtaacg ggatgagtag attatctaat gcacagctaa aggcttttga
     3301 tgaatggttg tttgattatc gttttattga taacaagatt gcacttcgaa aacttgagct
     3361 acaaactgac atgaatacag aagtagataa aaatatcggt ggaggaagag caaattttgt
     3421 ttcaaaagtt actgaggatg tggttgcaag gtgggattca gatagggaac taaagggtct
     3481 atccaatttc aaagaagcag ttattgcaac gctaaatctt ttggatgaag aactaactga
     3541 tatttttaat cttaggtggg gcgtcggttc aagtaacact tgggaagaaa ttgcctatac
     3601 aagacatctg tcgcgtaagt ctatttaccg caaaagagag cggattctag aaatattttc
     3661 caaaaaaata ggaatgtgac acaaaaatgt atggaattgt catctttttg atgataaatt
     3721 ggtagtatga gtttgaaggt aaggcagata gtgtcttgcc tttttgctat gcttggaggt
     3781 gatggaaaat tgagtaaatt aaccctaaaa cagaagcgtt ttgcagatga gtacatcatc
     3841 tcagctaacg cgacagcagc ggctattaaa gcagggtata gtaaaaagac agcaaggtca
     3901 ataggtcaag aaaacttgac caaacctgac attaaagctt atatagacga gcggcttgaa
     3961 aaacttgaat ctgaaaagat tgctacgcaa gaagaagtcc tacaatatct cacttcaatt
     4021 atgcgaggag accaacaaga aaagacgctc attagcgttg gagagtttgg tcagaagata
     4081 gttgacatcg atgttggtgc caaggataga atcaaggcag ctgagctact aggcaaacgg
     4141 tacaggttat ttactgacaa ggttgaaatg gatgtcagct cagatgtaac cattaacgta
     4201 ggtgagtggg atgacgacta aacagcgccc taaaattaat atcgtgatca agcatcctag
     4261 caaagttttt aacaaacata tctacgacaa actttacaac tatagcaact tcacggaagt
     4321 tcattatggt ggggcgtcta gcggaaagtc tcacggtgtt tttcaaaaga taattttaaa
     4381 agcacttaac cctaaattca aacatcccag aaagatatta gttctcagaa aagtcggtgc
     4441 aactgttaga gactctgtat ttgctgatat catgtctaat ttgtcgtatt tcggcatctt
     4501 ggataaatgt aagataaata tgtcggcttt tagaataacg ctcccaaatg gcgcagaatt
     4561 cattttcaag ggtatggaca acccagagaa gattaagtca attaagggta tatctgatgt
     4621 ggttatggaa gaagctagtg agtttacgct tgatgattat acgcagttga ccttgcgttt
     4681 aagagataag aaacatctag agaagcaaat atacttgatg tttaacccgg tatcaaaagt
     4741 aaactgggtt tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac
     4801 aacttataaa gacaaccgct tcttagatga tgtcacgaga gaaaatatcg aggaactagc
     4861 caataggaat gaagcttatt acaaaatata tgctcttggc cagtttgcta cacttgataa
     4921 actaattttt cccaaatatg acaagcaaat attaaacaaa gacaagttat cacacttgcc
     4981 ttcttttttt ggtttggact atggatttat caatgatcct tcggcacttt tgcatgttaa
     5041 aatcgatgac gcaaacaaga agttatacat cttagaggaa tatgtcagga agaatttgac
     5101 caatgacaaa atagcaaatg ctataaagga cctcggctac gccaaagaag aaatcagagg
     5161 agattcggct gaaaagaaat ctaatcaaga gctgaggaat ttaggtattc ctagaatgat
     5221 tgatgttacc aaagggcctg gaaccgttat gcaaggaata cagtatttgc ttcaatatga
     5281 ttggattgtt gatgaaaggt gtgtcaagac tattgaagaa ctcgaaaatt acacttggaa
     5341 gaaagacaag aagactaatg agtataccaa cgaaccagtt gacagctata accactgcat
     5401 tgatgccata agatatgccg tacaagacag aatataccag tcggcggata gaagtaagcg
     5461 catgaaaaat gctaaatatt atttttagga atgaggtgaa actttggaag aaaaacaatt
     5521 tttagcagga actcgtttta atgagaatgc taataagcaa tttattatgc tgcaagaaga
     5581 ctttgaagca attgactatg aatcaaaact ttggatagat caacttaaga attacatttc
     5641 aaggtttaaa gcagaacaat tagagcgttt gaaagagtta aagcgatact atcttgggga
     5701 taataacatc aagtatagac ctgctaaaac agataaatac gcagcggata atcgtattgc
     5761 aagtgatttt gctaagtata ttacggtatt tgagcaaggt tatatgcttg gcgttcccgt
     5821 tgagtacaaa aatgaaaata aagacctcca ggcagctatt gaccttatgt cggtcagaaa
     5881 caatgaggac taccacaacg tcaaaataaa aacagattta tcaatttatg gaagagccta
     5941 cgagctgtta actgttgaga aaatagatga caaaaaaacc gaagtaaaac tctaccagct
     6001 cccggccgag caaacttttg ttatctatga tgatacatac cagcgaaatt cgttgatggc
     6061 cgttcatttc tacgacatag attacggctc aggtaaacgt aaacagatta tcaaagcata
     6121 tacttccgac acaatttata cctacgaaga ctataacctt gaaacaaaag gtatgcgatt
     6181 aaaagattat gaaggacatt tttttagagg tgtaccagtc aacgaatacg ctaataacga
     6241 ggagcgaacg ggggcttatg agtctgtact tgataatatt gacgcctatg atttatctca
     6301 atcagagctt gctaactttc aacaagattc agtcaatgcg ttgcttgtaa tagctggtaa
     6361 tgcttacaca ggagctgatg agaatgacta cttagatgat ggccgattaa atcctaatgg
     6421 tcgtttagcg atctcaattg ggtttaaaaa agcccaagtg ttaattttag acgataatcc
     6481 taatccaaat ggcgttaaac cgcaagcgta ctttctcaaa aaagagtatg ataccgccgg
     6541 tagcgaagcc tacaaaaata gattagttgc agacattttg aggtttactt ttacgccaga
     6601 tacacaagat atgaaatttt caggagttca atctggtgaa tcaatgaagt ataagcttat
     6661 ggcttctgac aactatcgcg agaagcaaga gaggttgttt aaaaaaggat taatgcgacg
     6721 cttacgctta gcagctaata tctgggccat caaagggaat gaagcaacta catatagcct
     6781 tgtaaatgat acgagtatag ttttcacacc taatcttcct caaaacgata atgaaattgt
     6841 tacagctgca caaaatcttt atggcattgt tagcgatcag actatctttg aaatcttaaa
     6901 tactgtcaca ggagtagatg ctgaagcaga gcttgaacgc ttgaaagaag aagctgataa
     6961 aaagcaatct ttaccggagc ctagattggt aggtgatgct agtggtcaag aagaaccaac
     7021 ggcagaaaag ccttaattac tggcaaaagc gtcaaaaaga tattctaagt tatttagaca
     7081 gaactgattt agatgtcttt tcagaactgc agaagttata taatgaacag gcttttgagt
     7141 tacaaaagga attgtttgat ttttatacta agtattctga agagaacaaa atgacttatc
     7201 aggatgtcgt taaaaaacta cgtcatgaag atttatcaga ttacgtagct aatgctaaca
     7261 agtatcgtaa acaagctgag aaagatcctg agctgctaaa acgacttaat gagcagtatg
     7321 tatcagcaag agctacaagg atggatgcat taaatcttga gcttgtttat cgtgcgggga
     7381 tactaaaagg tgtacttgat tcagcatttg aaaatcattt aaaaaaagtt gcctcatatg
     7441 cttataaaaa agcaatgggt ggacggtcag ggacaatcaa tggtccagtt ttagaagaac
     7501 tggttagaac cccgtttgat ggttataact attcagaaca gttgtggggc aatactgaca
     7561 atcttgttaa gaatcttcaa aagagattaa aacaaggttt tgttcgtggc gagcatccta
     7621 gagcgatggc cagagattta gctaagcgat ttaatgttgc taatcacagg gctgaaacac
     7681 taatcagaac tgatggaact atggtgatta ataatgctac cgctaggcgc tacttgaatg
     7741 caggacttaa gtattatcgt gatttagtta gacttgatga caggacaact gagatatgcc
     7801 gtacaattgc taaagaaaac aaaagaaagc tattatctga gctaaagcct ggaattaatg
     7861 tagcacccta tcatttcaac tgcagaacaa ctattattcc tgatgaagat gagctaagta
     7921 ttgaagtaga accaattgat gataaaagca ctaagtattt taaggatgtc acctcagatt
     7981 ggatagatgg aaatgagcat aaaccacaac tgtcactact aaatgagtac gtaaaaaatg
     8041 gcactcctta caaagtagat ggccatagtg tcgttcttga tcattcgaat tatgaatata
     8101 gagttgctaa ttggttatcc aaaaagacag gattgcaagt tgacatggtg ccaagagtta
     8161 attcccctga acatatcaag actcctgatt atttagttga tggagctcct tttgatctaa
     8221 aagaaatcac aggttcgggt aaaaacgtca ttgatggcaa tctacgaaaa gcaaaaaagc
     8281 aggcaactaa tatcattttt gatataacaa aaaccccttt atcatttgaa gagataatgg
     8341 ggcaattaga acatatttat atgatagatc gtaggggtct tgatatatca attatcaaaa
     8401 ataaagatga ggtattagct gtattagaaa aagaaggagg atgacccacc gcctccacag
     8461 taaactgctt catgggcgtt agaccatcat ccttctttat ctcaattata catcacccta
     8521 ttaaaactat caaggaggaa aatatgttta tttggcaaat ggtattagtg gcactaggtg
     8581 tattggtact catattgatt gttggcattg cagcaatagc ggttaagtca attattgcag
     8641 aattgaaaaa agaaggataa aacaatgaat aagcgcatta agaaaaaacg taaattggaa
     8701 acagcggttg tgatgcttgt tgcagagaat gccatgcaag cagaagctat taaaaatcaa
     8761 aacaaacaaa tcatggagct aaaatcaatc gttcaacgaa acgctctggc aacaaacgaa
     8821 gagttagcga ctgttaaagc tgctacttta gataaccaat cagttatcaa ggcaattggt
     8881 gacacggttg actatattaa gaaaaactac aaacggaagt aggggaaata aagtttaacc
     8941 gtgtcgaatt tgacctcttt acaaatctaa accaaagtcg tagcaatacg gctttttatt
     9001 gtgtccaaac tttgttgatg acactaaaag ctacactgtt tcgtcgcagg acgtaaagct
     9061 agactatcgg ttggtggcgt aaccactagg agaaagttat ggcagaagaa aatgtaacaa
     9121 cagagacaac tgagcaagtc gacactcaaa aagaagctgt tgaacatcct aagcatgaat
     9181 atgagcgaac ttttactcgc gcagacatct caaaaatgat ggctgctgaa cgcactaaat
     9241 gggaatctga acaatccgca gctattgaaa aagctcgtac agaaggtgaa cgtttggcca
     9301 agttgtcaaa agatgagcgc gctaaagagg aggaacaaaa acgtctagat gctatcgcag
     9361 agcgtgaaaa agcagtagca gagcgtgaga tgcgcattga gacgcattcc ctgcttgtgg
     9421 agaaaggatt gccattggat tttattgata ttgttttagc cactactgca gaagaggtta
     9481 aggccaatat tgataattta caaactattt ttgataaagc tgttgaaaaa cgtgttaacg
     9541 atcgtttaac tcagaaaccg ccacgaactg gaaatggctc ggtcggtatg actaaggctg
     9601 acatcatggc gatagaggat gacgacgaac gtatgcgttt aattgctgag aatcgtaact
     9661 tattttaaga ggggaatatt atggctgaaa aaaacttaaa cactatggcg gacttaggag
     9721 atattaaatc aattgatttt gttaacaagt tttccaaaaa tattaatgat ttactaaaat
     9781 tgctaggggt tactcgtcgt gaaacattaa ctaacgatct aaaaattcag acctataagt
     9841 gggaagtgac tttagatcaa actgatcctg gagaagggga aacaatccct ctgtctaagg
     9901 ttactcgaac taaagataaa gactatacag tgaagtggtt caagaaacgt cgtgcaacta
     9961 cagctgaggc aattgctcgc catggtgcag ctcgtgctat tactgaagca gataagcgca
    10021 ttatgcgtga gcttcagaat ggaattaagg atgcattctt tacattcctc aaaacaaaac
    10081 caacaaaagt taaaggcgtt ggccttcaaa aagcgctgtc tgcatcatgg gctaagctag
    10141 ctacttttaa tgagtttgag ggttccccgc ttgtttcttt tgtctctcct ttagacgtag
    10201 ctaactatct tggagatact aaagtaggtg cggatgcctc taatgttttt ggaatgacat
    10261 tgcttaagaa ctttttgggt atgcaaaatg tgattgttat gccatctgtg ccagagggta
    10321 aaatctactc aacggctgta gaaaatctag tttttgcatc tttaaatgtt aaagggggag
    10381 acttgggcgg cttgtttgct gattttactg atgagacagg tttaattgct gcagctcgta
    10441 atcgtcagct ttctaatctt acctatgaat ctgttttctt tggggcgaat gtactgtttg
    10501 ctgaaattcc tgaaggggtt gtagaggcaa caatcgaagc tgctgctgta cccggcattg
    10561 gtggttaaag gctatttata tgggtgataa acaacttatt gacgatatca aactctttat
    10621 aggtatttcc aagggtgatg gtgcgcaaga tgagctcatc acccttgcta tatatgaaag
    10681 taaagagcgt gtgctagcta aacttaatga atactcagaa actgaaatca ccaaaattcc
    10741 tgatagattg aggtttattg tccgtgatgt tgctattaaa cggtttaata ggattaattc
    10801 agaaggagcc gttgaagata gcgaagaagg aaagactttt aagtgggaca gttaccttaa
    10861 agagtatgaa tcaacactca gaagcgctgc tattgggaag gtatattcag gcaaaggggt
    10921 agcaagattt atttaggaga tacacaatga tctataaaga tagagtaatc ttagtgtatg
    10981 tcgatgaaca ggacgatttt ctagataaaa gaactgttga aaaacctagc gggaaaatcc
    11041 cctgtatgga aaatactttc acaaaatctg aacagatggg gctatttggt aaatatgatt
    11101 tgaatgcttt taagttgcac ttgcaaggcc attacgacgg ctttagcaag attatctaca
    11161 agggaaaatc gaggttgata aagggactag cacaccataa aaatagcacg gttatttatg
    11221 tatgagtctt atttatcgga tgagaggcct agataggttt ttacgcagcg ttgagcgcaa
    11281 gcagaagtca gtacgaatcg ctgtagataa agagcttagt aaatcagctg ctaggattga
    11341 gagacaggct aaaatactag ccccggttga cactggatgg ctgagagctc aaatctacag
    11401 tgagcaacaa cgactcttac actatagagt ggtttctcct gctttatatt ctatttatct
    11461 tgaattaggt actcgtaaaa tggaagcaca atcgttttta gaccctgccc tgagaaaaga
    11521 atggcctgtg ctaatggcta atatcaaaaa aatgtttaag aggtgatgca tggattactc
    11581 actggaaaca ctatatttaa aaaaggtaaa aaatagattg ggagttttag acataccaat
    11641 ctattttaaa ttgcctaaat cagacgtttt agagcctttt attgttgtag gtacaaatat
    11701 atcagacttg tcaaaaacag ctcaaactgg agcagttatt gatgatttta gcctgaatat
    11761 cgatgctttc ttacctggcg atagtcgttt ggatgcagaa gagataaaat ctcgcatgct
    11821 tagactgctt gggcgaaata accaaataaa ggctcagatt ttggtagata attcaatagg
    11881 acgagaagtc tatagagttg ctatcaacat tacagaaaca ctattttaaa ggggacctaa
    11941 atggcaaaca caaaaaaagg aacaactatt gaaattacaa caggtaaacc gattgtagga
    12001 aaaaagattt tttactttat acaatcagtt gatgcaccaa agaaaagtca ggctctgttg
    12061 ccagcctatc gtaccgatgg tactacaacc atgggtggtg aatacattga tgagcaaacc
    12121 caacaaggtc gcgttattga gaaggctaca gatgaacact ctattgattt gacaacgtac
    12181 tttgtaccga cagatccatc tgttgctgtc atcgaggaag ctaagaaaac aggtaaatct
    12241 atcaaaattt gggaagttat tgccgacgaa agtgtcaaag aacagattca aattcctgaa
    12301 tcgactggac ccaagaaaga tgtttaccct gctaagtttg ggtacgccaa gattgacgaa
    12361 atcgaacgcg gtactggtat ttcagactta gtagaaatgt cctacaccgc taacattgta
    12421 ggggccttac aagatggtaa attccctctc acgaaagaag aaattgaaat gctagaaaat
    12481 gtatacggct atcaaaatcc gggtgatact actggcgact acgataatat cactaaatag
    12541 cacacagggg tggcaactgc taccccattt tgatttaaaa aggagataaa ataatggaat
    12601 ttacagcagc aaaacgaaat atcgatatta aatttgattt taaaactatg tttaagatca
    12661 ataataaact aggaacaatt aacccagaaa caggagagcg caatgcagat ggtgtgggtg
    12721 ctttgttttt caatatctta gagcgtaatg aaagcgccat tgttgacctt gtgcgtttat
    12781 ctgcgggaag cggaaaaaaa gcgctaactg aagatgaaat tctagatgca attgcagaag
    12841 ctgttgatga agaaggaaca acagaagggt tgtttgctga gattgaaaaa gaaatggttg
    12901 attctggttt tttcagagcg aagattttga aatatatcga aaacatggag aaatcagctc
    12961 gttatctcaa agcgaaggac gatatggacg caactcaaat ccaaattatc gaagacatga
    13021 ttggaagaat gagcaacgca gtatcttagt aaattgcgca cggctagggc tcacagacat
    13081 tgatactatc tataaatgta ctaagtggga gctagaggct attatggagg ggcttgagta
    13141 taagcagctt gctgagcgcg agaacctctc tgaattgtct ctaaagctta gatatacatt
    13201 aaatgctaaa aaggttgatg taggtaagct caaatacgat aagcataggc taactatcaa
    13261 aagatcgtat caaaaagcta gccgtagcca agccgatagt gatagcagta ttgttgagag
    13321 aatacaaatg cttaataatc attttcaaaa tagatagata aggaggagta gatgccagga
    13381 acatttgatg gttctatttt cgctgatgtt ggtgccaaca caaaggacta tgagcaggcc
    13441 atggctcgta ttgttagtac gactcagaat actttcagaa aagcccaaga tacagcggtt
    13501 aacagtagta ataaaatggt tcaaatcatt ggacaaatca tggcccaact ggcgaacaac
    13561 ggcgaatcgc tcgggaagag acttggctct gcctacgcta ctggtttaaa actgagcatt
    13621 ggtgaaattc aacgcatagc agcttccatt ggcgaaaaaa ttcccgaacc cataaagaat
    13681 ggttttcaaa aaatcattat tccagttgca agtgttattg acaaaatacg gggtaactta
    13741 accggtttca ttaatcaaac aaaaatgcaa cttcagaatc ttgtgggtat tggtaagata
    13801 agatctgcat ttgccaaggc tgcgactgga gttgatatct taactcagag ggcaagtagt
    13861 aagcttaata acttatctgc aatattcgaa acggtcgcag gcaagcttcc gcgaccattc
    13921 ggaacagcgt ttagaaaaat tgcctcatcc gtttctacct tgaatagctc tatacagtct
    13981 gttggaggga agatttctaa ttcacttggt cagcaagtct tgaacccagc cttacagtca
    14041 tggaataatt tttttagttc tgtatcagct aaggcgtctg ctttcgcaaa caaagtgagt
    14101 actagtttgt ttggtcggct gacctcaagt ttagctaatt tatcaagtaa aatagggagc
    14161 agtcttagca atggttttag cagaatgtct agttctgcgg ctacttcctt gaatggaata
    14221 agccagaaat tcgccaatac ctcttctgct ggagagagac tcaaaagtac agtgatgagc
    14281 atcgtgcagg cctttagttt aatggctgtt gctcaaaaag ctatgcacgc tattactggg
    14341 gcaatagacg gggcggttag tcgcgttgat accatgaacc gctttccgaa aacgatggcg
    14401 ctatttgggt attctgctga acaatctaag gcatcaattg ataagctatc aaaaggaatt
    14461 gaaggtctgc caactcctct agacagtgct gtaaaaagcg ctcaacagct cgccataacc
    14521 acaggaagtt tagataaagg gactagttta gccctcgcct tcaataacgc aatgatcggt
    14581 tacggggcaa caactgaagg ggctgagcaa gcactcaggc agtttaacca gtcgttgggg
    14641 tctggaaaaa ttcaagctga agagtttaac tctgtatcag aagctgcgcc aggtttaatg
    14701 tctaaaatgg cggaagcctt cggttttggt aaaaatggcg tacaagattt aaaatcagtc
    14761 ttatctgatg gcaaaatcac tgcacaagag ttcgcagata aaatgattga gcttaacgat
    14821 gcccaaggcg gatttgcaga gatggcccaa tcatcggctg gtggaatccg aactgcatgg
    14881 aagaacgtac ataccgccgt cgtaaaaggc gtagcaggta tgatttcagc ctttgatgaa
    14941 gcggctaaag ctaatggcat gaagaccatt gctgaaacac ttcttagtct gaagccagca
    15001 ataaccagtg tttttgatac gattaattct cttattccaa atgcagttgc agcattcgct
    15061 aggctaaaac agtctatcaa tattgacttt agcccattag gcgccagcgt taaagaggtg
    15121 tttgctctta ttaatattgt ttttggagat tttgcacata ctggtgaatt atcagagcag
    15181 gcttttgata atctaaaagc aaaaatcact tctttagctc ctaaagtcat tgccctttgg
    15241 gcagtgatga accccgctag cgctatatca acgataatgc ctttgctttc tctattcgga
    15301 aaagttggtc tagctttagg aagcttaggg acttctgtcg gggcgtttgg cggcataatt
    15361 tctagtggga tagctagtgc cagcggcgtt gttggtgcct ttgcggcaac tctaagcgga
    15421 ttacctggcg tttttgctac cgcagcaggg cgtgggctat ctgtgcttgg aactatgaca
    15481 agcgcaatgt ccagtcttgt gagtttagca ctggcggcca taggaccggc cgctattcta
    15541 ggtcttgtgg tggcaggact tggtttgatt aatagtcagt ttggcgcaca aatcgagcag
    15601 ctacttaaca ccgcagttac aaaaggtcct ggcattattc aaggccttgt aaaaggaatt
    15661 acttctaaaa taccagtttt gatagctagt ggcactcaat tgattgctaa atttgcaaat
    15721 gctatcgcag tgttattacc agttataatt caagctggcg ttcagctaat tacgagtctc
    15781 gtccaaggta ttggacaaaa tgcaacgaat ttaattagtt cagcaataaa aatcattggt
    15841 agttttgtta gttcaattgc gagtgcattg ccgcagctta tttctgttgg aatggagcta
    15901 ttattaaatg ttgtcaacgg catagttcaa aatatacctc ttattatcca gcaagcccag
    15961 caaattattg atagttttgg gaatagttta caggctaacc ttcctagtat tattagcaac
    16021 ggtatagcta ttttggtgaa tcttgtacag ggaattactc aaatgttgcc aactgttctg
    16081 cagatagcta ctcaagtcat tacgagtttt gtatctggaa ttgtacagtt tttaccgcag
    16141 ttacttcaag gtggcattca aatcattatt agccttgtgc aggggattat tcaaaatcta
    16201 ccccagattg cacaatctgc tgtacagatt atacagtctt tagcttctgg actgacgcaa
    16261 gctctacctc agattatcgc agcaggcatt cagcttgttg cgcaactagc cgtagccttg
    16321 ataaaggggc ttccacagat tatttctgcg ggtattcaat taattatggg gctcggtaaa
    16381 gccatgttag gggctatccc aaacgctctt tcaggagttt gggaaggtat taagagcgga
    16441 ttcagttcga tgtgggacca aatcacaggt aagagttcca caagtacagc taaagtctct
    16501 gcggacgcca cggtcatggc catgaatgtt gggatgcaaa cgacagctat ggctaatcaa
    16561 gctaatacag atacgacatc tatgcttaat agcattagtc aaaatacaga gcttgctaat
    16621 ataaacgcta catcaaatgc cacacagatg gctaataacg ttaatgctca gacaggaacg
    16681 atgagtcttc aggggttgaa tgattcgatg tctcttgcga gtggcattag cactaatatg
    16741 tctgtcgcta atataaacgc tactactcag gctcgagaaa tggcttcagg ggttaatggt
    16801 gcgacttctt caatgaatct agacgccatt aatcatacgc tcagcttagc tagtggtgtt
    16861 ggtgcgaaca tgggagctgc tagcacaggt gcaacttctc aggcgcaagc tatgagctca
    16921 ggggtgagta acagcctggc atcaatgcag tcaaactcaa ctaaagcagc ctctggtctg
    16981 tctaatagtg tgacaagcga aatgtcttct gcagcaacct ctgcaacctc aagcgttaat
    17041 aggttgtcct cggcggtcga gtctggcttc aataaggcga agacttcagc aacaacctca
    17101 atgaatggga tagccaatgc ggttaaaaca ggatttagta gcattaacag tactgcaaag
    17161 caatctatgg caaaccttgt aagttcagtg acttctggga tgtctcgtgc aaccgcggtg
    17221 tctaataatg cttgtcagaa gatcctctca atattcaggg ctttggcagg gcagatgtct
    17281 tctgcaggag cttatgcagg tcaaggtttt gctaatggtc tagctagtag cgcaggcaca
    17341 atctacgcaa tagctaacag cattgccgct aatgtagcag caacaattag acgcgcttta
    17401 gatattcact caccatctcg tgtcactaaa acactaggtg catttactgg agaggggttt
    17461 gccctcggta tggcagagtg gataggtgag atcaatagcc taggtaaagc atacgcaaca
    17521 gcagttactg atcaaaactg gggggtaaat agtactgttt caacatctgc taaagttaat
    17581 aatagtggaa tcaatacctc tcttgataat cttagcgaag aggttaggca gtctcaattg
    17641 tcagagccta tctttgaagt gcataatgag attgttggag ataaaattta cacggctgtt
    17701 aaagaaaaag aatcaagaga gcaatctaaa gattcttatt ttgtttttga ctagaaggga
    17761 gtattttgga tttattaata gaaaaagaga gtcaggcaac taggttgtct gactttggta
    17821 tttataatat tgctattgaa gatagcgctc ctttactatc tgtatcacac cgagcagtca
    17881 aaggaaggag tggttacatc tacgatgggg ctacttttac gactaaaacg cttaaggtca
    17941 aaggaagagt gacggtaagc aacgtggaaa gacttttgga caaacaggac gaactaaacg
    18001 ctctgcttgt tgttgacgaa cctttctacg tgactaagat gtaccctgaa aactcagatc
    18061 tatttaactt tgagcttcca ggggaaagca caggagacct gcaacttatt ggctctcctc
    18121 ataaaccttg gaaatataga tttaaagtca tcttagacga cactatcgct tatgaattta
    18181 taggaaaaac cagtcaagga ctaaaatata atctttcctt cgcgctaaga actgctgaat
    18241 tacctttcgg tgagacaaag ccaaaggaca taactctatc agggggcagt tttgcctatg
    18301 caggaaccgc taaagcaagt cagctagagt ggccttttat tatagagctt actccttctg
    18361 gaggtcagac taatttttat attgaaattg atggcaggcg ctttgagttt aagcagaata
    18421 gccagctaca aaatagtgat aaattacttt tgacaggcat agctaccaca ctaaacggaa
    18481 attatgtcaa tgctaaaacg aactatgagt attttatctt caatcctaat cctaacaaga
    18541 gaattactta caaaacggat tttcttggca cgattaggat tttaaatttt gtagagttgt
    18601 ataaataggg aggtctaatg attacttttt tggatcatcg tgacattgag tatggggtca
    18661 ttagtgtcat taggcatact aatgctgtta atggtgagcg ctcagtgagc ggggaaattt
    18721 atacaaacag tgatgtcctc aataatatcg atagagggtg gcgacttaga tttgaagatg
    18781 agtattacgt tgttatttac gcaaagcctg ttgatgttgg tcaaaaaacg caagtttcgt
    18841 ttgatgccat acaccaattt ttttgggact tcagcaagag tagtatctat gagggtctcg
    18901 gagatgggtc tcataccatt gatacctatc tagagacagt atttaaaggt agtgggtacc
    18961 gctataagct agaagtaggt gtgaacgcat ttagaaaaca atcttttaat tataagtcca
    19021 ggttagattt attcaatgag attattaaag cgaccggact tgaattttca gtcagcggga
    19081 aagttgttcg gctattaaaa aacataggta ctgatctgtc aacagtggta cgaaaaaatt
    19141 tcaacatgaa tgaccttacc attgaaaaga atattgatag ctttattacc tatcagaaag
    19201 gctttggtgc atggaccgac ccagaggacc actctaaggg gagacttgag gcggaatacg
    19261 aaagtcctct tgccaaggag tacggtcgac ttgaaggggc gcctctgacg gatgagcgct
    19321 tcacggtggc agataatcta aaagaagctt taaaaagtaa tgttgaaaat tcatataaga
    19381 tatcagtaaa aattgatatg gaagatttaa cgagagctgg gtatagatgt gagaggccgg
    19441 ttgctggtga ctacattatg gcgataaatg agactttagg ttttcaagag cgtatacgga
    19501 tagtttcttt tacaagctac tacgacgcaa ctggagcttt agtaaaacat gaagtcactt
    19561 gtaatgatat cggatctgtg aaaaaacaaa gcgtaggaag tctgtctata aacagtagaa
    19621 tcaatcagat agatgcagat attgcttctg caattgaagt agcaacacaa gcactagtat
    19681 ctgctgacgg gaaaaatact gtttacggtg gcacagaaat gcccaaagat gaaccaaaag
    19741 gaaccttaaa aaaaggagac atattattcc taaaagttgg cgatactact agaatgtatt
    19801 tctggaatgg tgctgagtgg gaagaacctg aggttgtgaa cgacccagaa cgatggcgtg
    19861 aagacctcga aaaacaaatc tctgaggcga tcgaaaaagc caaaaaagca caggaagaaa
    19921 tcaaccaacg caccgataaa gagcttgaag aatttagagc cgccctcaaa aacctagcgt
    19981 taccagagga agcgattaaa aaaatcacag aggctataaa agttgatgac atcccgtcta
    20041 ttaaacaaag ctttgatgac ctcaaaaata gagtgagtga gacaagcgaa gaatctcgtt
    20101 taactgccga aattttaggg aacaacggta agacacgcta caacaaaaat ttgctggtcg
    20161 gtgagcctaa tcgtgttaaa aaaattgatg aggattttat cgaggtagaa gctaatgatg
    20221 gtggtttcaa gcgtggcgag acttacacaa tcagctttag tcagacatgt gagccgctca
    20281 aaaaagtggc tatcacgctg atccaagcta ataataaggg agttaaactg gtactgacac
    20341 ctactaaggc aaaaatggag cctgagactt ttactctaat taaggacaca gaggtcatca
    20401 acgtctatcc tttgagctac tcagtcactt taagtggtga ctggtacaaa tctaagcaag
    20461 tagatttaaa tgcgtcggag gtgcgaaata tggctctggg gatgagttat agagatgtgg
    20521 ttgatggtaa taatgctgat ttaattttgg actgggcgga aaacccagat attatttttg
    20581 acggaaacgg aggtatttaa tgtcaaaaga agttgcatca gcaaggatac agcatagagg
    20641 catgaccaaa caagagtggg aatcaagctc cgatatctta atggagcgag aaattggaat
    20701 tgatatgact acgggttacc caaaagttgg tgatggcaaa aataagttca aggacttaaa
    20761 agacttgcgc ggccctatgg gacctcaagg tccttcagga gaaagaggcc taactggccc
    20821 aattggtcct cggggccctg ctggcaagcc tggaacgaca gattataatc aactccaaaa
    20881 taaaccaaat ctagatgcgt ttgcacaaaa aaaagaaact aatagtaaaa tcaccaaatt
    20941 agaatcaagc aaagcagata aaagcgctgt ttactcaaaa gcagagtcaa aaatagagct
    21001 agacaaaaaa ttgagtttga caggcggcat agtgacagga caactacagt ttaaacctaa
    21061 taaaagtggt attaaaccct catcttccgt aggaggagcg attaacattg atatgtctaa
    21121 atcggaaggt gctggtgttg ttgtctattc taacaatgat accagtgatg ggccgttaat
    21181 gagcttgcgg acgggtaaag agaccttcaa taaatcagcg ctttttgtcg attataaggg
    21241 aacaacaaat gccgttaata ttgtgatgcg tcagccaacc acccccaatt tttcatcggc
    21301 gcttaatatt actagcgaca atgaaaatgg tagtgcaatg cagctacgag ggtcagaaaa
    21361 agcgctagga acgctcaaaa tcacacacga aaacccaaac gttgaggcaa aatacgatga
    21421 aaacgctaca gcgttatcta ttgatatcgt taaaaaacag aaaggcggaa aaggtactgc
    21481 tgctcaagga atctacatta actcaacatc aggcacgaca gggaagttgc ttaggattag
    21541 aaaccttagt gatgataagt tctacgtcaa gtctgacggt ggtttttatg ccaaggaaac
    21601 ttcgcagatt gatggcaacc tgaaactcaa ggaccccaca gcgaatgatc atgcggcaac
    21661 caaagcttat gtagataaag caatttctga gttaaaaaaa ctcatactaa aaaaatagat
    21721 taaggaggat aaatgagcag agacccaaca cttattttag acgagtcaaa cctcgttatt
    21781 ggtaaggatg gacgtgtgca ttacacattt accgcagagg acgacaaccc aaaagtcaga
    21841 ctagctagca agtgtctagg cacagcgcat tttaatcagc tcatgattga gcgaggagac
    21901 caagctacta gctatgttgc gccagtagta gttgagggta caggtaatcc gactggacta
    21961 tttaaagacc tcaaagagat tagcctagag ctgacagata ctgctaattc ccagctttgg
    22021 tcaaaaatca agctgactaa ccgtggtatg ttgcaggaat actacgacgg taagatcaag
    22081 accgagatag tcaactccgc cagaggtgtc gctacacgta tcagcgagga tactgataaa
    22141 aagctagcgc tcatcaatga caccattgat ggtatcaggc gtgagtatcg agatgctgat
    22201 aggaagctat ccgcaagcta tcaggcaggc atcgaggggc taaaagccac aatggccaat
    22261 gataaaatcg gtttacaagc tgagattaaa gcctcagcac aagggctatc gcaaaagtat
    22321 gatgatgagt tgcgcaagct atcggctaag atcacaacaa cctcaagcgg cactacagag
    22381 gcctacgaga gtaagcttgc gggcttacgt gctgagttta ctcgctcaaa tcaaggcacg
    22441 aggacagagc tcgagtcaca aattagcggg ctaagagcgg tacagcagtc aacagctagc
    22501 caaatctctc aagagattag agaccgtgaa ggtgctgtca gtcgtgtgca gcagagtttg
    22561 gagagttacc aaaggcggat gcaggacgca gaagaaaact atagtagctt gacccatacg
    22621 gttagagggc tacagagcga cgttggatct ccgactggta aaatccaatc gcgccttact
    22681 caactagcag gacaaattga gcagcgggtt actagagatg gtgtcatgag tattattagt
    22741 ggcgctggag acagcattaa attagctatc caaaaggctg gcggcattaa tgccaaaatg
    22801 tctggtaatg agattatctc agcaattaac ctcaactcct acggagtaac aatcgcaggt
    22861 aaacacatcg ctctcgatgg caatacgact gtcaacggca cctttaccac aaagatagca
    22921 gaggctatca agattagggc tgatcagatt attgcaggca cgattgacgc tgctaggatt
    22981 agagtgatta accttaacgc aagtagtatc gttggtttag acgctaactt tatcaaagct
    23041 aaaattggct atgctatcac tgatttgctc gagggtaagg tcattaaggc tcgtaatgga
    23101 gcgatgctta tcgacttaaa tacagctaag atggacttta atagcgatgc cacaattaat
    23161 tttaatagca aaaacaatgc cttagtacgt aaagatggca cacatactgc ctttgtacat
    23221 tttagtaatg cgacgcccaa aggttataca gggtcagcgt tgtatgcatc gatcgggata
    23281 acctcatctg gtgacggtgt taactcggct tcttccggtc gttttgcagg gctaaggtca
    23341 tttaggtacg ctacgggata taatcatact gctgcagtcg accaaaccga gctatacggt
    23401 gataatgtct tgattgcaga tgactttagc atcaatcgag gatttaaatt tagaccagac
    23461 aagatgcaaa aaatgcttga catgaacgac ttgtatgcgg ctgtagtagc cttaggccgc
    23521 tgttgggggc acttggctaa cgtcggctgg aatactgctc atagcaattt tacaagtgcg
    23581 gtcactaacg agttaaataa tcatatcaac aaaatttaat aggagaaaca atggatttaa
    23641 cgcttaaaaa caaagattta aacacactat atagtgtact agacaaaatc aaagtcacga
    23701 acatgcgagc aaaccgcgga cgtgctaagc tactcgcaaa agtagtcgat aaattcaaag
    23761 agtacgccaa ggatgagggt gaccttattg atctgtatgc tcaaaaagac aaagatggca
    23821 agtttgtcat tgatgagcac aaaaacatca agctagcaga ccccgctaaa ctcgacgagt
    23881 tcaacggcct actcaacgag ctagctgatg aagaaattgt gattaaaggg ggtgagtact
    23941 ccaagcgatt tattgacttt ttaaactttt tagaagagtg tgaagatgaa tttacatcat
    24001 ctgaaatcat tcttatcgac aacattttgg aacaatttga agaaagtaaa aaaggagaaa
    24061 aaccatgaga aattggaaag tgacaggaaa atacccacaa tttgacagca caggagcagt
    24121 cgcaagcaca catattatta tcactgctga ggatggctca gtcatctctc aaccaatcaa
    24181 gcagggctta acttcaacta atgacacaga gattatcaaa gctactttgg aagaatttaa
    24241 aaaatctgaa tacgtcgaaa tcgctatggg cgaagccgtg caaaaagtag acgaccttga
    24301 aaaaatctca caggaaaccg ctaagaccgc taaaacagcc caaacagccg caggattagc
    24361 taaggtgtcc gcagagcgta cacagcggat gattaacttg caaaccatcc acgtattgac
    24421 aagtggtggg aaagttgaac ccgatatcta caaaggtatg ttagagctta ttgaacctgc
    24481 taaacaaggc gagtatcagg cttatgacgt gtttactgtt gtagatgagt cgcacgaaga
    24541 tcaagcggga gaaggtaatc ttgtctttgt acacgttaac gagccgttta cttatgacaa
    24601 acagacgctt aaagagctag aggaagagga taaagtcaca gtcattaagt atgcggactt
    24661 agttaagcag gattagcgag gtaagctatg gcaacagagt tgatatttgg tcttggtggc
    24721 tttattttag ctatcgtcac gacttacaat atttttaatg caaaatccat caagcatgcg
    24781 acagatatta ctttgttgca gtctgaagta gagcatttaa aaattgttac acgccaaaat
    24841 gctcggcgtc ttgaggagca tgatgagcaa aacaaaacgc tcatcacaat gacagagcaa
    24901 attaaaaacc tcaatcgtga ggtaagagaa cttaaagata ttatgagagg tgaagcatga
    24961 tcaatttaaa attacgacta caaaacaaag taaccttgat ggctatttta ggagctatct
    25021 ttttactggc acagcaatta ggtattaaac taccatcaaa catcgcggat attgcaaaca
    25081 cagctgtaac gcttttggta ttgctcggtg ttgtcacaga tccaaccacg aaaggcctgt
    25141 cagacagtga gcaagctttg acttaccacg aaccaaaaca ataggagggg acatgcgggc
    25201 aatcacacga ttagcattag ttatagcaat agcaatactg tatgtgccat tatctgttgt
    25261 tgctttgatt ttaagcccat ttttagataa ggagggataa atggctacat atcaggaata
    25321 taaaagtcgt tcaaatggca atgcttacga tattgatgga tcgcttggtg cgcaatgttg
    25381 ggatggctac gcagactact gtaagtatct aggactgcca tacgcaaact gtacaaatac
    25441 aggatatgca agggatatat gggaacaacg tcacaaaaat ggtattttaa actactttga
    25501 cgaagtagag actatgcaag ctggagatgt cgcaattttt atggtagttg caggtgttac
    25561 accgtatagc catgtggcta tttttgatag tgatgcaggt agtggatacg gatggttttt
    25621 aggtcaaaac cagggtggag caaacggagc atataattta gtaaaaatac catattcaac
    25681 gacttatcct actgcattta gaccaaaagt ttttaaaaat gcagttactg ttataggtaa
    25741 tataggacta aataaaggcg attattttat tgatgtatca gcttatcaac aagcagactt
    25801 aaccgctact tgtcagcaag ctggcactac taaaacgatt atcaaagtat ccgagtcact
    25861 cgcttggctg tctgataggc atcagcaaca agctaatact agtgacccta ttggttatta
    25921 tcactttgga cgatttggag gagatagcaa cttagcgcaa cgagaagcag atttatttct
    25981 gtccaattta ccaaccaaaa aagtctctta cttagtcatt gattatgaag actctgcaag
    26041 tgccgacaaa gaagctaaca ctaatgcagt tattgcgttt atggataaaa ttgcaaacgc
    26101 tggatataag cctgtttatt acagctataa accatttacg cttaataata ttgattatca
    26161 gcaaattatc gctaagtacc caaacagcat ttggatagct ggttatccag actacgaagt
    26221 acgaacagag ccactttggg agttcttccc ttcaatggat ggtgtgcgct ggtggcagtt
    26281 cacaagtgta ggagtagcag gtggtttaga taaaaatatt gtattattag cagatgatag
    26341 tagcaaagtg gatataccta agattgacaa accacaaagc cagcttactt ttaatcaaaa
    26401 gctagatact aacactaaat tagacaactc gaatgtacct tactacgaag caacccttag
    26461 cacagactat tatgtagagt ctaagccaaa cgcaagtagc gctgataaag aatttatcaa
    26521 ggcaggaact cgtgtaagag tctatgaaaa agtgaatgga tggtcacgta ttaacgcttc
    26581 tcagtctgac cagtgggtcg aagataagta tttatctaat gcaacacaag tataaaatag
    26641 gaggtaaagc tcctttagat aagacaaatg ccctcgcttt tgcgggggct gtttttgtta
    26701 taaagatttt aattgttatt taagcatttt cgttgatttt tttctttttt gtgctaaaat
    26761 attttgtgat ttcttattat taaagaagaa tagggtacac ttataagtga gaaaaattgt
    26821 aaatgttaat tttaaaaagt ttttaacttc atcttttcta ttgtgggtat ttata
//
LOCUS       DARYLD010000029        26672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYLD010000029 DARYLD010000000
VERSION     DARYLD010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            133..348
                     /locus_tag="TU651_001083"
     CDS             133..348
                     /locus_tag="TU651_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0897092.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            348..1211
                     /locus_tag="TU651_001084"
     CDS             348..1211
                     /locus_tag="TU651_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897093.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1284..1778
                     /locus_tag="TU651_001085"
     CDS             1284..1778
                     /locus_tag="TU651_001085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0897094.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            1782..2192
                     /locus_tag="TU651_001086"
     CDS             1782..2192
                     /locus_tag="TU651_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0897095.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            2152..4629
                     /locus_tag="TU651_001087"
     CDS             2152..4629
                     /locus_tag="TU651_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL0897096.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVEVEFSYINSIGENEEINKLIDIKENIDDFNEIRNEY
                     RQMLLNQSSKGNNGLSKSMYITFTIEAEDLKQAKSRLERMEMDVLNNFKQMGVKAYVL
                     DGEERLKTIHDILNPNDKLVFSFEDLKYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAE
                     VNFLQLLASDIKDEMLSEFLALEENMIVTFHIRAIDQMEAIKHVKRKITDLDKMKLEE
                     NKKAIRAGYDMDILPSDLVTYGAEAKNLLSELQNHDEKMFLITILFMNTSKSKGKLDN
                     TVFTLKSIANRHNCSLKNLNYRQEQGLVASLPLGINEVEIERGLTTSAAAIFIPFTTE
                     ELFIKGESLYYGLNALSRNIIMADRKKLKNPNGLILGTPGSGKSFAAKREITNAFLIT
                     DDDIIIADPEAEYSPLVEALKGQVIRISPISKDYVNPLDINIDYADEDNPLSLKSDFI
                     LSLFELVVGEKKLSAEEISVIDRCLPILYKTYFENPVPENMPILEDLYNLLQKQEEIV
                     GKKLAVEMEIYVKGSLNVFNHRTNVDTNNRVVCYDIKELGKQLKKIGMLVVQDQVWNR
                     VTINRASKKATRYYVDEFHLLLKEPQTANYSIEIWKRFRKWGGMPTGLTQNIKDLLAS
                     PEIENIFDNTDFILMLNQAGTDRDILAKKLNISKHQLSYVTNSGEGEGLIFYGNTIVP
                     FIDQFPKNTKLYSLITTKPEEVKKAGE"
     gene            4631..5656
                     /locus_tag="TU651_001088"
     CDS             4631..5656
                     /locus_tag="TU651_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL0897097.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            5622..7910
                     /locus_tag="TU651_001089"
     CDS             5622..7910
                     /locus_tag="TU651_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0897098.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            7923..8210
                     /locus_tag="TU651_001090"
     CDS             7923..8210
                     /locus_tag="TU651_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0897099.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            8215..9651
                     /locus_tag="TU651_001091"
     CDS             8215..9651
                     /locus_tag="TU651_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0897100.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            9904..10497
                     /locus_tag="TU651_001092"
     CDS             9904..10497
                     /locus_tag="TU651_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL0897101.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     IQSYSSYKERDIHSLYDIAMKMGIENKVREVMEVAYE"
     gene            10490..11332
                     /locus_tag="TU651_001093"
     CDS             10490..11332
                     /locus_tag="TU651_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL0897102.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIYARGFLNSRSKDYYDLYIIYKLKDKDVNVEILREACRKTF
                     SYRKTEFDIGKIIDLLEKLKINEAFLKRWQAYSRKNLYAKDITFEEVLDNGIKMVEKI
                     KNEN"
     gene            11504..13216
                     /locus_tag="TU651_001094"
     CDS             11504..13216
                     /locus_tag="TU651_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL0897103.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            13220..13771
                     /locus_tag="TU651_001095"
     CDS             13220..13771
                     /locus_tag="TU651_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL0897104.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            13813..14559
                     /locus_tag="TU651_001096"
     CDS             13813..14559
                     /locus_tag="TU651_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0897105.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            16380..16871
                     /locus_tag="TU651_001097"
     CDS             16380..16871
                     /locus_tag="TU651_001097"
                     /inference="COORDINATES: protein motif:HMM:NF025561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HEL0897106.1"
                     /translation="MKKKEMKEVWKMKETVVLAKKEYILENEIYTPIVKESPFERQGG
                     TYRLEKMEDGAEVLVPNMKMPEKINASKLNRFGKERLKYLKEEKQEEYQIMLMEETLM
                     DHLIDIQEQVEDFLNIEEPRMKEAWKMTTEMQDQDFLKYTGLKKNLDMTLTKMAMEQI
                     IWV"
     gene            19085..26503
                     /locus_tag="TU651_001098"
     CDS             19085..26503
                     /locus_tag="TU651_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL0897107.1"
                     /translation="MKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNE
                     QFPDYYNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVL
                     STLIFKDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLD
                     MKNKELRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEK
                     DKAKEERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEII
                     PFRNERELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNF
                     NPVGMSRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQM
                     SLTDIFEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWL
                     NPVSKNNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIAN
                     QFIVKVDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETID
                     KKLKSYHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYL
                     GGIPPINYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWG
                     GLSDVFDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNM
                     GFESGNILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFE
                     ETTFSNNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISS
                     SGTMDKKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDE
                     EWVKLGTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAI
                     KNIKGSYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEE
                     KVRAYLGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLF
                     REDANYSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGK
                     VNFEYMEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADE
                     YLSGNIRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQK
                     LLEVMPKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYR
                     VEGKSIDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKE
                     TMLARSKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPE
                     IELRPHQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHI
                     VEQFGREFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPIS
                     KQRQEYELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDV
                     VTFEELGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGN
                     KGIVFATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEG
                     NGYRSKTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQIL
                     ETFSERADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNI
                     FSIWDKYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKE
                     KDKIFDKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQ
                     GNENDDVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAE
                     IKALATGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDKVVKVYPKEIKSLKEKIE
                     NLKKDIEKVEPYREEKLEKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYT
                     DKKQAGEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENH
                     YGEFGTDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLK
                     EKTLRLAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFP
                     DLTDIGLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELI
                     QIKTNIGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFR
                     DSKVQSFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
BASE COUNT        10738 a         3296 c         5549 g         7089 t
ORIGIN      
        1 aatataataa aatcaataag gataagaagt ccaactttaa gaaaattgaa tagcaaaagt
       61 ttaacgattg gaagagaaga tttccagtcg tttttttatg aaaataagta aaataatgag
      121 gaggaataaa ttatggattt ttttgtacag gcagtaaatg tgcttaaaat tttggttatg
      181 gcaatcggtg caggacttgg tgcatgggga gttatcaact tacttgaagg atacggatca
      241 gataatcccg gtgccaagtc gcaaggaatc aagcaattga tgagcggtgg aggaattgtt
      301 ttaatagggc tgaaactaat tccgctactt gctaatgtct tgagataatg tttgatttat
      361 ttggaaagat agaagagttt ttcaaggata ttatgattga tattattaaa gataatcttt
      421 ctgcaatgct tgtggatatt aatgataaag taggaaccgt tgcaggagaa gtgggaaaga
      481 ctccgagttc ttggaactcg gaggtcttca ccttcattaa atcaatcaat accaatgttg
      541 ttttacccat agcagcgata attctaaccg caatactttg catagaactg attcaggtgg
      601 taatgagaaa aaattctatg cacgatacgg atacctttga attttttaag tacattatta
      661 aaatgtggat agctgtatgg cttgtgtctc atgcgtttga tttttcaatg gcagtctttg
      721 atgtggcaca gtccatgata ggaaaggcag caggtgttgt ggggacaagt gcgaatatca
      781 caccgggaaa ttttgatgct atggtagaag cccttaaaac aaaggaactt ggaacactca
      841 ttgggattgc actggagacg ggattagtta aattttcttt aacgattcta tcaatcttaa
      901 tcactgtaat cctatatgga agaatgattg agatatatat ctattgctct gttgcggcaa
      961 ttccattttc tacgatggga aataaagaat ggtcaaatat cggaacaaac tatataaaaa
     1021 gtctatttgc ccttggactt cagggacttt tcatcctaat attttttgga atttacgcag
     1081 tcttagtcaa aaccgtaaac tttacggata tccacacaag tattttacag gtattggcat
     1141 atggattgat tcttggagta atgatgatga aatccggaag tatagcaaag gcgattttaa
     1201 acagtcacta aaggacttta gttcaaaatg agcaaaagtt gatgaaataa tcagaacaaa
     1261 aaatataatt attggaggta agaatgaata aaataaataa aaaaacaagg attttgatag
     1321 gagcaggctc agccctttct atcgggacaa ttattacagt gctattaaaa aagaaaacga
     1381 aaaaattatc cgatcttgaa gaagatgatt ttgactttga ttttgatgaa atagaagaag
     1441 attcttgtgt caacgataaa tttgctacag aaaatgataa agatgataca gtaaaaggag
     1501 aaatagattt tttagtagat gaatcaaaga cggagaacga aaagcaagaa gagtttagag
     1561 atttatcggt aaaggtaatg gatcttcttc taaaagaagt aatttcaatg agtgaaacct
     1621 taaatttggt aaaaagagat attgatagaa taggtgaagt aaaagcattg gttgaagaac
     1681 tggaaaactg taaagaagaa attatctcac tttgggagca catggaaaag ttatccgatt
     1741 taagagaaga aattaccggc aaaaagaata gaggttaggc tatggcttat gtaaagatac
     1801 caaaagacct tacaaaagta aaaaccaagg tagccctgaa tatgacaaaa aggcagctta
     1861 taggttttag catagcaggg cttatcggtt ttcctgtata tatgctgtgt aaaaattttc
     1921 ttagtacaga tatttccatg attataatga gtatagtagt tctacctgtt ctttttgtaa
     1981 cgctttatga aaaggacaat ttaccttttg aaaaacattt agcatatatc ctcaggtttc
     2041 ataaaagtaa aaagatcagg ctatataaag cgaggagcat ttatcataca gagagagcaa
     2101 aaaagcaaga tataggaaat aaaaataagg caagcggaag gaggaaaaaa gttgaacaaa
     2161 gacaaaagaa aaaaacagga acaacgaatt aaaaaggatg agttggagct taggaaaaat
     2221 agaaaggagc tatccgaact taaaaaaaca ggaaagaaaa aaacaaagtc taaaacaaaa
     2281 gggaaatcat cgaagaagaa tgggtggttt ccttttttta tgaaagagga gaaaaaagaa
     2341 accgtacagg ataccattcc atataagcga atgttaaaag acgggatttg tcaaattgaa
     2401 aagaataagt ttaataaaac cattcgattt ttggacatta actatcgctt aatggaagaa
     2461 atagaccaag agggaatatt ttcggaattt tcttcttttc taaatttctt tgactcatct
     2521 gtggaagtgg agttcagcta tatcaacagt atcggagaaa atgaagaaat caataaactg
     2581 attgatatta aggaaaatat agatgatttt aatgaaatta gaaacgaata tagacaaatg
     2641 ctcttaaatc aaagcagcaa agggaataat ggattatcaa agagtatgta cattaccttt
     2701 accatagagg cggaggactt aaagcaggca aaaagtagat tagagcgaat ggaaatggat
     2761 gtattaaaca actttaagca gatgggagtg aaagcctatg tgttagatgg agaggaaaga
     2821 cttaaaacaa ttcatgacat tttaaatcca aatgataaac ttgttttttc ctttgaggat
     2881 ttgaaataca gcggactgac gactaaggaa tacattgtac ctccgtcttt taacttttcc
     2941 aagccgacgt attttaagac aggagaagtc tttgcggaag taaatttttt acagctttta
     3001 gcatcagata ttaaagatga gatgttatca gagtttttgg cattggaaga aaatatgatt
     3061 gttacttttc atatcagagc aatcgaccag atggaagcta ttaaacatgt aaaaagaaaa
     3121 ataacggatt tggataagat gaagcttgag gaaaacaaaa aagctattcg tgcgggatat
     3181 gatatggata tcttgccaag cgaccttgta acttatggtg cagaggcaaa gaacttgcta
     3241 tcagaactac aaaaccatga tgaaaagatg tttctcataa caattttatt tatgaacacg
     3301 agtaaaagta aggggaaact cgataatacg gtatttacct taaagtccat tgcaaataga
     3361 cataattgta gtttgaaaaa cctaaattat agacaagaac aagggcttgt tgcaagcctt
     3421 ccacttggga taaatgaagt ggagatagaa cgaggactta ccacaagtgc agcagctatt
     3481 tttataccat ttacaacaga agaactcttt atcaagggag aaagcctata ttacggacta
     3541 aatgcactaa gcagaaatat tattatggcg gacaggaaga aattaaagaa cccaaatggt
     3601 ctaatcttag ggacaccggg ttctggaaag tcctttgcag ccaaaagaga gattactaat
     3661 gcgtttttga ttacagatga tgatattatc attgcagatc cggaagcgga atattctccg
     3721 cttgtagagg cactaaaagg acaagttatc agaatttctc cgatttcaaa agactatgtc
     3781 aatccactgg acatcaatat tgactatgcg gatgaagata atcctttgtc tttaaaatcc
     3841 gactttattt tgtccctatt tgaattggtg gttggagaaa agaaattaag tgcagaagaa
     3901 atttctgtta tagaccgttg tttaccaatt ttatataaaa cctactttga aaatcctgtg
     3961 ccggaaaata tgccaatttt agaggattta tataatcttc ttcaaaaaca ggaagaaata
     4021 gtaggaaaaa agcttgcagt agaaatggag atctatgtaa aaggaagtct taatgtattt
     4081 aatcatagaa cgaatgtaga tacaaataac agagtggttt gctatgacat caaagaactg
     4141 ggaaaacagc ttaaaaagat aggaatgtta gttgtgcagg atcaagtttg gaatagagtt
     4201 acaattaaca gagcaagtaa aaaagcaacc agatattatg ttgatgaatt tcatcttttg
     4261 ttgaaagaac cgcaaacagc caattattcg attgaaatct ggaagcgttt cagaaaatgg
     4321 ggtggtatgc caacaggact tactcaaaat atcaaagacc ttcttgcaag cccggagatt
     4381 gaaaatattt ttgataatac ggattttatt ttaatgctta atcaagcagg aacagatagg
     4441 gatattttag ccaagaagct caatatctcc aagcatcagc tttcttatgt aacaaattcg
     4501 ggggaaggag aaggacttat cttttatgga aatacgattg ttccttttat cgatcagttt
     4561 ccaaaaaata caaaactata ttcactaatc acaaccaaac ctgaagaagt aaaaaaggca
     4621 ggtgaatagg atgagtgtga gcagaagtaa agaggaattc atcaaagaaa atacaaataa
     4681 aattatttgt tcggatgcac ttgaaacttt aagaaaaatt ccagacgaaa gtataagctg
     4741 ctgcattaca tctcccccat actacaggct cagaaactat cataaagaag gtcagatagg
     4801 aagagaatct acagtagaag aatacttgga tagattgtta caggtatttc gtgaagtaag
     4861 aagagcttta aaaaaagaag gtacttgctt tatcgtaatt ggagattctt atgctgattc
     4921 aggaggtgga aagggacaat acattgatcc taaatatcca aaggcaagaa atggaagtaa
     4981 cgctttagct acagaaaata tctcagggta caagtcaaaa gatttaatgg gaataccttg
     5041 gagattagcg ttacttctaa gagaggatgg ttggtatctg cgttctgata ttatctggca
     5101 taaggaaaat gctatgccgg aggcgtgtag agatagacct actcgttcct atgaacatat
     5161 ttttttactt acgaaatcac caaaatacta ttatgactat gatgctatgg tagagccgat
     5221 gaaagaagtc agtaaaaaaa gatatgtaag aggaagaaaa tcggataata aatatctgaa
     5281 agaaaattcc ggagcaaagt tgcaaaaaat caatgaagca agaaaatatg gagaatataa
     5341 gggcgataat gtcccgcagt ttcgtaataa aagagatatt tggactatca ataccacatc
     5401 ttttagaggc aatcattatg caacatttcc accgaaactt gttgagattt gtatgattgc
     5461 aggttgtcct aaaaatgaaa ttgtacttga tcctttcatt ggaagtggaa cggtcggatt
     5521 tgtggcactt cgtcataaca gaaagtacat tggaattgaa ttaaatgagg agtatgtaaa
     5581 tcttgcaaag aatagaatca gtgaggaggt gaaaaaattt aatgaagaac aaaaacaaga
     5641 ggtacaaaaa gaatagagaa aaactcttaa atcaagaaat acagtcttta caatctcaaa
     5701 ctcaagataa ttatgaaaca ggatcctcaa aaaatcagaa tgaaaccttg ctgaaagacg
     5761 aaacttacga taagaaacaa tttttatctg aaaagaagtt atccaatcat ttggataata
     5821 gacatataaa taattattcg gatagaacta tatcttctta ttgcttgtcg gatacgggaa
     5881 atataaatca aaataggtct tcctttcaag ctgaaaaaca taaaaaaaag atgcaaaagc
     5941 agataaataa atttcaaaag ggagaaaagg aagtctacga tcctttatca aaagatatgg
     6001 ataatgatgg tgtaatagac aggtatgatg tggattttag ggatagcaaa gtatcatatc
     6061 gaactcttac agatgatgaa aagtatgata ataaccaaaa tgataaagga aaaaattata
     6121 atgactatgt aaaaaatcca aaatctaaga ataagaggta taaaaattat gtaaaagaca
     6181 cattttctaa ggaaagaatg aaatcagaaa accagaagaa atatgtgagg agcaactttg
     6241 atgatgaaga gttcacaaga aataaggata cgaaaaataa tttatttcag gacgtaaata
     6301 ataaaagaaa aactaccgat aaaaattcat cacgaaaaag aaaaggaaaa tttgaaaata
     6361 aggaaaagaa aatatccaag ttacagcaga aaaagcaaag acaagagcaa aaactgaaaa
     6421 ataagggaat tgacgggaaa agtcaaagtg ctaaaagtgc agtaatagca acgggtatgg
     6481 caaagaggta tttggaaagt ggaaaagagg acaatgccgg agtaggtact gcttataagg
     6541 ttacagatca ggtcgaaaat atttcaagga aaatatatta tcatggaaaa aagaaaaatt
     6601 taaaaaggca aaaaaagata acaaaattag gtaaaagcat tgataaacag gagaagaaac
     6661 tcttttttca aaagaatatg gaagagatga aaaaaagcgt ggattaccaa aatacctcaa
     6721 ggctcagaca attctttaag agaaggcaat ataaaaatca gattcaaaag aagtataaag
     6781 atagtgtgaa aaacagaata aaaaaatcct ttatagaggg cagtaaaaga tttggcgaat
     6841 ttgtaaaggg cagagggaaa aagataatat ttctatcact tttagcggta ggaatatttt
     6901 ttatgttatt tcaggctggg agcatgatga tgaatatggg aacgggaatg gtaagtaata
     6961 ctgtttcaac cacctactta tcatcagaag acaccttaaa agaaatcaat cagaggtttt
     7021 catctttgga acaggctttg caagaagaaa tggacagtgt ggaggaaaat catccgggct
     7081 atgatgaata tattatcaaa ggaaaagaga aaattggtca taatgttcat gaactcttgt
     7141 catatatcac agcccgttat ggaattgtaa agaatatttc tgaagtagaa agtgaactaa
     7201 aacatctgtt tcaaaaaatg tatacgctga cttataaaga agagattgaa atcagatata
     7261 gaactgttac atccagctat acggatgctg atggcaatga acatactgaa agtcatgaag
     7321 agccgtatga gtataggaaa ctcattgtaa ccttagaaaa aagagagatg gacggaatta
     7381 ttagagaagc atttaagcgt tatcctaata atttggcaca ctatgaaact ttatttttga
     7441 cacaaggaaa tatgggagaa gtatttggaa atattgacct tataaattca aatggtggaa
     7501 ttggtggtgg taaagagtat gaagcatcaa gtgaagtgca aaagaaaata gtgaatgccg
     7561 cttatattac accatctcca ggagcaggtt ggtgtgccat gtgggtatca caggtctatc
     7621 aaaatgcagg acttggattt attggaggaa atgcttgtga tatgtatcga aattatactt
     7681 ttacttctga taggtcaaag ttaaaggttg gaatgcttgt tgcagttgaa agtagcagta
     7741 gtggtagcag tttaggtgtt acctatggtc atgtaggtat ttatatcgga gatggaaaag
     7801 taatggataa tatcggacac ataagagtaa ctaccctaga tgattggatt gcaacatttt
     7861 gcaaacatca ccctgtaggt tttggatttc caccatcagt acaaaaataa ggagggaata
     7921 ttttgaataa aaaatataga aaaaatatag aaaagcaaaa agatattcag aaaaaaatag
     7981 aagaactcca gttaaaacag gagatgttaa aagaagaaca ggaagagatg gaaaatattg
     8041 aggttttaaa ggaataccga agtattgaca tttctattga cgatttttta gaaatgatga
     8101 gacgttataa aaaagaggaa aaacaagaaa aaatgaagtt acaggaaatg agaaatacag
     8161 aaaatcataa taatatggag gaaaatcatg aaaatcaaat ggaagaataa aaaaatggcg
     8221 ataacattgt ccggagtaat ctttttgata cttgctttac ttggaacaat gcttttcaat
     8281 caccagattg tttttgcaca aggtagttta atcccgacac tgattagtcc cacagaagtt
     8341 ttagctcaaa ctaaagtgga ggttaagata aaatatatat ttaaggatga gagtgtatat
     8401 aaggaagaaa taattgaagt agaaaccggg caagttcttg acagtgggga cctaccaatg
     8461 ttagaggata atatgaaatt tattgacgaa tttttgttct ataaagtaaa gggagacggt
     8521 acagatgaga ttatccgtaa agtagaaaaa attacagtta aggataaaga aattcagaca
     8581 gaagaggaaa agccaaaaca ggacgaaagc actgagacgg aagataaaaa aacagaagat
     8641 aagggaacac agacagagct ttctaaagat gatatttcca aaatggaaaa agaggcaaaa
     8701 gagcttcagg ataaacttga taaattaaat ggtgaaatca gggataaaga caaactaagc
     8761 gataaacaga aagaaaaaat caaagacctt gaagctgaga ttgaaagtct gaaagaaaaa
     8821 atgaagaaag ataagggaaa taaagactta tcagaagata tgaaaaagga aatagataag
     8881 ctgacggaaa aggtgaaaga gcttgagaaa aagccaactg aaacaaacaa agctcctgta
     8941 acatcacagt ctgttacacc gattagtcct atttcaggga ttaagacaag ctcaggtatt
     9001 tcttctcaaa caccacagag ttccggtaaa ggttcatctg atgcagtaag ctccggcaat
     9061 actacaaaag atacaggtaa aactgaatca aaggagaaag aaaaggaagt tcgctatccc
     9121 aataagctga caccgaaagc tcctgctaat aacagtagtc aggattcatc aatggacggt
     9181 gcaagtagca atgtaaatac caataagggt gtggcttcag ctccgtcaaa ggcaagagga
     9241 actgttacag aaaataaaga taatgcgaat aatgattatc caattcatca tggggatagc
     9301 agcgataaca aagaagcaga taagtattca gcagatgcaa gacaatttat tactttccag
     9361 acaaaatccg gaaagacatt tcatttaatc atcaatcacg atgagcaaag tgaaaatgta
     9421 atgcttttga ctgaagtatc tgaagatgat cttctgaata tggtagagaa gaaggaaaac
     9481 ccgcaagaag aaatcaaaaa aatggaagaa acggtaccgg aaagcgaagt aaaaaaagaa
     9541 gagccgaaaa aggaagaagg taaaggtagc ggctcatata tttttttagg aatcatcgtt
     9601 cttgcagtag ttggagcagg atattacttt aaaatctaca agaaaaagta ggaagatgat
     9661 gattatgatg aagatgagga agaatatgat gaatttgaag atgagtatga aaaagaggac
     9721 gatacagaag atttggaaga aacagtagaa gaacagcata acatagatga tatggcaatc
     9781 gactcttatg atgaagaaga tgaggaataa agttataaaa agagaaatgt aaaccctgat
     9841 gttgcgttta cacttaaaaa atggtataat gcaagtgtaa acgcaacaaa gggggtggat
     9901 gggatgaatt atgaaaataa aattgaaaaa tatttgaagc aatcaggtgg aattattaca
     9961 acagcatact gtaaggaaaa taatataccg acgatatatc tcagtcgact attgaaagat
    10021 gggagattgt caaaagtaag aaaaggaatt tatataacga aagatgggga ttacgatgag
    10081 tattatttct ttcaacatca gtataaaaag gcgatatttt cttatgaaac agcactttac
    10141 ctgcttggac aaacagataa aattccttgg agtatcgatg taaccgttta taacggatat
    10201 aaatttaatg aaaaaccgaa cggtttcaat gttcattatg taaaaaaatc aatttatgac
    10261 ttaggggtaa cccaaaaacc tacaatgttt ggaaataaag ttaaggtata ttcatatgag
    10321 aggacactct gtgattttat tgctcataaa gaagaaatgg atatagaggt ttatgtaaaa
    10381 cttattcaat catattcctc ttataaagaa agagatatcc attccctcta tgacattgca
    10441 atgaaaatgg gaattgaaaa taaagtaaga gaggttatgg aggtggctta tgaataaagc
    10501 taaattaacg gctctttgcc ataaagttag taaagaagtc ggtctttcgt ttaatgctgt
    10561 tatgttatat tattttttag aaagtatttt aaaaaaatta gcaggaagca aatatagtga
    10621 acgatttatt tttaagggcg gctttttgtt atcaagtgta gttggaattg attcaagaag
    10681 tactgtagat atagactttc ttttgagaaa tatgcaacta tcagaagaaa atattgttca
    10741 aatgctgaac gaaactttaa aaccggaaga attcgacgat attttttatg aattgcaaaa
    10801 cattgtgcca atcaaagaag aagatcaata tggaggattt cgtgcaaata tcttatgtaa
    10861 aatggaaaat ataagacaga ttgtaccact tgacattgca acaggagatg ttattacacc
    10921 tcatccgata gattataagt atgtgagttc ttttggagaa gaagaaataa taatcaaggc
    10981 ttatccgata gaaactatgc ttgcagaaaa aatacaaact atttatgcaa gaggattttt
    11041 aaatagtaga agtaaggatt attacgatct ttatattatt tataaattaa aggataaaga
    11101 tgtaaatgta gagatattaa gagaggcttg cagaaaaact tttagttata gaaaaacaga
    11161 atttgacata ggtaaaatca tagacttact ggaaaaattg aaaataaatg aagccttttt
    11221 gaaaagatgg caagcttatt caagaaaaaa tctgtatgcg aaagatataa cttttgaaga
    11281 agtattggac aacggaataa aaatggtgga aaaaataaag aatgaaaatt agcatataac
    11341 ggttttacaa tgaaaagaag gcgtcaaaca tttttttgta agttagttcc caaacaggaa
    11401 aatggattaa aaaatagaaa atgaaatata taaaacttta aaagacaatt ggagaaatgc
    11461 aaactctgat tgtctttttt catgtagaaa aaaggaggaa tttatgcaaa cactggtgat
    11521 aagtgaaaaa ccgagtgttg caataagcat atcaaaggtg cttggagcaa caaaaaagaa
    11581 agacggatat aatgagggaa atggatatag ggtaagttgg tgtgttggtc atttaattca
    11641 gatggcaaat ccggatgctt atgatgaaaa gtatgccaag tgggatatgg ctgatttacc
    11701 gattattccc aaggactata agtatgaagt agcaaaggca accaagaagc aattcaacat
    11761 ccttaaaaag ctgatgaatg ataaagaaat tgatacggtt ataaatgctt gcgatgcagg
    11821 tcgtgaggga gagagcattt ttagacttgt ttataatcaa gtgaattgta aaaagaaaat
    11881 gaaacgcctt tggatttcat ctatggaaga tagtgcgatt aaagagggtt ttgatcatct
    11941 aaaagacgga aagaaatatg acaatctctt tgaatcggca caggcaagag ccattgcaga
    12001 ttggttagtc ggaatgaata ttagtagact ttattcctgc ttatataatc aaaattactc
    12061 tgtcggtagg gtgcagacgc caactcttgc catgattgta aaacgagatg acgagatagc
    12121 aaactttaaa aaagaaaaat attatactgt agagctatct atggacggtt ttatactttc
    12181 cacagacaga attgatgata aggtagcagc agagcagcta atcaatttag ttggtgataa
    12241 gattgaaatt accgatgtca ttcaaaatga aaagattaca aagccggatt taccttttga
    12301 cctgacaaca cttcaaagag agtgcaataa atattttgga tactcagcta agcagactct
    12361 tgattatgct caaagtctgt atgagaagaa acttattacc tatccaagaa cagacagtag
    12421 atgccttact gaagatatga ttacaagtat gataaataac atattgggac aaaatgactt
    12481 tgatacaggg cgtattaagg tcatttttaa ttcaagcaag gtaacggatc atcatgctat
    12541 tataccgaca gtaagttcaa tgagtgaaga tttattgagt attccggaga gtgaagcaaa
    12601 agtgtatgga cttattttta ataagttaca cgcaagtgtg ggctatcctt taatcgagaa
    12661 tacaacaaag attgtagtga cttttgacgg ctttaaattt acaagttccg gaaaagtaat
    12721 taaggatgag gggtttacta agtatttaaa ggaatataag acgaaaaaga atgaagatat
    12781 agaacttcca aatgtaaata taggtgatag tcttaaaatc aaggataaag aaatcaaaga
    12841 aaaatatacg caacctccaa aacattttac ggaaaacacc ttattaaaaa gcatggaaac
    12901 agcaggaaat gacgctttaa aaaaaggtat tgaggttgaa agaaagggta ttggcacacc
    12961 cgcaactcgt gcagggatta tagaaaatct aatttacaaa ggctttattc aaagagataa
    13021 gaaaaatctt gtagctacac ataaaggaat tagtcttata acaattgttg cagacaactt
    13081 taaatctgct gaaacaactg caaagtggga aatggagttg tctgatattt ctcaagggaa
    13141 atcttcaaag gaagaatttt taagaagagt agaagctgag ataagaaatg aattatcccg
    13201 ttataaaaag gattagtcta tgtttgatac tctaataaaa tttagtaaag acagagaaaa
    13261 attggatttt tatgccacag ataaaagggc aattcatgaa cttttaaaaa gagagcagtt
    13321 tctatctcct atttatgagc cggcttgtgg aatggggcat atcggaaaag ttctggaaga
    13381 atacggttat aaggtaaaag ctacagatat ttgttatagg ggatatggag aagaaagaga
    13441 agttgatttt tttacagtaa cagaaaatat attggatata gtaaccaatc caccatattt
    13501 ttgtgcaagt gagtttttaa ggcacgctct tgaaatatca ggacctaaag taaagatagc
    13561 aatgctattt cggttggctt ttttggaagg tcaatcaaga tatgaattat ttaggaaata
    13621 tcctccaaag agagtatatg tattttccaa aaggcttaat tgtgcaaaaa acggagaatt
    13681 tgagaaatac aaaagcagtg ctattgcctt tgcctggttt atatgggagg tgggatacaa
    13741 aggtattacg gagttaaggt ggattagata aaaggatgga ataaaacaac tgaaaaaacg
    13801 aaggaggata gtatggataa gaatgaagta ttacaatcac aggaaaatca gacaaaggaa
    13861 gttatgcagg agattaaaga ggaatatacc aaaacagctg actttttaga agaacatata
    13921 aatcagcagc ttgtgattgc taaggaaatg aaagaagaga tgcaaaataa ggactttgat
    13981 gtaaatatca aagaattgaa agcactcaaa gaagaaatca ccggattaaa agctgaaatt
    14041 aaacgattaa acgaaatgga aaatataact tttggttcat tgattataag agatatcaaa
    14101 tctgtaggaa atacccttat caatttacag gaaaaagcgg taggaagtat taaacatctg
    14161 tatgataata tgaaacatca gctttcctat aaccttacca aagcacagga aaaatttgta
    14221 cagatgaaaa taggaattgt aaaaggattg gtaaattcca tgcaggattt tatcaaggat
    14281 caacaaaaga aactggatag ttgcttagca aaacttgata atctatctaa agaaattcaa
    14341 aaagatgaag aaaaactgga aaaaggcaat ctgaataaag agaaaaccct gataaaaaaa
    14401 agggaacaaa gcatagagga aaaagaaagt caaaaggaaa agatggagaa aaaaccgtct
    14461 gtgctaaaaa aattaaagga aaatcagcaa aaaatcaagc aggaagaaaa gaataaagat
    14521 ataaaggcac ttaaaaaaga taagggaatg gaactataaa aaagaggtgg tagttatgaa
    14581 tgacctcata aaaaactatg aaaatattcc tgatgagatg aaaaaagaga agcgttggtg
    14641 cctatataaa atcattcaaa gagacgggaa gaacacgaaa cttccactaa tgccaaataa
    14701 agagccggca aaatcaaatg ataaagctac atggaatagc tatgaggatt gtatcatggc
    14761 attaaaacat aatgttggcg aagggcttgg ctttttctta ggagatggat acattggaat
    14821 agatattgat aaagtaagtg atgacattat ggagtacaat acgaatcatc atgtaagctc
    14881 tatgacggct gattttttaa gagaagtttc cacctatgct gagatttctc catcgaaaac
    14941 aggactacat tttattggaa aaggagaggt gccgggagaa agaaaaagat ataaaaatct
    15001 tgaaatttat gataaggata ggttttttac agttaccggt aatgttataa aggatagaga
    15061 taggagcaaa atagaaagta ttgacagtga gctaaagccc ttatatgaaa aatatatgcc
    15121 aaagacaaat aaaattagtg ctgaaaataa aagaagtcca acggttactt cttacaatgg
    15181 ggatcaggac atattagaaa agttatttga caggggatat ttttcatatg caggagaaga
    15241 tttaagacaa atttactatg gtaattatga acgctatttt aacagccaat cggaggctga
    15301 tttttttatg ctacaaaggc tgctttacta tacaggaaat gtagaaatgg caatatcatt
    15361 tatggaaagt agcggactga aaagagaaaa atggtataaa agacgaggca ataccgatta
    15421 tatccactat attgcagata aggcgataag ctctatcaat caattttatg attgggaaaa
    15481 agtatataca tcaaaggaaa aaatagaaga aaaaagatat gaaaataaga agaaaaagga
    15541 gggagataca gtgccaagat atgaatttga tgaagtcaaa cagattcttg attttgcaaa
    15601 agaagaattt aaagaaaata tagacaggta tgaaacttat ctcaaagtga tgggaaataa
    15661 ctataaatat ccgtacttta accagcttag catatatacg gtaaatgaaa atgcaactgc
    15721 ttgtgcagaa tatgactatt ggaaaagtat aggaagaaat gtaaatagag gagaaaaagg
    15781 aatacctgtt ttagacattg aaagagagaa gataaagtat atctttgatg caagtcagac
    15841 agtaagttta aatcacaaca tttctgaagt aaagttatgg gaatatagca ataataagca
    15901 tgtagctgcc ttagatactc ttatcgatgt tttcaaagaa aaaaacagta accttatatt
    15961 ttctactgaa gataagataa atacaatcgt ttcactatat acaaagcaat tactaaataa
    16021 ggtacttaat tctttaagtg atgaaacttt aaaggaaaat aagaaagtac aaattcttca
    16081 ttttttggaa gaatctgcaa aagtatcggt atatgagaga atgggagttg cattttccgg
    16141 tgatatagaa aaattagaga tgctttcaaa tgtttcaagt atgcaggata ttgacagatt
    16201 acttttcttt acttcaaaca atgtaaaaag aatacttatg gatataagta gagaaatttc
    16261 aaaagtggaa gaaagagaaa aaatttcaga aattcaaaaa agggagcaga caaatagtat
    16321 tgcggagcgt tatactaatg ttacagatga aattaacgga aataccgaaa ttatagaaaa
    16381 tgaaaaagaa agaaatgaag gaggtttgga agatgaaaga aaccgtagta ttggcgaaga
    16441 aggagtacat cctagaaaac gagatttata caccgatcgt aaaagagagt ccattcgaga
    16501 gacagggagg gacttacaga ttggagaaaa tggaggatgg agcggaagta ttagttccga
    16561 atatgaaaat gccggagaaa ataaacgcaa gcaaactgaa ccgatttggc aaggagagac
    16621 tgaaatatct caaagaggag aaacaagagg aatatcagat tatgctgatg gaagaaactt
    16681 taatggatca tttgatagat attcaggaac aagtggagga tttcctgaat atagaagagc
    16741 cgaggatgaa agaagcttgg aaaatgacca cagaaatgca ggatcaggac tttctgaaat
    16801 acacaggact gaagaagaac ttggatatga cactaacaaa aatggctatg gaacagatca
    16861 tttgggtata gatgagtatc gtaaagaaaa tatacagaag atagaacaaa atcatgtaga
    16921 aaatgaggaa aaagaagtcg agaggacttc tttttctttt gctcaaaatg taggagttca
    16981 aggaagattt gaattaccaa tgcagcaaga agagattggt gctgttttaa ttcatggagg
    17041 aaatgaggat aatttacatt taaaggtttt agccgaatat tctaaagaaa aaagcatgga
    17101 agaattagct gattttcttc aaaaaacttt tcaaggagga aatggatatg aactaaatgg
    17161 aaataaggtt tgtgcttggt atgaaatgga cgggatacat ttatccaatg atgtttcctc
    17221 aagagaaaat cctatgcaga ttttaccatg gaaagatgca gcaatacgca taggagaatt
    17281 gattgattat ggaaaataca gtacaaatgt ggaggtagca gaagcctttt cttttgaaag
    17341 agcagaactt tctgaaaagc tgtggttttt aaaaggagat ctaagtgatg aggtaaaaaa
    17401 tcagtttttg ccaattctaa atgaaaaaca aagaaacgga tatcctgaaa aaacagagta
    17461 tcttacaaaa aaattggaag ataaagagtt tagagtgaac ttaaaagagg agtatataga
    17521 gttttttaag gcgtataagg agaactcgaa tgttttaaga tttcataatc atgatttaga
    17581 tgatatatca aaacgattag atgatttgga actgccaaga aaagaattta cctcaacact
    17641 tatagaatta ccagcaatac agggatttat cacagaagat gaaattgata gatatttaag
    17701 cagcggtagc aatgtatccg gcggaaaaga aagaatatat aactttttta gggaagccca
    17761 tactaccgaa gaacgagcaa attttttaaa agacgagtac ggaacaggag gacagactca
    17821 tgctttatca agggcaagag gaagtagtga gtggcacgat gctaagggga taaaacttga
    17881 aaaagaaaat tgtaaggata ttattttgaa atggaatcag gttgtaaaaa aaatagataa
    17941 ccttattgaa aatggaaaat atattcaaga agatgtatat acagagcaag aaagcataaa
    18001 aactgaggaa gaatattttg atgaagatac ctatacggaa caaaactcta aagaaaatga
    18061 acaagattgg caaagagaac aggaaatttt gctgattcaa gatgaaagag aagtatctta
    18121 tgaagaggcg gaggaaatat atgaaaggca agcagaaata gaacataatg cctttgcaac
    18181 cggtgtagag aataacatat cgtcaactca aagtaacaag gattattgga ttgtagaatt
    18241 taatgaaggc tcaaatctga tagaaaaaaa ttatgccgga gaagttgtta cgaaaaaatt
    18301 gcttgatgaa atcaaggtgc ttgacgaaaa aattagagtt cataataaga ctgtcggtga
    18361 agatgaatac ggagaaatga cagatgaatg ggtaggttat tctaaattct attttgacca
    18421 tattgtagac gggaaagtag aagaacactt cagaatggat atcggggatg gaaatgaggt
    18481 aaaccaaaga gattttcaat atctttatga gcagattgaa ccggaaaaag aaaataaaga
    18541 atacgggatg gatagtatag atagtgtcat aaaagatatt ttagaaaaag aatctatgac
    18601 tgtggtatca agcaaagatg attatataaa gttatttcca tattttagaa actttgtata
    18661 taccgatggt ctaaggcttg atgaatataa tccgtttgaa gatgatgaaa atatttcgga
    18721 tttaattcga ctgacttttt tccaaaataa tgatggagaa tatagggtag tctataacaa
    18781 tgcggacagt ttactgtatt caagcaatgt tgactatttt ttggagaaaa tagaggctga
    18841 aaaggtaagg ttagaagata atatagctga gataccgaat gaagataaaa ttgccgttaa
    18901 ggttgggaat tactatgctg ttgtagaaaa agaaagagta aaggatatat ccttagaaga
    18961 aacaggagtt cgtgtttatc cgaaagaaaa taactttgag ggaaaaattt acccattgta
    19021 tcgtggcagc acctttgaag aaagtgcaaa aatagataaa cttttcgatg agattgcaat
    19081 aggcatgaaa gaggtcaatt tgaccgattt aaatgatgtt ttttatcttg aaaatcaagg
    19141 actttatgaa atttcatcgg atagggtaac ggaagaaaaa gccggatacg attttgaagt
    19201 ggcaagtttt aatgaacagt ttcctgatta ctataatgac atttatgtat ataacagaaa
    19261 tttaaaaata gatggtgcta atcaaaacat tgcatatatc aatagagaaa atgaaataca
    19321 ttttaatgta aatctaccgg aagaagaaaa agcaaaggtg cttgaaatta gagataagaa
    19381 agaagtctta tcaactctta tttttaaaga tgtaaaggag gtcggcgaat atcagtttca
    19441 tccacaaagc gaagaattta tcttaaatga attgagtata tctgaagaaa aattaaaagc
    19501 accggaacat ataacagata agattgataa gaaagaaggc tatgaggctg aacttgtttt
    19561 ggatatgaaa aacaaggagt taaggcagca tttaagatat aacggatata tgttaagtag
    19621 caatgtggcg gtttcctatg atagttataa agcaatactt aaaaatcttt cttatctgct
    19681 tgatgataat catagaaata ttatgcttac cggctatgtc aacgaacaga ttgaaaagga
    19741 taaagcaaag gaagaaagaa aagaacctgt atatcaagag ggaatgaatg taaggtatca
    19801 aggcaaagaa tatatcattt cagaaattca agactataaa acatataaaa caataaagct
    19861 agatgattca gaaggatatt taaacggctt tataacgggc agtgaaatta ttccttttag
    19921 aaatgaaaga gaacttgatt tggaaatcat atctacaaca gagaagttac aagaacaaag
    19981 tataaatggt gaagatctta ttctgttaga tattgaagaa tataacaaaa aaggactttc
    20041 cgttatcttt caaaataaag agtatgaaat tacaggaaat aattttaatc ctgtaggaat
    20101 gagcaggtta caacttgtct cgaatacaga aaaactgatg acagaaattt catatacacc
    20161 tcaaagaccg gtcgcaaatc tttatgcaaa aaaagatctc cttgaaaggt ttaatttaaa
    20221 tgagaaaaat agtgaaaaaa gtattgaagc aaagcaaatg tctttaacag atatatttga
    20281 ggaacaggat acaacaaagg gaaaagaaga aatttcaagt gagaaagaac gtgtacctgt
    20341 caatataggg gcaaaggtaa tctatcaggg agaagaatat acagtaagtg cctttgagta
    20401 taataatatt ttagagaaaa atgatatatg gctaaatcct gtatcaaaaa ataatcatca
    20461 aattccgatt gtaagttttt ctgacagaga agagctaaat gaaaagctca ttgttataga
    20521 taccaatctt aacttaggag aagacaagtc ggaactgtta catcatagtt tagatgtaat
    20581 aaatgataaa ggttctgtga ttgccaatca gtttattgta aaagtcgata atcaaaacag
    20641 ggaacttaca gtatatagtg aacaaaatcc taatagtcat agagaatttg aactttcttt
    20701 tgattatcta aacgggcttg ggcaaattga cggagatgga aataatctaa aacttacaaa
    20761 gcataaaaaa gaaaccattg ataaaaaatt gaaaagttat cattcttgga aagaagatgg
    20821 ggaaaaaaga ggaattccgg gaatagcagg ttcttctatt acttcaccta ttactgatga
    20881 aatgttttgg cagatgaaag aatatgaaga aaaattaaaa gaggaggaaa gatacgcccc
    20941 tgatgataag tatttgggag gtattcctcc aatcaattac aaaatcacaa aagaagatga
    21001 aatcttgccg ccgtccgaaa ggcttaaaaa taacatagaa gccatcaagg tattaaaaga
    21061 aattgaggaa agacatagtc atgcaacaaa ggaagaacag gatattttga gtagatatgt
    21121 cggctggggt ggactttctg atgtctttga tgaagaaaag ggaggacaat ggaaagatgc
    21181 aagagaattc ttaaaagaaa atctatcacc gtctgagtac gatgcagcaa gggaaagtac
    21241 ccttacagcc ttttatacac cgaagattgt aatagacagt atctatcaag ccgtattaaa
    21301 tatgggattt gaaagtggga atatcttgga accaagtatg ggaactggca gatttatagg
    21361 caatcttcca gacagcatga aaggcagtaa attttatggt gtagaacttg acagtataag
    21421 tggtaggata gcaagtaggc tatatcctaa tgctaaaata cagatcaaag gttttgaaga
    21481 aacgactttt tcaaataatc tgtttgatgt agcggtggga aatgtaccgt ttggagaata
    21541 taagatagtt gatcgtgagt atgagaaaaa caattttctt attcacgatt ttttctttgc
    21601 caaaaccttg gataaagtac gttccggtgg agtagtagcc tttataagtt caagtggaac
    21661 tatggataaa aagagtgaag atatcagaag atatatttca gaaagagcag agtttttagg
    21721 agcaattaga ctacctaata atacttttaa aggcgaggcg ggtacggaag taacaagtga
    21781 tattattttt cttaaaaaga gagatcgact ggtaaaactt gatgaagaat gggtaaaact
    21841 tggcactgac gaaagaggac tgacatataa caaatacttt gtagataacc ctgatatggt
    21901 acttggaaat atggaagaaa tatcaagcag atttggaaca agtcttgcct gtgttgcaga
    21961 tgaaaatagt actctgaaag aacagctgga taccgccatt aaaaacatta aaggaagtta
    22021 tgagaagata gaattaaata atgaatttga agtggaaacc attccggctg atgacagtgt
    22081 gaaaaattat tcttatgcag taattgatga taaggtatat tttagagaaa attccgttat
    22141 gcaaaaattg aatttaaata aaaatgatga ggaaaaagta agggcatatc ttggaataga
    22201 aaaagcatta agacaggtaa ttgcttatca aaaagaagat tattccgata cggaaattaa
    22261 ggagaagcaa ggggagttaa atcgtattta tgatgagttt tccaagaaat acggaatttt
    22321 aaacagtaag gcgaataaaa aactgtttcg tgaagacgct aattattctt tactgtccac
    22381 tttggaaaag ctggataaag aaggaaactt tatagaaaaa tccgatatct ttacaaaaag
    22441 aacaataaaa aaagcagtag ccatagagca taccgacaat ctgacagaag cacttatcct
    22501 atctatttct caaaaaggga aagtcaattt cgagtatatg gaaaagctca ctgaaaaaac
    22561 aagaggagaa atcattgaag gattaaaggg agaaatattc ttaaatttag atggatttga
    22621 tccaagtgat acgactcctt tttcttcagc catagacttg ggagattttt caagatctta
    22681 cgtaactgct gatgaatatt tatctggaaa tatcagagat aaaatagaag taatagattc
    22741 gtatataaag aatgtagaac atgaatttga acaaaatgaa cagcttgaaa atattgatgc
    22801 agatgtactg aaacagggta gtgagacttt aaaaaaagaa ctgtccagtt taaattacca
    22861 aagacaaaag ctgctagaag taatgccaaa ggagcttgag gcaagtgaaa taaccgttag
    22921 aatgggagca acttggatac ctgagaaaga ttataagagc tttatgttcc atcttctaaa
    22981 aacatcggca tctaatagat ggaatattga tattaaatat accaatttta caggggagta
    23041 cagagttgaa ggtaaaagta tagataaagg aaacgacctt gccaatttca catacggaac
    23101 aagcagagta agtgcatata aactgattga agatacatta aaccttagag ataccaatgt
    23161 atatgatcaa gtcattgatg aaaacggaaa gaaaagttct gtactaaatc aaaaagaaac
    23221 gatgcttgca agaagtaaac aggaaattat caaagaagag tttaaaaatt ggattttcga
    23281 tgatatagac agaagaacaa ggcttgtaaa agaatacaat gagaaattca attcgataag
    23341 gcttagagaa tatgatggaa gtaatttaac ttttgacgga atgaatcctg aaatagagct
    23401 tagacctcat caaagagatg cgattgctag aggacttttc ggtggaaaca ccctacttgc
    23461 acatgaagtt ggagctggaa agacttttga gatgatagga attgctatgg agtctaaaag
    23521 gcttggaatg agtaacaagt caatgtttgt agttccaaac catattgtag aacagtttgg
    23581 tagagagttt aatgaactgt atccggcagc aaatattctt tgtgcaacag aaaaagactt
    23641 tacaccagat aaaagaaaaa gattttgctc aaggattgca accggtgatt atgatgcggt
    23701 aattataggg cattcgcagt ttgaaaagat tccaatttca aagcagcgac aggagtatga
    23761 acttcaaagt cagattgatg aaattataga ttttatcgaa gaatataaaa ggaatagaga
    23821 tcagaaattc accgttaagc agcttgaaaa aacgaaaaaa ggactggagg caaaactaaa
    23881 gaaattaaat gatgattata gaaaagatga tgtcgtaacc tttgaagaat tggggataga
    23941 caagctattt gtagacgaag ttcatgcttt taaaaatttg tacgttttta caaaaatgcg
    24001 taatgtagca ggaattacaa ccacagattc tcaaaaatca agtgatatgc tgatgaagtg
    24061 cagatatatg gatgaaatta ccggtaataa gggtattgta tttgcgacag gaacccctgt
    24121 gagcaattct atggcagagc tttataccat gcagcgttat ctccaatatg acgaacttaa
    24181 aaaaatgcac ttgcaacact ttgattcttg ggcatctact tttggagaaa ctgttacagc
    24241 aattgaactt aatcctgaag ggaacggata tcgaagcaag acaagatttg caaaatttta
    24301 taaccttccg gaactgatga atatggtcaa gcagtttatg gatataaaga ctgctgatgt
    24361 attaaatctt cccgttccaa atgctcatta tgaaacgata aaaaccaaac cgacagaaga
    24421 acaaaaacaa atccttgaaa ctttttctga gagagctgat aaggttagag gaaaacaggt
    24481 ggattcctct gtcgataata tgcttctgat tactaatgac ggaaagaaaa tggcacttga
    24541 ccaaaggtta attaatccat tacttcctga tgatccgaac agtaaagtaa atacctgtgt
    24601 aaataatata ttcagtattt gggataaata tagggatgag aagtccacac aattagtttt
    24661 ttgtgatatg tcaacaccat caagtgaatt taatatttat gatgatataa aggagaagct
    24721 gacaaaaatg gggattccta aaaatgaaac agagtttatt cataacgcaa agaacaacaa
    24781 agaaaaagat aagattttcg ataaggtacg aaagggtgaa attcgtgtgc ttctcggttc
    24841 aacgcagaaa atgggagcag ggacaaatgc tcaaaataaa ttgattgcta cccatgatct
    24901 cgatgtaccc tggaggcctg cggatttgga gcagagaaaa ggaagaattg taaggcaagg
    24961 taatgaaaat gatgatgttc atatctttcg ttatattacg gaaaatacct ttgatgcgta
    25021 tcttttccaa acacttgaaa ccaagcaaac ttatatatct caaataatga attcaaagac
    25081 acctgtaaga gtagcggagg atattgatga agctacatta aattatgcgg agattaaagc
    25141 acttgcaaca ggaaatccgc ttattcgtga aaaaatggac cttgatgttg aggtaagtaa
    25201 acttaaaatg ctggagtcca attttaaatc caacctatat aaaatggaag ataaggttgt
    25261 aaaagtatat ccaaaagaaa ttaaaagtct aaaagaaaaa atagaaaatt tgaaaaagga
    25321 tatagaaaaa gtggaaccgt atagggagga aaaactagaa aaatatgatc agactacttt
    25381 agaaaatatg ggtgaaaatg aaaaacaagt ggggataaaa gcagataaag aagcaatatc
    25441 aaaattcaca tctttaactt taaatgggaa aaaatatacc gataaaaagc aagccggaga
    25501 gttcttaata aacaagataa aaggaataaa aaaattagat gattttcgtt ctgaggaagt
    25561 aaaaatcgga gaatatagaa atttcgattt gttcgcatat tatgacaggt tctccaatca
    25621 gtataaattc aatctgaagg gagaagaaaa tcattatggg gagtttggaa cggatgaaat
    25681 cggaaatatc acccgaatgg ataatgtact tgataggatg cctgagagat tggagcagac
    25741 acttggaaaa cttaaagata ccgagaatca acttgaaacg gcgaagcttg aaataaaaaa
    25801 gaaatttcca caggcagagc ttttaaaaga aaagacgtta agacttgctg aggtaaataa
    25861 tttgcttgat atgggacaaa aaggagattt aaaagaggag aaaaatccac ttttggaaga
    25921 agtgaaggaa gaactgattc attttctaaa taaagaatat gatgaagcac acagtataga
    25981 agatttcgat acaatgtttc ctgacttgac agatataggt ttggcatata cgactacacc
    26041 ggatgaaaag catgagatac agacaagtct tgatttaatc aattacaaga tgaacactta
    26101 tgtagacaat actttaattg acagttttca gtatacttac gatccactta atgcaagtga
    26161 tacgaaggaa cttatacaaa tcaaaacgaa cataggtttt tgggatttta atgagctggt
    26221 atatgtggat gaagaaaagt taaaagcatc acttggactt gaaattgatg acgatggtaa
    26281 tttctatgat ccgctttcaa aggatatgga tttagatgga gtaatggaca ggtatgatgc
    26341 agactttaga gatagtaaag tacaaagttt tggagatttg gataaaaaag aaaaagcatc
    26401 cgtaatggat aggcttggat acttcaaaga aaagataaag aaaggaggcc tacaaaatga
    26461 aaatattgat agaaagatag agtgtaagga ggaggttaga tagttggaat atcacaaaaa
    26521 tattagagca acggatagag aaatgcagaa actttttgaa aatgaggagt ataactattc
    26581 cgtaagatat tttgaaaaaa tagaagaaaa cttatttaaa acgataattc gcacaccgga
    26641 gaatatagag tttccaaaat ccaaaacctt gt
//
LOCUS       DARYLD010000030        25286 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYLD010000030 DARYLD010000000
VERSION     DARYLD010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25286
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(122..1381)
                     /locus_tag="TU651_001099"
     CDS             complement(122..1381)
                     /locus_tag="TU651_001099"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0897108.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(1697..2902)
                     /locus_tag="TU651_001100"
     CDS             complement(1697..2902)
                     /locus_tag="TU651_001100"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL0897109.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(3235..5454)
                     /locus_tag="TU651_001101"
     CDS             complement(3235..5454)
                     /locus_tag="TU651_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0897110.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            5981..6922
                     /locus_tag="TU651_001102"
     CDS             5981..6922
                     /locus_tag="TU651_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL0897111.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(6897..7100)
                     /locus_tag="TU651_001103"
     CDS             complement(6897..7100)
                     /locus_tag="TU651_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL0897112.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(7481..9157)
                     /gene="dnaX"
                     /locus_tag="TU651_001104"
     CDS             complement(7481..9157)
                     /gene="dnaX"
                     /locus_tag="TU651_001104"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL0897113.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(9157..9654)
                     /locus_tag="TU651_001105"
     CDS             complement(9157..9654)
                     /locus_tag="TU651_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL0897114.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            9834..10604
                     /locus_tag="TU651_001106"
     CDS             9834..10604
                     /locus_tag="TU651_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL0897115.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(10786..11058)
                     /locus_tag="TU651_001107"
     CDS             complement(10786..11058)
                     /locus_tag="TU651_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL0897116.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(11081..11707)
                     /gene="udk"
                     /locus_tag="TU651_001108"
     CDS             complement(11081..11707)
                     /gene="udk"
                     /locus_tag="TU651_001108"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL0897117.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            11803..12897
                     /locus_tag="TU651_001109"
     CDS             11803..12897
                     /locus_tag="TU651_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0897118.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(13162..14448)
                     /locus_tag="TU651_001110"
     CDS             complement(13162..14448)
                     /locus_tag="TU651_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL0897119.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            14870..16033
                     /locus_tag="TU651_001111"
     CDS             14870..16033
                     /locus_tag="TU651_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0897120.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(16156..18774)
                     /gene="alaS"
                     /locus_tag="TU651_001112"
     CDS             complement(16156..18774)
                     /gene="alaS"
                     /locus_tag="TU651_001112"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL0897121.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(19130..20131)
                     /gene="prsA"
                     /locus_tag="TU651_001113"
     CDS             complement(19130..20131)
                     /gene="prsA"
                     /locus_tag="TU651_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL0897122.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(20194..20901)
                     /locus_tag="TU651_001114"
     CDS             complement(20194..20901)
                     /locus_tag="TU651_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL0897123.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(20984..21622)
                     /locus_tag="TU651_001115"
     CDS             complement(20984..21622)
                     /locus_tag="TU651_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0897124.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(21672..22304)
                     /locus_tag="TU651_001116"
     CDS             complement(21672..22304)
                     /locus_tag="TU651_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL0897125.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(22294..22851)
                     /locus_tag="TU651_001117"
     CDS             complement(22294..22851)
                     /locus_tag="TU651_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0897126.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(23050..24852)
                     /gene="pepF"
                     /locus_tag="TU651_001118"
     CDS             complement(23050..24852)
                     /gene="pepF"
                     /locus_tag="TU651_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0897127.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(24842..>25286)
                     /locus_tag="TU651_001119"
     CDS             complement(24842..>25286)
                     /locus_tag="TU651_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL0897128.1"
                     /translation="MIHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMD
                     KHLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHE
                     DLSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT         7317 a         5880 c         4841 g         7248 t
ORIGIN      
        1 ggatagacag ggggttctta aaaatcaaaa gcccctaaaa ccactctcat accaagcagt
       61 cttaggagct ctaagcattc atgtcaggtg ataatcatta ggctatgaaa gccttcagtt
      121 cttaatcctc aataagctga atatcagccc ctaaggctgt tagcttatca ataatgttag
      181 catagccacg taaaataaac tcaatattgc taatctcggt tttaccctga gccattagac
      241 ctgcaatcac caaagcagca ccagcccgca aatcagttgc cttaacctgt gccccactga
      301 ggcgattaga gccatgataa acaatttggc tgccaagaat ggcaatatct gctcccatac
      361 gagcaagctc tggcacatgg ttgacacgct tttcatatat cgtatcaatg atactaccac
      421 gaccctcagt ccttaaaagc agaggagtca aaggctgctg taggtcagtg gcaaagcctg
      481 gatagggaga ggttttaata gtgactgctt tcaaggcttc ctgcttttcc acaaaaatag
      541 aatcctcttc aaccgtcatt ctcacaccca tttcctctag cttagcaata aagctctcta
      601 agtgctcgta aaggacattg gtaatcctta ccccactacc aacagcggct gccaaggcaa
      661 tataggtacc agcctcaatg cgatctggga tcacctgatg tctggtgcca tgaagccttt
      721 caactccctc aatcgtaatc acatcagtac ctgcaccacg aatatgcgcc cccatgttat
      781 ttaacagtgt cgcaacgtca ataatctcag gctctctagc tgcattttca ataatggtct
      841 taccctttgc ctttgtcgca gcaatcatag tattaatggt agcgcctaca ctgatagtat
      901 ccatgtagat atgagcgcca tgaagctgct gagcctctgt catcaggtgc atgcttgctc
      961 cctcataaga tatctgggcc cccattgctt caaaagcctt cagatgaaga tcaataggcc
     1021 tagggcctaa gtcacagcca cccggcaagc ccacaaccgc ctgcccaaag cgtcccaata
     1081 gactgccata aaaatagtaa gaggctctta ggctgttaat tttaccataa ggcataggaa
     1141 tatcttgaac ccctctgggg tcaatctcca aggtatcccc ctgataggtc accatagctc
     1201 ccatgagctt catgatttca ataagactgt caacatcact aatagctggt accccatcta
     1261 aagtgacaac atcgtctgcc aaaataatcg caggaatgag agctacaacg ctatttttag
     1321 cgcctgaaac tgccacctct ccggataagg cttttccacc attaataata atttttcgca
     1381 tactttcaaa actttctgat actagaattc aaccttttta ttttatcaca aatagcggtc
     1441 tattacaatc acctcatcac cagctgctgc aacaggctta acaacctgcc tcttgatcac
     1501 ttttcataac aggtttttga gaagccagac tcttatctgg atctttcttc tgctgcgcag
     1561 gcctttttgt ctttcatagc cgccaagcct gacaagtttt gctggactaa aaaagctccc
     1621 aaccagcagc acagccgcta gctcaggagc tattatacct ttaagtcaat catcaactaa
     1681 ccggcgctca atctgcttaa gcaccctctg acagtgctgc caccgcttct gtcaatggag
     1741 ataccttgtc caattgttcc caaggcaggt caatgtctgt tcgccccatg tgcccatagg
     1801 ctgctgtctg cctatagatt ggacgcttga gatcaagcat cttaatgatc cctgctgggc
     1861 gcaggtcaaa gacctgacga acagccgctt ccaaaatact ttctgacact gttgatgtcc
     1921 caaaggtatc cacacgaact gaaactggct gtgcaacccc gatagcatag gctaattgaa
     1981 cctctgcttt acttgcaagc cctgctgcca caaggttttt ggcaatataa cgagctgcat
     2041 aagaggctga gcggtcaacc ttagttgcgt ctttaccaga gaaggcacca ccaccatgac
     2101 gcgcatagcc accataggtg tcaacaatga tcttacgacc agtcaagcca gaatctccct
     2161 gaggaccacc aataacaaaa cgcccagtcg gattgataag gaatcttgtc ttctcatcta
     2221 gataatgggc tggaataaca gccttaatca cctgctcaat catatcttga cgaatctggt
     2281 cattgcttac ttctggatca tgctgggttg atataacaac tgtatcaaca cgaacaggct
     2341 tatcatgttc atcatattcg accgtaacct gtgatttagc gtctggacgc aaatagctga
     2401 tctcacctga ttttcgcagt gtcgccaaac ggcgtacaag ctggtgagat aaggaaatcg
     2461 gcagtggcat tagttctggt gtctcatcaa ttgcaaagcc aaacattagc ccctgatccc
     2521 cagcaccaat cgcattgaaa tcatcgcttt gtccttcacg tgcttcaagt gcttcattaa
     2581 cgccttgagc aatatctggt gactgctcaa ccagagatgg atgaacaccc actgattctg
     2641 ctgaaaagcc atattctgcc tcagtatagc caatctcagc gatggtatca cgaaccacac
     2701 gattaatatc cacataggca gttgttgaaa tttctccaaa aacgtggacc gagcctgtgt
     2761 aaacgcaggt ctctgcagca acgtgtgcct ctggatcctt ggctaaaata gcatctaaaa
     2821 tagcatctga aatttggtct gcaatcttat ctggatgccc ttcagatact gattcagacg
     2881 tgaaaagttt acgttctgac ataaaaatgt ccccccttaa aaagaatgat acccaccagc
     2941 acacatgcca gataggattt tcctagcctc actcatcaag ccagccgcca atacaaaagg
     3001 actgtatcca agctagccta tgactaacgc ttagcgagtt acaaagtacc ggcttttaga
     3061 ctgctatcct cagataacaa agccgtctta tcgggactta ataacttatc tattatacca
     3121 cttttagcgg gatttgtaag agctccatca gcttttttct caaaataaga aaaggaatac
     3181 cgctacaggc gtattcctcc tcttaatgtc gtgataatca gcgcaagcta tcgattaacc
     3241 atggtggtgc tcatcgtgat catgatgctc atggtcatgc ttatctgctg cctcttgatc
     3301 agtatcagcc ggcttatgct cgtcttcaac agcttctgct ggtgtggcat tatttagact
     3361 accaccctct gctgccttga agttcttgat aattccttgt gggaattgtc cgctttcagc
     3421 agctagctcc tcagctggga agtggttacc atcagcctga atgtatttca gggtttggtt
     3481 aggctccttc aaggccaagg tgttaatctt gttacgatta acattaattg cttctagggc
     3541 gagataattg ttgacaccct caaaattagt cagctggttc tcttcaaggt taagagactg
     3601 taatgagctt tgtgtacctg gtaaggccaa gctattaatc atgttctggt tagctgatag
     3661 ctgaatcagg ctcttattgt gctcaagacc tgtcaagctg ttaagcttgt tttggtcaac
     3721 cactagctgc tctaatgccg gtagatcctt gacaaagcta aggctttgta aattaacctc
     3781 cttggcagtg atttccttga gagcagagga ttttaaggtt gacaaatcaa ggtcagggtt
     3841 gtttgacaca aagagtttgg tcaattgtcc cttgtttgac aaggcactca agtccttaat
     3901 ctgattgtgc tctaggctga cagcgactag cttttgagca tttgccaagg cagaaagatc
     3961 tgtaatcttg ttaaagtcaa ggttaacgga ctctaggttt ggcaattctt tcaaaataga
     4021 aatatctgtg atatcatttc ctgctgccga aattaccttg taatgcggaa aggctttaag
     4081 gaagctcaaa tcagaaacac cattttgaga aatatcaatt ccttcaagcg ttggcaggtt
     4141 cttcaagaaa tcataatttt taatgccggt ctgtgtcatc cacaattgtt tgaggttctt
     4201 gaactggtag actggggtaa tatcagtgat tggggtaaag ccaataccta aaatctgtat
     4261 attaggcatc aggtttaaac ctgcccgctt aagaggatcc ttaatctcac cgatattgag
     4321 gtattcaaca gtcgccaacc atgccttcat tttctctagg tctcgctctc ttgatggaaa
     4381 ctcagttggt gcatttgcat ggataatgga cgaaatcact tcctcatcaa agccaagctt
     4441 tctcagagtt gccataccga ttctatcctt agcatgcgga tctactgcat gaggatcaaa
     4501 aggttttgat aaatcaatat cgtcaatata ggttgcatga cgatggtcac catgtggata
     4561 gtcaagaatg ataccttctt ctgtatgctc cacacgaatg ctgtcctcag gaatatttaa
     4621 tgacttagcc aaatatgctt ttttcaaagc aatcgttttc tcaagatcac tttgtggctt
     4681 agctggtgct tcttcctttg gctgttcgat taaatgcttc cacttgctgt tacgcaagct
     4741 ttcataagtg actaaatgat tgtggccatt gtgatcaaca atcaatccat atgatgttcg
     4801 accgacaata cctgtcccgt caaacaagaa gccatcactt gttgggtaat caacacctgc
     4861 aaattttcca gacggtgatg atggagctga tagtggcaca tggttaggca ctggataagc
     4921 tacctgacca cctagtgagc tttttaggat atagtggtaa tgatcaccat gacggacaat
     4981 atagcccaag gcgtcctcag ctacaatatc agctgggtta aacacatagt gatggtgcgg
     5041 gtcattagca ctagtatggt gatgacctga tgctgccttg gtctgctcag gcttgtttag
     5101 gtcagcgtcc tttggaatca ggtactcaaa cttgctgccc ttgagatctg cataaaaaat
     5161 aaaatgcgaa tgcccattat gctcaacaac aataccgttt tctgttctag ataagatttt
     5221 tgaatccttg gtcaagataa aaccgtcatc agttggaaag tcaatccccg ctactccctt
     5281 acggtctttt cttgtttgct taaccttttt agactgtttc tttttggtcg cttttttagc
     5341 tgtctgtttt gtcttaggct gatttgttgg ctgctttgtc gactgacaag ctgtcagggt
     5401 caggtgacaa gccataaaca ggctagccat tagcattaat tttttacttt tcatctttcc
     5461 tccataaatt aactggttaa ataagatatt aactagttaa atataccaaa aaaacaaata
     5521 atttcaactg ttttcttatt tttaattcat tctcattcaa caatcatagt agcttggcta
     5581 ggttggcaga aaaatgagcc tctcctactc tcatcaaata aacagatagc cttaatgatg
     5641 gctgagataa cagcatacaa agtcgttaaa gtcacttgta agaaaaagaa ggacatatct
     5701 taccaccact atcttgctca tcaaagccct acggctttca gacaaaatct tcataacagc
     5761 ggaaaggctg atgaagcagc tcagacaaaa agagcaagct ccttaacgtc aaggatcaga
     5821 gatcagcaca aaaataacag caggctacat taagaactgc aattccttga aatagaattg
     5881 cttttttaca aaaaaatcgt ctccctagac tgttccatca tctcacgtca tttgtattat
     5941 ttgctcttga aatccagtca ttttatacta tactagaatt atgaagacat ctgaaaaaat
     6001 ttaccaatta ctagcttgca gcgacgacta tgtcagtgga gaatacttgg cagagcagct
     6061 caagctttct agaacctctg tctggaaatc catcaaaagc cttgaaagtc aaggccttca
     6121 cattgaatcc ctcaagcata agggctatcg ccttattcaa ggagatatat tgctgccaga
     6181 gctcatcagc caagagctca acatgccttt atcttatcat gagaaaagcc agtcaacaca
     6241 gctagacgcc aagcaaggaa tcgagctaaa gcatactgct cctaggctct atctcgctcc
     6301 aagtcagtat gcggccaagg ggcggcttaa tcgccaattc tttgcgtcac ctcatggcgg
     6361 catttacatg tccttgcatc tcaagccaaa tgttccttac gcagacatgc ctccttacac
     6421 catgatggtg gcctctagta ttgttaaggc tatttcaaga ttgaccggta ttgacaccca
     6481 aatcaaatgg gtcaatgata tttaccttgg ccataaaaaa atcgccggta tcctgactga
     6541 ggccattacc tctgtggaaa caggcgtcat tactgatgtg attattggcg tagggcttaa
     6601 cttttttgta accgaatttt ctgaaaacct caaagaacga gcaggctctc tttttagcaa
     6661 caagcctagt attactcgaa atgccctaat cattgacatt tggaagctct ttaccacaat
     6721 accaatcaag gaccatatta aggtctacaa agaaaaatca cttgtccttc aaaaacaagt
     6781 gagcttccaa gaaaatgatc gtcaaaaaac agcaactgcc attgacctga ctgatgaagg
     6841 acacctcatc gttcaattag acaatggtca gctacaggtc ttaaggagcg gcgaaattag
     6901 tctttcttcc tggggggatt aacagcatta atgatgtttt tggtaaattg gtcaatagca
     6961 taagcacgcc ttaaatctct aaagagcaaa agaccccaaa acagagcaaa aatataatcg
     7021 cctgaaaata ataaatcgct gaaaaaataa gcttcaaagg cacaaatgaa tgccataaac
     7081 ataaattgtc gaatagtcat actactatta taccaagaaa actaaatttc cactaacgat
     7141 tttcacgcag cttgaagaaa aaggcagtta gcctgcttca agcttttttg ctgctctttg
     7201 atagcctgta acagtcaaat aaaaaagagc tcactctaaa aacgacgcca aaagccagct
     7261 tgattgctag gcttgtagtc aattgtctca aatcagtgaa tcactaagcc ttataagaac
     7321 tcagtcattg ggtcacaatg acacctagct ctaagcagca aaaaagagaa ccacaccggt
     7381 cctctctagc ttggcttgtc agctatctat tagtgctgac aatgagccct gtcatctcct
     7441 tattctagac aattgataca ctaccaatca tcagctagcg ctaatcctct atgagatgaa
     7501 tcttatcagt taaaaagtca aacccctcag gcatgtcaaa ggtcgcttgc tcagactctt
     7561 tggctgtctc ttttttggtt ttgatggtca tggcaaactc cgagcgaata tggtggaagt
     7621 ctgcctttgg tactgccaag atatgaggag aaaaccctgc tgccttactc atgatattcc
     7681 caaacatatc attcaaatcc tgacgcttca tggcctgctc agcgttaaag gcggcctcaa
     7741 aggccaaaat agcattttca ctattggcta aaacaggctc cgagcctagt aacaaagctc
     7801 gatcctgtgc agaaatacta tctaaaatct cattccaagc actttttagc gcttctaaat
     7861 attgtcgtga ctgctggcta tcttgaacag tttcctccat gattttcaat atcttttccc
     7921 gatcaacctt gtaggtaaag gcctttggct tgatggaatg agctggtgta gcctgcgcag
     7981 ttagaccctt ttgagcctgt agctgtgata tcgtctccct cagctgacta atctcatgct
     8041 tcaagtcatc aacatcagct agcaggctag acggtatcgc agtgtctgct gcttgtcctt
     8101 gctctgccag ctgaatggtc atcatttcag cgtagattct aggatgggtt ccttttttga
     8161 tctcaggcaa atgcttggtt actgtagcaa tcattgtaaa aagctgatca aaagacactg
     8221 caaggttatc atcaaaaaga gctgactgcc tgtgatgatc accacctgat ttcacaatga
     8281 gcaggtctct aaaataggtt agcagatccg ttgcaaagcg actcatgctc ttgccactat
     8341 cataaattgt ttctagatta gctaaggcct gacttgtttt ttgcctgatg agatgctgaa
     8401 cgtagtcgtc taaggccgaa atagaaatag agcctgtgat ttcttctgca atagcaagcg
     8461 tcactcgatt gtcaaaggat aggctcaagg cctgatctaa aatggatagg gcatcacgca
     8521 tgccaccttc tgctcgtctt gcaattaaat gaagcgcctc tatttcatag gctatgccct
     8581 ccttgtccag tatcgccgcc aaatgctcac aaatagctgg ctgcttaatg gctttaaatt
     8641 caaatcgctg gactctagac aaaatagtag ctggaatctt gtgtagttct gttgtggcta
     8701 ggataaaaac cacattgtca ctcggctctt caagggtctt taggagcgca ttgaaggccc
     8761 ctgttgatag catatgcacc tcatcaataa tataaacctt gtaggttgcc cggctaggag
     8821 cataggttga cttatctcga atatcgcgaa tttcatcaac accattatta gaggcagcat
     8881 caatttcaat cacgtcctcc aggctgccag ttgtaatatc tcggcaaata tcacaatgat
     8941 tgcagggctc tcccttgacc tgattagggc agttcattgc cttagcaaaa attttggctg
     9001 cgctggtttt accagttcct cttggacctg aaaagaggta agcatggctt atcttttctg
     9061 actcaacagc ctgctttaag gtggtcgaaa taactgactg cccaaccatt tcagcaaagg
     9121 tctggctacg atacttccgg taaagggctt gatacattaa ttctcaactc caaacatgtc
     9181 aaaacgaaaa gatgtatttt ctagtaataa ggctacaaat tgctctaaat agtcttgatc
     9241 tatctgatca taatcagcaa caagactgga atccaaatcc agaacaccaa caagcctgcc
     9301 agccttaagc attggcacaa caatctcgct catggctgct gaatcacagg aaatgtaatt
     9361 agcatgcttt ttgacatcat caacgatgat ggtttgacca gattgagctg attctccaca
     9421 tactcccttg ccaagcttga tatgcacaca ggaaaccttt ccctgaaagg gaccaaggat
     9481 caattcttga ccatcaaaaa ggtaaaagcc tgcaaaaaca gaatgaggca gggtcatttt
     9541 taagagggca ctagcattag agagattggc caaggcattg ctttcattag aaaataaggc
     9601 tttagcttga gccaataata gctgataatg ttcaattttt gtcgtcttat tcatggttct
     9661 tattataaca tatctgctac taatcgttaa acgatttcca caggaaaaga attttaatca
     9721 gcctctctag aaaagaaaga gattttatga taaaatagtg agtaatatta aaaaaatagg
     9781 agagtcagat gccgttgttg agatataaaa agattatcgc tacgacctta tttatgttat
     9841 tagtgtttaa tggtattgag tatgaatgtc taaaccttgt cagtcccaaa caaacctttt
     9901 accaatccgc tgccttaatc ctctcaacca gcctactagg gatctatctg attccctttt
     9961 cactggctat tgcttatctc aagcgcatct accagataag gatctcaacc ctgctattag
    10021 ctgggctagg cggtctttat attagtggct ttttagcctc ctttggcaat caggttttag
    10081 agcaattttg gattagcctg ataaagccca atattgcctt agaggagtgg acgggagctt
    10141 tgacagggcc ttttgtggaa gagcctatta aggcctttgc agctatgctt gtcatttatt
    10201 tgctgccagc tattaatctt aagcaaaaat tagtcatcag tctcatttct ggcatgggat
    10261 tccagctgac tgaggacatt agctatattg caagtgcggc tgatcggtcc ataaatgaca
    10321 ttttgcctac aacgcttgcc aggattagca gctcaccaaa ctctcattgg gtctatactg
    10381 gtatttttac aatgggagca taccttttaa ttaaaaaatc tcaattattc ccaaggtctc
    10441 tgcagatttt ctgggtggta agtcctctag ccctacattt tatatggaac tctcctatct
    10501 cagatttagc tggtgtcgca gttattcatg gaacaataac aacccttatc tttatcagtc
    10561 tattcaaaaa aatccatgcc ctagacgaca gcatcgccta ctagcgtcat aggacacgag
    10621 caaccaagcc cagccgcatt tgggcatgtg atggctcata tgcatatata gctactcacc
    10681 tctcgcttaa gctataggca gctaaatacc tatcacaata gcagaaaaaa tgactaccag
    10741 tcttaaaagg gctagtagtc attttaagct aaaaacaagc acttcttaca ggatatacca
    10801 ctgatacaga taatagcaaa gcacaagggt catcagtatc cccatatacc atgaaaggac
    10861 aaaataccat ttcttcgttt tatggttaaa ataatgccca gctagatagg ctccaatccc
    10921 accacataag agtgacaacg ttaatagcat tttctcagaa agtcgccatt gacctttttg
    10981 ggctctgtgt ttatcactgc cataggccgc aaagaccaca gcattccaac caaaaagcaa
    11041 gattaggctt ggtagcattt gtctgtctcc aatcacagca ctacagctca cctaagatgc
    11101 tggcaatctt tgtgttgatg agatcaatag caaccacatt gctaacccct tctggaatga
    11161 caatatcagc atagcgctta cttggctcaa taaattgatg atacatcggc ttgacaacgc
    11221 ttgtgtactg ctcaataatg ctctcaaggc ttctgccacg ctcaaccata tcacgctgaa
    11281 tacgacggat aatccgaatg tcatcatctg tatcaacaaa aagcttgata tccatcagct
    11341 cacgcaaacg ctcgtcctct aataccagaa tcccctcaac aataatgacg tcctgaggct
    11401 cttggcgaaa agttctgttg ctgcgagtat gctccttata atcatagatt ggaatatcaa
    11461 caggccggcc agccaagagt tcctttagct gctgaatcat gaaatccgta tcaaaggcta
    11521 acgggtgatc ataattagtc ttaacccttt cctcaaagct gatatgtgat tgatccttgt
    11581 aatacgaatc atgctgaatc atcgcaattc tcgcatttgg aaagctattt aaaatggcac
    11641 gagacacgct agtcttacca ccaccagaac caccagtcac accaataata atgggttttt
    11701 taagcattgt aaactccaaa tctaaaagtc tttcggtcta ttttaccaaa tttgccacta
    11761 taatgctata atgaagagaa aacaaaataa aaggatagat atatgataac caaccttccc
    11821 actcaatggc aggaaaagct ggcaaagctt ggctttacta atctcacccc aatccaagag
    11881 caggtctttc agcccattgt tgatggcaaa agcctattag gcattagccc caccggaaca
    11941 ggcaaaactc tggcctattt atggccaagc cttctcaggc taagccctaa aaaagcccag
    12001 cagttgctga ttttagcacc taatactgag ctagctggac agctttttga ggttaccaag
    12061 gaatgggcag agcccttagg attaactgcg cagctcttta tttccggaag cagccaaaaa
    12121 cgccagatcg aacgcctcaa aaaaggccca gaaatcatta tcggaacacc gggacgcatt
    12181 tttgaattag taaggcttaa aaaaatcaaa atgatggcca tcaataccat cattttagat
    12241 gaatacgacg acctactgag tgactcccaa taccagtttg tccaaaaact ctcccattac
    12301 gcgcctcgtg accatcaaat gatctacatg agtgctacta acaagataga gcaagccagt
    12361 ctagcggatc ataccttggt cattgatctg tctaagcaag cattgccttg cattgagcac
    12421 tgctacatgc tggttgacaa aaggcatcgg accgatatcc tacgtaagct agcaaatatt
    12481 cctgactttc gtggtctggt cttttttaac agcctgtcag acctaggtgc tactgaagaa
    12541 cgcctgcaat atagtggagc ttctgttgct tctctagcca gtgatgtgaa tgtcaagcag
    12601 cgaaaggcca ttttagaagc ctttaaagag cagagcattt cactgctgct tgcgacggac
    12661 atagtcgctc gtgggattga tattgaccag ctagaatacg tcattaacgc tgaggttccc
    12721 cgtaataaag agcaatatac tcatagagct gggcgaaccg gtcgtatggg acgatcaggg
    12781 attgtcataa ctcttgtcag tcaccctgaa gacatcaagc gccttaaaaa atttaccaag
    12841 gtcactgaga tgtacttgaa gcatcagcaa ttataccaaa aagaaataag aggctagctc
    12901 aaaggatata aacctaaaaa gcttgcctcc aagtatgatg taaagcaact aatcactatt
    12961 tcttaccctt gctactaaaa aaacgaacgt aaagtccttc tgacatgaag tcaaaacctt
    13021 acgttcgttt tatattatac tgacaccact ggctttatta gtatagtaga tactggccat
    13081 gcttagccag actagatact ttcttgaagt gagcccgcca tttagtcatg ctctagagcc
    13141 ttacttgctt tttctgactg actagcggct accatatagc tcagataagg tcacacattt
    13201 gtatccttcc gcttttaggt attccataat acttggcaag gcatctacac tggtctggtg
    13261 aatatcgtgc attagaacaa cccctccagg ctgcaattgc tgcttgacat ttgccatgat
    13321 agcagcagta ttacgatttt cccaatctct ggtatcaact gtccaaagca tttccttaag
    13381 acccgatgcc cttctaacaa tatcattagt agctccataa ggaggacgaa gatagactgg
    13441 gcgttttcca caggcctttt cgatggcttg attggtcgta ttgatctgtg tttggatctg
    13501 atcaacggtt agggtcgtca aatcagggtg atcccaagaa tgattctcaa catcatgacc
    13561 agcagcacta accttcttaa ccaaagcctc atggccaaca accttagacc ccatcataaa
    13621 aaaggtcccc ttggcctgat atttggccaa aatatctaaa acctgcggtg tggtcacagg
    13681 gtctggacca tcatcaaagg tcagagcgac tagcttttgt ccctcttttt ctgcctcttt
    13741 tgccttcttt tcctccaaat actcttcata agcagtcttg tctgaaccct ctagaaaatc
    13801 tggattaatc acatcaaaca ggcttgcaag aggtattgac atatgaccaa ataaaataag
    13861 attacccgaa tcaatggcaa agccatcgct taatacctga tttttttcta tcatcgtatc
    13921 agtgctcagc ttgatctctt tgcctggata aagcttgcca acctcttcct cgatgcgatc
    13981 taagcgacca gcaactagct cctctagctt aaaggggcta taatcctctt tcacatggta
    14041 acgactaaca gccttttctg tagtcttttt tagaccaaat aactgaggct tgtagaccgt
    14101 cttgtagata accaattgat tgacctgctt gatatgtgaa gcctcaagct taggctttac
    14161 catgataaca gccttgtcag tctgcttgcc ttgatacaga gacataggca gatttgacac
    14221 ataaaaatcg tcagccttct caatcggaga caggtaatac caatcctgct ttcctttctt
    14281 gagatacttg acctttttga tctttggact atccttagaa gcagtctgtt cgagcttaat
    14341 gactctctga gtatcctgcc ctattttcca agatctaatg aaggtaaacg caacaccgac
    14401 caacaataaa cttaataaaa taatgagaat ataatttagc tttttcaatc tcgtcctcca
    14461 attaccctac aattttaaca caagatagtt ggaaaataaa taaaaaaagt taggtttcct
    14521 taactttttt cagtccaaaa taagggcaaa aaagtgtttt atggtgcagg atttgcctga
    14581 gttattttcc ctttatcaca gccatttgtc actggataag gggctagata ttatacctaa
    14641 agcttctctt tattgctatc attattctga cattcttagg catgctattt cccttgatag
    14701 gacttgattg ctgtttcttt agcttgtaag gatctcctaa aaatgagagt atttttaagc
    14761 ctataattta tatattcgaa aaattttgac aaaaatgagg aaaaatattg atttatttag
    14821 ctttagtgat aaaatgaggg tgaaaaatta aataaaggag gacattgata tgtctcagaa
    14881 gttgggaaaa caacttattc gctctgttgt tactgcctta gccgccatag catttggaat
    14941 atttcctgca agcgagacga ctaatcatat cacctatgca gaggttaact ccttaacccc
    15001 ttcggtagaa tggcctttag agcagtatcc taattactat agcatagaag gaaagtctaa
    15061 tatcaacacc aaggattttc ctaagctata caccactacc gaaaaggttt acaaaaaaag
    15121 tggtcgaagc actaagcgcg ttactgtttc tgatctgcaa tacgctgcac ttgatggcta
    15181 tggccgttca ggagctgcct atggtattat cacaaaggat atgatcgcga tgtcagccgg
    15241 ataccgcgaa aaatgggaaa gcaatcctga gccaagcggc tggtatacat atcatttcaa
    15301 agaaactggc aagctagcta ctgaggccga ctaccttcac agcaaaagca agatcaaacg
    15361 aacctcaaac aatagctatg aaagcatcgt ccttagcaac ggtaagattc gcaacggcta
    15421 tctttttgat cgtagtcatt taattgctga cagcttaggt ggtcgtcctt ttagaaataa
    15481 tctcatcaca ggtacacgta ctcaaaacgt tggcaacaac gaccgcaagg ggggtatgca
    15541 gtacattgaa aacaaagtcc taaactatat taaccacaac cctcaggttc acgtttatta
    15601 caaagccgta ccaatctact caggctctga attactccct agggccgttg tggtttcagc
    15661 gctctcctct gatggtaaaa ttgatgaaac cgtaagagtc tttaacactg tcaatggctt
    15721 taccatcaat taccaatata gcggcatcag ccatgataag ggcatggagg cttctagtga
    15781 gtcagaagct gaggatatta cagacgaaag cactccagta gctgaaccag ctgatgagga
    15841 ggctatggag acagaggctg ctgctaacga cacaatagtc tatgttacaa gtaatggcca
    15901 atcaaaggta tactggtata ataaggacca tctgccagag aaggtcaatc tcaataaggt
    15961 tgtagaaatg accgagcagg aagccctaaa tcgaggaaag caccattcct ccttagaaaa
    16021 aataaatcaa tagtctcata acgactaaca caagagctgg ttgaagcaac cagctttttt
    16081 tgtgtgatga aggattagac agctccttag ctaaaagata aagaggctga taaagcactc
    16141 aacctcttat cgcttttata aatgctctgg tactgcggct aatagctctg atagcttgct
    16201 tgcatcacta ccacctgcca tcgccatatc tggcttaccg ccaccacgac ccgacacgat
    16261 tggcgctaag gccttaatca gattgccagc gtgagctctt ttatccttac ttgcaacaag
    16321 aacattgacc ttctcaccaa tgcttgcagc cagcacaagg acatctgaat aatctctttg
    16381 cttccaatta tcagcaaagg tacgcaagac tcctgcatct gatacggata cctcactagc
    16441 aatgtaacgt agaccgtttg cttcctggac ctttttaaag acatcaccag cctgagctgc
    16501 tgctgctttt tcttttagct ctgccatttc tttttgcaaa tcgcggagct gctcgctgag
    16561 gctcacaacc ttacttggaa gctgttctat ttgcggcacc ttaagcgtat gtgcaatttc
    16621 ttttaggatg tcttcttgct tgcggaagct ttcaaaggcc tgctgacctg tcactgctat
    16681 gatacgacgt gttcctgagc cgatcccctc ttccttgata atcttgaaaa gaccaatttc
    16741 tgatgagttg gacaagtgag tccctccaca aagctcaaca gaataatcgc caatctgaac
    16801 aacacgaaca gttttgccat atttttcacc aaagagggcc atagctccca tagcctttgc
    16861 tgtttcaata tcagtttctg tggttgtaat agctaatgcc ttccagattt gctcattgac
    16921 ctcttcttca atacgacgca gctcctgggc tgtaacggct tcaaagtgtg taaagtcaaa
    16981 gcgtaaaaag gcttcttcat ttaaggaacc tgcctgagtg gcatgttctc caataacctt
    17041 gtgaagggca gcatgaagca gatgagtagc ggtatggttt ttctcaacag catagcggcg
    17101 cttgtgatca atagcaagag tataaacagt gtctaatgca aggcttgcaa gaacctcaac
    17161 agtgtgaaga ggctgaccat tcggtgcttt ttgcacatct atcacacgag caacaaggtc
    17221 acccttatca tttttgataa ccccatgatc ggcaacctga ccacccattt cagcataaaa
    17281 cggtgtctga tcaaacacaa gcaaggcctg tccttctgaa accatctcac tacgctcatt
    17341 atcaacgatg ataactgata agcgagaggc aacagtctct gtttcgtaca aaaattctga
    17401 tggctctgtg atgcctgcca gtgtctcatt ttgcatgccc attgagccac ccttaacagc
    17461 tgctgcacgg gcacgatcct gctgctcctt catagctgcc ttgaagcctt catgatcaat
    17521 cttatagcca gcatcttctg ctaattcttc ggtcaattca actggaaagc cataggtatc
    17581 atacagctta aagatatcct tgccatcaag cctgtcttgc cccttttcct ttagctgcgc
    17641 cagcaattga tccaaatgcc ctgatcctgc atcaatggta cgtgcaaagg tttcctcctc
    17701 acgcttgata attttttcaa taaagtcacg cttctcaaga atctctggat aataggactc
    17761 catgatatga cctacagtag ctactagctt ataaaggaag gtctcatgaa taccgagcct
    17821 acgaccatgc ataacagcac gacgaagcaa gcgacgaagc acatagccac gaccttcatt
    17881 accaggtagg gcaccatctc caatcgcaaa tgacaaggca cgaatgtggt ctgcaatgac
    17941 cttaaagctc atgttgtcac catcttggtc gtaagtatgg ccagatagct tttccacttc
    18001 cttgatgatc ggcataaata ggtcggtttc aaagtttgtt tttgcgccct gcataacagc
    18061 cacaagacgc tctaagccag cacccgtatc aatgtttttg tttggaagct ccttgtactc
    18121 tgagcgagga attgtagggt ctgcgttaaa ttgagacaaa acaatattcc aaatttcaat
    18181 ataacggtcg ttttcaatgt cctcttccag caatctaatc ccaatatgat caggatcata
    18241 agcctcacca cgatcaaaga aaatctctgt atcaggtcct gacgggcctg caccaatctc
    18301 ccaaaaattt tcctctaatg gaatcaaatg gcttggctca acgcccagag caatccaacg
    18361 attgtaagag tccttgtcat ctgggtagta ggtcatgtat aatttttcct ttggaaaatc
    18421 gaaccattcc ggacttgtta acaattcaaa gccccactca atcgcttcgt cgcgaaaata
    18481 atctccgata gaaaaattac caagcatttc aaacatagta tggtgacgag ctgtcttacc
    18541 aacattttca atatcgttag tgcggattga cttttgagcg ttggtaatac gaggattttc
    18601 aggaatgact gacccatcaa aatatttttt gagggtggcc acaccagagt taatccaaag
    18661 cagggttggg tcattgactg gcacaagatt ggccgaaggc tcaatagagt gaccttttga
    18721 tttccaaaaa tcaagccaca tttggcggat ttgggctgat gttaactgtt tcatgattaa
    18781 gataccaaga gcgattagag agactgggta tgattgtcct tagcataagt agcctgggga
    18841 gacgatctct actcgcattc agttcctttc gttgattttt tatgggatta ggctaaaagc
    18901 catcaaaaca aaacaagccc atatcacaga gggcgaaaac cgcggtacca cctctattca
    18961 atgagcttgt cattcttaat tacttatatc agataaaatc acattaagca gcatgcctat
    19021 cagattatcc gtaactcaca gcaaccgtca cttctctggg tcaaatcctt gataaacaat
    19081 tcttaactaa accagtataa agcttttttg agcattcgtc aatgaaaatc tatttttctg
    19141 acttagattt agaagattga ctatccttgc ttgagtctga agatgatttc tgatctgact
    19201 tgcttgtgtt cgccttgctt gcttttttat cagtattggc atactgtgcc aagatattag
    19261 caaatgcttg gtctttgatc ttaacatttg ccttgtctaa ggcctttgca atgaccttat
    19321 tttggaaatc aatgttttgt gtcttttcag ccaagacaat ttcttttaga cgtttcttat
    19381 atttcttcca atcagaagcc ttttcggctt ttttggttac cttaacaata tagaacttgt
    19441 tttgataagt agccggatct aagacagaaa ccacctctga aatatcaccc tcttttaatc
    19501 ctgaggcggc cttgatcaca tctgctggta acttagtgtc tcctgagtca aacttatagt
    19561 ctaccttctt gtctgctgct gttgtctttt ccttagcaat agcagcaaag tcagcaccct
    19621 cagccttaac ctcacctaaa acagcctttg ctgtttcttc attgtctaga gtagtgacct
    19681 gagtagtcat ttctggtgtg tatgactcat aggctttttt gtaatcagca tctgtcagct
    19741 cttttttagc tgcttcttta acagcatatt caaccagcat ggctgagcga atttgacgct
    19801 tgtaggtatc tgttgtcaag ccagactgcg caagggctgc agagaatgac gcaccgtatt
    19861 gctcagctga tttattgtaa gcttcttccg ttcttttctt agaaaccttt ttaccgtatt
    19921 ggtcctcaaa aacacgacta accacaaggt ttagcattgc tctttgagaa atctctgtat
    19981 tttttgtttc attgtaaaaa tcactaacac tgatagtgtc gcccttcatc gtaatgacac
    20041 ttgtattgtc atttgtagac tgacaggctg ctagggtcat tgctgatgct agggttacga
    20101 taccagcaag taatttagtt gattttttca tgtgattttg tgctcctttt tgtcattaac
    20161 cagtatatta tatcacaatt tcttaaacgt aacttaatct aacaaacgaa tatctgcttg
    20221 atttttacga atcatcagca agccatcact aagcggcagc aggctggctg tcaatccagg
    20281 attatcaaga gttgctgcaa ataagtcctg aaggccacga taaatcgtgc gctgtcctct
    20341 ccgaacctcc ttgatcggct tagcaatgtc acccccctga aacacatcat ctaaaacaac
    20401 cattccacct atttttaagt gctttaacac ctctggaaga aactgaatgt attttgattt
    20461 tgcagagtcc ataaaaacaa agtcaaactc gccagtaagt cctgctaaaa gatcagccgc
    20521 atctccttca agaagggtaa tttgcttgcg gctatcgtat tttgcaaaat tttccttggc
    20581 aaagccaatc atctcagcat tgcgatcaat cgttataatc tctgcctcag gagcattttc
    20641 tgccattagc aaggcagaaa agccaatagc tgtgccaatt tctaaaatcc ttttgggctg
    20701 caagctttgc aataaaagcc tgaaataagc aacaacctca tgctggataa tgggaatatt
    20761 ttcttgtctg gcaaaggcct caagctctgc taaaaagcct tcgttttgct ttagctgcgt
    20821 tcgcatgtag tgaacaatgt cttctttgac aatagagcgg cgcatattat gatttgcatt
    20881 tttactatat gatttaacca tgctatccat tatataaaaa aactctaggt aatgctaggg
    20941 ctttcactag cctattcacc tttgacgatc tgagtagtat ctatcaaagg agctcacaga
    21001 cagccttaag ctgcttgaca atgctatcac aagcagacaa gtcctgtaag ggataatcag
    21061 gattggcaaa gccgatacag gtcatctgag cagccttagc agcctgacta ccatgcttac
    21121 tatcctcaat gacaaggcag gtcttgggat caacgcttaa ccattcagca gccttaagaa
    21181 aaatatctgg cgctggcttt gagcgagcaa cctcttcacc actaactaac acctcaaagc
    21241 agtccaaaag acctagtgca gtgagatttc taataatatc tgccttaggc gatgaggaag
    21301 ctactgccaa gcgatagccc ttcgcatgca ggtgcttgat taattgagca gcacctgcta
    21361 tggccttgac accgtcacgc tcaagcattg cttgacgacg atgattcatc tcagcgatga
    21421 gggcttcaac agaatcctct agctgacact cctttttcat agttgtccac atatcgtcaa
    21481 aggtggttcc cataaactgg tactgatacg cttcattggt atctatgcct cggtccaata
    21541 gcatttgtgt cttggttgac aaaaagatat attctgagtc aacaatcaca ccgtccatat
    21601 caaaaataag gcttgttttc atcatctacc tcctcttatg ctatatctca gtcaggtcaa
    21661 gagcaagact attaattact agagctattt ttaccagaaa aaagctcaac aatatctgac
    21721 agctgactaa tatgatgatt atcatcacta tctggcagca ataggttgat agagctaatc
    21781 ccagctgccc ttgctgcagc aaggtctaag ggcctatcac caatatagta ggtctgcgac
    21841 ttatccatct gataatgatg aatgagaaaa agaagcgctt cagggtccgg cttacgctta
    21901 aagccacaat ctgctgtaat cacctctgta aagtaatcag caatccccag acgctgcaaa
    21961 acagcctgag tggttcgtcc tttatgagtc acaataaaag gcttaacccc ctgctgagag
    22021 gttaaggcta atgtttcctt ggctgtaggc attagtgcta ttaggtgatc acgcgcttcc
    22081 tgctctcggg taaagaaggc cagcaattct gaaaaatcca gctgatgtgc ctctgctaac
    22141 ctcttcaaaa gctgtccgat ggattcttga ataatcgtat ccataaccca agcctcatca
    22201 aagggcagct gataggtctg atacaataaa cctagcgcct gacgaatagc ctcagaggat
    22261 tggactagag ttccatcaaa gtcccaaatg agattaactg tcacaatcct tacctcttaa
    22321 atcaatccaa taacgagcaa tagcctgccc tgctaagctt gtagtagggt aatcatctgc
    22381 cacctgaaca atatcctcta aaataccacc agccttttca atggtttttc gactggctat
    22441 attatcttta ttagctgtta ttaagacacg cttgatccca cgctcttgat attgctgtaa
    22501 tgcaaaggcc agcaagtctg tcataattcc acgcccgcga taatctgtcc ttgtcacata
    22561 gccaatatgt ccgccaattg ttgctaagtc tcctttttcc aactgccagc gacagcctat
    22621 tctagccact agctgaccat ctaaaaaata gtaataatta gtgctagtgg accagtcagg
    22681 atgatcagtt tggacctcaa accgtctaga ttgctcaaca aaggctgcaa agtcctctac
    22741 ttttttggtc tcaacaaagg tattacctga agctttttca gctaacagta tatcctgaaa
    22801 gcgcttaaag gctgcttgat cagctaaagc aattgttcta atctctttca tgcctggctc
    22861 ctttttatta tgctaaaaat caactgggca tttctcaagc attcatcatg ccaacgaaaa
    22921 agagctgccc ctagaactgt tgatgtaata ctacgtctag aggctgccca caggccttta
    22981 agctaggctg atagacactg actgctgcta tttaccaata gctcaaaacc taagaggaga
    23041 tggcaactat tagagatgtg cccctcttgc cactaagtcc tctagctctg tcaaacgctc
    23101 ttcaaagacc ctaaaggctg cttctaggta atcaccctta gccatatcaa caccagcctt
    23161 ggcaatcacc tcaagcggat aatctgaatt tccagacttc agataggtca agtagtgatc
    23221 aatatcctct tgagtaccat gcacgatctt atcagccaag tagctggctg cagcaaagcc
    23281 tgttgcatat tgatagacat agtagttgta atagaaatgc ggaatgcgag cccactcata
    23341 ctggataaaa tggttgtcct ctttttttaa gccataatat ttttcgttta aatcagcata
    23401 gagattattg aggtattcac ttgttaacac ctcgccattt tgatccgcct gatgaatagc
    23461 gtgctcaaac tcagcaaact gtgtttgacg aaaaaccgtt ccacgaaaac catctaggta
    23521 atgattcaaa atagcaaagc gctccttatc atcctgcacc tcatgtaaca aggcctcagt
    23581 catgatattt tcattagtgg ttgaagcaat ctcagctaag aaaatgctgt aatctccata
    23641 cacgtaaggc tgtgtttcac gcgtaaaggt tgagtgcagg ctatggcctg tctcatgcac
    23701 tagcgtatag aggttatcaa gcgtgtcctg ccaatttaag agcataaagg cattggtatc
    23761 ataggaacca ccagagtaag ctcctgagcg tttgccctta ttgacatgca catcaatcca
    23821 acgctctgta aaggcacgat gcacacgctc tgaataatcc tggccaaaaa cagccaaaac
    23881 cttctctgct ttttccaagg cctcatcata gccgatagca agatctgtct cagataaagg
    23941 agtataaaca tcatacatct ttagatcatc taaaccaagc acctcttgac gtagcttcaa
    24001 ataacgatga agcagcggca aatgcttatt aacgttttct agtagggtat cgtaaacagc
    24061 ctctgggata aagttggctg acatcgctgc ctgacgggct gaagcatatt tgtgaacacg
    24121 tgccttataa ttttgcacct ttacattggt ttgcagggtt ttagcatagg tgtgctggaa
    24181 ttgctcataa gtactataca tggcttcata ggcagcccta cgcaccttgc ggtctttcga
    24241 ttccatcaag ctaatgaaat taccatgtgt tagctcaacc tcttctccct tatcatttgt
    24301 cacaatagga aaagcaatgt cggcattatc taggatacta aaggtctcct cagcaccatt
    24361 aaagatttct tgtgcccctg ctaatagctc ctcctcagcc tgactaagga catgctcacg
    24421 cgtcttgaac aatttatcaa agaaatggtc atagactgtt agctccggtg tctcagctaa
    24481 gaaggcttgg taggcttcct gacttaaggc cataaattct ggctcataga atgaaaaggc
    24541 ttcactaaat ttagcataaa taccagaggc cttagcttga tattcttgat acttggcaac
    24601 tgtcgtatcc tgatcatttt tcatgctagc ataaacataa accttttcaa cacgacgagc
    24661 cagctccaaa tgcagctctg tgatatctaa gagactgctg cttgaatcca acaaatgccc
    24721 agcctgctgc cttgcagcct caattgctgc cagcagacta tctgcctctg tctcccaagc
    24781 tgcgtctgtt gcaaaaatag tgcttaaatc ccaagtgtac ttttcctcta gatgactacg
    24841 attatctgtc atacggacct cctaagtttc tattactaat cattttaaca taatatgctg
    24901 gtgaaaaaag cttttgcacc tctttatttg ctgcttttgc gtaatatttt tcaaagcaat
    24961 cgtaatagtg gctcaaatcc tcatgaatct ggcaaaagcc agctgagcaa gcaatcggct
    25021 taacctgtgg ataataagcc tctaggggcc tatcaagcag gttatcccca gctagataag
    25081 cctcttcttg ctttttcaac catttgctat cttttgctag taaggctttt tgaatccttc
    25141 tcagcaagtg cttatccatc tggagctgat aggctgacag gccttttctt tggtaaggca
    25201 gccgcaaaaa ggccaacaaa tcatcatcta aggaacaggt ctttactaga tagctgacct
    25261 taccaaataa atcctcatga atcata
//
LOCUS       DARYLD010000031        25146 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYLD010000031 DARYLD010000000
VERSION     DARYLD010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25146
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..975)
                     /locus_tag="TU651_001120"
     CDS             complement(<1..975)
                     /locus_tag="TU651_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL0897129.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHS"
     gene            complement(975..1706)
                     /gene="trmD"
                     /locus_tag="TU651_001121"
     CDS             complement(975..1706)
                     /gene="trmD"
                     /locus_tag="TU651_001121"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL0897130.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(1696..2214)
                     /gene="rimM"
                     /locus_tag="TU651_001122"
     CDS             complement(1696..2214)
                     /gene="rimM"
                     /locus_tag="TU651_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL0897131.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(3489..3728)
                     /locus_tag="TU651_001123"
     CDS             complement(3489..3728)
                     /locus_tag="TU651_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL0897132.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(3738..4010)
                     /gene="rpsP"
                     /locus_tag="TU651_001124"
     CDS             complement(3738..4010)
                     /gene="rpsP"
                     /locus_tag="TU651_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL0897133.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(4441..5058)
                     /locus_tag="TU651_001125"
     CDS             complement(4441..5058)
                     /locus_tag="TU651_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0897134.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(5051..6274)
                     /locus_tag="TU651_001126"
     CDS             complement(5051..6274)
                     /locus_tag="TU651_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897135.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(6286..6996)
                     /locus_tag="TU651_001127"
     CDS             complement(6286..6996)
                     /locus_tag="TU651_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897136.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(6996..8258)
                     /locus_tag="TU651_001128"
     CDS             complement(6996..8258)
                     /locus_tag="TU651_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL0897137.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(8573..11749)
                     /gene="carB"
                     /locus_tag="TU651_001129"
     CDS             complement(8573..11749)
                     /gene="carB"
                     /locus_tag="TU651_001129"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL0897138.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(12167..13258)
                     /gene="carA"
                     /locus_tag="TU651_001130"
     CDS             complement(12167..13258)
                     /gene="carA"
                     /locus_tag="TU651_001130"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL0897139.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(13281..14216)
                     /locus_tag="TU651_001131"
     CDS             complement(13281..14216)
                     /locus_tag="TU651_001131"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL0897140.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(14274..15533)
                     /locus_tag="TU651_001132"
     CDS             complement(14274..15533)
                     /locus_tag="TU651_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL0897141.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(15549..16070)
                     /gene="pyrR"
                     /locus_tag="TU651_001133"
     CDS             complement(15549..16070)
                     /gene="pyrR"
                     /locus_tag="TU651_001133"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL0897142.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            16432..17046
                     /locus_tag="TU651_001134"
     CDS             16432..17046
                     /locus_tag="TU651_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0897143.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(17127..18017)
                     /locus_tag="TU651_001135"
     CDS             complement(17127..18017)
                     /locus_tag="TU651_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0897144.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(18007..18465)
                     /locus_tag="TU651_001136"
     CDS             complement(18007..18465)
                     /locus_tag="TU651_001136"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL0897145.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(18693..19622)
                     /locus_tag="TU651_001137"
     CDS             complement(18693..19622)
                     /locus_tag="TU651_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL0897146.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(20029..20322)
                     /gene="rpmA"
                     /locus_tag="TU651_001138"
     CDS             complement(20029..20322)
                     /gene="rpmA"
                     /locus_tag="TU651_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL0897147.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(20344..20676)
                     /locus_tag="TU651_001139"
     CDS             complement(20344..20676)
                     /locus_tag="TU651_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL0897148.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(20689..21003)
                     /gene="rplU"
                     /locus_tag="TU651_001140"
     CDS             complement(20689..21003)
                     /gene="rplU"
                     /locus_tag="TU651_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL0897149.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(21037..21111)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(21233..22426)
                     /locus_tag="TU651_001141"
     CDS             complement(21233..22426)
                     /locus_tag="TU651_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL0897150.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            22691..23308
                     /locus_tag="TU651_001142"
     CDS             22691..23308
                     /locus_tag="TU651_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL0897151.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(23606..24835)
                     /locus_tag="TU651_001143"
     CDS             complement(23606..24835)
                     /locus_tag="TU651_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0897152.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
BASE COUNT         7566 a         5830 c         4461 g         7289 t
ORIGIN      
        1 tgaatgaaca ggtctattat ctctatcagg ataaatatac ttaatcgctt ggttgacagc
       61 aatcggtgcc tcaccaaagc cagtggcaat caaatcaacc ctgccttcat aagctgctgc
      121 gtcaccgatc gcaaaaatcc cttcctgact tgtttgaaag aggggagaga caagaagact
      181 tgagcgctta taatctagat tccaatgctt taggttttta ttagatgtag aaaagccaaa
      241 gctaacaatc aggctgtcta gctcaagcgt tatctcctct tctgacttta ccttttgaat
      301 agtcattttg ttgacaaagc cattttctcc ttcgagggca aggggaacaa agggggtaag
      361 ggtagtaaca tgagagtttt ttaacaattc tacgctatgc tcatgagccc taaaggcgtc
      421 tcgccggtgc acaagggtaa cactcttagc gaggccatct aaggctaaag cccagtccac
      481 agcagaatct ccaccaccgc agatcacaac cctcttacca gcaaactgat tcaagctgtg
      541 aacattataa aagagattat gatcagcaaa taactgctca ttgtctaagc ccaaggttct
      601 aggcgcaaag gctccattgc cacaagcaac aataatggcc ttagaataat gtctggcctt
      661 gcttgtttga ataacaaagt tcccatcagc cttctcaaaa gacaggacct cttctttcag
      721 gcatactgct atgcgatcgt caaatctgct tagctgctca ataagctttt gtgttagttc
      781 cgctccagtc agggccggat aagctggaat atcatagata accttttcag gataaagaac
      841 agccggctgt cctcctagct ctgacaggct ttcaataatc ttaaccgtca tgccgcgcag
      901 gcctgcataa aaggctgcaa ataagcctac cggacctcca ccaatgatgg taatgtcata
      961 tattttttct tgcactagtt ctctccttca cttagccccg atttgatttt atcaaaaatc
     1021 cttttttcct catcagaaaa atcataagtc tctaataaat ctggtcttct caaataggtc
     1081 ttctttaggc tttgctccat acgccagaga cgaatatgct catgatggcc actcattagg
     1141 acatcaggca ccttcatgcc acgataatca tatggccttg tatactgtgg gtactccaag
     1201 agcccagatg agaaggaatc ctcttgatga ctggcttgct ttccaagcac attaggaatc
     1261 agtctcactg ttgcatcaat cattgtcata gcagccagct caccaccagt taagacaaaa
     1321 tctcccagag atatttcatc ggtaacaagt gtcttaatgc gttcgtcata gccttcgtaa
     1381 tgcccacaaa taaaaattaa ctcttcctca agagctaatt cttcagcata agactgatga
     1441 aagggttttc cagcaggatc cagtaaaatc actcgaggct ttgtagcctg aatgctatcc
     1501 atggtatcaa aaataggctg cgctctcagc agcatgccct gcccaccacc atatggctca
     1561 tcatcaacat gcctagcttt ctccgcatgg tcacgaaaat tgtggtaatg aatatctaaa
     1621 agcccctttt ccttagcctt tccaacaatg gagtgctcca aaggagcaaa catttccggg
     1681 aaaagggtta aaatatcaat cttcatcatc taagccttcc ataatttcaa cgtctacccg
     1741 atgcttttcg atatcaacac aaagaacaac cgatgggata taaggaagca acaggtcacg
     1801 cttgctttgc cgtttgacca cccaaacatc atttgcacca ggctgtaaaa tttccttaat
     1861 ctctcctact agctggtcct tttcatacac ctccagacca ataatctggt gatagtaaaa
     1921 ttctccctca gctagcttac cctgattctc tttagcaatc ttaagactgt agcccttaaa
     1981 ttgctcaata gcattgatgt gatacattcc cttaaacttg ataatgtcaa actgcttatg
     2041 cttgcgatga ctcgcaatct caacctcctg cacaaaacga tccttgtcgt caaacagggc
     2101 tagtctagca cctttttgaa atcgttcctc agtaaagtca ctcacagaca gcacgcgcat
     2161 ttctccttgc aagccttgag tattgacaat cttcccaacg ctaaaatatt ccatccttac
     2221 tcctaatcat cttagactct atagcttgat agacctctat tttttcatga caacacgaca
     2281 tgagtatcat catcctaagc actctagcct atcgttaaag ctccccttat tgtaacatgt
     2341 tctgccttat tttgcacttc tctttcaaaa aattaatctc ccagttatag cagctaagcc
     2401 tagcaagcaa agcccttgat gctaaagaat cctgatcccc ctataattaa caaatcatca
     2461 tgacttgcct tgcccaagct cagtcaagtg aatgaaaaat ctgctaaaca atagccttgc
     2521 gcctcgctga caagcatcaa aaaaacactc ctgctggcaa tctgaactgc cccccaattg
     2581 ttagatttta tgtccaactt ttgggggtca gtacaatcta gtaaactaga atcaggagtg
     2641 tttcattata gcccaacaag caaaaggaat acttggtaaa agcaaagctg acttgcattg
     2701 agaagattaa aaccattcaa tctgtcacaa taattatgga aacattggga atttaaaaac
     2761 aagtatcagc tgctatcaac ctgtggggaa atagtctacc tatgcctatc gggccatcca
     2821 tcataggtcc tctcaagaaa tgatgagagc ctcatcaacc agctatcatc gccttaaagg
     2881 agaatgacga atgttatcgt aggtgtccca agaaatacta caaaagaaac tcattttgat
     2941 cttaatgctc taaagggctt gaccttacgt caactgataa agctctactt catagcatcg
     3001 ttttgctttg cagcttttct atacctcatg tctaataaaa gacataagct tgccgataag
     3061 aacattaccc caacatagaa gaatagattg gtctcatcgc cagtctttag taagatggta
     3121 ttttgatgct tcatcggttt ggtagctgtt gaaacatgcg gacacttggt ttcatttgtc
     3181 gtcgatggta ttgtcggacg acttggctta gtgttattag gcttatgatt gccttcacta
     3241 ctgcttacct ttttcttcca ctgtgcaaac aattcattag gaaacggcag gtcattatct
     3301 accctaatgt catcacctac cttttttaac ctcctgctcg atctcttgtt gcatacaaaa
     3361 tgttatacag atacttctgt cagatagagt tcttgctttt gtctcttgac ttggtgattc
     3421 aaaacacaaa aaaagcctgc tagatagaac tagcaaggct ttaagattag tcttgttcaa
     3481 aatagaactt atttttcatc aatgactaat cgaacctttt ttcctaaagt tggcaccgaa
     3541 tagacaatcg atcttatcgc tgtgatggta cgacctttct ttccgataac acgaccgatg
     3601 tcttgagcat ccaagtcaag atggtactct aaaaaatccg gagtatcttc aattttaata
     3661 gtaagcttat ctggttgtga aatcaagggc ttcacaatag cgataatgag attttcaatg
     3721 gtatccatag gcttttatta cttagaaaat ttttgatcgt ggaatttagc cataacccca
     3781 gctttagata gaaggctacg aactgtatca gaaggttgtg caccttttcc tagccaatca
     3841 agaacacgat cttctttaag agttacttga ttttcagcta caagtgggtt gtaggttcca
     3901 actgtttcga tgaaacgacc atcacgtggt gcacgtgaat ctgcaacgtt gatacggtag
     3961 aaaggttttt tcttagaacc catacgagtt aaacggattt ttactgccat tttaatatgt
     4021 ctcttttctt taaatgataa tagtcaagaa atgtagtcct gctcatttct cacctaacta
     4081 gtatacttta cttttgatta tgtgtcaagt ttttttcttg acactttttt atgatcataa
     4141 tactactcaa catcttcaat cagctaagct gcttagatga catcaaacag caggcagctg
     4201 ctcttataag agcatacaac tccaaactaa cctactctag tgatccttag ccgtcaataa
     4261 tgggatcagg caagcataac tccccgtcaa aggagcggtt tgtttcacag caaaaaggcg
     4321 aaataaactg acaatcacat caaaaaggac gagcccctaa acatgcagga gctcgtcctt
     4381 ttaccaatat gacttagtct ctccttgctt ttaaggctag ggtattagct aagcgttaca
     4441 ctaataatgc atcaaaatat gcttaagaaa ctctccacca taaatccaaa aataactgaa
     4501 ggtcaaaatt gaaatgggtc tacaaattag gataatcagt aaaaagcgct tgtaggtcat
     4561 ctgactcaat ccagtaatca taataagagc atcggcaggg gctaaggggg aaatcatatt
     4621 gagaataaag aaacgctcaa ataatttcgt tgatagcttc ttttcataaa actgtagctg
     4681 ctccatactt aaaaacagta agataaaggg ctttccgtat ctcctcacca actgaaacaa
     4741 aatagaagat ccaatgcaga taccaaacac atttaacata aagcctaata taggaccaaa
     4801 ggctagaaag ccaacgactg ttgtcacacc accaggaatg ataggaacaa ctacctgcac
     4861 aatttgcaag ataaaaaagc aaatggcacc gataaggaga tgatccttga ttaaatgggc
     4921 taaagccttt ggattattaa taatatctag ctgcctaata aggtagacaa caagcatgac
     4981 ggagaacaga attgataggc caccaagaat cttaaacagc ttctttaaca acgaatgtga
     5041 aacaccaaag ctactcatag cgcaaagcct ctatcggatc aagcttgctt gctttgtttg
     5101 ctggcagcaa tccaaaaata ataccaattg atgccgaaaa gataatagct acagccgcaa
     5161 catctaagga aacagctgct ccctttaatt gcatcgcatt tcctagcaca cctacacaca
     5221 tctgtgctag cagcagccct aaaagaccgc caattaacgt caacaccact gattcaatca
     5281 aaaattggct aagtatcttc aagcgcgttg ctcccaaggc ttttcgcaag ccaatttcac
     5341 gtgtacgctc tgttacagat accagcatga tgttcataac accaatacca cccacaagaa
     5401 gggaaattcc tgcaatggac ccaacaactg tggtcatgat actaaattgt gcgttaatgt
     5461 cattgataat ttggctattg tcaggaacag cgtactcgcc ctccttaaca tgagacagtg
     5521 tggtcagcat agcagctgct tgatttccta attcaaggct tcgcttaacg tcgccaatat
     5581 aaagataaac agagccaatt tccttgacat gaaattctga agccacctgg gtattggcca
     5641 taatggctcc tccagaaatc ccaccagcaa acgaaacaac ctcctgatca gtcttgtaaa
     5701 cacctactac aaggtagtcc ttactatcta gactaaccac cttatttaga gcttgttcat
     5761 aattgccttt gccaaataat tcgtcagcca agacagtatc taataggata atgcgagaaa
     5821 aatttttata atccttgcta tttagcgtcc tacctgcaac aatatcatat tttttgactt
     5881 taaaataatc ctgactaacc ccagtgatgg ccacattgtc catcttcttt ttctcaaagg
     5941 aaatggtaga ggttgaatta ttggtatagt aataagaatc taccccatca attgctttga
     6001 caatctgctc tagccattca ggcttgacct cttgctcatt ttcatgcgct gcaaaggccg
     6061 cgtaagggtt gtcctcatct ccttttgcct tgaaataaag ctgaacctct ttttggtcat
     6121 ttgaaaagga atccgtaacc ctctttgtca tggcagcacc aagccccatg ataatcacaa
     6181 cagcagctac accgataata attcccagca tggtaagaat cgaacgcagc ttgtgccccc
     6241 agattgaact aagagcaaat ttccaatttt ccatcacttt tcctcctagt caatcctgac
     6301 actttctgtt gtatcagctg tgatttcacc atcacgaata acaatttttc gagtggcaaa
     6361 gtccgcaatc tctggctcat gagtaaccat aataatagtt ttgccttcct tattcagctc
     6421 cgtcaaaagc ctcataatct gctcaccagt ctttgtatct agggcaccag tcggctcatc
     6481 agctaagata atagacgggt tattaaccaa ggctcttgca atggcaaccc tttgcttttg
     6541 accacctgat aactctgatg gcaaatgctt cattcgcata ccaagctcaa ccttttccaa
     6601 aaattgctta gccaattcac gacgctttga tactccaact ccagcataaa tcaagggaag
     6661 ctcaacattt tgcagggcat ttagctttgc tagtaaaaag aactgctgaa agacaaagcc
     6721 aatctcttcg tttctcacct gagcaagctt tcgatcattt aggatctcaa cctgtgtgcc
     6781 attgagacga taatcacctg aggttggtct atctaataag ccgatgatat tcatcagggt
     6841 tgatttccct gagccagaag gccccataat agcgacaaat tcaccctcat atacagtcaa
     6901 atccacgcct tttaggacct gtagctcctg atcaccattt tgatagcttt taacaatgct
     6961 ttttaattgt attaattctt ttttctcatc tggcactact taatcacctc ggattcttta
     7021 ctgctttttt tagaatcttt tgatgccttt gtgtctgcgg aaataacgtc ttctagcttt
     7081 tcaccctctt tgatgttctt atcagggtta gcaatgacaa tatctcccac ctttagacct
     7141 gcacttactt cttgtctttc agcatcagca ttgcctaggg ttacttcaac ctttttagcc
     7201 tttgcagttg agtcatcata gacccagaca aaatgcttct tgcctttgtt aacgatagca
     7261 gtaactggta ctaaggcatg ctttgcttcg ttgataacct caacagacac cgtaaagcct
     7321 tgctttagct ggttaagcgg actcgtgata tcaattttgt agtcataggt cgcaccagtt
     7381 gagcttgatg agcctgagcc tcctgcagtt gaaccacctg cattggcatc ggttgggtag
     7441 tttgacacat aagaaatctt tccggtccac tcttgatcag catagacctt tgatttaatc
     7501 ttcacagctt gtccaacctt aatattggct aaatcatact ctgttagggt ccctttgacc
     7561 tgtaacttgc cttcggttgc gacatgaacc aaggtttgac tgttttttga agacgggtca
     7621 atatcattat taacctctac aactgtccct gaaacaccac tgacaactac tgtttcattt
     7681 aaggcctgct gtgctttatt gacctctgct tgagcatcag cataggaatc atttaaatcc
     7741 tgcaattgct gagcatagct agcattttgc tgggctgagg gctgaatggt tgtggtggtt
     7801 tcttgccctg tctcctcgtc cttgcttgtc tcagtagttg ctgctggaac accatacgtt
     7861 tttaaatgat taatctgacg cccaatttta ttgagattgc gaacagcggt gtcataagct
     7921 gcctgtggta cagttgtatt gtactgtact aactgctggc cttgtgtgac ctgatctcct
     7981 accttaaccg taacggtagc gtctgagcct ttgctagcat caaaataaac atattcttct
     8041 gaaagagctt taacagtacc agagagtaag gttgaagagg ctattgtccc ttctgttaca
     8101 tttaccgcag aataaggtag cttgatattt tgatcagaga tagtatcttg ctgttgcttc
     8161 cacaatactc caccgataac gactacagtt agtgcaactg cacctgcgat aatgcctttg
     8221 gttttcgttg ataactttat ctttcctctt ttagacattt ctgtcctccc cttttgtact
     8281 atttttgtaa gacaagtata tgatgttttt aaaaacttgt caagaatttc ttggataagc
     8341 ttaataaagc agcctcttca tcatgtagat gacaactcta ttataatggt ttttcaagct
     8401 gtactagctt acacttttgt aatattaaaa agaggcaaag acaaaaagag ttgtccttta
     8461 actttattac acagtctcat tcattaaaaa gcgaacaagc ctagttttca aaatctcaga
     8521 aaactagact tgttcgtttg tttagacttt tctctcagtc tcttcatcag gtttaaatag
     8581 cttctatact aaaggtacgg ctttcaagaa ctctcagcat tgctactgct gtatccaatg
     8641 ctgtaaacag aggaactcct tgttcgattg ctgagcttct gatcatctgc ccgtccttat
     8701 cagtcactcg ttttgttcct acggtattaa taatagcttg aatctgccct tttctcagta
     8761 aggctgggat atcatgagca ttgtcgccaa tttttccaac tagctgtgaa tctagccctt
     8821 ggtcagcaaa gaaagcagct gtgccttcgg ttgccatgat ctggtagcca atagcactaa
     8881 agcgtctagc taagatcaga gcctccgact tatggtcatc agcgatggta aaaactattg
     8941 ttccatattc cggcatgtgc agatagctag cttcaaaggc tttgtaaagg gctttttcaa
     9001 gtgttaaatc agagcccatg acttcaccag ttgatttcat ctcaggccct aaaaggctat
     9061 ccaccttagc gagctttgca aatgaaaaaa ccggtgcctt gatatgaaca agcgagcttt
     9121 caggataaag gccatcttga taacctaagt cttttaaggt ctgacccaga ataagcttcg
     9181 tagcgacttg tgccattgga atattggtta cttttgataa aaatggcact gtccgactgg
     9241 cacgaggatt gacctcaatg acatagacct gctcattttg gatcacaaat tggatattca
     9301 tcatgccaat acagtttagc cctatagcaa gacgcttagt gtaatcaaca atcttgtctt
     9361 gaacctgttt agataggtgc tgcggcgggt acacagccat tgaatctcct gaatgcactc
     9421 ctgctctttc gatatgctcc atgatccctg ggattaagac tgattgaccg tcagagattg
     9481 catctacctc gcattcctta ccaaggatat aagaatctat taaaacagga tgctcaggac
     9541 tagccttgac agctgttttc atgtaggagc gtaaatcgtt ttcattttca acaatttcca
     9601 ttgctcggcc accaagaaca taagagggtc tgaccaatac cggaaagcca atggcacgcg
     9661 ctgcctctaa ggcctctgcc tcattggtgg ctgttttccc aggaggctga gggatcccca
     9721 gctccttcaa ggctttttca aaaagctccc tatcctcagc acaatctaag tcctctagct
     9781 gtgtgcctaa aataggaact ccggccttgg ttaactgctc tgctagatta atagcagttt
     9841 gtccaccaaa ctgtaggatt actccctttg gctgctctaa ttcaataacg ttcatgacct
     9901 cttcaaaggt taagggttca aaataaagct tgtctgatat cgaaaaatct gttgacactg
     9961 tttcaggatt tgaattcatg ataatggctt catagcccgc agcctgaata gccttgacag
    10021 aatgtacggt tgcataatca aactcaactc cctgaccgat gcggatagga ccagagccaa
    10081 ggacgataac agattctttc tcggatttga ttgattcgtt ttcccactca taggtcgagt
    10141 aaaaataagg cgtttgtgag tcaaattcag ctgcacaggt atcaaccatc ttataaactg
    10201 gcaagacacg ataggctcgc cttaaccgtc taatacttgc agcatcagtt tgccaaagct
    10261 ctgcaatttt ttggtctgaa aaaccatatc gcttggcttc tatcagcaaa tcgatatcaa
    10321 ctggcttttt aataaggtct tgctccagtt ctacgatatg acgtaattta tccaaaaaga
    10381 ataaatcaat cttggttaag ccagctagct cttcaatact atagccacga cgaagggcct
    10441 cagaaagata gaatagacga tcgtcctgtg ctcttacaat gtgagcaacc agctcatgat
    10501 cactgatagt atctagaccc ttcagttcgt tatggtgtac tccaatttcc aacgagcgac
    10561 aagcctttaa gagacattcc tcaatacggc gtccaatagc cataacctca ccagttgctt
    10621 tcatctgggt tcctagacga cgctcccccc gctcaaactt gtcaaatgga aagcgtggca
    10681 gcttggcaac cacataatca agagctggtt caaacatggc ataggtggtt cctgtgaccg
    10741 gattaagcat gtcatcaagc cttaagccaa ctgcaatttt agcagctatt ttagcgattg
    10801 gataaccagt tgcctttgaa gccagtgctg atgagcgaga tacccgcgga ttaacctcaa
    10861 tcacataata gctgaagcta ttgggatcaa gtgccagctg aacattacag cctccttcaa
    10921 tcttaagggc acgaataatt ctcaagctag catcacgaag cagctgattc tcaacatctg
    10981 atagggtttg tgtcggggca aaaacgattg aatctccagt atgtatccct actgggtcaa
    11041 aattttccat actgcaaaca accagcgcgt tatcagcagc atcacgcatg acctcatatt
    11101 caatctcttt aaagccggca atggagcgtt caatcagaca ctgggtgaca ggagatagct
    11161 tcaggccatt ctccacaata tctcgcaaga cctcttcatt ggagcaaata ccacctccag
    11221 tgcctcccag agtaaaggcg gggcggacaa taacagggta gccaatggca tttgcaaagc
    11281 cgatagccgc ctctactgtc gtcacaatct ctgattctgg aataggctct cccaactctt
    11341 tcattaattg cttaaataaa tcacgatcct ctgcctgatc aatagcagat aaggttgttc
    11401 caagcagctc cactcctaat tcttgtaaaa taccagcctt agacagttcc atcgccatgt
    11461 taagaccggt ctgcccacct aaggtcggca gcaaggcgtc tggtctttcc tttcttaaga
    11521 tacgactaac aaatgccaac gtcaggggct cgatataaac cttatctgca acctctttgt
    11581 ctgtcataat tgtcgcaggg ttagaattaa ccagaacaac ctgatagccc tcttccttta
    11641 aggctaaaca agcctgtgtt cctgcgtaat caaattcagc tgcctgccca ataacaatag
    11701 gaccagaccc tatcaccatg atttttttaa tatctgtacg ttttgccata atatctggta
    11761 caaaaggcct taacaatccg aataaaataa tgcaagcacc taacattaaa gcatcacaat
    11821 ctatttttta ctaggatttg tacctgtact cagctgcagc aagccctttg tacctactcc
    11881 tttcattatt tgccgtctca cagggcggca ttaaataaaa cacttaacag tctgtcacat
    11941 gagacgatga gtacaagatc aagtaaccct tagctcagca agtatagatg acttaattga
    12001 tatagtcttt ttacttctaa agagggcgat cttgccagca aatactagtc ataacccgcg
    12061 gcagagcgat catttcccac tagtctatct gctgcctgac tcaagctgtt tcatgacagc
    12121 tgatcaagcc tttggtgctt gctttttgat ctgctagcac acttgattaa catttgcctt
    12181 gctgctctag ctgccaggcg tcaatcatat ctaaaaattc atcaaataga tagctagcgt
    12241 catgagggcc tggtgcagcg tctgggtgaa actgcacaga aaaggcggga acatgtcgat
    12301 gtctcacccc ttcaacagtt ttgtcattaa tctcctcgtg cgtaaccatc aagcagtctg
    12361 gcaagctgtc gcgctcaaca gcataaccat gattttgact agtaaaatca atacgtccgg
    12421 tcgctatttc tctgacagca tgattaaagc cacgatgtcc aaaaggcatt ttaaaggtct
    12481 tagcgccatt agctaagcta agcagctgat ggcccataca aatgccaaaa attggaattt
    12541 ttccttgaac accacgaatc atctccaagg cctccggcaa atcctctgga ttacctggac
    12601 catttgatag cattagacca tctgggttga gctgtagaat ctcttctgct gtgatatcaa
    12661 aggggactat tgtcatctga cattgccttt tggataattc tcttaaaatg gaatgcttca
    12721 agccaaagtc caccaaaaca atatttttcc caacacccgg agcgggatag gcagtcttag
    12781 ttgacacctg ctcaatacca ttagtcggaa gcacagttgc acgcagctga tcctttaggt
    12841 gttcaagcgt atcaccatca tctgccattg ttgccttcat cgtaccatgc tgacgaatga
    12901 ttttggtcaa cgctctggta tcaattcctg aaatgcctgg aatcccctta tgctttaaaa
    12961 actcgtccaa ggtcatttgc tgacgccaat tgctagctat cctgcttact tcagagacaa
    13021 tgaccccttt gcaagttggg gcaatggact cataatcatc acgattaata ccataattac
    13081 caacaagggg ataggtaaat actaagagct gcccgttata ggactggtct gtgattgact
    13141 cctggtagcc tgtcattcct gtattaaaga caatctcgcc agtgacatca atatctgcac
    13201 caaagggctt tccttcaaaa atggtgccat cctctaagat aagtaaccgt tttgccattt
    13261 taaccccctc taacatgcct ttagacctta tcgtttctgc cattaaggat cgcttcgata
    13321 atggccatac ggacaaatac accattagcc atttgagcta ctattcttgc ctttggagcc
    13381 tctactaaat ggtcagcaat ctcaacatcg cgattaaccg gtgccgggtg cataataatc
    13441 gcagagtcct ttaaccgcct gtagcgctcc tcagttagac caaactgtct atgataatct
    13501 tccttggaaa agctttgact accatcatgg cgctcatgct gcaccctaag cagcatcaac
    13561 acatctaatt gatcaataat gtgatcaatc gccatgtacc ttccatagct gtcaaattca
    13621 gacgagtacc attgctcagg accatagaaa taaagctctg ctccaagccg ctttagaatc
    13681 tgcatgtttg atttagccac acgagaatgt gtcaaatccc ctgcaatagc aatcttcagg
    13741 ccatcaaaat gaccaaattc ttcataaata gttagcaaat caagcaagca ttgactaggg
    13801 tgctgacctg atccatcacc tccattaacg atagaggcag taatcgttgg actgtcaata
    13861 agctgctgat agtaatcatc ttctgggtga cgaatcacgc agatttctgt tcctagagca
    13921 ctcatggtaa gaacagtatc atataaggtt tcccctttat tgacagcact tgtatcagcg
    13981 ttaaaatcaa ggactctaag accaagcttg ttctcagcaa cctcaaagga tttatgggtt
    14041 cttgttgaat tttcaaagaa taaattagct gcaaagtgcc tactgttatc tttaatagct
    14101 accttacctg ccttgtattc agagccacga ctaataagtc ctaaaacctc ttcatttgtt
    14161 aaatgctcca ttgacaccaa atgcttaagc gcaacacgat tatttacaac tgacatgatt
    14221 tatccccttt taccaataat gaaatgatga taacaattga caacagctac acactagttt
    14281 tctggaagaa gctgatacaa tataatgcca agaagcgttg aaaaagcaac acccgaaatc
    14341 tgaaggccat tgatttgaag catgaggcct ccaataccag aaaccagaat aacactagca
    14401 atcaataggt ttttcttgtt gtccatatca accttagctt caatcaggat tttcaagcca
    14461 ctagaggcta taaccccaaa cagagcaatc gaaatccctc caatcactgg agtaggaata
    14521 gactgaataa gtgctgatac cttaccaaca aagcttaaca aaccagcaat cacagcggca
    14581 cctgcaataa catagactga gaagatttta ttgagggcca tcacaccaat attttcacca
    14641 taagatgtta ccggaggcgc tcctaaaaat ccagcaatca cctgtgcaag gccatcaccc
    14701 gtcaaggttt tttccaagcc aggatccttg aaataatctc ttttagtcag gctattaagc
    14761 accatgatat gaccgaaatg ctctgtcatg gtgacaaagg caatcggggc catcgttaaa
    14821 atagcactag gatacaaggt aatgtcatag gttaaaaagg ggatagccac agctggaaca
    14881 ctgagccatt gggccttagc aacctgtgta aagtcaacaa tagactgacc cgtcaccata
    14941 ccaacaagga tcgcaaacaa atagccaacc aataagccca acaaaatagg aatgatggcg
    15001 acaatccctt taccataaat gttaaagaaa ataatcgcta ataaggtgac aagaccaatc
    15061 aaaaggtata acaggttata ctttccatcc tttagcatga catcactaac tgctgttgag
    15121 gccaagctaa gaccgatcac cataacaatg ggaccaacca caactggagg taagatctta
    15181 tcgatccatt cattgccaat cgccttcacc accagtgcta caaccagata aaccaggcca
    15241 cctgtaatcg ctccctgtgc aactgcacca ataccatctg ttttcattag catttgcatg
    15301 gctgcaatat aagcaaagct tgagcccata taagcgggaa ttttaaatgt tgttactgac
    15361 aaatgcgcca gagtcccaag tccacttgat aagagggcaa ctgacggatc aatcccaacc
    15421 aaaattggaa ccaaaacagt tgctccaaac atagcaaata aatgctggaa ggacaagcca
    15481 agcaaaatcc ctgcctttgg cacttcttct acatcataaa tgacatcttt cacacaatca
    15541 cctctttctt atcccggatc aacaatacta atacgatctt gaccgtcaac ctcaaccacc
    15601 tcaacgacaa tctcttctgt cttgcttgtg ggaatattct ttccaacata atcggcccga
    15661 attggtaatt cacgatggcc tcgatccacc aaaacagcta ggctaacacg tccaggacgc
    15721 cctaagctaa ccaaattgtc gatagctgcc cgaatcgttc tgccggtata aagcacgtca
    15781 tctactaaga taatatcctt gccggtaata tctaccggca tgctggtggt gtcctcttcc
    15841 actctcatat catctctaaa gggcttggta tctagctctc caactgccaa gtgcaggctt
    15901 tctagctgct ctaatctttc ttgaatacga cgagcaaggt aaacacctct tgttttaatc
    15961 cctacaagca ccacattgtc tagttgcttg ttgcgctcaa taatctcgta cgtaatccgc
    16021 gtgatcgcac gcttcatggt tagctcatca acaattacct ttgatttcat tcaaagcctc
    16081 ctcaaaaaat tcaactaaaa aaatctccct gttaacaagg agattcagca aaacaggcac
    16141 acagctagac ataactgtgc acttttttat tcagaacatg ctccttgcca gcctcacagg
    16201 actgttttaa aggaatattt tattttcatt agtatagcaa aatcacaagc caaaaacaag
    16261 gattttctaa aaaataattc aaaatatata gagctatcac agcaccaagg aaaatgctac
    16321 taaggtcatc agcaatcctc caacacaatt ccaaaaatag gtcttaagac ctattgtatt
    16381 tgtatcaaaa caatagtaca ataatatcaa acacaaagga gagcgtttat gatgaatgat
    16441 ataactagaa agattaacca taagcaactg attcaaatca ctaccattct aggcattatt
    16501 gttaccatcg ttattttgtt ctatctgcag cagcacccta atctttttgc agttggcggt
    16561 ccttttcaga cctatcttat ggaacttggt atcctagcac cctgtttgtt tatactgctt
    16621 caaatcattc aagtggttta ccctatcatt cctggaggct tgacctgtgt tttagggcat
    16681 gtagtctttg ggccgttttg gggatttctt tataatactc taggtatttt tattggttcg
    16741 ctgcttagct ttatgctcgc tagaaaatat ggtgaacagt ttgctaaagc ctttgtatca
    16801 gatgatacct ataacaaata cattccttac ctcaataaag gcaagtactt tgaacgattt
    16861 ctcataacag cctttattct ccctggcttt ccagatgatt ttctctgtat ggtagctgga
    16921 ctaagcagca tgtctatcaa aacatttacc agtattttct tgatatcaaa gccaattact
    16981 ctttatatct acacccttct tgcttaccaa ggcatacaaa tcgttggaca ggtattgcaa
    17041 tcctaaaaaa agctagtatt aagctatcaa gcctgattgg aatacagtat tccaatcaaa
    17101 aaggcgctca gcttggtacc agctttttat ccttgtctta gttgctccaa agtcctttgg
    17161 aagatttctg gtggctcaac agtaaagacc agctcctctc ctgtcacagg gtgggttagt
    17221 cccaatgttt gcgcatgaag aaactgcccc ttgccagcca aggtcttacg aggaccgtag
    17281 agtggatctc ctgcaagagg gtgaccaata taagccatat gaacgcgaat ttgatgcgtt
    17341 cgacctgttt ccaattgtaa ttccacgaag gtatagtggc caaagcgctc caaaacctta
    17401 aaaagagtca aggcttcctt gcccttagca gttacggtct gttttttacg atccttttca
    17461 ctgcggccaa tcggagcttc aattacacct cgatcctttg gtaaattacc atgaacaatg
    17521 gccacatact ttcgtaagga tttcttagcc ttgagctcat cagctagtag ctggtgggcc
    17581 ttatcggtct tggcaaccat taaaagacca gaggtatcct tatcaattct atgcacaatt
    17641 cctggacgaa taacaccatt aatagaagac aggtctttga tatgatagag caaggcattg
    17701 accagcgtcc ctgtagaatg ccccgcagaa gggtgaacaa ccattccctg aggcttatta
    17761 ataatggcca atacatcatc ttggtagaca atatctagtg gtatatcctg agcctgatag
    17821 tccaagctgc tttcctctgg gatatgatag ctaatgcagt cacccacctg cacaatatac
    17881 ttggccttct taggtaagcc attgaccaat accctttttt gcttgatctg atcattagcc
    17941 tgacttcttg ataatggggt caaatcagcc aaggccttat ccaagcgatg gcctgattct
    18001 gttatcttaa tttccatagt cctcttcttt ccatagacaa atgaccagca gcaaaacacc
    18061 tatcgtcaaa taggaatctg ccacattaaa aatagcaaaa ttgatcacat ctaaatgaat
    18121 catatcaacc acataggata acctcaagcg gtcaataaaa ttcccaagac ctccagatat
    18181 aatcagcaat aaagagagct gtagccaaaa gctagccttt gggtgcttca acacataata
    18241 aatggcatag ccaaccacca aaacagttat gattgtaaag aaccactgct gattctgtag
    18301 tatggaaaaa gcagctcctc gattttgaag ataggtcaag ctcaccaaac ctggtataaa
    18361 gggcttcacc tgccctagct caatatgtgt aacagtccac catttactta gctgatccag
    18421 tatcattaag acaatggcag ccataataaa actaattctt ttcaactaat cctattcctt
    18481 tcagcttaaa aacaagagat taccttgatg gcttcaaaaa agcaacaaca gccagctgtc
    18541 tctgtagcgt actcaacctt aaagcctcca aaaactggta ttctagtaac cttttagtat
    18601 cattgatagt caaccacaca gcagctctag acttgacttt atatcaacaa gtctcaccac
    18661 agcagctcgc ttaatcctta tccataccag agctaagtcc cattgtctat agcttgcttt
    18721 tcttttcgat gttcaaaata atcctgtaaa atggtcacaa aatgtaaagc cgcagcagat
    18781 aggttcttat ccctacgctt gacataaatc attttatgct ccatatgatc acgcaaggga
    18841 ataaccttga tgccattaac gctttgctga tctaaaaatc cagaccctgt tgcaaaggca
    18901 gctgtccttt ccaaaatgcc atttaaggtt gccctatctg acacagtgta tatgtgagga
    18961 ctcttgcttg tgtcaataaa attttctgaa taataaagat attcttcttt ttcttgagta
    19021 aagcgtaccg ctggcagccc ttgcaaatcc tctaagaaaa gggctttcct ttgagccaat
    19081 ggatggtttt ttgataggta aatatgggtt gtaaaggata gcaattcaac ataatccaaa
    19141 gccagcttat ccattcgctg aaaaagcccc tgacggtttt gtgcattaag atagataatt
    19201 ccaagctcac tatttccctg tgccacctca tctaaaattt gcatagtcgt tgactcaaaa
    19261 actctaaaaa ccttatgccc agcatgcttt tgggaaaatg ctgttattaa agctggtaaa
    19321 aaatcataat gctgactcgc aattgaaaat tcatttggct ccaaagccga ttgagaaaac
    19381 tccttttcca gcgagtcaaa gcacttaaca acctctaagg ccttttcata aaataaaagc
    19441 ccctggctgg ttaacacagt tcctgctgtt gtcctacgaa agatctgaaa gccaagctct
    19501 gtctccaaat ccttcactga aacagacaaa ctgggttgac tgacaaatag ctttgaagca
    19561 gcctcacgaa aggtaccatt atttgcaata gcaaccacat atcgtaattg ttgaatattc
    19621 attaatccac ttcctaaatc tagtaccctt cattatacca taaagccagc caatgaaaaa
    19681 taaaggcgtc catcttaacc atgccaaacg tatctacaga taatcatgag atagcattga
    19741 ctttttcaat agtgtcttat catatttagc tatagaaaac agccttacta taagttatac
    19801 ttttgaaaga agtaagcctt agatcacaga acatcacact gagatttttt atgcgcttat
    19861 cctgtctgtc caagaactga gaattggcta catctagcta ataagccatt tcaggatttt
    19921 actgtctagg agttatttat aggcaactat tacagtaaga tagtgtcaca atacaaaaaa
    19981 ggctatccca aagtacagaa cagccttata ccgtgccctt ttaacacatt attttgcgat
    20041 tgggtataca gaaacttgtt tcttatcgcg tcccttacgc tcaaagcgta caacaccttc
    20101 aaccttagca aaaagagtat catctccgcc acgaccaacg ttaacaccag gataaatatg
    20161 tgtgccgcgt tgacggtaaa ggattgaacc tcctgaaact gtttgtccat cagctgcctt
    20221 agcgccaaga cgttttgctt gtgaatcacg tccgttagaa gttgaacctc cacctttttt
    20281 gtgggcgaag tgttgtaggt tagaaagatt aagtttaatc atttttattt cctctcgttg
    20341 aatttaattc atcacaggct tttgaacata ttctgataaa tgctctgcca aattctccaa
    20401 gccaatcaca acagactcaa acagaatttg ccacacctgc tcttgttgct cagtaaatcc
    20461 ctcaggcttt gttaccctta ggaatccacc accatcgacc atttctagtg ctggctcaag
    20521 acctgtcatc tgttcaactg aattaacaag attgaaggcc aaaactgaaa ccgaagcaca
    20581 aactacatca aagccgtact caccgcttcc agcatgtcct gtgataagca tctcagtcca
    20641 gccagctgcg tcttttgtta accgtacttt aatcatgtca aactagaatt atgccttgat
    20701 agcgttaatc acaactttag tgtaaggctg acgatgacct tgcttacggt ggctaccttt
    20761 tttaggcttg tacttaaagg ttacaacctt cttttgtttt ccttgctttt caacagttcc
    20821 aacgacagta gctccctcaa caactggagt accaacgaca gtcttatcac cacctacgag
    20881 aacaacctcg ttaaaagtga tttctgcgcc agcttcagcg tcaattttct caacgtagat
    20941 tgcttgacct acttcaactt taacctgttt tccaccagtt ttgatgattg catatgtgct
    21001 catgatgcac ctcctataag atttttgatg aggtttccct ctgtgaagac tcgcctagaa
    21061 tcgtgagagc caatctactt gaaaacgatt ttcgtgcggt tgcacaggac gtgcacttag
    21121 tcaacgttac aattttaaca tcaaatttga tttttatcaa gaaaaatatg cttttatctt
    21181 cctaaaatct taagctatac ataatcacag ctatgtaaag gctagcaatg ctttaccatt
    21241 ttaggttaac cagggcattc atttctttat aagcaatagc tgctttttct tgcgtttcgg
    21301 gatcaatctt atcataatat ctgccgcctt tgataaagtc ctccaaaacc atggtacgat
    21361 agctatatag ctcatagcct tcactaccat aaaggccctt aggcttagct aaaaccattg
    21421 tcgggtgagc ctttactgtt tttatttttg ttttttgccc cttcttctca aaggtaaggt
    21481 ccattagcac gccgcgctct gtccaaatat catcaacagt ctctaggcgt tgattggaaa
    21541 tgaaattacc cattgaatag ataataaatt tcttttcctt gtccttaaca atcgtctctg
    21601 ccggctctac gacgtggggg tgacctccta agacaacatc agcaccccag tcaatcattt
    21661 ttcgataaag agttttttgc tcagctgttg gctctaaagc atactctgtg cccatctgcg
    21721 gcataacaat ggtaatatcg gcctcttttt cagcacgcaa gatgtctttt tgtatctttt
    21781 cctcattaag gtcagacagg tgcttgtcat actcctcctg actgagtgtc gcctccattc
    21841 cattatagcc atatgaatag cccaatattg caatcttaat cccattaacc tttttaatga
    21901 gaatgttctc cttagagcga tcctgctcat aaataccaat gctgtctatc cccatatcag
    21961 caaaaacacg cttggtattg agagctcctt ctaatcttga gtccaaaata tggttatggg
    22021 ccaaatcaac cacatcatag ccagtatgct taagcgcagc agcaatagcc tctggcgcat
    22081 taaacaaagg atagccagct agaggatagt ctggactgat cgttccctca tagtctccaa
    22141 tggccaaatc agcctgacta atccaatcct tcacatactc aaaataggga ttaaaatcat
    22201 agctaccatc agccttttta gcactcatat agagaatatc atgaatcaaa atatcaccat
    22261 ttgcgacaac acgcgctgtt tgtgtctttt gaggtgtctt gcttttcgtt tgtgtgcctt
    22321 tttttgacat gcctaataaa tcaaaggcca acccaaaaac aagtatcacc acaatcaagg
    22381 taagcactga aagcatggtc tttttatact gaaaatcttt tagcaagcgt caaacctcct
    22441 tttttcctat tataccatgt tgacacgact ttttaataac aaatcccaaa gaaaaggcta
    22501 tgcccattta agaagaatgc cttagacagc agcatagact cgtattagct agtcaaaaaa
    22561 ctagattgct cctctttggt tgatgtcata tactttgagc ctaaatagct ttcaacaaag
    22621 tctaatagtt gaataatgtc atgcaaaata tggtataatg aaacaaaatc aaactagtca
    22681 ggatagtcac atgaagcata actctttcag ccgctcacta ttactccccc ttctcatctg
    22741 ttccttgtct gcttgctctt ctcatacaga gaaaaaagac cataccaaag acgctactgc
    22801 tatcaccgat acccgaaaag cagagcatca ggacatcagg gcaaatatgg aaaaggtcaa
    22861 gctcgctacc gctagcaccg acttcaaagg tggctcaagc cttgaggagc taatcactat
    22921 ttttggacag cctagtcagc acgaagaaaa agcagctggt agtgttactc ttgactccta
    22981 cacatggcag tttgaccatg tcacggttaa tattaacctc tatgaaaaca gcagcattgt
    23041 taaaactatt gctaactttg cttttattag agacctgacc ttatccttaa aggactacaa
    23101 cagcttgaaa aagggcatga cctatgatga ggtcaagcag ctattgactg agcctgataa
    23161 ttacagtcaa gccaattcca gtgaaaaaga aaccattcaa gccatttgga ttagtggctt
    23221 aaaagctcag acacagggtg ccaatatagc actaaccttt gaaaacaacc agttgacaga
    23281 aatgtcacag gttggtcttg aagactagtt tgtggataac cccaatcata ttaatgatag
    23341 aaaaaagctt gatatttaat aagatcaagc tcaaacgata gaccaagtag ctgatgatct
    23401 tgacagtaat gtgtaacaag ctgagatact actcactagg cagtatttac tagcagccac
    23461 tgaatttcct ttatgatgac aggcaaccac cttttttgtg gtgacctatc aatagcacca
    23521 taagctctct tttgtcacat accttgctta acattatttt accaggtatg tgatgagctt
    23581 tttaggttgt ctgatagtat aacatctaac ccctagttga tgatgtagat aaggcaagag
    23641 ctgctaagga tagcaccata aataagatcc aacatagggt catattatat agtgccaaga
    23701 acgaaaagat aaagacacct acagggagcg ataaagagaa cagaagacct aaaaagttat
    23761 tgctttgggc tagcatatct gatgggagat tttccattaa aagggcgtcc agcttgggtg
    23821 tggcttttcc cataatataa gctgcaaagg ctaagcataa aacccctatg atggcaggta
    23881 attgcagagc attagagact cctaccagca aaaatgctat gccctgagtc tgtactagct
    23941 ttgatattga aagccttgaa aagtaatcct ttggtgttag atttcccaac atcgctccga
    24001 taatcgtaac ggcatcaaca ataactaaag actgcccata atgaaaatga aatagctgat
    24061 gatccatcaa ataaaaatga taaatgctat taattgctcc tccaatagcg tttaaggtca
    24121 agatggataa gagtaacatc acaaaagaga tatgatcaat ctttttaaag gtctctgtca
    24181 tccttgtata catcacctta aattgcttca ttaatgaaac acctgcttca gaagcttcaa
    24241 cgacatcatg ccttagcttt tgtcgatttt taagaagcac aacagatgac aataaaaagg
    24301 aaatagcatt tatcaaagca acaaaggcat aattgttgcc tgatgtcgtt agcagccaaa
    24361 ctcctaaagc ttgtcctgca atactagaga ggtagccgat aaattgagca aaagaatagg
    24421 cctcatagag cttttctgat tcaatatttt tctgcattat cgggagacgt aagccatttt
    24481 tgtaatcact tagaatatca gaaaccacat tcaaaaagcc cacaaaggca aataccaaga
    24541 acgtctgatt tgtcatcaac aaggctacaa gcgtaaataa aagagattgt ataaaaccaa
    24601 taacaataag atttcttgtt ttcctttttg tcttatctgc tttgacgcca atccaaaagg
    24661 taaacaccat aggaatgatg gtgatgatat tggctataaa aacagcaata tgagaataag
    24721 gtagcgtggt tgcataaata ataaaaacaa tattgtaaat ataagagcct aaagcactta
    24781 aaaagtttga aactgtcagt gttctaaaaa cgacattttt aatcaatccc ctcatttact
    24841 tacctgttga cgtcctttct tatgtcacct tactttactt gattgaatat acttacagca
    24901 tatctaaatt cgtactgtag ttttatatgg tgttctgaca tgattttgct actaattagt
    24961 aattcacaag ccttttctaa gtataaagta tcgtttgtta gtctaaatac ttgtaaaagt
    25021 gtcatggcta tccccagcat tccgttccat agaccactaa actgagcaaa ttcaactaat
    25081 aacgactccg ataaattctt aatatcttta atatatttat cggagttaac gtaaataagc
    25141 aattga
//
LOCUS       DARYLD010000032        22791 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYLD010000032 DARYLD010000000
VERSION     DARYLD010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22791
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..328)
                     /locus_tag="TU651_001144"
     CDS             complement(<1..328)
                     /locus_tag="TU651_001144"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897153.1"
                     /translation="MNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVAREKL
                     INTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDNGA
                     VSTKADF"
     gene            complement(470..892)
                     /locus_tag="TU651_001145"
     CDS             complement(470..892)
                     /locus_tag="TU651_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897154.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(1215..1475)
                     /locus_tag="TU651_001146"
     CDS             complement(1215..1475)
                     /locus_tag="TU651_001146"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897155.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(1490..3298)
                     /locus_tag="TU651_001147"
     CDS             complement(1490..3298)
                     /locus_tag="TU651_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897156.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(3939..4838)
                     /locus_tag="TU651_001148"
     CDS             complement(3939..4838)
                     /locus_tag="TU651_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL0897157.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(4850..5659)
                     /locus_tag="TU651_001149"
     CDS             complement(4850..5659)
                     /locus_tag="TU651_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL0897158.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(5643..6002)
                     /gene="rnpA"
                     /locus_tag="TU651_001150"
     CDS             complement(5643..6002)
                     /gene="rnpA"
                     /locus_tag="TU651_001150"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL0897159.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(6494..7234)
                     /locus_tag="TU651_001151"
     CDS             complement(6494..7234)
                     /locus_tag="TU651_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897160.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(7238..8536)
                     /locus_tag="TU651_001152"
     CDS             complement(7238..8536)
                     /locus_tag="TU651_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0897161.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(8548..9894)
                     /locus_tag="TU651_001153"
     CDS             complement(8548..9894)
                     /locus_tag="TU651_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0897162.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
     gene            complement(10339..11784)
                     /locus_tag="TU651_001154"
     CDS             complement(10339..11784)
                     /locus_tag="TU651_001154"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL0897163.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
     gene            complement(12386..13099)
                     /locus_tag="TU651_001155"
     CDS             complement(12386..13099)
                     /locus_tag="TU651_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL0897164.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            complement(13227..13733)
                     /locus_tag="TU651_001156"
     CDS             complement(13227..13733)
                     /locus_tag="TU651_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL0897165.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            14116..14394
                     /locus_tag="TU651_001157"
     CDS             14116..14394
                     /locus_tag="TU651_001157"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897166.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            complement(14555..15916)
                     /gene="radA"
                     /locus_tag="TU651_001158"
     CDS             complement(14555..15916)
                     /gene="radA"
                     /locus_tag="TU651_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL0897167.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(15983..16429)
                     /locus_tag="TU651_001159"
     CDS             complement(15983..16429)
                     /locus_tag="TU651_001159"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL0897168.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            complement(16631..17398)
                     /locus_tag="TU651_001160"
     CDS             complement(16631..17398)
                     /locus_tag="TU651_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL0897169.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            complement(17560..19356)
                     /locus_tag="TU651_001161"
     CDS             complement(17560..19356)
                     /locus_tag="TU651_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897170.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISAPKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            complement(19356..21065)
                     /locus_tag="TU651_001162"
     CDS             complement(19356..21065)
                     /locus_tag="TU651_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897171.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            complement(21058..21507)
                     /locus_tag="TU651_001163"
     CDS             complement(21058..21507)
                     /locus_tag="TU651_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL0897172.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            21717..22736
                     /locus_tag="TU651_001164"
     CDS             21717..22736
                     /locus_tag="TU651_001164"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL0897173.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
BASE COUNT         6761 a         5526 c         4280 g         6224 t
ORIGIN      
        1 aaaaatctgc ttttgtagaa acagcaccgt tatctactga taattgagca taatcatcta
       61 atgtttctac aaattcatca gcctgtctta tcgaaaccca actatttcct ttaagatccc
      121 tattaaaaat ttctatggct ttctccctaa atgtgataag atttagatca gcattctgtt
      181 ttcttaaagt attaattaac ttttctcttg ctacatagct cttaaacctt gagctctctg
      241 ttgccagcct gctgttttca aggttcttca aaagctgctg gcggttgtag gtcggtttcg
      301 tcaccctagc tgctattggc tcattcaagc taaaccgtct ggcggcgctt ggagacgctt
      361 ggcattggct tcaaggtgac gagctactcc ctgataagct gtcgcaggct aattattaag
      421 aacatgcttt aaaatagcag agctaatctc ggctccgcta tcttaaacat tatttcaaag
      481 gactgacata atcatctggc agttttccct tccaatctat ccatttttgc tctgcgattg
      541 gaatcagttt tcttagctct tcttgggtaa aaagttccca acttgttgga tctgcaatta
      601 aggctattgg ggatctttgt aaaaatgctt tatcactagc tattttctct tcttccgttg
      661 gtggccaaca atcatatcgc aatttaaaag caatctcccc taaattccgt tttccttgct
      721 ccaataattc aaataaatca tacggcagct catatactac tcgctgctca gctataccac
      781 cttcattagt cactagatag taagttccct gacgcttcca cacctgttga ccataaccct
      841 tgacttcctc atattgacta acatcttccc actctaattg actatgttcc atgtatgttc
      901 tcctttactt gtactgatat ctttcataac tccctctggc atatcacccg gataagtacg
      961 acctccaggt cgccaccagc tattagcacc cttttcatta ccacttggaa tagaaatccc
     1021 tttctccgaa acaacctctg gtgaaacatc taagcgatag agcggatcat tgccaagata
     1081 accctcgtcg aagccgagta agctttcata aaagattgat gcatagtcag cttactcttg
     1141 ttcctccttt cttcagtttt ttatcataat ttcatcttaa aatttaatca attcgagcaa
     1201 tctaatctca ctcatcatct ccttttccta tttaggcata cttctaagtc cttcaaagtt
     1261 tttaaaattg gactatcata ctgtgttgta tcatcaacaa attgtctagc taaacttgaa
     1321 aaattaatat tcccaacaat ccgattatta tcaatatcat tagtcaaaac ataaagatct
     1381 cttaatattc ctgaatagtt tttttgcttg ggatactcaa gttctattaa ctctctaagc
     1441 ctttgtgtat attgaaaaca gttattatta tccataaatt tctccttttt tagttaggaa
     1501 cgatccttat ttcttgaatc cactccaatg gccaccgatt gggaagtaag acctgatctc
     1561 cacctccaat taaggttgtt cctgaagatt taaccgtctg tggggcaacc ttgccaatat
     1621 tcaattgact cccctttggt attttaatta cagcctcata ttgtctagta tttttccatt
     1681 ctggaagtaa agctgtatct atttttgctt gtatacgatt agttgcaggc accgttgtga
     1741 caaaaccgcc tccagcatct gacgcccctc caaaagtcct ataaagtgtt atttcctcac
     1801 ctgtaataac tgttctatag tgactatctg taaatgaatc tgcaatccaa ccaggaagat
     1861 tttccttagc cccaactgtt actttactat ctatttgagt tggatatttt gtaacacttt
     1921 ctttttttat atagcctccg aaattagaac tctctctcgc cagcctgctg ttctcaaggt
     1981 tcttcaaaag ctgctggtga ttgtaggtcg gtttcgtcac tctagctgct attggctcat
     2041 tcaagctgaa ccttctggcg gcacttgagg cggcatagcc tgctaggata ttccctacca
     2101 aggtagctct ttgggcatct tgctcactgc cgcctaagag cttggtgcca tgatagctgg
     2161 cctgaccacc gataaagccg ccaacctcac cgatcgtaaa ctctgtcaag cccttggcaa
     2221 cactcttggt ctgaccaatc agaattagtg ctgcactggc tgttgtgaac agcccgccga
     2281 tctggtgata aagcctgtca ttccccatga acaaggtatc ccgaagggga ttggtagcca
     2341 ctgtaagccc atcgccaacg ctacctagat aaatgttgtg cccagcctca tacaggttcg
     2401 acgccccata agcaactgta ccactgccaa caacaaaggc cccaaccacc aagggagtcg
     2461 ctgcccctgc tgtcatgacg atagccgcaa ccccaaccgc tattgtcaca aggctgagtg
     2521 ctagatctat ccagccctgc ttggccctgt cctctgcagc tactgcctca aaacgggcat
     2581 gatcccgctc ctgcgctgct tggagacgct tggcattggt ctcaagatga cgagccaccc
     2641 cctgataagc tgtcgcaaag cgttttatgg tgttgagctg tcctatatcc ccaacctgat
     2701 agctcccagc ccgcttgggc ttactgctgt actctgctat caaggccttg gtcgaagcca
     2761 aaagctcctt gaaggcggcc aagtcctgac tggcatgatt gctttcgtat tgaatgatgg
     2821 cctcgtccaa gcgatggata tcagtgatca gctcactata atccactact gtcttggcat
     2881 gactgacacc agagtagtga accaggtctg ataacttagc tctggtattc tgtagtagct
     2941 caagctgatc cttgaggtgg gcctgcgaga gccgaagctc tgactgcagg gtcttaaaga
     3001 cctgaccggg taactgggca tgactattac tgtctatctg gtaatagccg tccttataca
     3061 gcaagaggct agctgagtaa tcattcatca ggctttgcag ggtttgtaaa agtgtcccat
     3121 gcacctcact cagatagctc ttgattgagc tagcggtctg accctgaagg cgactgtctc
     3181 caatcaaggc tgacagggcg gtctggatac tcgttatccc atctccccaa gcactgatcg
     3241 tggtttgggt gctttgttga agggaggtaa tctcatcata tttgatatta tagctcattt
     3301 cttcccctaa cgttttcaat gcgatatcaa aatgtttcac caataatagc aatacatttc
     3361 tttaatatac ctcttttatt atatcaaaaa aaacttaatg attatcacac caagctaaga
     3421 gcattgatgg gtaataacat atagcttatc caaccttgtt agcaggagta ttacaaataa
     3481 tgtattgcca agaggaaaag ctgatataaa taggtgggac aaacgtggtc aagaaaacct
     3541 ttaacaccaa gaaaaccatg ataattcttg ataacatcaa atagtgcctc agctaaatga
     3601 ttatgatgac ctttaccaaa tcattcttta ttatctgcaa gaaaagaaca gtgacatctc
     3661 ttcgatccga ttacgaatat aaatcaagct tcaaaaccgc tcttagtacc tttattcgtt
     3721 gccaaaaata tctcattgaa ctctcttatt caaacgctaa gctagaagca accaataaac
     3781 tgagcaaaaa cataaagcgg caagctttgg ctttaggaac ttcaaagcta agattcccaa
     3841 tacttttaac atcacaaaag agagcaccaa gctggtcctc tctagatatt agttattagt
     3901 caccccacta cagttgacat tgagcctctt tgatgacact agtcgtgaat tagtgagaca
     3961 acaacatagc gattagggtc gttgccctct gaatagctct caaccccatc aatagcagaa
     4021 actgttttat gaacaatctt tcgctcgctg ttactcatag gatccatggt ataatcttga
     4081 ccagactcaa gcacacgctt ggataccttt ttggtaaagt caatcagggt ttctgtccga
     4141 tgctctacat aatcatgaac attcaaggag acagaaaaat tcttagaata gcggtcatgt
     4201 aagaaatttt gggccagcaa ttgcagtgat ttcaaaacct taccatgata gccaataaca
     4261 cgacctgcct ctggtgtctc tatctgaaga ttgatctgac gacgattgtt ggtcctctca
     4321 atagaggctt caatatccat ctcatagata atcttggtca catagtcaga aatctcctgt
     4381 gcagctagct caatatcctt actcatgtcc gctgcagctg gatccagctg actcgcacca
     4441 gcagctgacg acacaggctg tgcctttgac tgagtaggag ctgactgagc tgtgcttaat
     4501 ggacctgttg gctgatgagc atcagactca gcagcccttc tgtcttgtga tcgaacagcc
     4561 ttcatctcct caagctccac ctcatcgggg ttaataaccg gtgcattttg acggttgatc
     4621 tcctctggaa cactacgtac ggctttttta tcagccttat agactgtttt ttcattaatg
     4681 ccttcaatat caacctgagc tggcttttta ccaaagccca aaaagccctt tttctccttt
     4741 gaaatcacct tgatgtgtgc ttttagacgt gacaacccca actcttgaag tcctttttca
     4801 attgcttctt caacagtctt acctgtaaac aataccatat cctaaactcc tattttcttt
     4861 tcattgctct cttacgagcg cgacgttcct tagctcgacg ctctttttct tcatctgcta
     4921 aacgttgcct ttcggcaata accttaaagg gattattaaa cagcaagagc tgaacaacct
     4981 gaaaggcatt ggaaactgcc caataaagca ccacaccact ggccagatta aagcccataa
     5041 agaagatgaa cacaggcatc acgtaggtca tgatcgttat catggccgtc ttttctctag
     5101 ccgctagatt ggttagccat gttgataaaa aggtaaagac agccgctaaa ataggcagaa
     5161 taaagagatg atcatgtcgc gccagctcaa cccataaaaa ggtgccttct cttaagaaag
     5221 ccacacgagt cagagactga aacaaggcaa acatcaccgg catctgaatc agcaagggca
     5281 aaaggctcat gtaaggattg acaccatact ttttgtacag agcttgactt tcttcagcta
     5341 gcttcatacg agttgctgtg tctttagcag catatttttt ttgcagggcc tttagctctg
     5401 gttgaatgtc ctgcattttc tgccctgact tgatttgcat gttaaacaat ggcagtaaaa
     5461 gcaagcgaat cattatcgta aataggataa tcccaatccc agtcgatcca tcaaaggaca
     5521 accattggat cgccttggca aaaaaataaa ccaattgctc ccagctacta gatgattgtg
     5581 ctgtcacctc tccacgccca caggctacta gtagcaagac aagcggcact agggctgctg
     5641 ttttaactct ttttttcaat ctcaaaacct tcctcaagca attttgctag ctttaaaaca
     5701 tgatgtaaat tttgtttgac tgcttgataa tctaattcct ctgcacctct cctagcaata
     5761 acaacgaaat cctcagactt gaggtgatca cccagctcca ttaaaacatg tcgtatcttg
     5821 cgctttaccg catttcgagt aacagcattt cctagctttt tgccaacaga aatccctgct
     5881 cgaaaatgct tgtgctcccc tttcaaatgg taaatgacaa attttcgatt tgccatgctc
     5941 tgaccaagct taaaaatcgc ctggaaatct ttctctcgct tgacacgata gcttttcttc
     6001 aaaacttaac tcccatatct aaattattac cattatacca taaaacatta aaaagcctca
     6061 acccttatca atgggcctat aataagagat tggacccact atctaaagga tcagaacaaa
     6121 aaatgctttt agtgaatcac ggtagctgtc aagtcttgat agccttatca atcatactag
     6181 caaagaaaca aaaaaataaa gcccggtaaa ccgagcttta tctccgctga cttgagcatc
     6241 agcaaatatg atatccaaac aaagacaact gaaacaatca ttttaataac aagcagccat
     6301 atcaaaaata ctatttgttt atggagagag agagaaaaca atattttgat tgaattgggg
     6361 atggaccact ccattaccta atgatttcgt aaatctttat tcatactaga cattatagcg
     6421 aaaaatcact aaaaaagatg acaatttcct gaaatgttca tttttcgtcc taaaatgtca
     6481 ttcaacttaa tttttagcga aaagacttcc acttttcaaa aagctgtttc attctcaaac
     6541 gagagaccat acaagaatca ccattttcaa aatacaccaa ttgcttagcc ttatcaattc
     6601 gaacaacatt gtcaagattg accaagtaag aacggtggca taaaaacagc ttaggagcta
     6661 ccgcatgaat ctcagataag ttcccataaa attctaagcg ctctgtttgc gtccacaggc
     6721 acaccttgtg aggcgttgtt gcagttgcaa aataaagaat gtccttataa ggcagcttta
     6781 ggcgggtctg cggggtctca aacaaaaaca tctcttctac ttgacgactc gacatcatct
     6841 cataggtgta gcgaatacat tcctcaatgc gctctttaaa ttgctgacta tcaaccgctt
     6901 tatcaataaa atccaaggca gacaccttgt acctaaagga aataggggcg aactctgaat
     6961 gcgtcgtgac aaaaacaagc acagcattgg gatccttctg gcgaatatct gaggctagct
     7021 ctagcccact tcttgatttg tcaccaattt caatatctaa aaaatacagc tgatgatctc
     7081 ctctctcctg aatgctatca aacagctttt gaggatttga aaacacctct aattgattat
     7141 gaggaatcct accctcttct aatatggacg ccacaatggc ctcaatacga ctttgttgaa
     7201 tcagattgtc ttccagaata aaaatgttta gcatggctta tctcatttct aacaattgtc
     7261 tcaaacggta gtgatcactt ttggttgaaa aggtgatgtg gggatagcgc tctaacacag
     7321 ccgagaactg tagcaggcgc ttatgagcat ggcttcctag ctccaatcgg ctagcatcaa
     7381 attgcttggc aatatcaacc cgcttgagcc ttgtactatt ttcaatgata aaaaatcgct
     7441 tgccatcttg attaaaatag gcaatggata aaaaaggacg agagctgcct ttagctgaca
     7501 aaatagcatt atcaataact accttgaaaa gaacgatgac atctaacagc ctgacagaag
     7561 agctagcaag cgtttcagga atatcgatgt aaacagcaat gccctgcagc tttgcttcta
     7621 atagcttggc atgcaatagg ctgcgaatca ccgaatcctg aacattatca agggctgata
     7681 attcaggtgt tagctgcctg atagagcttg ctgattcttg gataactgtt tgatagacct
     7741 tagaaatagc agctatatct ccactatcaa tactatcctt tagactaatt agaatatttt
     7801 ctgaatcatg cttaatagcc ctgatctcac gacaaagccg ctcaatatac tgattgtgct
     7861 tttcaaggta agcaacacgc tccttttgtg ccagagccaa tctttgagat agctgatcct
     7921 tagcaaagcg gtccagcttg acaatgaccc agatgagcag catgaggtaa agaaaaatca
     7981 tgacagagcg gtaacgaaaa taaatcttga aaaaatctcc ttggatattg atcatgcagt
     8041 gaaccatcac atagtagaaa agtaaggctg cattcatcca aaagacccac ttctttagct
     8101 tgtcctcact gataaactta atcaaggtca aatcaacgct aaaaatatag ctaaacaggt
     8161 aaaaggccgg caaaaccaat gcatgacaga ccatcaatag acctatgtca ttattgattt
     8221 gatgaatgct gtagcctaaa accgctggca aaaggaaaga gccaataata cgaaagagca
     8281 gctcaacaat cataatcgca aacaagccat taaacagatg ctcagaagcc tttttatgag
     8341 gtgcaaagcc aacactgaca gcaacaaaca ccagctgatc aactagcagc acatgatcca
     8401 gcagcagatt agcaacaaca aagcaggcac caaccaaaag caatgatcta acagctagct
     8461 taatgcctga aaatgtcgaa aagatgaccc agctattcac aaagatcaga gcataaaaga
     8521 atgacatacc tagcataaaa taaaactcta ctctttctct atttttggca tgattagggt
     8581 ctgactaaac tgataatcat gactcctggt gcgcaaggat agctcaggat atttctgcaa
     8641 aatccgcttg gcattagaca agcctatccc tcgaccgctc ccctttgagg aatagccctc
     8701 ttcaaaaatc ctactaatca tgaccctttc gtccttggtc gtattggtta cggtgaaaat
     8761 ctgctgatca tcagataaaa agtaggctat cgccactgct ggctgggctg tctctagagc
     8821 agcctcaata gcattgtcac aaaaaataga tacaagcagc aataaatcaa gctctgagat
     8881 atagctatcc cgaatccgat ctggaacttc taggcttaag gcgattcctg ccttctcagc
     8941 cttaatgatt tttgatgata gcaagctttt tatcgaggat acactgattt tactgagctt
     9001 tgaaatattg taatgcttat cgtcccaata atccgtcgcc tcatctaccg tttgggcata
     9061 gacagtctgt acatctgaca cagagccaga gtcaatagcc tgccccagcc tttctagcct
     9121 cttgaggtaa actagctgaa ataccttaac acccttataa agcttttcta gatgctttcc
     9181 ataggtttcc agattagcaa tataagcctg ctgttccttt tttaattcct gttttaagaa
     9241 ttcctttgat tgatgattaa aataagacag taaataaatc aacaataggg taaagatgag
     9301 aaacagcacc ttataagacg ttgacatcat tatcggggat ttaaggtcaa gaaagggatc
     9361 agtaaatcct aaaatcataa agagatcaat atagtaggcc aaactaaaga gcaaaaacaa
     9421 gctataaaag ctactggcct tatcaaacct gtcagcttta acaatctgct tgtaatcctt
     9481 tcccacaaaa taattaatca aagcaaagct tgggaaaatc atcacataag caataaagtc
     9541 taggacaagg tgtctgacat agctgccatt aactgaaaaa atatagggaa gtacaatcgc
     9601 taaaataaag cgtgataaca aatcaacaaa cactccggga acaaaggcca agaatagagc
     9661 ctttaagcta aagcagggcc gcttttctaa ggctaataca gctagcagca ataaaggatc
     9721 aattatcaag ggcggcaata aagcaaactg attcaaaaag agagctgctg tcaggacaaa
     9781 aatctgcttc caaagtgcca gtttaatgtc tgataaaaag gaaaaaatac taatttctgt
     9841 cacataataa atcatcagtg atagtaataa aaagagataa taaatatcag tcattctgcc
     9901 tccttaccaa ctttattatt ttaacacact ttgtgtcaat ccctattata tgaatttttt
     9961 atataattca gcaagcgcaa aaacagtcca tagctggttt gtgacagcgt ttgcaaatca
    10021 gatgtcaatc attaaagcaa attaaaatat ctgaccagcc ttaccttatc tagggaaaaa
    10081 tattgtataa caaataatct aagaaaacca gtgacaattt aatatttatt ttaataatat
    10141 cttccacgct catcaaaaat taagcagata agcctgctgg attatgacat ctagctatgc
    10201 gctactgggc gtcgtgtcgc tagctcaagc acactaaaaa agaatgaagc aaacatcaga
    10261 tatctcatct ctgcttcatt catgatgtta tttatgatca tcgtccagcc tagaccaaac
    10321 tactagctgc gatagtgttt aaagcatatt ggcaatatgc tcaatcgatt gttcacgtcc
    10381 aaggaggtaa atggtatttg gcagctctgg gccatgcatt tctccagaaa cagcaatacg
    10441 aattggcata aagaggttct tgcccttaat gccggtttct ttttggacag ccttgatttg
    10501 tgggaaaatg ttttctggct taaagtcctc atctgacatc gcctctagct tttccttgaa
    10561 ggccttcaga actgttggaa cagtctcagc tgccatcact tctttttctt ttgcggtcag
    10621 ctctgggaaa tctgagaaaa ataaatcagt caatggaaca atctcatcag cagagcttaa
    10681 ttgaggctga tagagctcaa ctagcttctc tgctttttca gtcaagcggc ctgctgcttc
    10741 aagaaatggc ttacaaagcg catatacagc gccaagatca gcatgcttaa agtactcatt
    10801 gctcatccag tccatttttt tctgatcaaa ggctgctggc gacttgctaa gacgaatctc
    10861 atcaaataag gcaatcaatt gctcacgaga aaagatctca gcctccccgc caggattcca
    10921 gcctaaaagg gcaataaaat taaagactgc ctctggcata tagccttttt tgcggtaatc
    10981 ctcaataaac tgcagggtat tggtatcacg ctttgatagc tttttacctg tctcagaatt
    11041 aatgataagg gtcatatgac caaagacggg tgcttcccag ccaagcgcct cgtaaaccat
    11101 caactgcttt ggcgtattgg caatatggtc atctccgcgg ataacgtgtg agatttgcat
    11161 atcgtgatca tcaataacaa cagcaaaatt gtaggttgga tagccgtctt ttttctggat
    11221 tacccagtca ccaccgacat tgccaccctc aaatacgata tcgcctttta ccatgtctgt
    11281 ccatttgtaa acaccagcct cattgaccgc taaacgaacc gtaggcacaa tacctgctgc
    11341 ttcacgctct gcaatatagg ccgccttttc atatgctgac atgccaaggt attcattgac
    11401 atagcgaggt gtttcaccag ctgcctcttg acgctcacgc tctgctgcca gctcctcctc
    11461 agtcacataa gacttgtaag ccttgccttc tgccaataat tggtcaatgt attgttgata
    11521 aagggctaga cgctctgact gacgataacg ctcgtgcgtc tcaggacttt cgtcccaatc
    11581 tataccaagc cattttaaat tttccagctg agaacgctcg ccgtcctcga catgacgctt
    11641 acgatcagta tcttcaatac gaataataaa gtcaccgcca tgatgacgag cataaagata
    11701 gttaaagagc gctgtccgcg catttccgat atgtaaaagg cctgttgggc ttggtgcata
    11761 gcgcacacga attggtttag acattctttt tctcctatgg tttcattgaa agaagggatc
    11821 ctgggctata aaccgttcct acggtaggct tgctctatga gaaaatggtc gataaggaac
    11881 aaaaatacag ctaatccctt ggaaatctaa agatttcaat cgctcctatt atagcacaac
    11941 ttcaagcatt gggcgacaaa aatcaactta gaacagctgc ataacgaaaa tgcatgtaac
    12001 cattttctag ctacatgcat tgttttcatc tacttctgat attttgatat catcagctgt
    12061 tcacattcag cttaattgta gcctgaattg atttgaaaaa gaccatacca ctgatgagaa
    12121 aatcgctatc aaaaacgtaa agatccttat gcgtttggcg tggcctagag ctaggatagc
    12181 tctataagca gctcattggc aagcagtgct gcctctttca atagcttcat agcatgccta
    12241 gctatagata ttagtcaggc tattgacctg cattgatgtc aagctacacc ccagcaaaga
    12301 aagcgacaat atactctggc aaccacgaac ctgtcatatc catttcaatc catcaattgg
    12361 caaggcttgg tttacttcca actgcttaat ggccgcctgt gacaatatag ctctgtaaaa
    12421 ctccagcaaa ttgctgaagg ttcaggcttt gcacatagac atctccgtat ccgctaaagg
    12481 tattgaccac tccctcacct gtaccaatag actgcataaa gccattttcc aaatgaatat
    12541 cataatccaa atcctgactc caagccacca catggctatt atcaatcgtc atgctgtcgc
    12601 catgaagcgt gattttttta atcgaaccaa aagcattgac caatagggtt ccttctcctt
    12661 gtgttgacat cacaaagaag ccaccctgac cgctaaataa ggccttacca agtttttggc
    12721 gcttcatggt gtagtgagct gagccatcta aagccaagaa ggctccgtca ttcaaacggt
    12781 attgatctac ccctagctca agagcaataa cctgaccagg cattgaaggg gcaagcgcta
    12841 gcttgccact aacatcatta gcaatcgcct gtgtgataaa catggattct cctgaaacca
    12901 ttgaacggcc aatggcacca accagcttgc caagacctga gccacgccca ttgagcttgg
    12961 tgtttaagct gattgacggt gtgtggtaaa ccatactgcc tttttgtaga aagacagact
    13021 cccccatgtc caaatcaatt tcaacaagag gaaactgcat gctgctgtca atagtatagg
    13081 tcattcgatt ataggccata acaccactcc tttgtatgat tttgttgata caatcaagta
    13141 tagtcttttt tggcagcatt gtccactagc tactgtcgcc gccattccta accagtctca
    13201 aagccatact acaaaccgat cagctgtcag gatttcggca tcgccacctg agacatacgt
    13261 ccagtggcaa catcatagac cgcaccacta atgaccacgt cttttggaat caacggtgat
    13321 tgctgcaata tagccatatc ctcacgaaca cttgcttcca catcagtaaa ggggagaaaa
    13381 tcacagtcag acacatctac tcccagagta tcatgaagct gcgctgtaaa ggcttcattg
    13441 gtaaaggttt gcgccccaca atccgtatga tgaagaacaa cgatctcacg cgttcccagc
    13501 tgctgctgcg aaatcacaag agaccgaagc atgtcatctg ttatccgtcc accagcattg
    13561 cgtaaaatat gggcatcacc aagcgctaaa cccaaggcct gcgccacatg cagtcttgag
    13621 tccatacagg tcacaatagc taccttagtt ttgggcttta ggggcaaatg agcagtccca
    13681 tgtaaggcga cataggcttc attggcagat aaaaagcgtt caaaatatga catgaatacg
    13741 gtcctcccag actaatctct aagctatctc agccttgagc tgtctgtcta tcttatcatc
    13801 ttttgcctga aatgtctgaa tgctgaactg ctttttaaca caagcagata gcactagcct
    13861 aactgaaacc agaggtaggt gagccagcct tgacattgga agcaagctta gcagcccgcc
    13921 ctttgagccg ctaaagtaag ggcagcaaga acgtgacaaa atcagttaat tgtcatttta
    13981 attaaaaaac gaaactacgg agacaaactg ataaattgct atttctcgct atcagccagt
    14041 atgctaaact cttctcagaa ggccttggca gtcgctagct gctaagccaa taatactaaa
    14101 ttaaggagaa tagcaatgaa acaaacaaaa ataatctgct tattggctgc tgctgctgtc
    14161 ctaaccctag gtcctatcag cacaggccag acacaaccac agaccgtata tgccagtcag
    14221 gttagtggag acagctgtat cgatctaggt aatggatggt ttaaatgtcc taaggatatt
    14281 ggaggatggg acattctttt taatcaagat taccaagcgc cttcacgatc gccatttttc
    14341 acttggattt caggctggtt taactttata tggcagtggt ttaaaagctt ctaagatcta
    14401 ctaatacgct atccatatca taaggctctt agaggctagc tctctaaggg ctttttggtt
    14461 ctacggaaca ctataaggac cttccaatac tactggtctt aaaataaaaa agactaggaa
    14521 tagctcccct agtcctcatg ttaaaaacaa caacctaagt aaagacagcc tttaagacct
    14581 ctcctactgt cgtcacacca acaacctcaa tcccttttgg cagatcaatc ccctgcaatg
    14641 agcttttcgg agcgtaaagc ttggtaaagc caagcttagc ggcttcatta atccgctgct
    14701 caatacgggt cacacgccga atatcaccag tcaagccaat ctctcctaaa aaggcctcct
    14761 gagggttggt tggtttttcc ttgtagctag aggcaatggc cacagcaact gccaagtcaa
    14821 tagcaggctc atctagcttc acaccgcctg ctgacttgag gtaggcatct tgattttgta
    14881 gcagcagccc acatcgcttt tccaagacag ccataatcag actgacgcga ttaaagtcca
    14941 acccagttgt cgttcgtcta gcattaccaa aaacagtcgg tgtcaccaag gcctgcacct
    15001 cagctaaaat cggtctgctc ccctccatgg tgacaaccac agcagagcct gttgcgccgt
    15061 ctaatcgttc ctctaagaac acctgactgg gattgaggac ctccactagc ccacctgatt
    15121 gcatgtcaaa aataccaatc tcattggttg agccaaaacg atttttaacc gctcgcaaga
    15181 tacgaaaggt atgatgcctc tcaccctcaa aataaaggac cgtatcaacc atatgctcca
    15241 gcatgcgagg ccctgctagg gtgccctcct tggtgacatg tcctacaata aaggttgcaa
    15301 tatgattaga cttagctagc tggagcagct cagcagtgac ctctcgaacc tgactgaccg
    15361 agccctgaac acccgaaatc tccggactca tgatcgtctg aatagaatca ataatcaaaa
    15421 aatccggctg aatggcttca atctctgctc gaatagcctg catattggtc tccgcataga
    15481 ggtaaaaatc attgtcggtc tgtcccaaac gatcactgcg catcttgatc tgctctgccg
    15541 attcctctcc agagacatat aaaacagttc ccttatccgc aagctggata gaaacctgca
    15601 agagcagcgt tgacttacca ataccaggat caccaccaat caaaaccaag ctccccggca
    15661 caacaccacc gcccagcaca cgattgaact cattcatctc tgtctggata cgctggtagc
    15721 gaacgccatt gatatgcttt agcttgatgg gcttactttt ttctccagtc aggctaatac
    15781 gggcattttt gacgtccttg acctctgtct cctctacaaa ggaagaccag gcagagcaat
    15841 tagggcagcg ccccagatat ttgggtgact gatagccaca ttctccacag ataaacctcg
    15901 cctttttctt agctataaca catttcctcc ttgaatctaa gcatcaactg gctacaagca
    15961 cgtgaagcag cctgctaata ccttatcctc ctgtcgaacc aaaaccacct gtccgctcac
    16021 caccagcctg atcaccatca gcaatcaaaa aaggcataaa tacgccctga acaatgcgct
    16081 caccagctga caaggtaatg gtttgatccg taatattttt catctgagca aaaatatgcc
    16141 cttcattcgc agggttacca tagtagtcac catcaataac acccacagaa ttgatcagaa
    16201 ccagtccctt tttacgagga ttgctggagc gatcatagag ataaagcacc tcaccgtctt
    16261 gcatatacgc cttgacccct gttggcacaa gtacaatctc acctggtgca atgctggtct
    16321 cctctgcaac agataagtca tagcctgctg catgagctgt ctcacgtttt ggtaataaat
    16381 cagtatcagt aaagcctgac acaagctcaa agcctcgaat ccttgtcatg attaacctca
    16441 agagcccttg tcagtgcctg cagcagctgt aaaatcacct gccaggacag cagacaaaag
    16501 cactcttatc ccttttcttt ttttagtcct cttattataa aatattcgta aaggaatagc
    16561 aaaaaagtag gggctgcacc ccaaaaatca ccgactgccc ccctctataa cgcaacaaaa
    16621 tgcaagaggg ctaaatctcc ttgccggcat agctaaaccg aatccttgga aaatcagcct
    16681 ccaaatcctt atctgccata aaagccttgg cgtccttttt cacctgaacc agatcaatcc
    16741 cttgtatgtt tgcagcatag acgcagccgc aatagcactg gcggtaaata tcatattcct
    16801 cacacatttc gaccgacctg cgatagccat tatttttctt gaaatcacta ggcaaatact
    16861 tagtggtgta aaccttttgc acatcaatgc ctacatcgtt aatcgtctgt gagtttttat
    16921 gagggctgat ggtcaaggca ctagcaaaat aatcaaagcc cagctccaca gccttttgtg
    16981 ccgtcttgtc caagcgataa tcaaagcaaa cacgacaacg atccccgccc tcagactctt
    17041 tctccaagcc tcggacagtc ttgacaaatt catttggcac ataatctgcc tcgataaact
    17101 gcacgctatt acctgtttta tcgttgaact ctgctacaaa tttctgagta acataggccc
    17161 tgcggtggta ttcgtccttt gggtgaatat ttgaattagc aaaataaacc gtaatatcag
    17221 cgtactgggt taaatattcc agcgtgtagg ttgagcaggg agcacagcaa acatgcatca
    17281 aaatgcgagg acgtatagac tccctcgccc agaccttggt catctgctgc atgacccgat
    17341 catagtttat tttctggttt ggattcattc tagctagaat ctcttgtaag tcaatcatta
    17401 catcttctac cttctattgt ctgtctcttt tattatagca cattgccttg acatgctttg
    17461 catcaaaaaa ctccgccaaa gcggagtcga tcggcaaaag ctgttttgat ggtttttaag
    17521 aataacaaca gcagcttatg taatgatcat ttttagaagc tactcaaaca caaactgatt
    17581 gtgataaagc tcggcataaa agcccttttg ccttagcagc tcatggtgac ttccctgctc
    17641 aataacctta ccgtccttta gaacgatgat ttcatcagca tttaaaatgg tttttaggcg
    17701 gtgggcaatc acgaagcttg tgcgacctgc cacgatagcc tccatagcct tttgaatctt
    17761 actttcagta acagtatcaa catttgatgt tgcctcgtcc aaaatcaaga cctgaggatc
    17821 ggttaacagc gtacgagcaa ttgaaataag ctgcttttga ccagttgaaa agacattctc
    17881 atcatctgac acctgagttt ggtagccatc aggcaaggac atgataaact catgaatatg
    17941 cgttgcacgc gctgctgtct caacctcttt ttggctgatt gtctgattac caaagcggat
    18001 attatcagca atagtcccag aaaacaagac tgactcctgt aggacaatac caacccgctg
    18061 acgcagacta tccaagtcat attccctaat atcacgacca tcaaaggtaa tagagccagc
    18121 atcaacatca taaaaacgat taatcagatt catgatcgtg gtcttgccag accctgtcgg
    18181 tccaacaaca gcaaccattt tcccctttgg agctgaaatc gacacatctg acagaatttt
    18241 ttgtcccggc agataaccaa agtcaacatg cttaatctca accccttctt ttaatgctgt
    18301 aaagacagga gcatgctcag ggcgaacctc ttctttttca tcgaacattt cttggatacg
    18361 accagcacct gtaaaggcca gctgcaattc accccagcta gaggcaatct gcataatcgg
    18421 ttgataatac tgctgtgaat actgaacaaa ggtcaccacc aagccaagag cagcagctgt
    18481 tgacatggac ttgtcaccaa ggacaatggt tgagccagca aagatgacaa tagctgtatt
    18541 caaaagactc atcccattca tcacaggaaa cagcagacca gcaaaaaggc gtcccttaaa
    18601 ggttgctgca cgcaccctct cattgtgctc aataaagcca tcaatagcat cctgttgcac
    18661 cccttgaaca ataatagcct tctggccaga aatcttctcg tccatgtaag catttaaagc
    18721 actgacctcc ttttgctgca aatcagtata tttgcgggcc attgtaatga tgacaacgag
    18781 aagaataagc gccacagggg ttgaggctat cgttaccaag gccaagcgac tatcctgcct
    18841 aaacatcatc agcactagac caatatacaa agcaatattt gtcaagacct gaatcagaga
    18901 ttggttcatg gagttttgaa tattatcaag atcactggta aagcgtgata gaatagcacc
    18961 gtccttgtga ctatcaaaaa agccaactgt caagcgctcc aatttgccaa ataagccctt
    19021 acgcatgcga ttggtcgaat gcgaaataac ccttgtaaag aggagactat aaataagatt
    19081 agccactgct gtaaagagat aagccaacaa tagctttccc ataaccgtcc taaaaggcgc
    19141 catagagggc tcaactaagg gctgacccgt cattttgcta agcgcctgag ccttgtaata
    19201 gcgctgcacc cattctccca gctcagctag agagtctccc aaaaagacag gggccttaac
    19261 ctgcaggtag gttgccagga caatagcaaa gaatatcaca acaaaagaga gcttataacg
    19321 tttaaaataa aaccagaaaa atcgcaggat cttcattagt tctcctctct tcccttttga
    19381 gtttcgtaaa tttcacgata aatcggattg gaagcaacca gctcagcatg cgtcccttct
    19441 ccaatcaatc gaccattatc aagaacaaga atcttatctg ccttgacaac tgacgatatt
    19501 ttttgtgcga tgatgactgt tgttgtctct ttgagctcct tattcaaggc ctcctgaaca
    19561 agcttttcag atttggcatc tagagctgat gtcgaatcat caagcaccaa aatcttagga
    19621 ttgttaatca caccacgagc aattgacatt ctctgctttt gaccgccaga aaaattattg
    19681 ccacgctctt ctacctcact ctggtagcca gcgtccatac ggtcgataaa ttccttggcc
    19741 tgcgcaatgc gtgctgcatt ttctaaagcc aattggtcag catagggatt gccctgacgc
    19801 agattatccg caatagtccc agaaaaaaga atagcctttt gcagcacaat agagacggtg
    19861 tcgcgcagag tctcttgact gatgcttggc agagccttac caccaatcag gatttgccct
    19921 tcctgtgggt caaacaaacg cggaatcagc tgcgcaaggg tcgacttgcc agcacctgtc
    19981 gcaccgacaa taccaaccat ttgaccgggc tcaacctcaa acgaaatatg ctttagagtg
    20041 gcttcactgt catttggata ggtaaagctc acatcatcaa agacaatact gcctgtcagc
    20101 tcctcctgct catggttaac aaaggtcata gcaggctctg tttctaaaat ctccctgatc
    20161 cgaccaatcg aggtcaaggc acgacttgcc tgcattccca taaaaccaac catcgtgatc
    20221 gcaaagctga tttgtcccat ataggtcata aaggaagcca tatttccaat aacagcagga
    20281 tctgttttga ccagccctga aaccagatac aaggacaaat aaatggccat gtaagacacc
    20341 aacatcaaaa taggctgcat gattgaaaag ccatagccga taaacaaatt caagcccagt
    20401 aggtcatttg aagcctcctt aaatgtgtca tactggcttt tttcctgaac aaaggacttg
    20461 accacacgca caccgcgtag gttttcctta gcaatctgat tgatcctatc catcaagcgc
    20521 tggaagatcc caaagcgagg acccatctgg ctcatcacca gcccaatgac taccattgtc
    20581 atcacaacca caagcaccaa gacccaccaa aggctcggta aggcctgcac cgctaaaata
    20641 aaggcaccga caaataaaat cggcaagcgc aacaatatct gaaaaagcat catcacaaag
    20701 ttttggattt gattaatatc atttgtcatt ctaacgacaa gatttccagc attgaaggct
    20761 tccacattgg cataagaaaa ggattggatc tttctaaagg tctgctcacg aatatcagca
    20821 gatacccctt gagcaatctt ggcagacaag atggtattga ccgcacctga caccaagcca
    20881 atccctgcta tcactaacag ccaaaaaccc acctctgcaa tccttgtctg atcattttcc
    20941 ataatagcag ctagaacatc tttgaggtaa tgtggctgga gcagggcact ggctacgacc
    21001 ccagaaatca tcactaggga cagagccgca taccatttat acttcatcac agcatttcta
    21061 agcatctgta tctcctttat aagctcgtat attttgtttc agctgatcga taaccttttt
    21121 taccgtcagc agctcttctc ttgaaatttc cttgaaaaaa tagcgctcaa tatctctgcg
    21181 gcactccttt aataccggca gcttagccct accagccgag gtcaagacaa cctgcttgca
    21241 gcgcttatct gtagccgagg caacaactcg aataaagcca tttttttcca tacgcttcac
    21301 cagattactc gtaaccgatt ttgagatttg aagctccttt tcaatgtcct tgacaaaaat
    21361 gtctctgtct tgatggcaat gcaaaaagac aagaacatgc ccttgtggac cagcaagatg
    21421 ctggaggtca tactttttag caatctcttc gctaatttgc tcaacctgat gggtcaattc
    21481 acgaagctca gcaatgattc ttggcatttc cttcctcctt agttctcatg ataaccattt
    21541 tagttctctt gggaactatt gtcaaccaaa aaggcttacg atctgactat cttccctgct
    21601 acttaccctt tgctagcacc actgagctga caggctaggc cagcagacct tttctattag
    21661 agttaggcct tgtcttatga tataataagg tgattagctc ttaaaggaga ataaaaatgc
    21721 caaaacaaaa ggtagccatt ttgggacctg gctcttgggg cacagccctg gcacaggtcc
    21781 taaatgacaa cggacatgag gtccgactat ggggaaatat ccctgaacaa atcaacgaaa
    21841 tcaacacacg ccatactaat agtcattatt ttaaggacat tgtcctagat gaagccatca
    21901 aggcaaccct tgatttgaag gaagcattgg ctgatattga tgctatattg tttgttgtgc
    21961 ctaccaaggt gactcggctt gttgccaagc aggtcgctca ggtcctagac cacaaggcta
    22021 ttgtcatgca cgcctcaaag ggattagagc ctggaaccca tgagcgcctc tcaacgatcc
    22081 tcgaagagga gatccctgcc cagctgcgca gtgaggtcgt ggttgtgtct gggcctagcc
    22141 atgccgagga gaccatcgtt cgtgacatta ccctaatcac tgcagcctca aaggacatca
    22201 cagctgctag gtatgttcag accctcttta gcaaccacta cttccgtctc tacaccaata
    22261 ctgatgtgat cggtgttgaa accgctggcg ctctcaagaa catcattgct gttggagccg
    22321 gtgctctgca tggccttggc tatggtgaca atgccaaggc tgctgtcatc acacgcggtc
    22381 ttgcggaaat cacacgacta ggggtcaagc ttggggcaga ccctctgacc tatagcggcc
    22441 tatctggtgt tggtgatttg attgtcacag gaacatctgt gcattcacgc aactggcgag
    22501 ctggtgctgc tcttggtcgc ggcgaaaagc tcaaggacat cgaaaacaat atgggcatgg
    22561 tgattgaagg catttccaca accaaggtag cctacgaaat tgcccaagag ctaggggttt
    22621 atatgccaat taccagcgcg atttacaaat ctatctatga aggtgctgac attaaagaaa
    22681 gcattctggg catgatgtca aatgaatttc gctcagaaaa tgaatggcac acataaggaa
    22741 ccacaaatca aggaggaact catgacaaag gtcagaaaag ccattatccc a
//
LOCUS       DARYLD010000033        22791 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYLD010000033 DARYLD010000000
VERSION     DARYLD010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22791
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(93..563)
                     /locus_tag="TU651_001165"
     CDS             complement(93..563)
                     /locus_tag="TU651_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL0897174.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            784..1634
                     /locus_tag="TU651_001166"
                     /pseudo
     CDS             784..1634
                     /locus_tag="TU651_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1970..2260
                     /locus_tag="TU651_001167"
     CDS             1970..2260
                     /locus_tag="TU651_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL0897175.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2274..3413
                     /locus_tag="TU651_001168"
     CDS             2274..3413
                     /locus_tag="TU651_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897176.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3410..3892
                     /locus_tag="TU651_001169"
     CDS             3410..3892
                     /locus_tag="TU651_001169"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL0897177.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3889..4476
                     /locus_tag="TU651_001170"
     CDS             3889..4476
                     /locus_tag="TU651_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0897178.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4473..4955
                     /locus_tag="TU651_001171"
     CDS             4473..4955
                     /locus_tag="TU651_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897179.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4980..5495
                     /locus_tag="TU651_001172"
     CDS             4980..5495
                     /locus_tag="TU651_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897180.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6129..7763
                     /locus_tag="TU651_001173"
     CDS             6129..7763
                     /locus_tag="TU651_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897181.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7904..8797)
                     /locus_tag="TU651_001174"
     CDS             complement(7904..8797)
                     /locus_tag="TU651_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL0897182.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8781..8972)
                     /locus_tag="TU651_001175"
     CDS             complement(8781..8972)
                     /locus_tag="TU651_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897183.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9207..10961
                     /locus_tag="TU651_001176"
     CDS             9207..10961
                     /locus_tag="TU651_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL0897184.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11102..11482
                     /locus_tag="TU651_001177"
     CDS             11102..11482
                     /locus_tag="TU651_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL0897185.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11520..13853
                     /locus_tag="TU651_001178"
     CDS             11520..13853
                     /locus_tag="TU651_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0897186.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13902..14054
                     /gene="rpmG"
                     /locus_tag="TU651_001179"
     CDS             13902..14054
                     /gene="rpmG"
                     /locus_tag="TU651_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL0897187.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14066..14242
                     /gene="secE"
                     /locus_tag="TU651_001180"
     CDS             14066..14242
                     /gene="secE"
                     /locus_tag="TU651_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL0897188.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14633..15178
                     /gene="nusG"
                     /locus_tag="TU651_001181"
     CDS             14633..15178
                     /gene="nusG"
                     /locus_tag="TU651_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL0897189.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
     gene            16221..17738
                     /locus_tag="TU651_001182"
     CDS             16221..17738
                     /locus_tag="TU651_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0897190.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
     gene            18020..18883
                     /locus_tag="TU651_001183"
                     /pseudo
     CDS             18020..18883
                     /locus_tag="TU651_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            19472..21973
                     /locus_tag="TU651_001184"
     CDS             19472..21973
                     /locus_tag="TU651_001184"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL0897191.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            22160..22651
                     /locus_tag="TU651_001185"
     CDS             22160..22651
                     /locus_tag="TU651_001185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897192.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYFDEGYSARQGINDLKS
                     LEN"
BASE COUNT         6707 a         4143 c         5057 g         6884 t
ORIGIN      
        1 atcaaggctt ttgcaggaga tttatgaaaa agaaaaattt aggatagtgt aagtataagc
       61 tagtttcctt aagaaaagct taactgaagc aattaatcgt agagatgggt gattgttttg
      121 acgacttttt tctccttgtc agaccaataa tgaaggcgtt caaaagatcc ttgtcgccag
      181 tagagtggta gcctttgtcg aatatcctct tgcatgtcta gcttatctag atcagcaata
      241 gcatgccatt gtggtaggcc ctctcgtgat ttagttagca gcttgccttc aaaatcttcg
      301 caaagaaagt cataataaac atagcgctca ggcttatcag gattggtaaa gcctgagatt
      361 ccctttaatt gcagatttaa ggcggttaag ccggtctcct cctttagctc acgcactgcc
      421 gcttcaaaaa aggattctga ggtgttaacc ttgccacccg gttggatcca gccaggaaaa
      481 tcgtcatgct ggcggttgag aagtaggatc ttgtcgccct ccttgacaca gatattaacc
      541 caatttttga tgacttcaag cattagttac ctcgttttta gttttatttt atcaaaaaaa
      601 gatcagtatg aatagctgag agatttattg atatggtcat aatggcttca gatagtttta
      661 ctgctgcttt agccatctgc ataaataata taaaaatacc atttcacatc attatttaat
      721 agatttatta tcatattaat ggtataatta tgtgaaatta gaactatgtg tagagagagt
      781 ataatgaata gtacagattt gatgagactg ggagagcttt ataaggagct tcgtattgct
      841 cgtggactta ggctaaagga cgttgctaga gacaatttat cagtttcaca gctatctaag
      901 tttgaaaatg gccagagcat gctggcagct gacaaactac tattagctat ttcaggaatc
      961 catatgacat tcgctgaatt tggtcatgct gtaaatgggt ataaagtcag cgattttttt
     1021 cagttaggca ccaaggttgc cgagctacaa acagcatcag atatagatgg attgaaggag
     1081 cttctgagcc aatataaggg tgatgacatt ttttctgttt ataatagatt aaatgaatta
     1141 atcattaaaa gtgctatcta ctcacttgat ccaaatgtta aaattgaaga atcagacaag
     1201 caattgttga cagaatacct ttatagtatt gaagagtgga cggagtatga gctatacatt
     1261 tttggcggtt gtttggctat tttatctgat gaggatatga tttttttggg aaaagcattt
     1321 atcgaacgag ataagatttt cctttctctt ccacaacata gaaaggcagc tcacatcact
     1381 ctcttaaata ttatcatgac aaggcagctt tttatgttga tttttttatt aaaaagctgg
     1441 aggagttgat tatctatcaa gatatgttca ctatagtgag cttaaatttt tttaagaaaa
     1501 tatataccta cttaaatgaa gaaagtaagc ataagagcga cattgaagat tatattaatc
     1561 ttgttaaaca gcttggcaac cctcagtttg cccaaattct acatcggacg ctatcagtga
     1621 ttctagatag ttaatactaa aaaagtagcc caatcgtttg gtggctacag tggccaaggc
     1681 caccaaatag acaaaagggc taataagaaa ataaaagctt ttcgcataat atctcacctc
     1741 cttgataagg atattataca aaggggaagc ttcaatctca aacattcgca aatatgaaaa
     1801 tattaacaaa agcatcatca tatttgcgaa tatcgagaat atgataattg tcgtgatata
     1861 attactgtgt taatgattta gctaggcatt aataaatcta aatatagact acaggcaggt
     1921 cgctcgttat actagtttga gggccaatgg tctgggtagg aggaagcgta tggcgacatt
     1981 agagcgacat cataaaatgt tattattgtc aatggcatta ggggcagcga gctggttagc
     2041 actcggattg attagcttgc caaatcttgc aggtgcttta ggaataagta ctgctaatgc
     2101 caatactaca gttaatttgt tgagtgctta tagtacagtt tctagcgttg ttgcaatcgt
     2161 tggtgctgtt acgggtgtag ggtctattgg agctggaatt gcagctaccg ttttatacct
     2221 tatcaaacaa aaaggaaagg ctgctgctgc tctctggtag ttaattgtct gatatgaagc
     2281 atgttttcaa atatcataaa ggcgacattt tagggtatct caatattgtt gggtttaccc
     2341 ttttgtttta tggctcagtg ataggtatga taatgttcag ggattatttg acctatgatg
     2401 gagctggttc tctaatatcg acctttattc tggtatcagg aacctatcat tctgtgaaat
     2461 caacatttcc atatgaaggg aagcgtcatc caacttttat attaacaccc tattatctat
     2521 ttaagcatct attgctttca gttacaaagg tttatgcttt ccagatccga gtggttacta
     2581 taggaatcat ctgtttagca atagcctttc cggagcagct tgtttggata gccttgtctg
     2641 tgctagcagt atttatatat tggctatcgc ttccgctagt agccattttt cgagtagctg
     2701 gacgactcct gaatcttctc atgatttatg gtatgtatct taatcaggag ctgctggtca
     2761 ttgcttgtct ttgtttaaat gtggttattc ttgtgcttag tgttacgatt aatgtacatt
     2821 atccctacca atggctggcg gtgagagcta ggaaggaaga aaaaacaatt accttgttaa
     2881 agcttgttat caatacgata acagatcatt tagctttaat ggttctgttt agtattttct
     2941 gtatagctgt gacctatttc acgcaaaggc tgctgctaag ttttgattat tctagcttta
     3001 gcataccagt ttttttctta tctgcttcta cctatatcgc gttactagag gttatggtcg
     3061 gtaaaaatat taaggagctt gagttagacc ggggcttggc tgttttacag tttctgaata
     3121 gggatatcag tgtttacaaa gcttatcgca acagccaatt cttgctttct gctcacatct
     3181 tagctgttat tcatacagga tgtgccatag gcttactacc atttttacta aatggtcaag
     3241 ctgctctttt tctgtctaac ctagtgatga tccccttcat ctactttata tcattttgct
     3301 atttcgtgaa atcactaaaa atagttgctg gtgatttgtc agtgtttagg tgggttattc
     3361 tggttttgta ttttatacta gtggtcattg caatggtagg tagtcgttta tgataatgag
     3421 gaaattttta agatattata tcagttttat tattttctca atagcaattg ggattttaat
     3481 cggtttgctg atcaccagtg atactgtcat attatctaag ccagagcggg gctgggattt
     3541 tactctggag gttttgaaga ataatagcaa taattttttg tcctatattt tcctcttctt
     3601 tttgtcccca gccttgcaat tgattgattt ggtatcagtt gttatacaaa ttactctagg
     3661 aatgaggaag tctggatttc taataactgc cttgggtttg tttccgcatg gtttgctgga
     3721 gatccctaat tttctctttt atcaaggctt gagtcaatat atgctatgga ctgttttgac
     3781 tgaaaaaagc atgacgtcct tcttagaaag agaaagaaga tatgtaaggt actatcttat
     3841 atcgtattat gttttgttaa ttgctggtat tatggaaggg ttactcggat gaaaatagta
     3901 aatgaaagca agtcattttc aaacagaaaa atcttaaatc acatatcctt tgactttagt
     3961 aaagggctgt ataaggttga agggaataat ggtagtggta aaaccacttt tttgcgcttg
     4021 ttagcaggct tagaacggtt tgatagcggc catcgcttac agcataaggg agatattcta
     4081 tatcttgata ctaatgctat cggtgtagtt cccttaacta ttgaagacaa tctgacatta
     4141 ttatggaaaa cctttaatgc ctctcctgat gaggagacct tgtctgtgat taatcagttc
     4201 tttggagaac ggttactaga tcattatctg acggcttctg taggaacaaa ggctaaggtg
     4261 ggcttatcct tgctttttgt aaaggattgg gattatattt tcatagacga agccctatca
     4321 acgcttgatg ggtttagtct tgatatggtt gcaggaagat tattagcatt aaaagaaaag
     4381 gctactgttt tttacgtttc tcataatcta tcacaccagc agctattgtc agaatcacag
     4441 gtgatttatc ttaatggaaa aggagaaatc tattgaaagg taatcctttt aatcgtaatc
     4501 tttcttggtt aatagcctat gtgctattac tttcttgtta tgtattcata ttagtagatg
     4561 gtggtttttt aaaaaacagc gttcaagaat tggaagtcct gctcggccaa acatcactag
     4621 ctataaagct gtttttgatg gtgatatcaa tagcttttag catcatatct ttactggttg
     4681 agtatttttt aagcaaattt ttagtgctgc tttttattga agctggcatc gtttctttaa
     4741 atgatgttct tactgctaaa tcagtgactt tagtgatcca tttatctgct ttgctattga
     4801 agctatctcc ctctccactt tttcagtttg tagtgaatgc tttagggatt gtgatcatgt
     4861 atggattgag tatcaagaga caaggaaata ggacaactgc tcttttgttt tgtttaccct
     4921 ttacactgga tattctagca acattgttgc tttagtgatt ttgagttgga ggaaaagtaa
     4981 tgaaaaaaat cttatattta tcagtacttt taggaacgtc aattctagca acattgatta
     5041 aaatttataa cacttttttt gcaaagctaa aggcttcatc aggtcattca actgggaata
     5101 tagagattga tgccctttta tctgagtcta gactagtgtt ggaaaggcag catgccttca
     5161 caacaaatgg aatcaacaag ctattcgtta tgatgatgag tctaatgctg ttattagcct
     5221 tatactatct gataaaaaag gatttgaagg ccgtctatag ttatttgctt tacctggtgt
     5281 taaccttggt tcatgcaatt tatagcttct tttcgttaag tcccttggca aagctttatt
     5341 ctgatgatat gctgggggct acaatccaga cgggagagaa agctaaattg attttttcag
     5401 tggttctttt tcttctttat ctgcttattg ttgtggccaa taatagagta aaatctagtg
     5461 tagaacccgc ttcatctatt gggatagatg tgtaatacct ttcatattat gacctttaaa
     5521 gccttttagc ttctctaatt ttcagagtaa ctaggaggct gtttgtgacg ctctgagcgt
     5581 tttttcgttt ctatcaaagt ttagctgcgt taatgctatc tatttccgta gctgagatac
     5641 aagatattat aatatgtgtt gtcataccat aaaaacacct tacaggatat tttatgatca
     5701 atcctccttg aattaagctt tctttaagca agggtgtgta tactagccgt aatcctaaat
     5761 aattggttac ctaatgataa ctaatttttt cataacctcc ttcctaaaaa cgatgtcagg
     5821 gcagtcagga ttgattgctg ttatggcatc gtttttgttg tactttgata ggggatctag
     5881 ctgtatgtta aatagcctat caggattgag tggcgaagat gatcaggagt ctcttggctc
     5941 taggttatgc tgctgtttca tgagaaacag ctcttgatga tcaatttagg tagtattagt
     6001 ggtggtcatc ttagcctttt aggctttgag ctgctttatg tttgctcatt tttaatatgt
     6061 tagtgtttac acaaataatt ctcatttttt gatataatag aaaaggtaag gaagggtagg
     6121 agataaggat gacaagattt tttcaaaaaa aacaggccaa aagcttagcc attggttttg
     6181 tgagcttgtt tgctgtgctc attgggtatg gagcttttca ctattctaag gccagtcgta
     6241 tcaatgccta tctacaagca aggtcatcag gctctgggca ggtgcttgaa aatatcaagg
     6301 aatacctcgt gtgggcagat accaatgagc agctgaccaa tgatcaagca agatacacca
     6361 gctttaagag atacagtaag gcagagctag taagcaagcg tcagcagctg caaacagcaa
     6421 ctgcagctga tgatatgtat gtcaaatcgg ttggtcgcaa atttttgatt ttccctgatt
     6481 atcgcatagc agtgaagcct gtagccttga caatcaagac caatgtgcca aatgttgata
     6541 tcttgttgaa ccataaaaag attgctgtat cacagtcaga ggattttagc acaactattg
     6601 aaagactgcc ggctgctgat tataaggcga gtattaatgg ctattataag gatcgtaaga
     6661 ttaaagtcag caaggcctat gatggcaaga accatacact agatttgagg gttaccttta
     6721 agacatttac ggtaaccagc aatgtcagag atggcgagct ttatattgat ggcgagcgcg
     6781 tggaaacttt gaaggctggg cagcttcagc tggaagaata ccctgtgaca gaaatcgcaa
     6841 aggcctatat taaaaagacc tttcctgatg gcgagctaac ctccagcaag cattcccttg
     6901 ctcctgttgc tgagggctcc cagctagaga ttaacattga tcacctcttg actgaggaac
     6961 aggcgggaca ggtgttggtg gcagcctttg atcaattgct cacctatctc aatcaagggc
     7021 aggatccagc aggtctttca actgtttttg agcaaggggc taataatgct ttttacaaag
     7081 gcttgaagga ttccatcaaa gcaaaatttc aaactgatac cagaaaggct tctcggttaa
     7141 gcattccgtc tattttgtta agtaagctaa ctcaaattgg taagcagtct tatctagtgg
     7201 actttacagc tgtttatgat tttgtttacg ataaggaaac tgatcctgaa aaaggcacct
     7261 cagggaatgt tcgtcaagac ttgactggta agctgaccct gaaaaaatct ggggatagct
     7321 accttgttag tcagtctggt cctaaaaata ttacagttgc cagcgaaaaa aatcaggtca
     7381 agccgtctat tttcccagag gggctagtgg gaacctggat aggacatcgt tcggacatga
     7441 cctttacgat gatattggct aaggacggca gcatcacaac aaccattgga aacaaaaatg
     7501 ggaatggctc acagaccact aagtctgcta aaattaccaa ggtagaggaa aaaggagatg
     7561 gcttgttcct ctacactgta gctccagatg ctgatatagc agctcttgtt ccaggaggtg
     7621 gattgggtgg tgtcaatgtc aaatacgctt ttggtgtcaa atggagtgga gatgtcgcta
     7681 cgatagtggt ttggcagaca gcaaataatg cggcatttga ttacagtaag ccaatgcttg
     7741 gccctgacat gaaaaagcaa taagtacttt accctacaag ttggtctagc atttattgct
     7801 aggaggaatc agcataaaga aaaagcctct cttttaatct tttgtggtta agaagagagg
     7861 ctttttagta tagggctgac tgtatgagga gcaaccgatg taatcaattt agctgctgta
     7921 gtccttcttt aaagctttta gacggggcag tgaccctaat catctcttga gccaaggggt
     7981 gtctaagggt tagctgatga gcgtgcagca tgagacgctc cgctttttgc ctgctataga
     8041 ggggatcacc aattagaggg tgtttatgat gagcgagatg tactctgatt tgatgtgttc
     8101 gtcctgtctc taggcgacag ttgactaggc aggtctgatc aaaggcttgt aataaggcta
     8161 gatgggtgat tgcctcttgc ccatgcttac tatcaaccac acgcttgcgc ctatcgtggc
     8221 ggtgacgtcc gattggatcg cgataggtta ctgtttgctg ctctagctga ccttcgatta
     8281 gggcccaata atctcgctta atgtctcgat gctccaatag gcgatttaag atcggaagga
     8341 taaagggatt tttagcaaag agaatcgctc cactagtctc catgtctaag cgatgaacca
     8401 catagcaggt cttgccagta taggcagaga catggttgag caaggcgagc tcagtgggct
     8461 cattgccatg tgttttcatg ccctcgggct tgttgacaat gatgaggtgt tcgtcctgat
     8521 acaggcaatc cactaggcca ggcttaccca ttaagatgcc tttatcaggg tagtcttctt
     8581 ggtcaaattg tagcttgatg tgatcaccct gcttgacagg gctctgccag ttaatcagct
     8641 catcattgac ccaaacatgc tttttgatgc gcaagaaatg tctgatttta cggggaatca
     8701 atagcctatc ttctaataac tccttgacag ttgtcgcttg ataggggtta atgaaggaga
     8761 tctgaaagcc catctcaggc ttatttgctg ttgtcattga gccagtcatg gtatttttca
     8821 atcaaattga tggccatttg ggttgcaaga gttacagaga aagcctcggt tccctcgcgc
     8881 tcgtcactgg caacctctaa gcgtgtctca tcatagacag ccttgaggct ctctgctgac
     8941 agggtttctt taaaagcttg aaatttgttc atgatcatgt cctacctttc taaatgtttg
     9001 tgacaatgct attatagcat atttttcatc aaagctaatc atttgctcga tgatttgtgc
     9061 tgcgctaaca gcgtgattct tttgagaaaa aataagatta gctattgtga aattgtctgt
     9121 cttttattat actaagaata gtctgataaa tatattattt aaggacacga taacattggg
     9181 attatgaatc atttaggaga atactattga acaagccatt gataaaatcc tgtttgcttg
     9241 ctctattgac cttggccggc ttgaccagta tggcagcaca ggctgatgtc aacacttaca
     9301 accaaggtag gacatataac gatacaccct attattctgc ttatcatcac tactatgacc
     9361 acacgaggga tactgctgac aatggtattg ataattgggg tcgtctgaca cgctatcact
     9421 attacagaga gacctattat cagcttgagg ccgagcgtca gcagcttgtt aggacttact
     9481 tggagttgaa ggcttcatat gatgatcagg tggctcttag cagtcaacga ctacagcagt
     9541 accagtctgg ctggtctgat ctccaatcac gctttgagca gctcaggaaa accaatcctg
     9601 ttgtaggcgg tgattatcgg attgttgagc tagagggcaa ttttcaaagc tatcagacct
     9661 tgctgcagca gctttctatg gctgattttg tcagccagta caaagatagg ctggatacct
     9721 tgactagact tgatacagag cgagctaggc tcattgacac ctggtgggaa agtgatagca
     9781 attactcaga tctcaatacc aatctaacac tagtcaatgg ctatatcaag gagctgaatc
     9841 aggctttaca ggagcttctt aaggaccatc aaggtaaaat gacatcagat ctgcagacct
     9901 tgggtgaccg acaggccgag cttgctagac ggctgacaga tatagaaagc aggcctaaga
     9961 gacaggctac cagtcaacct cgtggttcac agacacattg gcgatcagcc cctagagctg
    10021 atgttgcctt gtggaatgaa ttgcgaaacg aaggagatta tgcttctgct acgacagaca
    10081 atgctttgcc attgcagcct tatcgagcgg acttaacagc tgttcatgat ctagaagcct
    10141 tgcaagcaca atctgataga gcacaccgct tgcgggcaaa ggaaattgtc tttacactgc
    10201 agcgttctaa cattagtcgt cagggcgata tagatttgtc aggagccatt acagcattta
    10261 tcaaagaaaa gcttctcgtc actccaaatg cgcgtggggt atcatctggc tttaggtggc
    10321 aaatgcaaac ctatgacaat gagcgcttaa ccatcactct aatgcctcaa tattatatga
    10381 ctgatgatca gtacaaggag tattacgacc atctcaaggc ttggacagct cagcatatcc
    10441 agtctaccga tacagaggtt gagaaaattg ataagattca agactatatc atgacaaact
    10501 accactatgc gaccggcaag gttggaggag tgacccgtac tggcatttct gtgcagacgc
    10561 catatgcctt tatcaaggac aaggaggctg tttgtcaggc ctatgcacag atgtttaagg
    10621 acatgggacg actagctgga cttgatgttc attatattca aggctatgga gacccagttg
    10681 gcggcttatc aagtctacat gcttggaata tcgtcaaggt tgatggtcaa tattatcata
    10741 ttgacctgac ttggaatgat actattgaca gcaccaatca caatcatacc tacaccctgc
    10801 gaggcaatga ttttatgagc aaaacacatt tgtggaatgc tgcctatgcg atctcagata
    10861 gtgactatgc tgcttatcct aggaggagct tcctgagata tgggacctat gcgactaact
    10921 attcaagaaa tacattttat ccaggataca gttatgctta ataatagcta ataccatcaa
    10981 aagccctaga aagcttgctt gattctttca gggctttttg atatgtcatg gtttttggta
    11041 taggattttg aaagaaattg ttataatagg ataaaatgct tatgtaacag gagaaaataa
    11101 aatgaagagt attagacgct atgatgtcaa tgaagagtgg gcacatactg gcttagtaga
    11161 ggcaggcgat ttttattttt taaattattg tgtaggaaat gtcggtcaag atattgaggc
    11221 tcaaattaac ggtgcctttg atgaaatgga gcgtcgtttg gggctggtag ggctgacgct
    11281 agaggtcgtt gttcaaatgg attgcttgtt tagagacatt tggaatgtgc cagttatgga
    11341 aaaaatcatc aaggagcgat ttaatggcaa atacccggct cgtaaatttc ttcaaacagc
    11401 ctttgctcat cagggtggtc cggacggctt gctatttcag gtagatgggg ttgcttattc
    11461 aaagcatatc tccgtatcct aaacaatatg acttggaggc ttagtagtat cataaggcta
    11521 tgacattttt agaattatta caaaagaaat tttttccaaa aaaataccaa gaaaaacagg
    11581 ccttaaagga aagggcagcc cagcatatgg ctgacaaaga ggctactact caggctactg
    11641 ccactgcttt ggccgatcag gaggcacagg cagggcagac tgagaggcaa tcagtccttc
    11701 aacgcagcaa gtcctatggg gtcaaaagga aaaatcggcc gatctggctt caaaggctgg
    11761 aggcgatttt gccatcgcag caaggtccta ttcgccgctt tcttcgtcgt taccatgttg
    11821 gtaaaatcct gctgattttg atgggtacct ttgtcttgct gctggggtct tacctttttt
    11881 acctttcaaa gacagctaag gtttctgact tgcaggacgc tcttaaggcg acgacagtca
    11941 tctatgaccg caagggagaa tatgcaggca gtctttctgg tcaaaagggg acctatgtgg
    12001 agcttgacgc tatttcagat gatttggaaa aggcggttat tgccacagag gaccgtacct
    12061 tttataccaa caatggtatt aatttcaagc gctttttatt ggctattgtg accgcaggac
    12121 gctttggtgg aggctcgacc attactcagc agttggctaa aaatgcttat ttgtcccagg
    12181 agcagagcat taaaagaaag gcgcgtgagt ttttcttagc acttgaattg accaagaaat
    12241 acagtaaaaa tgacattttg accatgtatc tcaataattc ctattttgga aatggtattt
    12301 ggggtgttga ggacgccagt caaaaatatt ttggtacctc agcagctaat ctaaccttgg
    12361 acgaggcagc aacccttgcc ggtatgctca agggacctga aatttacaat ccctattact
    12421 caatcgaaaa ggcaaccaac cgtagagata ctgttttgtc agccatggtt gacgctggaa
    12481 aaatcagcaa gcagcaggca caagaggccc aagctattgg tatggggaac cgtttagcag
    12541 acacctatgt cggcaagaca gatgattatc agtacccatc ttattttgat gctgttatca
    12601 atgaggctat ctcgcgctat ggcatctcag aaaaggatat tgtcaatgat ggctacaaga
    12661 tttacacaga gttggaccaa aattaccaag caggcatgca gaccaccttt aatgaggata
    12721 gcctatttcc tgtgtctgag tttgacggca gctcagctga ggcggctagt gtggctctag
    12781 atcctaaaac cggagctgtc agggggcttg ttggtcgtgt caatagcaca gaaaaccagc
    12841 cctttagaag ctttaactat gctactcaag ccaagcgtag ccctgcttca acgatcaagc
    12901 ccctagttgt ttatactcct gctgttgcag caggctggtc actggagcac gaactgccaa
    12961 acagcgttca ggattttggc ggttatcagc cgcataatta tggcaattac gaatcagaaa
    13021 caattcctat gtatcaggct ttggctaatt cctacaatat tcctgctgtt tcaattctgg
    13081 atcagttggg ggtggataag gcctttagct atggtgaaaa atttggtttg aagatgagtg
    13141 aaaccaaaaa ggagcttgga gtggcgcttg gtagtggtgt caccaccaat ccgcttgaga
    13201 tggcacaggc ctatgcagtc tttgccaatg gtggtgtcaa gcatattgcc cacctgatta
    13261 ccagaattga aaatgctaag ggcaaggtta tcaagacctt tacagacaaa accaagcggg
    13321 ttatcagtca atcagtggct gataagatga ctagcatgat gcttggaacc ttttctaatg
    13381 gtacagctgt taatgccaat gtctatggct atactctggc tggtaaaaca gggaccacag
    13441 aaactgactt taacccggac ctttccggtg atcagtgggt cattggctac acgccagacg
    13501 ttgttatcag tcaatgggtt ggcttcaatc aaaccgatga gcatcattat ttatcagatt
    13561 caagtgcggg cactgcctca gcaattttta gcacccaagc ctcttatata ttgccatata
    13621 ccaaaggaag ccaattcaag gtcgataacg cttacgctca aaacggtatt tcagcggttt
    13681 atgggattaa tgagaccaat acgcaagcag gtattgattc tcaatccatc attgatagtc
    13741 ttagaaagtc agccgaggaa gcttcaaagt ctatttcaga ggcagttgat caatctggtc
    13801 tcagagaaaa ggcgcaaagt atctggaaga gtattgttga ctactttaga tagcttgcga
    13861 aaatatctaa atcgtgttag aataatcact acggaggcgt tatggcacag aaaaaagcaa
    13921 gcctagcgtg tgtagaatgt ggcagccgca attattctat cgggattagt agcacgccta
    13981 gaccaacacg actagaagtc aataagtttt gcaaatattg taaagcatac accttacaca
    14041 aagaaacacg ttagaggaga gcctgatggg attcattagt gggattttta agcttttaag
    14101 ggatacaact tggccggatc gtaagcagcg ctggaaggac tttatttctg tccttgagta
    14161 tacagcattc tttacggtaa tcatctttat ctttgaccag ttgctatcaa aaggcatttt
    14221 atcattgatt aatttattct aagtcattgc aatgatgaga cctgttatga ttaaaattgc
    14281 ttggaaaagc ctaggctgaa acaatcgttt cggccttttt gagtgcgatg ggcaggttgt
    14341 actctgatag atgcaagacc aatagaccac ctactatgcg ggtgcgtaaa ggggttgata
    14401 gctaccgata gttaagggct atagcaagta gaaaggcttg cagctcagct gatccgctgt
    14461 tatgactaaa ggcattgacc agaaaggttc gttggcagcc aacaaagtgc tcttaccctg
    14521 ctatgagggg ctattaatgc gttgacagcc aatccttctt ctattataat gaaagtgtga
    14581 taacagcaat gcaaaggcca gcagaggctt ttttataatg aaaggaagta acatgttaga
    14641 ttcttttgat aagggctggt ttgtccttca aacttactca ggctatgaaa ataaagtaaa
    14701 agaaaacctt ttgcagcgtg ctcaaaccta taacatgcta gacaatattc tccgcgttga
    14761 gattcctacc caaacggtaa atgttgaaaa aaatggtcag gtcaaagagg ttgaggaaaa
    14821 ccgcttccca ggatatgttt tggttgagat ggttatgact gatgacgctt ggtttgttgt
    14881 tcgtaacaca ccaaatgtga caggctttgt cggatcgcat gggaaccgct caaaaccaac
    14941 ccctctactt gaagaggaga ttcgtgctat cctgttgtca atgggacaaa ctgttgatgt
    15001 ctttgatacc aacattaaag agggcgatat ggttcaaatc attgatggcg cctttatcgg
    15061 gcaagagggt cgtgtcgtag aaattgaaaa caacaaggtc aagctcatgc ttaatatgtt
    15121 tggctcagaa accttagcag aggtcgagct ttaccaaatc gcagagctat cgtcctgata
    15181 ggctcctaaa gctattattc ataccataaa aaataaaagg ctggcatcgg ctctctaaaa
    15241 taccgatgtt aggccttttt tgttggtctt ctacaaccaa gactcaaatt aaccaaaccc
    15301 taaaaagagt catttttcct tcgcttttta agtctctaac tgatcgccct agcttatttt
    15361 taatctagta atcgcaacag gtcaagagtt aaatgatatc gcgccgttat tgattggtat
    15421 agacaaaaat acgctcaaaa aaagaaaaaa ggataggtaa tatagtcctg gtttgcttga
    15481 tagatggtgg ttggcaacca accattcgag tactttcctt aactataaac tcctaatcaa
    15541 ttctagcgtt taaaaaataa gattattctt ggagggaagc aaagagcttc tctccttttt
    15601 gagttgtagc attcttgatc ctgatcttat aagcagagtc ctgtttgccg ggctgttgag
    15661 atgaataagg gcatttctat agtgattata tagtgttgca gatgtgtgta tggtttaagg
    15721 tctaaatacc cttcaagctt agttcttggg tagtcagttc ggattggctg gctgattttt
    15781 aagcctttaa tggcttagtg gtaagacaaa ccagattaca tttgctaaaa agtccctaag
    15841 gctacaatca ttttttgtga ctaatataaa aactagacct tttgggattt gtaataattt
    15901 agattattgt ttttaaaatt agcaaatatt aaacgctttt ttattgaaga tacagatgat
    15961 agtaatggca gagctaaaaa ataagagaaa ataaaaaaag tctacaattt ataatgtaat
    16021 aaaaaaatga gttgactgtt gtgttttaaa ggcttttgtc tatttgtaat cggttaattt
    16081 gcaaacaatt ctaaggtatt tctggctaat agtatgctat aatgtaatac tgttctacaa
    16141 ccgacattaa gagttaatga aatagtgttg tgttgtggta agtttttaat caggaagagt
    16201 atatttagga gctagatacc atgtctatag agaatctctt taccaagcag cagtggcgag
    16261 agcttgagtt gattacttta ttaagtgaaa cgaaaaatcc attatattat aaagatgctt
    16321 gtcagatgct ggattgttcg gttttaacgc tgcaatcgtg tatcacgaat tctgttttta
    16381 tggaagattt aggcaagctg ttctacaagg attctcaatt tcatattcat tacaatcatc
    16441 aaagtggctt aaaggaggtt tatcggagag ccttgctaga gtctccttct cttcagttga
    16501 tgtcggcctt gttttttgat gattttgcgt cattagatga tcttgcagag gcacttttta
    16561 ttagcttgtc aaccttaaag cgcttgattc gtaaaaccaa tctctattta aaagagcatt
    16621 ttgatattat catttcggct aagcccattc gtgtagttgg agatgaatac aatattagac
    16681 tgttttacat caagtatttt tcagaagcat ataccttttc tgaatggcct tttgcttctc
    16741 tacttaatga aaaccaccat gagcaatttg ttcaattaat ggcatctttg atagaggtta
    16801 agattgattt tgcgattttt cgtcaactca agctattaag tgcggttaat ctcattcgct
    16861 acctcaaagg ctttaaaatt gggaagcata aagcactgag tagtctttca ttggagttgt
    16921 tacaggattc tcaggagatg aaaaagctgt cgcatttgtt tgtgcttaaa ttttcagtac
    16981 cgcttgatga gcttgtcttg tcagaaatgt tttccaatta tttagatgat gatttggtat
    17041 tagaaaaatc cttgcaggta gataaggtta aggaggaggt tccgggtcct cagtccttgc
    17101 tgagctggat agatttgctt agtgaaatgg agggagctac aggtattgta ttgccaaata
    17161 aatatgaggt tgccagatat cttcatgcca ctgttatttt aggagtggag gatattagtg
    17221 aaagctttct gatttacgat tataaaaagg attacttggc cttctttaag gagcattata
    17281 cctatgttta ttttaggttt accgattatg tgaagaggct atttaaggac ggggatatgg
    17341 agcttgctac taatttgctc aacaatttgg tttattcctt gctgatagcc tgggagaatt
    17401 tctttttaac catgtgtgaa ttgatgaaaa aaccaaagct cttgattata gaaagaagtc
    17461 atggcagtac gggaagcttt ttgaaaaaat acattggtga attttttgag attaccattt
    17521 ttgataaatt aaccatagaa gccttgtgtc tacagcatga ctatgacgtc attattactg
    17581 atacggtcat taggggctgt gagcatgctg atatcttttt ctttagtcga tttgtgccaa
    17641 ccgttatagt cgccaagctt aaccattatc taagaaaacg aatgggtagt atctttgaaa
    17701 cgaaaacaac taacaagctt gggaacatcg gctattgata gatatcggta tatttcatta
    17761 aaatagccac aacttgtcat ggtgtaaaat tagtgagctt tgttaatcca ataaaattag
    17821 gtagaatata gctataggcc aacgtgtaat tcccttaggg agtaggtgct ttggtctggg
    17881 aaagagaaaa ataaaaagga gaaacaaaca acatgaagag ttgtaaatca accctagttt
    17941 agataaaaag attaattctt ctattggtat caaaggaagt aattttattt cctcaaaact
    18001 tttagcgaat ttaaagactc gcatcgactc tgaagctact ttgaaagcag aaacaactca
    18061 attgaaagcc gatatagaaa gagaaaaact tacttctaaa gaattaagca ctaaactgga
    18121 agaggtaaca tcagatcgtg ataatgctct cagtgaatct gccgatcttg ccaacaaact
    18181 ctcagtagct caagcagaag cagatcgttt aagtcaggct gttgatagtc tgggtcgatt
    18241 gactaactct gctaagcgtg agctcacaga gaagcttgct gagattgatc aattaacaca
    18301 ggacaaggtt aaagcagaga ctgaccttga aactgctaat gctaacatca caacacttca
    18361 agaggagctg gcaggtgcta aggctaatgt tgataagctt gcaaaggaaa aagctgcggc
    18421 agatcaggca cttgctgaag ctaatgcaag agtatcaaat cttgggcaag aggtagcagc
    18481 agctaataat agagtggctg accttgaagc gcaattagct gaaaaaacag ccgagcttga
    18541 tgtggttaag gcagacaagg cagagcttga ggctaaggtt aaggagcttc aaagcctgct
    18601 tgagcaaaag gatcgtagca atgctgatct tcaagctaac attgagcgct tgaagcagga
    18661 gcttgctgac aagtttaagg atcaggcaca gcctcgttct aagactcctc aggcatcgaa
    18721 ctcggttgca aagcaaaaag caagtaagcc agccgcaaaa ccagcaggcc agctaccatc
    18781 aacaggtgaa gctactgcaa atccattttt cactgctgct gcagttgcga ttatgacaag
    18841 tgcaggccta gtaacagtca tgccaaaacg ccaaaaaaat taagctattc tcaattctct
    18901 cccctttaac tattgtttta tagcatttta ctaatggaca ttggcattcc tataaactct
    18961 attgagcttc ttatctgata gcaaggataa ggggcttttt agtagcttag caagcactcc
    19021 ttggtcaagc tcaatacctc tttgagagct taaaactaga gctagaccag atctaaaacc
    19081 aagtgagatg atagcggata tttggctgtt ttatgagttg gctcgtaagg cttgagctta
    19141 tgcgtcgcag agacgcgcta tctagtctaa agggctttag caatgtcgtg acaaacgcat
    19201 gaagacagtt acactttctc atagcgagtt tttatcatca gtatagtttt tttggcaata
    19261 tgttatgaaa tagtcaaata gcaatcgaga aactggtgat attgcaatgc aaaaccgctg
    19321 aacatagatt aaaaaaatgc atgcagctag aaaatggtta catgcatttt tgtgatgccg
    19381 acgtcgtggc agcaatattg cttgcccatt cctaaaagtc tgatatcgtg ctataataag
    19441 aagactagac tttttacatg ggagaattca catgacattt tacaatcaca aagccattga
    19501 gcctaagtgg caggcctttt gggctgataa tcataccttt aaaacgggga cagatgcctc
    19561 aaagcctaaa ttttatgctt tagatatgtt tccttatcct tccggtgcag gtcttcatgt
    19621 tgggcatcct gagggttaca ctgcaactga tattttaagc cgcttcaagc gtgcacaggg
    19681 ttataatgtc ctccacccaa tgggctggga tgcctttggt ctgcctgctg agcaatacgc
    19741 gatggatact ggtaatgacc ctgctgagtt tacagcagaa aacattgcca actttaaacg
    19801 tcagatcaat gctcttggct tctcgtatga ctgggatcgt gagatcaata caactgatcc
    19861 tagttactac aaatggacac agtggatttt cacaaaattg tatgaaaaag gcctagccta
    19921 tgaagctgag gtgcctgtta actgggttga agagctggga acagctattg cgaatgagga
    19981 ggttctccct gatggcacat cagagcgtgg aggctatcca gttgtccgta agcccatgcg
    20041 ccaatggatg ctcaaaatca cagcctacgc agagcgcttg ctagcagatc tggaggaagt
    20101 ggattggcca gagtcgatca aggatatgca gcgcaactgg attggtaaat caacaggggc
    20161 taatgtaacc ttcaaggtca aagataccga taaagacttc accgtcttta ccacacgacc
    20221 tgataccctg tttggtgcaa cctatgctgt tttggcacca gaacacgcct tagtagatag
    20281 cattactaca gcagagcaag cgcaggctgt tgctgagtac aaacgccaag cgagcctcaa
    20341 atctgacctt gctcgtaccg atcttgccaa ggaaaaaaca ggtgtctgga caggagccta
    20401 tgcgatcaac ccggtcaatg gcaaagaaat gcctatctgg attgcggatt atgtgcttgc
    20461 aagctacggt acaggtgcta tcatggcagt gccagcgcat gatgagcgtg actgggcatt
    20521 tgcaaagcaa ttcaatcttg agattattcc agtgcttgaa gggggcaatg ttgatgaggc
    20581 tgcctacaca gaggacggta ttcacattaa ttctgacttc ctagatggtc ttgataaggc
    20641 ttgtgccatt gctaaaatgg tggcgtggct ggaggagact ggtgtcggtc atgaaaaggt
    20701 ctcttatcgc ctacgtgact ggctgttcag tcgtcagcgc tactggggtg agccaatccc
    20761 aatcattcat tgggaggacg gtacctcgac agcggttcct gagcaggacc taccacttgt
    20821 tttgccagtg accaaggata ttcgcccatc tggtacagga gaatcaccac tagctaactt
    20881 gactgactgg cttgaggtga cccgcgagga tggggtcaaa gggcgtcgtg agaccaacac
    20941 catgccacag tgggctggct caagctggta ttaccttcgc tatattgacc cacacaatga
    21001 tgagcaatta gctgataagg acctgttaaa gcaatggctg ccagtagata tttacattgg
    21061 tggtgctgag cacgcagtgc ttcatctgct ttatgcacgc ttctggcaca aggtactcta
    21121 tgatctgggt gtagtgccaa ccaaggagcc cttccaaaag ctctttaatc aaggcatgat
    21181 tttgggaacc agctatcgcg accatcgtgg ggccttggtc gcaacggata aggttgacaa
    21241 gcgtgatggt agcttcttcc acatggaaac aggcgaggag cttgagcagg cccctgctaa
    21301 gatgtctaaa tcactgaaaa acgttgtcaa cccagacgat gtggtggagc agtacggagc
    21361 agataccctg cgtgtgtatg aaatgtttat ggggccactt gatgcgtcca ttgcttggtc
    21421 tgaagaaggc cttgagggag cacgcaagtt cctagatcgt gtttaccgtt tgatcacgac
    21481 aaaggaaatt gttgcagaaa atagcggagc tttagataag gcttaccatg agactgttaa
    21541 ggcagtcaca gaacaaatcg aaggcatgaa attcaatact gctattgccc agctcatgat
    21601 ttttgtcaat gcagccaata aagaggacga gctttatgtg gcatacgcca aaggcttcgt
    21661 tcaattgcta gccccatttg ccccacacct aggtgaagaa ttatggcaga tcctgacagc
    21721 ttcaggtcaa tccatctcgt atgttgcatg gccaacccat gacgatagta agctcgttga
    21781 aaatgatgtt gaaatcgttg ttcaaattaa aggaaaggtc aaggctaagc ttgtcgtggc
    21841 aaaagacctc tcaagagaag agctagaaaa agtagcccta gcacatgata aaatacaggc
    21901 tgaaattgca ggcaaggaag tggcaaaggt catcgttgtt cctaataagc tcgttaatat
    21961 tgtggtgaaa taaagaccct agcaaaaaat gccttcctta taattttgag cccaatacta
    22021 taaaaagctg ataaccactc gtttacatga gtggttattc ttgttttgta acacgctatt
    22081 aaaactgata ttgaagaagc ttgaagataa tagtaaaata aaaccctaaa cttatttaat
    22141 aaatggagga tttttcaacg tgaaaaaatt agttttagcc agtgcagcag cacttgtatt
    22201 agcaggagca actgtaagta caggaacagt aagtgcgaat agttcaagat ataattatac
    22261 cggttggaat caaggtgggt actcatggaa atatttgcgc ctaagaaata aaaatcctta
    22321 ttcacgtcgt acccttacag aagactattc tgatcaaaga aagaatgaag caaaagatag
    22381 tattaaagaa ttgagtaagc ttagtgataa agagaaaaag aattttgctg atagaattga
    22441 tgctttgact gacacctatg caatcagctc tattctatca gaagctaaaa ataagaataa
    22501 tgactattta gaatttgata aagaatatga ggctttattc aattcaaata agtataagtt
    22561 agaaatagag aaaataaagg atcgtgtgta ctttgatgaa ggttactcag ctagacaagg
    22621 gattaatgac ttgaaaagtc tggagaatta aacagtagac agatttatta tttatcaaaa
    22681 taatccaact gaaagtctat gttttaagga agcttattaa ggtataattt ataagaaaaa
    22741 tggttcagaa tagtattttt ggaccatttt tctgttaatt taatgataaa t
//
LOCUS       DARYLD010000034        22622 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYLD010000034 DARYLD010000000
VERSION     DARYLD010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22622
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            429..1913
                     /locus_tag="TU651_001186"
     CDS             429..1913
                     /locus_tag="TU651_001186"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL0897193.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            1953..3254
                     /locus_tag="TU651_001187"
     CDS             1953..3254
                     /locus_tag="TU651_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL0897194.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            3634..3942
                     /gene="rpsJ"
                     /locus_tag="TU651_001188"
     CDS             3634..3942
                     /gene="rpsJ"
                     /locus_tag="TU651_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL0897195.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPFPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            4240..4866
                     /gene="rplC"
                     /locus_tag="TU651_001189"
     CDS             4240..4866
                     /gene="rplC"
                     /locus_tag="TU651_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL0897196.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            4891..5514
                     /gene="rplD"
                     /locus_tag="TU651_001190"
     CDS             4891..5514
                     /gene="rplD"
                     /locus_tag="TU651_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL0897197.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            5514..5810
                     /locus_tag="TU651_001191"
     CDS             5514..5810
                     /locus_tag="TU651_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL0897198.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            5828..6661
                     /gene="rplB"
                     /locus_tag="TU651_001192"
     CDS             5828..6661
                     /gene="rplB"
                     /locus_tag="TU651_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL0897199.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            6773..7051
                     /gene="rpsS"
                     /locus_tag="TU651_001193"
     CDS             6773..7051
                     /gene="rpsS"
                     /locus_tag="TU651_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL0897200.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7067..7411
                     /gene="rplV"
                     /locus_tag="TU651_001194"
     CDS             7067..7411
                     /gene="rplV"
                     /locus_tag="TU651_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL0897201.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            7424..8077
                     /gene="rpsC"
                     /locus_tag="TU651_001195"
     CDS             7424..8077
                     /gene="rpsC"
                     /locus_tag="TU651_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL0897202.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8081..8494
                     /gene="rplP"
                     /locus_tag="TU651_001196"
     CDS             8081..8494
                     /gene="rplP"
                     /locus_tag="TU651_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL0897203.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            8504..8710
                     /locus_tag="TU651_001197"
     CDS             8504..8710
                     /locus_tag="TU651_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL0897204.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            8735..8998
                     /gene="rpsQ"
                     /locus_tag="TU651_001198"
     CDS             8735..8998
                     /gene="rpsQ"
                     /locus_tag="TU651_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL0897205.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9023..9391
                     /gene="rplN"
                     /locus_tag="TU651_001199"
     CDS             9023..9391
                     /gene="rplN"
                     /locus_tag="TU651_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL0897206.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            9475..9780
                     /gene="rplX"
                     /locus_tag="TU651_001200"
     CDS             9475..9780
                     /gene="rplX"
                     /locus_tag="TU651_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL0897207.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            9804..10346
                     /gene="rplE"
                     /locus_tag="TU651_001201"
     CDS             9804..10346
                     /gene="rplE"
                     /locus_tag="TU651_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL0897208.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            10362..10547
                     /locus_tag="TU651_001202"
     CDS             10362..10547
                     /locus_tag="TU651_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL0897209.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            10880..11278
                     /gene="rpsH"
                     /locus_tag="TU651_001203"
     CDS             10880..11278
                     /gene="rpsH"
                     /locus_tag="TU651_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL0897210.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            11600..12136
                     /gene="rplF"
                     /locus_tag="TU651_001204"
     CDS             11600..12136
                     /gene="rplF"
                     /locus_tag="TU651_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL0897211.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            12239..12595
                     /gene="rplR"
                     /locus_tag="TU651_001205"
     CDS             12239..12595
                     /gene="rplR"
                     /locus_tag="TU651_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL0897212.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            12614..13108
                     /gene="rpsE"
                     /locus_tag="TU651_001206"
     CDS             12614..13108
                     /gene="rpsE"
                     /locus_tag="TU651_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL0897213.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13123..13305
                     /gene="rpmD"
                     /locus_tag="TU651_001207"
     CDS             13123..13305
                     /gene="rpmD"
                     /locus_tag="TU651_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL0897214.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            13507..13947
                     /gene="rplO"
                     /locus_tag="TU651_001208"
     CDS             13507..13947
                     /gene="rplO"
                     /locus_tag="TU651_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL0897215.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            13964..15268
                     /gene="secY"
                     /locus_tag="TU651_001209"
     CDS             13964..15268
                     /gene="secY"
                     /locus_tag="TU651_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL0897216.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            15420..16061
                     /locus_tag="TU651_001210"
     CDS             15420..16061
                     /locus_tag="TU651_001210"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL0897217.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16179..16397
                     /gene="infA"
                     /locus_tag="TU651_001211"
     CDS             16179..16397
                     /gene="infA"
                     /locus_tag="TU651_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL0897218.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            16423..16539
                     /gene="rpmJ"
                     /locus_tag="TU651_001212"
     CDS             16423..16539
                     /gene="rpmJ"
                     /locus_tag="TU651_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL0897219.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            16557..16922
                     /gene="rpsM"
                     /locus_tag="TU651_001213"
     CDS             16557..16922
                     /gene="rpsM"
                     /locus_tag="TU651_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL0897220.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            16940..17323
                     /gene="rpsK"
                     /locus_tag="TU651_001214"
     CDS             16940..17323
                     /gene="rpsK"
                     /locus_tag="TU651_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL0897221.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            17370..18308
                     /locus_tag="TU651_001215"
     CDS             17370..18308
                     /locus_tag="TU651_001215"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL0897222.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            18323..18709
                     /gene="rplQ"
                     /locus_tag="TU651_001216"
     CDS             18323..18709
                     /gene="rplQ"
                     /locus_tag="TU651_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL0897223.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(18927..19158)
                     /locus_tag="TU651_001217"
                     /pseudo
     CDS             complement(18927..19158)
                     /locus_tag="TU651_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20014..21264
                     /locus_tag="TU651_001218"
     CDS             20014..21264
                     /locus_tag="TU651_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897224.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            21254..22129
                     /locus_tag="TU651_001219"
                     /pseudo
     CDS             21254..22129
                     /locus_tag="TU651_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22150..22443
                     /locus_tag="TU651_001220"
     CDS             22150..22443
                     /locus_tag="TU651_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL0897225.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         6967 a         4063 c         5027 g         6565 t
ORIGIN      
        1 tcactaagaa aaatcacttg attattgctt agttttttct aatggaggat ttttagttta
       61 gaagctttga gtttagacct caaaacttag atatggaatt cgaaaggcag tcactgctgt
      121 caacattact ttgggaaagt tcctataaga gacttttcat tagactgaag tagcttcaat
      181 agctctaaaa ctacctagac tcaagtaaca acaagtcctt agaattgatt ttctaagggc
      241 ttttttgctg cctcaaggta aagacatgtt cagcaacaaa ttgactggct agaccagtcc
      301 tttatttatg ctgatggctt gagactgctg ggttattagc acagaaaatg gctgtctcca
      361 aatcctagaa ggcttatgat tggaatatga tataatagtc aaaagaaatg atgaggtgat
      421 gtgaagcaat gccaatgatg taccaatcaa caagaaatgc agctaataag gtaacagcta
      481 gtcaagcgat tttaagtggc ctagcagatg atggtggctt gtttactcct acaagcatgc
      541 cagtgctgga tctagatttt gaggagctaa agaccaagtc ctatcaagag gttgccaagc
      601 ttattttatc agcctttttt gatgactata ctgaagcaga attagatgct tgtatctctt
      661 ctgcctatga tgataagttt gatacagcag tgatagcacc tctagctacg ttaaaggatt
      721 atcataattt ggagctattt catggctcaa ccatcgcatt taaggacatg gctctatcta
      781 ttttgcctta tctcttgaca actgctgcta aaaagcaagg tgtggagcga aaaattgcga
      841 ttttaaccgc tacctcaggt gatactggta aggcagcaat ggcaggcttt gttgatgttc
      901 cgggaacgga tattattgtc ttttatccta agtcaggcgt tagcaggatt caggagctgc
      961 agatgatcac acaggccggt cacaataccc atgttgtggc gattgaaggc aattttgatg
     1021 atgctcaaac agaggtcaag cgcctgttta atgaccctga tttgcgtgag cggctagcag
     1081 ctcaacagat acagctgtct tcggccaatt cgatgaatat tggtcgtttg attcctcagg
     1141 ttgtctatta tatttatgct tatgcccagt tggtaaggca tcagcgactt gaagctggag
     1201 agacgattaa catagtagtg ccgacaggaa attttggcaa tctactggtt gcctactacg
     1261 ccaaagaaat tggacttcct gttgccaaat tcatctgtgc ttccaatgaa aacaatgtct
     1321 tgacagattt ctttgctagt ggtaggtatg ataaaaagcg tcccttcaag gtgactacta
     1381 gtccatcaat ggatattttg gtgtcttcaa atttagagcg cttggttttt tatttactag
     1441 gcaatgatgc ccaaaagaca gcagtattaa tgaagagctt ggcagaaaca ggtcagtatc
     1501 agctagctga tgcagatcag tctatccttg atttatttgc ggcaggcttt gcaacagagc
     1561 aagagactgc taaagagatc aaaacgatat ttgagtctga tcattatgtg cttgacccac
     1621 atacagctgt agcttcagct gtttatcgtg cttatcggga gcaatcaggt gactctagac
     1681 cgactattgt tgcgtcaact gctagtcctt ataagtttcc gcgggtagtt gtggaagcta
     1741 ttagtggtca gcaggttgcc agtgattttg aggcgcttga gcagttggct gatatatcag
     1801 gtgtagtcgt gccacaagcg gtcaatggct tacaggaggc gcccattcgt catagccttt
     1861 tagtgacagt agcagatatg cagcaggcag tagaggctta tcttggagta taggaggcat
     1921 aaaggagctc cctttcaatt gatatgaata taatgactca caatagaaaa aagatactgt
     1981 ccttggccct tccatcaatg gcagaaaata tattgcaaat gctgatggga atgatagaca
     2041 attatttggc tgctcaaatt ggacttacgg ctgtttcagg cattgcgatt gctaataata
     2101 ttctgacgat ttatcaggcc ctttttatcg cattaggtgc tgcagtctcc agtctcattg
     2161 ctagaagcgt aggagagcaa aaccattcta aagaaatcga ctacatggca aatgctatct
     2221 tagtaacggg ggctctatca gttcttctag gcttgatgtc cgtagtggga cataaaagca
     2281 tattagcctt tctgggagca gctagtctgg tagctagact tggtgggcag tatttagcca
     2341 ttgtcggtgg aatgattctt agtcttggtc ttttcacgag cttaggtgcg attattcgtg
     2401 ctaagggcca gcctagcatt cccatgaagg tcagcctttt aactaatttg ctaaacgctg
     2461 tattttcagc cctttctctt tacatatggg gatttggagt gatagggatt gcttggtcaa
     2521 ctgttgcatc acgtctcatt ggagttgtta ttctatgtca ctttcttcct attaaagaaa
     2581 ttattaaacg ttttgctaat cccttagata aagagatctt tagcctctct cttccagcgg
     2641 ctggtgagcg gctcatgatg cgagctggtg atgtgctgat tgttactatt attgttagat
     2701 ttggaacaga ggccttggca ggcaatgcga ttggagaaac cttaactcaa tttaattata
     2761 tgccgggact tgctatgtca actgcgacag tcattttagt tgccaatcag ttgggcagtg
     2821 gcaaaggggc tacaatagcg aaaactgtaa aagaaacctt tttgttagcc accctgatga
     2881 tgcttgttat gggcttgatc acttatttgc taggccctaa tctactgccc ttatttacag
     2941 cagatgccaa ggctcagcag gctggtatgg ttgtcttagt cttttctctt ttgggggtac
     3001 cagcaacagc cgggaccttg gtttatacag cagcctggca gggtatcgga caagctaagc
     3061 ttccctttta tgcaacaacg attggtatgt ggctggttcg gatttctttg ggctacttta
     3121 ttggagtaac cttaaattat ggagtaatag gtgtttggct tgcgactatt ttggacaatg
     3181 ctaccagatg gctcattctt gcagtggctt ttaagaagca gcaaaggcag cttttttcgg
     3241 actgtcatag ctaaactttg tatttaggtc tcaagacttc tgagtggtga ctttcctttt
     3301 gggagtcagc cactgtcatc agaatgtaaa gtacgcctga ggctctgttt gctaatagct
     3361 tctcttatct gcggaagatc aaagaggatt gctggaacag ctgaggtttg tcttcaatct
     3421 ggcttgccct ttcttagggc aagttttttt gaaaaaatcc cctgaaaggc ttgcaatgcc
     3481 ttattaattc tgctattata ttatggtgct gtaaaaatac agctttagct gtgatacgag
     3541 aggttgcgac acgctcggtt gcattgccac gtgacaggtg tcggttttct cgaggagcta
     3601 gcctattatc gtaaatagac gagaggagaa aagatggcaa acaaaaaaat ccgtatccgc
     3661 ttgaaagcgt acgaacaccg tacacttgat acagcggcag aaaaaatcgt tgaaactgca
     3721 actcgtacag gtgcaacagt agctggacca gttccatttc caactgaacg tagtctttac
     3781 accattattc gtgcgactca caagtataaa gattctcgcg aacaatttga aatgcgtaca
     3841 cacaaacgtc ttattgatat tgtgaaccca acgcaaaaga ctgttgatgc acttatgaaa
     3901 ttggaccttc caagtggtgt caacgtagaa atcaagcttt aattgtttga aacatgagtg
     3961 aggaacgagt tcatatctaa ttgaacacag gctaaactct gtgtgaaaaa gagacacagc
     4021 cgttctaatt ttaattagat tacggatgtg gctacctgta ggtgtaaatc ttcctagaaa
     4081 cagaagtttc ttcgtcagat ttcctatttt cactgtgagt ttgacgcctt aagtatcttg
     4141 ctttgagcat aaaaaacgct cgtaaaaaac ttttttgagc ataaaaaacg ctcactaaaa
     4201 actttttgaa atattattaa gaaaaggaat tattttctca tgacaaaagg aatcttaggg
     4261 gaaaaagtgg gaatgactca aatcttcact gaatccggtg aatttatccc tgttactgtc
     4321 atcgaagcaa ctccaaacgt tgtgcttcaa gttaagactg ttgaaacaga cggttacgaa
     4381 gcaattcaag ttggttttga tgataaacgt gaagtattga gcaacaaacc tgccaaaggc
     4441 catgtagcaa aagctaacac agctcctaag cgcttcattc gtgaattcaa aaacattgaa
     4501 ggcttagaag taggtgcaga aatcactgtg gatatcttcg cagctgggga tgttgttgat
     4561 gtaactggta cttcaaaagg taaaggcttc caaggtgtta tcaaacgcca tggtcaatca
     4621 cgtggtccga tggcccatgg ttctcgttac catcgtcgtc caggttctat gggacctgtt
     4681 tcaccaaacc gcgttttcaa aaacaaacat ttggcaggac gcatgggtgg caatcgtgta
     4741 actattcaaa atcttgaaat tgtacaagtt atcccagaaa agaacgttat tcttattaaa
     4801 ggtaacgtac caggtgctaa gaaatctctt atcaccatca aatcagcagt taaagctgct
     4861 aaataataag aaaggagaaa acagttaaaa atggcaaacg taaaactatt tgaccaaact
     4921 ggtaaagaag ttagcacagt tgaattaaat gatgatatct ttggtatcga accaaacgaa
     4981 tcagttgttt ttgatgttgt aatcagccaa cgtgctagcc ttcgccaagg tactcatgcg
     5041 gttaaaaacc gttcagcagt atcaggtggt ggacgtaaac cttggcgtca aaaaggaact
     5101 ggacgtgctc gtcaaggttc tatccgctca ccacaatggc gtggtggtgg tgttgtcttt
     5161 ggaccaactc cacgttcata tggatacaaa cttccacaaa aagttcgtcg ccttgctttg
     5221 aaatcagttt actcagcaaa agttgctgaa gataaatttg tagctgtaga aagcctttca
     5281 tttgcagcac caaaaacagc tgaatttgca aaggtgcttt cagctcttag cattgataca
     5341 aaagtacttg ttcttgttga agaaggaaat gaatttgcag cactttctgc acgtaacctt
     5401 ccaaacgtag ctgtggcaac agcagcgact gcaagtgttc ttgatatcgt aaacgcagac
     5461 aaacttcttg taacgaaaga agcaatctct acaattgagg aggttcttgc ataatgaatt
     5521 tgtacgacgt aatcaaaaaa ccagttatta ctgaaaaatc aatgtatgcc cttgaagaag
     5581 gtaaatacac atttgaagtt gacacacgtg cgcacaaact gttaatcaag caagctgttg
     5641 aagctgcatt tgacggagtt aaggttgcaa gcgtcaatac tgttaacgtt aaaccaaagg
     5701 ctaagcgtgt tggtcgttac acaggtttta cttcaaaaac taaaaaggct atcatcactc
     5761 ttacagctga ttctaaagca atcgagttgt tcgcagttga agctgaataa tctaaggagg
     5821 aaataacgtg ggtattaaag tttataaacc aacgacaaat ggccgtcgta acatgacttc
     5881 tttggatttc gctgaaatca caacaagcac acctgagaaa tcattgcttg tttctcttaa
     5941 aaacaaagct ggtcgtaaca acaatggtcg cattacagtt cgtcaccaag gtggtggaca
     6001 caaacgccat taccgtttga ttgacttcaa gcgtaacaaa gatggtgttg aagcagttgt
     6061 taaaacaatc gaatacgatc caaaccgtac tgcaaacatt gcacttgtac attacactga
     6121 cggagttaag gcttacatca tcgctcctaa gggtcttgaa gtaggtcaac gtattgtttc
     6181 tggaccagat gcagatatta aggttggtaa tgcacttcca ttagtaaaca ttcctgttgg
     6241 tacagttgtt cacaacattg agcttaagcc tggtaagggt ggagagcttg tacgtgctgc
     6301 tggagcttct gctcaagtac ttggtcaaga aggcaaatac gttcttgttc gtcttcaatc
     6361 aggtgaagtt cgtatgattc ttggaacatg tcgtgcaact gttggtacag ttggtaacga
     6421 gcaacaatca cttgttaaca ttggtaaagc aggacgtagc cgttggaaag gtatccgccc
     6481 aacagttcgt ggttctgtaa tgaaccctaa cgatcaccca catggtggtg gtgaaggtaa
     6541 agcaccagtt ggacgtaaag cgccatctac tccttggggt aaaccagcgc ttggtcttaa
     6601 aacacgtaac aaaaaagcta aatctaacaa gcttcttgtt cgtcgtcgta acgaaaaata
     6661 agcggcaaat ctagcataag cttattcaat cattccgcca gctcggtaga gtttgagctt
     6721 gctctcatgc tcaagccgct gtggtacatt atttaaagga gaaaactaca aaatgggacg
     6781 tagtcttaaa aaaggacctt tcgtcgatga gcatttgatg aaaaaagttg aagctcaagc
     6841 taatgacgaa aagaaaaaag taatcaaaac ttggtcacgt cgttcaacga ttttcccaag
     6901 tttcatcgga tatacaatcg cagtttatga tggccgcaag catgtacctg tgtacattca
     6961 agaagacatg gtaggtcaca agcttggtga atttgcacca actcgtacct acaagggtca
     7021 cgcagctgac gacaagaaaa cacgtcgtta ataggaggag gacacaatgg cagaaattac
     7081 ttcagctaaa gcaatggctc gtacagtgcg tgtttcacct cgtaaaacac gtttagtact
     7141 tgatcttatc cgcggtaaga aagttgctga tgcaatcgca atcttaaaat tcactccaaa
     7201 caaagcagct cgtgttattg agaaaactct taactcagca attgctaacg cagaaaataa
     7261 ctttggtttg gaaaaagcta acttggtagt atctgaaaca tttgcaaacg aaggaccaac
     7321 aatgaaacgt ttccgtccac gtgcaaaggg ctcagcgtca ccaatcaaca agcgaacaac
     7381 tcacgttaca gtagttgtat cagaaaaata aggaggtaaa atcgtgggtc aaaaagtaca
     7441 tccaattggt atgcgtgtcg gaatcattcg tgactgggat gcaaaatggt atgctgaaaa
     7501 agaatacgcg gattaccttc atgaagatct tgcaatccgt aaattcatta acaaagaatt
     7561 ggcagaggct tcagtttcaa caattgaaat tgagcgtgct gtaaataaag ttattgtttc
     7621 acttcacact gcaaagcctg gtatggttat cggtaaaggt ggagcaaatg ttgacgctct
     7681 tcgcgctcag cttaacaaat taactggaaa acaagtacac atcaacatca tcgaaatcaa
     7741 acagcctgat cttgatgccc accttgttgg tgaaaacatt gctcgtcagc ttgagcaacg
     7801 tgttgctttc cgtcgtgctc aaaaacaagc tattcaacgt acaatgcgtg ctggagctaa
     7861 gggaatcaaa actcaagttt caggtcgctt gaacggtgca gatatcgcgc gtagcgaagg
     7921 ctactcagaa ggaactgttc ctcttcacac acttcgtgca gatattgact atgcttggga
     7981 agaagcagat actacatacg gtaaacttgg tgttaaagtt tggatttatc gtggtgaagt
     8041 tcttccagct cgcaaaaaca ctaaaggagg caaataacag atgttagtac ctaaacgtgt
     8101 taaacaccgt cgtgagtttc gtggaaaaat gcgcggtgaa gcaaaaggtg gaaaagaagt
     8161 atcattcggt gaatatggtc ttcaagctac tactagctca tggatcacta accgccaaat
     8221 cgaagctgct cgtatcgcta tgactcgtta catgaagcgt ggtggtaaag tttggattaa
     8281 aatcttccct cacaaatctt atacagctaa agctatcggg gttcgtatgg gttctggtaa
     8341 gggtgcacct gaaggttggg tagcaccagt taagcgtggc aaggttatgt ttgaggttgc
     8401 tggtgtttct gaagaaatcg ctcgtgaagc acttcgtctt gctagccaca agctaccagt
     8461 taaatgtaaa ttcgtaaaac gtgaagcaga ataaggagaa gacatgaaac ttgaagaaat
     8521 caaaaagttt gttgctgagc ttcgtggctt gtctcaagaa gagcttgcta agaaagaaaa
     8581 cgaactcaaa aaagaacttt tcgaccttcg ttttcaagct gcagcaggtc aactagatca
     8641 aactgctcgt ttgaacgaag ttaaaaaaca aattgcacgt gtaaagactg tgcaatctga
     8701 aatgaaataa tagattggga aaggagtatt ctaaataatg gaacgtaatc aacgtaaaac
     8761 ccttgttgga cgtgttgtat ctgacaagat ggacaaaaca atcactgtta tagttgaaac
     8821 aaagcgtaac cacccagtct atggtaaacg tatcaactat tctaaaaaat acaaagcaca
     8881 tgacgaaaag aaccttgcta aagaaggcga tatcgttcgt atcatggaaa ctcgtccact
     8941 ttcagctaca aaacgcttcc gtcttgtaga aatcgtggaa gaagctgtta ttatctaatc
     9001 aaactaaaag gagacaattg aaatgattca acaagaaact cgcttgaaag ttgctgataa
     9061 tagcggtgct cgtgagatct tgactatcaa ggttcttggt ggttcagggc gtaagtttgc
     9121 taacatcggt gacgtcatcg ttgcatctgt aaaacaagct actcctggtg gagcagttaa
     9181 aaagggtgat gttgttaagg ctgttattgt tcgtacaaag agtggtgctc gtcgtccaga
     9241 cggttcatac atcaaatttg atgacaatgc ggctgtcatt attcgtgatg acaagactcc
     9301 tcgtgggact cgtatctttg ggcctgttgc acgtgaattg cgtgagggtg gctacatgaa
     9361 gatcgtatca cttgcaccag aagtacttta attttaatca ttaaacaaac taagtcccct
     9421 aggctagcct agggtgccca taggggcgta agaaaataat aggagaaacc cataatgttt
     9481 gtaaaaaaag gcgacaaggt tcgcgttatt gctggtaagg acaaaggtgt tgaagctgtt
     9541 gttcttaaag cacttccaaa agtaaacaaa gttattgttg aaggcgtagc catcatcaaa
     9601 aagcatcaaa aaccaaacag cgaaaatcct caaggtgcta tcgttgaaaa agaagcacca
     9661 atccatgcat caaacgttca agttcttgat aaaaatggtg ttgctggacg cgttggttac
     9721 aagtttgtag acggcaaaaa agttcgttac aacaaaaaat caggcgaagt gcttgattaa
     9781 tcacgaagga aaggagaagc ataatggcaa atcgtttaaa agaaaaatat actaacgaag
     9841 taattcctgc gttgacagag aagtttaatt acacatcagt tatggctgtg ccaaaggttg
     9901 agaaaatcgt tcttaacatg ggtgtgggtg acgctgtatc aaacgctaaa aaccttgaaa
     9961 aagctgctgc agaattggcg cttatctcag gtcaaaaacc acttattact aaagctaaga
    10021 aatcaatcgc tggcttccgt cttcgtgaag gtgttgctat cggtgcgaag gtgacacttc
    10081 gtggcgaacg catgtacgaa ttcctagaca agctagttag cgtttcactt cctcgtgttc
    10141 gtgacttcca tggtgttcca acaaaatcat ttgatggtcg tggtaactac actcttggtg
    10201 tgaaagaaca gcttatcttc ccagaaatca actttgatga tgttgataaa gtgcgtggtc
    10261 ttgatattgt tatcgtaaca actgctaaca ctgacgaaga atcacgtgaa ttgcttaaag
    10321 gtcttggaat gccttttgca aaataatagg gggtaactaa attggctaaa aaatctatga
    10381 ttgctaaaaa caaacgtcct gcgaagtatt ctacacaagc ttacactcgt tgtgaaaaat
    10441 gtggacgtcc acattctgtt taccgcaagt ttaagctttg ccgcgtttgc ttccgcgagt
    10501 tggcttacaa aggccaaatc ccaggtgttg ttaaagcgtc ttggtaaaat gatgatgtga
    10561 gagcgttaag ctacctaagc aaaaatagga aaattgacga agagtctaaa tactctagga
    10621 aattttgcac ctaaaggtag tagcttgaac tcagttcaaa tgaacaaata atactatcag
    10681 atattatgtc tgattcgatg caaaggcaaa gtgtcaattt gaacacgggc gaaagccggt
    10741 gtcaaaaaga taaacattcc ttggaggttt tccctcctgc ggaagtttcc tattttgact
    10801 ttggctttta gcgccctttg tatcatcgat taactagcaa gtgcagcttg caaactacta
    10861 gtaagaggag aataataaaa tggttatgac tgacccaatt gcagactttt tgacacgtat
    10921 tcgtaatgct aatcaagtaa agcatgaagt gttagaagta cctgcatcaa atattaaaaa
    10981 agggattgca gaaatcctta agcgtgaagg ctttatcaaa aacgttgaag ttattgaaga
    11041 tggcaaacaa ggaattattc gcgtatttct taagtacggt caaaatggtg aacgtgtcat
    11101 cactaactta aaacgtgttt caaaaccagg tcttcgtatt tattctaagc gtgaggatgt
    11161 tccaaaggtt cttaatggac taggaattgc aattatttca acttcagaag gtcttttgac
    11221 tgataaagaa gctcgtcaaa agaacgttgg tggagaagtt atcgcatacg tttggtaatt
    11281 taagagacaa aagccgtaac gaacaatcta aaattagaaa attattgtgg cttgcttgca
    11341 aacaaaatag tttgtctatt ttagatggca gttcgtcggc tgtgctcaaa tgatgaacac
    11401 tatcaacata gcaaacgtaa aagaactaat tgaacatggg ctaaagtctg tgtgaaaaag
    11461 ataaattttt ctagaaacct tggtttcata gtaatgtttc ctattttcac tttgcctttt
    11521 acgccctaag tatcttagtt caccccgtga aaactcgtcg cgtaagcggc ctgataattt
    11581 aacaggagaa aaaattaata tgtcacgtat tggtaataag gttattatta tccctgcagg
    11641 cgttgaaatc attaacaacg acaatgttgt tactgtaaag gggcctaaag gagagctcac
    11701 tcgtgagttt aacaaaaata ttgaaatcaa agtcgaagga aacgaaatga ctcttgtacg
    11761 tcctgacgac tcaaaagaaa tgaaaacaat tcatggtaca actcgtgcaa acttgaataa
    11821 catggttgtt ggagtttcag aaggtttcaa aaaagagctt gaaatgaagg gtgtcggata
    11881 tcgtgcacag cttcaaggct ctaagcttgt tctttcagta ggtaaatctc accaagatga
    11941 ggtggaagct ccagaaggga ttacatttac tgtagctaat ccaacatcaa tttcagttga
    12001 gggtatcaac aaagaagttg ttggtcaaac tgccgcttac attcgtagcc tacgttcacc
    12061 agagccttac aaaggtaaag gtattcgtta cgttggtgag tatgtacgcc ttaaagaagg
    12121 taaaacaggt aaataatgtt cttagtggaa tatggcatag gcttgcttat gtcatgctct
    12181 acaagctcaa ttgataattt gtcggaaaga caaacttaaa tattaagagg tgaaaattgt
    12241 gatttcgaaa ccagataaaa acaaaatccg ccaaaaacgc catcgtcgcg ttcgcggtaa
    12301 actctctgga actgctgatc gcccacgttt gaacgtattc cgttctaata caggcatcta
    12361 cgctcaagtt attgatgacg tagcgggtgt aacgctcgca agtgcatcaa ctcttgataa
    12421 agaagtttct aaaggaacaa aaactgaaca agctgttgta gtcggcaaac ttgttgctga
    12481 acgtgcggtg gctaaaggta tttctgaagt ggtgtttgac cgcggtggat atctctatca
    12541 tggacgtgtt aaagctttgg ctgatgcagc tcgtgaaaac ggattgaaat tctaataggg
    12601 aggacacaaa ataatggcat ttaaagataa tgcagttgaa cttgaagaac gcgttgttgc
    12661 tattaaccgc gttacaaaag ttgttaaagg tggacgtcgt cttcgttttg cagctcttgt
    12721 agttgttggt gatggaaacg gacatgttgg attcggtact ggtaaagctc aggaagtacc
    12781 agaagctatt cgcaaggcag ttgaagctgc taaaaagagc atgattgaag tgccaatggt
    12841 tggcacaaca attcctcacg aggtttacac taactttggt ggagctaaag tattgttgaa
    12901 gccagctgta gaaggttctg gagttgctgc tggtggtgcg gtacgtgccg tcatcgaatt
    12961 agcaggtatt gctgatatta cttcaaaatc tcttggttca aacactccaa tcaacatcgt
    13021 tcgtgcaact gttgaaggat taaaacagct taaacgtgca gaagaagttg ccgcacttcg
    13081 tggcatctca gtttctgact tagcttaaga aaggggatca tcatggctca aattaaaatt
    13141 actttgacta agtctccaat cggacgtaag ccagaacaac gtaaaacggt tgttgccctt
    13201 ggacttggta aattaaactc ttcagttatc aaggaagata atgctgctat tcgtggtatg
    13261 gtgacagcaa tttctcactt ggtgacagtt gaagatgtca aataaagagt tagctagaaa
    13321 tctctgattt cttgcattag catgcagaac cggcttttgt gagttattcc tttgaatgac
    13381 aagcagtggt cggttggtgc atatagcatc aggctatgac atagcttgat catgtatagg
    13441 cgagtttcta tggagagtcc tttcccttca tagaggcgct agcattttac aaaaaaagga
    13501 gaaaaaatga aacttcatga attgaagcct gccaaaggct ctcgtaaagt ccgcaatcgt
    13561 gttggacgcg gtacttcatc aggcaatggt aaaacatctg gacgcggtca aaaaggtcaa
    13621 aaggctcgta gtggtggtgg cgtacgtcta ggctttgaag gtggacaaac acccttgttc
    13681 cgtcgtattc caaagcgtgg atttacaaat atcaacacta aagagtatgc tcttgttaac
    13741 cttgatcaat taaacgcttt tgaagatggc acagaagtaa ctccagttgt tcttaaggaa
    13801 gctggaatcg ttcgtgctga aaagtcaggc gttaaaattc ttggtaacgg cgaattgact
    13861 aaaaaattga ctgttaaagc agcgaaattt tcaaaatctg ctgaagcagc cattactgct
    13921 aagggtggtt caatagaagt catctaatga ggggatactc attatgttct taaaaatact
    13981 caaagacgca ttgaagataa agaatgttag aaataaaata ttttttacaa tctttattat
    14041 ccttatattc cgtattggaa cacatatcac tgttcctggt gtaaatgcaa aaagcttaga
    14101 gcagctgagt gagcttccct tcctaaatat gttgaacttg gtcagcggta atgcaatgag
    14161 aaacttttca gttttctcaa tgggtgttag tccctatatt acagcctcaa tcgttgttca
    14221 gctattgcag atggatattt tgccgaagtt tgttgagtgg ggaaaacaag gtgaggttgg
    14281 ccgtcgtaag ctaaaccaag cgacgcgcta tatttccctt gtcttagcct ttgctcaatc
    14341 tatcggtatt acagcgggtt ttaacacctt atcaagtgtg gccctagtca aaacaccaga
    14401 tgtaagaacc tatttactga ttggagcttt actgacaaca ggtagtgtga ttgtgacctg
    14461 gcttggtgaa cagattaccg ataaaggctt tggtaatggg gtgtctatga ttatctttgc
    14521 aggtatcatt tcctctattc caaatgctat tgcaaccatt cgtgaggatt attttgtcaa
    14581 tgtgaagtca ggtgacctac agtcatctta tatcgttgtt ggtattctca ttcttgcagt
    14641 gcttgctatc gtctttttca caacgtatgt tcagcaggcg gaatataaaa ttccaatcca
    14701 atatacaaag cttgttcagg gtgcgcctac aagctcatac cttcccttaa aagtaaatcc
    14761 agctggtgtt attcccgtta tctttgccag ctcgattaca acaattccaa gtacgattat
    14821 cccgttcttt caaaatggca gagatattcc atggttgaca actttgcaag gaatttttaa
    14881 ctatcaatct ccaacaggaa tgattgttta tgccttgtta attatcctgt tttcattctt
    14941 ctataccttt gttcaagtaa atcctgagaa aacagctgaa aatctacaga agaattcgtc
    15001 ctatattcca agtgttagac ctggacgaga aacagaagaa tttatgtcat ccttgctaaa
    15061 gaaattggca actgtgggtg ctatcttcct agcatttata tctcttgttc caattgcggc
    15121 acaacaagct cttaacctat cttctagtat tgcattaggt ggaactagct tgctgatttt
    15181 gatttcgaca ggtatcgaag gtatgaagca gcttgaaggt taccttctca agagaaaata
    15241 tgtcggattt atgaatatta cagaatagaa tatgggttga cactgtcaac cttctatttt
    15301 gtttttaaat gacaataaga tttacagagc cttggttcct atcttcttat tgccatttga
    15361 aaacaaaaac aaggaaaact aaatttccta ttatctttat gtcaaaagag gagaaaaaga
    15421 tgaatctttt aatcatgggc ttacctggtg ccggtaaggg tacacaggct gcaaagattg
    15481 ttgaaacctt tgagcttatt catatttcaa caggagatat gttccgcgct gcaatggcta
    15541 atcagactga aatgggagtt cttgcgaaat cttatatcga taagggtgat ttggtgccag
    15601 atgaggtaac caatggtatc gttaaagaac gcttagcaca agctgatatt aaagaaaagg
    15661 gatttctttt agatggctat cctcgtacca ttgagcaggc acatgcctta gatgaaacct
    15721 taaaagcatt gggacttacg ttagatggtg tgatcaacat tgaggttgac cctgcgtcac
    15781 tcattgacag gcttagcggt cgtatcatca acaaaaaaac aggggaaacc ttccataaga
    15841 tctttaaccc accagtggga gactataagg aagaggactt ttatcaacgt gaagatgata
    15901 agcctgaaac agttaagcgt cgcttagatg ttaatattgc acaaggtgag cctattatca
    15961 agcattatcg tcaagcaggc attgttcgtg acattgacgg aaacaaggac atttctgagg
    16021 tctttgctga cataaaaaag gtcatcgaaa acctgaaata aattccagaa aatcgcttgc
    16081 gaaagtgatt ttatcgtgat atactagact agtctgactt ataattgtta cctctgtgct
    16141 cagaggacat caaatcgaaa tttagggggt acttttgcgt ggcaaaagaa gacgtgattg
    16201 aaattgaagg taaagttgtc gaaactatgc caaatgcaat gtttactgtt gaattggaaa
    16261 atggacatca gattttagca accgtatcag gaaagatccg caaaaattac attcgtattt
    16321 tagtgggtga tcgtgttact gtagagatga gtccttacga cttgacacgt ggacgtatca
    16381 cataccgctt taaatagtcg aaataattgg agggattaaa acatgaaggt aagaccatcg
    16441 gttaaaccaa tttgcgaata ctgcaaggtt attcgtcgta acggtcgtgt tatggtaatt
    16501 tgtccgacaa atccaaaaca caagcaacgt caaggataag atagaaagga gaaaaaatgg
    16561 ctcgtattgc tggagttgat attccaaatg ataagcgtgt agtaatttca cttacctatg
    16621 tgtatggaat tggtcttgca acatctaaaa aaatcttagc agcagcaggt gtctctgagg
    16681 acattcgtgt taaagatttg acatcagatc aagaagacgc tatccgtcgc gaagtggata
    16741 caattaaagt tgaaggtgat cttcgtcgtg aagtaaacct aaatatcaag cgtttgatgg
    16801 aaatcggttc atatcgtgga attcgtcacc gtcgtggact tcctgtacgt ggacaaaaca
    16861 caaaaaacaa tgctcgtact cgtaaaggta aagctgttgc gattgcaggt aagaaaaaat
    16921 aaaataggag gtaaaaaaat tggctaaacc aacacgtaag cgtcgtgtga aaaagaacat
    16981 cgaatctggt gttgcacata ttcacgctac atttaataac actattgtta tgattacaga
    17041 tgtgcacggt aatgctttag catggtcatc agccggtgct cttggtttta agggttctcg
    17101 taagtcaact ccttttgctg ctcaaatggc tgcagaggct gctgcgaaat ctgcacaaga
    17161 acatggttta aaaactgttg aagttactgt aaaaggtcct ggttcaggtc gtgaatcagc
    17221 tattcgtgcc ctagctgctg ccggtcttga agtaactgcc attcgtgatg tgactcctgt
    17281 accgcataat ggtgctcgtc ctccaaaacg tcgtcgtgta taatcacagt aacaaatagt
    17341 acacaagttt cgtttcgagg ggtgaaagaa tgattgagtt tgaaaaacca ataataacaa
    17401 aaattgatga aaataaagat tacggtagat ttgtaatcga accacttgaa cgtggatatg
    17461 gtacaactct aggtaattca cttcgtcgtg tactcttgtc ttcacttcca ggtgcagctg
    17521 ttacatcaat cagaattgat ggagtactac acgaatttga tacaatccca ggtgtacgtg
    17581 aagatgtcat gcaaattatc cttaatgtta agggacttgc tgtgaaatca tacgtcgaag
    17641 acgaaaagat tatcgagctt gatgtagaag gtccagcaga ggtaacagct ggagatattc
    17701 tcacagatag cgatatcgaa cttgttaacc ctgatcatta tctttttact attgctgatg
    17761 gttatacatt gaaggcttca atgactgtcg ctaaaaaacg cggctatgta ccagcagagg
    17821 gtaataaaaa agatgatgca cctgtgggga cgttggcagt agattcaatc tatacgccag
    17881 taaaaaaggt taattatcaa gttgagcctg ctcgtgtagg tagtaatgac ggctttgata
    17941 aattgactat tgaaatcatg acaaacggaa caattattcc cgaagatgcc ttaggtttat
    18001 ctgctcgagt tttaatcgaa cacttgaatt tatttactga tttaacagat gttgcaaagg
    18061 caactgaagt gatgaaggaa gctgaaaaag tgaacgatga aaaggtactt gatcgcacta
    18121 ttgaggaact tgatttgtcc gtacgctcat ataactgctt gaaacgtgcc ggtattaata
    18181 ctgtcttcga tttaacagaa aaatctgagc ctgaaatgat gaaggtccgt aaccttggac
    18241 gtaagagtct tgaggaagta aaggtcaagc ttgctgactt aggtttggga ctaaaaaacg
    18301 ataaataaca taggaggata aaatggctta ccgtaaacta ggacgcacta gctcacaacg
    18361 taaagcaatg cttcgtgact taacgacaga tcttttgatt aacgaatcaa ttgtaacgac
    18421 agaagcacgt gcaaaggaaa tccgtaaaac agttgaaaaa atgattactc ttggtaaacg
    18481 tggtgatctt catgctcgtc gccaagcagc tgcatacgtt cgtaacgaaa tcgcatcaga
    18541 aaactatgat gaagctactg ataaatacac atcaacaaca gctcttcaaa aacttttctc
    18601 tgaaattgcg cctcgttatg cagaacgcaa cggtggatac actcgtatcc ttaaaacaga
    18661 accacgccgc ggagatgctg ctccaatggc gattattgaa ttagtttaat ttttatcaat
    18721 tttgttgagt gttatgatga tggagcagtt cctttaagct gttcttagtc tagctctggt
    18781 ctaccgctag gacctttcct agcggtaaca ctcaccatgt tgagaataag taacgcttgt
    18841 ttacgaaagg tctctaagct gtaggtgccc ttcgtaagca ggcgttttgt tgtgactcca
    18901 tgttaactgt agtagatgac taatatctaa tatctagaga ggatcagctt ggtgctctct
    18961 tttctgatat taaaagcatt gggaatcttg gttttgaagt tcttaaagct cctaaagcca
    19021 aagtctttcg cttgatgtct ttggtcatct tgttagtggt ctccggctta gcattggaat
    19081 aaggtagttc aaagcattgg tgatgtaaga tctatacttc ctgaaggtct tgaaaaccgt
    19141 tttgaaggtg tgattgacct gtagcgggag tagattagat caatggcgtt tggctgcttt
    19201 gaaaatttag gtgacaattg tttttgtatc tttgtttaaa aatggtataa tattaaaaca
    19261 ttaaacaaaa tgtacataaa aaagccatat aaaagaatga tattaagata atgtgatcaa
    19321 tagttttaga aaatgaatgt gtaaggttaa ggtatgcccc cttgatataa tgctagtttt
    19381 acgaagaggc attctgtaca gacataatgc actcttacaa atgatacggt aattgctcaa
    19441 caaggcgcaa cagccttggc aaatgtaata tttgccttag ctagcagcga attagttacg
    19501 cttgatacat agacaagggt ttctggcata cagcagcaga tggtgtgcct gtctcagaga
    19561 gtggctgctt ggcttatcct attcatgttt taaaacttac aggaggtgtt atgtggcctt
    19621 tggtcgatgg atatttagct aggtgaacag ctattagctg taaatatgag gtaggagctt
    19681 tagtttgcat gatgttaaat gaattgaaac agacttagga aagcttggct tagcaactat
    19741 cacgcaagtt cttaacaacg ataaagatcg tatgggaaaa tatgatcaag catcaacgga
    19801 catgagatgt gttttatgaa gaaaccatta tacttttata agacttattt agttgttttt
    19861 ctttgcggac ttgtttgagg agtagtctac ataggcaata ggctcaggct tacagcactt
    19921 aggagacatt agagcatgag aagcactaac tggctagtga tagaaaagta atagcacagt
    19981 gtttttataa ctaacaagag gagtagacat tctatgagta ttgacatgta tttgagctta
    20041 tctgaagagc aggcacagag tgtagaggct gtcttagcta ggcgacaaac agcctatcaa
    20101 tccttacagg agaccttgat ccaattgatt tctaacagtc ctgatttatc agggcggacc
    20161 tatgattctg ctaaggctta tagtagtcaa gtgctaattc ctttgttaaa ggggtgtatg
    20221 cttttagatg aggcgattat aacagcctgt aagaggctac ctagtgagta ccgtagtcag
    20281 gtagaccaaa ttgatttgaa ggagagtgat ctggttgagc gtattgccca gttcgatcat
    20341 gtgattggtc ggtacatgga tttgattagt attgaataca gtagagagga gcctagctat
    20401 tcttatatct ctcatttaag atcagctgag cagctccatc gggccgttaa gcggcgtctt
    20461 gaggagatat tgcgaaggct aaggcatttt gataccaact cagttcacct tttttcgact
    20521 attcagactt tggcagcagc ggtacaaata ggcatgcgtc aagctaggac ctcgtggcat
    20581 gcaggaagtc aggtatttgt gatttcagag gatatggcat gggccgatac gattaattct
    20641 aagtggtcaa aaagtaaagg gttaagctat cttagtgatt atgtttacga cccagatgtg
    20701 ctctctaaga gagcagctat taatcactct tggattaaaa caggctatac tatgtctaaa
    20761 aattttggca aagctgtttc aaaagattat acaaaagcaa gctttttgag ctatggtaag
    20821 gcagccaagg cgactggctg gacttctatg gcagtagata ctggaataac tagtgtaagg
    20881 gaatacaata agaaaaatag tagagcctat ggcagtgagg gcaaggcgct tattcatgct
    20941 agtgtggctc aaatcaagag catgggacct atagaagggg cgataattgg cagtaaagct
    21001 ggaccttggg gagcattaat ggggtttgtt acaggaggca ttaatgttac ttggggagta
    21061 gtgcatccag agtctaagga caacatgttt ttatggatac aagataaaat ggatgatgtt
    21121 tacgattcga ttgttcagac agatcttggc aaagggacgc accatgctaa agaaagtgtc
    21181 aaaggtcata tcggtcgagc tattgtaagg acatgggact ttgtcagtca atcatttggt
    21241 aaaggagtgg gctatgacat ttaaagatca gctttttagt gggacgtttg agcaatcaaa
    21301 aaagattgtg tctaaaagta tattgacaga agaaggtgcg cagattggag tattctcatc
    21361 tatgagtcta tggaagagaa taacaggctt gatgatgttg ccattatttg ctatttcata
    21421 tggagtagga gttgtgttac ctgaacactt tcaataatca acagaaggag ttcaagctat
    21481 ttcattggct gcaatagaga ttattgccag attaggacag ttcagtcgat actttatcat
    21541 ttgttttatt tgtatgtctg ttggattaat tattagtaat atccttccaa agcctaacta
    21601 ggcttatcaa ttattatatg gcaatgctac tcttattata cttagtatta caactattat
    21661 ctcagccttc cctttaactg ctggccttac aattgcagct tttggctgga tcggtttttt
    21721 gcttcagcta ttgctttgcc tttatttgtg gaaggtttgt gtcatagata agtgtcaaca
    21781 gctacgcaca gcaatttatc aagaaagcac catagcacct gattggggca gtaagctagt
    21841 aagctttatt aagtcttatg gtggtatctt attaggcctc tctgttctca accgctggac
    21901 tctcaatcta ggagagctag tcaaggaaag ccctggtttg ttgagttttc tgtacggctg
    21961 gatttttcta ttgttcatgt ttttgatgct atttgcactg ggtcaagcgt taaaaaatac
    22021 catcatagcc tattattttt ttagatatca aaaagaatac cgcaagcatt ttaatataag
    22081 cgatgagcag tggtacggta aatggcgttt aaaaatatta ttaaaataaa cgatataagg
    22141 agtaatcata tgcaaaaaga attattaccg ttaggaagtg ttgtctatct agagggagca
    22201 acaagcaagc taatgattgt cggacgtggt cctatatttg aatctaatgg ccaaaatgtc
    22261 tacagtgatt atgttggagt aatgtatcca gaagggatca atccagaaga cgcgattttt
    22321 ttcaaccatg aagatattgc aaaaacagtc tttgaaggct tcaaggacga agaagaacaa
    22381 cgctttttag aagtgtattc tgattgggag agtactttag aaatttccaa aataaagcta
    22441 tagatgaact gtagcagata tatttgtcag tagattgtca tgattatatt gaaagattat
    22501 gactttctct ggcttaaata cctctaaagt tccaaagttt agaaaaggct ttaaaatgag
    22561 tgttataata gcatttatgc tcattaaata aaggtagcat ttcaatagaa tcggtaaaaa
    22621 aa
//
LOCUS       DARYLD010000035        21156 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYLD010000035 DARYLD010000000
VERSION     DARYLD010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21156
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(171..461)
                     /locus_tag="TU651_001221"
     CDS             complement(171..461)
                     /locus_tag="TU651_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897226.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TU651_001222"
     CDS             complement(442..834)
                     /locus_tag="TU651_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897227.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TU651_001223"
     CDS             complement(816..2105)
                     /locus_tag="TU651_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897228.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..2538)
                     /locus_tag="TU651_001224"
     CDS             complement(2107..2538)
                     /locus_tag="TU651_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897229.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            2877..2963
                     /locus_tag="TU651_001225"
     CDS             2877..2963
                     /locus_tag="TU651_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0897230.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(3311..5752)
                     /locus_tag="TU651_001226"
     CDS             complement(3311..5752)
                     /locus_tag="TU651_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL0897231.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(5752..6213)
                     /locus_tag="TU651_001227"
     CDS             complement(5752..6213)
                     /locus_tag="TU651_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL0897232.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(6383..6586)
                     /locus_tag="TU651_001228"
     CDS             complement(6383..6586)
                     /locus_tag="TU651_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL0897233.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            complement(6799..6869)
                     /locus_tag="TU651_001229"
     tRNA            complement(6799..6869)
                     /locus_tag="TU651_001229"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6835..6837),aa:Cys,seq:gca)
     gene            7217..7777
                     /gene="ahpC"
                     /locus_tag="TU651_001230"
     CDS             7217..7777
                     /gene="ahpC"
                     /locus_tag="TU651_001230"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL0897234.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            7798..9330
                     /gene="ahpF"
                     /locus_tag="TU651_001231"
     CDS             7798..9330
                     /gene="ahpF"
                     /locus_tag="TU651_001231"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL0897235.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            9791..10561
                     /gene="rpsB"
                     /locus_tag="TU651_001232"
     CDS             9791..10561
                     /gene="rpsB"
                     /locus_tag="TU651_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL0897236.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            10729..11769
                     /locus_tag="TU651_001233"
     CDS             10729..11769
                     /locus_tag="TU651_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL0897237.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(11969..13864)
                     /locus_tag="TU651_001234"
     CDS             complement(11969..13864)
                     /locus_tag="TU651_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL0897238.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(14416..15348)
                     /locus_tag="TU651_001235"
     CDS             complement(14416..15348)
                     /locus_tag="TU651_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL0897239.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            complement(15345..16202)
                     /locus_tag="TU651_001236"
     CDS             complement(15345..16202)
                     /locus_tag="TU651_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL0897240.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            complement(16205..17548)
                     /locus_tag="TU651_001237"
     CDS             complement(16205..17548)
                     /locus_tag="TU651_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL0897241.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            complement(17561..17848)
                     /locus_tag="TU651_001238"
     CDS             complement(17561..17848)
                     /locus_tag="TU651_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0897242.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            complement(17850..19892)
                     /locus_tag="TU651_001239"
     CDS             complement(17850..19892)
                     /locus_tag="TU651_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL0897243.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            20415..21005
                     /locus_tag="TU651_001240"
     CDS             20415..21005
                     /locus_tag="TU651_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897244.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
BASE COUNT         6359 a         4835 c         4044 g         5918 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctattaga atcattaaag caataaaagc
     2521 tttggtcgac tttttcatga aagttctcct ttcaatttct aataatagta tacaataaat
     2581 cagaagtcat agaataacca tattcaattt ttatgtcgta ttcgataaaa aatataccat
     2641 ctcaacaaac aatcgcttaa aaacgatttt agggtatatt tcttccctgc aagcaaagga
     2701 cacaaaaaag ccatctgaat tttcaacatc agacagctat ttcgtatgac tatggtataa
     2761 tggtttctgc agaaaagtta aggcggtggc tctaatttct gaaaggtggt ggtgcttatg
     2821 actgtaagtg ctaaaatcca aagagaaagg agcgaatatt gtccgtttac gaggcaatgc
     2881 aactcatgct tgggttcggt agttttctac tttcactcat tggcttagtt gttattatcg
     2941 taaaaatgag caataaaaaa taaccgtcta actttagcga gtaacggtta ttttttaact
     3001 aaaaacaagc taccgtctta aacggttctg cattgggtag ttgttttgag caactgtcct
     3061 ttttctattt tcattatatc tcagctaaga aaaatagtca aatgagatac tattttggca
     3121 gctaaattgg tagctaaatc ttcaaaatac ctatttttcg ctaaattcga ttaaaattaa
     3181 atcctatctg tctgctacgc tttaaactct cactctagta cttcatcacc atacgacaaa
     3241 aagagcctga gaaacttttt gtctcagact ctctcaaagc tcttagctta atatcaagca
     3301 aagtcatgca ttaagcgata tcaaaagcta gttttccacg tgatacacca atcttgaggc
     3361 tttgaccgct tgataactct cctgacagca ttaattctgc taacctgtcc tcaacctctg
     3421 tttgcaaggt gcgacgaagt gggcgagcgc ccatttcaac atcgtaacca gcttcagaca
     3481 agtacttgag agctgatggc tggaacttaa ggctaatatg cttttctgcc aaggctgcaa
     3541 tcagcggctt aaccataatt ttcaccacat cacgcatgtt ttcctgtgtt aggctatgga
     3601 agaccacctt ttcatcaatt ctgttgataa attcaggccg ataagccttt ttcaattcct
     3661 ctaaaatacg cttttccatt gcttgatggt catgaccgat cgctttagcg ccaaatccaa
     3721 ccgtcttatc atctcttaga gcagttgctc ctaggttgct cgtcatgata ataatcgtgt
     3781 ttgaaaaatc aaccttacat ccacgactat ctgttaacat accatcatca aggacctgca
     3841 gcaggatatt aaagatgtct gggtgagcct tttcaacctc atcaaaaaga agaacggcat
     3901 aaggcttatt tctaaccttt tcggttagct ctcctccctc atcatagcca acatagccag
     3961 gaggagcccc attaagacgg gaggctgcaa atttttccat gtactcagac atatcaaaac
     4021 gaataagggc tgactcatca tcaaagagta attcggccaa ggcctttgct agctctgttt
     4081 ttccgacacc agttggacca agaaacataa aggagccaat cggacgcctg cctgtgcgaa
     4141 tgcctgactg gttacgacga atggctcgtg caatagcaga aacagccatt tcctgaccaa
     4201 caacacgctt atgcaattcc ttttccagat tcaggtattt tttactatcc gcctgagtta
     4261 gtttttctag gggaatacct gatagcttgc ttaaggtgtg taacatatca tcttcagtaa
     4321 ctgctgttgg ttttagcttt ggttgcttat cctctttgac taaaagggct gacaccttgc
     4381 tcatatcacc atcaagcagg gcttgatcaa gcggtgttat aaagtcaggc tgcgtctttt
     4441 taaccatact ttgcaccatc gcactggctt catcaagcag atcaatcgct gagtctggaa
     4501 gctgcttact tgtcaaatag cgccgagcca gcttcacagc agtatggaca gctgtatcag
     4561 agattgttac attatggtac tgttcatagg aaggcttcaa gccaagcaaa atctgataag
     4621 cgtcctcaac actaggctcc tcaatcaata tcttggcaaa gcgacgagaa agggctgcgt
     4681 ccttttcaat gtgcttttga tattcctctt gagttgtagc gccaaccata tgcagggtac
     4741 cgcgagaaag ggctggcttt agaatattag cggcatcaag tgtgctgtca ataccacttc
     4801 ctgatcccat aatggtatgt agctcatcga caaacaaaat gatcttacca tctgcttcaa
     4861 tatcgtcaat gagttgattc atgcgctctt caaaatcccc acgaaaacgg gtacctgcaa
     4921 ccacactcat catgtcaagc tccaagacac gcatgtcttg taattcataa ggaatggctc
     4981 cattagcaat tcgctgcgct aagccataag ctagagcagt ttttccgaca cccgcatcac
     5041 caacaagaac aggattattt ttcgtcttac gacaaagcac ctgaaccata cgtgacacct
     5101 ctttttctcg tccgatgact ggctctaata agccctgtct tgccatctct gtcaggtctc
     5161 ttgtaaagtc tgatagctca ccagctgtac tctgtggctt catcatttca gaaaaggtgc
     5221 ctactgattt actcttttta ggcttacgca actcatgaat cgccttaata gtttccttgc
     5281 tatagccggc atttagctca atagccttac gtaaatccgc aaacctaggc tctcccttgc
     5341 cagaatcctt gagcctgtag cctgccaatt ctaacagacg actggccata atatccggat
     5401 tgagcaaaat agcaaagagt acatgctctg agccaacctc atgctcattg ataacctgac
     5461 agatagcatg agcaaatgct agtatttctg ataaggcctt ggattgtggc ttgaattgga
     5521 cagaagtcac ctctttggga ctttttccca tggctaaaat agcagcagcc tcatactctt
     5581 cagccctaat ctttcgttca aattcgctta acaccatggc cgctaaggaa tggtcaacag
     5641 ctaccatagc taataaaata tgccaggtct caaggtaagg actatcaaag cgctctgctt
     5701 gaaattgagc ctgattaaaa atgtcttgca tctttaatga ataaatcatc actaattgct
     5761 tccctttcta tcaattcgtt gcaataggcg ataaagcata cgagcacgaa tttctggtgc
     5821 ttgatgtccc aaaacatcat tagaagctac agctaagata atgtttcctt cgcgctctgt
     5881 taacagttgc tcatcaaaaa gcagctgaat cgaatctgta aaggcctgct cgcttaaaca
     5941 atcatcaata gaagcgatca acgtaccaat caggtggtgc ttatccgaaa aatgaacctt
     6001 agcaatacga atgtagccac caccaccacg cttactttct acctcatagc ctctgctttc
     6061 tgtaaaacgg gtcttgatca cataattaat ctggcttggt actacttgaa aggaatccgc
     6121 cagcatggag cgcttgatct ctgcgattcc tgattgggct aacaattctt tgatatattc
     6181 ttcgatacta tcggaagtat tttttgttgg catgccgtca ctcctttgct aaaacgattc
     6241 atttgctgct ttaagccttt atttgactaa aactgactaa cattatatca aatagcagtc
     6301 actaaaagca aatggaaatc actagaatgt aaaaggacag gtgctatcaa caacacccat
     6361 cccctattat ctgctcacta gattaagaca atttagtgat atttactgcc tgaggaccgc
     6421 gctgtccgtc ttcaacatca aacgtcaccc tttgtccctc gtctaacgat ctaaagccgt
     6481 cagactggat tgctgaaaaa tgtgcaaaaa catcttgacc attttcagtt gaaataaagc
     6541 caaagccctt ttcagcatta aaccacttga ctgtaccttg tgccatagtc atccacttcc
     6601 tttctataac gcatttgtaa acatagagag aaataaagat gccaaaacac aactactaat
     6661 tcaaaaacta atttactcgc tcagtgtaac acgaatggca gccactgtca acacataccc
     6721 ctcacaatga cagcttttct actccacctg ctaaaatgta aaaaagcaaa gtcatgctga
     6781 ccttgcttta acaatctaag gcggtagacg gatttgaacc gacgatcaag cttttgcaga
     6841 gccgtgcctt accacttggc tataccgcca taacaagaac tattttaccc tagttgatag
     6901 cattcgtcaa gataaaaata gcagctattt tttagcaggc tgctcctttt ttcggtttat
     6961 gttatttttt agagtttaaa tcagaaaatc atttttaata atattaaaat tatttcaaaa
     7021 acttattttc aagaatcttt gatattatca gagttttcta ttatttagaa tagttttaaa
     7081 cagtgtgact aaattcacat atgaaattgt tagaaaagaa catcaaaaac cttgataaat
     7141 ctagggttta caagtggaca gataagattt cttagcttat aatacaggta tcaaatgtaa
     7201 aaaaggagga catgacatgt ctttagtagg aaaggaaatt gctgaatttt cagcccaagc
     7261 ttttcacaat ggaaaattta tcactgtaac taatgaggat cttaaaggga aatgggcagt
     7321 tgtttgcttc tacccagcag acttttcttt tgtttgccca acagagctag gtgaccttca
     7381 agagcaatat gaaatactaa aatctttagg tgttgaggtt tattctgtat ctactgatac
     7441 acactttgtt cataaggcat ggcacgatga ttcagatgtt gtcggaacaa tcacttaccc
     7501 aatgattggt gacccatcac atgctatttc acaagccttt gatgttcttg gtgaggatgg
     7561 acttgctcaa cgcggtactt tcattattga tccagatggt gttatccaaa tgatggaaat
     7621 caatgctgat ggtatcggac gtgatgcaag cagcttgatt gataagattc gtgctgctca
     7681 gtacgttcgt aagcacccag gtgaagtatg cccagccaaa tggaaagaag gggctgaaac
     7741 actaacacct agccttgacc ttgtcggcaa aatttaagca ggcaaaggag aaaagctatg
     7801 gcattaagtc ctgatattaa agagcagctt gctcaatacc ttaatctttt ggaatctgac
     7861 ttagtcctac aagcttatct tggtagtgac gatagctcac aaaaggtcaa ggacttcatt
     7921 gaagaaattg ctgccatgtc agaccgtatc actgttgagg agactaccct aacacgtcaa
     7981 ccaagcttta agattaccca aaaaggtcaa gacagcggag tgatctttgc tggactgcct
     8041 ctaggtcacg agtttgcctc ctttatcctt gctctattac aggtttcagg acgtgcacca
     8101 aagattgagc aggatattat tgaccgcatc agggctattg accgtccttt aagctttgaa
     8161 acctatgtca gcttaacgtg tcataattgc ccagatgtgg tccaagcctt gaacattatg
     8221 gctgttctta ataagaacat ttcacatact atggttgagg gtggtatgtt ccaagaggaa
     8281 gtcaaggcaa agggcatcat gtctgtgcca actgtctttt tgaatggaga agaattcacc
     8341 tctggtcgcg ccactattga gcagctgctt gagcaaatcg caggacctct atctaaggag
     8401 gcctttgctg ataaaggagt ctatgacgtc cttgtcattg gtggaggacc tgcaggaaat
     8461 agtgctgcca tctatgctgc tcgtaaaggc ttaaatacag gtcttttggc tgagaccttt
     8521 ggtggtcaag tcatggaaac tgtaggtatc gaaaacatga taggaaccct gtatacagag
     8581 ggaccaaagc ttatggccca ggttgaggag catactaaat cctatgatgt tgacatcatc
     8641 aaagcccagc tggctacttc gattgagaaa aaagaccttg ttgaggttac tcttgctaat
     8701 ggcgctgtct tgaaggctaa aacagctatt ctagcgcttg gtgcaaaatg gcgcagtatc
     8761 aatgttcctg gcgaaaatga gtttaaaaat aaaggagtaa cctactgccc acactgtgac
     8821 ggtcctctct ttgaagataa aaacgttgct gttatcggtg gtggtaactc tggacttgag
     8881 gctgcacttg atttagctgg cttagctaag catgtctatg ttcttgagtt cttacctgag
     8941 cttaaggccg acaaggtgct acaggatcgc gctgctaaaa cagacaatat gactattcta
     9001 aaaaatgttg ctacaaagga tattgttggg gacgatcatg tcacagggct taactatatc
     9061 gagcgtgaca gcaatcaaga aaagcatctt gaccttgaag gagtctttgt acagattggc
     9121 ttggtgccaa atacagcttg gctcaaagac agcggtatca gcttaaccga tcgtggcgag
     9181 attattgttg ataaatatgg ttcaaccaat attccaggta tctttgccgc aggcgactgt
     9241 acagattcag cctacaaaca aattattatt tctatggggt caggtgctac tgctgctatt
     9301 ggagcatttg attacctgat tcgtcagtaa gttagcaaaa aaccaaggta actgtttacc
     9361 ctggtttttg ctttttagag gcctaataaa cagcaaggct gatagatcaa gcatttgggg
     9421 tacgccaaat gcttgaagaa acttatgttc tctgatatct tttcatgatt catgtgttct
     9481 ttttcagaaa gattgatagt aaaactaagc tgcgcttgaa aaatggatcg tgtcaaaacg
     9541 tcaacatatc aaaaatgcat tgaaaacatg catatggtta gaaaataatg gcatgcattt
     9601 tcctcatgcg tacgacgtgg gttttagtgt atttaggctt gctatgacta gctttttttg
     9661 gtatactgtt gtagttgtgc agacaacaaa tactcatctt agatcgattg tgattctgtt
     9721 gccatcaggt ggagttgcaa gccgacgtct aagagaggaa aaaaacattt ctataaagga
     9781 gaaactactc atggcagtaa tttcaatgaa acaacttctt gaggctggtg ttcactttgg
     9841 tcaccaaact cgtcgctgga accctaagat ggctaaatac atcttcacag agcgtaacgg
     9901 tatccacgtt atcgacttgc aacaaactgt aaaattagct gatcaagctt acgagtttgt
     9961 tcgtgatgca gcagctaatg acgctgttat cttgtttgtt ggtactaaaa agcaagctgc
    10021 tgaagcagtt gctgacgaag ctactcgtgc aggtcaatac ttcatcaacc accgctggtt
    10081 gggtggaact cttacaaact ggggaactat ccaaaagcgt atcgctcgtt tgaaagaaat
    10141 caaacgcatg gaagaagaag gaacctttga ggttcttcct aagaaagagg ttgcacttct
    10201 taacaagcaa cgcgcacgtc ttgaaaaatt cttaggtggt attgaggata tgcctcgtat
    10261 cccagatgtg atgtacgttg ttgacccaca caaagaacaa atcgctgtta aagaagctaa
    10321 gaagcttggt attccagttg tggcaatggt tgatacaaat gctgacccag atgacattga
    10381 tgtgatcatt ccagctaacg acgacgctat ccgcgctgtc aaattaatca ctgctaaatt
    10441 ggctgatgct gttatcgaag gccgtcaagg tgaagacgca gaggttgcat ttgaagctga
    10501 tactcaagca gagtcaatcg aagaaatcgt tgaggttgtt gaaggttcaa acgaagctta
    10561 agtcaggctt attgaactag gatagcttct tgctattcat aacatggtct aacggggcaa
    10621 agcattccgc tctatctcgt tattttttaa gtaagaaaac ccagcaggtc aaaggctctg
    10681 ctaaagcgag ctttaagagg accgattcta attttggagg aaataaaaat ggcagaaatt
    10741 acagctaagc ttgtaaaaga attgcgtgaa aaatctggtg ccggcgttat ggacgctaaa
    10801 aaagcacttg ttgaaacaga tggcgacatg gaaaaggcta ttgagcttct tcgtgaaaag
    10861 ggtatggcaa aggccgctaa aaaagctgac cgcgttgctg ctgaaggctt gacaggtgtt
    10921 tatgttaatg gtaacgttgc tgctgttgtt gaggtcaatg ctgaaactga cttcgttgcc
    10981 aaaaacgctc aattcgttga attggtaaac gcaactgcaa aggctatcgc agaaggtaag
    11041 ccagctaata acgacgaagc acttgctctt atcatgcctt ctggtgaaac acttgctgat
    11101 gcttatgtca atgcaacagc tacaatcggt gaaaaaatct cattccgtcg ctttgcccta
    11161 gttgaaaaaa ctgatgacca acactttggc gcttaccaac acaatggcgg ccgtattggc
    11221 gttatcactg ttgttgaagg cggagacgaa gcacttgcca agcaagtatc aatgcacgtc
    11281 gcagctatga agccaactgt tttatcatac actgagcttg acccacaatt tatcaaggac
    11341 gagttggcac aattgaacca cgctattgag cttgacaatg aatcacgtgc aatggttaac
    11401 aagccagcac ttccattctt gaaatatggt tcaaaggctc aattatcagc tgacgtgatt
    11461 gcgcaagctg aagaagacat caaggctgag cttgctgctg aaggtaagcc tgaaaagatc
    11521 tgggacaaaa ttatcccagg taagatggat cgcttcatgc ttgataacac taaggttgac
    11581 caagcctata ctcttcttgc tcaggtttac atcatggacg acagcaaaac ggttgaagca
    11641 taccttgact cagtcaatgc taaagcgatt agctttgctc gctttgaagt cggtgaaggt
    11701 attgagaaaa aagctaacga ctttgaatca gaggttgctg ctacaatggc agctgcgctt
    11761 aacaactagt ctaatcataa gtcataagat tgaggacagc ttttaagagc tatcttcaat
    11821 ctttttttac gcctaaaaaa agagcttttc gagcctatcc aacacaaaaa gactaagaga
    11881 agcatgcctt cctccacaag ctagactata cgttctaacg ataggagggc cgtacaaagc
    11941 ctcttagtct ttttttaatg agcaatgatt accaaataat cacacgatcc tctggagcac
    12001 gccacattgg atcaccttct ttaatgttaa attcttggtg gaattcatca aagtttgtca
    12061 aggtcacatt agtacgccat tgaccaggtg cgtggacgtc aatacttgcc atcatttgca
    12121 tgaattcctc acgcgccttc atacgccaga tggtggcaaa gttgataaag aaatctctgg
    12181 cagaaaaatc tggctctgac tgagctgcct ctaaggcaca ggcaacacca cctaggtcag
    12241 caacattttc agacactgtt aatttaccat tgactttagc accataggag tcaaggccat
    12301 caaattgctc tacaatttta tcggtacgct ccttgaaggc ggcataatcc tcgtctgtcc
    12361 accaattctt taggctacca tgctcatcaa aggaagcacc gttggtatca aaggcatgcg
    12421 aaatttcatg agcaataaca gcaccgatac caccataatt agctgatgag ctttgactca
    12481 acgaataaaa cggcgcctgc agaatagctg ctgggaacac aatttggttt tgctgtgggt
    12541 cataataagc attaaccatg ttggcaggca tgtgccattc actacgatcc acaggcttat
    12601 tccacttgct ccatgaatga gcaattgaaa ttttggctaa attctgagca ttttcaacaa
    12661 gtgatagctt atcatcgatg acctttttag cataggtttc tggtaatttt tccggatagc
    12721 caatgtgtgg ggtgataaca tttagctttg taatggcttt ctcacgtgtt gctggtgcaa
    12781 gccaatccgc agtttcaaga cgagatttat aaacctcaat catcttagct accttgtgtt
    12841 caacatcagc cttagcctct ggtgaaaatt tttcaccagc ataccaaagc ccaagagctt
    12901 gattaaatgg tccttgtgct aagtaatagg ctgctttttt cttgtccata gcctgtggag
    12961 ttcctgacaa ggcacgactg taaactcctg atagcacacg aatctcgtca gtcaaataag
    13021 catgataagc acctgctgct gtaagcacta gccaggcttt tagcagctcc caattcttct
    13081 cagaataata gtcagctgca aattctgtcc agaaccgctc ctctggcaca acaaccttgt
    13141 ctggtacttc acctaaaatc acagtaaata tattatctaa aggcaattct ggcactagct
    13201 tggtaaactc ggcccagtca taagggtggt aaagcttggc atactctgaa tattcctcac
    13261 gagaaaggac ataatctgcc agctgtttat caagcgtgat aaccttatcc agcaagtcct
    13321 taacctcttc atgtgaaaag ccaaatttag gcaatagctc ctcttgcatg ccacgccaga
    13381 tagcaagcag ctctttgcct ttgtcattgt ctttggcata gtaagtggta tctggcagga
    13441 taagacctgg tgcctctgcc caaaggacat ttaactgagc attcataaag tctggtgcta
    13501 cactaaatgg aaactgattt ggttttccat ttagctcata atcagccacc ttgctagcaa
    13561 actcggcaaa agatcctaag gccttgtatt cttcaattaa gtccaaggct ggcgctacgc
    13621 ccacctgatc acgcttgtca taatctgcaa ccaagcggtg aaacttgaca aagttttcta
    13681 atatagcgtc attgggaaca tgctcaccag ccaaccaagc atctgttgtg gtcagcatta
    13741 agtcctcaat ctcatctgct aggtctgaaa agccccctgt acgaggctta tcgtctggga
    13801 taacagctgt ttctgcccat tgaccattga cggcttgata aaaatcttct tgatatgttg
    13861 tcatgaattg ctcctttttt aaattaaacc attatgttag gactagcttt tactcctcat
    13921 aatgtaatct cttacatttt accaaaaaat cgttcaaaat actcgtttta tattaacttt
    13981 ctgttcaaaa ataagctcat tcttcgtatc gcatggcata gatagtaaac gcttagctgc
    14041 tttggtcctt ttatcagtaa gattaatcat aaaaactgaa caatcactaa gaaatcaaac
    14101 gattcttctc cagcttcatg aaaacagccc tcacaatatg ccaaaaactc agcagtaata
    14161 gcaaaaggcc ctatcagtcc tgacaaaaga attgcacccc aaaggtgaag ataaaaccta
    14221 aagcttaaga actttttcta tgacattaaa attagaaggt gaaatcaaga gttatcaatc
    14281 attatttcac gcctacagag tgaaagggac tgaaagcgca taactaaaag gactgaaccc
    14341 tgtttcatac aaagctcaat cctaatctat aaggtccagc tttttgggtg tggtacacct
    14401 gataggcttt tttagctaat ctgccgctaa aatcctcaaa acctgctgct caatagctgc
    14461 tggcgtcagc tggtattcct ctaatagata atccatctgt ccgacctgac cgaaacgttc
    14521 gtccaccccc atacggtaaa ctggagtatt actttcctga gccagtagct cacagatagc
    14581 actcccaagc ccaccgatac gattatgatt ttcaacggtt agaacaggac tgcctgtaag
    14641 tagacccttt agctcatcgg ccagtggctt taccctgaaa acatcaatca caccgataga
    14701 gtagccctgc tctgccattt tatcggctac ctctaagcac cttttgacca tgatccctga
    14761 gcaagccagc acaaggtctt ttccttgacg caataggcaa tagccattag aaaagtcctc
    14821 atgcccttga taaatagcct ctggcttttt acgaatggtt cgaatgtatt ttaggccatc
    14881 gagtgatagg gtttccttta aaacagcttt aaattgaacg tcatcactga cctcataaac
    14941 aatagccctt ggaatcaggc gcagcagtcc cagatcctca aagggcatat gggtgccgcc
    15001 attcatttcc gcactaactc cggcatcaga gccaataacc gttgcgccta gctgggcata
    15061 ggctaatgaa agaaacagct gatcaaacac acgacgtgag gcaaagggac caaaggtgtg
    15121 taggtaaggc ttatagcctt taatcgccag gcctgctgcc agaccgacca tttctgcttc
    15181 cataatgcct acattaatat agcgcttgcc aaacacctga tccaaatggt tggtggccat
    15241 tgagcttgat aaatctgcct ctaagacgac tacctcaggg tgctcttggt tggctgcaat
    15301 gaggaaatct cggtaaacat gacgcatttc ttgacttgct cgagtcatct tgtcacctcc
    15361 aaactagctc gtagctttct gacagcggca gcaagcatct ccttttcggc tgctgttggt
    15421 cttagatggt ggttagctgc cattgactct agctggctaa caccctgacc cttgacggta
    15481 tctaagacga tacacttggg cttatgactt gatgacgcct gcaaagccct gatggcttca
    15541 aaaatagcct gaacatccct accatctaca cgtaagcttt caaagccaaa tgccgtaaac
    15601 ttttcaacaa aatcacctgg acgacagatt gcctcggttg ttccatctaa ttgcttctta
    15661 ttgtcatcaa caaagacaat gaaatgactt agctgctggt gtgccgcaag ctggatagcc
    15721 tcccagcatt ggccctcgtt taattcccca tcaccaacga ttgcataggt ataatgtggt
    15781 gactgctcaa gcgcttgagc ataggcaatg cccgttgcta cgctaattcc ctgaccaaga
    15841 gagcctgtcg tcatgtcaat accaggcgtt aacagacgat ctgggtgcga gggcagactt
    15901 gttccattgg tattaagaga ctgtaaaaag gccttatcaa aaaacccctt taagtagaga
    15961 gtgctataga gggcaggacc cgcatgtccc tttgataaca ccagataatc tctatctgac
    16021 tggacaaaga gctctggtgt catgggcatg atttctccat aaagcacagc cagcaattct
    16081 acaatagaca agctaccgcc ataatgacca aagccaagat gattaagagt ctccaaggta
    16141 tttagacgaa tctctgctgc gaatcgcttc acatctgtta gaggctcatc actcaaaacc
    16201 atgcttattc ctccttagct actgattttc caacaacaga aagcccaaca agtccagcta
    16261 atatcacaaa aataccaatc acaatagctg tcacaccacc tatgctgtta agtgttccta
    16321 gtaaaatacc tgataagcca aaatcggcat ctgagaaggt tgagccctca aagcccaagc
    16381 cgcctaaaac aggcatcaag aaaatcggaa gatagctaat aagaacaccc tgtaaaaagg
    16441 ctcccacagt tgcaccgcgc acacctccag aagcattccc aataacacca gctgtggcac
    16501 cacagaagaa atgaggcaca acgccaggta aaatcactgt cgttccactt acgatcatca
    16561 cagccatgct cacaaggcca ccaacaaagc tagaaacaaa gccaatcagc actgcattgg
    16621 gggcataagg ataggcaatc gggcaatcca aggccggctt agaatgtggc actaattttt
    16681 cagaaatgcc cttgaaggct ggaacaattt cacccagaat caaacgaaca ccagctaaaa
    16741 tcacaaagac gcctgcagca aactgtcctg ccaactgcaa ggcaaagacc aagccatgtg
    16801 tgccagagga taattcctta ctaatccaag taggaccagc aaaaatagct acaatcaaat
    16861 aaatgattgc cattgataag gtaatgctta ctgtactatc acgcaaaaaa gcaaggctct
    16921 ttggaaaatc aatgtcctct gttgacttgg ttttgtctcc aacaagacct cctacaaaac
    16981 cgcttaacca ataaccaaga gagctaaaat gccccaaagc gaccttatcg ttaccagtca
    17041 gctggatcat ataccgttgc acaagagccg gtgaaacact catgataatc cctaaggcca
    17101 gcccaccaaa cacaatcaag gacactgacg tcaagcctgc aacagacata atcacagcaa
    17161 tcatacaggc catgtaaagt gtgtgatgcc ctgtcaagaa gatatactta aatcgggtaa
    17221 agcgagcaat caaaatatta aagatcattc ctgtaaacat aatcagagct gtcgctgacc
    17281 cataggtcgt caaagcaact gcaacaatag cctcattatt tggcacaaca ccagacagat
    17341 gaaaggcatg ctcaaacatc gttccaaaag ggttgagtga gccttgcacg atacctgcac
    17401 cacctgaaac cactaaaaac ccaacaaagg tcttaatgcc tcccttaaca atgtcaggag
    17461 caggcttttt ttgaagtaag agaccaacaa tagcaatcaa ggcaaccaaa atagctggtg
    17521 tgctaacaat atcaagtaaa aatgtcatct tatcctcctt ctaaacaagc cccttttcct
    17581 ggcaaatagc ctttaccaga ctagtcaatt cgtccatatc aatgatacta tttaaaatcc
    17641 tcacatctcc cagatgctct gccgagtctg ccaaatcacg cccaacaatc cacacatctg
    17701 ccgctgtggg atccgcgcca ccaagatcat aatgctccac ctcaacaccg gttactccca
    17761 agtcctttaa tacggattcg atattcatct gaaccataaa gctagaccct aagcctgaac
    17821 cacaggctgt accaattctt aatgccattt tatgcctcct ctgcaataat agttttaata
    17881 tcctcaaatg atttagacgc aagtaaagcc ttgacctgct cattgtctct taaaatggtc
    17941 gtcagccgag acagggcctt tagatgtgtt tcattatcaa tagcagcaat acaaattaac
    18001 aaacgaatct cctgcttagg atcatctaac aaataaatcg ggtgctctaa aacaagcatc
    18061 gacataccta cctgattcac accatcctct ggcctcgcat gtgggatagc aatcccctta
    18121 cctagattaa taaaagtacc aaactcctca accttagcaa tcatagcctc cgggtagctc
    18181 gcttgaatct gcccactctc taacaagggc tgagccgcca aataaatagc ctctctccac
    18241 cccaattgct ctgaggttga ttgataggtt ttcttggtaa ttaagtcttg taacactggt
    18301 cgaatatcct ttcttttcac accttgtctt aaatattgct gcaaagcaaa gcgcagcttt
    18361 tctttttgat gaatgaccgc atatgagctg ataagatgga gcagctcttc aacctctagc
    18421 cgatagccaa tatctggaaa atcacgatta accaagctga ccagctgaaa agcctgctca
    18481 tcagtcatta tcatagggac taaataaaag ggcttatcag tctctaatcg tatcgttgaa
    18541 aaaaccaaat catagccgct cttatctaat tgcccaagct gatcaagcct tgaaagcccc
    18601 cgaaaagcaa tatcaggaaa taaaagcttt aaatgctcct tgatcattaa agaagaacta
    18661 acaccattag gacagacaat cacagcctga taggcttgac gatgaaaatc tcttccctgc
    18721 tgctttaaat agcctccaaa atgaagaaca aaataagcaa tttcactatc tggtatagga
    18781 ctacccagct ccttggctaa aggctccaga gactgcttta ccaagtcaaa aagctcagaa
    18841 taactatcct taatccgcaa ggtataatca ttatcacttg gcaaaccata gcgcaaacgg
    18901 taataggctg gaatcaaatg ccttttcaaa ttctccttga gctgatctgc ctgactaaag
    18961 cttagtaaag caaccccctg catttgatca acaatcgcaa cggttagtga ttcaaagaaa
    19021 tcatcaccaa cagtaccctc accctcaaag cagcccgcta acagcaattg aaaataggcc
    19081 tcatcagctt caaatagctg atacttaaga gacaattgct gcattatttc tgccaccaaa
    19141 agggccgtta gctgatccag ctgctcagaa accactacct gtctttgctt gaccctatca
    19201 acccgtcttt ggtaacgaca taaaataaag atgacagcgt acaaacagac ctgcagacga
    19261 tcaaggatcg gagacatctg aaaggtctga taaaaatggc tcacacgttt ttcaagcgct
    19321 tcaaacgaca cctgatagtg ccaagaagcc aaaatatagt ccaaggccca caagccaata
    19381 ggagatttaa gcaaagtagc aatcattact aaagccaacc ggtgcttatt aatctcatca
    19441 ccaactaaga tatagccgct tgctctggta tactttaatt ccaagtcaac atctgccagc
    19501 ttctgccgca aggccttaat atctgtcaag gctgtgttct tgctgacctt taaaaagtcc
    19561 tgataatgac tatttgaaac aaaatccctg cggcaaaagg tatacagata gataagattg
    19621 atccgctctg cctgagaaag ataaacctgc tcagcattaa tcaacgtaaa caaatgatct
    19681 gactcagcct taagctgctg actgatccga tagccagacc ttgttgcatc tagctctgag
    19741 agctcatgct gagccaaaaa ctcattcagc tcatcaatac ggtccttaat ctctctaatg
    19801 gtgaattttg tcttaacact cagctcgtaa agtgataagt cttgataagt catcaacgtc
    19861 atcaaaatga caactgcttt gctatcaacc atttgatttc ctttctaaat tcattctatc
    19921 gaaaacggtt acaataaact agtccccatt gggcacaatt tcttatccaa catcatcaac
    19981 agcccttggg ctcaagatgc caatctaaac aggctaccag ctcctcctaa ctatcaataa
    20041 agagcaaaca agcccatctc tgccgctaag caattgtccc catgatttcc taagtccaag
    20101 ccaaagctaa agctctttgg agtaataacc gtcaaaaatg ttccaaataa tcaaaaaaac
    20161 tgattgacct catcagcatg tgataactct agatataagc ctaaaacaag attacagact
    20221 taatagttaa ctggtaatct tttattatac cacgaaaacg gttaccaaaa aagacttgtg
    20281 ttttattatt ttaataatat aatgaaacta taagatatct tattaaatga caaataacta
    20341 ccatcttggt tagaaaggag taaagctaat taacccttag tagatcacca tcgttttcag
    20401 aaaggaaatt caaaatgaaa aaagtaaaac aattgatcat cgcaatgata gcgtccttat
    20461 tactcattgc taacactgta ccttccattg tatatgctag tgaagtgact aaaattcaac
    20521 aggaagaaaa agtaattgaa gaaaaattat cacaacctct agaaatttca aaaagtgagt
    20581 tagatacatt aatccaagag aaaaaagctc tttatccaaa tttaacagaa caagaaatgc
    20641 gtgaaattgc gtataaagcc atgagtccat acacttttag agctagtgta tgggacgggc
    20701 aaggagtaac cttagatgaa ttcgcttggg cttttgatgt tattgtaggc gggttaatta
    20761 gtggatatgc aaccatcgga aagtacgttg ccaaacatgg agtagctgcc gctcgagctg
    20821 tacttagccg agctgcaaaa gctgcagctc aacgacttgg tgtactaacc ggatttattt
    20881 ccggtttact tagagctgca ttctcagtaa taaacattta ctataatgtc ggatatgccc
    20941 tagcacaata tgtcgatgct cgagattatc acccaaataa cggtcgtata aatgcgtggg
    21001 cttaagaact atatttgtta ttttattatt gtaatgtcag tttatacagc aatagcatat
    21061 tgtttcaatc gcttatcctt atcatttact ccaaaactag ttttctattc ggccataacc
    21121 acctatactt tttacataac aaaaaataaa gactga
//
LOCUS       DARYLD010000036        20475 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYLD010000036 DARYLD010000000
VERSION     DARYLD010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20475
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(279..627)
                     /gene="ssrA"
                     /locus_tag="TU651_001241"
     tmRNA           complement(279..627)
                     /gene="ssrA"
                     /locus_tag="TU651_001241"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            718..1329
                     /locus_tag="TU651_001242"
     CDS             718..1329
                     /locus_tag="TU651_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL0897245.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            complement(1376..2170)
                     /locus_tag="TU651_001243"
     CDS             complement(1376..2170)
                     /locus_tag="TU651_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897246.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(2180..2878)
                     /locus_tag="TU651_001244"
     CDS             complement(2180..2878)
                     /locus_tag="TU651_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897247.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            complement(2878..3249)
                     /locus_tag="TU651_001245"
     CDS             complement(2878..3249)
                     /locus_tag="TU651_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0897248.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            3491..6601
                     /locus_tag="TU651_001246"
     CDS             3491..6601
                     /locus_tag="TU651_001246"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL0897249.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            6681..7694
                     /gene="pfkA"
                     /locus_tag="TU651_001247"
     CDS             6681..7694
                     /gene="pfkA"
                     /locus_tag="TU651_001247"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL0897250.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            7756..9258
                     /gene="pyk"
                     /locus_tag="TU651_001248"
     CDS             7756..9258
                     /gene="pyk"
                     /locus_tag="TU651_001248"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL0897251.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            9387..9944
                     /gene="lepB"
                     /locus_tag="TU651_001249"
     CDS             9387..9944
                     /gene="lepB"
                     /locus_tag="TU651_001249"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL0897252.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            10121..11932
                     /gene="glmS"
                     /locus_tag="TU651_001250"
     CDS             10121..11932
                     /gene="glmS"
                     /locus_tag="TU651_001250"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL0897253.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            12116..12451
                     /locus_tag="TU651_001251"
     CDS             12116..12451
                     /locus_tag="TU651_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL0897254.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            12558..13199
                     /locus_tag="TU651_001252"
     CDS             12558..13199
                     /locus_tag="TU651_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0897255.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            13209..13838
                     /locus_tag="TU651_001253"
     CDS             13209..13838
                     /locus_tag="TU651_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL0897256.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            13855..14691
                     /locus_tag="TU651_001254"
     CDS             13855..14691
                     /locus_tag="TU651_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0897257.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(14787..16025)
                     /locus_tag="TU651_001255"
     CDS             complement(14787..16025)
                     /locus_tag="TU651_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL0897258.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(16128..17462)
                     /locus_tag="TU651_001256"
     CDS             complement(16128..17462)
                     /locus_tag="TU651_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL0897259.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(17591..17677)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            17942..20233
                     /gene="pcrA"
                     /locus_tag="TU651_001257"
     CDS             17942..20233
                     /gene="pcrA"
                     /locus_tag="TU651_001257"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL0897260.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT         5999 a         3763 c         4682 g         6031 t
ORIGIN      
        1 taaagcagca gtaaatgatg tctatataac aggcaataca gggcaattat ccgaaaaaat
       61 ttgataatgt gctgtcaatg aagcaagtag aagaagtatt ataaaaaaat aaatataaga
      121 ttagctaaag agaaaattca agctgttctt aaaggatttt ttggcctttt ttttgctatc
      181 actttcatag aaacttacgg taacccacga acaggacaaa aagaaaaaac cttgatttaa
      241 caaggtttta gtaagctatg gtaacttacg gtaagtattg atggagctgg tgggagtcga
      301 acccacgtcc aaacacctgc taacctattt gtctacaacc ataggttatg tcttacttta
      361 acagaccaag gacacataac tcaagccatc agcctgcgag tctagggttc tctttttagg
      421 tgactagaca atcacctaaa cgtagcttgc tgttttgaga cctctaataa gacacaagca
      481 atcctataga agtcacgccg gctggttttt aggcagctaa agcgtaagtt gtgttatttt
      541 ttgcagttat atttaactgg catttttaca tctgccgatg agttgcaaaa taggcctcat
      601 aatgcctgtc gaatccgtaa caaccccata aaaaggcgta tgagatactt acggatgcta
      661 gtatagcaaa atttttttaa aatggcaaaa aaatagcgct tatggtatga tgaagctatg
      721 agaaataatg agttgaagcc ttatgtgata tggcaaaaag tgattaagct attaggaagt
      781 ctggctttag tcggatcttt tttgctagcc ttttggtttt acaggcttgg cattttaaat
      841 gacagcaatg cactcaagga tcttgttcat agtcacaagg tttttggccc ccttgttttt
      901 gtcggtgtgc aaattgttca gattgttttt cctattattc caggtggtat gacaactatt
      961 gcaggctttt tgatttttgg ccctttgctg ggttttcttt ataactatgt tggtatcttc
     1021 attggtagtg tgattctgtt tttacttgtg aagacctatg gtaggcgctt tattttactg
     1081 tttatagagg aacagacctt ttacaagtat gagagaaaat tagagatgcc atattatgag
     1141 agattgttta ttctctgtat gctttctccg atttcaccag cagatattat ggtcatgatt
     1201 actgggctga cagagatgtc gttgaagcgt tttgtgacca ttattttaat cacgaagcca
     1261 ctatcaatta ttggctacag ctatcttttt atctttggaa aggatttgat cctatggttt
     1321 ttccattaaa aaagtctagg cattgcctga taagcagtgg ctagactttt tgttatcatt
     1381 ggatattaag cttgtttttg atgatgaagt gagtagcaac gtaaaggata atgccttcaa
     1441 ctagttgctc tatgtttaaa atagatatgg ctgtatgatc accgaaatag agtagcgagt
     1501 ctgagctatt tgggttgacg gtgaaaaacg catcatttaa ataagtcatg acgacaataa
     1561 tgataataac taaaatgaaa taggcacaaa atgccatcaa accacgacga tttgaaaata
     1621 gctgaccaat tgagattgct agataaatca atagtatact tgttatggtt gacaaaagca
     1681 tgtagatgag gatagaagca ttttcgacta agttttctgg cttcataatt gtctttagca
     1741 cctttagtag ataggtaaag tcaactgttg gcgctattaa aataaagata ccgattaata
     1801 ggttaatgcc attaaaaata ctgcaaacaa aggacgctaa cagcttggac aagataatct
     1861 gatgtgctgt tactggtagt gtcagtgtta agtatccctc gcgcccaaag acatttttgt
     1921 taaagcgatt aatgatgatt aatagcgttg ataagaatga tccggcaatc agagaaccaa
     1981 acgttaatga gagtgtgaga ggaaccattt tgtttgccag acttgttgtt aaaccaacct
     2041 cgtcaggatt gtttgtaagc gtattgatgg taaaagaaag gactatcgcg atagcaatga
     2101 caccggcatt aagcgcaaaa taccacttgc caattgatct aaattcgtat tttaataatt
     2161 ttccaaacat gcctacctcc taaaccttgt agatctctct aaataatgaa tcaatcgatt
     2221 gctgatgctg aactcgtaaa tcatcagcgt ttccagaaag gcagagctta ccatttttta
     2281 agaaaatagc ttcatcaagt acaggctcaa tgtctgagat gaggtgagta gaaatgataa
     2341 cagaggcttg ctcagagtaa ttattaataa tggttttaag aatataatct cttgctgccg
     2401 ggtcaacccc tccgataggc tcatcaagga tatagagctt tgctttgcgg ctcatcacga
     2461 ggataagctg tgccttttcc ttatttccct ttgataggtt tttaaagcgc tcttcagcat
     2521 ctaagtctaa atccttcagg agactggtcg ctttatctct gtcaaaatcg gcatagaaat
     2581 caccaaaaaa gtctagcata tccttgattt tcatactttc attaagatag gtcgtatctg
     2641 gtaagtaaga aatgattttt ttagtttcta cagatggtct aaagccgtca ataacaatgt
     2701 ctcccttgtc tggctgtaaa agtccgttga ttagcttaat tagtgtagtt ttgccgctac
     2761 catttggtcc tagtaagccg ataatttttc cagaagggat tgttatggtt aaatcatcaa
     2821 tagctaattg ttttttgtaa gattttgaga cgtggtgcag ctgtaatagt tgtgccatta
     2881 gtttgatccc tcctctaaaa aggtacttaa aacaggaatg atttctgaac gttcaaaacc
     2941 tattttgatc atattgctaa taaaggactt gagctcgttg atggccagct ctcgtctttt
     3001 gcgcgcgata agctcttggt tatctgttac aaaccggccg gcagttcgtt gcgagtaaac
     3061 tatgccttca cgatctaatt cggtaagtgc tctttgcatg gtgttgggat taacgccggc
     3121 aatttcagca tattctcgga cagtcggcag ctgatctcca cttttgatct cttggctgac
     3181 aatttgcagc atgatatgct gtgctatctg tgcgtaaata ggagatttct catcaaattt
     3241 ccaagacata ctgtctcctt tctttctaaa atctgcgatt aatatttgta ctaattaaat
     3301 gatacaaaaa aacgattgac ttgtcaagcc ttgtgtgtca tctctagtta catactggct
     3361 tgcaatgcta gtgggattcc tgctgatagt ggtgcagtaa agacagatca ctgctattaa
     3421 aagcttaaaa tctgggcagt aaagtctttt tcatagtata atggtagtaa gaacgctaaa
     3481 ggagatgtcc atgtttgctc agttagatac aaaaacagtt tattccttta tggatagttt
     3541 gattgattta gaccattatt ttaaacaagc caaacgatta ggctatcaag ccatagggat
     3601 tatggatcag gataatctat atggggcata tcattttatt aagggctgtc aaaggcatgg
     3661 gcttcagccg attttaggtc ttgaggtggc tattacagtt aaagagcagg ctcttacgct
     3721 gaagcttgtt gcgaaaaatg atacaggcta tcagcagctc ttaaagcttt cgactgaaaa
     3781 aatgtctgga gacctagacc tagacacatt ggtgcagtat ttagaaggga tagcagttat
     3841 cgttcctttt agtcagagct tgcgtgattt agggcttcct tttgattact tcattggcat
     3901 tgatgaggca agcgacttgt caaagataga ctctacagaa agactgattc cgcttagaac
     3961 ggtacgttat tttgataatg ctgagactga gactctgcaa atgctgcatg ccattcgtga
     4021 taatattagc ttagcagata cggctctagt agccaaggat cagtttttag cgccttgtca
     4081 ggagatgacg gctattttcc aggaaaagtg ccctgaggct ttggtgaatc tcgtaaatct
     4141 aacagcttcg attgcttatc attttgatac tgatttaaag cttccgagat ttaaccgcga
     4201 taagccagca aaagaagagc taagagaatt gaccgagtct ggtctaagag aaaagcaatt
     4261 atggaaggag ccttaccaat ttcgtctggc agaggagctg gctattattt cagatatggg
     4321 gtttgatgat tattttctca ttgtctggga tttgctgcgc tttggaagga gtagaggcta
     4381 ttatatgggc atggggcgtg gttcagcagc aggcagtcta gtggcttatt cgttgcgcat
     4441 tactgggatt gatcctgtca aaaacaattt attgtttgaa cgctttttga ataaagaacg
     4501 ctacagcatg cctgatattg atattgattt gcctgatatt taccgctcag agtttcttca
     4561 ttatgttcga gaccggtatg gtagtgagca ctcagctcag attgttacct tttcgacttt
     4621 tggtcctaag caggctgttc gtgatgtgtt caaacgcttt ggtgtcccag aatacgagct
     4681 aacaagccta actaaaaaaa ttgggttcaa ggataccctg agcactgttt atgagaaaaa
     4741 tatagccttc agacagacca ttaatagccg cttagagttt caaaaggcat ttgagatagc
     4801 taagcgcatt gaaggcaatc caagacagac ctctattcac gctgctggta tcgtgatgag
     4861 tgatgaccat ctgaccaacc atattccctt aaaaaagggg gaggatatga tggtgactca
     4921 gtatgatgcc agtgctgttg aagctaatgg cttgctgaaa atggattttc ttggtctgag
     4981 aaatttgacg cttgtacaga aaatgcagga aaaggtggtc aacgattacg gtctttcaat
     5041 tgacattgaa gctattaacc tagaggatcc tgaaacgata gccttgtttg ctaggggtga
     5101 taccaagggc atttttcaat ttgaacagca tggtgcgatt agcctgttaa aacggatcaa
     5161 gccgactagc tttgaggaaa ttgttgcgac aaccagctta aatagaccgg gagcaagtga
     5221 ttacacgcag aattttatta agcgccggca gggacaggaa aacattgatc taatagatcc
     5281 ggtgattgct ccgatattag agccaaccta tggtatcatg ctttatcagg agcaggttat
     5341 gcagattgct caagtttatg caggctttac acttggaaag gccgatttgc tacggcgtgc
     5401 tatgtctaag aaaaacctcg ttgagatgca aagaatgcag gaggattttc tgactggtgc
     5461 tagagccttg ggtcgctctg aggagacagc cagactattg tttgcacgta tggaaaaatt
     5521 tgcaggctac ggctttaacc gcagccatgc ctttgcttat gctgccctag cctttcagct
     5581 agcctatttt aaagcgcact atcctgaggt attttttgat gtcatgatga attattctag
     5641 cagtgattac atcacagatg cgttagattt tggctttgag gccgcgcagg tgacgataaa
     5701 caccattccc ttcaatgata agattgagcg tcataagatt tatatgggct taaaaaacat
     5761 caagggtctt cctagagaat tttcgtattg gatcattgaa aataggccct ttaccagtgt
     5821 tgaaagcttt ttgtgcagca ttcctgaaaa ataccagaaa accagcttct tagagcccct
     5881 tatcaaaata ggcctgtttg atgggtttga aaaaaatcgc caaaaaatca ttaacaactt
     5941 agaaggactg ctaacctttg tcaatgaatt gggatcactt tttgcggatt cctcctttag
     6001 ctgggtagag actgaggatt attcagctgc tgagaaatat tactttgagc aggatttgct
     6061 tggtgttggc atgagcaagc accccttgct agctgtcgct gaaaaaagca cagtagcagt
     6121 cacaccaatc acaaagttag tgaaggatac agaagctact ttgctggttc aaatagatgc
     6181 gatcagggtt attcggacaa aatcaagcgg acagcagatg gcctttttga gtgttactga
     6241 taccaaacag aaattagatg ttaccctttt tcctgagcaa tatgctgtct ataagcaaga
     6301 cctaaaagag gggcatattt actatatcaa tggcagggta aaagaaagag ataaccgctt
     6361 gcagctagtc tgtcaccagc ttcgattagc tcagagtcaa aggtattggc tattggttga
     6421 aaaccatcag catgatgctg ctatttctga catattaaca gccttttcag gggagactcc
     6481 tgttattatc cattatcaag aaggcaaaga aaccttagag ttaaaccata ttagggttga
     6541 tgttagtaag gatttggagg aggctattag cccctacgtg ttgaaaacgg tttttcgata
     6601 aaaatagcga attagtgaag taatttgcaa acgaatgtgc tataataaaa acgttaaatt
     6661 aattaaagga gtaccaaaaa atgaaacgta ttgctgtttt aaccagtggt ggtgacgccc
     6721 ctggtatgaa tgctgctatt cgtgcagttg ttcgtaaagc aatttcagaa ggaatggaag
     6781 tctatggtat taaccgcggc tatgctggta tggttgatgg tgatatcttt ccactaggct
     6841 caaaagaggt tggtgataag atttctcgcg gcgggacctt cctttattca gctcgctacc
     6901 cagagtttgc tcagcttgag gggcaattgg ctggtattga gcagctaaaa aagcatggca
     6961 ttgaaggggt agttgtcatt ggtggtgatg gttcttacca tggtgcgatg cgcttgactg
     7021 agcatggctt ccctgcagta ggtatcccag ggacgattga taacgatatt gctggaacag
     7081 actatactat cggatttgac actgcggtca atactgcggt agaggctatt gataagcttc
     7141 gcgatacctc atcaagtcat ggacggacct ttgttgttga agtgatggga cgcaatgcag
     7201 gtgatatcgc actttgggca ggtattgcaa gtggagcaga tcaaatcatc gttcctgaag
     7261 aggaatttga cattcataaa gtggtctcaa caattaaaga cgattttgaa aatagaggaa
     7321 aaaatcacca tattatcgtt ttagctgagg gtgttatgag tggcgaggcc tttgcgcagc
     7381 agctaaaaga agctggagat gaaagtgacc ttcgtgtgac aaaccttggt catatccttc
     7441 gcggtggctc tccaactgcg cgtgatcgtg tgattgcgtc atggatggga gcgcacgctg
     7501 ttgagttgct caaggaaggc aaaggtggct tggctgttgg tattcataat gaagagcttg
     7561 ttgaaagtcc gattcttgga agtgcagagg acggtgcctt gttcagcctt actgatgagg
     7621 gtaacattgt tgttaataac ccgcacaagg ctcgcttaga ctatgctgct ttgaaccgtt
     7681 cattagcaca ataggataag taagatctgg taatctttgt taatcaacta aaaaataagg
     7741 gagtttcata ataaaatgaa taaacgtgta aaaattgttg caacacttgg tcctgcggtt
     7801 gaaattcgcg gtggtaaaaa atatggtgag gacggctatt gggctggtca gttggacgtt
     7861 gaacaatcag ctaaaaagat cgctgaattg attgaagcag gtgctaatgt tttccgcttt
     7921 aacttctcac atggtgacca caaagagcag ggtgaccgta tggctactgt tcgtcttgct
     7981 gaaaagctgg cacgtcaaaa ggttggtttc cttttggata caaaaggacc agaaatgcgt
     8041 acagaattgt ttgctgacga tgccaaagaa tatagctatg tgactggtga gcgtattcgt
     8101 gttgcgacag cacaaggcat tcaatcaact cgtgatatga ttgccttgaa tgtagctggt
     8161 gctcttgata tttatgatga ggttgaggtt ggccacacta ttcttattga cgatggaaag
     8221 cttggcttaa aggttatcga gaaggacatt gcaaagcgtg agttcatcgt tgaggttgaa
     8281 aatgatggca tcattgcaaa gcaaaagggt gttaatatcc ctaataccaa gattcctttc
     8341 ccagccttag cagaacgtga taatgctgat attcgttttg gtcttgagca aggtcttaac
     8401 tttattgcta tttcatttgt tcgtactgcc aaggacgttg aagaggttcg tgagatttgt
     8461 cgtgaaacag gcaatgagca tgttcaatta tttgctaaaa tcgaaaacca acaaggtatt
     8521 gataaccttg atgaaatcat cgaagctgca gatggtatca tgattgctcg tggtgatatg
     8581 gggattgagg tgccatttga aatggttcca gtcttccaaa aaatgattat caccaaggta
     8641 aatgcagcag gtaaagcagt catcaccgca actaacatgc ttgaaacaat gactgaaaaa
     8701 ccacgtgcaa ctcgttcaga ggtatctgac gttttcaacg cggttattga cggtacagat
     8761 gcgacaatgc tttctggtga atcagcaaat ggtaaatacc ctgttgaagc agttcgtaca
     8821 atggctacaa ttgataaaaa tgcacaaact cttcttaatg agtatggtcg tttagattca
     8881 tctgccttcc cacgtaccaa taaaactgac gtgattgctt cagctgttaa agatgcaaca
     8941 cactcaatgg atatcaagct tgttgtgacc atcactgaaa caggaaacac agctcgtgcc
     9001 atttctaagt tccgtcctga tgctgacatc ttggctgtga cctttgatga aaaggttcaa
     9061 cgtgccttga tgattaactg gggtgtgatt ccagtgcttg ctgaaagacc agcatcaaca
     9121 gatgatatgt ttgaggtagc agagcgtgta gctcttgaga ctggtttggt gcaatcagga
     9181 gataatatcg ttattgttgc aggtgtgcca gttggtacag gtggtacaaa tacaatgcgt
     9241 gttcgcactg taaaataata gctttccata agctttagct attttgctct atcagataat
     9301 ttaaggcaaa caatgatact taaaaattgt ttgctttttt tattagtcat atcatgttat
     9361 aatgagacta tagactagga gttattatgg taaagcgaga ttttataaga aatatattgt
     9421 tgttattgat tcttattgtg ggagctgtcc ttcttagaat atttgttttt tcgacctatc
     9481 gagtcacgtc agaggcttca aatgcctatt tgaataaggg cgatttaatc accattaaga
     9541 aaaatattga gcctaaatat aaggattttg tggtttatac ggttgacaaa aaggattatg
     9601 tgagccgggt tgtagcagta gcaggtgatc gtgttaccta tatggacgat attttttacc
     9661 tgaacaatat ggttgaatcc caatcctacc ttgagagtat gaaggcaaag tatctcaatc
     9721 atgcccctat tggtacgctt tatacggagg attttacgat ttcgacggtt acttctggaa
     9781 aatacgatag cattcccaag gggaaatacc ttttgctaaa tgataacaga aaaaaccatc
     9841 atgatagccg tcagtttggc ttaattgacg tgtcacaaat taagggatta gtaacattta
     9901 gagtgcttcc tttgaaagac tttggatttg tagaggtaga gtagctttaa ggctgctcta
     9961 ttttgtttct caaaatatga ctataccaat tttcttgttg acaagatttt tctgaagtta
    10021 tatactctaa atataacgtt ttagtcggtt tatatctgac tataccaatt atattgatca
    10081 ttaaagaaag tagtaagcta gcttactgag gtgttaagtt atgtgtggaa ttgttggagt
    10141 tgtaggtagt cgtaatgcga ctgacatctt gatgcaggga ttggaaaaat tagagtatcg
    10201 tggttatgat tcagctggta tttttgtgtc agatggcagg acgtccaatt tggtaaaatc
    10261 tgttggacgc attgcagatt tacgctctaa gattggcatt gatgttgttg gaacgaccgg
    10321 tattggtcat acacgttggg caacgcatgg tcaagcaaca gaggaaaatg ctcaccctca
    10381 tacctctcag acaggtcgct ttgttcttgt tcataatggt gtgattgaaa attacctcca
    10441 gatgaaggag cagtaccttg ctggacacac gtttaaagga caaacagaca ccgaaattgc
    10501 agttcatttg attggagcat ttgttgaaga aggctgttca gtcttagagg cttttaaaaa
    10561 ggctttatca atcattgaag gctcctatgc ctttgctttg attgatacag aggatatgga
    10621 tacgatctat gtcgctaaga ataaatcccc attgctgatt ggccttggtg agggctataa
    10681 catggtttgt tcagacgcta tggccatgat tcgtgaaacc agcgaattta tggaaatcca
    10741 tgacaaggag ctggttatcc tgacaaagga ttcagcaagg gtgacagatt atgctggcaa
    10801 tccgattgat cgtcagtcat atacagcaga gcttgatctt tcagatattg gcaaggggac
    10861 ctatccattt tatatgctaa aggaaattga cgagcagcca acagtgatgc gtcgcttgat
    10921 ttcaacctat gcagacgcca agggacagat gatgattgat ccagctatca taaggtctgt
    10981 ccaagaggct gatcgtatct atattcttgc agctgggacc tcttatcatg ctggctttgc
    11041 ttctaagtca atgctggagc atttgactga tacacctgtt gaattagggg ttgcttctga
    11101 gtggggctac aatatgccgc tattgagcaa aaagccaatg tttatcctct tgagccagtc
    11161 cggtgagaca gcagatagcc gtcaggtttt ggtcaaggca aatgagatgg ggattccaag
    11221 cctaacagtg acaaatgttc ctggctcaac cctatcacgt gaagcaacct acactatgct
    11281 gctccatgca ggtccagaaa ttgcagttgc atcaactaaa gcctacacag cacaggtcgc
    11341 tgcacttgcc tttctagcta aggcagttgg tgaggctaat ggcaagaagg aagctattag
    11401 ctttgatttg gttcatgaat tgtcattggt cgctcagtct attgaggcca ccttatctga
    11461 caaggagctg attgctgaga aggtgcagac cttattggca acaacacgca atgcgtttta
    11521 cattggtcgt ggcaatgatt attatgttgc tatggaggct gcactaaaat taaaagaaat
    11581 ttcatacatt cagtgtgaag ggtttgcagc tggtgagcta aagcatggga ctatttcact
    11641 gattgaggat ggcacacctg ttattggact tatttcttca agtgagctgg ttgctgcaca
    11701 tacacgtggc aatatccaag aggtggctgc acgtggcgct catgtgttga cagttgttga
    11761 ggagggctta gagcgtgagg gagatgacat tattattaat aaggtgcacc cattcttagc
    11821 gccgattgct atggttattc cgactcaatt aattgcttac tatgcttcct tgcagcgtgg
    11881 tttagatgta gataagcctc gtaatttagc caaggctgtt acagttgagt aatagttgcc
    11941 tgcttaaaat gaggcagcag ggtcctgaag cctatttgaa acgagcttga catgatgtta
    12001 tgtcaggctc gttttttagt gcttgcctgg tcttatgata acgtattcat cttgtcaaat
    12061 aagcatttct gaagtaaaat attaacgtta agactaagaa gcttaggaga gtaagatgac
    12121 gttaccaaat tgtttacaat gcgattcaga atatgtttat gaggacgggc atttgctcat
    12181 ttgtccgatg tgttcctttg aatggacacg tggtgaggag gagcctgagg aggaggggct
    12241 tgtcgtttta gatagtaatg gaactagatt agctgatgga gacactgtta cgatcattaa
    12301 ggacctgaag gtcaagggag cgccgaagga tctcaagcag ggaactcgtg ttaagcatat
    12361 tcgtcttgtt gaaggtgatc acaatattga ttgtaagatt gatggctttg gtgcaatgaa
    12421 gctaaaatca gaattcgtca agaagattta ataacaataa gcaaccagat gactggttgt
    12481 atttttatag aaaagtactt ttcaatccat cagaaaattt ggtataatgg ataaactatt
    12541 tatatctagg agacaacatg acgtatatta tgcaggtttt acccagcttg ctggatggtg
    12601 ccttaatcac tttacaggtt ttctttattg taattgtatt atccattccc ttaggggctc
    12661 ttttagcttt tttgatgagg gttgacttta agcccttgca gtggctattg acgctctata
    12721 tttgggtcat gaggggaaca cccttattgt tacagctcat ctttttttat tatgttttgc
    12781 caagtgtggg tgttaccttt gatcgtatgc cggcagcgat tttggctttt accttaaact
    12841 atgctgctta ttttgccgag atttttcgtg gcgggataga gactattcca aatgggcaat
    12901 atgaggctgc aaaggtgctg aagcttagtc cggtacaaac tgttcgctat gttatcttgc
    12961 ctcaggtgtt caagattgtt ttaccaagtg ttttcaatga ggtgattaac ttagttaagg
    13021 attcttcctt ggtatatgtg ttaggagtag gggatttgct attagcaagc aagactgcgg
    13081 caaatagaga tgcaacctta gcaccgatgt ttattgcagg tttgatttat ttgctcttaa
    13141 ttggtttggt caccatttta tcgaagcagg ttgaaaaaag atttaattat tatcagtaag
    13201 ggggtcatat gttagaactg aacaatattt caaagcgatt tggtcacaag cagatctttg
    13261 atggctttca tttgaccgtt gaagatggtg aggttttatc tttggtaggg ccatctggtg
    13321 gtggcaagac tactctgctc cgaatgctgg ctggcttaga gcctattgat tcgggaaata
    13381 ttagctataa tggcgagtct gttcctattg atcatttaga aaaaagaagc ctgcttggtt
    13441 ttgtttttca ggatttccaa ttgtttccac atttgacggt gctggataat ctcatcttgt
    13501 ctcctaccat taccatggct atgccaaggc ctgatgcaaa gcaaaaggct atggagctgc
    13561 tggagcgcct aggtctcaaa gagcatgcag ctgcttatcc ttatgcgcta tctggtgggc
    13621 aaaagcaaag agttgccttg gctagagcga tgatgattga cccacagatt gtaggctatg
    13681 atgagccgac aagtgcctta gactctgaat tacgtcagga ggttgagaaa ttgattttgc
    13741 aaaatcgtga gatgggcatt acccagattg ttgtcaccca tgatttgcag tttgctcaga
    13801 ccatttctga tcgtatcatc aagatcaatc ctaaatagaa gaagaggtag tgctatgacg
    13861 ttaaaaaaga cccttctagt agccctattt gctgctacag ctacgctttt agtagcttgt
    13921 ggcgctagta ataaacagac tagctcagat gcttgggatt cctacaagca gaaaaagacg
    13981 attacgcttg gctttgataa tacttttgtg ccaatgggct ataaggacga gtcaggaaaa
    14041 aataccggct ttgatattga gctagcaaag gctgtttttg accaatatgg tatcaatgtt
    14101 aagtatcaag ccattaactg ggatctcaaa gaaactgagt tgaacaatgg taaaattgac
    14161 ctgatttgga atggctattc tgtgacaaaa gagcgccaag ctaaggtggc ctttacagag
    14221 ccttatatga aaaatgagca agtcttagtg acgcaaaaat catcgcaaat aagctcattt
    14281 gctgatatga aaaataagac cttaggtgcc cagtctggct catctggcta tgatgccttt
    14341 acgagtcatc ctaaggtgct aaaggatctt gtcaagggaa atgacgctac ccaatatgaa
    14401 acctttacac aagcctttat cgatttaaaa aacaagcgta ttgatggcct tttgattgat
    14461 agggtttatg ccaattatta ccttcagcaa gaaggtgagc tagaccgcta taacattatc
    14521 gcgagtgagt ttgaaggtga ggattttgca gttggtgtcc gaaaagcgga taaaacccta
    14581 caaaaaaaga ttacacaagc cttaaaatcg ctttatcagg acggtacctt ccaaaaaatc
    14641 tctaaaaaat ggtttggtga agatgtcgca acagttcagt tgaaatcata agacgcaagc
    14701 aagacctaat cagctcagag gggttgagac tagatacatt taaaagactt accttctaaa
    14761 ggcaagtctt tttatacggc ttattattag ctgatacgct tgatatgata gtgtttttta
    14821 attgctatgg agtttgttat tggtgtgatt tgatgatata tcaggtgcca agcttcgtgt
    14881 cgtctccaga tactggtatg ctgattgccc tgtagctgat aggtgactag cttggtgttg
    14941 tggctgatgg attgcataca aaaggcttca agctgattgg aagaagaacg ctgctgctct
    15001 aaaaattgct tggcattgta agcttgtcca tcgcgatcaa taaaggtaaa ggtcttggca
    15061 atgagctctt gataatctgg gatttgactt agcatgattt tctcgttttt gtagagcttt
    15121 ttgtaaacat attcacagtt gtcatcttta ggaagctttg caggctcaac atgaatatca
    15181 atatcataaa cagcaaattg ctcactcaag agctgttcga cctgctcggt tatggcgtga
    15241 ctttcataaa cagaaaggtc agggtgcatc tcaaggacaa tatctaaata gacattgctt
    15301 ccgtaagtgc ggccgcgctg tgatttgaca gcaatgattt tgggaatttt caatatggcc
    15361 ttttcatatg ctttgagctg cgtgctgtca aagccatctg ataagctaaa ggcgcttgcc
    15421 ataaaaatat caaaggctgt ttttagaatg aaaaaggtaa tgataagggc agccagccta
    15481 tcaataatag gtagctttaa ggaagcggcg ataatagcaa tagaggttcc aatagaggtc
    15541 acagcatcag aaagattatc tttagaggct gcaaccaagg cactggatct tacctttttt
    15601 gataacgctt tattaaaagc atatactcca agcatcacaa gggctgaagc gatcccaaca
    15661 atagcaccta atggatcgat agcagactgc ttaccactaa tcatctgttg aatagtttgc
    15721 aggagaacct gaaagccaac aatgaacatg ataaaggagg ttattaagct tgaaaggtct
    15781 tcgattttcc agtggccaaa gcggtgattg gcgtctgctg gctggctggc cagatgaagt
    15841 ccgatgagca gagtgacatt accaacgata tcagacaggt tgttgaagcc atcggcaatc
    15901 aaggagctgg catttaaaag atagccagca agaagctttg tgatgctaag ggccaaatag
    15961 gtaacaatgc taacaatggg ccctcttttt gctaaccgaa ggttttctac tggattgttt
    16021 ggcataaaaa ctcctttgta actgatgctt tcattatatc ataaaagcta agacaagcta
    16081 aaagcctaga gctatcctaa atagggtatt ccaggctttt cgatagctta tttggtgctt
    16141 tggcgcttaa aatatgccct tgtctcaaaa atgacaacag gagataaggc tagtagggcg
    16201 ataagatttg gcagagccat caggccattg acaatatctg ccagtatcca aatcaactcc
    16261 agcttaagaa agccaccaag tcctaccatg ataacaaaga tcaggcgaaa atagctgagg
    16321 tgtgtcgtgc caaataaaaa gataaagcag cgctcaccat aatagctcca gccgagaata
    16381 gtcgtaaaag caaaaagaac aagcgacagg gtcaaggcat aggtgcccat atgcccaaag
    16441 atagaagcaa aggcagactg tgttaagggt gctccctcta gtgcgctagt ccactgacca
    16501 gttaccaaaa tggccagacc agtcagagtg cagatgatga tcgtgtcaat aaaggttccg
    16561 gtcatagaaa tcaggccctg ttctactggc tccttggttt tagcggcagc agcagcgatc
    16621 ggagcagagc ctagtcctga ttcgttagaa aaaaccccac gtgcaatacc cttttgaatg
    16681 gcgtccttaa ccaagcttcc ggcaaagccc cctatagctg ctgtaggggt aatagcggac
    16741 ttaaagataa ggacaagcat aggaagaagc ttagtatagt gaacagcaat aaccgttaag
    16801 cttgctccaa tataaaagat agccatgaaa ggaacgactg tttcagccac cttggcaata
    16861 gcttgaatgc ctccaaaaat aatcatggcc acaacagcag ctagcaagac actgattaat
    16921 ggcgaagaga tcccaaggct atggtgtagg gatgaggtaa tcgcattgac ctgagcaaat
    16981 gtcccgattc caaacaaagc cactaaaata ccagagacag caaataagtt ggctagaggc
    17041 ctccattttt gccccatacc atttaaaatg tagtacatag gtccgcctga aatctgacca
    17101 ttagcgtcct tagtacggta tttaatggct aaaacgccct cggaatattt ggttgccata
    17161 ccaaagaagg cagcaaccca catccaaaaa agtgccccag gtccaccaga ctttatagcg
    17221 gttgcgacac caacaatatt accagtacca actgtagcag ctagggctgt tgctagagca
    17281 gcaaatgatg aaatatctcc ttgcccctca ttcttagcaa aaatgagcct aaaggcctta
    17341 ggcaacttga tgacttggag aaggctaagt ctgctggtga ggtaaatgcc agtaccaagc
    17401 agcagtagca acaagggtgc tccccaaacc aaatcgtcta tccattttgc agcagctatc
    17461 atgcttaatt cctcaactct cttaaccaat gctgccaaaa gaaaaagcca cccctgcgga
    17521 tagcctctga agcatatgac aaaacagcaa gcacaaaaaa tgctaaggaa gcatgatcat
    17581 acggcttgat attttatctt ctgtcctttt gcctgagaga ttgagcagtc ttgccttgcc
    17641 ccttcggcgc ctaataggtc tctccagaag cccgtccgtc aagcagtccc gtccaacacc
    17701 tgaacacctg agagtataac tccttcggcg aaatccattc ttctcctgca tgacatcatt
    17761 cggtttatta aattatgtct atgataccca aaaagcctag tgatgtcaac aagcaattta
    17821 actgatggct aactccttgt ttttatggta acatcattgt cctctttttt ctttttgact
    17881 gaaacatgat ataatcgtaa ggttaataaa agtcacttat tagacgatat gaggagaaag
    17941 catgaatcct ttattagatg gaatgaatga taaacaagca gaggcagttc aaacgactga
    18001 gggccccttg ttaattatgg ctggtgccgg ttctgggaaa acgagggtat taacccaccg
    18061 cattgcctac ttgattgatg aaaagtatgt taatccctgg aatattttgg cgattacctt
    18121 tactaataag gctgcgcgtg agatgcgaga aagggcattg gccttaagcc cagccaccaa
    18181 ggataccttg attgcgacct ttcactcaat gtgtgttcgt attttacgcc gtgaggcaga
    18241 tcatattggc tacaatcgga atttcacgat tgttgatcca ggagaacagc ggaccttaat
    18301 gaagagaata gtaaaagctc taaatctgga tcctaagaaa tggagcgagc ggtcgatttt
    18361 agccaccatt tcaaatgcta aaaatgatct cttagatgaa agagcctatg agctaggagc
    18421 ctctgatttg tatagccaga cagttgcccg ctgctacaag gcctatcagg aggagctcag
    18481 acgaagtgag gctatggatt ttgatgattt gattatgatg accttacgcc tatttgatca
    18541 aaatcctgac gttctagcct attatcagca gcgttatcaa tatatacatg tcgatgaata
    18601 ccaagacaca aaccacgctc aatatcagct agtgactctt ttagcctcac gctttaaaaa
    18661 tatttgtgtt gtcggtgatg cagaccagtc catttatggc tggcgtggtg ctgatatgca
    18721 aaatatttta gattttgaaa aggattaccc tgatgcaagg gtggttttgc tggaagaaaa
    18781 ttatcgctcc accaagaaaa tccttcaggc agctaacgag gtgattcagc ataatcgtca
    18841 tcgtcgtccg aaaaaattgt ggactcaaaa cgcagacggt gagcagattg tttattatag
    18901 ggcaaatgat gagcgtgacg aggctgtttt tgttgcctca accatcagca atatgtgtct
    18961 agagctagga aagagcttta aagactttgc tgttttatat cgtaccaatg ctcagtcccg
    19021 tacgattgaa gaagccttgt taaaatcaaa tattccctac acgatggtcg gaggaaccaa
    19081 attctacagc agaaaggaaa ttcgtgatgt gattgcctat ttgactgtgg ttgctaatcc
    19141 gtcagataat ctctcctttg aacgaattgt gaatgagcct aaacgagggg tagggccagg
    19201 aaccctagat aagctccgcc aatttgctta tgggcaagga cagtcattgt tagaggccgc
    19261 ttcaagcctt gagcaatcac cgctaaaagg aaaggctgcc caagccatgc tggccttagc
    19321 gagtctctta agtgatttga gagctgattt agaccagctg agcattacag ccctggccga
    19381 ggccttgctg gagaaaaccg gctatctgga tatgctgcgc gtccaaaata ccttagaaag
    19441 tcaagctagg attgaaaata ttgaagaatt cctgtctgtt accaaaagct ttgatgacct
    19501 atcagcacag cagcaggagc atgaagcagg tattgatcgc ttaggaagat ttctcaatga
    19561 ccttgctttg attgctgata gtgatgatgg caatgcagaa accgctgagg taactttgat
    19621 gactctgcat gcagctaagg ggctagaatt tcctgttgtt tttctcatag gtatggagga
    19681 gggagtcttt cctttagccc gagcagccga ggatcaagat gagctagaag aagaaaggcg
    19741 actagcctat gttggcatta ccagagccga ggaatgcttg tttttaacga atgccaatac
    19801 acgtacccta tttggtaaaa gcagctataa tcgcccaaca aggtttttaa aagagatgtc
    19861 agagaacctt ttaagcttcc aaggcttggc aagacctgct catgcttcct ttggtgtgac
    19921 attttcgcag cagggtcaac gacaatttgg cacaggaatg agtctatcag aggctatcca
    19981 gtccagaaaa tcaatggcac agcctgccag agcagcctca acatctacac cgctgccctt
    20041 tggaccgaat gcagctactt caaagcaagc cgttgattgg cagattggtg atattgccca
    20101 tcataaaaaa tggggtgctg gaacggtttt agaggtcaag ggatctggta agaccatgga
    20161 attaaccatt agttttcctg atgtcggatt aaaaaaactc cttgccagcg ttgctcctat
    20221 tgaaaaaaaa taaaaggtac agcttatggg caatttgcat agtcacttgg ataagggctt
    20281 tgcaattgcg gtttagttct gcgatttaag aaaagaagta agcaaggatt ttatcagtta
    20341 accacatacc aagcttttga tggccttgat gccggagaga gcttggtatt tttttatttt
    20401 taaaaaaatc acaaaaaatg atttattctg agcataatcc ttgcaaatta aaatgagaag
    20461 tgtataatgg caata
//
LOCUS       DARYLD010000037        20405 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYLD010000037 DARYLD010000000
VERSION     DARYLD010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20405
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(85..1350)
                     /locus_tag="TU651_001258"
     CDS             complement(85..1350)
                     /locus_tag="TU651_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL0897261.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TU651_001259"
     CDS             complement(1364..2221)
                     /locus_tag="TU651_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897262.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TU651_001260"
     CDS             2564..3856
                     /locus_tag="TU651_001260"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL0897263.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TU651_001261"
     CDS             complement(3971..4744)
                     /locus_tag="TU651_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL0897264.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TU651_001262"
     CDS             4869..5615
                     /locus_tag="TU651_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0897265.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TU651_001263"
     CDS             5630..6610
                     /locus_tag="TU651_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL0897266.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TU651_001264"
     CDS             6849..7169
                     /locus_tag="TU651_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL0897267.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TU651_001265"
     CDS             7194..7502
                     /locus_tag="TU651_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0897268.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TU651_001266"
     CDS             7513..8817
                     /locus_tag="TU651_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL0897269.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TU651_001267"
     CDS             9098..11515
                     /locus_tag="TU651_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL0897270.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TU651_001268"
     CDS             11530..12198
                     /locus_tag="TU651_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL0897271.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     AEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TU651_001269"
     CDS             12323..13414
                     /locus_tag="TU651_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL0897272.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TU651_001270"
     CDS             13921..14973
                     /locus_tag="TU651_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL0897273.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TU651_001271"
     CDS             15002..15580
                     /locus_tag="TU651_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0897274.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15779..16687
                     /locus_tag="TU651_001272"
     CDS             15779..16687
                     /locus_tag="TU651_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0897275.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16923..18269)
                     /locus_tag="TU651_001273"
     CDS             complement(16923..18269)
                     /locus_tag="TU651_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0897276.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19309..19413)
                     /locus_tag="TU651_001274"
     CDS             complement(19309..19413)
                     /locus_tag="TU651_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL0897277.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19793..20308)
                     /locus_tag="TU651_001275"
     CDS             complement(19793..20308)
                     /locus_tag="TU651_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL0897278.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHDS"
BASE COUNT         5782 a         4094 c         4555 g         5974 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaaagta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggcaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aaacaaaacc tcggagacaa actagccagc agctatttct catgagtaat caacatgtta
    15721 aaatcttctt tggagatatt agacaaccat aattattata tcatcaaagg agagaaagat
    15781 gacaaacaaa acaaagcgta caggattggt acgcaagtac ggtgcctgct cagcagctat
    15841 cgccttagca gctcttgcaa gcctgggagc aggtaaagca gtaaaggcag accagccagc
    15901 agcactaaaa tatccagaac ctagagacta ttttcttcat actcgtgaag gtgatgttat
    15961 ttatgatgag gatataaaaa gatattttga ggatttagaa gcctatttaa cagctagact
    16021 tggtgggatt gataaaaaag tagaagaagc tgcccaaaag ccaggtattc caggtcctac
    16081 tggccctcaa ggtcctaagg gagacaaagg agatccaggt gcccctggtg agcgcggtcc
    16141 agctggacca aagggcgata cgggcgaagc cggaccaaga ggtgagcaag gcccagccgg
    16201 acaagctgga gaacgtggac caaaaggaga tccaggtgct ccaggtccta aaggtgaaaa
    16261 gggtgatact ggtgcagttg gtcctaaagg tgaaaaaggt gataccggag caaccggacc
    16321 aaagggagac aagggcgaac gcggtgaaaa aggcgagcaa ggccaacgtg gcgaaaaagg
    16381 cgagcaaggc caacgcggtg aaaaaggcga gcaaaaacca aagggtgatc aaggaaaaga
    16441 tacaaaacca tcagctccaa aagcacctga aaaggctcct gcaccaaaag ctccaaaggc
    16501 ttcagagcag tcatctaatc ctaaagcacc agctcctaag tcagcaccaa gcaaatcagc
    16561 ggcaccaaca ggtcaaaaag cagccctacc agcaacaggg gaaatcaacc acccattctt
    16621 cacccttgca gctcttagtg tcatcgctag cgtaggcgtc ctaactctaa aaggaaaaaa
    16681 agactaagct agttattgta tctttcctgt atgacactag ctaacagcta atcacaaaca
    16741 ccagagagag gtcttttctg acctctcttt tatatacact gagcacatgc ttacctcaaa
    16801 aagacagtag tctaagtttg actactgtct caaaaatcat ttttatctaa agctttgatc
    16861 agcttgacaa atggtagaga aggacttgat ttctaaggcc tttgacctca gtttgacttt
    16921 tgttaatttt ccttacgttt tatagctgct acaccagctg tagccataac tgcaagtgca
    16981 gctgcggtga agaatgggtt cacagcctca cctgttgctg gcaattgatt agtcgttttc
    17041 ttcatctcag ctttagctgc tgctgcttta gaagctgtgt gagctggcgc tgctacttta
    17101 cctgcttgat cagctttttc aggactgagt ggtttagcct ctggcttagt ttctggtttg
    17161 gtttctggaa ctttaggtgc gtcttcttgt ggttttgaat gtggacttga ttttttaata
    17221 tctttagcat ctagggcaac gcttctttcc tcacctgttg tagcttgaga aagctttttg
    17281 ccgttgacaa aaatctcata gaaagtgcca tctagaagcc ctttagaaaa tacagctttg
    17341 ccatcagctc ctgttgttac tttctctatc acacgaccta ctctatgctt tagagtgact
    17401 tcttgtcctg ataaaggttc agcatcttca ttacgaacga taacaaccaa aggtgtttta
    17461 ctgtattctg gctcaactgt tccttttccg tcaacagtaa agctagctga atgcttgtcg
    17521 ccatcaacac ctgttcgtac agtatagcct tgaggaacgc cattcacaaa aattgataaa
    17581 cttcttccta aaggaagctt gtcaaaaaca gcttgtcctt tttcatctgt tgtcacagtc
    17641 gcaagtgttt ttctgccact tgttatatct accacttgga cgtcttttcc agataatact
    17701 ttaccctcag ggtctataac tgttgcggta aaagcaaagc taccttcaat aacatcatca
    17761 tgatggtggt gtgcatgatc actgtgatga ctactctgcc catcgtcaaa aggcttagaa
    17821 acatcaatct tatccaataa aataacatga tgatgatcgt catgtggata catcaaggcc
    17881 ttaccctctg aagtatccaa taattgaatc ttgtctaatg gcaagcctgt atttttggcg
    17941 atataagctt tttttacggc aataatatct tcagctgatt gattagtgtc tagcggtaat
    18001 ttatcagctg ctgctacagg atttgcggtt tctgatgctt ttgtaattgg tttatcagcc
    18061 atcacctcag tgctgtcaga taactgttga ttagctgtat ctgcagtatc tttatcctca
    18121 cctaacctcg gttggactac agtgtgatta tccactgctg gtgattcatc agcaaatgct
    18181 actgacgagt tagttgacat cgctaaacca gcagccatta aagcagctgg gataagtaaa
    18241 gagtatcggg taacttgatt ctttttcatt aataactcct tataactatt attcatttta
    18301 attaattaac cagttaacta tatcaatcta tcaaaaaaaa tatagtatgt caacctctta
    18361 aagtgattta atcagaacaa acgtatgaag aaaatcattt ggtgaaaaag aagcttattt
    18421 tagctgaaat agatccatta taaaagaggt gtcgtgaagt aactcaatat tcacctattt
    18481 ttgtcgcaag tattctaata ggaatagaaa aagggcagtt gcttgcaaca actacccaat
    18541 gtaaaaccgt taaagacggt gacagaaaat aactgttaac tgaactacct caaaagttaa
    18601 accaaagatc taaccgttgg atgttggttt gtagagcggt tattttttta ttgttatgtt
    18661 tacaacgact aagctcatca gtgtaaggga aagggacttc catattaaga agtatatata
    18721 catcctagat gagacgtgta atgaatgggt tgaacaaata gttgcttaat tttgggataa
    18781 gggttataat aaaaatagaa aaagggcagt tgcttgcaac aactacccaa tgcagaaccg
    18841 tttgagacgg tggctggttt tatagttaaa agataaccgt taactcgcca aagttaagga
    18901 cggttatttt ttattgtcat ctttgaagat ttgatagcac aagctgataa gcgcaatagt
    18961 aaagctacta aagcctaaaa ggatttatac cacttcaaaa gctgtcaatg ctttgactca
    19021 tcctttctgt tagattttga tgaactgccc ataggcctca cctacctttc agaaataaga
    19081 gccaccgtct taacctttct gctttatcat tatagcatat tgttattaag gttgactatt
    19141 cagactcgtc taaagaagtg taatagttgc ttaattttgg gataagggtt ataatgaaaa
    19201 tagaaaaagg tagttgctcg acacaactac ccatgcagaa ccgtttaaga cggtggcatg
    19261 ttttatgtta ttaaaaaata accgttaact cgccaaagtt aaagacggtt attttttatt
    19321 gtcatctttg aagatttgat agcacaagct gataagcgca atagtaaagc tactaaagcc
    19381 taaaaggatt tgtaccactt caaaagctgt caatgctttg gctcctcctt tctgttagat
    19441 tgtgatgaac tgcccatagg cctcacctac ctttcagaaa taagagccac cgtcttaact
    19501 tttctgcctt tttattatag cataccctat ctctgattga ctagcttaag aaggagggga
    19561 tgtgatttgg atacaaattt ttgttaactt ttttaaagtc tccaaatgat ttaaaaaaat
    19621 gatattaatg ctctaagtaa gaatattaat aatatggttt taccacttat tgtatgaggt
    19681 atcatttcta aagagttatt tttcagacag aaggcttgtt aaagcaaaca gaagcaatac
    19741 taaaggcatt agatgataat caaggccttt ttcatgtctt aaaatgagta tactagctgt
    19801 cgtgttggat agaattcata taatgattta actgcttttg attttttaaa acgattgttt
    19861 tatgaggata ttgtttaata actgctttat agttatttaa attatttttt gagcgtccgt
    19921 ctaacagaat ccatttcata aattcaacat caaatttttc attacagttt tcagccatat
    19981 caggacgtgt ttgtccccta tattttaaat atcgcttaaa agctcggtaa aaacaattaa
    20041 atctattaaa gttaaaatat ataatgtgat cagcctctct catacgctct tcataaagac
    20101 agcttgaata attaccttca ataatccaat gtttttgtga cataaatgtt gatatatcag
    20161 agaccatttg actaactgtt cgctcttgcc agtttgatgc aaaatgaatt ttgtctaaat
    20221 gaagtacagc acaattgtag tgttgaccta aaacatttgc taaagtcgac tttccagaac
    20281 cactatagcc aattattaca attttcaatc tttgtctcct ttgtcaatgc tgtactttga
    20341 cttatattat agcataaaga atatattttg gggacaaatc ctctttagac aagcaaaaaa
    20401 gcctt
//
LOCUS       DARYLD010000038        19641 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYLD010000038 DARYLD010000000
VERSION     DARYLD010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19641
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..1230
                     /locus_tag="TU651_001276"
     CDS             <1..1230
                     /locus_tag="TU651_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL0897279.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKL
                     IFPKYEKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNL
                     TNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLL
                     QYDWIVDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLD
                     KKQSNSFNIFRKAGFGL"
     gene            1242..2744
                     /locus_tag="TU651_001277"
     CDS             1242..2744
                     /locus_tag="TU651_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL0897280.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2725..4302
                     /locus_tag="TU651_001278"
     CDS             2725..4302
                     /locus_tag="TU651_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL0897281.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            4304..4510
                     /locus_tag="TU651_001279"
     CDS             4304..4510
                     /locus_tag="TU651_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897282.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            4507..4926
                     /locus_tag="TU651_001280"
     CDS             4507..4926
                     /locus_tag="TU651_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0897283.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            5123..5392
                     /locus_tag="TU651_001281"
     CDS             5123..5392
                     /locus_tag="TU651_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897284.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            5428..5595
                     /locus_tag="TU651_001282"
     CDS             5428..5595
                     /locus_tag="TU651_001282"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897285.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5777..6400
                     /locus_tag="TU651_001283"
     CDS             5777..6400
                     /locus_tag="TU651_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL0897286.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            6411..6791
                     /locus_tag="TU651_001284"
     CDS             6411..6791
                     /locus_tag="TU651_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL0897287.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6794..7843
                     /locus_tag="TU651_001285"
     CDS             6794..7843
                     /locus_tag="TU651_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL0897288.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7854..8120
                     /locus_tag="TU651_001286"
     CDS             7854..8120
                     /locus_tag="TU651_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897289.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            8130..8483
                     /locus_tag="TU651_001287"
     CDS             8130..8483
                     /locus_tag="TU651_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL0897290.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            8480..8788
                     /locus_tag="TU651_001288"
     CDS             8480..8788
                     /locus_tag="TU651_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897291.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8769..9134
                     /locus_tag="TU651_001289"
     CDS             8769..9134
                     /locus_tag="TU651_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL0897292.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            9131..9520
                     /locus_tag="TU651_001290"
     CDS             9131..9520
                     /locus_tag="TU651_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL0897293.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            9530..10121
                     /locus_tag="TU651_001291"
                     /pseudo
     CDS             9530..10121
                     /locus_tag="TU651_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            10183..10542
                     /locus_tag="TU651_001292"
     CDS             10183..10542
                     /locus_tag="TU651_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL0897294.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10584..10913
                     /locus_tag="TU651_001293"
     CDS             10584..10913
                     /locus_tag="TU651_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897295.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10930..14184
                     /locus_tag="TU651_001294"
     CDS             10930..14184
                     /locus_tag="TU651_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL0897296.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            14216..14995
                     /locus_tag="TU651_001295"
     CDS             14216..14995
                     /locus_tag="TU651_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL0897297.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14992..17049
                     /locus_tag="TU651_001296"
     CDS             14992..17049
                     /locus_tag="TU651_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL0897298.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            17049..17756
                     /locus_tag="TU651_001297"
     CDS             17049..17756
                     /locus_tag="TU651_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0897299.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17758..18372
                     /locus_tag="TU651_001298"
     CDS             17758..18372
                     /locus_tag="TU651_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897300.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            18383..>19641
                     /locus_tag="TU651_001299"
     CDS             18383..>19641
                     /locus_tag="TU651_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0897301.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDA"
BASE COUNT         6635 a         3430 c         4416 g         5160 t
ORIGIN      
        1 tttaataagc atatttatga taaattatat gactatgaca cttttacaga ggtccattac
       61 ggcggagcat cgtctggtaa atctcatgga gttattcaaa aagtagtatt aaaagcatgc
      121 caagactgga agcaccctag aaaggtgctt tttttacgca aagttggtgc aactgtttat
      181 gactcaatat tcgaagatgt gaaacagtgt cttgagttat ggggtctact agacaagtgt
      241 aaggttaata attcagcata taggattgag ctgccaaatg gggcgacatt tatttttaaa
      301 ggcctagaca accctgagaa aatcaagtca attaaaggcg tgtcagatgt cgttatggaa
      361 gaggctagcg agtttacgct tgatgattat actcagctaa ctcttcgtct gcgtgatcgt
      421 aaacatttaa agaaacaaat ttttttaatg tttaacccgg tatcaaaagt aaactgggtt
      481 tataaagcct tcttcgttaa gacacctaag aatacagttg tctatcaaac aacttataaa
      541 gacaaccgtt tcttagatga tgtcacgaga gaaaatatcg aggaactagc caataggaat
      601 gaagcttatt acaaaatata tgcccttggc cagtttgcga cattagataa gcttatcttc
      661 ccaaaatacg aaaagaaaat attaaataaa gacaaattat cacacttgcc ttcttttttt
      721 ggcttggact atggatttat taatgatcca tcggcatttt tgcatgtcaa aattgatgat
      781 aacaataaaa aactttacat cttagaggag tatgtgagaa aaaatctaac aaatgataag
      841 atagcaaatg ctataaagga cctcggatat gccaaagaag agattagggg agactcagca
      901 gaaaagaaat caaatcaaga gcttagaaat ttaggtatcc caaggataat cgatgttaag
      961 aaaggtccgg ggtctgtcat gcaagggatt cagtatctgc tgcaatatga ctggatagtt
     1021 gatgaaagat gtgtcaagac cattgaagag ttagaaaatt atacctggaa aaaagataaa
     1081 aaaacaaatg agtatattaa cgacccagtc gatagttata accactgcat tgacgcgatt
     1141 aggtatgcga catctaatca tttcttgaca ctggacaaaa aacaatccaa tagctttaat
     1201 attttccgca aagcaggttt cggactctag aaaggagaac aatgttatac acagaaacgt
     1261 ttaaagacag cacaggtaat gctaaattac ttgagtttag attccatcgt gagtctcgta
     1321 tgaggtatca gacaagcgat ttaagcggcc tttttgacga agggtataaa ctattgcttg
     1381 actatatcaa acaccacgaa agcaagcaaa aaccacgcat acaggagctt ttagactatg
     1441 ctgagggtaa taatcataca gtctgcgaat caggccgcag acgagaggct gatatggcag
     1501 acagtcgtgc tatacacaac tacggtaagt atatctcgac ctttaagcag ggctatttag
     1561 ttggaaatcc tatccgcgtg gaatatgagg acaatgatga tgctaaaaaa caattgttca
     1621 aggagctggc ggataaaaat aacttccacc aacttaaccg tagacttgtc aaggatttat
     1681 ccaaggtagg ccgcgcctat gaacttatct atcgcagcat ggacgataag acagaggttg
     1741 tgcgattaga tccacgagaa acctttatta tctatcaagc tgatgttggg caagctagcc
     1801 ttgtgggtgt gaggtactat aacaagagtc agctggatag aacaaagaaa acagttgagg
     1861 tctacacaga taacgagatc atttactttg attatgatgg gcaactgaca gaggttgata
     1921 ggcggccaca catttttaaa tctgtaccta tcacagagta tctcaatacg gacgatggcc
     1981 ttggtgatta tgagacggag ttgtctttaa ttgacttgta tgatgcagct caatcagaca
     2041 cagcaaacta tatgcaagat ttgtcagatg caatcttggc tattattggt cgagtatcgt
     2101 tcccgagtta tgtagacacc aaggaaaaag ccattgaata tctgcgtgct atgcgcaaag
     2161 ctaggttgct aaatttagag ccaccagtgg ataccgaagg tagagaaggt tctgtagatg
     2221 ctaagtatct ctataagcaa tatgatgtca acggcacaga agcttataaa gatagggttg
     2281 tgcaagatat ccacagattt accaacacac cagatatgtc agatagcaaa tttgcaggca
     2341 cgcaatctgg agaggcactc aagtggaaag tctttgggct tgaccaagag cgtgtagact
     2401 tgcaagcact gtttgagcaa tctctaaaac gtagatataa gcttatcgca agagttagtg
     2461 agctgttaaa agaaattgac ggatttgaca ttagcaaact taaaattact tttaccccta
     2521 acttaccaaa atcgctacat gaaaaaattg aagcttttaa agcacttgga ggggagttgt
     2581 cgcaaaaaac aacaatgtct attacagata ttgtggaaaa tcctgataaa gagattgctt
     2641 ccatcaacga tgaggctaaa aatcgtagtt tattggcgca aaagatggag tcagaaggta
     2701 gaatgacgga tagggagtta gctcgtgact acaatcatga ataagagtaa atattggcgt
     2761 gatcgtgtta aaaaagaaat ggacgcaaaa gaggcagatg atatctccct tgaacagtcc
     2821 atgaaacaat tacacaatta tcattttaga aatatcgaaa aagaaattga gtcattttat
     2881 caacgttacg ctgataaaga gaaaatagac atcgcagaag cccgtaagag agtttctgag
     2941 cttgacattt ctgcttacca gaagaaagct aaggaacttg ttgtaaaggc tgagaagcta
     3001 cgaaaagagg gtaagacagt aacgagagat gactttaccc accaagaaaa tgcagacatg
     3061 gccatctaca atttagcgat gaaaactaac gctttagaat tgttgcgctt gaatatcgac
     3121 ttggagatgc aggagctcgc aaatggcgaa cataagctaa ccaagacatt tcttgacgaa
     3181 ggataccgca aagaggttga gttccaagcg ggattgttag gactgtcggt tgctagccaa
     3241 gcaagcgtga aagggttggc tgacgcagtt attaacgcta atttcaaagg cgcaaaatgg
     3301 tcggatagca tttgggacag acaagataaa ttacgcagca ttatatccca gagcgtacag
     3361 agtgctatct taaaaggtaa aaatggttta actattgcaa gggatattag acgagagttt
     3421 gatgtgtcag tgtcttatgc aaagcgaata gcaatcactg agcatgcaag ggtgcagatg
     3481 gaagttagta gattatccat ggcggagaat ggctttgcta tgtttgacat tatcccagag
     3541 cctaaagcat gtgatgtttg taaagacatt gctaaacaag gtccatatca catggataag
     3601 tggcgaacag gggaaaacac gccgcccatc catccttatt gcaggtgtgc agttgttgga
     3661 gtggaagaag aaaatagtag taatcatgaa tcacttgata agcttattaa aacagagtat
     3721 aatcaaagta tgaaagagtc atcgacttat gctcgtaacg ttttgtcggc agtgtcattg
     3781 atagagcctc gaattacatc gcaaattaag catattgtca agcaatccaa cggtaattta
     3841 caaggacttg attttagatt aaaaagtcta gattctttgg ccagaaagat ctctactgat
     3901 agcttgttgg acgatatttc accggaagaa gccgcaaaca acataaatga tgcattacgc
     3961 tatacagctg tatttaaacc agataatttt tttgatgatt atcatagcat gaaaaatgca
     4021 ttggtcagag atggttttaa aatcgaaaag gtgaaaaata cttggctaga tgatggtcca
     4081 tataacggtg ttaatactgt tgtatcaaaa gacaatgtca agtttgaaat tcaatatcat
     4141 acccaagaaa gctttgattt aaaaaacggg aaactgcatg aattatatga ggagagaaga
     4201 cttcctaata taacacgaaa acggaaggct gaactagaca aaatgatgtt tgagcttagt
     4261 aaatctttaa ctaaacctaa ccaaatagaa agggtgaatt gatatgatta caaaatattt
     4321 ttttataaaa accgaacacc ccaaaattgt tagatattct aatgggttaa cagaagttta
     4381 taacagcgca aaaggctggg aagaacaaga agcttggtac gatcgtctat tctttagcga
     4441 tttcagtgat tttgaagagg ttacagaaaa agaagctaaa atgtttattg cgggattgac
     4501 agcggcatga gtattgtgga gctagctttc agagtggcta aaaaagccca ccttggacag
     4561 gttgataagg ccggtgtcga ctatattaag caccctataa ctgttgcaag ttttgtaaaa
     4621 actgatgaag aaaaggcaac ggcttatctt catgatgtta tcgaagatac aagtttgact
     4681 ttacttgact tggaagagta tgattttcct cgaagtgtta tagaggcagt tgatatactg
     4741 acaaagaaaa aaggacagga ttatcaatcc tatctaaacc ttgttaaaac aaataaactt
     4801 gcaagaactg taaaattagc tgatttaaaa cacaattctg atttatctcg tctctctgaa
     4861 gtaactaaca aagatttaaa acgctataaa aaatatcaag aagctatcaa atatttaaac
     4921 aattaaacaa caacagacgg gcaaccgtct ttttttgtac cccaaaaaca ggaggaaatg
     4981 atgttgaaaa tagtgaaatt tttgaaatat gtttggattt ataagtgtaa acctgtcagt
     5041 ccaagtcttt atgcatcgag tcggattgag tacttcaaac ctcttggtta ttactgggaa
     5101 aaagcaacga taggagaaag caatgaataa acgaatcaaa aagaaacgta aactagaaac
     5161 agtagtagtg atgctggttg cggaaaatgc cttgcaggct gaagcgctca taaatcaaaa
     5221 caaagaaatc atggagctaa aatcaatcgt tgagcgaaac gctctggcaa caaacgaaga
     5281 gttagcgact gttaaagaca ccgttttaga caaccaatca gttatcaagg caattggtga
     5341 cacggttgac tacatcaagc aaaattacaa acgtaagtgg gggaagaaat gaagtatctc
     5401 aagaaaaagt aatagtaagg agttattttg aaagtcaaag agatagcaca ggtgtttaat
     5461 gaatattcgg atttttttgt ggtacaaaac ggtaaatatc tacctggtga cagaactagt
     5521 ttttttctag attgcgaatt ggaaatcaaa gaaatatcta tcggaattcc tgattgctta
     5581 attattgaag tataaaaaat tcaaagtcgt agcaatacgg ctttttattg tgccctgagc
     5641 atggcctaaa aaggctcaaa ttaatcacta gcgtggcttg tggataaata cacctaatag
     5701 agactagaaa acatgaggcg cccgttttcg tggctctgca gtgtgtttaa aagcaagact
     5761 agcgtgggag gaaaaaatga ataaaaaact attagaaaaa ctttttaaat gtgctccaga
     5821 tactggcaca ggttcaggag gagcttctga tgcagatagc caacaatccg aaacagatgg
     5881 agaaccatct agtgaagaca gctttaaagc tccacagtcg caatcagagt tagatagcta
     5941 tacgaataaa gcaatccaaa aggcattgga aaatcaacgc aaagatgaag ctaaacgaat
     6001 agaagaagct gtaaaagctg ctttagataa agaaaaagac tactccaagc tatctgaaga
     6061 agaacgtcag cagcgtgaat ttgaagatag taagaaagcc tttgaagctg aaaaagccaa
     6121 gtttgaacac gataaacttg tagtccaagt cgaaaaggat cttatcgcaa agggattgcc
     6181 ttctgagttt gctgaattgc ttgctacaaa agatgcagaa aatgcgctag agcaagtcaa
     6241 aacattcgaa gcagcattta aaaaagcagt agctgatgaa gttaaaaaga ccgtacgaca
     6301 acttactcca tcaactgggg caggtgcaat atcaacacaa acaaactatg gggcgaactt
     6361 ggcgagtaag atcgcacaac aaagcaccac attattttag gaggaaaaaa atgaataaac
     6421 gtaaagtaac aacatcaaaa gagattctcc acaatctcga atacgaagct attacagtca
     6481 ctttagattc aagcacagtt ggcaaaaaag ttattccagc cggtacagtt ttggccggtg
     6541 tatcggattc tgtttttaaa gatcgcaaac aaaaagtaaa aactgtggca aatcacgagg
     6601 tcagcggaga gagcaatatt tgtggaattt tgttaaccga tgttgatttg acagatggtg
     6661 ataaagcagg tgcttgtgtt tatcgcggta ctgtcaacgc agataaactt gctgattcat
     6721 caattgcaga aaattttacg gaattggcga caaaactacc acatgttgtc tttattaagg
     6781 gaggtaagta agcatggcat tgatccacga aattatcaca tcggaaaaca tcaaaggttt
     6841 ttataatgct aaaaatgaga acattgataa aacgttaggg gaaaaagcat tcccaccaaa
     6901 acagcaatta gggcttaagc tatcctttat caagggtgcg gcaggaaaac ctgtgacact
     6961 taaagcggcc gcttttgata ctaaagtacc tctacgtgac cgcatggcag ttgagctgct
     7021 tgacgaagaa atgccttact ttaaagaggc tatgcttgtt aaagaggcag accgtcaaga
     7081 gcttaacatt atatctcaaa caaaaaatag tgatcttatt gacacagttt tagcggcaat
     7141 ttataacgat aaggtaacgc ttatcgcagg cgctaaagca cgtttagaag caatgcgtat
     7201 ggaagtgctg tctaaaggta aaatccacgt cgcatcaaac ggtgtcatga aagactttga
     7261 ttatggacta gactcttcgc aaacaactaa gccaagtgtt aaatggtctg aggcagagac
     7321 cgcgacacca cttaaagaca ttgaaggtgc aattgaaaaa atggcagaac gtggctttgt
     7381 gccagaagca attatcatga actctaagac atttagtttg attaaaaacg ctaaatcaac
     7441 tcttaaaatc atcaaaccaa tggcaccaga tggggcagct gttaccaaag gtgatttgac
     7501 gacttatatt gctgatgaac taggactcaa aattttgttt aaagatggta tgttcattgg
     7561 tgacgatggc aaatctcgta agtatttccc agatggcttt gcaactttgg tacctaacgg
     7621 caaccttggc tacactgtgt ttggcactac tccagagcaa tcagatctca tgggtgggca
     7681 cgcaacagat gcagatgtgt cgttggttga gactggtatt gcaatcacaa ctactaagac
     7741 aactgatcca gtaaatgttc aaaccaaggt atctatgatt gctttgccgt cattcgaacg
     7801 attggaagaa gtgcaaatta tcgactccat tgaccaagta taaggagggg gttatggctg
     7861 aagttattaa aacttttagg gataaagaaa ccactaacac ttactacgta ggagacgatt
     7921 acaacggaga ccgcattgat gagttgacag ctaaaggata cctatctggt gataaggttt
     7981 ctgctgccgc tatagagatt gaccttgaca aattaaaggt tgacgaaatt agagcaaaac
     8041 ttgatgagtt aggcgtcgct catgacccta aactaaaaaa gccagaatta ttagaacttt
     8101 tgaaacagtc agctagctag gaggtgttta tgcaaaagat aaacacagat agcattatag
     8161 ctaacgtaaa actcgattta ggtattgatg acaccttgca agacagtttg ctcaatatgt
     8221 tgctaaaacg tgttacagac cattttaaag cggaatacgg cgttgatgat atagacaacg
     8281 ccttttcgtt tgttttggaa gactgtctaa ttgctaggtt taatcgcaga gggtcagaga
     8341 gggctaagtc ggaagaggta gagggtcata aaacaaccta ctatgacttt ttaaatgagt
     8401 ttgagcctta cgacaaaatg attaagtcca accttaattt gattaaggat aattctcgta
     8461 aagggggatt gtacttttta tgagatatgc agataggatt acgtttgtta aggcgacaga
     8521 tgaacaatat gaccctgatt taggtgagta cacatatacc gaagtcatga tcaagacatt
     8581 gccttgtttt gtcatggact taggtatggc taaatctgtg cagattttcg gagactatca
     8641 aaaaacacga aaagttgttt atttgcgcca accttatacc gatttgttag atcactgtct
     8701 ctacaaaggc aaaaagtaca aggtacaggt ggataagcaa tttaatactg ttttttatct
     8761 ggagggagat gattctattt gtagctgata tatctttaaa agtagttgga acgacagggc
     8821 taaagaataa acttgaactt attgccaaaa aagaggctgt caagaagatt gttagagata
     8881 atggaaaaca actacacagg aaaatggtcc aaaaggcagt atttaccaaa ggtcattcca
     8941 ctggtgctac cagaatatcc atcacaatgc agattggtga tgatggtttt agtgttacag
     9001 taaaacctgg cacgcattat gcaggttatt tagaaaaagg cactcgcttt atgagtaagc
     9061 aaccttttgt gttgccagct ctaaaagagc aaaaagtaaa attcagaaaa gatttggagg
     9121 cgcttgtcaa atgattaaaa ctagagatca atctattttt gacgagatgt ttaagcgtat
     9181 tcagtcttta ggttttaaag tttatgatta caaaccgatg actgaggttc cttatccgtt
     9241 tgtggaaatg gaatctactg atgcagaata tattccaaat aaagatgaca ttaaaggctc
     9301 tgttgacctc gtactgtctg tttggggatt gcaaaaaaaa cgaaagcagg tgtctgatat
     9361 ggcatctgct attttttcac aagctatgtc agtggctagt tctgacagct tttactggtc
     9421 gttaaatatt cgtcaatcat ctatccaagt gttagatgac acaacaacag tgacacctct
     9481 caagagagcg attgtcacat taagatttaa tttaagatag gaggtcgcaa tgccaggacc
     9541 aagtagatta ggatccaaag atgaagacca ctccacacaa gaaaggaagg aaaaaatggc
     9601 agcgcaagat caagtacaat tagaagcaaa acaagggatt catgcaatcc tattattccg
     9661 tttgttaaaa gaagcatcat cagaaaaagc agctaaactc gcttttcaaa cggaacacga
     9721 agttggtaaa agtcgtgatg tcgacggtca aaagactaaa gatggtatta tccagtctgt
     9781 cggagcttta gaatacgact ttaaagcaac atctatttta gccaaaggtg acaagttagc
     9841 agcaaaacta gaagaagcca tggaaaaagg tgagcttgtt gaaatttggg atattgattc
     9901 cgaaaaagca agtgaagaag cttgatagca aaggtaaata tccagctacc tattaccaag
     9961 gttacatttc aagtttcggc gctaagaaaa atgcagaaga aaatattgaa attgaaatgg
    10021 aatttgccat taatggcgtt ggtcaaaaag gatttgcaac attgaccgaa gaacaaaaag
    10081 cagctgtaca gtacaaattt aaagatacaa cagcaggtta atcaacaagg ccagttaatt
    10141 actggtcttt tatttttaaa tttttaaagg gggaaaagaa taatgcaatt ggaaattaaa
    10201 ggtaaaactc ataacatcaa atttggcaca cgatttgttg ctgaaatgga taagaatcac
    10261 attgcagaac gtgaagggat gaagtttggc gctggtttgc aatcaactgt tccgtttttg
    10321 tttgagcgta acgttgtgac acttgctgag attatctata cagggacaat cacagagtca
    10381 ccacgaccaa gcttaaatga tatttacgac tacatcgatg aggctgaaga tattgagaag
    10441 cttttcgatg atgttttaga tgagttgcgc caatctaacg cgtcaaagtt gtttatcacc
    10501 aaactggaca aaaacatagc ggagatggca accgaagctt aaagagttca accaaaaatt
    10561 attcttcaca agaaagcttt gagatgattg tccttaattg tgttagatat cttggcatga
    10621 ctgacattaa tgagattggt cggttgactt tgtatgaata tgatttattg atgataggta
    10681 aagcgctagc ctctgtagac gaggcatata aagctcacaa gcaagcttgg ataaatcacc
    10741 aggtctcagc tacgaggctg gtcggtggtg gtaaaaacaa aagagaagtt cctgtttata
    10801 aaacattcaa ggaatttttt gattatgaaa cagaaatcaa gaagataacc aatgaaattg
    10861 atgaaagcta tgacaagaaa gcaatggatt tacttttaaa agccaacctt taaatagaaa
    10921 ggaagttaaa tgggagaatc ttattcagtt gaagcggtgt tgacagcggt tgataaaacc
    10981 tttggtaaga ctttaaaatc agcagttcaa tcaattgaag gactagaaaa gcgttcaaaa
    11041 ggcttctcgg cggtgtctca aaaggctggg tctatgttta aaagcatgct tggagctaac
    11101 ttagcaggtc aagctattac agcgctagga cgtacagttt catctggact tatttcgatg
    11161 atcggcgaaa tgaatagctc agcaaaagcg tggaaaactt tcgatgccaa tttagcagat
    11221 atcggatttg gcaaacagca aattcttgaa gctaaaacag ctatgcaaga ttacgctact
    11281 aaaacaatct actcagcatc agatatggcc agcacatatg cacagttagc tgctgttggg
    11341 gtaaaggata ctgggaaact cgtaaaagct tttggtggtt tggctgcatc tgctgaaaat
    11401 ccaaaacaag ctatgaagtc aatcagtcag cagatgacac aagctgtggg aagacctaca
    11461 gtagcgtggc aagatttcag aataatgctc gagcaagctc cagctggtat ggctaaagtg
    11521 gccaaagcta tgggcaaaaa ccttaatgaa cttgtagccg acattcaggc tggtagagta
    11581 aaaactaaag acttcctaga agcagtaaaa caagctggta acgacaaaag cttccagaag
    11641 atggcgactg aattcaaaac tgtggaccaa gccattgatg gcatgcgtga aggtttatcc
    11701 aataaattgc aaccagcttt tgaaaaagtg aaccaatttg gaattagagc gattgaagca
    11761 atcgggaaac aactcgataa aatcaatttt tccaaatttg ctgcaggcct tggtaaattt
    11821 ctcgagggcg tgaacattga tagtattatt tcaagaatat caacatcaat ttcatctatc
    11881 gtttctaaaa taaaaggatt ctgggacgga tttaatcaaa ctggagcaat cagcgctttt
    11941 tccggtgctt tacaaagtgt ttggggagcg ttaaaaaata ctgctaaagc catgagtgga
    12001 ggaagctgga agaccttcgg gtcaatcatt ggcgaaattg ttaaacatgt ttctaatttc
    12061 gcaagagtga ttggagatgt cgttggcaag atggatccga gtagactaaa aagctggata
    12121 gctactcttg cagctgttgg tggtggattg aaaatctttg agaaattaac aggtcaaagt
    12181 gttattggat cttttttaga caaaatcggc tcaaaattca aaatatttgg aaataaagcc
    12241 aaagaaggga cagaacaagc ctttaacgga gtcaaaagaa gtggtggcat tatcagtaaa
    12301 atctttaacg gtttgggtaa tatcgttaag tctgccggta cagcgatagc gactgctgca
    12361 aaaggtatcg caactggttt ttctatcgcg tttaaggggc ttgggtctgc catttctatg
    12421 gtaccgccag ctacatggct agctttagga gcagctattt tagcggtagg agcggctttt
    12481 gccttggcag gaactcaagc tgatggcatt agtcaaattt ttaaaactgt tggcgatgtc
    12541 gttgtacaag ttttacaaca ggtcactaac agtctagcta ctctaattcc tattattgta
    12601 agcgctattg gctccatatt accaattgta gcaggggcta tttctcaagt cgtcgcagca
    12661 gttgctggcg gattatctca gattattaca gctgttgcta atggtgtatc aactattatt
    12721 ggggctttca caggtctact tggtggtgtt tctagcgtca ttacctcaat tagtggtgtt
    12781 atccaatcgc tggcaggtgt aattacctca gtatttaatg gcatagcaac cattatttcg
    12841 tctgtagggt ctgcaattaa agatgtatta acgggtctcg gcagtgcttt taaaggattc
    12901 ggcaacggtg taaaatcagc cttagaaggc gttgggacag taatcaaatc atttggtagt
    12961 gcagtcagaa atgtccttga tggtgttgcg catattttcg attctatggg taatgcagct
    13021 cttaatgctg gtcgtggcgt caaagaaatg gctaaaggca tcaagatgct tgtagattta
    13081 tcgcttgctg atttagtcgc aacgcttgga gcagtcgcga caggtcttgg gaatatggct
    13141 ggctctgccg gtcagatgac tacgttaagt tctgccatga gcgaagtagc caatggtatg
    13201 gcgcgtctag gaacaagcgc tacgatagca attactggat taacagtttt tgctactact
    13261 ataacaacta ttcagaccgc aattgcaact ctaccaacaa tcctaactgc agccgctagt
    13321 ggttttaggg agatcgggga ttcggcaact gcagcagttg gtcgaatcca gacttttgca
    13381 gctggtacaa ctgttgttgc atcagcgttt gctagtatgc aatctatgat tcgatctgcc
    13441 atggctgcaa tagtaagcag cattataaca tcatttaacc aagctgcctc tcaaatacaa
    13501 tcaattttat ctcgggtgct atctcaagct aggacatttg gatctcaact agagcaacaa
    13561 atgaggcaat cgggacagcg ttcaggacaa aatcttgctc aggggttgtc ttctcaacaa
    13621 ggtgctgtta ttaatgctgt ttctagcatg gttaatgccg cggtatcaag agcaaatgca
    13681 ggtgctagtc ctatgcgtca agctggagcg tacatcggac aagggcttgc gcaaggtatg
    13741 tattcagcgc taggagctgt aacagcagca gcaaacgctc ttgtagcaca agctgagagg
    13801 gcagcaagag ctaaggcgat gattcactcg ccatctaggt tatttgcaaa acgagttggt
    13861 caatatatcc ctcaaggggt agccatgggg atatataaaa acgctgatgt cgttgatgat
    13921 tctgtaggtg agctatttga tagtatcaat agctttgatt ttaatattgc ggatagattg
    13981 acaagtattg gcgctagatt ccaaggtgtt gtcaaatcag aaagttcgca atcgttgtcg
    14041 cagcaacaag agtttgtaca tacagctcaa ccagcgtatg taaactttag tttaggcgga
    14101 aacgaatacg aagcatttgt aagtgacatc actaatcgac aagcaaaaat tgaaaaaatc
    14161 agactaaaga gaagcagctg gtagttgttt ctcttagttt tatgaaagga gtaaaatgta
    14221 cgaatttaac gatactatca gagggactcc gaaagttact ttcaatttaa aaacaacaat
    14281 tggcgaaaag gtattagaag aagagctcaa taatgattta ggtaccttta ggacattgac
    14341 cgtttctggt cgtgatatgg tggacttaga acaccagaca acaagtgttt tagggcgaga
    14401 tggcgagtat ttccacaatg ccacagttga agtcagaaaa ctagaaataa aagctaaaat
    14461 tactggaaaa gataaccggt caatgcgttt gcaatatgaa aaattaaaca gattaattgt
    14521 tagtcataat caagtttttt tatcattttc agacgagccg gacagaaatt atctaggcat
    14581 ctttaaatct aaagatatac cagaagaagt ttctaacgaa caaatcattg gcttggtttt
    14641 catctgttat gatccattta aaatgtcaga tataaaaacc aaaaaaggta atactgttca
    14701 aaatgatggc ctatttaata caaaacctat cataactctc aacctctcat catcaacaaa
    14761 agaaattagg ctgctacacg tcgaaagtca aaagtatatc agattaactg gtacttatac
    14821 tactgacgaa atcaagattg atatgacaac aggtaagatt acccagaacg gccgtaatat
    14881 tcttagtgat ttagacatgg ttaacagtcg ctattttgat ctattacctg gtaaaaacac
    14941 tttgcagtgt gataatgcaa cgattacagc tgatttcagg gaggtttatc tatgatttat
    15001 ctctttgata agctggagca attagttgct actgttggta ctgatgactt gctctcatgg
    15061 cattttaagg tcaaaaataa tgattgggat caagctagtt ttgaggtacc tgttgattat
    15121 gacattgagc cttttgttta ctttggtttt tttaactatg atccaagcca aaaagaggac
    15181 gtttttaaac tctttaaagt cattgattac aacctagaag atagcaagta ttataaaggc
    15241 ttagataagg ctgagagtga ccttgatact attgctatta tcaaagacaa gcgctttaga
    15301 caatcgtccg cagatgcttg tattgatgga gctttagagg gcactggtta tcaagttggt
    15361 aaagttgagg gcatttccga gatcaggacc cttagctatt attacatcag cccacgagct
    15421 gccatgatca agatgataga agcttttaac tgcgaattta atgtcagata cacctttgtt
    15481 aataacaaaa ttactagtcg ctatatcgac cttaaaaagc gatttggcaa gccaacagga
    15541 aagcagtttg agcatgggaa taacttatta aaagtcgtct atgaggaatc aacagatgac
    15601 atcgtgactt gtctgattgg ccgaggcaag ggcgaggaaa tccaatatga tgaaccagag
    15661 gcaaaggaag ttgaaggaca cttaccagag gcagaaaagc gtcaaggtta tggccgaaga
    15721 attgaattta gcgatgttgt ctggtcagtc gaaaaaggcg actcgataga caaaccagct
    15781 ggtcaaaact ttgtggcgct agatagtgcc agagaagaat acggattgtc tcaaaatggc
    15841 gagctaaaac accgatgggg ggtctttgtc aacgaggaaa ttgaggacaa ggcggaactc
    15901 ttaaaagcca catgggatca attgcagcgc ttatcaatac ccatcagaat ttacaaggcg
    15961 gaaatcttag atattggccc cgaaacgtgg aaaggtgact cagtagccat tatctacgat
    16021 gaggtaaaaa tagcttttga aactcgtgtt gatgagattg atattgataa gctaaacttt
    16081 aacaggtcgg tagtaactct cggtgattat agcgttgtcc aaaaccgcga agcaaggtca
    16141 cgcaaggaag ctgtccaaaa catgatcaat gatagcatag aaaacatcac cggccttggc
    16201 atgaacttac aagaattttt tcaaggtatt gaggaaaaaa ttgccactgg caaaaaagag
    16261 atggaagaca attggcgtaa ggttaacctt gaatttgata actttaaaaa attaatcgaa
    16321 caagagggac gtaactttag agagcgttta gaagctgaaa caaaggaact agatgaacgc
    16381 aaccaaaaag aactcgatga atttcgcgaa accctcaaaa atctgtcgct gcccgaggaa
    16441 gccattaaaa aaataaccga ggccatcaaa gttgatgata tcccatcgct aaaacaaagt
    16501 tttgacgagc tcaaaaacga agtcagcaag aacagcgaaa aatctcgctt aaatgctgaa
    16561 atcatcggca cgaacggtaa gacccgctat aacaaaaatc tcttggttgg tgaacctaat
    16621 cgcaccaaga cctatgatca ggattttgtg gagatagaag caaatgacgg tggttttaga
    16681 cgcggtgaga catacacgat tagctttagt cagacatgtg agttgctaaa aaaagtggct
    16741 atcacgctga cgcagccgca taacaaaggt ctcaagctgg tgctgacacc aaccaaggct
    16801 aagatggagg cgcagacttt tgacctaacc aaggacatag aggttatcag cgtctatcct
    16861 ttgagctaca gagctgtttt aacaggtgac tggtataaat ctaagcagat ggattttaat
    16921 gcggcagaag tgcaggattt agctctggag atgtcttata gagacgttgt cgatagcaat
    16981 aatgctagtt tgattttgga ttggtcctca aatccagatg ttatttttga tggaaatgga
    17041 ggtagttaat gtcagagact atatcagcta tagttgtgca taaaagcatg acaaaaaacg
    17101 agtgggagtc tagtgacatc attttgccac aaggccagct tgtctatgag tctgacacag
    17161 gccatagtaa atttggcgac ggtaaaaata gatatgcaga tttgatctat caaggtggac
    17221 cacctggggc acaaggtccc caagggccag ctggcgaaac cggtccacaa ggcccaccag
    17281 gccctactgg tcaacgtggg gaaacaggcc cacagggtcc acctgggcca caagggccgc
    17341 caggagcgga cggtaaaatg acgtttgagc agctcacacc agagcaaaaa cagcagctta
    17401 aaggtgctgg catacaaagc atatcattgg attatgaggg ctatttgaca atacagctag
    17461 ataatggcca atcgtttaga tcagatatta gcttaaaagg tcctcaagga gagccgggga
    17521 tcaatggtat ggacggtcca agaggcgcaa cgggtcccca aggaccagct ggtgatccgg
    17581 cgagcatacc tgacgatgtt gtcagacgtg gtgagttagc tgcatatttg cttaaatcag
    17641 agtataaagc caaaggcgca ggctctgggc taagctacaa agttgtcact caatcagagt
    17701 atgatgatct gtatgattac agcgacaatg agttgatact cgtgacggag ggttgacatg
    17761 gcatataagc tttacactaa agctgatgtt ggtgacaaca tgttgcttgt tgttggccat
    17821 ttgcctgaca atacaaagcg attaaaaatc cagcgtgaga cgttagatgt attgagtatt
    17881 acccactata gctcttatga tatggtacaa ctcaagtcga cagtcaaaag atcccacagc
    17941 aaaaatacag ttgttactct tgtagctgca gctgctagca agcccaaagc taagccaaag
    18001 cacgttttaa actttgctaa ggctaataag gtctatctag gcagcactcg tgtaatagcg
    18061 gtttatctgg gtgatcgact gctctggtcc gacaaagaca gcagcgggaa caaaactgtc
    18121 tctgttgtgg ggagtcttga tatcagacaa tcacaaaaaa tgctgtattt gtacttaata
    18181 gcgtcagaca ttgcagatgt caaaagcaag cgcattaaat cgatagcgat aaatggcgtt
    18241 aacctgtcaa gcgctgcaca aatcaatttt gaggatagcg actattattg tctagtgaca
    18301 atcgagcgag ttgctaacat caaagagatc aaaaatatag cgcaaaaaaa caaaatcacg
    18361 ctagagtttt aggaggtaac aattgagcag agacccaaca attgtaatag acgagacaaa
    18421 cctcgttatt ggcacagatg gccgcatgca ttacacgttt actgctagtc aagacaacca
    18481 aaaggtcagg ctaaaaagca actgtttagg cacagcgcat tttaaccagc tgatgattga
    18541 gcgaggagac caagcgacgg actacgttgc gcccgttgtt gttgagggta caggacaggc
    18601 aacaggcgtc tttaaaagtc tcgaggagat gcttagtggc ctaaagtcaa ttaaactgga
    18661 gctaacagat accaaaaact caaatctgtg gtcaaaaatc aaattgacga caaatgggct
    18721 tttgcgtgag tatcatcatg atcatatctc gaccgagatt gtcgagacag cagctggtat
    18781 tgccaaacgg attgtcgatg atactggcca aaagctggca ctaatcaatg agactatcaa
    18841 aggtgttaag cgtgagtatc aagacgcaga tagacagcta tccgcgagct atcaagcaag
    18901 tatcgatggc ctcaaagccc agctggccaa cgacaaaatt ggcctacaag ctgagattaa
    18961 gctgtccgcc caaggcttgt cgcaaaaata cgacgatgag ctgcgcaagc tatctgccaa
    19021 gattacaacg acatctagtg gtactacgga agcctacgaa aacaaactcg agggcttacg
    19081 ggctgagttt actcgtagca accaaggcat gcggacagag cttgagtcgc aaatcagcgg
    19141 cctaaaagca gtacagcaat caactgcaaa acaaatctca caagagatca aggatagggc
    19201 aggggctgtt agtcgtgtgc aacaggatct agatagttac caaagacgct tgcaagacgc
    19261 agaggataat tacagtagct taacccagac cgttaaaggc ctgcagtcaa ctgttagcga
    19321 tcccaaaggc aaaatccagt cacgatttac acagctgcaa ggtcaaattg agcatcgtgt
    19381 gactagagat ggggttatga gtatcatcaa cgagtcaggc gatagcatta agctagcgat
    19441 ccaaaaggct ggtgggattg atgctaagat gagcgctaaa gagattatct cagcgattaa
    19501 tcttaatggt tatggcgtca gaatctccgg tgagcgtatt gcgctggacg gtaatacgac
    19561 cgttaacggg gcttttggag ctaaacttgg tgagtttatc aagctcaaag ccgatcaaat
    19621 tattggtggt tcgattgacg c
//
LOCUS       DARYLD010000039        19268 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYLD010000039 DARYLD010000000
VERSION     DARYLD010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19268
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            18..98
                     /locus_tag="TU651_001300"
     tRNA            18..98
                     /locus_tag="TU651_001300"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52..54,aa:Tyr,seq:gta)
     gene            105..175
                     /locus_tag="TU651_001301"
     tRNA            105..175
                     /locus_tag="TU651_001301"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:137..139,aa:Trp,seq:cca)
     gene            187..259
                     /locus_tag="TU651_001302"
     tRNA            187..259
                     /locus_tag="TU651_001302"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:His,seq:gtg)
     gene            268..339
                     /locus_tag="TU651_001303"
     tRNA            268..339
                     /locus_tag="TU651_001303"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Gln,seq:ttg)
     gene            358..441
                     /locus_tag="TU651_001304"
     tRNA            358..441
                     /locus_tag="TU651_001304"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:392..394,aa:Leu,seq:caa)
     gene            complement(785..1915)
                     /locus_tag="TU651_001305"
     CDS             complement(785..1915)
                     /locus_tag="TU651_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009855141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0897302.1"
                     /translation="MILRKYNDFCRLFLGRLISNCGDSIYTLVLSWYVLETTNSTWYV
                     GLLNFLIFIPNTFSFIFGKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLS
                     LTIIFSCVFLASMVGLNTYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISG
                     FLLSVISYIPLLFINIVTFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVL
                     AITLGGAIANFLFASLNVYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQK
                     LSVGKAFWLATTLLGTGIGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPD
                     EHLGEVFSAFYTVTIPTLALGSLILISLLYFSNKMLRQYDIC"
     gene            2480..3646
                     /locus_tag="TU651_001306"
     CDS             2480..3646
                     /locus_tag="TU651_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0897303.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQ
                     GQRGEKGEQGQRGEKGEQSQRGEKGEQGKDTKPSAPKAPEQSPAPQVPKTSEQQSASP
                     KVPAPKSAPSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAGLLTLKRKNN"
     gene            4140..4664
                     /locus_tag="TU651_001307"
     CDS             4140..4664
                     /locus_tag="TU651_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL0897304.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            4879..5730
                     /locus_tag="TU651_001308"
     CDS             4879..5730
                     /locus_tag="TU651_001308"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL0897305.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            5800..6243
                     /locus_tag="TU651_001309"
     CDS             5800..6243
                     /locus_tag="TU651_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL0897306.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            6246..6965
                     /locus_tag="TU651_001310"
     CDS             6246..6965
                     /locus_tag="TU651_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0897307.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKSRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            6958..7767
                     /locus_tag="TU651_001311"
     CDS             6958..7767
                     /locus_tag="TU651_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0897308.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(7802..9058)
                     /locus_tag="TU651_001312"
     CDS             complement(7802..9058)
                     /locus_tag="TU651_001312"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL0897309.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            9163..11463
                     /locus_tag="TU651_001313"
     CDS             9163..11463
                     /locus_tag="TU651_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL0897310.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            11725..15291
                     /gene="rpoB"
                     /locus_tag="TU651_001314"
     CDS             11725..15291
                     /gene="rpoB"
                     /locus_tag="TU651_001314"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0897311.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            15382..19017
                     /gene="rpoC"
                     /locus_tag="TU651_001315"
     CDS             15382..19017
                     /gene="rpoC"
                     /locus_tag="TU651_001315"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL0897312.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(19109..19268)
                     /locus_tag="TU651_001316"
                     /pseudo
     CDS             complement(19109..19268)
                     /locus_tag="TU651_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5363 a         3717 c         4710 g         5478 t
ORIGIN      
        1 gtaatttaat atgttttgga aagatagcga agaggctaaa cgcggcggac tgtaaatccg
       61 ctccttcggg ttcgggggtt cgaatccctc tctttccatc ctgaacgggc atagtttaaa
      121 ggtagaacta aggtctccaa aaccttcagt gtgggttcga ttcctactgc ccgtgttcag
      181 aatatggcgg gtgtggtgaa gtggttaaca catcagattg tggctctgac attcgtgggt
      241 tcgattccca tcactcgcct attttattgg ggtatagcca agcggtaagg caagggactt
      301 tgactccctc atgcgttggt tcgaatccag ctaccccagt ttagttttat acttaaagcc
      361 ggcgtggcgg aattggcaga cgcgctggac tcaaaatcca gtgtccgcaa ggacgtgccg
      421 gttcgacccc ggccgccggt atagtttaaa aatattgaaa aaacaaggtt tgtaaacctt
      481 gtttttttgt tttatgactt gatgtcagag gatcagattg gtcctctcta gatgttaaag
      541 gtaatgagaa tcttggcttc aaagctccta aatccaaagc attgcgcttg atgtctttga
      601 tcacctgtta gtggcgtgca gcttagcgtt tgaatttgga ataaggttgc tccaaggcat
      661 gtgtgatgtg agctttggat actaggactt ttagccaatt ctttgtgggt gagctttttc
      721 tttacgtttg gttttgatta atgtcgcaat atcagttatc atgtgttctc tggttaatga
      781 cgctttagca aatatcgtat tgtcttagca tcttgtttga gaaataaagc agactaatta
      841 agataagcga acccaaggca agtgttggga tggttacggt ataaaaagca ctgaaaactt
      901 caccaagatg ctcatcagga atctcagttc gtaaaatagg tttttgggta acatgcgtta
      961 ttccgagaaa tagacaggaa agaaaccaaa gaagcaacaa accaaaacgg ttggggacta
     1021 atgctgtaag gccaataccg gtgcccaaaa gggtagttgc tagccaaaaa gcttttccta
     1081 cacttaactt ttgcaagaca aggttagcaa caaaggttgt tcctaccagg gttccgatag
     1141 cacttacaga tactaagagg ccataaaaag ctgaattccc tacctctctt gctattaata
     1201 actgatagac atttaagctg gcaaaaagga aattagcgat agcacctccc aatgtgatgg
     1261 ctaacaccac tttattgtgc cagataaagc gcaagccact taaaaagtct gttcgttcat
     1321 ttgtttgttc aattatttct ttaaatgcta ttcttctaaa aaataggatt gaacctaaga
     1381 aggtaacgat attaatgaaa agcaaaggaa tgtagctgat cacagaaagc aaaaagccac
     1441 tgatggcagt aaaaacataa tctgttccat tataagccac tgacatatac atttctgctt
     1501 tagctagatc tttagtagga atgagtttag gtacaagagc atcttgaaca gtataggtat
     1561 tcaacccaac catagaagcc agaaaaacac aactaaaaat aatggttaag ctaagacttg
     1621 cgtgtatctc tcttaaggac attcctaaaa taatacctaa gacagccaat aattgggccc
     1681 actccagaat cactagcagg ttcttcttag ggtacgaatc aatctttttt ccaaagataa
     1741 aggagaaggt gtttggaata aaaatgagaa agttcaataa tccaacatac caagtactat
     1801 tagtggtttc tagtacatac caggacagca ctagggtata aatcgagtca ccgcaattgc
     1861 taatcagtcg ccccagaaat aaccggcaaa aatcattata tttccttaat atcatattgt
     1921 atcctttgat aaagagttta aacatctttt atattatagt atcagatgat aaaaaatcac
     1981 tgaatgatag ctgtgtttga tgtttgcaac attttaaaat atctttgcaa aaatcatacc
     2041 tagacacata caatcccaca taagttttaa aagcattcaa ttgcctttta agatctttat
     2101 gagtcatgtt tgtaaagata tcctcttgca acagatctct taatctctaa ttgtatccaa
     2161 taagaagcag ctttgtcaat acggaagccg aatagtcttt ttgcctttcc ttgtcagctg
     2221 ggcaatcatg agggctttgt gctttgatct tttgcatcta taaaagggtg aatctattga
     2281 tgaggtgtta tcggtagtgg ggcctactga tgtcaataac tgacgtcaga taattacctc
     2341 tttaattaga aaaaaaaaaa aacgaaacta cggagagaac ctaataactg gctatttctt
     2401 gatataagcc agcgtgttaa aatcttcttt gggagaaaat ttagaaaaaa ataatatttc
     2461 tatcactaag gagagaaaga tgacaactaa agaaaaacaa acaaaactaa tgcgcaggta
     2521 tggcattttc tcggtagtcg ttgccctaac agctctagca ggtctaggag cagctaatga
     2581 agttaaggca actgctaaaa aatctttaaa tgagttacct aatccagtag aaattattca
     2641 atataattca acaagaacta ctgatagaga agctagaaag tatcttaatc aattatatga
     2701 gtttttgaaa ccttatttag gaagtttaga agaagaagct caaaaaggag ggccacaagg
     2761 acctgtggga cctgctggtc ctagaggtga acgcggagaa ccaggaccta aaggagaccg
     2821 aggtcctgag ggccaaagag gtgagcaagg cccagcgggg cctattggac cccaagggcc
     2881 tcgtggtgac aagggtgaaa ctggagaaat tggacctagg ggagaacaag gtccgaccgg
     2941 tcctactggt aagccaggag agcgtggccc taagggtgac agaggcgaac gcggcgaaaa
     3001 aggcgagcaa ggccagcgtg gcgaaaaggg cgagcaaggc caacgtggcg aaaaaggtga
     3061 acaaggccaa cgcggtgaaa agggcgagca aggccaacgt ggcgaaaaag gtgaacaagg
     3121 ccaacgtggc gaaaaaggtg aacaaggcca acgcggtgaa aagggcgagc aaggccagcg
     3181 tggcgaaaaa ggcgagcaag gccaacgtgg cgaaaagggc gagcaaggcc aacgtggcga
     3241 aaaaggtgaa caaggccaac gcggtgaaaa gggcgagcaa ggccaacgtg gcgaaaaagg
     3301 cgagcaaggc caacgtggcg aaaaaggtga acaaggccaa cgcggtgaaa aaggtgaaca
     3361 aagccaacgc ggtgaaaagg gcgagcaagg aaaggatacc aaaccatcag ctccaaaggc
     3421 cccggagcaa tctcctgctc cacaggtacc aaagacttca gagcagcagt cagctagtcc
     3481 taaggtacca gcgcctaagt cagcaccaag caaatcagcg gctccagcag ctcaaaaggg
     3541 tatattacca gctacaggag agacaaatca cccattcttc acccttgcag ctctcggcgt
     3601 cattgccagc gcaggcctgc taactctaaa aagaaaaaac aactaaatta gcttttgcaa
     3661 ctttctccta ctaaatgata gcctttagct tgaaggcgat tgattagttt aaaagctgat
     3721 atgagcacta gagaggccct aatggggtct ctttttgctt gcagcagtag atgttttgtc
     3781 ttcctctttc atggggtgat gtagttggtg tgcttttggg ttgagccttt aaggtttttt
     3841 gtaactaata tgatgaggca agtcagctgt gtgtatcacc atatcgttaa ctgagtaaga
     3901 cgcttgggga tcttaactac cagtttgtta gcgtggtgag ctttttgata cgtctcggga
     3961 aaacagatct ttttgtccat tttctatgcg aggcatttta aggtagggaa ttgtagaaaa
     4021 aagaattaag ctaggttggt aattgttgtt ttgtctggac ctggttgttt tggatatgct
     4081 tattgtgata tgattaatat actggatctg gtaatagctg tatcaggagg tgtgtttgta
     4141 tggttgagta ttgggacatt tatacgatga atcgtcttaa gactggtaga ctcatggagc
     4201 gtggagctgc ttttgtagag ggtgcttatc atttagtggt tcacgcctgt gtctttaatg
     4261 acaagggaga aatgctgatt cagcagcggc aaaaggataa agagggttgg cccagctatt
     4321 gggatataac ggtaggcggc agcgctcttg caggtgagac gtcacaagag gcagtgatga
     4381 gagaactgaa ggaggagcta ggacttactc ttgatttagc tggtgtaagg cctcattttt
     4441 caattacctt tgataatggc tttgacgata cttttttgat tttgcaggct gttgatgtaa
     4501 ggaagctagt tcttcagaca gaggaggtac aggctgttcg atgggctagt cgtgatgaga
     4561 ttttagccat gattgatgct ggtattttta ttccctactt taagagcaag attgatatgt
     4621 gctttgagtt agtggggcaa tatggagcga tcaagtggtc atagagactg ctgctgtctt
     4681 agctttgctt gctatgctag tagttgtcgt tttttggctg ctgatctggt gaagcctcac
     4741 gctagtaggg acaaatggtt ggctgttttg atacaaacac gctgtctatg catcattaga
     4801 tactaactgt atttatttga atttttcatg aagattgtgt atatttgata ctataatgac
     4861 atcaaataaa ggagtattat gactgcaatc attgagagag ctcctgcaaa aataaatcta
     4921 ggcttagata ttcaaggcaa gcgaccagat ggctatcatg acctatctat ggttctagtt
     4981 agtgtagatc tttgtgatta tattacagtg gatcatttag aggaggatag gattttattg
     5041 acctctaatt gccctagatt gcctattaat gagcacaatg acgtttacaa ggcggcttat
     5101 ttgctgaaag agcgatttca aatctcaaca ggtgtctcta ttttcttgga taagagggta
     5161 cctgtttgtg ctggtatggg aggtggctca agtgatgcgg ctgcagcaat cagagcattg
     5221 aatcagctgt ggcagctaaa gcttagtccc cgtcagatga ttgacattgg catgcagatt
     5281 ggtagcgatg tgccttattg tctttttgca ggctgcgccc aagtgactgg caaaggcgag
     5341 gtggttaagc caatcaatgg ccgcttgtcc tcttgggtgg ttctagtgaa gccagaattt
     5401 ggcatttcta ctagaacgat tttttgggat attgattgtg agacgatatc tcgagtgccg
     5461 attgaggatc tggtttcagc cattgaggca ggtgattatc agcgcttgct tgcaacgatg
     5521 ggaaattcct tagaggatat ttccattgct aaacggccgt ttattcaaaa ggttaaggat
     5581 aaaatgctgc agtcaggagc agacattgcc ctgatgacag gaagtggtcc aacggtattt
     5641 gccctatgtc aaacagaaaa gcaggccaat cgtgtggtga atagcctgaa aggcttttgt
     5701 aaggaagtct acaaggttag aacgctgtag atcagccttg aagttgcgtc ttttggggcg
     5761 tcatgttata attaactggt taatgaggag agggaaatca tgacaatttt agaaaaaaag
     5821 cttgataatt tggttaatcg tattttgtta aaggctgaaa atcagcatga gctgctcttt
     5881 ggggcttgtc agagtgatgt caaattaaca aatactcagg agcatatttt gatgcttttg
     5941 tcacaggaaa agctaaccaa tacagatttg gcaaaaaggc taaatatcag tcaagcagca
     6001 gtaactaaag cgattaaagg cttgatcaag caagaaatgc tagcaggaac aaaggatacc
     6061 gttgatgctc gagtaaccta ttttgaactg actgatctag caaggccaat cgctaaggag
     6121 catacacatc atcacgataa aacactagct gtttatcatc gtttgttggc acatttttct
     6181 gcggaggagc aggtgattgt tgaaaaattt atcactgctt ttgcggagga gttagaaggg
     6241 taataatgag atacatatcg gtggaaaatc tctcgttcca gtatgacagt gagcctgttt
     6301 tagagggaat cagctatcat ttggatagtg gagaatttgt cacattgact ggtgaaaatg
     6361 gtgctgccaa gtcaaccctg atcaaggcga ccttggggat tttaaagtca agggctgggc
     6421 aggtgactat agctaaacag aacattcatg ggaaaaagct gagaattgct tacttgccac
     6481 agcaggttgc cagctttaat gcaggctttc cgtcgactgt ttatgaattt gttaaatcag
     6541 gcagatatcc tagaagtggt tggtttacca gactaagtaa gcacgatgag gagcatgttc
     6601 ggacaagctt ggagtctgtt ggcatgtggg atagtcggca taagagaata gggagtctat
     6661 caggtggtca aaagcagcgt gtggttattg cgcgtatgtt tgcttctgac cccgatattt
     6721 ttgtgcttga tgagccgacc acaggaatgg atagtggaac aacagatact ttttatgagt
     6781 tgatgcacca cagcgctcat agacatggta aggctgtttt gatgattaca catgacccag
     6841 aggaggtcaa ggcttatgct gatcgcaata ttcatttgat tagaaatcaa cggcttcctt
     6901 ggcgttgctt caacattcat gatgctgagg ctgatgagag caaaggaggg tcattccatg
     6961 cttgagattt tatcttatga ttttatgcag cgtgctgtta tggctgttgt ggcgatcagt
     7021 atctttgctc cgattttggg tatctttttg attttgcgtc gtcaaagctt gttgagtgat
     7081 acgcttagcc acgtttctct ggctggtgtg gcctttggtg ttgttcttgg tgtttcgcca
     7141 accttcacaa cgattattgt ggtggtgcta gctgccatct tgctagaata tcttagggtg
     7201 gtttataagc actatatgga gatttcgaca gctatcctaa tgtccttggg gctggctatt
     7261 tccttgatta tcatgagtaa gtcaactagc tcttctagta tgagcttgga gcaatacctt
     7321 tttggctcta tcattactat tagtacggag caggttgctg ccttatttgt cattgctttg
     7381 attattttag ccttgacgat attatttatt cgtccaatgt atatcttgac cttcgatgag
     7441 gacacagcct acgtcgatgg cttgccggtg cgtgtcatgt ctgtcttgtt taatattgtg
     7501 acaggtgttg ctattgctct aacgatccca gcggcagggg cccttttggt atcaacgatt
     7561 atggttttgc cagcaagtat tgctatgcgg cttgggaaaa actttaaatc agttattttt
     7621 cttgggatta tgattggctt tacaggcatg ctgtctggta ttttcttgtc ctatttttgg
     7681 gaaacgccgg caagtgcgac cattacgatg atttttattg cgatcttcct tgtggttaac
     7741 ctgctgtcct ttatacgtca aaaataatca tccaaagcaa gattttccta gctgtctgtg
     7801 attagtaggt tagtacagcg tattttttct tgccgcggcg aatgacggtc aactgattgt
     7861 caatgcgatc tgctgtagat aagctgtaat ccagatcctg aagtcgttct ccattgaggt
     7921 agatcgcgcc attttgtaaa tcctcacgcg cctgacgttt tgatggtgaa atgcctgctg
     7981 tgactaacat atccacgata tttaggctgt cttctgcttg aacctgatag ttagggacat
     8041 tgcttaagcc ttgcttaagc tcagctgctg aaaggttttt gatagctcct gcaaaaagct
     8101 gttcggtaat attgagggct tgctggtagg ctgcctctcc atgaaccagt gtcaccacct
     8161 cacgcgcaag tgtcttttga gcaaggcgct catggcgtgc tgcgttgaac tgctcctcaa
     8221 tagcagcaat ctcatcaagt gataagaagg tgaagatctt caggaagcgt accgcatcat
     8281 cgtccataac atttaaccag aactggtaca tctcgtaagg agatgttttt ttagcgtcaa
     8341 gccaaatcgc attaccctct gacttgccga attttttacc tgttgcatct gtaatcaatg
     8401 gcactgtcat cacatgtcca gtcttgtcag cttttttgcg gagcaattcg gtacctgctg
     8461 tcatattacc ccactggtca gagccgccga tttgcagtgt cacattgtgc ttagcattta
     8521 gctcgtaaaa atcgtagcct tgcatgacct gatatgcaaa ttcggtgtag gaaattccgg
     8581 tttcgatacg ttttttcact gaatccttgc tcatcatgta attgatagtg aagtgcttgc
     8641 cgacatcacg aaggaagtca ataaagctaa tctgtgagaa ccagtcatag ttgttgacaa
     8701 gctcagcctt gttttcaccg ttgtcaaagt caagaaagca agagagttgt tctttaatct
     8761 tttggctcca atcaagaacg gtttccttgg tttgtaggat acgctcagcg tctttaaagg
     8821 acggatcacc aatcagccca gttgccccac cgacaagagc gtagggcttg tgtcctgcta
     8881 gctgcaagcg acgtgatgtc aaaatggcaa cgagatgacc aagatgcagg ctatcagctg
     8941 ttggatcata gccagtgtaa taggatactt gcccttctgt taatgctttg acaagggctt
     9001 cttcatcggt cgtctgaaag accaagccac gagctttgag ttcttcaaaa atattcatag
     9061 gctttctcca ttttctttat gatttccgaa tcattatatc aaaaatgact gtggctgtgc
     9121 aagcttaatc aaagtttggt ataatgaaga ttgaggtacg ttatggtgaa atggaaaaag
     9181 aatcaaacaa gcaaaaatca tcagcgatta gaattagttg attttggaac ggtctttttg
     9241 cgcacattaa aattcatgtc gagctttttt tatgtagctg tctttttatt tggcatgctg
     9301 ggtgctggta tggcctttgg ctatttagcc agtcaaattg actcggtaaa aattccaagt
     9361 aaggaaagtc ttgtcaagca ggttgaatca ttgaccatga tgtcacagat tacctattca
     9421 gataatagct tgatttcagg cattgatacg gatctgctta ggacaccggt tgctaatgat
     9481 gcgatttcag acaatatcaa aaaggctatt gtctcaactg aggacgacaa ctttcagcgc
     9541 cataatggca ttgtgccaaa ggcgattttt cgtgcgactc tggcctctgt tttgggcttt
     9601 ggggagtcaa gtggtggctc tacgctgaca cagcagttga ttaagcagca agtcttgggc
     9661 gatgatccga cctttaggcg aaaatcaaag gaaattatct atgcactggc cttagagcgt
     9721 tacatgtcaa aggacgatat tttatcacat tatttaaacg tgtcgccttt tggtcgtaat
     9781 aataagggac aaaacattgc aggtgtggag gaggctgcgc gtggcatttt tggagtctct
     9841 gccaaggatt tgacggttcc gcaggcggcc tttttggcag ggcttccgca aagcccgatt
     9901 gtttattcgc cgtatttgcc gacagggcag ttaaaatcag ccgatgatat ggcctatggg
     9961 attaagcgcc agcaaaatgt cctctacaat atgtatcgaa caggtgtgct gacagaaaaa
    10021 gaatatcgtg attataaggc atatcctatt agcaatgatt ttatcaaacc tgaaacagtc
    10081 actgccaata ctcatgatta cctctactat tctgtcttgg cagaggcaca aaaggccatg
    10141 tatagctatc tgattaagcg agataaggtg cctgctaaag atttaaaaaa tgatgagact
    10201 aaggctgcct atgaggagcg agccttaact gagctgcagc atggcggcta cactgtcaaa
    10261 acaacaatca ataagccaat ccatcaggtg atgcaaaaag cggcagctca gtttggtggc
    10321 ttgttagatg atggcactgg gacagtgcag atgggcaatg tcctaacgga caatgctaca
    10381 ggtgctgttt tgggctttat tggtgggaga gactatgctc aaaatcaaaa caatcatgcc
    10441 tttaatactg ttcgctctcc aggctctagc attaagccga ttattgctta tggacctgcc
    10501 attgatcagg gattaatggg aagtgctagt gtcctatcca actatccgac gacctattcc
    10561 agcggtcaaa aaatcatgca cgtcgatagt gaaggaacag caatgatgcc cctgcaggag
    10621 gcgcttaata cctcatggaa tattccagcc ttttggactc aaaagctgct gcgtgataag
    10681 ggcgttgatg ttgaaaacta tatgagtaaa atgggatatc ggattgctga ttattccatt
    10741 gaaagtctgc cacttggtgg tgggattgag acctcggtag cccagcagac caatgcttat
    10801 cagatgattg ctaataatgg tctttatcaa aagcaatata tggtggctag tatcacagct
    10861 agtgatggat ccgttgttta tcagcatgag gccaagccgg ttcgtatttt ctcagctccg
    10921 acagcaacga ttttacagga gctcttgaga gggccgattt catctggggc aacaaccact
    10981 tttaaaagcc gattagcagg gatcaaccca agccttgcag gtgctgactg gataggtaaa
    11041 acaggaacaa ccgaaaatta taccgatgtc tggctggtct tagctactcc aagggttact
    11101 ttgggtggtt gggcaggcca tgatgacaat acctcgcttg caccactgac gggatacaat
    11161 aataattcaa attatatggc ttatttggtt aatgccatca gtcaggctga tcccaatctt
    11221 tttggccttg gtcagcggtt ttcactggat cctggtgtta tcaaggcttc tgtcttgaag
    11281 gccactggtc taaagccggg tacagtgacg atcaatggcc aaaccatctc catcggtgga
    11341 gagctaacaa ccagcctttg ggctcaaaag ggacccggag caactaccta taggtttgcc
    11401 attggtggaa cagacgcaga ctatcaaaaa gcctggggag gttttagtgg tagaagaaat
    11461 tagttgtatt ttccagacaa atagtgtata atatctataa ctatttgtcg tctaatctag
    11521 ctgaaatatt gtccagctag aaagaacagc agttaaatca cactgataag gtccgattta
    11581 gctgctcttt ttgtgcctat ttttagataa aaatcaattt tgtaacaaaa atttaaagat
    11641 tctaaaaata ccacttaaga caaatattga tgttgcaatt gtttgcttga tagcaaagct
    11701 taaaaagaaa aaggagctaa aaacttggca ggacatgacg ttcaatacgg gaaacatcgt
    11761 acccgtcgta gtttttcaag aatcaaagag gttcttgatt taccaaattt gattgaaatt
    11821 caaactgatt cattccaaga tttcttagat tcaggcttga aggaagtatt tgaagatgtg
    11881 cttccaatct caaactttac agacacgatg gagcttgagt ttgttggtta cgaatttaag
    11941 gagcctaaat atacccttga agaggctcgt atccatgatg caagctattc tgcaccaatc
    12001 tttgtgacct tccgcctgat taataaggaa actggcgaaa tcaaaacaca agaggtcttt
    12061 tttggtgatt ttccgattat gactgaaatg ggaaccttta tcatcaacgg tggagagcgt
    12121 attattgttt ctcagctggt tcggtctcct ggtgtttatt tcaatgacaa ggttgataaa
    12181 aatggtaagg ttggttatgg ctcaacagtt atccctaatc gtggtgcttg gctagagcta
    12241 gaaactgact caaaggatat tgcttatact cgtattgacc gtacgcgtaa aatcccattt
    12301 acaacgctag tgcgtgcact tggtttttct ggtgatgacg aaattattga tatttttggt
    12361 gatagtgagc ttgttcgcaa taccattgaa aaggatattc ataaaaacca aagcgattca
    12421 cgtacagatg aggctcttaa ggaaatttat gaacgcttaa gaccaggtga gccaaagaca
    12481 gctgatagct cacgcagcct tttgacagct cgtttctttg atgctcgccg ttatgacttg
    12541 gcagcagttg gccgttataa gattaataaa aagctgaaca tcaagacacg tcttttgaat
    12601 caaattattg ctgaaaatct aatagatagt gagactggag agattctggt tgaggctgga
    12661 acagagatga ctcgtagtgt gattgagtca atcgaagagc agcttgatgg ggatttgaac
    12721 aagtttgtct acacaccaaa cgattatgcg gtggtgacag agcctgtgat cctacaaaaa
    12781 ttcaaggtgg tttcaccagt tgatcctgat cgtgtggtga cgatcgttgg taatgctaac
    12841 ccagatgata aggttcgtgc ccttactccg gctgatattt tggctgagat gtcttatttc
    12901 cttaaccttg ctgaaggtct tggaaaggtc gatgacattg accacttagg taatcgtcgt
    12961 atccgtgcag ttggtgaatt gcttgctaac caattccgta ttggtcttgc tcgtatggag
    13021 cgcaatgtcc gcgagcgtat gtctgtacag gataacgatg tgttgactcc acaacagatt
    13081 attaacattc gtcctgtaac ggcggctgtc aaagaattct ttggttcttc acagctatca
    13141 cagttcatgg atcagcacaa cccattgtct gagttgtcgc acaaacgtcg tttgtctgcc
    13201 ttaggacctg gtggtttgac acgtgatcgt gctggctatg aggtgcgtga cgtgcactac
    13261 actcactatg gtcgtatgtg tccgattgaa acacctgaag ggccaaatat cggtttgatt
    13321 aataacctgt cttcatttgg acatctgaac aaatacggct ttattcaaac cccttaccgt
    13381 aaggttgatc gtgtgattgg ccgagtgact aatgagattg tttggctaac tgctgatgaa
    13441 gaggatgagt ttacagtggc tcaggctaat tctaagctca atccagacgg tacctttgct
    13501 gaagagattg tcatgggacg tcaccaaggt aataaccaag agtttcctgc tagtcaggtt
    13561 gactttgttg acgtgtctcc taagcaggta gtcgctgttg cgacagcatg tattcctttc
    13621 cttgaaaacg atgactccaa ccgcgcccta atgggagcta acatgcagcg tcaggctgtg
    13681 ccattgattg atccaaaggc tccttatgtt ggtacgggta tggaatatca agcagctcat
    13741 gattcaggtg ctgcggtaat tgcccagcat aatggtaagg ttgtcttttc agatgctgaa
    13801 agagtagagg tgcgtcgtga ggacggttca cttgatgttt accacatcac aaaattccgc
    13861 cgttcaaact ctggtactgc ctacaaccaa cgaacccttg ttaaaatagg tgatattgtt
    13921 gaaaagggtg actttatcgc tgatggccct tctatggaaa aaggtgagat ggctcttggt
    13981 caaaatccaa tcgttgctta catgacctgg gaagggtaca actttgagga cgcggttatc
    14041 atgagtgagc gtcttgtgaa ggaggacgtt tatacctctg ttcacttgga ggagtttgaa
    14101 tcagaaacac gcgacacaaa gcttggacct gaggaaatca cacgtgaagt gccaaacgtt
    14161 ggtgaagaag ccctcaagga ccttgatgaa atgggtatta tccgtatcgg tgcagaggtc
    14221 aaggaaggcg atattcttgt tggtaaggta actcctaagg gtgaaaaaga cctttctgct
    14281 gaagaacgtc tcctgcatgc tatctttggt gataaatcac gtgaggttcg tgatacctcg
    14341 ttacgtgttc ctcatggtgg tgacgggatt gtacgtgatg tgaagatctt tacacgcgca
    14401 aatggtgatg agcttcaatc aggtgttaat atgctggtgc gtgtttacat tgctcaaaag
    14461 cgtaaaatca aggtcggaga taaaatggcc gggcgtcatg gtaacaaggg tgtcgtctca
    14521 cgtattgtac cggttgagga tatgccatat ctgccagacg gaacccctgt tgacatcatg
    14581 ctgaaccctc ttggggtgcc gtctcgtatg aacattggac aggttatgga gcttcaccta
    14641 ggtatggctg ctcgtaattt gggtatccat atcgcaacac cggtctttga cggagctacg
    14701 tctgaggacc tttgggaaac tgttcgtgaa gcaggtatgg atagcgatgc taagactgtt
    14761 ctttatgatg gccgtactgg tgagccgttt gataatcgtg tgtcagttgg tgtcatgtat
    14821 atgattaagc ttcaccacat ggttgatgat aagcttcacg cgcgttctgt aggaccatac
    14881 tcactggtta cccaacagcc gcttggaggt aaagctcagt ttggtggcca acgttttggt
    14941 gagatggagg tatgggctct tgaggcttat ggtgcttcaa acgttcttca ggaaatcttg
    15001 acctataagt cagacgatgt gaatggtcgc ttgaaagctt atgaggcgat taccaaaggt
    15061 aagccaattc caaagcctgg tgtaccagaa tctttccgcg ttcttgtgaa agaattgcaa
    15121 tcacttggtc ttgatatgcg tgtccttgat gaagacgata atgaagttga gcttcgtgat
    15181 cttgatgaag gcgaagacga tgacgtgatg cacgttgacg atcttgaaaa agcgcgtgaa
    15241 aagcaggctc aggaaactca agatattgct gaatcaactg aagacaacta aatcataaac
    15301 atttgtaaca gaaataatga ctagactagg gctatttgcc ctagctgcta gtaagtcatc
    15361 aaaggcagaa aggtaaaact agtggttgac gtaaatcgtt ttaaaagtat gcaaatcaca
    15421 ttagcttcac caagtaaggt ccgttcatgg tcctatggtg aagttaaaaa acctgaaaca
    15481 atcaactacc gtacattaaa accagaacgt gagggtcttt ttgacgaagt catttttgga
    15541 ccaaccaagg attgggagtg tgcgtgtggc aaatataaac gtattcgcta taagggcatt
    15601 gtctgtgacc gttgtggggt cgaggtaacg cgtgcaaagg ttcgtcgtga acgcatggga
    15661 cacattgagc tgaaggcacc tgtctcacat atctggtatt ttaagggaat cccatctcgt
    15721 atgggcttga ctcttgatat gagtcctcgt gctcttgagg aggtaatcta ttttgcggct
    15781 tatgtggtta ttgatccaaa ggacacaccg cttgagccaa aatcactatt gacagagcgt
    15841 gaatatcgtg aaaaaatcca agaatatgga catggctcat tcattgctaa aatgggggca
    15901 gaggctattc aagacctcct aaagcgtgtt gatttggtca cagaaattgc tgagctaaag
    15961 gaagaattaa aaacagcaac aggccaaaag cgtatcaagg ctgttcgtcg gttagatgtg
    16021 cttgatgcct ttcataaatc aggcaataag ccagaatgga tgatcctgaa catcttgccg
    16081 gtcattccac cagatcttcg tcctatggtg caattggacg gtggccgctt tgcagcctca
    16141 gacttgaatg acctttaccg tcgtgtcatt aaccgtaata atcgtttagc acgtttgttg
    16201 gagcttaatg cgcctggtat cattgtgcaa aatgaaaagc gtatgctgca agaggcggtt
    16261 gatgctttga ttgataatgg tcgtcgtggt cgtcctatta caggacctgg tagtcgtccg
    16321 cttaaatcct tgagccacat gcttaaagga aaacaagggc gttttcgtca aaacctgctt
    16381 gggaagcgtg ttgacttctc aggtcgttca gttattgctg tgggtccaac gctaaaaatg
    16441 taccaatgtg gtgtaccacg tgagatggct attgagcttt tcaagccatt tgtgatacgt
    16501 gagattgttg cccgcgaatt tgccggcaac gtcaaagcag ctaagcgtat ggttgagcgt
    16561 ggcgatgagc gtatctggga tattctagaa gaggttatca aggagcatcc agtcctgctt
    16621 aaccgcgcac ctacccttca cagattaggg attcaggcct ttgagccggt gcttattgat
    16681 ggtaaggctc ttcgtcttca cccgcttgtg tgtgaggcct acaatgccga ctttgacgga
    16741 gaccaaatgg ctattcacgt gccgctttca gaggaagcac aggcagaggc tcgtttgttg
    16801 atgcttgctg ctgagcatat tcttaaccct aaggacggta agccagttgt aacaccttct
    16861 caggatatgg tgctaggaaa ctactaccta acaatggaag atgctggtcg tgaaggcgaa
    16921 ggtatggtct ttaaggacaa ggacgaagcg gtaatggctt accgtaatgg ctatgttcac
    16981 cttcatagtc gtgttggtat tgctgttgac agtatgccaa gcaagctttg gaaggatagt
    17041 caaagacaca aaatcatggt gacaacggtc ggtaagatct tgtttaatga catcatgcca
    17101 gaggaccttc cttacctcca agagccaaat aatgctaact tgacagaggg cactccagat
    17161 aaatatttct tgaagccagg tcagaatatt caggaggtta ttgatagctt accgatcaat
    17221 gtgcccttca agaagaaaaa tcttggtaac atcattgcgg aaaccttcaa gcgtttccgt
    17281 acaacagaaa catcggcctt tcttgaccgc ttgaaggacc ttggctacta tcattcaacc
    17341 cttgcgggct tgacggttgg gatcgctgat attccggtta ttgacaacaa ggctgagatc
    17401 atcgaggctg ctcaccatcg tgttgaggaa attaataagg ccttccgtcg aggcttgatg
    17461 actgatgatg atcgctatgt tgcagtcaca acaacatggc gcgaggcaaa agaagccctt
    17521 gagaagcgtc tgattgaaac acaggatcct aagaacccaa tcgttatgat gatggactca
    17581 ggagcgcgtg gtaacatctc taacttctcg cagcttgccg gtatgcgtgg cttgatggct
    17641 gctcctaatg gccgtattat ggagcttcct atcctgtcta acttccgcga aggcttgtct
    17701 gttttggaaa tgttcttctc aactcatggt gctcgtaagg gtatgactga tacggctctt
    17761 aagacagctg actcaggcta tctgacacgt cgtttagttg atgttgcgca agatgtcatc
    17821 attcgtgagg acgattgtgg tacagaccga ggccttctta ttcgagctat cacagatggc
    17881 aaggaagtca ctgaaacact tgaggagcgc ttgcagggtc gatacactcg taaatcagtc
    17941 aagcaccctg aaactggtga ggtattgatt ggtgctgacc aattaatcac tgaggacatg
    18001 gctcgcaaga ttgttgatgc tggtgttgaa gaggttacca ttcgctcagt atttacctgt
    18061 gctactcgtc atggagtgtg tcgtcactgt tacggtatca acctagcgac aggtgatgcg
    18121 gttgaggttg gtgaggctgt tggtactatc gctgcccaat ctattggtga gcctggtact
    18181 cagctgacca tgcgtacctt ccacacagga ggggttgcct ctaataccga tatcacacag
    18241 ggtcttcctc gtatccaaga aatctttgaa gcgcgcaacc ctaaagggga agcagttatc
    18301 acagaggtta aggggactgt tattgagatt gaagaggacg catcaactcg tactaagaag
    18361 gtctacgttc aaggtaaaac aggcatgggt gaatatgttg tgccatttac agcgcgtatg
    18421 aaggttgagg ttggtgatga ggtcaatcgt ggagctgccc ttacagaagg gtcaatccag
    18481 cctaagcacc tccttgaggt tcgtgatacc ttgtcagttg agacctactt gcttgctgag
    18541 gttcaaaagg tttaccgcag ccaaggggta gaaatcggag acaagcacgt tgaggttatg
    18601 gttcgtcaaa tgcttcgcaa ggtacgtgtc atggatccag gtgatacaga tcttctgcca
    18661 ggaaccttaa tggatattgc agactttaca gatgccaata aggagattgt tatctctgga
    18721 ggtattcctg cgacctctcg tccagtgctt atgggaatca caaaagcctc acttgagact
    18781 aactcattcc tatcagcagc ttccttccag gaaaccactc gcgtgctgac agacgctgct
    18841 atccgaggca aaaaagacca tctattgggg cttaaggaaa atgttatcat tggtaagatc
    18901 attccagcag gtactggtat ggttcgttac cgtaacattg aaccgcaagc tatcaatgag
    18961 gttgaggtta tcgaagaagc tgaagctaca gaagagccag caattattaa ggaataagaa
    19021 ataaaaggag ctagccttag ctccttttat catgctaaaa tcattagatt aattgggctc
    19081 catgtcaact atagtaggtg actgataact aagcacgaga ggagacgaag gtcgtcttct
    19141 cttttgtcat gttcaaagca agcatagata agtttcttga aattgtcaac gtttctgaat
    19201 ccaaatgcat tgcgcttgat gtctttgatc agtttgctag tcgcttcaaa cttggcgtta
    19261 gaataagg
//
LOCUS       DARYLD010000040        18621 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYLD010000040 DARYLD010000000
VERSION     DARYLD010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18621
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..666)
                     /locus_tag="TU651_001317"
     CDS             complement(<1..666)
                     /locus_tag="TU651_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HEL0897313.1"
                     /translation="MDEIKLYENKEIRSIWDEEKEEWYFSVVDVVGVLTEQENVRGAS
                     TYWAVLKKRLKEEGNELLTICKQLKMKATDGKMRLTDVADMQGIFRIIQSIPSPKAEP
                     FKLWLAEVGKERIDEIIDPELTIDRALETYLKKGYTREWINQRLQAIQVRKELTDAWD
                     DHGIQKGKEYAILTDEITKAWSGMTTRGYKNLKGLKKENLRDNMTTLEIVLNMLAEAT
                     TTNA"
     gene            complement(762..1727)
                     /locus_tag="TU651_001318"
     CDS             complement(762..1727)
                     /locus_tag="TU651_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL0897314.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEIIEKALEIYFKEYIGQ"
     gene            complement(1720..2496)
                     /locus_tag="TU651_001319"
     CDS             complement(1720..2496)
                     /locus_tag="TU651_001319"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL0897315.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(2648..3811)
                     /locus_tag="TU651_001320"
                     /pseudo
     CDS             complement(2648..3811)
                     /locus_tag="TU651_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3813..5534)
                     /locus_tag="TU651_001321"
     CDS             complement(3813..5534)
                     /locus_tag="TU651_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897316.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            5983..7989
                     /locus_tag="TU651_001322"
     CDS             5983..7989
                     /locus_tag="TU651_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL0897317.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(8180..8590)
                     /locus_tag="TU651_001323"
     CDS             complement(8180..8590)
                     /locus_tag="TU651_001323"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL0897318.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(8722..10071)
                     /gene="gdhA"
                     /locus_tag="TU651_001324"
     CDS             complement(8722..10071)
                     /gene="gdhA"
                     /locus_tag="TU651_001324"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL0897319.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFRQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(10212..11988)
                     /locus_tag="TU651_001325"
                     /pseudo
     CDS             complement(10212..11988)
                     /locus_tag="TU651_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(11988..13733)
                     /locus_tag="TU651_001326"
     CDS             complement(11988..13733)
                     /locus_tag="TU651_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897320.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISISKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(13838..15705)
                     /locus_tag="TU651_001327"
                     /pseudo
     CDS             complement(13838..15705)
                     /locus_tag="TU651_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(15698..16909)
                     /locus_tag="TU651_001328"
     CDS             complement(15698..16909)
                     /locus_tag="TU651_001328"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL0897321.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(17009..17857)
                     /locus_tag="TU651_001329"
     CDS             complement(17009..17857)
                     /locus_tag="TU651_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0897322.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(17857..18237)
                     /locus_tag="TU651_001330"
     CDS             complement(17857..18237)
                     /locus_tag="TU651_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL0897323.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            complement(18442..>18621)
                     /locus_tag="TU651_001331"
     CDS             complement(18442..>18621)
                     /locus_tag="TU651_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HEL0897324.1"
                     /translation="ESFFGILKSEMFYGFEKSYHSLDELEQAITEYIFYYNNKRIKTK
                     LKGLSPVQYRTKSFQ"
BASE COUNT         5429 a         4331 c         3307 g         5554 t
ORIGIN      
        1 tgcgtttgtt gttgtggctt ctgcaagcat attaagaact atttcaagag tggtcatatt
       61 atcccttaga ttttcctttt tcaaaccctt cagattttta taacctcttg ttgtcattcc
      121 ggaccatgct ttggtgattt catcagtaag aattgcgtat tctttgcctt tttgtatccc
      181 atggtcatcc caagcatcag tcagttcttt tcttacctga atggcttgaa gtctttgatt
      241 tatccactca cgtgtatatc ccttctttag ataagtttct aaggctctgt caatcgtaag
      301 ttcaggatcg ataatttcat caattcgttc ttttccaacc tcagcaagcc ataacttaaa
      361 aggttctgct ttaggggatg ggatggactg gataatacgg aatattcctt gcatatctgc
      421 tacatcagtt aaacgcattt ttccatctgt tgctttcatt ttcaactgct tacaaattgt
      481 aagcagttca tttccttctt cttttaatct cttttttagt acagcccaat aggtactagc
      541 acctcttacg ttttcttgtt ctgtcaaaac tccaactaca tcgactactg aaaaatacca
      601 ctcttctttt tcttcgtccc aaatggagcg tatctcttta ttttcataca attttatttc
      661 gtccattctg acacctgcct cttttatatc ttatcctgtt aaacaggtct tttccctttt
      721 taatacctta tattatacct taaatttata attttgtctt ttcactgacc aatatattcc
      781 ttaaagtaaa tttccaatgc tttttctata atttcttcta catcttcttt cctttcatca
      841 tgaaaaaact ttttatagac actctgagat agtttgatat tctgatactt ttttaccttc
      901 gtttttttca agttcagcaa gtatgttata accatctctt gattcagatc ttcttgtctg
      961 ttcatcagat ggagtgcttt ggcatcgctt ggttttaaac ttagttccaa ttcttcgcac
     1021 ttctgataca gatattcctg tatttctttg gaaagatagg ataaatctac tgccatcgtc
     1081 aaacctattt tatcttcatc cacatctttt ttccaagact tagataattc atttaatctt
     1141 aggtaccttg caatagatgc ccctgaaaga ttatattctt ttccaagtgt ttttctgctg
     1201 tctattttat cttcctcttt actttccttt tctataattc cctgatctaa attgtttatc
     1261 tccttttgca aatcatttct cttgccctga cttgctattt tttcatatct cattttaaga
     1321 acaagggctt tttccgtcgg cagtaaatcg gagaaagaac gctgtataag gtttgtttca
     1381 attacatagg tataggcttc tttatccgtt agattttctt taacaataca aggaatactt
     1441 tttatttttg taattcttgc tgcatttact ctattgtgtc cggaaagtat ttcatagttg
     1501 ttatcttttt tcaagacgat aattggatta agaactccgt tttccttaat gctctctacc
     1561 atatcgtcta atctcttacc tgtatataaa gtaaacggat gattatgata attttcaagc
     1621 aaatcaagtt ctatattctg tatatttcct tgttccaagg catttccatc atcaagcaaa
     1681 aaatctacgg catcggtgat ttctctcttt agaagttttt tactcatagc agatctcctt
     1741 tgccagattg tcataggcaa tgtctacact actgcctttt gcatattttt ttatgctttg
     1801 cccgctatag atggcttccc caactttaac tgttttcgga attttggttt gaaagacctt
     1861 gattttcttt tggaacattt cttctacttg ctccatcagt gttttggaca gattggttct
     1921 attctcacac atggttagta aaatcccctg cactttcagt ttcggattca ctctcttttt
     1981 tattttttga acagttttta aaagttcatt gattccaaca actgcgaaca gctgtgtatc
     2041 cgctactata aggacactgt ctgaggcaca aagagcattt atagtcaaaa cactaagtga
     2101 tggtgatgta tctatgagaa tatagtcata attctctttt accctcctaa taatttccga
     2161 taatatacgt tcacttcctg tttctgctct catttgtgtt tcaacggcgg ataagaaaat
     2221 gcttgagggg ataatatcta tctcatcata agatttggta tagccctcta ccaaatagct
     2281 ttcttcttcc tccagttcta ccattaacaa atgccctatg gtttttatat tttctgtatt
     2341 tcccatatca aaacatcttg taagattagc ttgtggatca aggtcaatga ctaatacttt
     2401 tttccccagt tcttttagtg aataggcaag gtttagagtt gtagttgttt ttccaactcc
     2461 gccttttcga ttggctatgg ttatcacttc tgccataaag tccctccttc ttctctatac
     2521 agagatttca ttttatgcta tacttttata taattttaga tataaaaaaa gatgatagcc
     2581 tcaatccatc atcaagttta aaagttttgc ggaagccttt aaccattgat tttacttgga
     2641 tttattgtac tatcatcatt atagcattgt ccccagagcc agtatgccct actagggcaa
     2701 ccgtctcccc tttatcagca tgaatggtaa tatcagataa aactgtcttg ccattttcgt
     2761 aagcaaaata caccttggta aaatccacag taccatctgt tagctcaatt gctcgtgctt
     2821 tatccggctc tgtctgcgcc tcaagcagct tcattaggcg cgttcctgtc gctgttgagc
     2881 gctgaatatt aggtagctgc ctaaccagca tacttaataa atcaaacaag cgcagcaaat
     2941 aattgacgta aataaagagc ttaccaactg tgatgcctga tctcccctgc aagaactggt
     3001 aaccaataac agccaaaata gcggcaatca tgccatactt taccaattcc gtcagggtcc
     3061 atgaagcaac tgactctgca aaaataatcc tatcatcagc tgttttcatc tggtggatct
     3121 gctcttcaaa ttcctctaag atcgtatcct cttgatgata aagctgaata atagaaacac
     3181 cattcatggt ttcgttgact tgtgtgttga cagcgctcct agcctgataa aaatccttca
     3241 ttggctggtc agtcaagctt ttatacagcc attgcatgcc ataaaagagt ggcataataa
     3301 gcagcaacag caagcctgac ttcacatcaa ggtaaatcat caccacataa ataaaaataa
     3361 tttgtgaaag actgacaata atttgagaca aaaggttatc ataaaattga ttcttcaggg
     3421 tttcagtatc attaacaatc ctagttgcaa tctttcctgc aggctgatga tcaaaataag
     3481 ctatcggcag cctctgcatg acatcaaagg ctcgattacg aagattagca acgatcctat
     3541 tagaggaata aaccagcatt cgataagaga tataacgcaa aactgctgtt atcacaatta
     3601 acagcaaata cagcaggagc aagcgctgaa agccttcaat cggtacctct tttcctctag
     3661 ctatcggagt caagtaatga tcaatcgttt gttgcaacaa taagggagcc atctgacctc
     3721 cagctgttgc cactagcaaa aagcctattg ccagggaaaa agccaaggtc acagctttaa
     3781 tttcttttat taattttata aatagggtca tcttaaacct cctgagcctg ctgacgctgg
     3841 tactgttcat aataccagcc cttctgagct aaaagttgtt ggggctgacc ttcctctact
     3901 atctgcccct gatccagaac aataacccaa tcggcatgct gaatcgcaga caagcgatgg
     3961 ctaacaataa gtgttgtctt tccctttctt tcgtcttgaa tgtgtcgaat aatatcagtc
     4021 tctgttctag catcaactgc cgacagggaa tcatctaaaa tcagcaaatc tggctgggac
     4081 aaaaaggctc tggcaatcga aatacgctgc ttttgacctc ctgaaataga cagaccacgc
     4141 tctccaatct cagtatccaa gccctttgcc attccttgaa catcacgcgt aaaggccgca
     4201 gtttcaatcg cctccaagat ttcctcagtt gtagctgcct ttttccccat cgcaatgttt
     4261 tgagcaaccg tttttgaaaa caggatatgc tcctgtggca catagccaat ttgacgctca
     4321 agtgattgac gcttataatc caagacacta cgatgattaa tcatcagctg cccctgccca
     4381 agagggtatt gtctcaaaaa ctgcctgaca agggttgttt taccagagcc tgttttacca
     4441 acaatcccta aggtttgtcc ctttttcagg gttaaattga tcttttctaa gctaggccta
     4501 gaactattgg cataggtaaa gctatagtct ataaaagcaa tctgatcaaa gctctctaac
     4561 tcaagctggc catcaggctc catatcatca cttgtttcga tgagttcatt aatcttacca
     4621 aaagaggtct ttcctgtctg ataaaccaaa ataaagtctg acagcatgcc aaagggctcc
     4681 accaaagaca ccagataaag ctgcagcgca atgacttgac caagtgttac ctctgagctt
     4741 gctatgagct gtaggcctac cattaaaatg attactgtac taatggcaat catgacgctg
     4801 taaagaggaa agtacaaggc acgatacttg gccacctgat tccatttatc tgccaaattc
     4861 tgagtctttt gagcaaaatg aagtgccaaa taatcttttt tactgtaagc acgcatcact
     4921 ctaatgccct caacggtttc tagtacctca tcactaaggc ttgaaatcgc ctcacgcgcc
     4981 tcttcaacca aatgctcttg ctttttcgtc acaccataga tcatcaccat cataagcaaa
     5041 atcggtacta ttcctatcaa ggtcattttc caagaaatca aaaacatggt cggaataata
     5101 aaagcaatca taccaccagc atataggata atcatcaagc catagccgat aaggtccata
     5161 agtgcttcga catctgttga aaaacgcgtg atcatgtcac ctgagcgaaa tttctcataa
     5221 aaaggcgttc tcataaaaac aagctttcga aaggcacgct gctgaatatc aaacttaaaa
     5281 tgaactgcct cctgaaataa atgaagatgc cacaaataag caaccccata agacactact
     5341 gccgtagcca aaagaatgat aacatgcctc accaatgccc ctgagcttag ctgatgcctt
     5401 gacatcaaat caaccaagtc ttgaataacc cttgttggta tcacaagtga ggcatcatat
     5461 atcactaaag tcattgcaat aaggatataa atccatttct tttgcttaat atgttgaaca
     5521 attaaggtca gcatcatatc ctccatttct gaactaacct atttcaagct gtcttaaaat
     5581 aggatttttg cacacaaaaa gcccgcaata agatatcctt cctaccgcgg gctctactat
     5641 ttctatttag tgaaactaaa agaaactaac tgttttggtt agaaaggaga ctatcgtaat
     5701 aatggttaaa tagttgaatg aaacggatca ttattaattt ctcctttctt ttaatctgcc
     5761 taacatctta tcatagaata ctgggcttgt aaagcctttt ttggatagtt cttctatttt
     5821 tttacaaaaa acgcttccaa tgtttgcatt ttaaacgttt tcagtgatta gcaaacgcta
     5881 tcgttgaatt tttgttagct tttttattaa tttttgttga attctcattt aaataatagt
     5941 acacttaact tgtgacaata ctttaaactt ttaggagcgt ttatgaaaaa gcattttgtt
     6001 ttaaaaagta gtgttcttgg tgtctttgcc ggagtttcta tgctagtaac cggcgtgcag
     6061 gccgatcagg tagacgtgca atttcttggt gtcaatgact ttcatggtgc cttagacaca
     6121 accggctctg cctacatgcc agaaggaaag gtatctaacg ctggtaccgc agcacaatta
     6181 gctgcttatc tggacgatgc agaggctgac tttaagcaaa caagcccaga tgggacaagc
     6241 attcgtgttc aaccaggaga tatggtcgga gctagtcctg ctaattctgg actattacag
     6301 gacgagccaa cggttaaggt attcaaccag atgggctttg aatacggaac ccttgggaat
     6361 cacgaattcg atgagggctt agctgaattc aaccgtatca tgacaggcac tgcacctgct
     6421 gaagactcag ctatcaacga cattactaag caatacgagc atgaagcttc aaatcaaacc
     6481 cttgtcattg caaatgtcgt tgacaaggag accaacacga ttccttttgg ctggaagcct
     6541 tatgctgtca aagaagtccc agttaatgat aagtcagtca aggtgggctt tatcggtgtt
     6601 gtgacaacag aaattccaaa ccttgtccta aaacaaaatt atgaacaata tgattaccta
     6661 gactctgcag aaaccatcgt taaatatgct aaagagctcc aagagcagca ggtcaatgcg
     6721 attgttgtcc tagctcatat cccagcaaca agtgataacg gggtagttca tgatgagatg
     6781 gcagcagtta tggaaaaggt taaccagctt tatcctgagc atagtgtgga tattgtcttt
     6841 gctggtcaca accaccaata caccaacggt accattggca caacacgtgt cgttcaggct
     6901 gtttcacagg ggaaagccta tgcagatgtt cgtggaacac tagacactga cctcaatgat
     6961 tttgtagcca ctcctgaagc aaaggtcatt gccgttgctc ctggcataaa aacaggcaat
     7021 gccgacattc aagccattgt tgatcaagcc aatgacattg tcaaaaccgt taccgagcta
     7081 aagatcggta cagcagctac ctcttcaacg atttctaaaa cagaaaacga agacaaggaa
     7141 tctcctgttg gcaatttgat aacaactgcc caattaacca ttggtagaaa aaccttccct
     7201 catgttgatt ttgccatgac aaataatggc ggtattcgcg ctgacttggt ggtcaaagag
     7261 gatcaaacca ttacctgggg agctgcacag gctgttcaac catttggcaa tattcttcag
     7321 gtcgttcaaa tgactggcca acaaatctat gatgtcttga accaacaata cgatgaagac
     7381 caaaaatact tccttcaaat gtctggactc aaatacactt atacagctaa tgaggctaac
     7441 gatccttcaa caccgtttaa ggtagtaaag gcttataaag ataatggtga agaaattgat
     7501 ccagcagctc aatacaccct aatcatcaac gacttcctat atggcggtgg tgatggcttc
     7561 tccgtcttta aggacgctaa gctactagga gccattaatc ctgatactga ggtctttatc
     7621 gaatacatca aggaccttga agcagctgga aagactgtaa gtgctggtat taacggtgtg
     7681 aaaacctatg tcactgccag tcttgaaggc tctactcaaa gtgatcatac cggcaagcac
     7741 gagatcatca accgcgtctt taagaatcgt gagggcaagg tgcttgctac tgagcttgtc
     7801 tctgacctat ttacgcctgc tcaaaatgct aatcctgcca caagcatcaa gcctctagca
     7861 gctaaaaagc aagctaatgc tgccttacca gcaacaggaa caagccagca ttctgctgct
     7921 gccatgacaa tcctaggact actaacctta actggtacta gccttttcaa gaaaaaggaa
     7981 ggccaataaa atcgtcctag ccataacagc aataaccgac tgtatcttaa gcatacagcc
     8041 ggttttctga tttatgtgac gtttatttgt ttcgcacctg ttgagcaaga caaataaacc
     8101 acccatctat ggactgccct cattcgttag attttctgtc taacttttgg ggtgcagttc
     8161 actaacgggt ggtcatgatt taaatcaata tgccctccag atgatccagc tcatgctggc
     8221 agatttgtgc aggcaggcct gtcaatctca gggatttctt gtgccaatgt gcatcaaggt
     8281 aatcaacctt gatctcctga taacgctttg tcttacgttg gccgattagt gataggcagg
     8341 attcctctgc ctcaaacgct tcacgcttag caattaatac aggattaaac atcaccaaat
     8401 ccacaaagcc catgctaata ataataaccc tcttgttttc ccctatcata ttagcagcca
     8461 gccccaggca gctatcacga taataagcta aggtatcctg caggtcttga ccaatccaaa
     8521 ggtccttttt cgttgctggc tgtgcttttt gctgcaagaa aaaggtgtcc ttcacgattt
     8581 ttttgatcat cagcttctcc ttgattcatt gctctaatcg gcatgcattg tctagatgac
     8641 cgatcgtata tcttaacgtc attgagctaa gattaatgtg ctaaccctac tgatatattc
     8701 agcatatacc agccacagct cttaaacgat tccctgtgct gacatggcct gagcaacttt
     8761 gagaaagcct gcaatattag ctcccaccac taggttgcct tcttgaccac attccttggc
     8821 ggcagcggct gctttttgat aaatagcctt catgatgtca tacaatcgat gatccacctc
     8881 ttcaaaggtc catgcggtac gtccgctatt ttgtgccatt tccagcgcag aaactgctac
     8941 accgccagca tttgctgctt tagcaggtcc aaaaagaacc ccagcctgct gaaattgctc
     9001 aatagcctct aaggttgagg gcatgttagc cccttcgaca acagctttaa ccccatgctc
     9061 aatcaaggct ttagcatctg cctcttgtag ctcattttga gtcgcacatg gaaaggcaag
     9121 gtctgcctta atagtccaga tggatccctc accagccggt gtaaacacag cagccgggtg
     9181 actctctaga taggtcttga tacgctcacg cttcacttcc ttgatttgct ttagggtctc
     9241 aagatcaatg cccttatcat cataaacgta accagaggaa tccgacactg ctaatacctt
     9301 aacacctaag gcctgcaatt tttccgttgc gtaaatggca acatttcctg atccagatac
     9361 aatagctgtt ttaccagcca agtcctgccc cttagccgcc agcatttgct gagcaaaata
     9421 aaccacacca tagcctgtgg cctctgtgcg agccaaagag ccaccataag ctaagccttt
     9481 tcctgtcaac acaccattct taaagccatt aagacgctta tattgcctaa ataaatagcc
     9541 aatttcgcga gcccctacac caatatcacc agcaggaaca tcaaggtcag gtccaatatg
     9601 cctttgcagc tctgtcataa agctttgtgt gaagcgcatg atttctaggt ctgatttgcc
     9661 tttaggatca aaatttgatc ctccttttcc tcctccaata ggctgaccag tcagagcatt
     9721 tttgaaaatc tgctcaaagc caagaaattt aactatagac tggttaacag aagggtgaaa
     9781 gcgaagccct cccttatatg gaccgatagc tgatgaaaat tgcacgcggt agccacgatt
     9841 aacttggacc ctgccctggt catcaaccca aggcacccta aaggaaatca cacgctcagg
     9901 ctcaaccaag cgctctaata gattttcctc aatataatta gggtattttt caaaaacagg
     9961 aatcaaggaa tcaaatacct ccttgaccgc ctgaagaaat tcagtctcat gcggattatc
    10021 ccttttgacc ttatcaaaaa cactggctac atagtctttt gctgatacca ttatatatcc
    10081 tctcgcttct tcattctatt ttaagtatag tcaatattat aaattttctg aattttgatg
    10141 tcaagctttt actatgatct aaagcaaatt aaaagagcct tggaacgatt cattccaaga
    10201 ccctaagctt tttaagactg actggtctta aattggctat gataaagctc ataatagaag
    10261 cccttagcag ctaataggct gtcatgattc ccctgctcga taatctgacc atcttttaga
    10321 actaaaatct tatccgcctc ttgaatggtt gataagcggt gagcaataac aaagctagtc
    10381 ctgccaacca ttaatcgctt catcgccttt tgaatcaaaa gctctaaacg tgtatcaaca
    10441 gacgaggtgg cctcatctag gattagcagc tttggatctg ctaagagagc tcgagcaatg
    10501 gtcagcagct gcttttgccc cagggaaata ttgctagatt cctgattcat caccatatga
    10561 tagccacctg gcaatgtcct aatgaaatga tcaacattgg cagccttagc agcctcaatt
    10621 atttgttcat cagtcgcctc taaatgacca aagcgcaagt tttcctgaat gctgccctca
    10681 aagagccaag cgtcctgcag caccatacca aactgacgcc tataggcttg acgtgacaac
    10741 tgacgaatgt cctgaccatc aactgtgata gagccctcat tcacatcata aaaccgcatt
    10801 aataaattaa tcagggtggt cttgccggct cctgtcggac caacgatagc taccatctca
    10861 ccaggcttaa cctctaaatt gaaatttcta atcagaggat tgtctgctgt atagctaaaa
    10921 tcaacctgat taaaggacac ctgacctgtt aaatcatgtt ctaaatgctc ttgggcaata
    10981 gtcaattcat ctgcctcatc aagcactgca aagatacgtt ctaaggatga cttggcactt
    11041 tgcagtggac cagccagctg tgttatggtc tgaataggct gactgatttg ccaaatgtac
    11101 tgaacaaagg cttgcatgtt tgttcccgat tgtcaggcgg cctgctatca cctgtaagcc
    11161 agcgattaag gcaacaatca tgtaaacaga atctgaaata aaatgcagaa ctggcatcat
    11221 gatcccagaa ataaagctgg ccttaaagcc tacttcttgt aatcgctcag tgatctggtg
    11281 aaattcctcc tttgaggctt cttcacgacc atacagtttt aaaatattaa agccggtcaa
    11341 attttcctgc acaaagccat tcatttctcc caaaatatta gcctgcgctt taaaataagg
    11401 ctgtgatttt tttaaaacaa atcgagaagc agcatatatc aacgggatag cgataatcac
    11461 aacagaggct aggggggcat taatatacaa gaccatgcca accaccaaaa taagggtaaa
    11521 aaaggcgtta acaatctgta aaaaggactg ctgtaaggca ttagagactg tctcaacatc
    11581 agaggtaaac cggcctagca tatcgccgaa ctgatgctta tcaaaataag acacagggat
    11641 acgattaatt ttttgactga ggtctcgacg aagatcacaa atgcttgatt gcacagccct
    11701 tgtcataaaa tagtttgaac cataagagcc taactcgtaa acaagggccc taatgatata
    11761 gagagctaaa agaaaggcga tataggtttt attaatgcct gcaccagaga ctccctttgc
    11821 tatgtctaat aggtttgcag atagctctgt tatcaccaag ccaagaacaa agggctctaa
    11881 gacactcatc acagcactga ctatttttaa aataatggca gttattagtg agagcctata
    11941 ggcactaagg taggtccaaa ttcttctaaa cacatgcttt tcagtcatta atccccctcc
    12001 tcttttgtca tgtcttcctt gtttagctga gaattggcaa tttcacgata gatggcattg
    12061 cttgtaagca attcctcatg tgtacctcgg ccaacaattt ctccctgatc caagacaatg
    12121 atttgatcag catccataat cgtgcccacc ctttgagcca caattaagac cgttgcatct
    12181 tgtgtcacct ctttcagccg tctgcgtaat tcagcatctg tcttgtaatc tagggcagaa
    12241 aaggaatcgt caaagatata gatgtctggc tgcttgacca ctgctctggc aatagacagg
    12301 cgctgctttt gccctcctga tagattactg ccggcctcag ctagatgggt ttgatagccc
    12361 ttttcacgac tggtaataaa gtccttcgct tgggaaacct ctgttgcctg ctcaagctca
    12421 ctgtggctgg catctgactt accatatttt aggttttcct caatggttcc tgtaaatagc
    12481 agggcttttt gaggaataaa gccgatttta gaacgcagcg cttttaattg ataatccctg
    12541 acatcaatgc catcaaccaa gattctccct aaggtcacgt cataaaatcg tgggatcaga
    12601 ttaaccaaag atgattttcc tgaacctgtc gagccgataa aagcaatggt ctctccaggc
    12661 ctagtcttaa atgagatgtt atgtaaaact ggactttccg tttcacccgg ataggcaaag
    12721 gtcacgttat caaattctag ataaccacgt gttgtgaacg ctgttatacc atcttcattt
    12781 ttagaaatcg aaatcggcat atccagcact tccttgatac gcttgcttga cactgctgtt
    12841 ttagggtaca tggtaaagag gttggcaaac attaaaaatg aaaaaagagc atgaaagcta
    12901 tattcgataa aggccaccaa atcaccaatc ttaaactgcc cccttgccaa gggatccaag
    12961 gcaaaccaga cgatccccac aatcatagca atgataattt gcacaaataa gggctctgtt
    13021 aagcctgtca aggtaaatag tcgctttgag attccagaat agtgatcatt gcgcttattg
    13081 aagcgctctt cttgaaagtc ttctcttgca aaggctcgaa taactctcag acctgtcagg
    13141 ttttcacgca ccaattggtt aatacgatca aggctctcct gctgcttttc tgataagggt
    13201 cttgtcttta tcgcaacata aagcaccaca ataactaaaa aaggcatggc aacagccaca
    13261 atccaagcca atgatggact ggttaaaaag atcatcacca ctgaaaagat catcatcaaa
    13321 ggagttacga cacccagcct caaggacatt tcagcaaatt gcatcaaaac aaaggcatca
    13381 tttgttatcc gagtaaccag ggaggctatg ccaatttttt catattccga atgcgaataa
    13441 tcctgcaagc agctatacat gtcattacgt aaatccttga tcatgttggt ggttagctta
    13501 cccgaagcat aggataaaat cacccgtcca atgacaccta aaagtacgat aataaacatc
    13561 atcagagccc aaaaataaag agccctttga tcctgctgca taacgccttg atcaatcata
    13621 cgagccaata ttgttggtag ccccagattg accagaacaa ataacaagcc acccacaata
    13681 tcgaaacaaa tccatttagg tcttgttttt aaataggacc aaattaaagc cattcatttc
    13741 ctcccaaata atagtgatat gaaaagaagc gcaagctagc acttcttttt gtctataact
    13801 agtttaacac aaaaatatga aattgacaca taattaatta ttcttctaat tcgcttaggt
    13861 aatcaaagcg ctcataggct tcaagcagct caagattccg ctgatccagc tccttttgat
    13921 attgtgccaa ttggtcgtaa tcacttgccg ctctgagcat ttgctcctca atagtagcta
    13981 tttgttgctc gatagcagct agcttttctt caatagctgc ccattccttt ttctcaagat
    14041 aggacattct ctttttagag gtgacctgat ggtcagtgcc agctttttgc tcactgacag
    14101 caggctctat gacctctgct tcaaaagcct tttcatctaa atagtcgcta tagttaccat
    14161 agtattctct gatagctcca tgctcaaaag ccaatacttt tgttgcaacc ttatccaaga
    14221 aataccgatc atgactcact gtaatgaccg gaccagcaaa ttgagctaaa aaatgctcca
    14281 acactgtcaa ggttgcaata tccaaatcat tggtcggctc atccagcagc aggacgttgg
    14341 gcttttcgat caagagcttt agcaaataca gtcttttttc tccccgcctg atagcttagc
    14401 gattaaggag ccatgactag aacgcggaaa aagaaattgc tccaaaagct cactgatgct
    14461 agtggtgcca acactggtct tgacctcatc tgccacctcc tgcaaatagc taatcacgcg
    14521 cttgctgccg tccatatcct tgatttgctg tgaaaaataa ccaatacgga tcgtctcgcc
    14581 aatctctagc tgaccagctg ttggttttaa gtcaccagtc atcaagctaa gcagggtggt
    14641 ctttccagca ccgttagctc caacaatgcc gatacggtcc ttattttgaa tgatcaggtt
    14701 aaaatgctca ataatggcct gatcaccata agcaaaggaa acctccttga aattaatgac
    14761 cttcttgcca atacgactgg cttcaaaggc catatctaat tgatctatag gcctttcctg
    14821 atgaaggtcc ttttttaact gttcaaagcg gttaattctg gcctgctgct tggtcgcacg
    14881 cgcctgtggc tgtgtcctca tccaagccag ctcctgttta tagagctgct ttttcttatg
    14941 caaatgagct gcttcgcgct cgtcttgctc agccttcaga cgcacataat cctggtaatt
    15001 gccctgatat tcagtcacat gagccttatc caattcaaag atacgtgtgg ctatactatc
    15061 caaaaaatag cgatcatgtg taataaatag aacagtcctt ttagaggtcc ttaagtaatg
    15121 acttaaccaa gcgatggtat caatatccaa atgattggtc ggctcatcta gcagcaacaa
    15181 atcactggct ccaagcaaga cctgagccag ctgtacccga cgtctcatac caccggacag
    15241 gtcacccact ctctgatcca gattgacaat accaagcttt gataagaccg tcttaacctc
    15301 actttcgatc gaccaaacat ctaatcgatc catctcagtc atcacctctg ctagcttttc
    15361 ctgattgcta tctgaatagt cagccatcaa cagctcatat tggcgaatca gctgcatttc
    15421 ctttaattct agggacagaa cagtatctaa aacagactga tcatcatcaa agtccggctc
    15481 ctgtgttaaa taagatatac gatagtcatt tgcctttgaa aaaggtgagc ggtcaccatc
    15541 aaagcccact ttttcagaaa taacatcaag caaggttgtt tttcctgtcc cattgacacc
    15601 aataatgcca atgcgatcac cagcatgaat aataaaggaa atatcctgaa aaacggtctt
    15661 atctccaaca gacttcgtca gatgttcaac gataaaatca ctcatttagt agttcccttc
    15721 taacaaaagc ctcaatgtgt tctctttgat tgacgagacg cccctctaca atggcctgct
    15781 caatctgatt taaaagcatt cccagctgtg gtcctggctt cattccaagc tcacgaatca
    15841 gataagagcc attgaccaca atatcatgct tatcatggat cgtcagctcc tgatacaagc
    15901 tctcaacacg cttggcctca ctgaccaagc cctgtgcctg tcgtaaatcg tcaacgagta
    15961 aagccaagtc cttgccaaac gagtaaatat cccatttttc tagctgtctt tcttggcgaa
    16021 tctgataaag agaggccatc atcgtaaccc tacgctgaaa atcattagag gttttccaag
    16081 cctttaaaaa ggctttaggc tgatcaagct ccagcataac cagcaaatag gcccaagcct
    16141 gatgattgtc ctgaaacaca taatccgctg ctaaggtttt caggtacttt tgcagggctt
    16201 cttccttgcc cactaagcct ggcaaatagt taaaggcctg acatgccacc atagctaaga
    16261 tacctttacg ccattttggg gccattaaaa gcttatcaag ctcaataaaa gagcgctcaa
    16321 tagaaatctt ctccagcaag ggagcatggc ttttcattgc ttcaaaggtc tcagcctcaa
    16381 tatcaaaatc taagctggca gcaaaccgaa agcctcgcat aatccgcagg gcatcctcct
    16441 caaagcgctc ctgaggcctt ccaacagctc ttagaagctt atgctttagg tcctctaagc
    16501 cattaaagat atcaataacc tgtccgtcct catctaaggc aagagcattg acagtaaaat
    16561 cccttcgttt taaatcctct tccaaggacc gaacaaagga tacctgacta gggcgcctat
    16621 aatccacata aacgtcctca gttcgaaacg ttgtgatctc atattcactg ccattttcta
    16681 aaacaagcac tgtgccatgc tcaatcccaa catcaattgt tcttaagaaa atagcctttg
    16741 tctcctctgg atagcagcta gcagctatat caacatcatg aataggcctg tttaataagc
    16801 tatccctcac acttccacca acaaaatagg cctcaaagcc agcctgcttg atttttttca
    16861 ctattggtaa agccttctga aattcagaag gcattgtcat taatgttatc atgttttaat
    16921 ctaccaccta aaagctccta gagccttgtc atatgcttcc cgttaaaggc tgtcatatca
    16981 agctcagatt ggtcatgggc aagcctcttt agacaagagg cgttatgcca aaggcaacag
    17041 ctccttctcc aagatgggct gcaatcactg caccaaaatg aacctcctca acagggcagg
    17101 tatagccatt atccaacaag agctgcttta agatatcagc cttatcctgc gctctagcat
    17161 ggataattga tacctcgtac tgaccactag ctgtcaattc ctttaagata tcaaccaagc
    17221 gcttcatggc ctttttttcc gttctaacct tttcatagac gacaatcttt ccttcactat
    17281 caaagcgaag aattggcttg atgctgagca aatttcccag caaagcagaa ccgtttgata
    17341 agcgtcctcc cttgaccaaa tgattcaaat catcaaccat gataaaggct gtggttccag
    17401 cgatttgctc ttctagctta tccataatct ctgcaaagct caagccttgc tgagaccact
    17461 ctaaagcatt tctaaccatg ctgcctaatg gtgctgaggt gattttacta tctggaaaag
    17521 caatggtcaa ctcagggtgc tcctcgatga gaaattgaat attttgccaa aatcctgaaa
    17581 taccactagc caagaacaag ccaatcacat gagtatagtg ctcagttgac agacgcccta
    17641 gtaaatcatc taattcagag aggctgggct gactggtttt tggcagctct tgagattctc
    17701 tcatgctttg gtaaaaggct tcaatggtca ggttttgtcc ttcgacatag ctttgaccat
    17761 ctatgattac aggtatgtct aatacaaaaa tatcggcatg ctccgctaac tgctctggaa
    17821 ggtgagctgt attatcagtt attattgcta acttcattaa cttttaaact ccaaattaat
    17881 accaggacga tccaaggcaa tttctgtcac ttcgtaggtc aagcgcttca ccatgtctaa
    17941 taatggagca gccaaggatt cgacctcctc ttgtgtaaat tcactaggct tatccaccaa
    18001 gcgtcctaaa atacgaacca tctgtgaaat cacaccacta atcacaaact cttccttgac
    18061 aatgacaaat tgtaaaacag aaacaatagc cgtctcttta ttttccacat ctttattaat
    18121 caactgaaag gttacttcaa agtttgtttc cggtgttcca ttttcttttt cccattctaa
    18181 atttctggcg tcataatggt actgattgac aaattctttt tcacgtacta attgcatgat
    18241 ttcgttctcc ttaatggcga tatgacccat tatagcatag atttgacgaa tattaaagta
    18301 gacttaaacc agtattttgg ataatttttt tccagacctt gtcacttcaa taaatataaa
    18361 cctgccttct atcaaccaat caatctccta caacaaaaaa acaccccaag gtgtactgcc
    18421 cccaaaaagt tgaacgaata attattgaaa ggatttagtt ctgtattgaa cagggctaag
    18481 tccttttagt ttagttttga ttcgtttatt gttgtagtaa aagatgtatt cagtgattgc
    18541 ttgttcgagc tcatccagtg agtggtagga tttctcaaag ccatagaaca tctctgactt
    18601 taaaatgcca aagaaggatt c
//
LOCUS       DARYLD010000041        18235 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYLD010000041 DARYLD010000000
VERSION     DARYLD010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18235
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            341..1033
                     /gene="pyrF"
                     /locus_tag="TU651_001332"
     CDS             341..1033
                     /gene="pyrF"
                     /locus_tag="TU651_001332"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL0897325.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            1093..1728
                     /locus_tag="TU651_001333"
     CDS             1093..1728
                     /locus_tag="TU651_001333"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL0897326.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            1780..2523
                     /locus_tag="TU651_001334"
     CDS             1780..2523
                     /locus_tag="TU651_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0897327.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            2758..4212
                     /locus_tag="TU651_001335"
     CDS             2758..4212
                     /locus_tag="TU651_001335"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL0897328.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            4332..5198
                     /locus_tag="TU651_001336"
     CDS             4332..5198
                     /locus_tag="TU651_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL0897329.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            5226..5879
                     /locus_tag="TU651_001337"
     CDS             5226..5879
                     /locus_tag="TU651_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL0897330.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            6010..6417
                     /locus_tag="TU651_001338"
     CDS             6010..6417
                     /locus_tag="TU651_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0897331.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            6429..7082
                     /locus_tag="TU651_001339"
     CDS             6429..7082
                     /locus_tag="TU651_001339"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL0897332.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            7314..8588
                     /locus_tag="TU651_001340"
     CDS             7314..8588
                     /locus_tag="TU651_001340"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL0897333.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(8642..9289)
                     /gene="plsY"
                     /locus_tag="TU651_001341"
     CDS             complement(8642..9289)
                     /gene="plsY"
                     /locus_tag="TU651_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL0897334.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            9422..11371
                     /gene="parE"
                     /locus_tag="TU651_001342"
     CDS             9422..11371
                     /gene="parE"
                     /locus_tag="TU651_001342"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL0897335.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            11473..12288
                     /locus_tag="TU651_001343"
     CDS             11473..12288
                     /locus_tag="TU651_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL0897336.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            12763..15222
                     /gene="parC"
                     /locus_tag="TU651_001344"
     CDS             12763..15222
                     /gene="parC"
                     /locus_tag="TU651_001344"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL0897337.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            15320..16345
                     /locus_tag="TU651_001345"
     CDS             15320..16345
                     /locus_tag="TU651_001345"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL0897338.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            16413..16643
                     /locus_tag="TU651_001346"
     CDS             16413..16643
                     /locus_tag="TU651_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL0897339.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            16704..16784
                     /locus_tag="TU651_001347"
     tRNA            16704..16784
                     /locus_tag="TU651_001347"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16738..16740,aa:Tyr,seq:gta)
     gene            16823..16894
                     /locus_tag="TU651_001348"
     tRNA            16823..16894
                     /locus_tag="TU651_001348"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16855..16857,aa:Gln,seq:ttg)
     gene            17022..18224
                     /gene="rpsA"
                     /locus_tag="TU651_001349"
     CDS             17022..18224
                     /gene="rpsA"
                     /locus_tag="TU651_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL0897340.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         5247 a         3511 c         4427 g         5050 t
ORIGIN      
        1 taacgtacag caagctttat tttcttgcta aaaatctttt ttataccttt gtcgtgtgag
       61 taatgtcaaa accctttgac aagggctgtc aaaaaagcta taatgattga gataagttac
      121 ctttaagtga gtccagagag gcgagcaagg tacacaggat aagatgagag ggtttgctct
      181 cttgattttc gtgtagcctc gcttctttgg aagtgaggct tttatggtgt gactttcagt
      241 tggtctcgtg gtaatgattc ataagaccaa taaaccgctc gttagacggg tgggcatgat
      301 ttgtttggga gtaccccaag ctgcatagaa aggataggtt atgcgagaag aacgccctat
      361 tattgcctta gattttcctt cctttgagga ggtcaagtca tttctgtcgc tgtttccagc
      421 tgatgagagg ctatacgtta agattggtat ggaactgtat tatgctgaag gaccagatat
      481 tgtccgttat gtcaagtcct taggtcacag tgtttttctg gatttgaagc tgcatgatat
      541 tccaaataca gtcaaatcaa cgatggcagt cctatcaagg cttggtatag acatgacgac
      601 tgtgcaggct gctggaggtg tagagatgct tagagcagcg cgtgagggct tggggcaggg
      661 tccgattctc attgcggtga cacagctaac atcaactagc gaagagcaaa tgcgtgagga
      721 tcaaaacatt caatccacgc tgttagcatc tgtgcttcac tatgccaagc gtaccgctca
      781 ggctaagcta gatggcgtgg tttgctcagc ccatgaggtc aaggccatta agtcagaagt
      841 accagcaggc tttgtgtgtt tgacacctgg gattcgcccg acaggtgctg acatcggaga
      901 tcaaaagcgg gtgatgacac ctcatcaagc tagagctatc ggaagtgact atattgttct
      961 tggtcgtccg atcactcagg ctacagaccc tgtcaaggct tatcaccaga ttaaggcaga
     1021 gtggaaccgt tagcagcagg atcatcatga cacatatagc tggactatga caccaaggaa
     1081 aagaggagaa aaatgacact agcagcacaa attgcaacag atttacttga gattaaggcc
     1141 gtttacctaa gaccaaagga gccctttact tgggcgtcag gcattacatc accgatttat
     1201 acggacaatc ggatcaccct ttcttatcca aaaaccagaa gcttgattga aaatggcttt
     1261 gtggagacga ttaaggcagt atttccagag gttgaggtga ttgctggcac agcaactgct
     1321 ggtattccac atggtgctat cgttgcagat aagatggacc tgccttttgc ctatatccgc
     1381 agcaagccaa aggatcatgg agcaggcaac caaatagaag ggcatgtgcg ctgcgggcaa
     1441 aaaatggtga ttatcgagga tttgatttca acaggtggat cagttctgga ggcggcagcg
     1501 gcagctagtc gcgaaggtgc tgatgtacta ggagtggtgg caatttttac ctatgaattg
     1561 ccagtagcaa gcatcaattt tgaaaaggca gggctttcct tggtgacctt gtctaattat
     1621 tcagacctca ttaaggtcgc taaggccaag ggctatattg atgctgatgg cttggccctg
     1681 ttaaaaagat ttaaggagga tcaaaagcat tggcagcatg agagttaaac agtgctgaaa
     1741 agctgctgac atgctgacta tgtcttaagg agagaaaaaa tgacttacaa agatttactt
     1801 gagataggtg agaccagtta ttatcagacg gatcgcttga cttactacaa aaatcctgtg
     1861 gtatctgagc gctattttga taattacctt agctatcgta gcatgccttc tttggctgat
     1921 ttgaaaaagg acttggccta tgtggcaaaa gagcagcagg attatcctag tcactacgcc
     1981 tttctctttt ttgctgaaaa tgaagagcta agtacagaca tgcgagctta tttgacagat
     2041 catcacttta gccttgaaaa gcacctgatc tttaccaatg agctggcaaa gcttcaccta
     2101 aaggagcgtg atatatcacc agtcactatt gaacagctct cagaaacaag cttttctgcc
     2161 tatctggctt acaaatatca ggctaatttg gcttatggtg aaacctatgc caatcaatgc
     2221 aaggctgata atgaagccaa tctattgaca aacggctcaa ccatttattt agccatcaag
     2281 gaagggaaga ttatcggaga tattacggct tgggaatgtg gcgactatat tgaaatggac
     2341 gatttcagtg tagatgaggc ctatcgtggt cgtggtatcg gtacagcctt acagcgtaag
     2401 gccagtcaag gctataagaa ggtcattctc atctcagaag aagctaatcg cgccatgtat
     2461 gagcaccaag gctatcagga ggttgcttac tactggacag cgctaaaaac atcgactaga
     2521 taagtgataa agaaacagat tataggattg aaggtgtagg ctcttatgag tatgactctt
     2581 caatcctttt tttctgagcg catttgctaa tcatacctaa tgaataagtc gtagcctgtc
     2641 tagtggctca ttttaatggc gtcttgctct gttttatgat taaatataga gaaaaagcta
     2701 ttgttagggc atgcttgttg gtctagcaag gctgatggat gataggatag ggaattgatg
     2761 atttttaaag atgcaacaga aatggcgcag gctgttcgag aaggtagggt gagcccctca
     2821 gccttagtga gagacacaat taaaaaggct caagcactca atcctgagtt gaatgctatt
     2881 acctcagagc gtttttcaga agctcttgct gaggcagcag caagggattt ttctggaaag
     2941 ccatttgctg gtgtgcctat ttttctaaag gatttagggc aggagcagga gggccaattg
     3001 gccactgcag gatcagtgtt atttaaggat tatcgtgcct caaaaacgga ttatgttgtg
     3061 cagcgactag aggagctggg ctttattatt ttaggaagaa gcaatacacc tgaatttggc
     3121 tttaaaaata ttagtgatag tcgcttacat ggtccggtaa atctgccaca ggacaagagc
     3181 cgtaatgctg gtggttcatc aggtggggca gcagctcttg tgtcctcagg aatcaccttg
     3241 ctggctcctg ctagtgacgg aggaggatcc attcggattc ctgcctcctt taatggcttg
     3301 atcggtttaa agccaagcag aggaagagtg cctgtggggc caggctctta tcgtggctgg
     3361 cagggggcgt ctgttcattt tgctctaacg aggtctattc gagacacaag tcgtcttctt
     3421 tatcacttgc aggtttatca ggtagaaagc ccttttccat tagtgccatt aaccaaagaa
     3481 gagctttttc accctttaga cagaccctta aggattgctc tttatgatca catgatagat
     3541 ggaactaccg cctctataga tgctcagaca gctttaaccg aggcctgtca ttttctaaaa
     3601 gagatggggc atgaggttgt gcgattagat aagcttcctc tagatatacc aaaggttatg
     3661 agggattact acctgatgac tagtgttgag acagctgcta tgtttgctga tagccaagaa
     3721 gcccttggtc gtcaggtgac caaagcagat atggaggtca tgacctgggc tatctaccaa
     3781 gcgggtaagg atattcttgc ttcggtctat tctcaggcgc tgcagcgctg ggaccattat
     3841 agtgctgaaa tggcaagctt tcatgagcag tatgatcttt tgctgacctt taccgccaat
     3901 acgcctgctc caaagcatgg acagttccag ccaagcaagg agctaataga taagctggct
     3961 aaggcggaat gctacccctc cagtcagcgc ctagcgctag tagaagccat gtttgagcag
     4021 agcttgttca taacccctta cacagctttg gcaaatctga caggccaacc agctcttagt
     4081 ttaccaacct atgaaacgtc tgctggattg ccgatgggca ttcaattgat agctgctaaa
     4141 gggcgagaag acttattgct gggaatagct agacagtttg aacgggctgg attgttaaag
     4201 ctacctggtt aaatattata aaacagagct aatctattat aggttagctt ttttgttaaa
     4261 tcgagcatat ctagtctctt ataagattag tcaatgctat actgtcatta ataatgaaaa
     4321 aggagttctt gatgaaaaaa ggagttgctt tactttctgt tagcttggcg agcttgctgt
     4381 tagccgcctg tgggtcacag ccatcagctc aaaaaacaag ctgggaaaag attaaagata
     4441 aaggtgtttt aaaggttgct acgcctgcga cctaccagcc aacatcgtac tataatgatg
     4501 ccaatgaatt ggtcggctat gaggttgacc tgatgaagga aattgggaaa cgccttgatc
     4561 ttaaggtgaa gttcattgaa acaggctatg atcaggcttt tacttcggtt gatagcggtc
     4621 gtgttgatgt ttctctcaat aattttgaca ttacagccaa gcggcaaaaa aaatacaaca
     4681 tctcaacgcc ttataagtat ggtgttgggg gaatgattgt tcgtgctgat ggcagctcag
     4741 gcataagcaa ggctgaccta agcgattgga aagggaaaaa agcagctggc gcctctggta
     4801 cagaatacat gaaggttgcc aagaagcaag gtgctgaatt agtcacttat gataatgtga
     4861 cgggtgatgt ttacctgaac gatgttgcta atggcagaac agactttatt cccaatgatt
     4921 atcctgcaca aaagcttttt gtggattaca tgaagtctca aaatcctaac ctcaatgtca
     4981 aaatgagtga tgtgctgtat aatccgacag cacagggcat tatcatgagt aaaaaagatg
     5041 acacccttaa gaaaaagatt gatgcggtca tcaaagacat gaaacaagat ggcagcttga
     5101 aaaccatttc aaagacatac tatgctggtc aggatttgac agttcctttt ggtaaggaca
     5161 agaaaattcc agtcattgat gccagtgatg tggactagtg ccttagacaa aggagctcta
     5221 aagcgatgct taatcttaga ttgatactag agagcttggg ctttgttttg tcaggtttgc
     5281 cctatacctt aggcatttct tttttaagct ttctaacagg ccttttgctg ggcttgcttt
     5341 tagccttttt aaggcgttct actagtcact ttagtcatta tctggtcagg agctatgtgt
     5401 ccataatgcg tggcgttcct atgattgtgg tgctctttgt cctttatttt gggcttccct
     5461 attatggctt agaactgtct gccttgttat gtgcctattt gggcttttca ctggttagtg
     5521 cagcctatat ctctgaggtc tttcgtgcct cgattgatgc tattgatcag ggacaatggg
     5581 aggcagcaag ggctttgggg ctgccttatg tcagcattgt caagcatgtg attctgcctc
     5641 aggcctttcg tattgctatt ccgcctttag gaaatgttgt gattgatatg gtcaaaagtt
     5701 cgtctttggc agctatgatt accgttcctg atatttttca aaaggctaaa attattggtg
     5761 gcagggagtg ggattacatg tctatgtata tcttggttgc ctttatttat tgggtgattg
     5821 cctttttgct ggagcgctgt cagggctttt tagaaaagag gctgcgctta ctctcttaaa
     5881 aaccgaatat ttaccctaga aatattgtat ttctagggtt tttatgataa aaatatgata
     5941 gactaaagta gcctaatcag ttagttagct ttgtcaagaa ctgactggct agagtgttgg
     6001 aggtaggata tggcagactc tattgtattt cggaaaaatc atatgatttc aactcaggcc
     6061 tttgctcgag tgctggaagc ctcagggatt aaaagaccga ctaaggacga ggctagatta
     6121 tcgcaaatgc taaagcattc caattatcta tggacagcat gggaaggtga caagttagtt
     6181 ggtgttgcta gagcccttac tgactatgct tatgtctgct atatttctga cctagcagtt
     6241 gatcaggcat atcagggtca agggataggc aagcaattgc tgtcttttat ctcagaggat
     6301 cttggagatg ctgttgctct tgtattgctg tcagcacctt cggcgatgtc ctattaccct
     6361 aagcttggct ttgaacaatc agacaaagcc ttcattattc cacgaaaacc gttttagaga
     6421 ggtatctaat gacacattca gcttggcatg atgagattaa gcaagtgtta cctaaggatt
     6481 attatcggcg tatcaatcgc tttttagatg aggtctatgc gactggagtg gtttacccgc
     6541 ccagagacaa tgtgtttaag gccttacagg taacgccatt agaagagaca agagtgctta
     6601 ttttagggca ggacccttat catggccctc ttcaagctca gggactttcc ttttcagtgc
     6661 ctgactccat tcctgctccg ccatctttgc aaaatatttt ggaggaatta gcagcagata
     6721 ttggagtaag gaatcatcac gatcttagca gctgggctga gcagggagtg ttgctcttga
     6781 atgcctgctt gaccgttcca gaaggacgcg ccaatgggca tgcaggtctc atctgggagc
     6841 cctttaccga tgcggttata aaggtcttga atgctaagga taggcctgtt gtgtttatcc
     6901 tctggggagc ctatgcgaga agaaagaagg ccttgattac taatccgatt caccatgtta
     6961 tcgaaagccc tcaccctagc cctctgtcag cctatcgtgg cttttttggc agcaagccct
     7021 tttcaagagc taacgccatt ttagaaaaag aaggcctagg acagattgac tggctgcgct
     7081 aggcattgag gcaggctatt atggctaagc aggacgattt accaataaag tatccggctt
     7141 tggagacttg ggtataccta gctaaataga gattgatgat atcagggatc aagacagtta
     7201 cgtccgatat gtcaagcaaa acaaataatc actgcctaga taaatcagaa attgctaggg
     7261 ttatgcttga ttatcctgat aagcagataa gtagatttga cataggaggg gtcatgttat
     7321 taattaaaaa tgggcgtgtg atggatccaa aatcacagct agatcaggtg gcagatgtct
     7381 taattgataa tggaaggatt ttacggattg ctccagacat tgagcatgat gaggtagagc
     7441 agatcgatgc cagtggactt gttgttgctc ctggtttagt ggatattcat gttcatttta
     7501 gagagccggg tcaaacgcac aaggaggaca ttcatacagg tgctctggca gcagctgctg
     7561 gtggggtgac aacagtagtc atgatggcaa acaccaatcc tgttatatca gatacggaaa
     7621 ccttacaggc tgttctagca agtgctgcta aagaaaaaat taacatttat accaatgcta
     7681 gtgtgaccaa gcggttcaat ggccaagagc taacagactt taaagcgctc ttagcagctg
     7741 gtgcggtcag tttttctgat gatggcattc ctttagagag ctccaaggtc ttaaaggaag
     7801 cattggattt ggctaaggcc aacaagacct tcattgccct gcatgaggag gatccccaat
     7861 taaacggtgt ccttggcttc aatgagcata tcgctaagga tcattttcat ttttgtggcg
     7921 ctactggtgt ggcagaatat agtatgattg ccagagatgt gatgattgcc tatgatcgac
     7981 aagctcatgt tcatattcaa catttatcta aggctgagtc tgttaaggta gttgcctttg
     8041 ctcagcagtt aggtgccaag gtcacagccg aggcaacacc gcagcatttt tctaaaacag
     8101 aagacctttt acggcttgca ggggcaaatg ccaagatgaa tccgcctcta agaacagaac
     8161 aagatagatt agcagttatt gaggggctca aatcaggtgt catagctatt attgcaacgg
     8221 atcatgcacc acatcatcgt gatgaaaagg ccgttgctga tctgaccaag gcaccatctg
     8281 gaatgaccgg cttagaaacc tcattgtcat taggcctgac aaatcttgtg gagccgagcc
     8341 atctttcatt gatggcgtta ttagagaaaa tgaccattaa tccagcctca ctatatagct
     8401 ttgatgctgg ttatttggct gagtctggcc ctgctgatct tgttattttt gctgacaagg
     8461 aggagcgttt ggtaacagaa gcctttgctt caaaggctag taattcacct tttattggcg
     8521 aaaccctaaa gggagttgtg aaatacacca ttgctaaggg acaaattgtt tatcaggcag
     8581 acaactaatc aacacttaaa aagctgagca tctgatagta actgatgctc agctttttga
     8641 tttagtgatg gcttgcgggc tgctgcttgc ttaagttcaa gccccaagga atgagatttt
     8701 cagattgctg cttgattcgc ttcatattat cctgatgcct taggataatg attgctgcta
     8761 gcacaacgat ggtaatggtt aatagccaat cgtagctagg caataaaaag tgggcggcag
     8821 gaaaagtcag aacgctaatc acagctacta cagacgctgt tagactagct agtgaaatca
     8881 tgctaaataa ataaagcgtt agcacaaaca cagccgctaa aaaaaggaga tagagtgggg
     8941 caaagcctag caagacacca gcactggttg cgactgcctt tcctcccttg aagccagcga
     9001 aaataggaaa ggtatgccct aggacagcaa aaaagccaat agtaattggt gagatattgc
     9061 tagcgccaac caaaaccgga agaagcgtgg caagcgtgcc cttaaaaata tcaatcaata
     9121 aggttgcagc accagctttt agcccaagaa tccgaaacgt attggtcgta ccggtattac
     9181 ctgagccatg ctcacgcagg ttgatgttat agaaatactg tccaatccat aagcctgttg
     9241 gaatggagcc aagtaaatat gctgtaagaa ttaataggat caatttcata acatacatta
     9301 tatcataatg attgatttaa gcggaagcag ttacaaagaa ttacgaaaaa atcttaaatt
     9361 attttgcaaa attctcaaaa aacctgtaag ataaaaaaga tgaaaacgtc tggaggtcaa
     9421 cttggctaag aaagaaataa gcataacaaa ttataatgat gatgccattc aggtcctaga
     9481 gggcttagag gcagttcgta aaagaccagg gatgtatatc ggatcaaccg atgcaaccgg
     9541 acttcaccat ttgatttggg agattgtcga caatgctgtt gacgaggcct tatctggctt
     9601 tggaaatgag atcgatgtga cgctaaacaa ggatggttct gccaccattt ctgacagcgg
     9661 acgaggcatg ccgaccggac agcacgccct tggtatacca actgttcagg tcatctttac
     9721 catcttgcat gcaggtggta aatttggtca aggaggctat aaaacctcag gaggcctgca
     9781 tggtgtgggc tcttcagttg taaatgccct atcgtcatgg ctagaggtgg aaatcacgag
     9841 agacggagcg gtttacaagc agcgctttga aaatggcggt aggccagtga caggcttaga
     9901 aaaaatagct acagctccaa aaagcaaatc agggacaagg gttactttca tgcctgatga
     9961 caagattttt tcgacaactg agttcaagtg gaatactatc gcagagcgtc taaaggaatc
    10021 tgcttttctg ctaaagacgg ttaaaatgac cctgactgat ctacgaggtg acgatccggt
    10081 cgttgaggaa tttcattatg aaaatggtgt tcaggatttt gttgcctatc tcaatgagga
    10141 caaggaaacc ttgactcctg tgatttacat ggaagggcag gagcaggatt ttcaggttga
    10201 ggtcgctttg caatacaatg atgggttttc agataacatt ttgtcctttg ttaacaatgt
    10261 taggacaaag gacggtggca gccatgaaac tggcttaaaa tcagctatta caaaggccat
    10321 gaatgactat gcccgcaaaa ccagcctact aaaggaaaag gataaaaact tggagggctc
    10381 agattatcgt gagggcttgt ctgcagtgtt atcgatcctt gtaccagagc agcatttgca
    10441 atttgaaggg caaacaaagg acaagctagg aagcccactg gcaaggccga tcgttgagag
    10501 cattgtatca gaaaagctga ccttcttttt acttgaaaat ggtgagctgg caggtcattt
    10561 gattcgtaag gctatcaagg caagagacgc gcgtgaggca gccagaagag cgcgtgatga
    10621 gtctcgaaat ggtaagaaaa acaaaaagga caaggggctt ctttctggga aattaactcc
    10681 agcccagtcc aaaaatccta agaaaaacga gctgtaccta gtcgaggggg actcagctgg
    10741 aggctcagct aagcagggca gggatcgtaa atttcaggca attctcccct tacgtggtaa
    10801 ggttttgaac acagaaaagg ccaagatggc tgatattctc aaaaatgagg aaatcaatac
    10861 aatggtttat accattggcg caggtgttgg tgctgatttc aatcttgatg atattaatta
    10921 cgacaagatt attatcatga ccgatgctga tacggatggg gctcatattc agaccctgct
    10981 gctgaccttt ttctaccgtt atatgcggcc gctggttgaa gcaggacatg tctatattgc
    11041 cttgcctcct ctttataaaa tgtcaaaggg taaaggcaaa tcggagaagg tttcctatgc
    11101 ttggacagat ggtgagctgg aggatcttcg caaggaattt ggtaaaggtg caagtctcca
    11161 acgctataag ggacttgggg agatgaatgc cgatcagcta tgggaaacca cgatggaccc
    11221 tgacacacga acccttatcc gagtgacgat tgatgacctg gctagggcag agcgacgcgt
    11281 ttcagtcctc atgggagaca aggctgcccc acgccgtcaa tggattgagg acaatgtcac
    11341 ctttaccttg gaggaaaata cggtttttta aggcattttt cctaaggagg gttctaaaat
    11401 atctcatatc aaattgctat tcatgtgctc agcattcatt tatcaaggat tgtaatcatt
    11461 gaggtaacag tgatgaagct agatatttgt caacaaagct acagtcttca gtggggaggc
    11521 acctattatt ttgcattgac agattatccc aatatcaagg cttgggaact ggaaaagcta
    11581 gcagcctttt gtgcctacga aaaatggaat catcgtcaaa cagacattag ctgtcaggac
    11641 agcaagcttc ttgaagaggt tcatcaattt cttgaagcac atgcttgtgc ctatctcttt
    11701 aggcctagct gtaaattggt ggcttcaaca tttaacatca atggagaggc agtctgttgt
    11761 ccttatttaa gtcatacctg cactgtagcg gctgctctaa gcatttttaa gacaggaagg
    11821 ctattgtctg ctgtaagagc ttttggggta acggcacagg agttggctag gagtgatcga
    11881 aatgctgctg gtgatcctgc tgattatttt cattatgtga tgcttggctg gtccaatacg
    11941 acctcaggct atcgcttggc tatggagaga ttgcttaatc gtatgccaaa tgaaaaggac
    12001 ttaagagagc attttgtacc cggagttagc tttcactata gctattctga tatttgtcag
    12061 atgaaaggct atgtttttga tggctatcac cctgccaaga tcaaagacga gcttagtttg
    12121 gaggaattgc aggcttgcat tattcctaaa agctggcagc agcgctttga agcaattatt
    12181 ccaaaggcct tacgctcaag ggttcattac ctagactata aaggcgaagg cttggtcgag
    12241 tggtctgata gggtttatca gctgttaaga gtgatcagtg acagctagct gtaaataggc
    12301 tagctttata ctattttttg aatataatag acaatctaac agaaaggaaa gctcagtgag
    12361 aggtctcttg ctgggtgtgg gatggatttc ctagaaactg ctaatcctag cgatagggga
    12421 gcgtagcgag cccattctga aagctcctgc cgtagtgaaa agaagataat cgcttacgat
    12481 tatcttcgag ggaaatttcg agccgaagtc tcgaaattta ggaatggaac cgtaggttcg
    12541 cttctgtccc cactacctaa aggaactttc aaaaaaaact aattaaagaa agagatatct
    12601 ttctgaaaga aacaaagaaa ggaatgttca gctagtttac taactgaaca cgggactatt
    12661 tttcctagaa aaatcggtaa cctcctagtg tccaaggaca cgtcgtcagt tccagcattt
    12721 tttacggaaa aatttcgcaa gcgaaacgtc cctttgtatc ttatgagtaa tattcaaaac
    12781 atgtcccttg aggacatcat gggagagcgt tttggacgct actccaaata catcattcag
    12841 gagcgagcgc ttcctgatat tcgagatggt ctaaagcctg ttcagcgccg cattctttat
    12901 tctatgaata aggacggtaa tacctttgaa aagggctacc gcaagtcagc caagtctgtt
    12961 ggtaatatca tgggcaattt ccacccgcat ggagattctt cgatctatga cgctatggta
    13021 cgcatgagtc aggattggaa gaatcgtgaa attcttgtgg aaatgcatgg caataacggc
    13081 tcgatggacg gtgatccacc ggcagctatg cggtacactg aggcaagatt atctgaaatt
    13141 gctggttacc tgctacagga catcgataaa aaaacagtgc catttgcttg gaattttgac
    13201 gataccgaaa aagagccaac agtattgcca gctgcctttc caaatctatt ggtcaatggc
    13261 tcatcaggga tctcagcagg ctatgctaca gatattccac cacataattt gtcagaggtg
    13321 atcgatgctg ttatttatat gattgaccac ccaaatgcca agctggataa gttaatggag
    13381 ctattgccgg gtcctgattt tccaacaggt ggtattatcc aaggagcagc cgaaattaaa
    13441 aaagcctacg aaacaggtaa gagccgcgtt gttgttcgct ccagaactga aattgaggat
    13501 ctaaagggag gcaagcagca gatcattgtg accgaacttc cttatgaggt caataaagct
    13561 gtcctagtta aaaaaattga tgatgttcgg gttaataaca aggttccaga catagcagag
    13621 gtgcgtgatg agtcagaccg tacagggcta cgcattgcta ttgagctcaa aaaagacgct
    13681 gacagccaaa ccatcttgaa ttatttgttg aagtataccg agcttcaagt caattataat
    13741 tttaatatgg ttgcgattga tcattttacg cctcgtcagg ttggattgca aaaaatctta
    13801 tcaagctata tcgctcaccg caaaagtatt attatcaagc gctctcagtt tgacaaggaa
    13861 aaggctgaaa agagattgca tattgttgag ggcttgatac gtgtcttatc tattttagat
    13921 gagattatcg cgctgatccg agcttctgac aataaggctg acgccaagga aaacctaaag
    13981 gtcagctatg atttttcaga ggaacaagca gaggctatcg taaccttaca gctttatcga
    14041 ctgaccaata cagatattgt taccctccag caggaagaac atgacctaag agagctcatc
    14101 acaactctct ctgccattat tggtgatgaa gcaaccatgt ataacgtgat gaagcgtgag
    14161 ctaagagagg tcaagaaaaa gtttgcaggg ccgcgtttat cagagctgca ggctgaaagc
    14221 caagcgattg aaattgattc tgctagtctt attttggagg aagaaacctt tgtcagtgtg
    14281 actcagggag gctatatcaa gcgaacaagc cctaggtcat ttcacgcctc aagccttgag
    14341 gaaattggta agcgtgatga tgatcatctg atctttgtta agcaggctaa gacaacagac
    14401 cacctgttac tctttactaa tttaggtaat gttatttacc gtccggtcta tgagctgact
    14461 gacttgcgct ggaaggacat cggggagcat ttatcacagg ctattgctaa ttttgctgct
    14521 gatgagctgg tgatatatgc tgagttgatc cagtcctttg aagagggact atatatctca
    14581 gtgacacagc atggactgat taaacggttt gagcgcaagg agctgacgcc ttggcgaacc
    14641 tacaaatcaa aatcaattaa atacgccaag ctaaaagaca tagatgatcg cattgtggca
    14701 atagcaccaa ttatcatgga agatcttctt ttggtgacgc agcagggcta cgccttgcgg
    14761 ttttctagcc aagaaatacc gattcagggc ctaaaggctg ccggagttaa aggaattaac
    14821 ctaaaggctc aggattactt ggtttctgcc tgcccagtca atgctgattc cttctttgtg
    14881 ctgacgcaaa gaggagcact aaagcgagtg gcgattgctg atattccaca gaccagccga
    14941 gctaacagag gtctgccggt gttacgagaa ttaaagacca agccacacag agttttcttg
    15001 gcaggaatgg taaaaggaga tactacaaca ggtaccattg acttatttac acatgattca
    15061 gaggacacag ctagtgacca gcaattagag gttattagta agactggtca acaataccag
    15121 cttgctctca atagcctgtc tctatcagat aggacaagta atggctcctt tatttcagag
    15181 agcatttcag atcaggaggt cgctgctgca aggctcatct agccaaagct ttttcgctgt
    15241 accagtgagg gctctgagtc tttcatcgaa aaaagatgca aaacaatgaa gaaaagaata
    15301 caaaaagaaa agaggtagga taatgacaac agctattgat tgggaaaact taggctttga
    15361 ataccgtaag ctgccatttc gctatgtatc atattacaag gacggcaaat gggacgcagg
    15421 tcgcttaaca gaagatgcta ccctgcacat ctcagaaagt gcaccagctc tgcattatgg
    15481 gcaacaagcc tttgaaggct taaaggccta tcgcactaag aacggctcta ttcagctatt
    15541 tcgcccagac cgcaatgcag ctcgcttaca ggcaacagct gaccgtttgc tgatgccaca
    15601 ggtatctacc gagcaattca ttgacgccgt taagcaagtg gtaaaggcaa atgaggattt
    15661 tgtaccgcca tatggaactg gtgctaccct ttaccttaga cccttgttaa ttggtgttgg
    15721 cgatattatc ggtgttaagc ctgctaacga atatatattt atagtttttg ccatgcctgt
    15781 tggcaattac tttaaaggcg ggcttgcgcc gaccaacttt atcgtctctg aggattatga
    15841 tagagcagct ccttatggca ctggagctgc caaggttggt gggaactatg caggtagctt
    15901 attgccagga aaagcagcta agacagcagg gtattcagat gtgatttacc tagatccagc
    15961 aactcacact aagattgaag aggtcggagc cgctaatttc tttggcatca ctgccaataa
    16021 tgaatttatt acgccgctta gcccatcaat cttgccttca attaccaaat actccttact
    16081 ccaattagcc gaagaaaggc ttggtatgac cgctattgag ggtgatgtgc cgattaatga
    16141 tttggaccga tttgttgagg caggagcttg tgggacagct gctgtgatct caccaattgg
    16201 aggcattcag tatcaggata agctacatgt cttttacagc gagactgagg ttggtccagt
    16261 gacacgtcga ttatacgatg agctggtcgg tatccaattc ggtgatatcg aagcaccaga
    16321 aggctggatt gtagctattg attaaaataa gtgaagcttg ctattgcaag ctcttttgat
    16381 tttgtgtaaa atagacaagg cgaggtgaag tgatgagtaa aaaagagaaa aaaattgaac
    16441 tgcaattatg cgatcaacaa gtaacagtca acaataccaa gatagacggt tatcagttac
    16501 aaattggcaa gcgtgtcgtt ggcgagattg cagagcttga tggcaagttt gctgtcttaa
    16561 aagacagcac agtagatgct ttttttaaaa cattagagca agcagttgaa aatattattg
    16621 aaaactataa tttgaaccac taaaaatgct taaaaagact tgtcagctta caaaaactat
    16681 ggtagaatag tttttgttgt tacggaaaga tagcgaagag gctaaacgcg gcggactgta
    16741 aatccgctcc tttgggttcg ggggttcgaa tccctctctt tccatgccta agctattagg
    16801 ttcattgttt taatgatgat attggggtat agccaagcgg taaggcaagg gactttgact
    16861 ccctcatgcg ttggttcgaa tccagctacc ccagtcagag gtatcagatt agcgtctgag
    16921 atcgtcaagg ataaaagttg ttgtcattgc gggttacctt gagaaaatat attgttatca
    16981 aaagctagca taagctagct tttgttggag gattttttag aatgaatgaa tttgaagatt
    17041 tgctaaacag tgttagcgaa gtcaatcctg gtgatgttgt cactgcggag gttttgacag
    17101 ttgataacgg tcaagcaaac gttgttattg aaggcacagg tgttgaaggc gttttgacac
    17161 ttcgtgaatt gactaacgat cgtgaagctg atattaatga ctatgttaaa gctggcgaca
    17221 ccgttgaagt gcttgttctt cgtcaagttg taggtaaaga tactgataca gttactttcc
    17281 tagtatctaa aaaacgtttg gaagctcgta aggcatggga caagcttatt ggtcgtgaag
    17341 gtgaagtcgt tactgttaag gggactcgtg ctgttaaagg tggactttca gttgaatttg
    17401 aagggcttcg cggatttatc cctgcttcaa tgattgacac tcgttttgtt cgcaatacag
    17461 aaaagtttgt cggtcaagaa tttgacgcta aaatcaaaga agttgatgca gcagaaaacc
    17521 gctttatctt atcacgtcgt gaggttgttg aagaagcagc taagcaagca cgtgacaaag
    17581 tcttttcaac actttcagaa ggttcagtgg taactggtac tgttgcgcgt ttgacaagct
    17641 ttggtgcttt tattgatctt ggtggtgttg acggtcttgt tcacgtaact gagctctcac
    17701 atgagcgtaa tgtgtcgcct aaatcagttg tttctgttgg tgaagaggtt gaggtgaagg
    17761 tacttgctct tgatgaggaa gcaggtcgcg tatcactatc acttaaagca acaacacctg
    17821 gaccttggga tggcgttgag caaaagcttg cacaaggtga tgttatcgaa ggtaaggtta
    17881 agcgcttgac tgactttggt gcttttgttg aggtattacc tggaattgat ggacttgtac
    17941 acatttcaca aatctcacac aagcgtgttg aaaatccaaa ggacgtgctt actgtaggtc
    18001 aagaggtaac tgttaaggtt cttgacgtta acgctgctga tgagcgtgta tcattgtcaa
    18061 tcaaggcact tgaagagcgt ccagcacaag cagagggtga aaaggaagaa aaacgtcaat
    18121 cacgtccacg tcatcaaaaa cgtgaagcta agcgtgatta tgagcttcca gaaacacaaa
    18181 ctggattttc aatggctgac ctttttggtg atattgaatt ataatactat aaaaa
//
LOCUS       DARYLD010000042        18175 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.042, whole genome shotgun sequence.
ACCESSION   DARYLD010000042 DARYLD010000000
VERSION     DARYLD010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18175
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            62..298
                     /locus_tag="TU651_001350"
     CDS             62..298
                     /locus_tag="TU651_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL0897341.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TU651_001351"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TU651_001351"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL0897342.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TU651_001352"
     CDS             1637..1825
                     /locus_tag="TU651_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL0897343.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TU651_001353"
     CDS             1857..2735
                     /locus_tag="TU651_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0897344.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TU651_001354"
     CDS             2749..2907
                     /locus_tag="TU651_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897345.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TU651_001355"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TU651_001355"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL0897346.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4880..7285
                     /locus_tag="TU651_001356"
     CDS             4880..7285
                     /locus_tag="TU651_001356"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL0897347.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVETVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TU651_001357"
     CDS             7520..8596
                     /locus_tag="TU651_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897348.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TU651_001358"
     CDS             8606..9310
                     /locus_tag="TU651_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897349.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
     gene            9649..10773
                     /locus_tag="TU651_001359"
     CDS             9649..10773
                     /locus_tag="TU651_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL0897350.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(10935..11528)
                     /locus_tag="TU651_001360"
                     /pseudo
     CDS             complement(10935..11528)
                     /locus_tag="TU651_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            11597..13570
                     /locus_tag="TU651_001361"
     CDS             11597..13570
                     /locus_tag="TU651_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL0897351.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            13594..15036
                     /locus_tag="TU651_001362"
     CDS             13594..15036
                     /locus_tag="TU651_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL0897352.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            15117..15926
                     /locus_tag="TU651_001363"
     CDS             15117..15926
                     /locus_tag="TU651_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL0897353.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            16238..17395
                     /locus_tag="TU651_001364"
     CDS             16238..17395
                     /locus_tag="TU651_001364"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0897354.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            17481..>18175
                     /locus_tag="TU651_001365"
     CDS             17481..>18175
                     /locus_tag="TU651_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0897355.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILE"
BASE COUNT         5633 a         3659 c         4096 g         4787 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaactgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaattat ctcaaaagtt ccttttactg atatttaata ttttctgtat ttttaattta
     9421 tagaaaaata aagaaacatg ctgagagttg atcaaaacac ttactatact tacgatgaca
     9481 agtaacttgc taaagtaatg gttgacatat aattgtaaaa aaacagaaat aaaaaaaaaa
     9541 cggtttaata ttgacctaat tggcaataac gtttacaata aaggtataat tatctgccgt
     9601 tgataattag gagacatcat gtctagataa aaacaaaagg ggaataaaat ggcaaaaaaa
     9661 gaaatgaagt tttaccttcg taaatcagcc tttgggctag cttcagtatc agcagccctc
     9721 ttggttggtg cggcagctgt atcagcagat tctgttgagt cagctgggcc tgtagcagtt
     9781 gctgttacag atagtttaga tagtgaagcc gcagctacaa aggcagaagc tgatctagtt
     9841 gctgcaaaag cagacctagc agcagcagaa gtagcaatca cagctgcaaa agctgaattt
     9901 gacaccgctc aagcagacct agctaccgct gaagctacta tcgcagagct tgagcaaaaa
     9961 attcctgagt tagagaaaaa aattcaagaa gctcaggaaa aactaaacta tgaaaatcga
    10021 ccatcaccta aacgtgtggg cagtgatgat gaagatgaca cagtagctag aaagcttatg
    10081 tcagaaaagg aagctcttaa ggctgagctt caaaagacta aagaagcgct agatacagct
    10141 aaaagagctt atgctggcat cgaagaaaga aaacaagtag cagcaactaa gctagatgca
    10201 gctaacaagg cttttgctgg agttgaagaa aagcatgctc aagcaatggc tgcatttgga
    10261 gcagcattcg cagcatacaa ggaagctgtt aaggctgaat tgaaggcagc aggtgctagc
    10321 gacttctaca ccaagaagat tgactctgcc gacacagttg acggtgttaa gacactcaga
    10381 gaaatgatct tagactcaat tgctaagcca gaggttgaac cagaggctaa gcctgaacct
    10441 aagccagaac caaaacctga gccaaaacct gagccaaaac cagaacctaa gccagaacca
    10501 aaacctgagc ctaagccaga gccaaaacca gaacctaagc ctgagcctaa gccagaacca
    10561 aaaccagaac ctaagccaaa acctcaacct aaaccagctc cagctccaaa acctgaagct
    10621 aagaaggaag agaagaaagc agcgcctaag caagacacca acaaattgcc atcaacaggt
    10681 gaagctacaa atccattctt caccgcggca gctcttgcag ttatggcagg tgcaggcgtg
    10741 gctgcagtgt caacaagacg caaagaaaac taagccttat accccagtgg taaagcttga
    10801 gcgagaacaa tttgttctcg cttttttagt gtcttaaaag cacctacagc aatcataggt
    10861 gcttaacaag atatgtctaa cgattgctat cagctgtaga gaataaaaag gagagactaa
    10921 gccttgctca caagctactt agaccgaagg agctttagga tttctatgat ttgctgaggg
    10981 gagtccttac agccgcagct gatccactta atgatgatga cctcaataga ggcaatgtat
    11041 agctcaaaaa catatttttg ggtaacttca ggataatctt gtgattctgc acaattcatg
    11101 aggttggaat aggaaataat atccctaata taatgattaa aaattttata aatattagga
    11161 taataaagga ttaagctttg catgacctcc tgattgtcag agaggtagtt taggattttt
    11221 aaggtaatag ttgtatcaag tgatggggat tggtaaatga tagaggtgat atcatctagg
    11281 taaacgccga tcatttccct atctaagtcc ttcttagagt tgaaataatg ttaaaaggtt
    11341 gttcgactga tattagaagc cttgctaata tctgatacag taatactgtc cttatccttg
    11401 tattgtagta gtcggcagta gcttttaatt atttttttac aagtttgttt atttttatcc
    11461 attgtatcat taactcctta aaattgaaca ttaatgttaa ttttgtacat aatatttttt
    11521 gctaacatta tacaatgatg aacgtgattt gtaaaattaa attttgcaaa tcaataatgt
    11581 aaaaggagga ttttgtttga aacaactgac aaagatcgtt agtgtggtct tgttgctggt
    11641 ctttaccctt agtgctagcc tgcacaaggt tcgggcaact aatcttagtg acaacatcac
    11701 atcattgacg gttgcttctt catcactccg agatggagag agaacgacgg taaaggttgc
    11761 gtttgatgac aaaaaacaga aaatcaaggc aggggatacg atagaggtca cctggcctac
    11821 aagtggtaat gtctacattc agggctttaa taaaaccata ccgcttaata ttagaggggt
    11881 agatgttggt accttggagg tcacgctaga caaggctgtt ttcacattca atcaaaatat
    11941 tgaaacaatg catgatgtct ctggttgggg agagtttgat attactgtta gaaatgtgac
    12001 acaaaccacc gctgaaacat caggaacgac cacagtaaag gtaggcaatc gcactgctac
    12061 tatcactgtt actaagcctg aggcaggcac tggtaccagc tcattttatt ataagactgg
    12121 tgatatgcag cccaatgata ctgagcgtgt gagatggttc ctgctgatta acaacaacaa
    12181 ggaatgggtg gccaatactg ttacagtcga agacgatatt caaggtggtc aaaccttgga
    12241 tatgagcagc tttgacatca ccgtatctgg ttatcgtaac gagcgcttcg ttggggaaaa
    12301 cgctctgaca gagtttcata caacatttcc aaattctgtc attacggcaa cagataatca
    12361 cattagtgtg cggttagatc aatatgatgc ctcacaaaac actgtcaaca ttgcttataa
    12421 gacaaagata acggactttg accaaaaaga atttgccaac aacagtaaaa tctggtacca
    12481 gattttatac aaggatcagg tatcgggtca agagtcaaac caccaagtag ccaatatcaa
    12541 tgctaacggc ggggttgatg gcagtcgcta taccagcttt actgtcaaga aaatttggaa
    12601 tgacaaggaa aatcaagacg gtaagcgtcc aaagactatt actgttcagc tttacgccaa
    12661 tgatcagaaa gttaatgata agaccattga attgagtgat actaatagct ggcaagcaag
    12721 ttttggtaag ctggataagt atgacagtca gaaccaaaaa attacctaca gtgtcaagga
    12781 agtgatggtt cctgttggct accaatcgca ggttgagggg gatagtggag taggatttac
    12841 cattaccaac acctatacac cagaggtcat tagcattacc ggtcaaaaaa cttgggacga
    12901 cagggaaaac caagacggta aacgtcctaa ggagattacg gttcgtttat tggcaaatga
    12961 cgctgcaact gacaaggtag caactgcttc agagcaaacc ggctggaagt atacatttac
    13021 caatctaccg aaatacaaag atggtaaaca gatcacctac acgatccaag aggaccctgt
    13081 ggcagattac accacaacca ttcagggatt tgatattacc aatcatcatg aggtagcctt
    13141 gaccagccta aaggtcatca aggtttggaa tgataaggac gattattacc ataaacgtcc
    13201 caaggagatt accattttgc taaaggcaga tggcaaggtg attcgtgaac atcagatgac
    13261 accggatcag caaggaaaat gggaatacac ctttgaccag ctgccggtct atcaggcagg
    13321 caagaaaatc agctacagca ttgaggaaaa acaggttgct ggctatcaag cccctgtcta
    13381 tgaggttgat gaaggcttga agcaggtcac tgtaaccaac acccttaacc caagctacaa
    13441 gctgcctgac accggaggac aaggagtgaa atggtacctg ttaatcggtg gcggttttat
    13501 catcgtcgca atccttgtac tgatcagcct ttatcaaaaa cacaagcgcc ataacatgtc
    13561 aaaaccataa catgtaatag aggagagaga gctatgaaaa caatcaaatt aatcttgacg
    13621 agcttgcttg tcaccttcct aacaatgctg tcaggaaagg catttgctga tacagcaagc
    13681 tataccatca ctgttgaggg agctacagca ggtcacacct atgaggctta tcagattttc
    13741 aagggtgact tgtttgacag taccctatca aacatcacat ggggaggtgg tgttacacct
    13801 tttgaatttg atggttcaaa agacgctgct aagattgcag agggattgaa ggaagcaaat
    13861 gcagctgcct ttgccaagga agcaggtaag cacttgacag caaccattgc aggaacagga
    13921 acacatgcaa tcaccgttaa cgaggctggc tactacctca tcaaggacaa aaatgattct
    13981 caaacaggca agcatgacgc ctacacctca tttgtcctga aggttgttaa aaacaccagc
    14041 ttcaaaccaa aatctgctat cccaacagtc cttaaaaagg tcaaggaccg taatgacaag
    14101 acaggtcttg agacaggctg gcaagattca gctgactatg acaaaaatga caaggtgcca
    14161 ttccagctaa ccgcaaccct accgtcaaat tacgatgcct ttcaagaata ctaccttgaa
    14221 tttgtagata ccttatcaaa agggctaagc tacaacaaag acgccaaggt ctatgtggtt
    14281 aatggagata ctcgtcaaga tattactaat tcatttacag ttagtgaaga tggttcatct
    14341 tttaaaatca ataacctaaa ggctgttcag ggagtaacaa taacagctac cagtaagatc
    14401 gttgtcgaat acactgctac cctcaatgac caagcggcca tcggcaaaaa aggaaatcca
    14461 aacgaagttg ctttgaaata ctcaaacgat ccaaacgctc ttggaaaagg agaggagtct
    14521 ccaaaagggg agacaccaaa agacaaggtt atcgttttca cctataaaac tatcatcaat
    14581 aaggttgatc aagatcaaaa agccctaaaa ggtgcaggct ttacccttta taagctggtc
    14641 aaaggtgata atggcgagga aaaatatcaa atagtccaag aaattaaagc aggggataca
    14701 actagctttg agtttgttgg acttgacgct ggtgattaca agctcagcga aacaacaaca
    14761 cctggcggtt acaacactat tgcagatgtc atgttcagca ttgtagcgca gcatgaaacc
    14821 gagtcagacg atcctcagtt gactagccta accgttgaca aagcaactgg cttcactgct
    14881 gatacagaag ctggtaccgt atccgcaact attgttaata aaaaagggtc tatcctccct
    14941 tcgacaggaa gtatcggaac aaccatgctc tatgtgtttg gagtaatgct aatgacaata
    15001 tcaacgctgt ttatctttcg tcagaaacag caataagatc gtgtgagtag gtaaaaagaa
    15061 gtggatagac gtcttaccaa gacctattca cctctttttt tgatagaggc tatagaatga
    15121 agaaaagtgt cattttttgg agtgtgattt tggtggcagg ctgtctgatt gtcctttacc
    15181 ccacccttag taactattgg aatgcacagc accaatcaca gctcatcgct gactatgtct
    15241 caagcacgca agctttgaga cataaggata gtcagctcat gctagaagca gccaatcagt
    15301 acaatcagca gctaaaagct aaccatgatc ctgatttaac cttgaccgat agtgaggcag
    15361 aagcctatca gcagcagctg gatctgacaa atacaggtat catggcctac atagatattc
    15421 caaaggtgca tgagcggctg ccgatttatc atggcaccga tgaggagatc ctacaggtgg
    15481 ctatcggtca tcttgcaggc acctctttgc ctgtaggtgg caagggaaca catgctgtca
    15541 tctcaggaca tcgagggtta ccctctgcca agctatttac caatattgat aagctgagga
    15601 ttaacgatac ctttaccatc accagtctta ataggactat gacctatcag gtggataaga
    15661 ttgctaccgt tttgcctgat gatgtcagcc tcttaaggat agaggagggg aaggatctgg
    15721 taaccttggt cacctgtacc ccctacggtg tcaacacgca tcggctcttg gtcagagggc
    15781 atcgtatcaa aacagcgaca ccaaccgctg caagaggatc tcaaaagcct agtaggctaa
    15841 tcctctggct cttgctaatc agtgcattag ggctatctct cgtactaata ggcacttggc
    15901 gctggcgtag gaggtctaaa gcatgagcag gctttccaga agcaactaag tcaaatcatc
    15961 aacccttgat aggttactga ggacctatca ggggattttt tagtgctaaa ttgcgactat
    16021 gattaaaaac acagaaatcg tttttttttc ttagtgaccg aaaacgcttt aaaagagcga
    16081 gcatttggag ccttcaaaag tgacatctga gcataacatg ataaaattga cttataaaac
    16141 ctaataaaat gataaaagga ggagagttaa cgacaaaata ttagatattt atttaatttg
    16201 ttgtttttga aaacgtttta taataagaaa ggatagcatg atgaaaaaac aatcattcac
    16261 acactcacgt aaacctaaat tcggtatgag aaaattatct attggccttg cctcatgtat
    16321 gctaggaatg atgttcctaa caacaggaca tgtttctggt gaggtagttg aagtttggcc
    16381 taatgggcaa aatcctaatg gtaaaataga aattctaagt caaactgagc actctgagca
    16441 tttacagaaa ttacgcgata ttgaagattt ccaagctcaa aagcaagctg atcatgttcg
    16501 ttacactaaa tggttagatg gggtaactgt tgatgagcat gaattcagaa aaatcaagga
    16561 atatgacaca gaatattatg taacacctct tttaagtggt aaaggttact atgatatcaa
    16621 taaagatttc aatcaagata gtgataaatg tgctgccgct gtagcggcta atatgttcca
    16681 ttattggttt gatagaaata gagacagtat taatcgtttc ttaagtcaaa gtccaggtga
    16741 aaatggtgtt attaaacttg aaaatgaaaa aacaatagaa gtatcaaaat ttttagaaac
    16801 ttaccgtagt gatggtgatt atcttgataa aagtccgttt tttgacctta tcagtaacag
    16861 ctttaaaggt cctgtttggg caaataagct attggatgct tacattaacg gctatggtta
    16921 tatccataaa tttgctaaaa atactccaca ttctaaaaat aataatagta aatttaattt
    16981 ctttaaaaaa gtatttgatg gtaatctctt gacagatatt caccaaattt ttgattataa
    17041 cactttttca gataaattaa gtgaggctct ctatactggt aaagccattg gattggccta
    17101 cggacctgga gacttgcgtc gttcactagg tcatattatt tctgtctggg gagctgatct
    17161 tgacgatcag aatcgcgtgg tagctattta tgtaactgat tctgatgata aaaagttaac
    17221 tataggaaat gagagagttg gtttgaagcg atataaagta tctagcgatg atcaaggtcg
    17281 tgctcgtctg acgactcgtg ataaagataa cacaggtggt gaaattcgat ctattgaaac
    17341 attagatatg ggtacacaag agtgggcaga ttacttcaac aagacagaaa aataacaata
    17401 acccctacac atatatgatt actccagata aagcacacag caatagactc agccagtaag
    17461 gaaaggacga taacaaaacg atgctaacaa accaaacggg gtacaggcat agacttagta
    17521 agcagaagct acctatcagc atggtttcct gcttgctagg aatgggggtg ctaacctctc
    17581 caacattaat ctcagctgat gatagttctc ctactatcat cattaaatcg ggtgcaggta
    17641 tgacaattga tcctcaatta ccgaaaactc tcctttctaa acccgaagag aaaccagagg
    17701 aaacacctaa acttccagat gagcgacatt atggtgatga tgtcagaccg gaagaaacac
    17761 caaagcttcc agacgagaga cattatggtg acgatataaa accggaagag atgccaaagc
    17821 tcccagatga gcgacattat ggtgatgaca tcaggaagcc gaaaccggag gatactccaa
    17881 agccacctaa tgaaagcggt caaggtaatg acttaaaaga agatttggag cttaaaaagc
    17941 aacgtcgaga gcttacagag cagcttcgtg ctttaaaaac tattgaggaa gttttagagt
    18001 tcctgagaaa accaattcct ggatttgtaa cagatgaaga ttggaatttc ttagtatcat
    18061 ttgtagaaaa aggcccagaa aataaaactt ttgaagtaga taaattaaaa ttactagaaa
    18121 tcttctcaac ctcacaaggt catagagttt ggttaggtta ccttattctg gaaga
//
LOCUS       DARYLD010000043        17854 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYLD010000043 DARYLD010000000
VERSION     DARYLD010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17854
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(220..1320)
                     /locus_tag="TU651_001366"
     CDS             complement(220..1320)
                     /locus_tag="TU651_001366"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0897356.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TU651_001367"
     CDS             complement(1317..1673)
                     /locus_tag="TU651_001367"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL0897357.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TU651_001368"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TU651_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL0897358.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TU651_001369"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TU651_001369"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL0897359.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TU651_001370"
     CDS             complement(5753..6637)
                     /locus_tag="TU651_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL0897360.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TU651_001371"
     CDS             complement(6994..10050)
                     /locus_tag="TU651_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL0897361.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEEHWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYDSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGLYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TU651_001372"
     CDS             complement(10279..12162)
                     /locus_tag="TU651_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0897362.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TU651_001373"
     CDS             12439..13878
                     /locus_tag="TU651_001373"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL0897363.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TU651_001374"
     CDS             13883..14848
                     /locus_tag="TU651_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0897364.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
     gene            complement(15225..15730)
                     /locus_tag="TU651_001375"
                     /pseudo
     CDS             complement(15225..15730)
                     /locus_tag="TU651_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15727..17133)
                     /locus_tag="TU651_001376"
                     /pseudo
     CDS             complement(15727..17133)
                     /locus_tag="TU651_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17124..17483)
                     /locus_tag="TU651_001377"
                     /pseudo
     CDS             complement(17124..17483)
                     /locus_tag="TU651_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17495..17761)
                     /locus_tag="TU651_001378"
     CDS             complement(17495..17761)
                     /locus_tag="TU651_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL0897365.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
BASE COUNT         5023 a         4421 c         3375 g         5035 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta aagtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgtcgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaatgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtgacag actcccccta tagcaaacag
    15121 tgacccaaca aaccatcact agaagctata aggggagctt ttctatgcct aacaaaaatc
    15181 taaaatcaat aacagaaaaa cctaaagcag ttcatgcgca catactacct atctgctact
    15241 attgctctaa aagcaaccgg ctgatcggac aggttggtaa tggtgatact atagtcatga
    15301 tcttctgtca cactatattt tctcttcccc ttcaagggaa cgatgaggcc atctccatca
    15361 atagtagctc ccttgtgtcc agcttctaca ataactacac cattatcctt agtggaatcg
    15421 tatttttcaa taacctgttc tgttatagaa taccgatatc ctatcttact aagatagctg
    15481 tctgtccgtc tataaatata ttcagaccat atatcacgac cttctagctt cagtagcact
    15541 ttttcgtcgc tttctaggta taggtcagag gaatattcta tttgttcata ctttggtctc
    15601 accgcaagct ctatactctc atttggcctt agatattctt ttccttgaaa aaatagtaaa
    15661 gctcatagcg tttggagaag atgaaaacac ctaccagcaa catcattaat aacaggattt
    15721 ttcgcttcat tttgacttct tccttttcat ataaccatct atacctgctt ggatcatttg
    15781 agtatcaccc tcattgtctc catagtgacc tgatgataag ttctttaacc actttggtat
    15841 atccttatca gaaaagacct gggcaatctc agccgccgtt tttaaataag tccctgaagc
    15901 atctaaaaag cctgtaccaa cataaccata gaggtagttg ccagcatagt cgcctggcaa
    15961 ttctgattcc cactgtcttg accagacaga atagttatgg ccatgatagg tccttgactt
    16021 caaatccaag ggctgacccg tattgacaag gtcataaaat tgtttgttgt caagtattgc
    16081 agcacttaat tgacttccag ctacctgtga aaggtaggga gcattgacat tcactgatag
    16141 gatatcatct cccatcttgt tgacaatcaa acgaaaatta atacccgacg attgtaattt
    16201 tttccctagg tcttcctcaa tttcctttgc atatttatta tttttaaggt ctcactctcc
    16261 atcataattg cttctcgcct tccaatagtc atcaaaggct gttttattga gaaaatagag
    16321 gtaatcctca taggcagcta caagtcgctc tgatttttgt agtggccttt cagagctgct
    16381 tttgatggtt ttaatggtct gagtcagtat gttgtgataa tggttttgag tgtactttga
    16441 ggcattgaca gggctaatct tttgattctt caggctagtc acccagctca tatctaggcc
    16501 agcagtcgag tagctgccgt cgctgctcat gaagacctga ctgagctgtg ttgcgccctg
    16561 aatggctaac cgcaaaataa ctaagctgtc cctaaagcag tctgaggttt gagttagaaa
    16621 ccattcaagg ctttccaatt tggtcgtaac atctcgaatc cctatttcca gctggttttt
    16681 ggcatggtat agtgtagagg tatcagacca aagggtgcca tagtctccgg ttaaaagact
    16741 actgacctgc ttcataaacg attcgttttc atcaatctgt gcttggatca cttgcacttg
    16801 ccgttctctt agcctcttca gctcggttaa gtgatcacga tccagggttc cgtatctggc
    16861 aatctgagca tctgcccttt gataggtggt caactccact tggatagcat caatcgctgc
    16921 ttgtagcttt ttgatagagg gaatgatgat cgctgtaaaa agtcccctac ctgctgtata
    16981 ggctgctccc tgtagctctc ccgaatccag actagcaatg agatggtcgc aaccacttga
    17041 taacctgtcc gttatttcat tggctatttg gatattgttt gtcatggctt gaatcaaggc
    17101 ctttgactct gctgcactgt aggtcactcc catcgtaaac ggctcctttc accgataagc
    17161 tcttctttgt ccctctctag tctacgacga acccccatcg tatagattga cacgtgatcc
    17221 agatgctcat caacatagcg atccatttgt ctgatcaagt ggtcattggc ctcttgctct
    17281 gcgtactttc cagcttagtc ctcaggcata tggttcaata gggactcaag ggcaaaagag
    17341 aggtgctgac agtctgcttg aatctccgag actgcttgtt catgccgtcg tttcatcgac
    17401 aaaagatcct cctctagcca ctccagctca ttgatctgtc gggttagggc aagaaatttt
    17461 tcttcagatt cttctttgat catgacttat tcccctatct tgttgcttcc tctaggtctc
    17521 ttttctctaa tttggccgca agctgaggaa atttattagc ctgaataagg actgcctgac
    17581 taaagtcgct gacagcctgc agcagttgat tagagacctg acgtcccttt tccatacctg
    17641 caataccctt ggtcacacta aatgcaacgg actgttggtg aaccctactg gtgtctacac
    17701 ctaccaattc actaatagca gcagaagcag ccacagggct tgatgtaatg gtatcactca
    17761 tacaatttct cctttataac ccttatgtct tttattatat cacaggataa tagccattgt
    17821 gcttatagct cttacctaaa taatagcaac tgat
//
LOCUS       DARYLD010000044        17660 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYLD010000044 DARYLD010000000
VERSION     DARYLD010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17660
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            101..1351
                     /locus_tag="TU651_001379"
     CDS             101..1351
                     /locus_tag="TU651_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL0897366.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1460..2341
                     /gene="truB"
                     /locus_tag="TU651_001380"
     CDS             1460..2341
                     /gene="truB"
                     /locus_tag="TU651_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL0897367.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2355..3287
                     /locus_tag="TU651_001381"
     CDS             2355..3287
                     /locus_tag="TU651_001381"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL0897368.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3330..3734
                     /locus_tag="TU651_001382"
     CDS             3330..3734
                     /locus_tag="TU651_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL0897369.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3736..4014
                     /locus_tag="TU651_001383"
     CDS             3736..4014
                     /locus_tag="TU651_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL0897370.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            4004..4780
                     /locus_tag="TU651_001384"
     CDS             4004..4780
                     /locus_tag="TU651_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL0897371.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            4797..6104
                     /locus_tag="TU651_001385"
     CDS             4797..6104
                     /locus_tag="TU651_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL0897372.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKGLRF"
     gene            6242..7108
                     /locus_tag="TU651_001386"
     CDS             6242..7108
                     /locus_tag="TU651_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL0897373.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            7119..8054
                     /gene="pstC"
                     /locus_tag="TU651_001387"
     CDS             7119..8054
                     /gene="pstC"
                     /locus_tag="TU651_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0897374.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            8044..8931
                     /gene="pstA"
                     /locus_tag="TU651_001388"
     CDS             8044..8931
                     /gene="pstA"
                     /locus_tag="TU651_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0897375.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            8948..9751
                     /gene="pstB"
                     /locus_tag="TU651_001389"
     CDS             8948..9751
                     /gene="pstB"
                     /locus_tag="TU651_001389"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0897376.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            9765..10523
                     /gene="pstB"
                     /locus_tag="TU651_001390"
     CDS             9765..10523
                     /gene="pstB"
                     /locus_tag="TU651_001390"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0897377.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            10594..11247
                     /gene="phoU"
                     /locus_tag="TU651_001391"
     CDS             10594..11247
                     /gene="phoU"
                     /locus_tag="TU651_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL0897378.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            11481..14018
                     /locus_tag="TU651_001392"
     CDS             11481..14018
                     /locus_tag="TU651_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL0897379.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            14437..15111
                     /locus_tag="TU651_001393"
     CDS             14437..15111
                     /locus_tag="TU651_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897380.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKEFDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            15104..16414
                     /locus_tag="TU651_001394"
     CDS             15104..16414
                     /locus_tag="TU651_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL0897381.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVGQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            16799..17218
                     /locus_tag="TU651_001395"
     CDS             16799..17218
                     /locus_tag="TU651_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897382.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            17215..>17660
                     /locus_tag="TU651_001396"
     CDS             17215..>17660
                     /locus_tag="TU651_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897383.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT         5303 a         3236 c         3953 g         5168 t
ORIGIN      
        1 ttacttgttt ttaagtgata aagtcgggag tctggaaaaa tcattttcta ggcttttttt
       61 gctataatgg cagtgagata attgcaagaa tggagaaatc atgaaagaac taaaatgtcc
      121 tcattgccat accttattta cggtcaatga gtctgactat agtcagattt tagcacaggt
      181 acgaggtcaa gagtttgaca aggagttggc acagcgctta gaaagtgaga tgaagctgca
      241 agaagcaagg gccaataacc gcttccaaga ggtgcttact aaaaaggagc aggctattca
      301 aagcctgacc aaccgcttgg agcgtattga gcaggaacag gcctatttga ggcaacagga
      361 gctagcccaa aaggataaag agctcctaga gcttcacaat cagctagata agctagagct
      421 tgagcagcaa tcaaggctcc agtctgccct tacagttgtt gaaaaggaac gtgatcacct
      481 aaaaaatcag ctcgtgctgc aggaaaaaga aagcgaactt tctctagcct ctgtgcgcag
      541 tgattatgag gtgcagttaa aggctgtcaa tgagcaggtt gagttttaca agaattttaa
      601 agcgcagcag tcaactaaag ctattggaga gagcttagag ctgtatgccg aaaccgagtt
      661 taacaaggtt cgcagctatg cctttccaaa tgccagtttt accaaggaca atcaagtgtc
      721 tcatcgaggc tcaaagggtg attatattta ccgagagcta gacaataatg gtgttgaaat
      781 tctctcaatc atgtttgaaa tgaaaaatga ggttgacacg accaagacca agcataaaaa
      841 tagtgatttc tttaaggaat tagataagga tcgccgggaa aagaattgtg aatatgctgt
      901 tcttgttacc atgcttgaag cagacaatga ttattacaat gcaggaattg ttgatgtcag
      961 tcatgactat gacaaaatgt atgtggttcg gcctcagctc tttattcatc tcatcggatt
     1021 gctgcgtaac gctgctctta atagcttaaa atataagcaa gaactggcgc ttgtcaggga
     1081 gcagcacatt gatattacac attttgagga ggacctagag cattttaagc atgcttttgc
     1141 taaaaactac cagtctgcaa gcaataactt taaaaaagcc gttgatgaaa ttgataagtc
     1201 catcaagcgt atggaggagg tcaagcgctt tctaacaact agcgaaaatc agctgcgttt
     1261 agccaataac aagctagatg atgtctctgt caaaaaacta accagaaata atccaaccat
     1321 gcgcgataag tttcaagcaa tcaagcccta ggattatctc agtcaggctt attgatagag
     1381 gctttgttgc ttgtcaaaag ccttgtgaaa tggttataat agataggcta atgatcaaaa
     1441 caataaacga aagtaacaca tgataaacgg aataatcaat ttaaaaaaag aagcaggcat
     1501 gacatcacat gacgctgttt ttaagcttag aaagctatta caagaaaaaa agattgggca
     1561 tggagggacg cttgatcctg acgtggtcgg tgttttgcct atagcagtgg ggaaggcaac
     1621 gcgagttatt gaatacatga cagaagcagg taaaacctat gagggagagg ttactcttgg
     1681 ctattcaacg acaacagagg atgctagtgg agagattgtt gaccaaacag tagtgccctt
     1741 gagtttgact gaagcgatgg ttgatgaggc aatgacacaa tttattggtc aaatgactca
     1801 gattccaccg atgtattctg cggttaaggt taatgggcgc aagctttatg attatgcacg
     1861 agctggtgaa gcagtcgagc gccctaaaag acaggtaacg attgaccagt ttgagcggac
     1921 aagtcccttg acctttgcag gtggtctttg ccgatttagc tttagggtga gctgtagcaa
     1981 ggggacttat attaggacct tggcggttga tctaggaaga atgcttggct atgcaagtca
     2041 tatgtcttgg ctggttcgga cagcttcttc gggtttaagt ttggatcagt cctatacctt
     2101 gtcagagatt gctgagctgc tggataaaaa ggacatgagc tttttattgc ctattgaata
     2161 tggtgttagt gatttagcca gagtagtcgt taatgactgg gagctgagag agctttcctt
     2221 tggtagaaaa atcgctctat catgtgagga aaatctgtta gcggcttttt atcaggacag
     2281 cttgatcgct attttagaaa agcaagaagg gctttacaag ccaagaaagg tttttattta
     2341 gagaagattg atatatggat atacaacaca ttaaaagcta tcaggagatt gatgaatcag
     2401 ctgataccgt tttagtctta ggctactttg atggtctgca ccgaggtcac aaggctctat
     2461 ttgataaggc aaaggaaata tcacgtcagg aaagcctaaa aatagtcacc ttgaccttcc
     2521 atgagtcccc tcagctggcc tttacacgct tttctcctga ttttttacga cacattacct
     2581 atccagaaaa aaggtatgaa aaatttgctg agtatggtgt tgataagctt tatttgcttg
     2641 attttaccac gtcattttca aaactatcct ctgatgattt cattgaccac tatattgggc
     2701 gtttaagggt aaggcatatc gttgtaggct ttgattatca ctttgggtgt gatcacgcag
     2761 atagtcatta cttagctaaa cggataaaag gaaccgttta tagcatttca gaggtcaaag
     2821 aagaccagat caaaatctca tcaacacgta tcagaagtct gattacagca ggagatgtcg
     2881 ctaaggctaa tcagctgctt ggctatgagc tttcaacaag aggaatggtt gtgcatggtg
     2941 atgcgcgtgg gcgaaccatt ggttttccga ctgccaatct tgcacctatt gataggacct
     3001 atctgccagc tgatggtgtt tacgtgacag atgtgctggt tagaggaaag cgctatcggt
     3061 ctatgacgag tatcggcaag aacattacct ttggtggtaa agagctgcga ttagaggcaa
     3121 atatttttga ttttaatgag gacatttatg gagaaactct tgaaattatt tggctagata
     3181 ggattcgtga gatgaataaa tttagtgatg ttagcacctt tatcagccaa ctaaagcagg
     3241 ataaagaagc tgccataaat tggaaaaaag atagccaagg ctattaaatt tttgtataat
     3301 aaggtaagca caattaacag aggaaaagta tgattacctt atttctatca ccaagctgta
     3361 ctagctgccg taaggccaga gcctggctca ccaagcatga cgttgacttt caagagcata
     3421 atattattac cagcccactt agtcgtgagg agctgttagc gatcctatcc tttactgaaa
     3481 atggaacaga ggatattatt tcaacacgat caaaggtttt tcaaaaattg gatattgata
     3541 ttgatgagct gtctatcatg gatttgattg atttgatcgc aaagaaccct agccttcttc
     3601 gtaggccaat cattatggat agtaagcgca tgcaaattgg ctttaatgaa gatgagatta
     3661 gggcattttt gccaagggat tatcgtaagc aagagctgcg ccaagcaacc ataaaggcag
     3721 aaatcgaggg ataacatgtc agatcattat cattacccac ttgatgtaag ctggagcact
     3781 gaagagataa catcagtgct tcatttttta aatcaggtag agttagccta tgaggctaag
     3841 gtaggagcag aggagctact caaaagctat gctgcctaca aggagattgt aagaagcaaa
     3901 tcacaggaaa agcagattga ccgcgaattc caacaagcca gtggctattc aacctatcaa
     3961 gctgtcaaaa aagccagaga aattgagaaa ggattctttt cccttggaag ataaatacgc
     4021 atttgctaaa acgatcatca aagaggctgg ccttctgatt aaggatagaa tgaaagatag
     4081 cttagccatt gaaatcaaga cgcagcatga tgatttagtg accaatgtag atcaagagac
     4141 gcaggatttc ttaattgcta aaatcaaaca ggcctatcct agtgaccata tgattgctga
     4201 ggagggcggt atctgtcatg ctattacaga tggcaaggtt tgggtgctgg atcctattga
     4261 tggtacggtg aattttattg tacagaaagc caattttgcg atcatgatgg cttattatga
     4321 gaatggcgtc ggaaaattta gtctcattta tgatgtcatg gcagatcagc ttttttcagg
     4381 tggaggagat tttgctgtta ctttaaatga tcaagtccta gcatcttatc aggataagcc
     4441 gcttgatcgt agcttaattg gctgcaatgc aggtatgctt tcaaggaacg attacaacct
     4501 gcaccagttg attgatcaaa ccctaggagt gagggtttat ggcggtgcag gcatttgcat
     4561 gactaaggtg ttaaggcagc agctaatggc ttatttctct tatattcaac cttgggatta
     4621 tgcagcggca gccattatgg gcgaaagcct tggctatgtc ctgttgacct tggagggaaa
     4681 gcagccagac tttcagtcta gacagaaggt gatgtttgtt cccaagtcta aactagccac
     4741 cattcaatct ctgctgaaaa caaacgagaa tacccaataa gattaaaatg aaaagcatgc
     4801 aattaccaaa cgattttatt gaaaaatacc aacagctgct aggttcagaa gcaaaagctt
     4861 tttttgagag ctttgatcag cctgccatca gtgcctacag gataaatccc ttaaagcacc
     4921 aatcggtctg ccttgatcct cctattcctg atacaccatg gggttactac ggcagggtat
     4981 caggaaagtc tcctaaccac gtgtcaggtg tggtgtattc ccaagagcct gctgctcaaa
     5041 tggttgctca ggtggcctca cctgccaagg gaactagagt gttggatttg gcagcagcgc
     5101 caggtggcaa gtcaactcag ttacttgcct atctagagaa tacaggactt ttagtgagta
     5161 atgagatttc gaccaaacgc agcaaggcct tagttgaaaa tatagagcgc tttggtgcta
     5221 gaaatgttat tgtgacaaat gagtcagctg acagactggc tgctgttttt ccagaatatt
     5281 ttgacactat tgtctttgac gggccttgct ctggtgaggg catgtttcgc aaggatccaa
     5341 atgctgttag ctattggcac aaggattacc cagcagcatg tgctagcctg caaagatcca
     5401 ttttagcaga ggcgatacct atgctaaagc caggtggtca gctgatttat tcgacctgca
     5461 cctggtcgcc tgaagaaaat gaagaggttg ttcgctggct actagaaagt tatgattttc
     5521 ttgagctgga gcatatccct aagatcaatg gtatggcaga ggggatcggt atgccacagg
     5581 cagctagaat gtaccctcat cgctttaaag gagagggaca gtttgttgct aagttaaagg
     5641 atactagatc aacgatttcc tcttcaagct acaaatctcc aaggtctaac ctcactcaag
     5701 agcagctgag gctgtggcag gattttgaaa aaaatcattt gaacataacc ttgtctggcc
     5761 tattacaggt ctttggtgat cgtttgtact tgttaccaga tggcttaccc tgtcttcgat
     5821 cgcttaaaat agcaagaaat ggtctggaat taggcacttt taagaaaaaa cgctttgagc
     5881 cttcctatgc tctgggcttg gcattaagac ctgaagaggt cagcttatct gttgagatta
     5941 acgaagagga ctttgtcaca tacgcctcag gaaataccat taccttacca gaatcttatg
     6001 ctacagattg gtatcagctg gtcattaacg gaaatggtct gggctttgct aaaatagttg
     6061 gtcgcaccct taaaaatagc ttccctaagg gcttacgttt ttaaggaatg gcataccatt
     6121 aaatttttat aaatttaaat aaaacttctt ccaaagcatt gttagatatg ttaatataaa
     6181 gaatatgctg aagcttaatt cttcgctata aacctttatt tttatgaata ggaatagaat
     6241 aatgaaatcg aaaaagaaat tctttttgtt aagtctttta gccttgtcgg ctttcttttt
     6301 gtcagcctgc tcaagctgga ttgataaggg agaatccata acagcggtag gctcaacagc
     6361 attacagccc ttagtagaag ccgcagctga tgagtttgga agcaataacc tcggaaaatc
     6421 tgttaatgtt caaggaggcg gctctggcac tggcttatca caggtgcagt caggtgctgt
     6481 tcaggtaggc aatagtgatg tctttgcaga agaaaaggac gggattgatg ctgctaagct
     6541 tgttgatcac caggttgccg tagcaggact tgctgtcatt gccaatccta aggtcaaggt
     6601 atctaatctc acaagcaagc agctacaaaa gattttctca ggtgaatata ccaactggaa
     6661 gcaggttggt ggacaggatc ttgctatttc agtgattaat cgagcggcaa gctcaggctc
     6721 acgtgctacc tttgatagtg tcatcatgaa gggtgttact gctaagcaaa gtcaagagca
     6781 ggattctaac ggtatggtta aatcaattgt gtctcagaca ccgggggcca tttcttactt
     6841 atcctttgcc tatgtggatt cgtctgtaaa atcattacga ttgaatggct ttaaggccaa
     6901 tgccaaaaat gtagcaacca atgattggcc catctggtcc tatgagcata tgtataccaa
     6961 aggcaagcca gacggcttaa ccaaggaatt tttggattat gtgctatcag atgaggtcca
     7021 aaaaaccatt gtgacacata tgggttatat tgctatcact gatatgaagg tcgtcaaatc
     7081 ctatgatgga aaagttacag ataaataatg ggggaattat gaaaaatcag gaattagcta
     7141 agcaattagc ctcaccatca aaaaattcac gacttgaagc atttggtcgt acgattacct
     7201 ttttttgcct cgccttaatt gtttttatcg ttgcaatgat tttacttttt gtggctcaaa
     7261 agggcttgtc tacctttttt gtaaacaagg ttaatctttt tgatttccta tttggtacag
     7321 agtggcagcc tagcgttaaa aatgctgccg gtgttcctta tcttggagct cttccgatga
     7381 ttgctggatc gtttttagtc acgattttat cagccttggt ggcaacacca tttgccattg
     7441 gggcagcagt atttatgact gaaatttcac ccaagtacgg ggcaaaacta ttacagccag
     7501 cagttgaatt gcttgtaggt atcccgtcag ttgtttatgg ctttattggc ttgcaggttg
     7561 ttgttccttt tattcgttct atttttggtg gaacaggctt tggtatccta tcaggggtct
     7621 gtgtcttgtt tgtcatgatt ttaccgacgg ttacctttat gacaacagat agtctgcgcg
     7681 ctgttcctcg tcattatcgt gaggcttcta tggctatggg ggctacacgt tggcaaacca
     7741 tttggcgagt ggttttaaat gcggctcgtc ctggtatttt tactgctgtt atttttggta
     7801 tggctagagc ctttggtgag gccttagcca ttcaaatggt tgtgggaaat tcagcagtca
     7861 tgccggcttc actaaccact ccagcggcta cattgacctc tgtattgact atgggaattg
     7921 gtaatacagt tatgggaact gttcaaaata atgtgctatg gtcattagcc cttgtcttat
     7981 tgctgatgag tctagctttt aattcccttg tcaaattaat tacgaaagag agaaagagaa
     8041 attatgaacg ctaaaaaggt tgataaagta gcaactggta gcttgtatac tattgctgga
     8101 attattgtag ctattttagc ttccctaatt ctgtttattc ttgtgcgtgg cctacctcac
     8161 atcagctggt cgtttttaac agggaaatca tcgtcctatg aagctggtgg aggtattggg
     8221 attcagcttt ataattcatt tttcttgctg gtagtaacct tgattatttc cattccccta
     8281 tcaacaggtg ctggcattta tttggccgaa tacgctaaaa aaggacctgt gacaaatgtg
     8341 attagaacct gtattgaaat cctatcctca ttgccatctg ttgtggttgg attgtttggc
     8401 taccttattt ttgttgtaca gtttgaatat ggcttttcta ttatatcagg tgcccttgct
     8461 ttgacggtat ttaatcttcc gcaaatgaca agaaacgttg aggatagctt gctgcatgtg
     8521 catcatactc aaagagaggc agggctagcc cttgggcttt cacgctggga aacggttttt
     8581 catgtggtta ttccagaggc cttgccaagt attgtgacag gtattgtttt ggcttcaggt
     8641 cgtatctttg gtgaagcagc tgctcttatc tatactgcgg gtcagtctgc cccagcgctt
     8701 gattggtcaa attggaaccc tttgagcgtg acaagcccta tttcaatttt ccgtcaatct
     8761 gaaaccctag ctgttcatat ttggaaggtc aatagtgaag ggacaatccc tgatgcaaca
     8821 cttgtttctg ctggtagtgc agcggtgttg ttgattttta tccttatttt caatctatca
     8881 gctcgcttta ttggcaagcg tattcatgct aagatgacag cagcaaaata agacattgga
     8941 gagattcatg acagaatata attggaacga acgtcatatc attacatttc cagaagaaac
     9001 gattgcccta gctactaagg atctgcatgt ttattatggt agcaaggagg caatcaaggg
     9061 gattgatatg caattcgaaa aaaataaaat tacagcccta attggaccct caggctgtgg
     9121 caagtcaacc tatctgcgca gcctcaatcg catgaatgac accattgata ttgctagagt
     9181 aacaggtgaa attttgtatc aaggcattga tgtcaatcga aaggacatga atgtgtatga
     9241 aatccgtaag cacctaggaa tggtctttca aaggccaaat ccatttgcca agtctattta
     9301 taaaaacatc acctttgctc atgaaagagc aggagtgaga gataaaaggg ttttagatga
     9361 gattgtcgaa acctccctca agcaggctgc actatgggat caggtcaagg acgatcttca
     9421 taaatcagcc tttacccttt caggaggtca gcagcagcgc ttgtgtattg ctagggctat
     9481 ttcggttaag ccggatatct tgttgatgga cgaaccagct tcagcccttg atcctattgc
     9541 aaccatgcag ctagaagaaa ccatgtttga gttgaagaag gattacacca ttattatcgt
     9601 tactcataac atgcagcagg ccgctagagc aagtgattac actgctttct tctatttggg
     9661 tgacttaatt gaatacgata aaacgcgtaa cattttccaa aacgctacct gtcagtccac
     9721 aaatgattac gtctcagggc actttggtta gaaagaagga tatgatggca gaacctattt
     9781 tacaaatcag agatctttct gtttactata ataaaaagaa aaccttaaag gacgtgtcct
     9841 tagattttta cccaaatgaa atcacagcac tcattggccc ttcagggtct gggaaatcaa
     9901 cacttttgcg ttccatcaat cgcatgaatg acctgaatcc agaggtaacc attacggggt
     9961 caatcgttta taatggacat aacatttaca gtccaagaac agacactgtt gatttgcgaa
    10021 aagaaattgg tatggtcttt cagcagccca atccctttcc aatgtctatc tatgaaaacg
    10081 ttgtctatgg cttgcgccta aagggcatta gagataaggc tgttttagat cacgctgttg
    10141 aatcctctct caaaggagcc tccatctgga gtgaggtcaa ggataggctt catgattcag
    10201 ctgttggact atcaggaggt caacagcagc gtgtctgcat agcaagggtt ctggcaacca
    10261 gccctaaaat cattttgtta gatgagccaa catcggcttt agatcccatt tcagccggca
    10321 aaatcgaaga gaccctgttc tcactaaaaa aggattatac gatggttatc gttacccgct
    10381 ccatgcagca ggcctcgcgc ttgtcagacc ggacaggctt cttcttagag ggagaccttc
    10441 ttgagtttgg tcctactaag gcaatgttta tgaaccctaa gaggaaggaa acagaagatt
    10501 atatttcggg taaatttggc taagggatct tgtttgtagt ctaggtatcc gctctgttta
    10561 ggataataaa tgaatcaata gaaagaaaaa atgatgttaa gaactaaatt tgaagaagaa
    10621 ttagacaagc tacacaatca gttttactct atgggaacag aagtcttgtc tcaaatcaat
    10681 aaaaccgttc gtgcctttgt cagtcatgac cgcgaattgg ccaaagaggt gattgaggaa
    10741 gacgatacca tcaatggatt tgaaacaaaa ttagaaaaaa agtctcttga aattatcgcc
    10801 ttacagcagc ctgtttcaaa cgatttgcga acagttatta ctgttttgaa ggcctcaagt
    10861 gatattgagc gtatgggaga tcacgctgcc tctatcgcta aagcaaccat tcgcatgaaa
    10921 ggagaagagc gtatcccgat tgttgaggag catatcaact tgatggggaa ggcagtcaag
    10981 cagatggttg aagaggcgct aaatgcttat attaatgcag atgatgccaa ggcctatgaa
    11041 attgctgctt cagacgaaat cattgataat tatttccgcg aaatccaatc tctagctgtc
    11101 gaagaaattc gcaagacacc agatgccgtc tttgctggca aggaatactt ccaggttctc
    11161 atgtatttag agcgtatcgg tgactatgct cgtaatattt gtgaatggat tgtctattta
    11221 aaaactggaa aaattattga attataagaa agtatggtat aatgggggct gggtgaactt
    11281 ctcagttcct cgttttatta tagcgattaa aaggttttag aggctggagc ttcagctgag
    11341 ctgactatca gctgtcaagc ttctagacaa aatgaaagat aacaataagc tagtcgtcta
    11401 agggactaga cggcaggatt gattatatta agaatgtgac cttgtcccat cactaattta
    11461 atgacatatt aaggagttgt atgaaaaaag tagaacatct tattgaaaag tttattcctg
    11521 aaaattataa tattttctta gacattaatc gcagcacaaa aaccttcaca ggtaatgttg
    11581 caatcaatgg tgaagcatta gataatcaag tgtcatttca ccaaaaggac ttggcaatca
    11641 atgccatttt acttgacaat gaagctgtta gctatcatgt tgacgatgac aatgagcttg
    11701 tgcgtgttga gctgccagag actggtatga tgacgcttgt cattgaattt tcaggtaata
    11761 ttactgacaa tatgactggt atttacccgt cctattacac aaaagatggt gaaaaacagg
    11821 aggttatttc aacgcagttt gaaagccatt ttgcgcgtga ggcctttcca tgtattgacg
    11881 agcctgaagc aaaggctacc tttgacttaa gcttgacatt tgaccaagca gagggcgaga
    11941 ttgctctatc aaatatgcct gaggtcaatg ctgagcgccg caaggagacc ggtctttgga
    12001 cctttgagac aactcctaga atgtcttctt atctgctggc ctttgcctta ggagacttgc
    12061 atggcaaaac aacaaaaagt aaaaacggga caacagttgg tgtttatgca accaaggctc
    12121 acccactgac ctcgctagat ttttcattgg atattgctgt acgtgtcatt gatttttacg
    12181 aagactactt tggggttcgc tatcctattc cgcaatctct aaatattgct cttcctgatt
    12241 tttcatctgg agcgatggaa aactggggct tgattaccta tcgtgaaatt tacctgttgg
    12301 ttgatggcaa ttcaacagcc cgcagcagac aaaatgttgc tcttgttgtg gcacacgaga
    12361 ttgcccatca atggtttggt aatcttgtaa ccatgaaatg gtgggacgat ctttggctaa
    12421 atgaaagctt tgccaatatg atggaatatg tagccatcaa tgctattgag ccgtcatggc
    12481 gtatttttga ggatttccaa acaacaggtg tgccgctggc tcttaagcgt gatgcaacag
    12541 acggtgttca atcagtccat gttgctgtta atcacccaga tgagattaat accctgtttg
    12601 atccagctat tgtctatgcc aaaggtagcc gcttaatgca tatgcttcgt cgctggattg
    12661 gcgataagga ttttgcggca ggtctgcgcc tttactttga aaagcatcaa taccgtaata
    12721 ctgtaggacg tgatttgtgg caggctcttt cagaagcttc tggtaaagat gttgctgcgt
    12781 ttatggacgc ttggctagag cagccaggct atcctgtctt aacggccaga gttgacaatg
    12841 atcagttgat tctcagccaa aagcagttct ttattggtga ggcaagcgac caaaagagac
    12901 tatggccaat tccactaaat gcgaactgga aaggtcttcc tgacgtactg acagaggagt
    12961 ccatcgttat ttcaggcttt agtcaattag ccgcccaaaa taaaggaaca cttcgcttta
    13021 atacagaaaa tacagcgcat tacattacag attatcaggg acagctcttt catagcttag
    13081 ttgatgattt gaagcatctt gacaacacct ctgcccttca agtgattcaa gagcgccgct
    13141 tgctggctga tagcggtctg atttcttatg cagagctggt tgacttaatc gctcagctag
    13201 atgacaaaaa atcctatatg gttgctgcag ctgttcagca ggttattaga ggcttagagc
    13261 agttcattga tgaaggaacc tcagcagagc agtccttcaa tcgattgatt tcttctattt
    13321 tccaagagga cttcaggcag cttggatttg aaaagagggc aaatgaatct gatgaagatg
    13381 aaatggttcg tcaaattgct ttacatcacc tgttggttgg aggcaatcgt gatgtgatca
    13441 agcaggccaa gactatcttt gaagcttatg caaatcgtat cgaagccatt ccagcagcca
    13501 ttcgccgctc ggtattggtg agtcagatca agtattttga aatagctgac ttggttgatg
    13561 cttattttga tgcttatgtt gcaaccaagg acaacaatct tcgagctgat ttgagcgccg
    13621 ccttagcaac aacagctaat ccatcaactc ttaagcgcat tcagtacagc ttaaaggata
    13681 aggatattat taagccacag gacttagcag cttggtacag ctttttgctt gatcaggcct
    13741 ctgcacaaga aagcatttgg cgttgggcta gagaaaattg gaagtggatt aaggcttcac
    13801 tgggtggtga tatgagcttt gacaagttta ttatttaccc tgctaaccat tttaaaacag
    13861 cagagcgttt agctgaatat aaggccttct ttgagccaca gcttgatgat atggcgatta
    13921 gtcgcaatat ttcgatgggg ataaatgaaa tttcagctcg agttgccctc attgatagtg
    13981 aaaaggaagc tatcgctaat gctttaagtc agtactaatg atatcacaaa ggagctgggg
    14041 accatcctca actcctttat tggtgtcaaa gctactatct ttaagtaaca tttagatcaa
    14101 agggtaattg ctgtagctta gtggcactgc ctgtcagctt ttggcaaatg aggaggcttc
    14161 aatcataagc agtggttaat cttagcgccg taaattacta gttgatcaga gtcagagctt
    14221 aggacggata ggtcatagag acaattcttt gtctgtcagt tttataactt aagtaggtct
    14281 ccagactaac tgtatgctta tgacctgtca tgagcaatag tttagcaaag cttaagcttt
    14341 ttgtgttatc gttagattag agaattcatt tagtaaggta atccctaaag actacttgag
    14401 cgaggctgtt agtctttaga gaattgaggt atcataatga taaaactatt attagtagaa
    14461 gacgatttaa gcttgtcaaa ttctatcttt gattttttag atgactttgc tgatgtgacg
    14521 caggtttttg atggtgacga aggactctat gaggcagaaa gcggtattta tgatttgatt
    14581 ctgttagatt tgatgctgcc tgaaaaggat ggctttcaag tgttaaaagc cttacgtgaa
    14641 aaagacatca aaattcccgt cttgatcatg actgccaaag aaagcatcga tgacaaaggg
    14701 catggctttg agcttggtgc tgatgactat ttaaccaagc ccttttacct agaagaatta
    14761 aaaatgcgga ttcaggcctt gcttaagcgc gtaggaaagt ttaatgacaa gagccttaaa
    14821 tttggcaacc tgactgtaga tactacccgt aaagaggtac aggtcaatgg gcaggccata
    14881 gagctattag gcaaggagtt tgatttacta atctatatcc ttcaaaatca aaatgttatt
    14941 ttgccaaaat cacaaatttt tgatcgtatc tggggctttg atagtgatac cactatctct
    15001 gttgtagagg tctatgtctc taaaattcgt aagaagctta aggggacaga ctttgttaat
    15061 catcttcaaa ccttgagaag tgtaggatat atcttaaaag ctaatgaata aactaaaaaa
    15121 aggattattg tccgataatt atacgcattt ttttcatttc tttgctattt ttacaggcat
    15181 ttttgttgtc atgaccatca ttattttaca aatcatgagg tttagtgtct attccacagt
    15241 agacagcagt ctcatttcgg tcggtcaaaa tgccagcaac tatgctaata ggaccatggc
    15301 gagaatatct tccttttatt ttgatgcaga aaataacctt attcaggctc ttcctgaact
    15361 ggaagcgtca aaatcacttg gctcctccac cactaatatg gatattattt tatttagtgc
    15421 taatgggacg atattgaact cctttgacgc tttctctaat taccaaagct ttcgtttaga
    15481 caaaagccag ctcaataaca ttgtcaccac acagctgatg aatttttatg ggcaaaagga
    15541 gaaataccat accctaaccg ttaaggttca cattaaaaac tatccagcag tggcttatat
    15601 gatggcagtg gttaatgttc agcagctgga tactgctaat gagcgctatg aacagattat
    15661 tatcatggtt atgattgtct tttggttaat ttcgattttg gccagtattt atttggctaa
    15721 gtggagcaga aagccaatta tggagagcta tgccaagcaa aaaatgtttg tagaaaatgc
    15781 cagtcatgag cttaggactc ctttagcggt gctgcaaaat cgtttggaat cgctgtttag
    15841 aaagcctaac gaaaccattt tagacaatag cgagcatatt gcgtcaagcc tagatgaggt
    15901 tcgtaatatg agaatattaa caactaatct gttaaattta gccagaagtg atgatgggat
    15961 caagccgcag ctagttgatg ttgatgcagc cttttttgat actgtttttg aaaattatca
    16021 attagttgca gaagagtcag gcaagcagtt tatctcagtt aatcagatca ataggccctt
    16081 aaagacggat aaggctttgc tcaagcagct gatgaccatt ttgtttgata atgcgatcaa
    16141 atacactgat cataacggtg tggttgaggt caaggttaga acgaccgata agcatttatt
    16201 gatttctgtt attgataatg gcccagggat caaggatgat gataagaaaa agatttttga
    16261 tcgcttttac cgagtggata aggcaagggc acgccaaaaa ggagggtttg gactcggatt
    16321 ggccttagcg cagcagatcg ttacctcatt aaaaggaacg attaccgtca gtgataataa
    16381 gcctaccggc gccatctttg aagtaaaatt atagcactga gttcttgcta gcccataatc
    16441 agtatgaaaa taacagtcac tagatcaaga agtctagtga ctttttttat tgtcttcttt
    16501 ttgctgttga ccaagcagtt gacaagaaaa ttccaataga tagtttaaag ccaataaaac
    16561 cattattagg cttgcattac aggcaggtat caaacaaaga tatagaaaaa tataccataa
    16621 aaaatctcat aaaagtgtca aaatggtaaa aaattgccaa caatatgtcg atattatacc
    16681 attattatag tataatattt ataatcgtat cataatatta aaatatctgg tgtctagctg
    16741 tttttgtaaa agcaaaaaac ttgcaacacc ttatgataaa gcataaagga atacaagcat
    16801 gatagtctac ctaaagcaac acaaaaatta ctggaaatta gtcagcatag ccgctttaat
    16861 cattatttta ggaggaatac taacaatgaa ttggcttaat ggcgaagagc taaaaaagaa
    16921 aaagtacaga caagagcagg atagggtagt gaaatacata ggagagcata tagagctatg
    16981 taatggtcag cctataacaa aaattgagtt tatagaattt cagttagaaa ctgcaaccac
    17041 cggaacttgg tcaataacaa caattgttaa tgagaaatat ctgattcatt tttcagaaga
    17101 tagattaggt gaagaaatac ggacttccta ttattctcca aaagaattta agcaatacag
    17161 tgaaaagatg aggaataata tgactaatgt tgaaacaatt tattacgagg agaaatgatg
    17221 attgatagag attataaaaa tatttcagag gatgtgtata aggttgattc tggtaaagaa
    17281 agagatccga ttcaagaagg atatccggtt gccaatggaa aataccgcgt tcttgaagcc
    17341 gaagataacc ccgacaatgg tatgcaggct atggctgttg tgccaataaa agatggcaaa
    17401 gaggatagaa gtcatatcgt cattgcctat gccgggacaa atagcagtga tatacgcgat
    17461 attgacaccg atattcaatc cgttgttttt ggagatgatc aatacctgtg tacccatgag
    17521 gagcctgatt cttttaaagt agtcaagagt cagctaagta ctgctaaagc cttttccgac
    17581 tacattagga caagctaccc taacgctgcc atctcctata ccggacactc tctgggaggc
    17641 tatctggcac tcatcacagc
//
LOCUS       DARYLD010000045        17574 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYLD010000045 DARYLD010000000
VERSION     DARYLD010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17574
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            67..642
                     /locus_tag="TU651_001397"
     CDS             67..642
                     /locus_tag="TU651_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL0897384.1"
                     /translation="MKKVINTILLAACFLFFLGNFTTNVLAEGINDKIENGTESDISF
                     QNGELLKNYLILEGERVYFDYDRATQDKVSDDVLEMGMLVEAISKDYSEKTFTPDKYF
                     KASWPIHGNYCGPGHNGNNFTLPVVDVLDQGCQNHDSCYKWGAGIGANCECNRQLVNY
                     IKVYRRWMPANVLGVADAIRVYFETVGSIGC"
     gene            991..1173
                     /locus_tag="TU651_001398"
     CDS             991..1173
                     /locus_tag="TU651_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0897385.1"
                     /translation="MLTYDEFKQAVDNGYITGDTVTIVRKNGQILDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            1371..1760
                     /locus_tag="TU651_001399"
     CDS             1371..1760
                     /locus_tag="TU651_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL0897386.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            1757..2968
                     /locus_tag="TU651_001400"
     CDS             1757..2968
                     /locus_tag="TU651_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL0897387.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2981..4327
                     /gene="asnS"
                     /locus_tag="TU651_001401"
     CDS             2981..4327
                     /gene="asnS"
                     /locus_tag="TU651_001401"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL0897388.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            4629..5669
                     /locus_tag="TU651_001402"
     CDS             4629..5669
                     /locus_tag="TU651_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0897389.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEVGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERGEQGPKGERGEQGPKGDRGEQGPKGERGEQGP
                     KGDRGEQGPKGDRGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKKEP
                     EKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGFIA
                     SAGLLVFKRKKN"
     gene            6195..7085
                     /gene="rapZ"
                     /locus_tag="TU651_001403"
     CDS             6195..7085
                     /gene="rapZ"
                     /locus_tag="TU651_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL0897390.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            7082..8059
                     /locus_tag="TU651_001404"
     CDS             7082..8059
                     /locus_tag="TU651_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL0897391.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            8056..8967
                     /gene="whiA"
                     /locus_tag="TU651_001405"
     CDS             8056..8967
                     /gene="whiA"
                     /locus_tag="TU651_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL0897392.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            9327..10724
                     /locus_tag="TU651_001406"
     CDS             9327..10724
                     /locus_tag="TU651_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL0897393.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            10964..12514
                     /locus_tag="TU651_001407"
     CDS             10964..12514
                     /locus_tag="TU651_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL0897394.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
     gene            12785..13513
                     /locus_tag="TU651_001408"
     CDS             12785..13513
                     /locus_tag="TU651_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0897395.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            13525..14700
                     /locus_tag="TU651_001409"
     CDS             13525..14700
                     /locus_tag="TU651_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL0897396.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            14710..15705
                     /gene="lacD"
                     /locus_tag="TU651_001410"
     CDS             14710..15705
                     /gene="lacD"
                     /locus_tag="TU651_001410"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL0897397.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(15747..16466)
                     /locus_tag="TU651_001411"
     CDS             complement(15747..16466)
                     /locus_tag="TU651_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0897398.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            16606..>17574
                     /locus_tag="TU651_001412"
     CDS             16606..>17574
                     /locus_tag="TU651_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011922008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0897399.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQ"
BASE COUNT         5128 a         3387 c         4195 g         4864 t
ORIGIN      
        1 ggtttgttga catattgggg tagcacttaa tagtttctct gttattaaaa tagttggaga
       61 aaatttatga aaaaagtaat aaatactatt ctattagctg cttgtttttt attcttttta
      121 ggtaatttta ctacaaatgt attagctgaa gggataaatg ataaaataga aaatggcact
      181 gaaagcgata ttagcttcca aaatggtgaa ctcctaaaaa attatcttat cctagaaggt
      241 gaacgagtat actttgatta tgatagagca actcaagata aagtatcaga tgatgttcta
      301 gagatgggaa tgttagttga agctataagt aaggattatt ctgagaagac attcacccca
      361 gataaatatt ttaaagctag ttggcctatc catggtaact attgtggacc aggtcataat
      421 gggaataact ttacgttgcc agtagtagat gttttggatc aaggttgcca aaaccacgat
      481 agttgctata agtggggtgc cggtattggt gctaattgtg aatgtaaccg tcagctcgtt
      541 aattacataa aagtttatag acgatggatg ccagcgaatg tccttggcgt agccgatgct
      601 attagagtat attttgagac agtaggttct ataggatgtt aaatttcaaa aaaaacgtta
      661 gtgattattc gaagtactat attttgagta tagtgttatt atggatagga atgttctttg
      721 ttccttggga taagactcta ttcggtgttt cgatttatct gtttgttatg caaaagttat
      781 ttatagtgtt tggtttgacg gctatcttca tggcctttgt gtctaaaaaa ataaatctat
      841 ttatttgggg aatattattt attttcgcat tttggattaa tatgtttttg ttattttccg
      901 tattaccaat tttggggaat tagtttaaca aaaaagaaga gggggggttc tccctcttct
      961 tttacgaata aatagataag gaggtgcttt atgctaacat acgacgaatt taagcaggca
     1021 gttgataacg gttatatcac aggcgacaca gtcacgatcg tgcgtaaaaa cggacagatt
     1081 ttggattatg tgttgccgca tgaggaagta aggaacgggg aggttgtgac agacgaaaaa
     1141 gtggaagagg tgatgagaga attagacaaa taaaaaagac ctcgtccaga agtcggggaa
     1201 ttgtcgggga caacgtttgt aaatgtttct attccaacat aaaacatttt ttgatataat
     1261 aggaaggatc atatgcaaag gagctgaaat tggacaagca caaaaggctc aaaacagttt
     1321 tatatcaatg tgccagcttg gtcgtactgc tttgtcttgg agtgatgagc atgttttatc
     1381 ttgctgttca tgatcaattt gacaagaaat caaggttagc cgagatagca aaatcaagag
     1441 ctggtgtcat ctcaattgat catattgatt gctatcatgg cactcagagc tacctcagtc
     1501 tttttggaaa aaacaaggca ggcaatacca tcatcgtcac aatagaggag caatcagagc
     1561 agctcttgct tagtcgccct agcaatggca ttagtgctaa ggaagcacag gaaattgcct
     1621 accatgccgg agcaaggact attgaagcag tgacatttgg gattgaaaac cacaagagga
     1681 tttgggaggt ggctgctcaa aacggctact atctgattga tttcaaaacc gcaaaagtga
     1741 tcaaaaagga ggttttatga ccaagctatc aaggcgcgtg ttagcaatgg aagaaagcgt
     1801 caccctagca gcaggtgcta gagcaaaggc actaaaggct cagggacgcg atattttaag
     1861 cctaactctg ggagagccag attttataac accgcagcat atccaagaaa aggccattga
     1921 ggccatcacc actggtaagg caagctttta cactgttgct tcggggttgc cagagctcaa
     1981 ggacgccatt gctgattaca tggcacgatc ctatggttat attcctacca gacaggagat
     2041 tgtagtgggg acaggcgcca aatacgtttt gtatgccttt ttcatggctg ttttaaatcc
     2101 tggtgatcag gtgttgattc cgactcctta ttgggtttct tatgctgatc agattaaaat
     2161 ggtagacggg gtaccggtct ttgtacaggg cttggaggaa aatcaattta aggtcacagt
     2221 agagcagcta gaggctgcca gaactgatca aacaaaggtt gttttgatca attctccgtc
     2281 caatccaact ggcatgattt acagccgaca ggagcttgaa gccattggca attgggctgt
     2341 tcagcatgat attctgatcc tggcagatga tatctatggt gcattggtct acaatggcaa
     2401 tcaatttact ccaatatcag ccttatcaga ggctattcgt agacagacca ttactgtaaa
     2461 tggcgttgcc aagagctatg cgatgacagg ctggcgtttg ggctttgcgg tcggagacac
     2521 tgatattatc gctgctatgg gtaagattat cgggcaaacc acctctaatg tgacaacagc
     2581 gtcccaatat gcagcgattg aggcctttgg cggtgaccaa acgtcagttg aggagatgag
     2641 acaggccttt gaagagcgcc tcaataccat ttatcccctg ctcaatcaag ttcctggctt
     2701 tgaggctatt aagccccaag gagcctttta tttctttccc aatgtcaaaa aagctatgga
     2761 gatgaagggc tttaccgatg tgacagcctt tactgatgcg atcctagaag aggtaggact
     2821 ggctgttgtc agcggagctg gctttggtgc tccagaaaat atcaggctaa gctatgccac
     2881 tgatttggca accctaaaag aagctatcag acgactcaat cagttcatga caactgacag
     2941 cagccatgac aacaaagaga atgaatagaa aagagacatt atgaccaaaa aatacgtttc
     3001 cattatcgat gttaaagacc atgtaggaca agaagtgaca gttggtgctt gggtcgccaa
     3061 caagtcaggc aaagggaaaa tagccttttt gcaattgcgt gatggctcag cctttttcca
     3121 ggcagttgcc tttaagccaa acctgatcca agcctttggt gaggaagcag gagcagctaa
     3181 gtttgacacg attaggcatc tcagccaaga aacctctgtc ttagtaaagg gcattgtcaa
     3241 agaggacgct agatcaaaat ttggctatga gctagacatt acggacctag aggttattgg
     3301 ggattccaag gattatccaa ttactccaaa ggagcatggg acagactttc tcatggatca
     3361 ccgtcacctt tggctgcgct ctcgcaggca ggcagcaatc atgcaaatcc gtaatgccat
     3421 catctatgct tcctatgagt tttttgatca aaatggcttt atcaagtttg atagcccgat
     3481 tttatcaggc aatgctgctg agaacacaac agagctattt gagacagatt attttggcaa
     3541 tccagccttt ctcagccaat caggtcagct ataccttgaa gctggtatga tggcgcttgg
     3601 tcgcgtcttt gactttggtc cggtatttcg tgccgaaaaa tcaaaaacgc gccgccatct
     3661 gacagagttt tggatgatgg acgcagaata ccccttctta tcccatgagg aatccttaga
     3721 cctacaggaa gcctatgtta aggcgatgat tcagggtgtg cttgatcgtg ctccacaggc
     3781 attggagctt ctagagcgtg acacagagct gctgaaaaga tacattgcag agcccttcaa
     3841 gcgtgtctcc tacgacgatg cgatcagcct gcttcaggag cacagcacag atgacgatgc
     3901 cgactatgag ccaattcagc atggcgatga ctttggctca ccgcatgaaa cctggatttc
     3961 caattatttt ggggtcccaa cctttgtcat caactaccca gctagcttta aggcctttta
     4021 catgaagccg gttcccggca atgaagagcg cgtgctatgt gcggacctgc tagcaccaga
     4081 gggctacggt gagattatcg gaggctcggt tcgtgaggat aactatgaca aattgttggc
     4141 gaaaatcaag gctgaaggcc taaatcctga ggattatgac ttttaccttg accttcgcaa
     4201 atatggctca gtgccgcatg ctggttttgg acttggacta gagcgcatgg tgacctttgt
     4261 tgcaggtacc aagcacattc gtgaggctat tccatttcca cgcatgcttc atcgcttaaa
     4321 accataatga accctatcag cgtccgccat tgggcgcttt tttgctgcgc tgagcagtac
     4381 ttagagctca agcctcccag ttagacttgg cagagctgtg gctctttgct tgagctattg
     4441 taggcaaagg tatcactgga tctgaaaaca acaaaatcag acaagtgata tcaaaattaa
     4501 aaaaaaaaaa aaaacgaaac ctaggaggat cggtgagctt attagtttgg cactaatcat
     4561 cattatgcta taattgtctt cacaaataat ttagaaatag ctcatatttc tatcattaaa
     4621 ggagagagat gatgaatcgt aaaaagcata ccaaactcat tcgtcactac agtatctgct
     4681 cagcagtggc tgtcctagca gcagttagct tgggaacagg tcaggacgta caggcttcgg
     4741 aacccaatcc atatccagat gtgaggcgtt tccttgatga gaagtacgat ggagatgtgg
     4801 ataaattatc taaacaactt caaggttatt ttggtagttt aagagagtat atagagtttg
     4861 aacttaaaaa tggcaaacaa ggtcctgctg gccctcaagg cccaaagggt gataaaggag
     4921 accccggaga gccaggtcct caaggtccag tgggccccgc tggtccaaag ggtgatcgtg
     4981 gtttagacgg acgacgtggc ccagcaggtc agcaagggga agtcggccca gttggtcctc
     5041 agggtcctca aggcgagcaa gggccaaaag gcgaccgtgg cgaacaagga ccaaagggtg
     5101 aacgcggtga gcaaggacca aagggtgaac gcggtgagca agggccaaaa ggcgaccgtg
     5161 gcgaacaagg accaaagggt gaacgcggtg agcaaggacc aaagggtgaa cgcggtgagc
     5221 aagggccaaa aggcgatcgt ggcgagcaag gaccaaaggg tgaacgcggt gagcaagggc
     5281 caaaaggcga tcgtggcgag caaggaccaa agggtgatcg tggcgagcaa ggaccaaaag
     5341 gtgatcgtgg cgaacaagga ccaaagggtg atcgtggcga gcaaggacca aaaggtgaac
     5401 gcggtgagca aggaccaaaa ggcgatcgtg gcgagcaagg tccaaagaag gagccagaaa
     5461 aagacaccaa gccatcagtg ccaaaggcac cagataatat ggctgcacca aaggctccgg
     5521 agaagaagaa ccctaaagca ccggctccta agtcagctcc aaaggcatca ttgccatcaa
     5581 caggagacac tagccaatca tttgttgcag cagcccttgg ctttatcgct agcgcgggct
     5641 tgctagtctt caaaagaaag aaaaactaag ctagctaaag actgtaaaca agcctcaact
     5701 gttacagcaa gcctctttga catcttgcag ataagaggat ttcttagcga atgaagtgtg
     5761 tctaaagtca gatactctgc tggactagca gtagctgatc tccctgaaaa tcagttatgc
     5821 taaagcattg agccttagtt gcaaggctta ggtgtgacct tccaaaggaa gctgcttttg
     5881 cctgtatcac tttaggaaga tatctaaaag agacactttt ttcacgctga agctaagcta
     5941 gcttttccta tgacaaatat cctataacaa taaactccaa acaaaagaga ggtcaaatgg
     6001 tacctctctt ttacttagct ttaggattga tagattctaa aggcttcctt gtttcttgat
     6061 caagaagtcc ttactgatag agtctgtctt agccgggctt atatggtata atacctaatg
     6121 gagataagaa aagtccttaa caaatagagt ttcatctatt gttacaggag caaccaagtg
     6181 aaaggagatg ctacatgtca gataaacaaa tcaatttggt tattgttaca ggaatgagtg
     6241 gcgccggcaa aacagttgcc attcaatcat ttgaggattt ggggtatttt actgttgata
     6301 acatgccacc agctttagtg cctaaatttt tagagctgct tgagaggacc aatgaaaccc
     6361 aaaaggttgc tctggtagtg gatatgcgca gcagacgctt tttcaaggag attaactcta
     6421 tcttagatca tattgagcta aatgccaacc tcaagctacg gatcctcttt cttgatgcga
     6481 ctgatagtga gctagtgtca cgctataagg aaactagaag aagtcaccct ctggctgctg
     6541 atggtcgggt gcttgatggg attcgacgag aaagagagct gttagtcccg cttaagagca
     6601 tgagtcagca tgtggtcaat accaccgatc taaccccaag acagctgcgt aaggtgattt
     6661 cggatcagtt ttcaagcgag tcagaccaag cctcatttag aattgaggtg atgagctttg
     6721 gctttaaata tggcctcccc ttagatgcgg accttgtctt tgatgtgcgc tttttgccta
     6781 atccttatta tcaggtggcg ctaagagagc agacagggct tgatcaggct gtttttgatt
     6841 atgtgatgac tcatcaagag tcagaggcct tttataatca tttgttaggc ttgattgttc
     6901 ctattttgcc tgcttatcaa aaggaaggca aatcagtgct aaccattgct attggctgta
     6961 caggtggtca gcatagaagc gtcgcctttg cccatcgctt ggcccaagac ttgacagcag
     7021 actggccgct gcatgagagt catcgggaca tcaatcgtcg taaggaaacg gtaaatcgct
     7081 catgagaaat cctaaaataa cggtgatagg aggaggaaca ggtattcctg ttatcctaaa
     7141 aagccttcgc aaggaggcgg ttgacattac tgcggtggtc actgttgctg atgatggtgg
     7201 gtcatctggt aagctgcgca atgccatgca gcttaccccg ccaggtgatt tgcgcaacgt
     7261 cttgttggcc atgagtgaca tgcctaagtt ttatgagcgt gtgtttcagt atcgttttaa
     7321 tgaggcagat ggtgctctag ctggtcatcc tctaggcaat ttaattatcg caggtatttc
     7381 tgagatgcag ggatccacct ataacgctat tcagattttg acgaaatttt tccatatcac
     7441 cggcaagatt tttccctcaa gcgagcagcc cttgacactg catgctgtct ttaaggacgg
     7501 tcatgaggtg tcaggagaaa gctctattgc cagctaccaa ggcatgattg accatgtcta
     7561 tgtgaccaat acctacaatg atgacctgcc aaaggccagt cgtaaggtgg ttgaggccat
     7621 tctccaaagt gatatgattg tgcttggtcc tggttccttg tttacctcta ttttgcccaa
     7681 tcttgtaatt ccagagatca aagaagccct gagagtaacc aaggcagagg tggtttatat
     7741 ttgtaacatt atgacccagt acggtgagac agagcaattt tccgatgcgg atcatgttgc
     7801 ggttttaaat cagcatctgg gcagggactt aattgacact gttttggtta atgttgagca
     7861 ggtgccaaaa agctatatga attccaacca atttgacgaa tatctggtcc aagtagagca
     7921 tgactttgca ggtctgtgta agaccgcaaa gcgtatcatc tcgtctaatt ttctgcgttt
     7981 ggagaatggc ggagcctttc atgacgggca cttggttgta gaagaattaa tgaacctagt
     8041 taggataacc aagctatgag ttttacgaca actgttaaag aagaattgat tcatttatct
     8101 gcttctgatc aaacagaatt atcagcaatc atcaagctgg ctggtagcct aggcttggct
     8161 aatcagagct tgaatttgtc tatcacaact gaaaacgcta agattgctcg ctacatctat
     8221 gcgcttatcg aagacaccta tcatatcatt ccagaaatca ggtaccatca aaagaccaac
     8281 ttgaaaaaaa atcgtgtcta tacggtttat ttggataagc aggtggataa gctcttagca
     8341 gatttaaagc tggcagattc tttttttggc attgagacag gtattgagca gcaggtcatg
     8401 tcagatgatg atgctggtcg ggcctatctc aagggtgctt ttttagcggc agggactgta
     8461 agggatccag aatccggcaa gtatcagcta gagatctact ctgtctatct agaccatgct
     8521 caggatttgg cccagctcat gcacaaattc atgctagatg ccaaggttat cgagagaaaa
     8581 aatggtgcag taacctattt gcaaaaggct gaggacatca tggattttct cattattatt
     8641 ggtgccatgt cgtgtaagga ggagtttgag gctgttaagc ttttgcgtga ggcgagaaat
     8701 gacatcaatc gggccaataa tgcagagact gctaatattg ctaaaaccat caccgccagc
     8761 atgagaacca ttaataatat tatcaaaatc atggatacga ttggcttaga cagcctgcca
     8821 gttgagctgc agcagattgc ccagatgaga gtagccaacc cagactattc tcttcaacaa
     8881 atcgcagatt cgcttgactt tgccatcact aagagtgggg tcaaccatcg cctgcgaaaa
     8941 atcaataagc tggcagagga tttataaaga cagcttagcc tttttcaggc tgataaaaaa
     9001 gggggtaagg tgatacgaac aagccgcctt ttaaggcatg ccttgttgag ctttctctag
     9061 gctgttgatg gagtgatctc aaggcgcttt tgttactgtc attccaacag gctatctgat
     9121 tttgggatga cttcttacta ataagctttt ctaatggctg gctgacaacg attagcgata
     9181 tagttaaggc ttatcgtgat tcaacaagag gctttagtct cttttttgct tgtcagaatt
     9241 atttttttag gcttttctta caaatgagag gacaatgtga caatctgtgg tatgatatta
     9301 gtaatgaata caaaggagaa caaatcatgt catgcacaac tattcttgtc ggtaaaaaag
     9361 cgacctatga tggatcaaca atcgttgctc gtacagagga ttcacaaaat ggggaattta
     9421 cccctaaaaa aatgacagtt gttagaccaa aagaccaacc tagacactat caatctgtct
     9481 tgtctagctt tagcatggag ctgccggatc agccgatggc ttatacctcg gtgcctgatg
     9541 ccctaggaaa ggacggtatc tggggagaag caggtgtcaa taccctcaat gttgctatgt
     9601 cagcaactga gaccattact tcaaatgctc gcgttcttgg agcagatcct cttgtttcct
     9661 ctggtattgg agaagaggac atgctgacct tggtgcttcc ttatattcgg tctgcaagag
     9721 agggtgttct tcgtttggga gctatcctag aagcatacgg tacctatgag gctaacggtg
     9781 ttgccttttc tgatgagcat gagatttggt ggctggaaac aataggtggt catcattgga
     9841 ttgcaaggcg cgttcctgat gatgcttatg tcactaatcc caaccagttt ggccttgatc
     9901 actttgaatt taacaatcca gaggaatacc tgtgttccaa ggatttaaag gactttattg
     9961 ccaaatatca tctagatttg acctatagca acgagcattt taaccctcgc tacgcctttg
    10021 gtagccaaag agataaggat cgccattaca atacaccacg cgcttggatt atgcagcaat
    10081 actttaatcc ggagtttctg caggatccgc gcagctttga acttccttgg tgccaaagac
    10141 ctgatcgcaa ggtgaccatt gaagacgtta agtacgtgct tagcaatcat tatcaggaca
    10201 ccccttatga tccttacggc ccagagggaa cgccgactag tcgaaaatcc tttaggccga
    10261 ttggtattaa ccgtacgagt caaactgcta ttttacatat ccgtcccaac aagcctaagg
    10321 aaattgctgc cattcagtgg atggcctatg gttcgatgcc ctttaataca atcgttccgc
    10381 tattcaccca ggtcaagacc attccagatt attttgcaaa cactgttgaa aatgtttcca
    10441 cagacaattt ctattggacc aatcgcttga ttgcagccct ggctgatcct cacttcaagc
    10501 accatgaagc agatttggag gactatctcg aaaaaacaat ggccaagggt catgccatgc
    10561 tgcatgctgt tgaagcagcg ctagtaaaag gtcagccggt tgacctagaa gaggccaacc
    10621 aaggcatgag tgatgacatt caggcagata cacaggctct gctcaataag atcctctttg
    10681 atgctagcaa tctcatgacc aaccgcttta gcctaagcga ctaagtaatc tcaatagtca
    10741 aacgagctca tatcattata gatatgggct cttagcttga aaaggatagt agagcggtct
    10801 tatagtcaga ctaattaatg gtaacgatga gtccagttaa ggtaaaaaaa gagcacttag
    10861 ctaatgcaaa aaaagtaaaa aacttgcaaa agaatgatat tgtgttatac ttaaccagta
    10921 aatattaaga gctatttgcg atatgatata tagaggagga atcatgaaaa agaagtatct
    10981 tttaatgatg agtgtgctcg gtgtcttttt tgcgggacag atcagtcaag caaaacaggt
    11041 cctagcagat agtaaggtca aaattgttac caccttctat cctgtttatg aatttaccaa
    11101 aggcgttgtc ggaggtgagg gaaatgtgtc tatgctgatg aaagcaggaa cagagcctca
    11161 tgattttgag ccgtcaacaa aggacatcaa aaagatccaa gatgccgatg cctttgttta
    11221 tatggacgat aatatggaaa cttgggtccc tgatatgaag aaatcactga cttctaagaa
    11281 ggttacggtg attaagggaa caggagatat gctattggta gctggctctg gtcacagcca
    11341 cgagcatgac catgacgatg ccgataaaaa gcatgatcat gaccacgacg aggaaggaca
    11401 cagccatgct tttgacccgc acgtatggtt gtcaccttat cgcagcatca ccgttgtcga
    11461 aacaattcgt gatggtctat ctaaggccta tcctgacaag gctgaccact tcaaatctaa
    11521 tgccgctgct tatattgaaa agctcaagga attagataag gagtatagtg acgctttttc
    11581 agctgccaag caaaagagct ttgtgactca gcacgcagcc tttggttata tggcgcttga
    11641 ttatggcttg aaccaaatct caatcaatgg tgtcacacca gatacggagc cttcagctaa
    11701 gcgcattgca gagctatcaa aatacgtcaa aaaatatgac attaactaca tttattttga
    11761 agaaaatgct tcaagcaagg ttgccaaaac cctagccaag gaggctggtg tcaaatcagc
    11821 tgtccttagt ccgcttgaag gcctaactga aaaggacatg aaggccggca aggattactt
    11881 taccgttatg cgtgaaaacc tcaaaaccct acgcttaaca actgatgtag aaggaaaaga
    11941 aattcttcca gaagaggata ccactaaaac tgtttataat ggctacttta aggataagca
    12001 ggtcaaagac cgcaaattgt ctgattggtc tggtaactgg cagtctgttt acccattcct
    12061 tcaagacggt acattagatc aggtatggga ctataaggct aaaaaatcta aaggaaaaat
    12121 gaccgcagct gaatacaagg attattacac cactggctat cagacagatg tcagtcatat
    12181 caagattaat ggtaagaaaa ataccatgac ctttgttcgt aatggtgaaa ataaaacctt
    12241 tacttataag tacgtcggta aaaagatttt gacctatcca aagggcaatc gtggcgtgcg
    12301 cttcatgttt gaagctaagg agccagacgc tggtgaattt aaatatgttc agttcagtga
    12361 ccatgctatc gcaccaggta aggcggagca tttccaccta tactggggtg gtgacagcca
    12421 agaaaagctt cacaaagagc tagagcattg gccaacttac tatgatgcgg acctatcagg
    12481 tcgtgccgtt gcccaagaaa tcaatgctca ttaaccactc aaaagactag gcagttcaat
    12541 cggcctagtt ttttcttgtc ttagttgctg tataggacct aaatgctgat agctggtctt
    12601 aagatttatt tttaattttt ctaactatat ttaggttgta tttgtttgtt aataccaaat
    12661 ccattgtttt agggattata tagaattaat atgttaaata ttttaatatt tttcaaaaaa
    12721 gtattgactt ttagattgta atataatatt atttaagtgg ttataataag ttagaggtgt
    12781 tagtatgata aaggaacagc cactctactt acaaattgtt gatgtattag aggtcaaaat
    12841 tagaaatacc atgtcagcta atgataaatt gttatcagaa cgagagctaa gtgacttatt
    12901 tggtgttagt cggataacca ttagattggc acttaaggag ctagagctgc gtgggcttat
    12961 ttacaaacag cagggcaagg ggacctatgt atcaggcata aaggagcctg ctacagacct
    13021 gtcctcagcc tatagcttta ccgaagagat gaaaaagcaa ggtcgtaagc ctcaaacagt
    13081 cattctttca tttgaaaaaa tcaagaccac agcttacttg tctggtatgt tagatttaga
    13141 tgttgatact gatgtttttg agctagagcg tctaaggatt gcagatggaa agccattaat
    13201 gtttgagcgc acttatatac ctgaaagggg atttgaggcg ataacgattg atttattgga
    13261 aaaaaagccc ttatatgatg tgtttgctga ggattttcag gaagctatcc gattggctga
    13321 tgaggagttt tacgctagta tcgctctaga ttatgaagca aagctattag ggatcaaaaa
    13381 gggggatcct gtgctgcata ttatgcgtaa gacctataat gagaaaaata ggctaatcga
    13441 atttaccttt agtattgcta gagcagacca gtttaggtac cgtatccagc accaccctaa
    13501 caagaagata taggaggtaa ggaaatgttt acaaaaacac aagcagaact agagctactt
    13561 ggcgcagcta tcaccactag agaaatcaag cagcagccag agctatggtc agaggtcttt
    13621 gagtcttttc tgaagcaaaa aaaagacctc ttagcctttt ttgacaggat tattgaaagc
    13681 gctaacagaa acaaggtaaa aattattttt acaggagctg gaacttctga atacattggc
    13741 aataccattt gtcattattt ggagatgact ggtgacaggg aaaattattt atattacagc
    13801 attgcttcca cagaccttgt tgcagctcca agccagtatc tctttgaaga ggatacagtc
    13861 gtgcttgttt cctttgcaag aagtggcaat agtcctgaaa gtgtcgctgc tgttagtctt
    13921 gttaatcagc tggtgtcaaa tccttatcat ttggtgataa cctgtgccaa agagggggcc
    13981 ttagctcaaa atgctaagaa ggacaaaagg agctatttat tcttgctgcc tgaggcctca
    14041 aatgacgctg gctttgctat gacgggaagc tttagctgca tgatgctagc ggccttgttg
    14101 atttttgatc aagcgcattc ccttgaggag aaaaaatgct atttagatca gattgtaggt
    14161 atggtggcag ctattattca gcaggaggct gatttacaaa agctggttag cttagagttt
    14221 caacgcttgg tttacctggg atcaggagcc ttagcggggc ttacgcaaga ggctcaattg
    14281 aagattttag aattaacagc tggcaaaatt gcaacagtct atgactcctc aatgggcttt
    14341 aggcatggtc caaagtcatt tattgatgat cagacattgg ttattggttt tgttagcaat
    14401 gatccttata cgagaaggta tgaccttgat gttttagaag agataagaga ggatgctatt
    14461 gctgttgata cggttgcatt acagcagcaa ggaggtgagg gctttagtgg gcattgcttt
    14521 ggcttagact cgtcaatgct attgccagat gcttatttgg cctttccgct tgtttttatc
    14581 gcccaaacgc ttgctttgct gtcgtctatt aaggttaata atttaccaga tactccttcg
    14641 gccacaggaa cggttaacag ggttgtccaa ggtgttaaga tttatcacta ttttaagtag
    14701 gagaacaaga tgtaccattt atcaaaagct aagtatcgtc ttcttgaaaa ggtcagtcgt
    14761 aagggcatca tttcggcctt ggcctttgat caacgcgggg ttttaaagcg catgatggca
    14821 gcccaccaag acacagagcc aactccttgg caaatcgaag ccctaaaggc tctggtatca
    14881 gaggagctaa ccccctatgc ctcctctatc ctgctagacc ctgaatatgg cctgccagcc
    14941 accaaggtgc gtgatgagaa gtctggctta ttattagcct atgaacaaac cggctatgac
    15001 acaaccacca ctagccgcct gccagattgt ctggtggact ggtcagtcaa gcgcctcaag
    15061 gaggccggag ctgacgcagt gaagttcttg ctgtactatg atgttgatgg tgatgagcgt
    15121 attaaccaac aaaagcaggc ctatatcgag cgtatcggct cagaatgtca ggcagaggag
    15181 ataccatttt tccttgagct attgacctat gatgaggcga taacagacaa tcagagtgta
    15241 gcttttgcca agctaaaggc acacaaggtt aatgaggcca tgaaggtctt ttcaactgag
    15301 cgctttgggg ttgatgtcct aaaggtagag gttcctgtca atatggccta tgttgagggc
    15361 tttgcagagg gtgaggttgt ttacagcaaa gaggaggcta tgcaggcctt tcgtgaccaa
    15421 gaggcagcta gtcacttgcc ctatatttat ttgagtgcgg gtgtatcagc tagtctgttt
    15481 caagagacct tggtttttgc ggcagaggca ggagctaggt tcaatggtgt gctgtgtggt
    15541 agggccactt ggtcaggagc agtagcggtg tacatgtcag agggcgagga ggcagcgcgt
    15601 caatggcttc gcacagaggg ttttgaaaat attgatcgtc tcaatcaggt gcttgagaaa
    15661 acagccagcc cttggacaac aaagcttact cttgatgaag cctagtaaag gcatgataaa
    15721 agcaatacta ggacattgct tctgtattat tggtaatcac tggaggacaa ggcgtacttg
    15781 aaaaattgcc aatgcttgta ggactcggtg tactctagaa tacggccatt atctgtcgac
    15841 cgagtgagct tggtttgaag gacacaagga gtgttgtcta tcatgtttaa aaatgtagcg
    15901 acatctttag gcatgtgatc cgtcagctgt gtttgctggg tgaagctttg tgatcgcatt
    15961 tgaatgtgaa aatccaaaaa gaagcgctta taaagcgact ggtaatcagc taaatcacgc
    16021 tcagggcaca gcaggtaatc atgaggaata taagatagct ggtataaata gggctgctga
    16081 ttaatcgttc gtgtacggga gatggtgtag taaaattccg ttttatgaag tttcaagaga
    16141 tttagatagt agggatcatt tcccttaact acactaagga cagtcacctc ctctttttga
    16201 tccttaaagg tacctagata ggaaaattgg actagctgtt cttttctggt acgggtaatg
    16261 aaggttccaa gtccctgcct tcttctgata aagccttctt tttctagttc tttaagggct
    16321 cgaatgatgg ttatggagct aacatgaaag cgtttaatca gctcggcttc ggtataaaat
    16381 ttgtccccgg tatggtagtg gccattcaga atttggtttt gcaattcttc tttgattagt
    16441 cggtactttg ggtatttgat ggtcatagtt actcactcaa taattgttta gtacgattat
    16501 agcaaaaata gtaagctgat gtcatatctt accagttatt gctcagatag cttgtcaatc
    16561 agtcattgat caaaggctga tggttaatga ataaaaggag ataatatgaa gcaattttgc
    16621 ataaaggagc agttttacct tgatggcaag ccgtttaaga tattatcagg tgccattcat
    16681 tactttagaa tagctcctga tagctggtct agggtgcttt atcagctgaa ggccttaggc
    16741 tttaatacag tagaaaccta tattccttgg aatatgcatg agccaaggaa gggacagttt
    16801 acctttgagg ggattgcaga tgttgaggca tttttggatt tggcacagga atgtggccta
    16861 tatgctattg tcagaccctc tccttatatc tgtgctgaat gggagtttgg tggtttaccg
    16921 gcttggctat taactgaaaa ttgtaggctc agatcaagcg atgaggtctt tcttaagcat
    16981 gtatcagatt attatgatgt gttactacca aagctggtga agcgtcagtt agataatggc
    17041 ggcaatattc tgatgtttca gcttgaaaat gagtatggtt cttatggtga agaaaaggct
    17101 tatttaagaa aattaaaaga gcttatgctt gctaaaggca ttagtgcccc tctctttacc
    17161 tcagatgggc cttggccagc cacgctagca tcagggagtc tgattgacga tgatgttttt
    17221 gtgacaggca actttgggtc aaacgcttca aagcaatttg ccagtatgca ggattttttc
    17281 caagcacatc aaaagcaatg gcctctgatg tgtatggaat tctggttggg ctggtttaat
    17341 cgctggaatg agccaatcat tcgaagggac tccaaggaag ctgttgatgc aatcatggaa
    17401 gctatagagc taggcagcat taacctttat atgttttgtg gtggcactaa ttttggcttt
    17461 atgaatggct cgtcagctcg tctgcaaaag gatttaccac agataacctc ctatgattac
    17521 gacgcattac tagatgaggc agggaacccg acaaagaaat ataccctgct gcaa
//
LOCUS       DARYLD010000046        16872 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYLD010000046 DARYLD010000000
VERSION     DARYLD010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16872
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(183..935)
                     /gene="pstB"
                     /locus_tag="TU651_001413"
     CDS             complement(183..935)
                     /gene="pstB"
                     /locus_tag="TU651_001413"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL0897400.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            complement(937..1752)
                     /gene="pstA"
                     /locus_tag="TU651_001414"
     CDS             complement(937..1752)
                     /gene="pstA"
                     /locus_tag="TU651_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL0897401.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            complement(1745..2608)
                     /gene="pstC"
                     /locus_tag="TU651_001415"
     CDS             complement(1745..2608)
                     /gene="pstC"
                     /locus_tag="TU651_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL0897402.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            complement(2678..3550)
                     /locus_tag="TU651_001416"
     CDS             complement(2678..3550)
                     /locus_tag="TU651_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL0897403.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            complement(3709..5034)
                     /locus_tag="TU651_001417"
     CDS             complement(3709..5034)
                     /locus_tag="TU651_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL0897404.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            complement(5018..5740)
                     /locus_tag="TU651_001418"
     CDS             complement(5018..5740)
                     /locus_tag="TU651_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897405.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            5912..6067
                     /locus_tag="TU651_001419"
     CDS             5912..6067
                     /locus_tag="TU651_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897406.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            6108..7010
                     /locus_tag="TU651_001420"
     CDS             6108..7010
                     /locus_tag="TU651_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL0897407.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            7010..7825
                     /locus_tag="TU651_001421"
     CDS             7010..7825
                     /locus_tag="TU651_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL0897408.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(8010..9431)
                     /locus_tag="TU651_001422"
     CDS             complement(8010..9431)
                     /locus_tag="TU651_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL0897409.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(9458..11320)
                     /locus_tag="TU651_001423"
     CDS             complement(9458..11320)
                     /locus_tag="TU651_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL0897410.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            complement(11325..12164)
                     /locus_tag="TU651_001424"
     CDS             complement(11325..12164)
                     /locus_tag="TU651_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0897411.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            complement(12453..13910)
                     /gene="ftsY"
                     /locus_tag="TU651_001425"
     CDS             complement(12453..13910)
                     /gene="ftsY"
                     /locus_tag="TU651_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL0897412.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            complement(13910..14737)
                     /locus_tag="TU651_001426"
     CDS             complement(13910..14737)
                     /locus_tag="TU651_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0897413.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            complement(14738..15535)
                     /locus_tag="TU651_001427"
     CDS             complement(14738..15535)
                     /locus_tag="TU651_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL0897414.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            complement(16053..16562)
                     /locus_tag="TU651_001428"
     CDS             complement(16053..16562)
                     /locus_tag="TU651_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897415.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            complement(16559..>16872)
                     /locus_tag="TU651_001429"
     CDS             complement(16559..>16872)
                     /locus_tag="TU651_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0897416.1"
                     /translation="KKIIADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRK
                     IILADEPTGALDSEIGKEIINLLLSETAENKYVIIATHDPAVYNKVDVIIDLKDIGSE
                     I"
BASE COUNT         4841 a         3980 c         3177 g         4874 t
ORIGIN      
        1 agtaaccttt gtctgaaaat agctagatcg tgcttatcaa agaaagcaaa aaagcttcac
       61 tctacaggaa gtaagagaga agcttccacg ctaataggat actgatctga catcatcaaa
      121 acaccaattg aggagagatt tagccctcat tccaattgct ctttcatcgc ctagtccttt
      181 tcttatccga agcgtccgga aatataatcc tctgtacgct tgtcctttgg ctttgtaaat
      241 agttcagctg tatcgccaaa ttcacaaata tctcctgtga ggaaaaaggc tgttttatct
      301 gacatgcgtg aagcctgctg catgttgtgg gtaacgatga taatcgtgta atcctgcttt
      361 aattgctgaa ccaagtcctc aatttttaag gtagaaatgg gatcaagagc agaggtaggc
      421 tcgtccatga gcaacacatc aggtgctaca gcaagcgctc ttgcaatgca aagccgctgc
      481 tgctgtccac ctgataggga catggcactc ttttttaagc tgtctttgac ctcgtcccaa
      541 atggctgctc ctctcaagga ctgctctacc agctgatcta gagttttctt gtccttaagg
      601 ccatgtgtcc taggaccata agccacatta tcataaatag acatggcaaa tgggttgggc
      661 tgctgaaaga ccataccaac acgcttacgc agactgttga ggtttattgc tttagcatag
      721 atgtcttgat tgtctaagag aacctctcct tcgatacgac aggaaggaat caagtcattc
      781 atgcgattta gggtttttaa aaaggttgat ttgccacagc cagagggacc tatcagggct
      841 gtgatctgat tttctggtat gtcaatggag atatccttta aggcctgaaa tgctccataa
      901 aagacattaa gctgcttggt tgaaaaagct cccattttag acgactcctt tcactaatcg
      961 gcgtgataat aagcttgata gggcattgat cagcaagaca gttatgagta agataacacc
     1021 cgttgcataa gcttccttga catgtagccc ttcgctagac agcatgtaca tgtgaagagc
     1081 tagtgagcgt cctgatgaca tgaggctggt tggcgtattg gtagaggtgc ctagggtata
     1141 catcagggct gctgtctcac ccacaacacg tccaatcgct aggattaccc cggctagaat
     1201 accaggcatt gcagccggca gcactatttt aaaaatcgtc cttagcttac ctgctcctaa
     1261 gccaaggcta gcctgacgca agtgatcact aacagagagg agcgcttctt ctgttgatcg
     1321 aatgataact ggcaacacca tgattacaga cgtcagaata cctgataaaa gagaatattg
     1381 caggccgaaa aaaaccacaa agaacagcat gccaaaaaga ccaaaaacaa tcgaaggaat
     1441 ccctgatagc gtatcagctg caagacgtat tgcccttacc catagtgagt cctgcttagc
     1501 gtattccaca agatagaagc cagcaaagac accaatgggc aaggctagca ctaaggtgcc
     1561 taaaactaga ctaacagttg agataatcga cggcattaga gaaacattgt cagaggtata
     1621 ggtccatgaa aataaggata acgacagact aggcaagcct tttatcagca taaaggcaat
     1681 aatcaaaaat aaggagccaa aggtcaatag cgacaaaaga tagaccaggg cttttagtaa
     1741 atagttagtc atgagctgat tttcctttca cataagcaaa gcaagcatta atgatgagaa
     1801 taaagccaaa gaggacagcc gatgttgcaa tcaaggcctc tctatgctga ccagaagcat
     1861 atgccatctc taggacaata tttgtcgtca tggttcttgt gccctcaaat aatcctgatg
     1921 gcagcacagg ctggtttcct gctaccaaaa taactgccat cgtctcacca atggcacgac
     1981 caaatcctaa aataagagcg gaaaaaaggc cggatttggc tgctggcagg atcactcgaa
     2041 aaatactcct ttcatgactg gctcccagtg caagactagc tgaataataa gcctttggaa
     2101 cagctctgat agcagactct gaaagactga taagcgttgg caaaatcatg attcctaaga
     2161 gcaaggaggc agtcagcaca ctcatgccat taccagcaaa gctcctaatc caaggcacta
     2221 gcacttgaag accaaaaaag ccataaacga tagacggaat ggctgccatc agattaacag
     2281 ctgactttaa aaagccatag catgctttag gacaatagta aaccataaaa actgaggtca
     2341 atatacctgt tggcacacca atcaccattg caccaagtgt gatgacaaaa gaccctgcaa
     2401 tcatcggcaa aataccatag cttgccggct gatttgacgg tgaccaatca tttcctagca
     2461 aaaaggctct cataccatac ttagcaataa agggaaggcc attactaaaa ataaagatac
     2521 agattaaaca aatagcaata attgccatcg ctgcactgag aaagaagata actttaaaaa
     2581 aatcctcttt aaaggcttgt ttattcactg atgatccttt ctaagaaagg aaagcaagaa
     2641 caaaacacct cttctttgcc ttccttctaa tcgttcttta tttgactttg tcccagcttg
     2701 ttagcttgcc gctaaagaca tcagccagca catctatgcc aatattactt accttattgt
     2761 ccttgtgaac aatcactacg ataccatcaa gggcaatcgc atcatcaatt aagcccttgc
     2821 tctcctcagt tgttaggtca cgagaaacca taccgatgtc tgctgttttt tccttgacgg
     2881 cggtgatacc tgctgatgag ccatttgagg taatatcaat gctaatggct ggattttctt
     2941 tcttgtatgc ttctgctaat ttttccatca agggtgaaac tgaggttgag cctacaattg
     3001 acagcttgcc tgataagccc ttactgctat aggctggcgc gtctgttttt gcttcgatca
     3061 atcgattgtc tctaacaatc tcctgcccct gctttgagtc aataaaggtg ataaaatcct
     3121 taccaactcc tgataggtct gaggaccata caatattaaa gggacgctgc agagggtatt
     3181 tcccctctaa aatagtctca cgactagcct ttacgccatt tacctttagg gctgcaacgt
     3241 cgctatttaa ggaccctagc gagatgtagc caatggcacg actatttccc ttaacagagg
     3301 agatgacccc ttctgtgcta ttttggataa tagctgtttt tgctgtttgg tcaatctctt
     3361 tgtcaccgtc cttttttaga atgcctgtca tttcggtaaa ggctccacga gtacctgagc
     3421 cattttctcg agaaacaagg tcaatcctgt ctgctgcttt tccagcatca gcactgttat
     3481 tgccacaggc tgcaagacct aagcctgata agccaatagc tgccatgatc agcatttttt
     3541 tgattgtcat aagaatcacc cttatctttt atgatattgt gttgtaggct tgctacacct
     3601 atagcttatc aggtctttgt aaaggtttat ccctgattaa tgtaaagatt ttgtaaaacc
     3661 taaaacagcc actaccaagg ctggccttaa gtagctggta gtgactgttt acttgttgat
     3721 agcttctggt aagaataagg taaattggct gccctctcct agctgacttg tgactgttat
     3781 ctgaccgcca agaagctgac tcagctcctt tacaatggct aggcctaggc ctgttccacc
     3841 actttgcctg ctacgtccct tgttaacacg ataaaagcgc tcaaaaatac gatctagctc
     3901 aatttggcta atgccaatcc cagtatctgc aactgtaatg gcaacaccac cagcaaccct
     3961 ttgactggat agctgaattc tgcccccatt gtctgtatac tgtatcgcat ttgataagag
     4021 atttaacatg atctgcgata agaggtattg atcagatgtc acaacaatcg aatcctccaa
     4081 tgcatagctt agctcaagct gcttttgctc tagctgtggt ctcatgctct gacctgtata
     4141 cagcaggaag ttcctgagct gaaactctgt caggtcaagt ggtgtcttgt tagccttgga
     4201 taaggtcagc aggtgctcaa caatacgttc tagacgcaag ctttcattgt agataatgtc
     4261 taaaaagtct tcttttaggc ttgtttcatc gtcaggcatt tccttaatcg tttcagcaaa
     4321 gcccttgatc gatgtaaccg gtgttcttaa ttcgtgagaa gcattagcaa taaactccaa
     4381 atttagcctc tcataatgac gaatggccgt cagatcatat aagagcacta aaatctcctt
     4441 gacaacatgc gactggttaa agataggcac aagggtaacc tccaagatca aatcaccatc
     4501 atgtaggcct gttaattcct tctttaatgt ctgcttttgg tcaaagactt gattaactaa
     4561 ggctatcaga tccattcgtt taagatcctc caagaccaca aaaggtggct tagcctctgg
     4621 aaaataagcc ggtaaggatt tgctggtcag caacagctcc ctttgattgg agactaaaag
     4681 catgcccatc gtgagatgag aggttacagc ctccacattt tttgataagg cttttagcct
     4741 tgcttccttt tgtaataggt cactttttag ctctgtcagc tgcttagcat aagcacttaa
     4801 atcagcctgc cccactagga gaaaatggtc actagctgtc aaaagatggt ggtgcaaggc
     4861 tctgaattca cgctcccatc taaatagcat gctcaagaca taaaagctag ctacgagacc
     4921 agtacacagc actactagag tcagcacctg atgcggccct tgccaaatca gaccaagagc
     4981 agccagcaag caaagcccta gcagcatgct caaacgccta agatgtccta tcattcttta
     5041 gctccttaaa tttgtagcca tagccgcgaa tggtttgaat atactgaggc gccttaggat
     5101 tgtcctcgat tttttctctg agcttgccaa tatgaacgtc taccagacgt gtttcttggc
     5161 caaagtcata accccagata cgctctaata gccgctcacg cgtcagggtc atattagggt
     5221 gcttcatgag atagagcagt agctcatatt cctttggggt taacggcaat agctccttgt
     5281 ccttatagac ctcatgtcgc tctgggtaca gacgcaattg actcatcgta taaaaaggct
     5341 cacgacgctc ttcaccatca ccagaaatct ctgcttcagt acgccttaaa atagccttga
     5401 cacgcgctaa taattctcta ggactaaagg gcttggtcac ataatcatct gcccccagct
     5461 ccaaagccaa aaccttgtca aattcatcac ttttagcaga aaccatcata attggggttt
     5521 tgcttccctt agcacgaagc cttttgcaga cctcgatacc gtctaattgc ggcagcataa
     5581 tatctaacac aataaaatca taaggttctc tttcagctaa tgccaaggca gtacggccat
     5641 ctgttaccat ctctgtcaca aagccctcct tggccaagtg ataatccagt agccttaaga
     5701 taggctcctc atcatctact aataatactc gttttgtcat ttcatagctc ccatcagcca
     5761 cattatatca tatttgtcag tcaatctaat gacacactgc ttgacggcct gaagcctaaa
     5821 atcaatcaga agataaaaag atgttttagc tttggcttta ccgtcaaatg attgtataat
     5881 agagctatat tgattgaaag aaggtatacc tatggcaatt actcataaga aaaatgacca
     5941 gctcgaaaag atgatggcag gctttgcgtc tatcccagat tttgataagc ctttagagct
     6001 taaccaagat ggaaagctag tcactgaaaa accaaagcca caagtcaaga cagctaagca
     6061 ggactagccc ttattggcgt cgttaacata tagaaaggat acggtgaatg tcgctttttt
     6121 caaatctgcc acccagcgtg cttcaatggt ttgcgatttt tctatccatt atcattgaag
     6181 ccctgccttt tgtattttta gggactattt tatctggctg tattgaggtt ttcgtcacgc
     6241 ctgatttagt tcaaagatac ctccctcaaa ataagtggct aagaatttta tttggtacct
     6301 ttattggctt tgtttttcct tcctgtgaat gtggtatcat tcctattatt aatcgttttt
     6361 tagaaaagaa ggtgcctagc tacactgctg ttcccttttt agcaaccgct ccaattatta
     6421 atccgattgt tttatttgct acctactctg cctttgggaa ttcgctgcgc tttctcatgc
     6481 taaggctttt aggcgccatt ttagtggctg tcagccttgg catcatgcta gccttcattg
     6541 ttgatgagaa cattctcaag gaatcaaccc agccggtgca ttgtcatact tacagtcacg
     6601 aaagcctgcc aaaacggctt tacttggcac tggctcacgc tattgacgaa ttttttgata
     6661 caggaaggta tctagtcttt gggaccctga ttgcttcagc catgcagatt tatctgccaa
     6721 caaaggtgct gacagcgatc ggacatagcc ctttgacagc catcttagtc atgatgctct
     6781 tagcctttat cttatctctt tgcagtgagg ctgacgcctt tattggagct tcgttattgt
     6841 caacctttgg agttgctcct gttttagcct ttctcttaat cggccctatg gttgacatca
     6901 aaaacctcat gatgatgctc aattccttta agggagcctt tattgttcaa tttatcagtg
     6961 tatcagctgt gatgattacc atatattgct tacttgtggg ggtgctgtga tgattcgctt
     7021 tttaatttta gcaggctatt ttgagttgac catgtatcta gagctatctg gcaagctaaa
     7081 tcaatatatc aatattcgtt acgcttactt agcctatatt tctatggttc tatcctttat
     7141 ccttgcattg gtgcagctat acacttggac taaaaacatc aagctacaca gtcatttaaa
     7201 aggtaaggtc gctcagctga ccagtcccct tatcctggtc tttcctgttt tggttggctt
     7261 gttagtacct acagtcagct tggattcgac gaccgttgcc gccaagggct atacctttcc
     7321 attagccgca ggcgcttcaa aaacaggggt cagtgatgat ggtactacta ttcaatacct
     7381 aaagccagac accagcctgt actttaccaa atccgcctat caaaaggaaa tgctcaatga
     7441 actgaaaaaa taccaaggca aatcagccat caccattacc actgacaatt atatggaggt
     7501 aatggaatta atctaccttt acccagacga attcgttgat cgtacgattc agtacactgg
     7561 ctttgtctat aatgagccag gacatgacag ctatcaattc ctctttagat ttgggattat
     7621 ccattgtatc gctgattccg gtgtgtatgg gcttctgacc actggtaatc aagaaagcta
     7681 tgccaataac acttggctga ccgtcaaggg ccagctgcac atggaatatg acaagaccct
     7741 agagcagcag cttcctgtcc ttcaaatcga ggaagcacac caagccccag agcctgataa
     7801 cccttatgtc tatagggtat tttaacaagc attaagcctc cacacctatg acacaggtct
     7861 atggaggctt tttgttaggg gacagtacaa agacgtaatt gagttcgttc catttaaatg
     7921 aaatggctaa aagccgtata gcatcagcct tttaaaagac gtgtgctata cggctttgct
     7981 attgttggta aagcctttga ggctactttc tagctctcct cagacaggct acgcccattg
     8041 gtctcaatga ccctttgata ccaagcaaag gattttttct tgtagcgtgt caaatgacca
     8101 ctgccatcat catgtcggtc gacataaata aagccataac gcttacttag ctgagcagtc
     8161 gacatagaaa cacaatcaat acagccccag gaggtatagc ccataatgtc aacaccgtcc
     8221 tcaatagcct tagcaacctg caataaatgc tgcctcatgt aatcaatccg ataatcgtcc
     8281 tgaactgtcc agtgaccatc ctttgtctgt actagcttat ctttggcgcc aagcccattt
     8341 tctacaataa agagaggaat ttggtaccta tcatagtaat cattcaaggt tatgcgaagg
     8401 ccaattggat caatttgcca gccccattcc gaagagggca gatgaggatt aaccaagcca
     8461 cctaaaatat tgccctcccc tcgttgataa tgatccgggt gatgagactg agtcacactc
     8521 atgtaatagc taaaggataa aaagtcaacc gtatgctgcg ccaaaagctc actgtcgccc
     8581 ggttcaaatt gaatgtcaat gtgctgctcc ttaaaaaagg atttggcata ggaagggtat
     8641 tttcctctga cctgaatatc tgagaacagg agattacgtt gctcaaactg cttcgcagct
     8701 aaaatatccc tcggatcaga ggtcattgga taggctggca tagccaaaat catacagcct
     8761 attttaaaag cagggttaat caatctagca agccttgtca cactagcaga cgctactaat
     8821 tcatggtgaa tcgcttgata aagctcctgc ggagtcagct tttcctttgg tgtcatgata
     8881 gcaccactgg taaaaggcat atgcaggatt gaattaacct cattgaaggt taaccaatac
     8941 ttaaccttgt tcttgtagcg ctgcatgaca gttgtcgcaa aacgttcaaa gaagccaacc
     9001 atacgacggt cagtccagcc attatagacc ttagctagat gcagtggggt ttcgtagtga
     9061 gatagggtca ctaaaggctc tatgccatgt gctatcagct catcaaacaa atcgtcataa
     9121 aattgtagcc ctgcttcgtt aggctctgtc tcatcgccct gaggaaaaat acgagaccaa
     9181 gcaattgatg tccggaaaac cttaaagccc atttctgcaa agagcgccac gtcctccttg
     9241 tagcggtgat aaaaatcgat ggcctctagc ttcaaattag ctgctgttgg ctcagctgta
     9301 tagtctccta agcccccttc tggtaaaaca tcctgaaccg acaagccttt gccatctgtt
     9361 aaataagctc cctcaacctg attggcagca actgcccctc cccacaagaa atcctttgga
     9421 aaacaaacca tattatctcc tccttcaatt catctcttta gagaataacg agagcaacat
     9481 catgctgagt gatatgctcc ttgttgtcat taacaatgat ttcgagctgc tcagagctat
     9541 tggtcaccac aaatggagtc actaaagaat agcccttaga gccaatcaat tcaagatcta
     9601 tacgtagcag cggctgcccc tgcttaacag tatcaccagc cttaaccagc tgctcaaagc
     9661 cctgtccttt tagctcaacc gtatcaatac caacatgaat taagacgtca actcccttgg
     9721 cgttctttaa agcaatagca tgctttgttg gaaaaagggt gataacctcg ccatcaaatg
     9781 gggcatagac atattcctca ttaggtaaaa tagccagccc ctctcctaaa agcttagacg
     9841 aaaaggtttc atctggcacc tctgataatg gaagcactgt gccaaccatc ggagcataaa
     9901 tagattgctt tgctgataag ccacttttta ctggcgtgct atccgagtca gctgacccct
     9961 cctggtcaac ctcctcatca atgccaaaaa accaggttaa tgtaaaggtt agagcaattg
    10021 ttaagcccgc tgcaattaag gcattggtaa aattagcaga gctagtcggg ctaatgtatt
    10081 gtggcaatcc aattagtgat ggcaccacaa aagtataaga ggctatatta acaaagccaa
    10141 tataggcgcc cacaaggcca ccagaaatca ttgcagcata gagcggcttt ttaaacttta
    10201 gagtaatgcc ataaagagca ggctctgtaa ttcctgccaa taaagctgat aagcctgctg
    10261 ctaaggcaac ctgacgggtt tgcttttgct ttgattgaca tgctacagcc accgctgctg
    10321 atccctgagc taggttagag gctagcattg ctgggaggat taaaacatct ggagttgcta
    10381 cagaggccgc cagaaaaata ggagcaaagg cccaatgcat acccgtcata acaacaagcg
    10441 gcataattgc acctaaaata gcaagagcca gccaaggagc aatatggtaa atcgctagca
    10501 ggctattaga caagccctgt cctataataa cacccagagg tccaataaca actaaggcta
    10561 gaaagcctga aataaaaata atcaaggtcg gctgcaggaa gctcttcatc acactcggta
    10621 caaaacggtt aacctctcgc tcaatgtatt gcatcaggta aaccataatt aaaatcggaa
    10681 taactgacgc accatagcta gcaggtgtca ccggcgctcc aaacaaagcc ataggtttac
    10741 ctgtagctac catcgtaaca aaagctgggt gtagtaaaat ccctgcaaca gttgctgcta
    10801 atacaggtgt gaccttaaag cgtgccgcag ctgaatatgc aatcatgatt ggcataaaat
    10861 aataagcagc atctccaaaa aaattaataa aagcaactgt ttgagagtcc gtacctgcta
    10921 gaccaagcat aggcaccaag atcccaacca cctttaacat accgcctccc agtaaggcag
    10981 gtatcagtgg agtaatcaca ctagctatcg tttcaatcaa cccttcaatc atagactgct
    11041 tttgaccagc gctagagctc atatcagttt catgaaactg tcctagggtc ataaatgcct
    11101 tataataatt gttaacatcg tttcctaaaa taatttgata ctgaccgttt tggcgcatga
    11161 ctccaatcac attaggaata agtttgattt tttgatctac cacttgttta tcatctttca
    11221 aaaccaagcg taaccgcgtg atgcagtggg ttacctcttg aatattctgc tcaccaccaa
    11281 ctgcttcaaa aatggccttg gctgtttctt gataagtcat ttcattactc cttcacattt
    11341 ttgactaaac gtttgatatg aaccgttaaa tacaaaagct cactagagct aagctgataa
    11401 tggtatgctt ttttcatgtg atggctaatt tgcctaacac agtgatattc ctctgggtat
    11461 ttatccttaa ccatcagcag caaatcagtc tcgtcatcat cataagccat gcctgataac
    11521 acgcgctgag caaatagctt cacatgagtg ataaagcgat aataatcaat agagacttca
    11581 tcaagctctg tcttaaaatc agccttgacc ttctgttcaa tgtaagacac aatttctgtc
    11641 attcgatgag gctccttgaa aggattatca aggctcgcgt tgacaaagtg catcgcaata
    11701 aacgaagctt catctacagc cagagcgact cctagctcac tggcaatgac ctctaaggcc
    11761 ttaacgccaa tcgcatattc atcaggataa taccgtctaa tctcccagcg caagggatca
    11821 ctaatgatca tcccctgctt atgtctttca atagctgaat gaatatggtc tgtcaaattg
    11881 atatagagta tttcatctaa atttttaccc agcttaattt tccctagatt aataagcctc
    11941 tctgagcaag caaccacctc ttgcggaaca gcaataaata attcagtaaa acggttcata
    12001 ttgtcactat tttttaaaac aaatgacgct tcgatagctt cactatcgat atggtcacca
    12061 attcttttct taaaagcaat cccctttccc atcaaaagaa tatctagccc ctgatggttg
    12121 gtcgaaatcg ctgcattatg gtttaaaacg cgtttaataa tcataaaagt cctagtccct
    12181 cattgcttca caataaaaaa tgacctatcc acagcatgct aaaaggccac actggaatag
    12241 gtccctgctc acaaaactgt gataacatcc tttaatattc tgattcattt gtcattagca
    12301 cgcttaccct aagtaatcac atctaataac gttttcattt tatcatctcc taaaggtcct
    12361 gtcaagcgtt ttcaaaaggc tgtttgacat ttgcctctaa acgaaccccc tcattctctt
    12421 tggccaacag ccgataatct gaggctttcc tcttaaagta tgccttctaa tagtcccttc
    12481 ataaagtcct cagagtgaaa ttcaccgata tcatcaatag cctcaccaaa gccaatcagc
    12541 ttcactggga tatccaattc ctgacgaata gctaggacaa ttcccccctt agctgtaccg
    12601 tcaatcttag ttaaaatcaa gcctgtgagc ggtgtgattt ttgaaaactc cttagcctga
    12661 ctcagagcat tttgccccgt tgaggcatcg agcgctagca gggtttcgtg tggggcatca
    12721 ggtatgacac gcttaatgat tcgtcctatt ttttcaagct ctgccattag gttgtcctta
    12781 ttttgcaggc ggcctgcggt atcaatcagg agaatatctg ccctttcagc aacagccctc
    12841 tcaacgccat caaagaccac agaggccgga tctgcttttt cagggcctgt aatgaccggc
    12901 acatcaaccc gtcgtcccca ttcaaccagc tgggcaaccg cgcctgctcg gaaggtatca
    12961 gctgcaacaa gcataacctt ttttccctct tgcttatacc gataagctag ctttccaatt
    13021 gatgttgtct taccaacgcc attcacccca acaaagagca taacggtcaa gccaggctga
    13081 taatgaatcg cttcattgta gcggccatcc ccctcataaa tagccactag cttatcaatg
    13141 ataagacgct ttagagcctc tggcttttta gcattttcaa gcttagcctc atagcgcaat
    13201 tcttcagtca aggttgtggc aacatgaaca ccaacatctg agagaatcaa aagctcctct
    13261 aagtcctcaa agaagtcctc gtcaacacgt ctaaagttag caaagaagct gttcaagcgt
    13321 gctgaaaagc ctgtacgggt tttctttaag ctgcgcttgt atttttcctg atcagattca
    13381 gctgataggg tctcttgctt ttggccttcc tcagctggct gatcagctga accagcaggt
    13441 gcttgagctg ctacttgata ctcagcattt gtctctgcct gatcttctgt tgatgcgtct
    13501 gcgctctcgt tactatgctc tgacttagcc ctatcatgct tagcctcctc catagcctcg
    13561 tgctggctta ggctctcacc tgcctgatcc aaggtcttgt catcagtagc tgctaactct
    13621 agctccggct ctctttctaa aagaaaagct cctctagctg ctggatcaag cccttcagct
    13681 tgctctgaag cagcctcgtc tgagagctca gcctgtttgc tagtgtcatc ggtcctagag
    13741 accacatcag ctgccactgc atgagcattt gtatctgata aggcctcctt ttcagactca
    13801 atcgtatcct ttgacgttat gtcctccgac aatacctctg tagtggcagc ctcttgctca
    13861 gcaaccttag tcttatcctt ttttccaaat aagcgttcaa ataatcccat tagccttcct
    13921 catttaaaat atatttccaa atagcctcag ccacacctga ttggtcattg gttagggtag
    13981 tcactgcatc tgccacttcc ttagcctgat caaccgcatt ggccatagcc acaccaagac
    14041 ctgcccattg tagcatgcta aagtcattgg cctcatctcc catcgccatg acatgcttgg
    14101 cctccaagcc caagtgctga caaagcaggt ccaaaccaaa tgccttatga atccccttag
    14161 gcataatctc aaagatgatg tctcgtgatt taaaggcctc aaaatcctca aagatagtct
    14221 ttggaagcct tgcaagctgc tgatccaaga cctttggatc cgtcaccgta acaattttat
    14281 tgtatgtgat gtcctttggc agctcagcaa atgatttaag gctaacaaag ttcagcaagg
    14341 gacttgccaa gtgatactga gagcgtctgc catcattgcc tgatagacta taaacagtac
    14401 catcactgat aacatcagta ggtaagccaa ccgctgccaa ctgctgatga atgtcataaa
    14461 cctcagcaag gcttagagcg cttttatcta aaatatgacc agtatttcgt tgaaccagac
    14521 cgccattaaa ggtaatgcta tagttctctt cacctagcaa atccagctcc tcaagcaaat
    14581 ttccgatagc cttaagagga cgtccggttg tgataacaac cttaactcct ttttccttag
    14641 ctgctgctag agcttttttg ttctcatcac taacgatttt ttcggtatta tagagagtcc
    14701 catctaaatc tagagctaaa agctttatac gcgtcattta caccaatccc tccaaataag
    14761 ttaacactgc tgagtcatta caatgaccaa taacctgatc agaaatcgct ttgatttcag
    14821 gccttgcatt ttcagtagca atagcctgcc ctgcaaagga cagcatttga taatcattta
    14881 gattatcgcc aaaggcaatg gtcttttccg gtaaaatgcc taggtgctga cacagctgat
    14941 ccatgccaaa gcccttatga acctctttta ggataatatc aatcgaatca aagccagtcg
    15001 tcaccgcaga agcataggac agctcctgat ttagccagtc actgccagct aagactgttt
    15061 ctcctgtaaa ggtcgttgag gctttaaaaa cagtgtcatc aacaatatcc tgcagacaat
    15121 caataagctg aacattttca taataataat gcattttttg gatataatcc tccgtagctc
    15181 ctttgagcac ataggctgcc ttttgccctg aaaagaggat cccagactga ttgtaataag
    15241 gattggcaag aattttctct acaatgtcat gacactgctg cttggtcatg acatcagcaa
    15301 aaagaatgtc cctcttgtat tgcaccacag acccattctc agcgataatg gcaatgtcat
    15361 ctaaaaaagg ctcaaacaag tgatcaatgg ctaaaagcga acgcccacta gaaactgtaa
    15421 agagaatccc tttttctctt agcttaggca acagagctgc caagcgctcc ttgtcataag
    15481 ttccgtcctc tcttaaaaag gttccgtcca tatctgttgc tatcaattta accatacaat
    15541 ttaaccattt cctttttagg gagatactga ttcagctatt cagctctccc aaaaatctct
    15601 ttttccatta taccatatct aaacaaaaag ggcgtgcctg tcctaacacg tccttgtttt
    15661 aaggctttat aatttctgta gtgggtaact ccactgtgga gattattgag cccttattcc
    15721 aaggctttct ttatgttcta ttgtatcaat ttccttattc caatttctgt tgcaattaac
    15781 tttaacatac aatctaacca tttcactttc aagggagtgc aaaacccgag tggggtgtgc
    15841 aactcaaatc ccagtataac tcctttcgtt ataccacagg tagaccaaaa aagggcgtgc
    15901 catctgacat acccttgttt taacagtcaa tctgagctcc gtttttaaag gctaaacttc
    15961 tttatctcca tactctcaac gcttatttgc cataattctt aattgaagcc cgtcactaag
    16021 ttttcttgtt actaaagagt tgagtaatga atctatctag actgatgatt tttctcctta
    16081 aaagcttcat atagtttttt atataacgct ttcttttctt ttttctgagc attaaactct
    16141 tttttaccgt aatcaaaatt tgctaccaca aaccccttgt tattgttaga aaaatcaaaa
    16201 aattccattt cgattaattt gttattctta gaatcttcta tagtattctc taaatgattg
    16261 ttgaattgtt taacatcttc ttcactaact ccaaaaccca tagcagctcc gtctgcaatg
    16321 atgtttgaaa atatttcttc tgaagatgct gcttctttta cccttattag gtatatggct
    16381 tcttctgttt ctaattgtct tactttattc catttttggg tatcactaga agagatcgta
    16441 tagactgtta aatctaccgt aggtttattg ggattttctt tttttattac ttgttttccc
    16501 actaagaaaa ttgcgagtat tccaattaat aatatcaacg tcatataagc tttctttttc
    16561 atatctcact ccctatatct ttcaaatcaa tgataacatc aaccttatta tatacagctg
    16621 gatcatgtgt tgctataata acatatttat tttcggctgt ttcactcaat aataaattaa
    16681 tgatttcttt tccaatctca ctatccaaag ctcctgtagg ttcatccgct aaaataattt
    16741 tacgtggctt cattaacatt cttgcaatag ctacacgctg aacctgtcct ccagataatt
    16801 catatatttt ctgatttaaa tagtcattag aaagtcctac tttttcaagt acatcagcta
    16861 ttattttttt at
//
LOCUS       DARYLD010000047        16701 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYLD010000047 DARYLD010000000
VERSION     DARYLD010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16701
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..902)
                     /locus_tag="TU651_001430"
     CDS             complement(<1..902)
                     /locus_tag="TU651_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL0897417.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..2391)
                     /locus_tag="TU651_001431"
     CDS             complement(895..2391)
                     /locus_tag="TU651_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL0897418.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILELLNANLS
                     WISKNTSLKIEYKVIKDNYITSQTLEYNNMLGVSTKPEKYDVIIGNPPYLKVGKMANE
                     ALSMPDICYGSPNLYFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVV
                     LKHIHLFVSRDKVFDKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTVFEAS
                     YDMVVSGEHKYVFLITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEALRND
                     AEEKAVPLFYSQHIKDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKEEKRR
                     LQCGIYLAKKFPTYKAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYRILNG
                     STQVNATEINSMPIPPLTCIEDMGKELIKLKDMSEENCDEILGRFIYV"
     gene            complement(2375..2590)
                     /locus_tag="TU651_001432"
     CDS             complement(2375..2590)
                     /locus_tag="TU651_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0897419.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            complement(2740..3399)
                     /locus_tag="TU651_001433"
     CDS             complement(2740..3399)
                     /locus_tag="TU651_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0897420.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            complement(3443..5353)
                     /locus_tag="TU651_001434"
                     /pseudo
     CDS             complement(3443..5353)
                     /locus_tag="TU651_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(5461..7226)
                     /locus_tag="TU651_001435"
                     /pseudo
     CDS             complement(5461..7226)
                     /locus_tag="TU651_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            complement(7736..14566)
                     /locus_tag="TU651_001436"
                     /pseudo
     CDS             complement(7736..14566)
                     /locus_tag="TU651_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(14738..16165)
                     /locus_tag="TU651_001437"
     CDS             complement(14738..16165)
                     /locus_tag="TU651_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0897421.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            complement(16184..16363)
                     /locus_tag="TU651_001438"
     CDS             complement(16184..16363)
                     /locus_tag="TU651_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL0897422.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            complement(16447..>16701)
                     /locus_tag="TU651_001439"
     CDS             complement(16447..>16701)
                     /locus_tag="TU651_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL0897423.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
BASE COUNT         4514 a         3676 c         2353 g         6158 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgtagttat
     1621 agtaatgttt tttaacttat ttaattcttt cttggcttta ataatcatag tttcttgcaa
     1681 aacagactct ttatcaaaga ctttgtctct gcttacaaat aaatgaatgt gcttcaaaac
     1741 cacttcattt aaaaacttct cacgaaactt tttaaagtac gctccagaag tccatgatct
     1801 tggaacgata aacaccaatt cgccattatc aaccaaattg aaacttgcca tctccataaa
     1861 aagaaaatat aaattcggtg atccataaca aatatcaggc atggataaag cttcattagc
     1921 catttttcca acctttaaat aaggtggatt tcctataatt acatcgtatt tttcaggttt
     1981 agtactcacc cccaacatat tgttatattc aagtgtttga cttgttatat agttatcttt
     2041 aatcactttg tattcaattt ttagtgatgt attcttactt atccacgata aatttgcatt
     2101 taacagctct aaaatatcat cattggtttc ataacaagta atttttatgg cttcaatctt
     2161 atcagtatca ataattcttt gaataagagc tgccgtaagt attcctgaac ccgctcccgg
     2221 atcgagtata gaaatttctt ttgaaaatga tgataaatca aataatgatg ccatgaaaag
     2281 agctgtttct ttacttgtga aaaattgccc atttttcttg cgaatttctt ttggcatctg
     2341 tttaatatat ttatttgtag attcaattac ataatcaatt attttcatca tccaccaact
     2401 ccataatttc atttacacca cagttcaaac tatcacatat tctgacaatc acatcagtag
     2461 taatattctc actgttcttc attttataaa aagtactccg gctaacttct gctttttcca
     2521 ttagctcaga atttttcata tctaaatcta tcattttttt aaatagcttt ttataactta
     2581 ttttcgacac gattgtcctc ccatgcatat gattttgttt ttatcattat atcatattta
     2641 ttcacttttt tcactacaaa cttcctttta cacaaacaca cgacatttag atagacaaaa
     2701 aagagtcggt gcagtcctaa gaccacaccg accatatatt tatctctcag cttctttgct
     2761 tgcgtctctc ttttcttttg gtttttcctt atcttcagac tgatatttct tgatagctcc
     2821 aagaacagat tctttctttt cttcttgtcc tttcatttgt tcctttgcct ttaagagctt
     2881 tgaagaaagt atccttacat tgctatgctc cttgccatta tcatcaatgg aagttctgat
     2941 ttgtccaaag agctttacaa aatctccctg cttaaagtct tttggaatat cactcttttc
     3001 tccataagcg gagcaattat gataaacctt atttccctca tcatctttag atacaacaga
     3061 gaaatttgcc accttaaagg cttctccatt cttgttttct ctttcagcta catcaacctt
     3121 tcctacaata tttccaacga tattgataag attatctttc tcttcctgaa catagggcag
     3181 gtcttttatt tgcccctgtt ctcgtaaatc ttcaatcatg tagtcaaatt cctcatgcag
     3241 taaattcaga ctgtcattgt ccatataagc gtcatagagc ttgtccaaag cactttcatc
     3301 attgatacct ttctccacgc ttataatcgc ttttacaaag tccttgtggt tatcatttgc
     3361 catatcttct atttgatttc tcattgtttt gtaatccatg ttttttatct cctttcatag
     3421 taaaagggag gttaccctcc ccttatctta aaaattcctg ttcttttgta gtttgttttt
     3481 cttctgtttt actttcttcc tgataggctc ttatctgtcc taaaatagat ggcttatcct
     3541 ctgatttttg tgaactttct tctttgctat gaaaattatc ctccacatca tatgttgatt
     3601 caaaatagtc gctgtcctta aagtcattat cgtaacggtc agtaattccg tcattatcaa
     3661 ggtctttaga aagcggatca tagaagttac cttcgtcatc aatatcaagt cccgttgctg
     3721 ctttcaaatc ttctgaatcc acataaacca gatcttcaaa agaggatagc tcaatctcat
     3781 ttttcatatt tcttagagtt tcattctctc ctttgttctc atagtcaaag ctctcagttt
     3841 ttatagatat atcatcaata tactgtgtcc atatcttatc ctctaaatta agctcatatt
     3901 gaatgctgtg tctttcatcc ggcgtgttgg tataggcaat tcctatatgc tttaagtcag
     3961 gatatagagc atcaaactca tcgtagctat gattttcttc atattctctg ttacagaaat
     4021 caataattgc ccttttaaca tcttctacaa ggggattatc atttctcttt tcttccacat
     4081 cacccatatc aagtagctta tttagttcag ccaagcgaag caccttactc tttaattcat
     4141 cagctttttc aaacggcttt tttaattcct ctttggcatt ttcaagctgc tctttggtgc
     4201 ttatgagctt ttcttcaagc ctctttaatt tctcaggcat tttctcaaga gcgttatcaa
     4261 gtcttgtaat attaccgtca gcacttgtgc caagctctcc tgaatgcttt gcaacaccgt
     4321 ttaagctgaa attatgagaa ttagtaaaga agttataact tgcttccaag tccatatttc
     4381 tgtacttacc gattacctta ctttcattga ttttaacctt tgaaatagct tcaagcaatc
     4441 tttctcctgc taatttctta tcggtaatct ttgctcctgc gatagtaata gaagtaaact
     4501 tttcctctcc gtccgcttta ggctctacat cagatatatc tttcttgaca gcttctatga
     4561 gcttttcagt tcttgcgatt tcttcaggat agtttttcgc cactttatcc tctaatctgt
     4621 aacggttgga cttatagttt gcttcaagca ttttaagttt cgtaacctca ttatccaaat
     4681 ccatcttttc tttaatcttc ggatcacctg tggcaagggc tttaatttct gcatagttaa
     4741 gtgaactttc atccacatct tctgccactc tgacaggtgt tttacttgtc ataatctgag
     4801 aaatgaactt ctgcttattc tctattgtct gccacaaata cgcatcaaag gtgttctccg
     4861 taacataacg atagatattt acttccttgt tttcattgcc ctgtcttaca attctgcccg
     4921 cacgctgctc taaatcggca ggacgccaag gaacatccaa atcatgaagg gcaatcagtt
     4981 tgttttgtac attcgtgccg gctcccattt tctgagtaga accaagtaat atcctcacat
     5041 ctcctttacg cacctttgca aagagttcgt ccttttgttt atcggaattc gcttcgtgga
     5101 taaaggcgat ttcttctttt ggtattccca ttgctacaag tttttctcta atatcatcat
     5161 agatgttaaa ttctccatcg ccttttggtg tagacatatc agaaaatagt agctgtgttg
     5221 acttatcttc ttttgtctta tcccatatac taaagacatt tttcacacag acattgacct
     5281 tactgtcagg attgtcaggt agcagaggat taattaaacg ctgatctaag gcaagttttt
     5341 taccatcatt agtgtagggt aggatactag cgaggtagtc attgcgaccc cttttccatt
     5401 atccccccac cgaaccggac atgatacttt cgcatcatcc ggctctccag taatttcatt
     5461 tcataaacgt gtatttattg aaccattatg tattgcatgg tgacaatccc gacaagtcac
     5521 tagcattttt cgacgtcttg ctgacatgat ttctttccac tttggaacta atttcccatt
     5581 gtgtttgttc aagtctgcta attttctgat atgatgtacc tctatgttct cctcacttcc
     5641 acatagctca cacttatttg cgagtaatcg cttgataagc tctgttcgac caccataaac
     5701 ttgatacgga gcatcttcta ttacagcttt ctttttatgc caccccacgt tgcaactaga
     5761 ggaggtttat cttctcgaga cacaactacc tgtaaacacg gcaccgttcg gccattcgtg
     5821 ctagttgtgg tagtcttata tttagctaac attttattaa tggatgactc atgtttaaat
     5881 gctaatgttt taaggagtga tgtttccata taccaataga cttttgagaa ccatgacaaa
     5941 ttttgtgcca atatataata ttgaactagc cctctatatt cttgttggta agtttgaacg
     6001 atactaaagt catcatcatg caataagtta ttacgatgaa tagctttacc atttttcatg
     6061 tattggcggc atttgctttc aataactgat gcaggtacaa ataatgcgat aacaccattg
     6121 gcactctgtc tccctttgtt atcaatataa tcattgacac gttgtgcttt tatctcatat
     6181 cccagaaatt tagctgattc tccagtcgca tgggtaatca aagtcttttc ttgagaaagt
     6241 tccaaagata acttagtatt taaaaagtct ccaatttgct tctttatagc ctttgcctca
     6301 gcttttgaac ctgtaaagcc tagaataaag tcatccgcat accgaacata tcttaatctc
     6361 cgatagctgg tatcataagt atcaactgaa gggagatttc ttctctcaac aattaactga
     6421 tgagcttttt tataatctcc tttatcctga tagcatttaa ttcttctact caaacgatta
     6481 taggctgagt ttgctttctg ctttttacct cttgtatatt gaggtatcag ctcttcaccg
     6541 acccacttat caaattgatg taaatagata ttagctaata aaggactaat aactccacct
     6601 tgcggtgttc cactaatagt cttgtgaaac ttccaatcat caagatatcc tgcctcaagc
     6661 atatttttga taagcctaat aaaccgacca tcctgaattt gtctagacaa catagtgatt
     6721 aatacatcgt ggtcaatcgt gtcaaaataa ctagagatat ctccttctat gaaccaacgt
     6781 gtccctttcc aagtctgaat ttcttgtaaa gctgtatgac accctctttt tggtctaaaa
     6841 ccatgagaat gttcactaaa ttgtggctca taataggctt ctaatatcat gcgaatcact
     6901 tcctgaagaa gtttatcact ccatactggt attcccaaag gacggtgttt tccattcttt
     6961 ttaggaatgt actctctcct agctggtctc cagtaatagg tttcttgtct taattgttca
     7021 ataatcatat ctattttttg aatagacatt ccatcaatcg tttcctctgt aacacccttt
     7081 gtcattgctc cattattcgg gtataacttt gcataggcta tcagatagag ttcacgatta
     7141 aatagtaact tataaaccct ttcgagtggt ttatcttgtt ttccacgttc atgaatgacc
     7201 gttaaaatag ttttggctgt acgcatccca cgcacctaat cctttctaac taatcgaaat
     7261 tacctgtcac ccttcgccat gtacaaggat ttcccttgct cggactacta cggtgactcc
     7321 gttaccataa gggtcccccc tcttaggcaa tcctgctatt cgttaaaaat gtacgttcta
     7381 gtaaccctta ggttcctcac tcattccttt attcatactt atcgtatgct cttttactgt
     7441 agaaagttat tcgtccaaaa tcacaacaac gaatatacag taacatcggt ctcagttact
     7501 ttccgatggg cgatgctttg cacctagtca gaattgaggt tcaagcagtt tagccttaac
     7561 cataggttac ggaacttgcg gcacatcaaa gcgttgtaac tcactcctta tccgctttac
     7621 taacatgcta ttgtcccctt tgggtttccc cgctaggtta gttagttgtt cctattattt
     7681 actttcaata atatccctct gtgagggaga tacattttta cgcttaacag cgcacaattt
     7741 ttagcatatt atctttgtca ggctctacca ccctatttct cacatcatct gctctttcag
     7801 aaaggctctt tagaatttcc ttttgctcct cacttggcaa ggtcttaatt acttcataat
     7861 gtgcctcagg tgttggaaga tttaacatat ccgctgtttg aatgtcagcg acttccttaa
     7921 acatagacat tagttcaggc aagttataga acttggaaaa tcttgtcttt actctgtatc
     7981 ctgttccctc cggagaaagc tcaaaagcag actgcgtttc cccaaaagta gaagcccagc
     8041 tatcaaaatg ctccagatta tttttcttta agctctcata ctgaagataa cgctgcatag
     8101 tgtaaagctc agtcatggag tttgatacag gcgttcccgt tgcaaagaca atgccttttc
     8161 cgtttgtcat ttcatccata tagcgacact tcataaacat atcggaggac ttaaaggctt
     8221 cactttgacc gattcctgca acattacgca tttttgtata aagatagaga tttttgtagt
     8281 tgtgtgcttc atcaacaaag agcttatcaa ctcctaattc ctcaaaggta atgacatcat
     8341 ctttcttaaa atcgtcattt aatttctcaa gccttgtttc cagttttttc tttgtctttt
     8401 caagctgttt tactgtaaag ttctgatttc tgtcatgctt gtattcttct acatagttta
     8461 cgatttcatc aatctgatct tggatatgct tctcctgata ttccttagac ataggaattt
     8521 tttcaaactg cgtatgcccg ataacaacgg catcgtattc tcctgtggca attcgaccga
     8581 taaaacgctt acggttcttc ggctcaaaat ctttcttatc tgccaccatg atatttgccg
     8641 acggatatag ctgcataaac tcacgaccga tttgtcctgt taagtgattg ggtacaacaa
     8701 acaaggactt actacacatt ccaagtcttt tactttccat tgcggaagcc accatttcaa
     8761 aggtctttcc actgcccacc acatgagcaa gcagggtgtt gcctccataa agacttcttg
     8821 ctatggcatt tctctgatga ggtcttaaat ctattttagt attcattccc tcaaaggaaa
     8881 gattacttcc gtcatattct ctgtttcgga tagagttaaa acgctcatta tacagtttta
     8941 caagacggtt tcttctctcc tgatcattaa atatccagtt cttaaattct tcttttagta
     9001 gttcctgctt ttgccctgca agcatggttt cttttttatt tagtacagaa gttttagagc
     9061 cgtccggatt tacaatctgg tcaaatacct ttgtttcttt caggtttaag gcatcttcaa
     9121 tcagcttata ggcatttacc cttgatgtac cgtaagtcat ttcagcgagg tcatttcctc
     9181 tatccctact tttaccttct atattccact cacttgtcag gtttgaaaac ttaaccttaa
     9241 tatcccatct tgcatatccc ggagttttca gcgtttcaaa aataaatttt tcaatatctt
     9301 taatcggtat ccaagtcgca ccaagacgaa cacttatctc acttgcttca agctcctttg
     9361 gtagaacttt tgtaagctca gccttttggt attccaaacg attcatctca tagctaatca
     9421 gctctttttc tttaccatct tctgcatagc caagatgagg taactctctt tccgtctgtc
     9481 tgagctttga tagatagcta tctactatgg caatcttgtc cctgatattc ccacttaaat
     9541 attcatcctt tgttacatag ccgtatttgt aggaattact gccattggca caggcaaaag
     9601 gcaaatctcc atcttcgggg ttaaaggata gaggtctata aaagttttgt tcttccctaa
     9661 tatttaagta gatttcccct cgaagctcct caatcaaagt cggtctgtct tttcctgtaa
     9721 gaccttccat atagtcaaag tccacatatc ctttttcaga taccgataag acaagggctt
     9781 ctaaagaagt atccacatga tctatgactt tagcctttgt aatagttctt ttggagaaaa
     9841 tatctccctt tgccttaaag ttttcttcat caaggatttc aatggaggaa acaagcggga
     9901 agttgctatc ctcttttaaa gctcttgtat tgcttaaatt atttacaaag ccatgcttat
     9961 tagaaaaacg gtcatagact tcatttagtt tttcctgtga agccttgatt tcttcctcac
    10021 taaaaccttc tttctgcttg taaatcacat tttttaaggc agcattcagc tcaagataat
    10081 ccttgatttt ttctttgttt ttatcggtta cttccttttt gataaacagt gagttttctc
    10141 tgtaatagac ttcatcatca ataatggtat aggaaaagtt cttaacatca tccgttgcag
    10201 ggattgaagt gatttcatca tctaaaagct ctatttcttc atacttggca tcttttgaaa
    10261 ttctttctcc tgcaatctcg atacgatcct ttaatgaagc catatttagc tctgtgccta
    10321 aataagatat cggttcacaa gttagagttt ttccaaatct tccgcttact tcacgcattg
    10381 agccaagtac ctgttcagga tgatcaacaa agtatttgtt atatacaaga ccgttttcat
    10441 cttccgcaag gtgtatccaa tcttcatcac gctctaatac gctatctctt ttctttaaga
    10501 agataatatc tgaggttact tctgtgccgg cagtaccctt aaaggtgtca ttaggaagtc
    10561 tgatagctcc taaaaactct gctcttgctg caagatagcg tcttacactt tcatcctttt
    10621 tatccattgt tccacttgat gtaataaagg cgataacccc gccgtttcta accttatcaa
    10681 tggacttggc aaagaaatag tcatgaataa ggaagttatt acgattgtat tccctgtcat
    10741 ttactttgta ttctccaaag ggaacattgc cgattgcaac atcaaaaaag ttattggaaa
    10801 aagaagtttc ttcaagtcct ttaatctgta tatcactttc agggtataaa agttttccaa
    10861 tcctaccgct tatactgtca agctctacac cataaaactt tgacttgttc atttcatcag
    10921 gaagatttcc tataaagttt ccgatgccca ttgatggctc aaggatattt ccgctcttaa
    10981 atcccatatc ggaaagtgtc ttatatacgc cgtcaataac agttttcggt gtgtaaaagc
    11041 tcgttagggt agattctctt gcagcttcat attctgcctg agataagttt tcctttagaa
    11101 agctcctcgc ttctttccac tgtccgcctt tttcttcatc gaatacatca gcaagtccac
    11161 cccagcctac ataccttgct aaaacttcct gagctgtact gtcaaactct ctttgtccac
    11221 tttcgatgcg actcagcata gagatggctt caaggttatt atttagcctt tcacttggag
    11281 ataacttgtc aggtaatgtt tcttccgtaa tcttgaagtt atgagcttct gctttcttta
    11341 tttcactttc tttagcaata gtttcaggct ttttatatgt cagattttca aataccctct
    11401 caagatcgct ttcaagacga taaggaatta catctgagcc tgttatcata ccgccaagat
    11461 attcggtatt atccttaacc gttaccgtct ttagattatt tcccatatcg tcaaagcgtg
    11521 tgatggtata gtctttatcc ttgtatttaa tttcatctcc aacgataaac gcaggtcttt
    11581 cagggcttac ttgtcttaat aaatcttcat tatctgtaaa ggctacaata gggatttgat
    11641 ggtttccact tcttcccgga tcaagccata agtcatatct ttctgtgatt ttattttcag
    11701 caatttccct tacagtatat tcttcatgat taaaatagac ggtatcgccc tctttaactg
    11761 caaattcatc tgaaatactt ttcttttctt cgttaagctc tacttcttcc ttctccttca
    11821 gataatcaaa tagtgtttcc tgaacaggtg ttgcagctac tctttcttcc acttcttcag
    11881 atatttcaag ttcttcttta tcttcaaagc taagttctcc gttaaagact gattgaagtt
    11941 cctgttcatc catctgcttt gcaagttctg tatctttaag ctctctaaaa gtctttggaa
    12001 aatcctctaa aataagcctt tgagcattta attctttcaa ttcttcaaga ttgaaatatc
    12061 cccattcagg ttcaaatcct aacacaagtc caaaggcatc accgctttcc ctatcatatt
    12121 ccgtcatata ccaagtccag ttagaacgga aaggaataat atatgctgca tgaacctctt
    12181 tatccgctaa agctacatct tcctgtgcgt aaagctcagg cactctttca agcatttcat
    12241 cagtcattaa gttttcagga ttatctttag aataatattg tagctctttt gattcttcta
    12301 cctctgactt actttctatt ttcttttctt catacagatt tttagaaagc agctcctcta
    12361 tacgctttgc cacacttgac caagtaagaa aaacatcatt acaattattc ttctgtaatt
    12421 taagcccctt tgcatcatgc cattcatcac ttcccattgc ccccgatact gcatgacttc
    12481 taccacctat gccatattcg tcttttagga aattagcttt ttcctgcaag gtatgatttt
    12541 ctttgaaaaa ctttgtaatt cgctcttttc ctctatcgac gccacttcct cttgaaagac
    12601 tttcaaggac ttcatcttct gtaatgaagg actttacctt cggaagctct gttagattgg
    12661 tactatattc ctttcgtgac agctcaagtt cctgtaacct ctgacaaagg ctatctacct
    12721 tgtgatagtg aaaccttaat acatttctgt tttctttgta tccttctaaa aacctgctgt
    12781 attctttgat cgtttccttt aggtagtcgg gattttttaa tgcttcagac aatctttttg
    12841 tttcttccgg aaagcctctt ccacttgttt tcaatagttc aaaatatcct tgtccttctt
    12901 cgcttaaatc atgcattaga taccataagg actctgaaat cttatctctt tcataatcag
    12961 gagcctcaga aatctctaca tttgtagcaa actcaccatt atcaagaagc tcatttatcc
    13021 tctttgcagc atcgctccag cttaaaattt gcgtagtatc ttctcttgca gatgtcccgt
    13081 aggctaaatg aatgccttta tccgaatacc aggaagatac ttctctttca tcaatgtaaa
    13141 atccattacc gcctctaaat atatctttta ggtattctcc taattcttca ttactttttc
    13201 ctttagaaaa ctcagcgata acaggaagtc tacttccatc gtgatttcct ccgttaataa
    13261 ggacagtatc tatatccctc tgagttaatg gaatggtaag tctcatctgt ccatatgaat
    13321 tttcgggtaa agaaaaagaa gccttttcag cttctcttat ctctatctca gtattatctt
    13381 ttaaattttt aatacttcct tgattgtcat ttccttcaga gctgaaatca tcgccccata
    13441 ctgcggatcg ttctcgtcct ctatcttcca agctaccatc aatttcggct tctctgtcct
    13501 cataaagtct atcgcctgtt tctgaatatc catcaggtgt cctgttagct tcctctcctt
    13561 gtatagatcc actaacatct cgaagtggct ctgctcctcg ctctctgaaa ggtaatccag
    13621 cctcattact gcgtaggtcg gattcggata ctcccttatg aagtccgtct gttcctccaa
    13681 gctgtttagt gtattctccc tgattttctc tattatctcg tccgtactct ccatttcgga
    13741 gaactcgctc attttcattt ctttcctgat catctcgtcg aagtacatca ttatctcctt
    13801 tctcaatttt ttctttaatc ctattatatc ctgcttcttt tcctcttaaa acttcttttt
    13861 gaagctcaag ctctttgctt ttttgaatgg tttcatcaat aatctttcca ctaatatccg
    13921 atacgatttc accaagactc ataagggaaa tgctatcaag cattgcaaag ttttccttta
    13981 gaagctcatt atccatagga tagtctacat taaatcttga agctactgca taactcactg
    14041 agtccctcac aaacttggta aaagatattc tatcctcatc agctattcta agctcattca
    14101 taaggctgtc tatcttttca tcaccgtaga gtctacttaa agaaaagata ttttctaagg
    14161 tgctttcact ttcctcatag ccctcgtttt ttatcatttc ctttaagaca tccctatgag
    14221 cttctttatc aaatctccaa agattgacct cattgacatc cctatttctt gaaaccgtct
    14281 gacttatatc aaagatatat gccacttttt tgtatgtgcc gtagtcctct aaaatgggga
    14341 tacctttttg tcctctcata acagtacggt taaagcgttc cctccaatag tcgaacttgg
    14401 cacaggctgt cgcttcagaa tttctatcat aaatacttaa ctgacttcta aagtcatatc
    14461 tttgattgtt tccgacaacc tttaggagct tcaggtattc tgcttcactt tgcaaaatat
    14521 tttgttttac aagctccaaa atgttatgaa aatcatttat tcgcattttt acctccttct
    14581 ttttccaaac aaaaaaggcg gttagatttt actctaatca ccttttgatt ctgtgtattg
    14641 caacttgctg caacttaaat ttcctactac aaatcctcat tttatggtat tcatagcacc
    14701 ctcttattta taaaaatctt tgttttgcaa cttaatttta ttcattcagt tcccagtgtc
    14761 cgctattacc acttcctaca tacttcagat tatctatttc ctttatagct ctttcgatag
    14821 tctttacgct aactccagct tcatctgcaa tagcctttct tgtaatccta tcattgcttc
    14881 tcactttttc tttaataaac tctgcgagag ctatcttatc gtgagcgaca tcgtgagcga
    14941 caccctgagc gacatcgtga gcgacattgt cgcctccaac cttttgtgtc gctatcttct
    15001 ttagaggaat aatcgttctg aatatatctc cctcctcaaa tagcgggttt tgtcctgaat
    15061 aaagctgtgt gtatttgtag gtatttcgca ttcctgaacc aagttcatcc gcaagaccta
    15121 tttctctaaa aactttagat atagcaggat ttttaggaaa tggctcaaac ttctgtaaat
    15181 ctaaagctcc catcccatga gccaagttgc tgttttcaac tgtaatcctc tcatcgtcaa
    15241 taatcatctt tgcaggaaaa ccacttgaat aatctctatg agccagcgta ttggaaacta
    15301 tttctctgag tatcctgtct cttgcattga cattgacaat tccgtccaag acaaataaat
    15361 cattcaagtg cttttgtcca aattctatca gtctgtcata gctgtcaatc agatttgtta
    15421 tgacaacatc tctatcatca tatctatcct tattttcaac cctgaatata gcatcagttt
    15481 tgtgttgcgg aagaacggac ataatagagt tatcttttcc aaataacaaa atagcagcta
    15541 atgtgattcc ttcacgcttt gtttccggat ctgtcagtat caaattggca cttctaagaa
    15601 gctcctcatt actcatattt tcccaaacat gatttttatt tcggaaaaca gccattttct
    15661 tagctttatc aatgacagaa gcatcaagaa aatcaatatc aagattcgga tataccttat
    15721 taacaaaata gcttccttgt tttcttgcat atagcttata tacaagctct gaatgatctg
    15781 tgatattgat gtccccttca taagacctat cccaaattct tccgttatgt ctgcatacct
    15841 gataaccttc aggaactctt atataaataa cttgtttccc ctcaatttca aaagtttccg
    15901 gcagcaaata aagtggtgga tacatctttt gcggattgtt gattgccgta gtaaattcct
    15961 taatcacttt atctacttta tcttcactaa caccaacgat ctctctttta tcatttgcac
    16021 caagtaaaat atgtccgcca tttctattgt tgaaagagca tactgtatca aagacatctt
    16081 tggttaaagc gttcttggat tctttaaatt cgacatctat tttttctccg gcttgaatta
    16141 acttcttaat ttcatctatc gtcatctgtt tatttcacca cctttatttc ttaatgtttt
    16201 cttcgataaa aacattggaa ttttgaattt caactctatc tttattaact acaaaagtaa
    16261 catagtctcc attttctaaa ttcaaaagtt ccctaatcct ctttggaata gtaacctgtc
    16321 cttttgacat aactttagca gtatctataa atgtatcttt catgactaat ccctttcgcc
    16381 ctacttttcc tacaaaagat tatagcactt ttaagatatt ttttctactc tgaaattagt
    16441 gtcatcttac ttactataag ttgaaaccgc ttcttttatc tcattttcaa tcgcttctaa
    16501 aaattcttcc tttgaagatt tcccttgagc aatatcggat aattccattt cccattttgc
    16561 ggtagtttct gccgacttaa agttatcagc tacaatcgct acaaggctta ttcctttatg
    16621 tgtggctata aggtttttct tatctctttc tacaaatccc ttaaagatta agttttcaat
    16681 aatccctgcc cttgtgaact g
//
LOCUS       DARYLD010000048        16516 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYLD010000048 DARYLD010000000
VERSION     DARYLD010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16516
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(262..465)
                     /locus_tag="TU651_001440"
     CDS             complement(262..465)
                     /locus_tag="TU651_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL0897424.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TU651_001441"
     CDS             complement(482..736)
                     /locus_tag="TU651_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0897425.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TU651_001442"
     CDS             complement(1478..1774)
                     /locus_tag="TU651_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0897426.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TU651_001443"
     CDS             complement(1781..2029)
                     /locus_tag="TU651_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL0897427.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TU651_001444"
     CDS             2289..4445
                     /locus_tag="TU651_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL0897428.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TU651_001445"
     CDS             4456..5814
                     /locus_tag="TU651_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL0897429.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TU651_001446"
     CDS             5914..6045
                     /locus_tag="TU651_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0897430.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TU651_001447"
     CDS             complement(6167..7501)
                     /locus_tag="TU651_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0897431.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TU651_001448"
     CDS             complement(7501..8250)
                     /locus_tag="TU651_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897432.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
     gene            complement(8877..9080)
                     /locus_tag="TU651_001449"
     CDS             complement(8877..9080)
                     /locus_tag="TU651_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL0897433.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(9097..9354)
                     /locus_tag="TU651_001450"
     CDS             complement(9097..9354)
                     /locus_tag="TU651_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL0897434.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU651_001451"
     CDS             complement(9675..11042)
                     /gene="rlmD"
                     /locus_tag="TU651_001451"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0897435.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(11039..12007)
                     /locus_tag="TU651_001452"
                     /pseudo
     CDS             complement(11039..12007)
                     /locus_tag="TU651_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            12071..12847
                     /gene="recX"
                     /locus_tag="TU651_001453"
     CDS             12071..12847
                     /gene="recX"
                     /locus_tag="TU651_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL0897436.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            13080..13613
                     /locus_tag="TU651_001454"
     CDS             13080..13613
                     /locus_tag="TU651_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL0897437.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            13863..14174
                     /locus_tag="TU651_001455"
     CDS             13863..14174
                     /locus_tag="TU651_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL0897438.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
     gene            15315..16516
                     /locus_tag="TU651_001456"
                     /pseudo
     CDS             15315..16516
                     /locus_tag="TU651_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT         5409 a         3691 c         2649 g         4767 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaagt aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctaaca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttgtcc caaactcata agatgtattg actttatgag
     8641 atgaacaatt tgttacactt gatttgatca tcggggttta gaaaaaatag tgaaaagaat
     8701 cctcataatt cgtgaaaaat ataatttctc acccaaaaat ccaattcaag attgtattta
     8761 taagaagtag catgattaaa gttatagaaa ttcttatcaa cgcttcttct tttttaacaa
     8821 caccaaatat caatagtata atcggaacta aaactaatac tactaataat attgttttat
     8881 aatccattga taatggcctg tcctgcacca acaatgcatc ctattcctgc acccaataca
     8941 tacaatggac cagagaaagc acctgtaacg attgctccac ctgcacaatg ccctgcaaca
     9001 gagccccaat taattttacc gccatttaca cttgccaaat caagctcata taacatctga
     9061 aaatcttcgt actgcttcat ggtatatact cctttcttag ttaaatctat tacctatcat
     9121 tccacccatg catgcaaaac ctcccccaat tgcaccaaca tgtgcaccaa caaatgcacc
     9181 tggaagtacg ccaatccctc ctgctggggc accccacaaa gccccacttc cagctcctat
     9241 taacatatat cctcccatgt ctttaagaca gtccttacca gaatatccac cttcaacagt
     9301 tgcaagagcc tctatattca taacatcaaa ttgattaatc gtttctgtat tcattttgaa
     9361 tacctccata acatattttt tctttatgtc gcgatcacga tttaagtata gcattctagt
     9421 atcatatttt ttctaaaagt cttaaacggt cgttttttca tcgtaaacgg tcattttcaa
     9481 tcgttttcaa ccgttcaaga caaaattaac taccattcag gattttcatt ggataaatag
     9541 ctattttttg gctctttgcc aacccactaa agctattaat aaaaaaataa gacagtagtc
     9601 acatttaggc tactgtctct tttatctaaa gccttgatcg gtaagaaaag agccagtctt
     9661 ttccaactaa tcgattattg ttgtggtttt tgtcgctttt gtagcttcac tacagcctcg
     9721 gtccttgctg tgtgtggaaa catgtcaaca gattgaatat atatcacatc atagacctga
     9781 accaagggta ccagatcacg agccaaggtt gaggtattac aggagacata aaccatttta
     9841 gctggctgat agtgtaaaat cgtttgtaat agcttgtcat ctagtcctgt tcgaggtgga
     9901 tctacaatca aggcatcagc tcggtagcct tcagcgtacc agcttgggat cagttcctct
     9961 gccttgccag tctcataata agcattgtca aagcccaatg cctgcgcatt tttcctagca
    10021 tcagcaattg cctctggaat aatatccata ccacgaacag atcttacttt gtttgcaact
    10081 gccagaccaa ttgagccaac accgcaataa gcatcaataa tatgctcctc agctgtgggc
    10141 tcaagcgcct gaaccacttg actatataaa acctctgtct gtgtgggatt aagctgataa
    10201 aaggctcttg gcgacagggc aaagctatgg ctcaaaacct cctcttgaat ggtctcctga
    10261 ccccagagaa tctcagtttt ggcgccataa atatcactcg tttttgaagt attgatgttt
    10321 aaagcaacag tcctgatttg tggaaatgca gcagtcagct cagcaataag acctgccagc
    10381 ctcacctctt tactgcttac aaaaatcaac tgaacctgat cactggcctg tgccctacga
    10441 accataactg tacgaattcc agctactctg cgttcattat agataggaat cctataccga
    10501 tcaagcagct gagtcacatg attaacaatc gcctgtgtta gctgatcctg aaccagacaa
    10561 tcatcaatgg caaccaagca atggctccct tctgaaaata agcctgcctt gacggagcca
    10621 ccaaacgaac gcgtctgaaa ctgtaatttt gctcggtaat gctgcggctc tgccattcct
    10681 aaggtatgac gaatctcaaa ctcttcatac cccttaggct taaacttttt taaggcctgc
    10741 cgaatgatgt catccttaaa gtagagctgc ttaggatagg ccagatgcat gatttgacag
    10801 cctccacagg tctcataaat ggaacaggcc ggcttcaccc ggtttttaga agccttatta
    10861 atcaccaaga gccttgcctc agcaaaattg cgcttaacag cagtcacttg acaaaaaacc
    10921 tcttctccct tcaaggctcc gggaacaaag accaaggtct ttttataaaa accaattccc
    10981 tcaccattaa tccccattcg cttaatctta agcggtattt tttgctttat tttgacattc
    11041 attcctgact aaatattact cctaatcgct taagccttgc tatcatctgc ttgccaacac
    11101 ctggaatatc aagaagctct tgagttgtcc aggccgaaaa atcctccaga gtatgaatcc
    11161 catactgatt aaacaaattg accttactta aaggaagatc aagctcctct agaaatgtta
    11221 gctcgccttc agccccttca aaaaattcct gaacataatg ctgcaggtaa tattgtgcag
    11281 tcatcaatag cggtaggata ttaaaaaagg caaggtaaat acttgataag ctgtttggct
    11341 cgtagctctc cagggcacca gcagctaaaa tatcatctat cggaaaggct ttctgtctga
    11401 caattgccac aaagtctggc accgtctcag caaggttagc caaaatatca tcagctagct
    11461 cttctctttc agctaatagc gctccaacca tcaaaggaac ctccatcaac agatctcctc
    11521 tatgataatc cttactgtca taaaaagcct ctgccatcgt aaaatcagac tttaacacat
    11581 aaagagctaa gatttcatac cttgtcccta agtgatcccc ttcatcgtat tgatgaattt
    11641 ctaagaggtg atgtaaagct ttttcataaa gaccattttg cttatacagc atcgccagct
    11701 caaatttttg agacaagtaa ggtctctctt caagattcac ccatcccata ggcttagaag
    11761 caagctaggc ctgatgctga cagtcttcat caaaggccaa atacttgatt aagtcatagg
    11821 ctctatctcc tgcaaagtgc tccaagtccg acaacaactg gttatccatg ctgtttaaaa
    11881 gagcctctaa gtcatcactg aaaaactctg tctcatgtcc aaagagcata tcatcttctg
    11941 catcagcttg gcgatagtgc tgtaagctaa caaccttatc tctatctttt ttatcttttt
    12001 ctgtcataat gccctttcaa tctattgacc atttatactc ttattttacc atttttgtta
    12061 taatgagggt atgaaaatca gtcaaattga aaagaaaaag catttatacc tcattaagct
    12121 agacaatggt gatagcctaa cggtcacaga agatacgatt gtcacattta tgctaagtaa
    12181 gcacatggtc atagacagcc aacaatggga ggacatcaaa agcttcgcac aattctcata
    12241 tggtaaaagc aaggccttag gttttattgc cttccaacaa aggagccaaa agcaagtcca
    12301 agattacctg ctaaagcatc agattagtcc tgatctcatt ccaagcatta ttgatagcct
    12361 aaaacaaggc aaatggattg atgatcagca atacgttgac acctatatac gccaaaatag
    12421 ccttactgga gacaagggac cattacttct caagcaaaag ctaatgctca agggaatagc
    12481 ctcacaactc attgagcctg tcctagcaca gactgatttt tcctctatag cacaaaaggc
    12541 tgctgaaaaa atctaccaga aatatcaaca caaattgcca agtaaggcct tgaccgataa
    12601 aatcatacaa ggacttctta acaagggctt ttcctatgac cttgccaaag gcattgtcag
    12661 tcaactaagc cttgagcagg atagtcagca catcgaagac ctgcttgatc aggaattcga
    12721 caagctatta cgaaaataca gtcgtcgcta tgatggctat cagttgaagc aaaagcttta
    12781 ccaagccctt taccgcaagg gctatgacag tgatgatatt accactaagc taaatgacta
    12841 tttctaattc taccaaggct gctgcaccga tttgacgcaa aagcttttag tcagcaacaa
    12901 agtagtccta ttatgatcct gtagctttga taatggttta gctagctcct caactgaaca
    12961 tcagatttct aaaaacttct ttaagcattt gtcagatcat attgtccaaa acagtgattt
    13021 attttctcaa ttatggtaaa ctatagagga taagtttaat tgtagaaagt tggtaaggca
    13081 tgaaattacc taaagaaggc gactttatta caattcaaag ttataagcat gatggtagat
    13141 tgcaccgaac ctggcgcgat actatggtac taaaaacaac tgaaaatgct ctgattggag
    13201 ttaatgatca cacacttgtt actgaaagcg acggcaggcg atgggtgaca cgagagcctg
    13261 cgattgttta ttttcataaa aaatactggt tcaatattat agcaatgatt cgagataatg
    13321 gtgtttccta ttattgcaac cttgcaagtc catacctgat ggacgcagaa gcgctcaagt
    13381 atattgacta tgatcttgat gtcaaagtct ttgcagatgg tgaaaagaga ttgcttgatg
    13441 tagacgaata tgaaatgcac aagcaagaaa tgcattattc acctaatctg gattttattt
    13501 taaaagagaa tgtcaagcta ttagtcgact ggatcaataa agaaaaagga ccattttcaa
    13561 aagcctatgt cagtatttgg tacaaacgtt atcttgaact gaagaatcgt tagtcgttgt
    13621 ctagcactcc accgagggtg ctttatttaa tcgctagtat agtatcacag ctgtaaactg
    13681 gactggcact tgcaatctat cagcatttgt tgtcaaattc atatcattaa ccactatagc
    13741 ttggcacaag cacagacagc ctataacacc aagtagcaat cagtatttat catcagctgc
    13801 ctagctagat caggcattca aatgacctca ttataacacc ataacaatag aaaggattga
    13861 caatggcatt tcaagcaaca aaaggacgat acgcaagctt tggcgttgca gtcagccttc
    13921 cacctgagct gattgatacc ttctgggaaa tcattgacca ttacctaaaa ggggtgtttc
    13981 ccctcaatac tgttctcacc ttcaggctaa ttaaaaataa aaaaaacctt tcttatgagt
    14041 acattgatca acaagctggg cttcggattg tttttgacta taacacacca tttaacgcct
    14101 tttaccccaa aacgctctat atcgtaaacc agcaaggaat tgaaacgatt ttattgcctc
    14161 acgagatgta ttgataagac ctcggacatc agctataaag tccttaccat tcagttgtag
    14221 ctcatcacat ctgctacaag caccaacatg agataatctt gtgtctttat cctagctctg
    14281 aatgctgtat agatattcag tcagccagat acatagcaat aaactaagct catgccggta
    14341 gaaatagtcc taacatgagc ttgacagttt tttcattctg taaatcattg ctaagcaaac
    14401 acatcaccta agccctattt cctattctgg gaaatggaaa tcttgataga acatcccaat
    14461 agtcccatca tattgagcta tatctatagg gtctgacatt ttgatatgtt atcatctcat
    14521 tttacgacaa tcactatagg ctttatgaca attggcatca ttgtcataac gattaaattc
    14581 tatatgacca aatggctagt aggaagctaa ttgctttgtg ttagcctcac ataggatctt
    14641 cacatacccc gtaatcttaa aagtagtttt aactgcacaa aacttataga acctaaaaat
    14701 caacaaacac actttaaagt acaaaaactt tgccctccct caaaaagctc tataatctct
    14761 gtagtcggta agcccactgt ggaaattata gtttttttaa ttgtacaaaa acaagcccat
    14821 atgacttatc atgaaatgca atcaaaccat cattagaaag actcatagga acaccttaag
    14881 cattactcag catttaaaaa acaatatcca accgttgact gttctaaaag ctcaccccca
    14941 catcgttatc aatcctaagc ttgattattc agttctctta tgccctcact acaaaggaaa
    15001 catgagcaaa caagacttcc aaaaagcctc taaaatccct atcttcgatt gccaaagctt
    15061 tccaacactg cttcaactca aaaaacactg ctttcagtgg aaagccagtt ctaaagtgag
    15121 ccttgctcaa actccttttg gttttaacat cacaaaaaag agcaccaatc tggtcctctt
    15181 tagacgttag ttaggctcaa taatttctgt agtgggtaag tccactgcag gggttatagg
    15241 gctttatgag tatcaaaaaa gtcccatatg acctataatg aaaagcgact aaactatcat
    15301 ttagaaagac tcatatggaa caatcacatg ttatcacaca actactggga attaaagacc
    15361 ctcatatcac attctccaaa gaaatacacg acatgaaaac tcataaggaa ttgaaagctg
    15421 tccttgacta cgatgcccca ccttgcccta actgccaaag tcagatgggc aagtacgact
    15481 tccaacggga atccaaggtc ccttttctcg attgcgcagg ctacaagact ttgattcgcc
    15541 tcaaaaagcg ccgtttcaaa tgtcagtttt gcggaaaaat tactgtcgct gagacttctc
    15601 tagtccctaa aaaccatcaa ataccaacca tcgtcaaaca gaaggtggcc cagcttctca
    15661 tcgagaaagt ctccatgacc gctatcgctg atagactatc catctccacc tcaaccgtca
    15721 tgcgaaagct caacgagttc acgttcaagt ctcatttgac ttatttaccc gaacatatgt
    15781 cctgggatga atatgccttt aagaagggca agatgagctt tattgctcag gactttgaca
    15841 ccaacaacat catcgctatt ttggatggac ggacgaaagc tgtcattcgc aaccacttcc
    15901 tgagatatcc tcggcaggtc agaaacgacg ttaaactcat caccatggat atgtttaccc
    15961 cctattacaa cctggctaag atgcttttcc caaacgctta gattgtcctt gatcgtttcc
    16021 acattgtgca acatttggga cgtgccatga accgtatccg tactcaaatc atgaactctt
    16081 ttgatcgaaa atcccacgaa tacaaggctt tgaaacgtta ctggaagctg attcaacaag
    16141 atagtagcaa acttagtgac aagcgttttt accgcccgac ttttcgcatg catttgacaa
    16201 acaaggaggt ggtcgagcgt cttttgagct actctgacga gcttagaaag cattatgacc
    16261 tttatcagct tctgcttttt cacttccagg aaaagcaagc tgaccacttt ttcggcctga
    16321 ttgaggagca gatagacagt agcaatcctc tctttcagac cgttttcaag acctttttga
    16381 aagacagaga caagattgag aacgcactgg atttgcctta ttctaacgct aaactggagg
    16441 ctaccaataa tctcatcaaa gtcatcaagc gcaatgcttt tggatttcgg aactttgaaa
    16501 actttaaaag acggat
//
LOCUS       DARYLD010000049        15637 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYLD010000049 DARYLD010000000
VERSION     DARYLD010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15637
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..1031)
                     /locus_tag="TU651_001457"
     CDS             complement(<1..1031)
                     /locus_tag="TU651_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897439.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
     gene            complement(1037..1891)
                     /locus_tag="TU651_001458"
     CDS             complement(1037..1891)
                     /locus_tag="TU651_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897440.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            complement(1958..2158)
                     /locus_tag="TU651_001459"
     CDS             complement(1958..2158)
                     /locus_tag="TU651_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0897441.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            complement(2531..3268)
                     /locus_tag="TU651_001460"
     CDS             complement(2531..3268)
                     /locus_tag="TU651_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897442.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            complement(4019..4324)
                     /locus_tag="TU651_001461"
     CDS             complement(4019..4324)
                     /locus_tag="TU651_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0897443.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            complement(4326..4664)
                     /locus_tag="TU651_001462"
     CDS             complement(4326..4664)
                     /locus_tag="TU651_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL0897444.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSLGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            complement(4692..5447)
                     /locus_tag="TU651_001463"
     CDS             complement(4692..5447)
                     /locus_tag="TU651_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL0897445.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            5708..6163
                     /locus_tag="TU651_001464"
     CDS             5708..6163
                     /locus_tag="TU651_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL0897446.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            6147..6797
                     /locus_tag="TU651_001465"
     CDS             6147..6797
                     /locus_tag="TU651_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL0897447.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            6907..7811
                     /locus_tag="TU651_001466"
                     /pseudo
     CDS             6907..7811
                     /locus_tag="TU651_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(8164..8439)
                     /locus_tag="TU651_001467"
     CDS             complement(8164..8439)
                     /locus_tag="TU651_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897448.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(8862..10412)
                     /locus_tag="TU651_001468"
     CDS             complement(8862..10412)
                     /locus_tag="TU651_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL0897449.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(11083..11643)
                     /locus_tag="TU651_001469"
     CDS             complement(11083..11643)
                     /locus_tag="TU651_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0897450.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(11621..12490)
                     /locus_tag="TU651_001470"
     CDS             complement(11621..12490)
                     /locus_tag="TU651_001470"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL0897451.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            12582..13853
                     /locus_tag="TU651_001471"
     CDS             12582..13853
                     /locus_tag="TU651_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL0897452.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(13889..14227)
                     /locus_tag="TU651_001472"
     CDS             complement(13889..14227)
                     /locus_tag="TU651_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897453.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(14327..15415)
                     /locus_tag="TU651_001473"
     CDS             complement(14327..15415)
                     /locus_tag="TU651_001473"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL0897454.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         4831 a         3442 c         2719 g         4645 t
ORIGIN      
        1 gccaatttta ataataattc ttgtgtacca aaggtttgta cggatacaaa tgttaacagt
       61 ttgttcatca aaccttctgg aaaaattccc attagaaaga ccggtgcata tacaataaga
      121 gcagatatac caaaagtggt tagaggagac ttagttagag atgaaactag tgcatgaatg
      181 cctgtcataa atatcaggcc aatatactga aacaccaata aatagacaaa cgcaatgcct
      241 aaggtcatct tttccgggaa agccataatg tttatcactg gatcaatcca atacaaattg
      301 agttgtaagc tagtgtccca gccgctaaaa ccaaaatagg tcgcaaagac agcaaagacc
      361 agaccactag caattgcaaa taccaaagta ctgacagcta tgctaactgc taatttagca
      421 agagtcaatt taccacgtcc aaaaacagtc gtcaataaga tagagttcat ctttttagat
      481 gattcccctg aaaataaagg agccgttata taaagacaaa gcataacaac aagaagataa
      541 gtactattgg ttacatcaaa caactgattc caaggagcaa aattacctaa cttcaactct
      601 ttcaaaggca gagcggaccc caactcttca cgtgatttga gatgaacatt gtcaaatgtc
      661 agagacttat cagtgctatt aatagcgata agcttatcag tagacttagg cactaaatga
      721 gagatagcat aatgtgatac cacactatat acacccttct tttttaggtc tgattgattt
      781 ttagcataat cattgaggat acgactaatc agatcgtcag ataaataacc tgtatgcttc
      841 tcagcaattt gttggttaat tgctacagct gcacgtccat gaacctgatc tgcagaagag
      901 ccactgatct gaccgttaaa aaaatgctgg taaaaaagac cacctacagc caataagacc
      961 actacaatcg caccaaatac cgactgtcgt cttaataatt ttttaaactc aaagggtatg
     1021 agagatgcca tagaattcac tcctttctaa aatgataaat gtagagatcc tctaatgttg
     1081 gtgacacagg atttgcctga taacaaggac tctcatcgct cacaacacgt aagatacgat
     1141 tattttttac aattttttca ttgacaacgg catagtcagt caaaaatgct ggtgcactct
     1201 ctgtagcaac aggaatctcc cataccttgc cgatcattgt ttgaactaac tgatcaacac
     1261 ttcctttttc tataaactga ccatgcttta gaaggattac ctcctttgca accgcttcta
     1321 catcagatac aatatgtgtt gataggataa taattttttg ctctgataaa tcactgataa
     1381 tatttctaaa ttttacacgt tcctttggat caagtccgac tgttggttca tctaaaatta
     1441 acagtaaagg atcgttgata agtgcctgag caatacccaa tcgctgcttc ataccgccag
     1501 aataagaagc aattttcttt tttctaacat cataaagacc taccagcttt aataaccgat
     1561 cagcttctac taaagccttt ttacgtttaa cattcttcaa agcagccata taaagaagga
     1621 attctaaacc ggaaaactgc tgataataat taaactgttg aggtaaaaag ccaatattct
     1681 ggtaaaagtt ttttggttgt tgttgatgat ttaaactaat ttctccacta tcaggaactg
     1741 taaactgact aatgatgttt aataaagtcg ttttaccggt cccatttgct cccaataacc
     1801 catacaagcc tggtgtaaat tgtgcagaaa tacgactcaa caccttttta cttccataag
     1861 atttagaaat attatctagt attaacaaca ttgtcattcc tcctaagtaa aaacccaggg
     1921 aacagcacca cttcgctgct ccccagatga ttaaccatta agcattatat actcgacaaa
     1981 cggtaccagg ataaagaatc atgtggttat cagcattttc ttgtgctgta tctcttaata
     2041 gatgccatgc acttgtataa ccatcagtgc atctccacct ataaccccaa ccaccttcaa
     2101 cgcctgcaag catatcagca gtcattgtac taaattgttc aattgttttt gtattcatat
     2161 cgaatacctc cttataatga ttttatctag ctacagtctc gacaaactta gtgtagcgct
     2221 ttttaaagca acgacactca aaaatcttga atggttctta ttttgtcgtg aatggtcaat
     2281 ttttcttctg aaattaccag ttaagatcat atggatacct ttcacgagct atatcttttt
     2341 ctctcttttc ttatgatata attgattttt gcatgtacat catatctctg agcatcatta
     2401 gaaaccaact gttacccctt tttcttagtt ttgactaaat atatttataa taaatatccc
     2461 ttaaggtaaa tggtatcaac gaggttgatt aaaaaacaaa tgatggcttc cacatggcat
     2521 tcttttactg tcaatgcaaa gccttaatag acgcctcaag tgctttcatt tttagtcttg
     2581 aaaccatgca agactgccca ttcttgaaat agagtaaacg cttatcacga tcaagaaacg
     2641 aaacattgta aggattgata acataagaac gatgacattg gactagtctg gaatcttgct
     2701 taagaacctc tgaaagaaag ccataaaatt ctattcgctc gttttgagaa tgcaaaatca
     2761 acttgtgagg agtactagag gtctcaatga acaataggct tgaaaaagga acctgcacct
     2821 gagccttagc cgttgcaaaa ataaataagc cctctgaggt tacattttct tgctcttcat
     2881 aagcatatat aatggctctt tcaatcctat ctgagaaatg tttcattgac aattccttat
     2941 cgataaaatc tagagcagac acctgataac gaaaagaaac tggcataagc tcagaatgtg
     3001 tggtgacaaa aacaatgagg gcataagggt cacgctttct gatctcacga gcaacagcta
     3061 agcccttttt ctcatcattt cgaatttgaa tatcgagaaa gaaaagctga tgcctgcctc
     3121 tctctgtaac atttgccaga agctggtagg gctttccata aacttcaaaa cgatcacaag
     3181 tccagtgatg cttatccaat atctcttgaa tcttcatctc aagcctaaac tgttggccta
     3241 gatcatcttc gagaataaaa atattcattt agaacctcct tattgcttta gcttatcgtt
     3301 tttttaggag actaaagcag ctttttgaac aagtgatagc tagaacgctc tccttcatga
     3361 acagtatctt tttagcatca ccattaaaac catgaccgtt aagcttatta actaaaggtt
     3421 gtcaatgact tctaaccaac ttgtcattgc agcgttttca ataggcctta gcgaatcacg
     3481 cgcctcaaac aattttttta ccacagataa tatactagca cgagccgcaa gtcatacctc
     3541 tttgagagag agctcttaac gactatcact tttgtttgac aagtcatcag ctatcaatcc
     3601 acacactgat ctccttgcac agacattcta acacaaagct agggagcagg gagttaaaat
     3661 cttaaatggt actgattatg tcttaaatgg taaataagga aaactaacaa tggctagtca
     3721 ggttactgag gctatctgat gattagctgc ttgtagctat accttctcca agcaataagt
     3781 ttctagaatt attggtaaca aatacattag gtatccggga tattctgtca tttattttat
     3841 cataaaaaca atctttttat catcaaaaca ggtaattgtt attattatta atcactttga
     3901 gtgatttgaa gtaagctaga tcttcagcta aaccttatga cactaaacac aaaaagcccc
     3961 ctaaggcagc taaaacacca gcctaggggg caagattcaa gagagtcact ctatactttt
     4021 agaccatttc aatttgcagg tatttacaat ttgttgcagc ctctaaatga taaaactgat
     4081 gagcagagat actgatcaat ccgcctgctt tcatgtcatg agcctgatcc gtaagactaa
     4141 ccagcaacct tccttctaag acaagcagga gcttaccttc agggcttgat tcgttactaa
     4201 tcgtctctcc ctgatacatg gcatataaaa caacagattg cttaaagcct aggctttgat
     4261 gaagcgaacg actagctatt tggtcatcat gataccttac taattctaat aaatcagcca
     4321 acatgctaag cctccggctt tacaacaact aaaagcatct ggaaggcttc cttagcaaat
     4381 aagctatgag gaatattagc aggcatgatg atcgtctcgc cagcagctac ctcataacag
     4441 gcttctccaa tagtaatgtc aactactcca cttaacacgt taaccattgc atctcccagt
     4501 gatgaatgac gaccgatttc ttgtccttta tctaatgaaa acagggttat gcccaaatct
     4561 tttctttgaa ctagtgttcg acttaatatt tgatcctctt caattggcac ttctgccttt
     4621 aaatcaatga ctgtgcttgt tggaatttta cgaatcaatg acatgtcact tctcctttac
     4681 cattattcta gttatttttg acttacagcg gcaatataac acagctttct tccagttttg
     4741 ttgaagaaat gacgcatctt taaaaactgc tttcgatttt cttttttcat gccgcgcagc
     4801 ataatacgaa tcgcagcgac aaccccttca tctttaatca tgccaagcgg ggacatgagc
     4861 gtcatattac cataggagta attgactgct gtgaagccac tctttaccag caattgtctc
     4921 caggcatcta actgcaatgg cgatacgttc acattaatcg tatctcttag ttgctctata
     4981 atagcctttg tttcatcagc ttcataggaa acatcatgcg ttagtaggcg accacccggc
     5041 tttaaaacac gccaatattc cttaagtgct ttttcctttg cagcatcatt caacatggtt
     5101 agcatagctt cgttaataac gatatcaaag ctattatctg caaaaggcag cttcaaggca
     5161 ttagcttggg taaggtgaat atagtcttgc atttgtgctg cctcaatagc ctttcttgcc
     5221 tccgccagta ccttggtatc caaatctact gctgtaatat gacactgata agtctgcgcc
     5281 agctcaatgg aggtcgtgca acggttgcag gccacttcca agaccttgca atcactcgaa
     5341 aactctcctt gctgaaccag ccaattcgtc gcctcaacac cgccaggccg tagtcgtttc
     5401 tttcccagtc gagctaaaaa ctggtgacca acttcttttt gagacatcac atgccctcct
     5461 atttgctctg ctatatatca tcacttagaa taaactaact gttaacaaat tgatcaataa
     5521 atgattacta caactatatc acacttaaag catatcctca atgaagctta agcatttctg
     5581 atgattgttt ttatgataaa tcatagaatt ggctcatatt tcttgtgcta tacgaccttt
     5641 tgacttgcta ttatttttta aataatatat aatctagtta tcaaaactag ataaagaggt
     5701 tttagtaatg gaatatgata agctgcccag ctggaaggat ttacctgatt tggagttata
     5761 cttagatcaa gtgttactct atgtcaatca ggtcacacaa ttgagtcaag ccacagacca
     5821 taagctactg actgcttcaa tgatcaataa ctatgtcaaa catggctata ttgataaacc
     5881 tattaagaaa aaatatcaaa aaaagcaggt tgcccgctta attgctatta gcattttgaa
     5941 aaatgtattt cctattcaag atattagtca ggtcttgacg agcctacaag cagcctccag
     6001 ctcagaggtc ttgtacgata cctttgtcaa ctattggaat aatggcctta cccaatcaac
     6061 gcctgaaatt attagctatg cttgtcaaac cgtcaaggac tatcagcaca caatgaagct
     6121 ttcaagagaa atggaggata ccaagcatga accaaacctt taaacaaagt ctcccactat
     6181 cagttaatga agaggtcgca aatagtgtga cacacgctat tggagcagct gctatgctga
     6241 tactgctacc catcactgct atttactctt accagactta tgatctcaag gctgccgttg
     6301 gagcatctat ttttatcatc agcttatttc tcatgttttt atcatcaacg atttaccatt
     6361 ccatgtccta tggaacaact cacaaataca ttttacgtat cattgatcat agcatgattt
     6421 atattgctat tgctggtagc tatacacctg ttgccttatc cttggttgag ggcttgttgg
     6481 gctatgtgat tatcatactc cagtggggaa tcacactttt tgggattttg tataaaattt
     6541 ttgctaaaac gattaatgaa aagttcagtc ttgcgcttta cattattatg ggctggttgg
     6601 tcgtttttat cctgccggtg attatccaaa aggccagtct gccatttgga atcttgatgc
     6661 tactaggtgg cttatcctat actgtcggcg caggctttta tgctaaaaag aagccctatt
     6721 atcacatgat ctggcacctt tttatccttt tagcctctgc tttacaggtt attgccatta
     6781 ttttctatat gctgtaaaaa gtagctgttg ctacttttta aacgcgagcg cttgcttacc
     6841 cccagacacc tggcttgatt catgctataa taaagggcag taaatagttg aagggatcaa
     6901 agcaatatga aaacggtaca tattttttac aatcctaatt caggaaaacc agaaaatgac
     6961 ctggctgaaa aggtcaagca ttatctgatt caaaatggtt tttctgaaga caaggttcag
     7021 attattaccc ccaaaaatgc tgatcaagcc tttcaattag ccaaaaaatc ctcacaggat
     7081 catattgatc tagtcattcc tctaggcgga gatgggacac ttaataaaat tattggaggt
     7141 gtttatgaag gtggtgctca ttctgttatt ggactcgtac cgtcgggcac tgtcaataac
     7201 tttgcaaagg ccttaaacat tccactccag ctaactgagg cacttgagac gattttatct
     7261 ggcacgatta aaaaagtaga tatttgcaag gtaaacaagg gctatatgat ttctagccta
     7321 accttgggtc tgcttgctga tattgcggct aatgtgacta cagaagaaaa acgaaaattt
     7381 ggcccttggc ctttttaaag gatagtatta agatactaaa acgaaaccgc acatatgcaa
     7441 ttagcttaat tagccatcat catgttcttc acttgaaaac caaattctta ttgattacca
     7501 caaccaatac tatagcaggt cttccatcgt tttcaccagg tgcacaagct gacgatggct
     7561 tgtgtcaagt ttacacgatg agccagctat catttctgaa atgcttgcgc catattagag
     7621 actttagacg gggggatttt tccaaggtaa aggagattag ccattttcaa gctgattctc
     7681 taaagctatt gccacaatat cagcgtcaat cagccattcc tagaactcgc attgatggcg
     7741 ataaggctga tgatctccct gttgaattga aggttattcc aaaagcgatt tccattattg
     7801 ttagccagta aaaaagtgcc ctagggcact ttttgatata gattcatctc caagctgagt
     7861 tttagaaaac taagctatag ctataacgtt agctgtggct tcttcttgct ggcttgcagt
     7921 actcttttct tgtcttaaca gctagctctt tcataatatc ggctttaaca aagaagctat
     7981 ctgactagtc cgatcttcta ttctcaggac aaacagcgag aaaggggatt ttctttgaat
     8041 cctagagaac cttagctatc tctgtgtctc attgtaagtg cagctctatt gactgatgcc
     8101 agctatagca ataagcccag tcgcatatta taaaggatta tcaggcgatt tagcttgaca
     8161 ctcttatatc tttattgctt cttctaaggt tcctttaata gctttagctg ctgaatgacc
     8221 acaggcatta gcagcaacct tagaggcttc taccttatca gaggctgtct caataagttg
     8281 tccacccttt tcttggatat aatggttcaa ctcctcaata gtttcagagc cttcctttaa
     8341 gagctctttc tttttggctg aggataagct taaatatgtc acagcaattg ctgctgaacc
     8401 aagaagtaat cctaagccga ttccatagct ttttttcatc atcaacccta ctttctatga
     8461 ccttccttaa tcatcttttt agctaatttt acagctggta ctactaaaag caccaattgt
     8521 aaaagatcca tatacttgat ttttcgtcgt tttttcacca tgtgctattt cctttttctt
     8581 gtttgcacca tacaatcgtc ttttattgcg cagtgccaga gactgcctga ttaggcagcg
     8641 taagctaaga actatcagcg tgtcagacta gtctagatac agctaagcac tagcttgatt
     8701 acgataatac ttaccgctag gccataagct cagctatcat caaatctaaa gtgacaacgc
     8761 tttttattta ttatattgtc attttactaa aatacacaat tatcgtcaat gcttttgctt
     8821 taggcagcaa aaatgcccaa gataaagacc ttggacatct gctacaatga cgttaattga
     8881 ttgaaatccc aaatatcagt tacccagccc tcataaaact ccggctcatg gcaaaccatc
     8941 aaaatagagc ctttatagac ttgcaaggcg cgttttaact cctccttagc atctacatct
     9001 aaatgattgg ttggctcatc taggattaaa acattgtgct cacgattcat taagagacaa
     9061 aaacgaacct tggcttgctc accacccgag agcccctgaa tctggctttc aatatgctta
     9121 gaggttagac cgcaacgagc taaggctgcc cgaacctctg cttgatttaa agcaggaaaa
     9181 gcgtcccata ctgcttctag tggcgtttga cgcttaacac ctgcagtttc ttgctcaaaa
     9241 taaccaagct ccacgaaatc tcctgtttcc acctctcctg acagtggctg aataatgcca
     9301 agcaggctct ttaggagggt tgacttacca ataccattag caccgataat tgcaactttt
     9361 tgatgacgct caaatgttaa gttcaaggga tcttttgtta ggggtctgtc atagccgatg
     9421 acaagctccc ttgtttggaa aataaagcgg cttggtgttc ttgcttcctt aaactcaaag
     9481 cttggctttg gtttttctgc ctgaagctca atgatttcca ttttatcaag cttcttttga
     9541 cgggacatag ccatattgcg agtagctact ctggccttat tacgattgac aaaatcctgt
     9601 agctctgcaa tctctttttg ctgacgctca taggctgcct ctagctgagc ttttttcatc
     9661 tcatagactt ccttaaactg atcgtaattt ccagaatacc taaccaaatt ccgattatca
     9721 acatgataaa caatattaat gacatcattt aaaaaaggaa tatcatgtga aatgagcaca
     9781 aaggcattgt cataatgctg taaatagcgc tttaaccact caatatgctc agcatcaaga
     9841 taattggtcg gctcgtccag cagcaaaata tctggcttct ccagtaacag cttggccagc
     9901 agaatcttgg ttctttgccc tccagataag gaggtcactt ctgtttccat cccaaaatcc
     9961 ataactccta aggcacgcgc aacctcatca atcttagcat ctagggtata aaagtccctg
    10021 ctttcaagac ggtcctgtag ctctccgacc tcctccatta aggcgtcgac atcagctgtc
    10081 tcctctgcca tagacatgta aatggcattg atacgctcct ctgttttgaa tagctcatca
    10141 aaggctgtcc taagaacatc acgcacagtt tgaccaggtt ctaaaacggt atgctgatcc
    10201 aaatagcctg ctgtaacata ctttgaccat tcaatcttac cagcatcagg ctgcaagtga
    10261 ccagtaacaa tactcataaa ggtggacttg ccttctccat ttgctcctac taatccaata
    10321 tgctcgccct ttaaaagacg aaaggaaaca tcttcaaaaa tggcacgatc accaaatcca
    10381 tgacttaact gcttaacttc taatatgctc atgattactt tcctttattg tcatcaaaaa
    10441 agccgttaaa acggcttaca ctctctcaat tatggcaaaa atgcagcctt ttgtcaatga
    10501 aggctgaaaa agcctacgtc atacgcatga aagattttta gcaagaacag aaggtttttt
    10561 gcattttaat gttcagctat ttcaaatatg tcttattatt ttataaattt tactataggg
    10621 aaagccttga aagtgcctgc tttaatttat actatcattc ggaaagaact gtttcgctcg
    10681 tttgttgtgg aaagccgctc acaacaaaga catagagagt ctatgacaac aagagctaca
    10741 ctttagcaag tcttgaccga catgctttat tgcccagtct aattcattaa aaagcgaaca
    10801 ggtctagctt tcggaatttc agaaaactag gcctgttcat ttgttctatt ttgaggcagc
    10861 cttttgtttc ggcctcgtct gtttcaaggt tttcagatcg aacttaagga caaaaaacac
    10921 tctcctgtat cagctaacct tatcattcat tataaaggaa aatgatttct aatacaagga
    10981 aataccgtta tttcattaaa aataactaaa aatagtttgt caaatcatta gttattaata
    11041 ggcttagata acaaaaatga tgatactgct agcaaggtta gctcaaccaa gcctattact
    11101 cgcttcttgc ttttttactg cctgccttaa ttgcttaaaa acagggtata agagaggcac
    11161 agcaataacg gtcacaaggg cagtaccaag actgccacca attttgccaa gtgctgccca
    11221 caaagcaaca gacaggggta actgggcgcc aaaataagca atcaagctat atttcacaag
    11281 attcatgact aattttgctg ctgctgctaa taagccaatt gctacaataa tcatcggttt
    11341 atcaactgat ttcagaagtt tctcataaat cacatgaagc aggtaacaaa ccactaaggc
    11401 ttcaagcact gttatccaga ccacagccgc atagccatta atcatatcaa acagtcctag
    11461 accaatggct gccaccaaag ctgcccttct agcaccatac aataaaacag ccaccaccac
    11521 taaggcattc cctaggtgaa taaattgggc tccaactgga atacgcagca gctcaaccga
    11581 tataaaaata agagcagcaa ataggctaag ctcgatctga tcagtcaatc gttttgatgt
    11641 catctttttc ctccaataat cctctaaacg cggctcccaa gctgcccaat tctacttcgt
    11701 aggcaattcc aagtgaaagc tctcgattta gcgcaacagt agccgctaat gacttgtcta
    11761 agaagctaat aaccatatcc aacaactcat caatagcaag cctgtgaaaa tacccagcgc
    11821 taacaatagc agagacaaga tcacctgtcc catagaaatg ataagggtac cgttttccaa
    11881 aatgatagct aaccgtctct gttgcctttt gataataagc aaagccgatg tgctgatcat
    11941 caaaggatat accagtaagg acaatctctc taggtcctag tgtagctagc ttagacaata
    12001 gcctctccaa atcctctctg ctataggtct ccccaaaata aggaacatca gctaacaaac
    12061 aagcttccgt cacatttggc aatatcagct gtgcagcttg agcgagcaat ctcattgccg
    12121 ataagtgctg cgaggttaac tgcgcataca tgcttccctt gtcagccata ataggatcta
    12181 gcacaaaggg aagctgttgc tttttgatgt aatcaagaat aatcaaagca tcatcaggac
    12241 ggtacaaata accggaaaaa aagccatcaa aggcaagacc cgcttgagac caagtcgtca
    12301 aaaatggctt tagtccctct gacgtgctct gaatataagg cgtcttagca attgcagtgt
    12361 ggcttgataa caaacaggtt ggaagaatgg cctgttcaat ctggcaagcc gccataatgg
    12421 gaatactagc agacagagca accttgccaa ctccgacaat atcatttgca acaataacac
    12481 gttttaacaa ccaataagct ccttcatttc tttttttact attgtaagaa aatccttgat
    12541 gagatacaat aaggatagat ttcatctgta tggggacact tatgacaagt aaatatcaac
    12601 aaatcattgc agacctagag ttggccatgc aatcaaacca attcaaaaag ggagagaaac
    12661 tcccttctat tagacaatta agtcaacagt atcactgcag caaggataca gtgcaaagag
    12721 cacttttagc cttacaatac aagcgcctca tttatgctat tccaaaaagt ggctattatg
    12781 tgcttggtaa aattgaggaa aagcagcatt cctttgagct aagccttgag gattataatc
    12841 agttggccta tgaggacttt cggctctgtc taaatgaagc cctagacggt aaagattctg
    12901 atttatttaa ctactatcat aaggctgagg gacttgagga gctgcgagag gctttgctgc
    12961 cttatttggc tgataatggg atttacgcta acaaaaatca gctgctaatt acctcgggta
    13021 cacaacaggc cctttacatt ttagctcaaa tgagatttcc caatggccgc catcacattc
    13081 tccttgagac accgacctat caccgaatgg agcagctagc gacttcctta ggcttaccct
    13141 atcaaaccat tgaacgtgat gtcaacggta tcaatcttca tcagcttgaa agcatcttta
    13201 aaaccggaca aatcgctttt ttctatacta tttctcgatt ttcaaaccct cttggcctct
    13261 cctacagcaa aaaagaaaag gaaagcattg ttcggctggc agagcaatac caggtttaca
    13321 tcgtagagga cgattatcta ggggactttg catcgcatag tgagcttccg ctacactact
    13381 acgacactca acaccgggtc atttatctga aatcattttc aatgagcgtc tttcctgccc
    13441 tgcgcattgg agccttgctt ttacctgatg atctcaagga aggctttttg ttacaaaagt
    13501 caatgattga ccttgatacc aacctgatca tgcaaaaggc actagcatta tatttagcaa
    13561 atggtatgtt tcaaaaaaac ctaaagcaaa tgaggcaatt tttcaacaat agagcgcata
    13621 acttactaga ttttctacaa aaacaccttc ctaacctagc ttatcagctc actcctcaag
    13681 cactgattat tcaattagat aaagcattca atcgcaaaaa gcttcttaaa ccacaccaca
    13741 cccaaatcat ctcaacaaga aaagcaaggt atatgcttct aacaatcagt cctgatatgc
    13801 catctaagct gctcgacttg ttttcagtga cacatgaaaa gacccaagaa tagctcattg
    13861 ggtctcagtg tcacaaaaat gtcaatagct atttgatttg ctcgaatcgt aaatgaacac
    13921 taatgctatc gccgtaaccg tttctctcca aatctctttg gagccggtaa gcaatataat
    13981 gctctgcaat agtcatgtag cctgcgtcaa tcagacgatt ttcaacaagt gattgaatca
    14041 tattaatcgt cggacgctcc gcctgcacct cttctagatc aataacaacc tttttagtta
    14101 cctgagctag atgctgtctc cagctgtcat caatcacata aactgttctt gctgccttga
    14161 tcaaagcctg ataaatctta tccggatcaa agtctgccag ctgaccgtca cgcttaataa
    14221 tttgcataag agcgcctctt ttcatttagt ttcattgctt acattcatta tgcaaatgtt
    14281 ttcatcattt gtcaagctat taggctccta tgcctcttag ggattatcag tcaaaagaaa
    14341 cactaggatc aaataaattg tcctgtgctg gtcggacaag cccacgctcg tgcaaggtct
    14401 ctgcaatctg aacagaattc caggctgcgc ccttgagcag attgtcagat accacccaca
    14461 tgtgaatgcc cttttcaaca tctaaatcct tacgaagcct tcctacaaag gtctcacgac
    14521 tgccaacagc attaacggcc tgtgggtatc gttgcactcc ggtatcgtcc tctaaaacag
    14581 cacccggaaa ttgtgcaatc gcctccttaa cagcttcgat agtagctact gccttggttt
    14641 caatgtagat agattctgaa tgggctgata aaacgggtat acgaacacag gtcgcagaca
    14701 ccttaatcgt atcgtcctcc atgatttttt tcgtttcatt tgtcattttc atctcttcat
    14761 aggtgtagtc attttcagtg aaacgatcaa tctgtggtaa agcattaaaa gcaattggat
    14821 aatgtctctt gtcaccagct gacggtaaaa cacttgcctc cacctcctta ggagacaagc
    14881 cctggttaat aacctggtca tactgagcta gggtctcacg aatcgctgat tgaccagcac
    14941 ctgaaacagc ctgataggtg gaaacaataa tacgctcaag accccacctt tgacgaatag
    15001 gctccagcgc tatcatcatt tgaatcgtag agcaattagg gcaagcaaca aggccttgat
    15061 gtgtatcaag agcgtgagca tttacctcag gaacaacaag tggaacagct gggtgctgac
    15121 gaaaataaga ggtattgtca accacaacag cacctgccgc aacagcataa ggggcatatt
    15181 ttgcagaaac attgcctcct gctgaaaaaa gggctagatc aatgccttgg aaggctgctt
    15241 ttgttagctc ctcaacaaca aaatcctctc ccttaaatga gaggattttt cctgctgaac
    15301 gtgcagacgc taataattta atagctgaaa taggcagact tgactcctcc agcatcttaa
    15361 tcatttgctg accgacagcg cctgtcgctc caaccactgc tactgtatac cccatagatc
    15421 gacctcactt taactgatga tattgcaaaa aatgatattg gacctattat agcctatttc
    15481 atcacaaaag aaaagcaagc tagaagccag aacaaacgca tgaagaaaat catttattga
    15541 aaaagttgtg aaaatagcaa aatatccatt ttagagtatt ttgacagagt gtttcctgaa
    15601 tttttatatt tttcctctat aaacttttct tgaaaaa
//
LOCUS       DARYLD010000050        15122 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYLD010000050 DARYLD010000000
VERSION     DARYLD010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15122
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(461..2872)
                     /locus_tag="TU651_001474"
     CDS             complement(461..2872)
                     /locus_tag="TU651_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL0897455.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVKEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2887..3810)
                     /locus_tag="TU651_001475"
     CDS             complement(2887..3810)
                     /locus_tag="TU651_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL0897456.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4137..5684)
                     /locus_tag="TU651_001476"
     CDS             complement(4137..5684)
                     /locus_tag="TU651_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0897457.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6309..7190)
                     /locus_tag="TU651_001477"
     CDS             complement(6309..7190)
                     /locus_tag="TU651_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL0897458.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7355..8356)
                     /locus_tag="TU651_001478"
     CDS             complement(7355..8356)
                     /locus_tag="TU651_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0897459.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8497..9669
                     /locus_tag="TU651_001479"
     CDS             8497..9669
                     /locus_tag="TU651_001479"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL0897460.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9673..11157
                     /gene="galT"
                     /locus_tag="TU651_001480"
     CDS             9673..11157
                     /gene="galT"
                     /locus_tag="TU651_001480"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL0897461.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11167..12177
                     /gene="galE"
                     /locus_tag="TU651_001481"
     CDS             11167..12177
                     /gene="galE"
                     /locus_tag="TU651_001481"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL0897462.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12254..13297
                     /locus_tag="TU651_001482"
     CDS             12254..13297
                     /locus_tag="TU651_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL0897463.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13598..13741
                     /locus_tag="TU651_001483"
     CDS             13598..13741
                     /locus_tag="TU651_001483"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0897464.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14355..14516
                     /locus_tag="TU651_001484"
     CDS             14355..14516
                     /locus_tag="TU651_001484"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0897465.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
BASE COUNT         4356 a         3402 c         3023 g         4341 t
ORIGIN      
        1 tagttttgga catttagttt cttctttctt gcgaatgggt acaattgtac ggctgctaac
       61 ctttttccta acccttttag acaccaaaaa actcccctta tcgtttttag tgattgtttt
      121 tcactgtcca ctttaaaggg gaggtctagc tattaaaggc taggcggttt tgactggagg
      181 actattaggt gtgaggttaa ttggtaaaaa ctctttctgt gctgccctcc ttaggtcata
      241 tagactttct tggaaccaaa acccacatat agcctacaga gatccaatgc tttaaaagct
      301 atgaggtgct aagctgctga tcaagtcagc ttctctgact gttgctgcaa gcaaaagcct
      361 actaagcgat cttaggctgt gaggcgtaag aacaggtcat cataccaata gctttttggg
      421 gataagctgt gatttgtatg ccttagctat tttatagtgt ttatttgatt tgttgcaatg
      481 ttgtcacatc ataaagcatt aggtgtcctt tttggtcata gaatttgaca ccctctggca
      541 cgaaaataag atactccggt ttaatgcctg ctatttcagc taactgattg atctgacgtt
      601 caagagttgc ccgatctaaa ccataattag gaatatcgtc aaataaagac ttggtctgct
      661 ctatgccatc tgcggcagta tcttgcgctg acggttcctg gtctttggtt ggcttaatag
      721 tgctttcagc tgcgtctgag gtcttattgc ctaataattc ttgaaccttt tgccattcat
      781 catgagataa ctcatcttta gtaatggttc ttaaagagcg tccaccaact ctaggaatgc
      841 taaaggaatc attacgccaa acaaaggttc cttcagcaag aacgtcctta ggatcaaaaa
      901 tatagccatc tggagctgcg taccgacctg ccttgatagc tgcttggacc tcttcggcag
      961 agtgaataat ttgccagttt tccattgaag tacgttgatc agctggtgtg acattagcaa
     1021 tgactcctcc agcttcatca tgatttgggt tagaccaaac atcaggacga gtattagggt
     1081 gctgcatgac atatttgatg gtcgcaatct gatccttagt tagccatgaa taaggtacaa
     1141 catggatatg atcgatgtga ggaatgacaa aagatgtcca tgtatcatag gttgcattac
     1201 cagcatgcat cggtaggctg gatacctcta cagctagctt tggctgaacg cctgtatcaa
     1261 caatgtcata aatatagtgt tgcttatcct taagcatgag ctcttgctct gcaaaggcaa
     1321 tttgtgttag gtctaaatgc tcacgatcat agaaatactc tttgccatct tttgtcatca
     1381 tgtaaccaac cttaccgcca ttggttacct tgcgactgac atgcttagcg tcaaaggaca
     1441 tgtctttacc gtctgattga actaatgccc ttgcaatctc atctgcttga ccatgctcct
     1501 gcagccattg tgcaacctgg tcaagctcct cttgctctag ctcaccaaag cccatgtaat
     1561 ggaaatgctc ctcatgctta gctgtgatgc ctgccttatc aacagaggaa atagatgcct
     1621 tactaaagac ataatgatca ctcgtgtcat aaggcttgcc atctaagcct ttaccataag
     1681 ccttaatctg atggccaagg aattgatgtg taacctcttt tgcagtctgg tcttgagtag
     1741 ctggctttgg cttagctatt ggactgccct gcgtttgacc tgctaggtaa cgatcagcca
     1801 aggttatttc aagggctgac aattgctcac gaggaataat atggtagtga tctccatgag
     1861 gaataacata gccaaaggca ttggcaaggg tcacctgagt tggctcaaaa atgagaccat
     1921 cttccttgac gtgcctgtat ttcttatcca agccatgcaa ttgatccaac aattctccaa
     1981 aggttttatc tgcaaatgat aggcttggat ctcctactga cggcaaattc ccagctgggt
     2041 ggtgaatcgg gttaacagga atatcatatg gtctaggctg atctccttga cctggtaaag
     2101 gctgaccgcc aataacactt ggttttccgc cttgcttgtt attccaatag gcctgcgctg
     2161 ctactagctc acttggggat aagtcctttt taggaatata gtggaagtga ctgccatggg
     2221 gcactaaaaa ggcatctccc atgtctccaa taacatctgt cgggctaaag atatagccat
     2281 catcagttgt atagcgtcct tgacttcttg cttcgttaac agctgccacc tctgccttac
     2341 tcaagtgggc aaccttagcc aagccttttt ccttagcttc ctttgttccc ttttcaacct
     2401 gctcagcaat ttgctgcttg gtacgaatat ttttacgctt gcttcctggc tttagataaa
     2461 cataatactt gccatcaacc ttgataatat agccatctag aatctcgtta acaacatcag
     2521 actgtttaaa ctgataattg gggtccgtca ttaatagctc ttcactaaga atagcatcat
     2581 agggaacctt accattgtag aaatggaaat gatcaccatg tgaggttaca tagccttgat
     2641 ctgtgatttt aacaacgatt tgctctgcag agatcccctc ttctgcgctg atttgatcca
     2701 ttgttttttc tttggggagg gcttttttgc catcctttga atcaatatag gcaatgctat
     2761 tatctttaga tgaggaattt agagccttat gcattccaaa ctgatatgaa gcagcattag
     2821 tagccaataa aatggccaca gctgatccta aaacaatatg cttctttttc acgttttcat
     2881 ctccctttat tttaagcttt ggtaaagagc ttccaaatta gctctcaaat tgtctagata
     2941 ggacttgttg tttttgggcg ctgcctctag tggactgagc agcttgacct ttgctcctgc
     3001 tgttttagct atcgccttag caattttagg attaacatta tcctctgcaa aaatcgtttt
     3061 taccttatat tctttaacaa agtcttgaat ttcagttagt tggcgaggag taggctcttg
     3121 ctctggcgaa ataccagaaa tacctaactg ctttaagcca aagcgttttg ctagataaga
     3181 aaaggctgtg tgctgtgtga caaaggtttt agatgatgtc tttttaaact ttttagtgta
     3241 ctcatcagcc agctcttttg cttccttttg gaatgcttga gcattctcag tgtaaatggc
     3301 ctcatgctta ggatctaaac gactgagctc cttagcaata gcgagtgctt cttcacctgc
     3361 taaaatagga tctgtccagg tatgaggatc atacagggta gcagggtcaa tgccatctgt
     3421 cacctcaata tcctccaaac cagtaacacg atctaaggtt aaagatttgg aagcttcaaa
     3481 aacagcaacc tttgatttct tcaaattagg atccaaatca tcagcccagg cctctagggt
     3541 gtgagagtga taaacaaata aatcagcatc gtaaatggca gcaacgtcat ttacagatgg
     3601 ctcaaaggaa tgaatacctg cccctgactg aatcatccga acatcgttta gctcaccaga
     3661 taccgccttt gtcatggcgt aaataggata aaagctagtg acgatcgtca tgcctcttga
     3721 ctgcttgctt tgctccttgg gcttgctaca ggcaacaaga cctgaaaaaa gagcaagcaa
     3781 cagtgttaaa tgtatccatt ttcttttcat ataatctcct ttgctcatta accagttatg
     3841 aaccggttaa ttttaacagc tttagatgta tttgtcaaat tttttaataa aaaataaaag
     3901 ccattaaaac gatggcttaa tcagccccta acctgcttaa cctttataag aagccatagc
     3961 tctatgataa actgtggtct gtgacgcatg acctcactgt ctgttatctt actgttgcat
     4021 gatacgttta aaaaagattt agccttcttt ttttagattg tagaacggcg ctgaacaatc
     4081 acttaaccgt caaaaaaacg ccttgatagc tgcaagacgt ttttacttat ttggttttag
     4141 ctagagcgac gttttgtcac aagaccgatg acagctgcaa ggcctattaa tagaactccc
     4201 atgaacgcta ccatcggcgc tgctgattca ccagatcttg gcaaagcctt agtctctttt
     4261 ttaccttctt taggggctac attacggttt gacgaggact tggtttctgg cttagcgaca
     4321 ttcttatcct tttcaggatc ctttggctcc ttgcctaagg gctttgtgtc tttagaatgg
     4381 cgctcagact cgctgagttt attatcggtt ctgatttgag ctttggttaa aaagccgctg
     4441 acatcactac cggtagaggc ttttttaggt atcttgaccc cgttgataac aatctcataa
     4501 aacataccgt ccatgagctg attcacaaag gttgccttac ctgattgatc agttttgcct
     4561 attgccctga tagctccgta tcgatttttc agcacaacct cttgccctgc caacttattt
     4621 ccattggcat cataaacagt tactatggct ggtgtcttag agtaaacaac aggctttgtt
     4681 cctttaccgt cgacataaaa agcagcagcc ttatgctcat tagactcact cgtgcgaaca
     4741 gtatagccct gtagcttacc atcaattgag acactgatat tacgtgatag tggtagtttg
     4801 gtaaagactg cttgaccatc agcatttgtc tttgctgaag caattgtcgt cttagcaccg
     4861 tctatcagag cagtcaagct tacctccttg cctgcaacaa ccctatcctc tttatctagg
     4921 gcagtgacaa caaaatgaaa gccttcctct agcggacttg actttccatc ctcctgctta
     4981 ggagtgtcct tggactgagg tgacgtacct gatgacgagc ttgatgaggt atcaaggtaa
     5041 gcattaacag acatttttgt catgacctgc cctatatact taccattaag ctcataatga
     5101 taaaaggttc cgtccaacaa acgatccttg aaggttacct ttccattttt atctgagaca
     5161 agacttccca ccagttgacc ctgacgtatt tttagggtga ctgtttgccc ttctaagggc
     5221 tcactatctt gatttcggac cgtaatatca atgacatttt tactataaag aggctccttt
     5281 gtccctgctc ccttagcgac aaagcttgct gcctctttag atccagcaag actggttctc
     5341 actgtatagc ccttggtttc cccgtcaaca gaaacactca aattaatgtt taagggtaat
     5401 tgagtaaaaa tagcctgacc attgctgtta gagacagcag aagctacctg cttagcggga
     5461 ttagctgtcg tgtctaacaa gacaactgtt tttccttcaa gagcacgacc gttgctatca
     5521 agtatcgtgg caacaaaatc aaaaccctca gccgcttgcg acgtcgcagt gacaacgttg
     5581 tctctggcat aagtcgtata ggtattggca ttggctgcca aggccaagct agatataaca
     5641 gtaaccgtta aaagactgac ttttttcaat gactgtttct tcataaaaaa gctcctttat
     5701 tttgattaac tagcctagtt ttaatgggaa atatcccctt gatacccttt ctgaggtgat
     5761 aggaacagca gcaatctctc ttagcctatg atgcctaagc tttaaagcta agttttcaaa
     5821 gtccacctaa ggggctacat gccacaacaa aaagcatcag atgaacagac atctagaggc
     5881 aacagccgat ctaagataat agttagtagc cattttagct actctcaagg ctgtcgccgc
     5941 agtgatgatg tgattgtcta tgctttttaa taaaacttaa ctagttaaga tttttgtgct
     6001 gctatcctat caaataaccc ccgccaagtc aacaacaatg ctcataccac agcaagcaaa
     6061 gcattttgat gatgactgaa cagccaaatc agccaagccc caggcagcaa aaaagaggat
     6121 tcaaaccaaa tcctctctct actaagcctg ctgctgttaa cgtatcatgc taaaggcaaa
     6181 tggtatagcc acgctgatat gaaggtctga ttaacagcta cgacggacac gcttgttaag
     6241 gctaccattg ctaatcacac taggtcatat cctccaccgt ataagaatga ctaacttcat
     6301 tattcagatt aacgatatac ctgcaggtgc tgaggaagta ccttgacagt gattggtaag
     6361 gcctcaccct catcaccgtc cacattgata gatagctgtc cttccttcat ggcaatagtg
     6421 gcctccttga aggtttgata gccaagtgtt tgatctgaag cctcaactcc cttcaatagg
     6481 ctaggaaggg ccttcaccgt ttctaataga ttgctatcct tcagatagat aaggtgcagc
     6541 aaaccatcgt ccacacgtgc ctctggcaaa atccgctcaa agcccccgat tgaattggtc
     6601 aagccaatca agagtgttgt gctgttgatt tcttttgttt tgccatcaat atctagctgg
     6661 aaggtatagc ttttattttt gatcagctgc ttaaagcctg acataaaata agccattttc
     6721 ccaaaggtcg tcttctcctc aggggcaaca tcattgatcg cctctgggag cgtccctatg
     6781 gcaacaacat tcataaagta agcatcgttg accttaccaa tatccagagg actggttgtc
     6841 tcaaagctta tctgattaat cgcttcctct gggtctaacg acatgcccaa ggcacgtgcc
     6901 aaatcattga ctgttcctag aggaaaaaag ccaaacttag ggcgatagtc ctgctctgca
     6961 agcccgctga tcccttcatt gactgttcca tcacctccca tgacaaagac actgtccagc
     7021 cgctgctggg ctgcctcatg agcaaaccgt ttggcatctc ctcctttttc agtgtgctta
     7081 acgtcaacat catcaaaata cgaagctagt ttatcatagg ctaaggcttc atattccttg
     7141 gctttctcac cacctgagct agggttaaca atcaataggg cttttttcat ttatgatatc
     7201 ctacattttc tattatattt cacgactatt ataatcatta ttcaaaacat cgtcaaataa
     7261 tactcactat gtcattagtc agtcttaaag cttctaatat ggttgccgtc tagtgtttca
     7321 ttttactgaa ctctttaccc agctagctca atgcctaacc aatcgtgctg tctcttaagg
     7381 tcaactctgt cgccaatatc gtcatggtct tgacacgttc tgggttaagg atattcctat
     7441 taagcacatc aacagccata cgtcccatat cctctgtaaa tacagtcaca ctagaaagcg
     7501 caggaaagac ctgtcttgtt aaaggagtat cgttaaagga gataagctca acacgctcag
     7561 gcaccgcaag ccctctttct tggagagctc ttagagcacc tattgcaagg gtatcattag
     7621 caataaaaaa tgctttaggc aaatcatcac ctagctcctc aattgcctgt gtcataagct
     7681 catagccaga ttgtgctgaa aaaggaccga tatagacata cctcggctga taaatcccat
     7741 gctcagaggc ataattttta taggtgcgaa agcgctggtc cactaaagct tctctaccgt
     7801 cagttgtctt ttcctcacca gcaatcatgc caatgctata aatccctttg ctcataaaat
     7861 aatcaagaac tttcagcact gcattgtcaa agtcagttgt gacacagggg tggcccaatt
     7921 caagcgtgtc actatcaaca aacaccaaat gctgggataa ggcttcaagc tccttgattt
     7981 gacaagcgct aaactttcca atagcaataa tcccggcatg gtcatctgaa accctcaaaa
     8041 tgtcattgtt gaaataacga acaatatcat aatccaattc ataagctctt ttttcaatgc
     8101 caatgcggat cgcataatag tagaggtcat tgagctcctc ttcttgagaa taccattgaa
     8161 caatagctat ttttagcttt gatttagggc tattcgtcgc ttttaaatgc ttttggtagc
     8221 ccagctcatc agcaattgtg agaatgcggt gctttgtctc ttgaccaaca gacaagcttt
     8281 ggtccttatt taaaactcta gaaacagttg caggagaaac ctttgccaga gctgcaatat
     8341 ccttaagcgt taccatatca aaccttcttt ctgatttctt ctagtatatc acaagcattt
     8401 tcaaaagcaa tatttagtaa aattttagta aaaatgttga cgagcagctt agcgaagcgt
     8461 aaaatcaagc tatcaacatc gttaaaggag ccgctaatgg atatcgcgca acttaagcaa
     8521 agctttactg acgtttttgg caaggagcca gatgctgtct ttttctcacc gggtcgcatc
     8581 aacctcattg gtgagcacac tgattacaat ggtggacatg tctttccagc tgctatcagt
     8641 ctgggaacct atgggctggc ccgcaagcgt gaggatcagc agctgcgctt tttctcagca
     8701 aattttgaag aggctgggat tattgaggtt gacttaaatc agctgacctt tgatcaggct
     8761 gacctttggg ctaattaccc taagggagtt ctctcctttt tgcaaaaagc tgggcacctt
     8821 attgatacgg gctttgagct ttacgttttt ggcaacattc caaatgggtc tggtctgtcc
     8881 tcctcggcat cactggagct tttgacaggt attgtggcac aagagctgtt tgggcttgat
     8941 gtggaacggt tagatctgat taaaatcggt cagcaagctg aaaatcactt tatcggggtg
     9001 aattcaggta tcatggacca atttgccata ggcatgggag ctgataagca ggctctatac
     9061 cttgatacca acaccttagc ctatgaggct gttccgcttg accttggtga tcacgtgatt
     9121 gtcatcatga ataccaacaa gcgccgagag ctagccgatt caaagtataa tgaacgccga
     9181 gcagagtgtg aacaagccct tgaggaatta aatgcccttc tggatattaa agcactgggg
     9241 gaattagacg ctcagcgctt tgatgagtac agctacctta tcaaagatgg taaacgtctc
     9301 aaacgcgctc gccacgctgt tttggaaaat caacgaacac tccaagcaag acaggccctt
     9361 gaagcaggag cattggagca atttggtcgt ctgatgaatg cttctcatgt atccttggag
     9421 catgattatg aggtcacagg ccctgagctg gacacactgg tccacaccgc ttgggagcaa
     9481 gaaggggtcc taggggctcg catgacagga gcaggctttg gaggctgtgg cattgctatc
     9541 gtggctaagg ataaggtaga tagctttatc gaaacagttg gcaaggccta tactaaggtc
     9601 attggctatg ctccagcctt ttatctggct gagattgctc agggagcacg actactttca
     9661 aggaaataag atatggcaag cttaatagac acctttgtaa ggaaggtgat tgaacacagc
     9721 gactacacat cagaggacgc tatttatatc cgcaatcggg ttttagcatt ggttggtgag
     9781 aaccatgtct ggcaagaaac ctccttaaca gccttaatag ctctcaaaga agcattggtt
     9841 gagctagctg ctgaaaatgg caaaataggc aggcttcctg aagaaaagga ctgcttagga
     9901 gctgaattaa tgaacatgat aacccctatt ccaagtgtgg ttaatcgtcg cttctgggat
     9961 acctatgcac aatctcctca acaggctatc tcagattttt accagcttag tcagctaaat
    10021 gactacatca aaacagcagc aattgccaaa aacatctcct ttacagtgcc ttctcaatat
    10081 ggtgatatgg ctattaccat taacctatca aagcctgaaa aggaccctaa ggccattgca
    10141 gccgctaaga aggctaaggc atcctcttat ccaaaatgcc agctttgtat ggaaaacgaa
    10201 ggttatcaag gacggattaa ccacccagcc cgagctaatc atcgcattat ccgtatgagc
    10261 ttaggcaatg aggcttgggg attccagtat tcaccctacg cttattttaa tgagcacagt
    10321 attattttta atactgagca tgtgccaatg acaatcagta caagcacctt tagacagctc
    10381 cttgatattg ttgatatcct gccagactat tttgtcggct ctaatgctga tctgcctatt
    10441 gttggcggct ctattttgac ccacaaccat tatcaggccg gtcggcacgt ttttccgatg
    10501 gaaatcgcaa aacaagacaa acgctttacc tttaaaggat ttccagacat acaggctgcc
    10561 actctcaact ggcctatgtc agttatccga ctgcgcagca gcaacaaaga tcagctagtt
    10621 caattagcag acacgattcg actggcttgg cgtcattatt ctgacgacag tgttgatatc
    10681 gtcgcttata ccaaccaaga gcctcaccat accatcacac ctattgccag aaaaaaagaa
    10741 gggcagtttg aattagactt ggttctacgt gataaccata cctctgagca atttccagac
    10801 ggtgtttacc acccacatgc cgatgtgcaa cacattaaga aagaaaacat cggccttatt
    10861 gaggttatgg ggctagctat tttaccaccg cgcctcaaag aggaattggt tgaggtcaaa
    10921 aaatatatcc tcaatcaagc caatcaaatc gcagactacc acaaggactg ggctgatcag
    10981 atcacattac gaccagatct ctcagcgata actgttgatg acattatcca agaagaggtc
    11041 ggctctgtct ttgttcgtgt ccttgaggac gctggcgtct acaaacgtga tcaagaaggt
    11101 caagcagcct ttatgcgttt tcttaagagc attggcattg aagcaattga agaataggag
    11161 gaaaaaatga ctgttctagt tttaggcggt gcaggctaca ttggatcaca tacagtggac
    11221 tggctaatat cacagagaga agaaaaagtc attgttgttg atagcttggt gacagggcac
    11281 cgtaaagccg ttcacccaga ggctctgttt tacaaaggag acttagcaga caaagccttt
    11341 atgcgtcaag tctttaggga caatccagac atagacactg tgattcactt tgctgcctct
    11401 tccttggtcg cagaatcaat ggcagaccct ctgaaatact ttgacaataa cacagcaggt
    11461 atgattaagc tgcttgaggt catgagagaa gccaaggtta agcgcattgt cttttcatca
    11521 acagcagccg tctatggcat tccaaaaaca gtccccatct tagagtcagc gcctaaatgc
    11581 ccaatcaatc cttatggcca aagcaagctt atgatggaaa cgataatgac ctgggccgac
    11641 aaagcctatg gcatcacatt tgtggccctt cgctacttca atgttgccgg agcaaagcca
    11701 gatggctcca tcggtgaaga ccacgagcca gaaacacatt tattacccat tatcctacag
    11761 actgcacagg gagtgcgtga gcaggtgatg atttttggtg atgattatga cacaccagat
    11821 ggtactaacg ttcgagatta cgtccatcct atcgatttag ctgatgcaca cattttagcg
    11881 atggcatacc tgcgtcaggg caaaccatca caggtcttta atctagggtc tcaaacaggc
    11941 ttttccaatc gtcaactgct tgaagccgct cgtcgggtaa caggacaagc cataccagcc
    12001 aaaaaagctg caagacgtcc cggtgatcca gacaccttaa ttgcgtcatc agaaaaagca
    12061 cgcaaggttc tcaattggaa gccaagctat gacgatattg acaagataat cgcatcagcc
    12121 tgggcctggc ataccaagca tccaaaagga tatgacgata aagcaagtgg cagctagtcc
    12181 ctcaagacag ctaccacagc aagtagtcag cctcccttaa ttcatacacc tatactaata
    12241 ggagaaacaa actgtgaaca tttatcaaga catcattgaa tacatcgatc aagtgccagt
    12301 cacccagcta agactgatta atactaacgg tgttgaggct cacctattga cactaggagc
    12361 cactctacag gcctttctag tgtcaaatga aaagcagcca aaaaatatca ttttgggaca
    12421 tgaccgacca agtgactacc taaaaaatcc tctttgtgca gggcaaacca ttggccgagt
    12481 agcaggtcgc ataaagagag gaagctttca gctagagcag caaagggttt gtgttgacac
    12541 caatgaaaat gggcattgcc tgcatggagg cttcaagggc tttcataagc ttcattggcc
    12601 ttatgatacc cgccaaacag ttgattacct tgaagtaacc tttaaaaggg atattttaga
    12661 agcagatgac catttcccag gtgacctgac cgtaagcatt acctaccgtc tagacaacca
    12721 taatcgttta agcattcact ttaaggctca tagcatgaga ggcactagcc tattcaatcc
    12781 aaccaaccat gtttatttta atttagggca aacacaagac ttaaccaatc acaacctata
    12841 catcgcagca tcacatagga ttgaaacaga taatgagcta atcccaacag gtcaaaagct
    12901 agcagttgac cagacggtct atgattttag atcaataaag tccctctatc ctgctattgt
    12961 cgaaaataat ggctttgata ctgcctttga aattgatcag caggctattg gaacaaccaa
    13021 acctattgct gtcttacaag acagcgtcag ccatgaccaa atcagcatct actctgaccg
    13081 aaacgcactc gtcatttata ccatggacag tatccaagat ggcttgtatt ttggaagaga
    13141 tcagggcaag gagggactgg ctcgtgaggg gatcgctatg gaagcacaaa ccctgcctga
    13201 tgctattcac cacaaccagt ttggtgacat tatcctcaaa gaaggaggca ccaaaagcta
    13261 cactatctgc ctagcctatg agcatctgcc agattaacat aagtacagcc aagctttaat
    13321 gaaataacaa gaccttgatt tttttgaatt gcaccccaac cgttagccaa aaactctaac
    13381 aagcgaggat cagttcattc atcaaggtct tttcctcttt ttatctatag gcgttacaaa
    13441 gtagatatag gaacatcata ccaaatatgt ggaatgctaa gagcttatca tcacaaagcg
    13501 aatacatgtt ccgactacat ctatgcatta gtaagtcttt ttcctaaacg aagtgttgcc
    13561 agctttatga gatacttaaa agtataagag cagcctaatc atttttgaca aagacaccaa
    13621 ccttaagcat aaacataggc atcagaaatt ttggtatatg ggctattatg gagacacagc
    13681 tggtaaaaat ctaaaaacga tagccaaata tatttcaaat cactatagga agatagggta
    13741 gcaaaccaac tgacatcatt tgagaccatt gatccattta caggccaacc aaataagaaa
    13801 aagtaacctt ttgattgaac tcccgctcgg aaaagtggag cgcgagtatt caatgacctc
    13861 gttatcctcg accgatgaga gcagcttata gtcacagtat aaagaggctg gaacagacaa
    13921 cctcttttga ttgacaataa gtgtttgata gcattgtatg ggattacttt cacatcattc
    13981 agcacctggg tcgagctttg atgaccgcca gaattgatag ccattatgaa gggctttgag
    14041 cagccatttc tgctttatcg aaccataaaa tatcattgat gactgctcca aaaggacagt
    14101 cataaactgt ctgatcagcg cttctagtca cgaaccttta agcaaacctt aatactcaaa
    14161 aaaggtaagt cagaaaatac ttgatttctc agatgagctg tggaattacc acgaccttta
    14221 ccagctcttg ctctttcatt ttcaaaaagt gggtaaccga gtttttcggg ctgattgaag
    14281 agctttaagc ttggtcaatc atcacgtttt aaccgtcctc aaaatctttt tgaaatacaa
    14341 accctacatc acaaatgcct tattccaatg ctaaattgga gcccactaac aagactatta
    14401 aggacatgaa agagcaagcc tttggattta ggaactttaa gaacttcaaa gtcaagattc
    14461 ccaatgcttt aaacatcaca aaagaagaga caaaatttat ctcttctcgt gcttagctat
    14521 cagtcaccca ctgcagttga cattgagcca aattatagag ccattttcgt agaaagcaca
    14581 gaaaaaacac ccatgaggta aactcttgag tgctttgaaa cgttgatata atgcgatata
    14641 ttaacgtttt gaggcacgga gactgcgtct cctttgcagc cgtattcgta agcgactaaa
    14701 gccgcaacga ctacgtcaat tgcgtcgcca gttctttcaa aaaagaaaat accccatggt
    14761 aacccatgaa gtattgttct gctgtattgt agctggttct taacgttttg agaactgact
    14821 agctttacga gctttcttaa gacctggttt tgggtgacaa aaaccaaata tctgtaaaag
    14881 cttatcaaat caagctttca aaactcattt tcattaaata taagcacttt taacccaatc
    14941 ctacaaataa tagattacca ttagattacc aaaactcagt tttcggagct tatgtagttg
    15001 agaaaatctc gtatttactt tgcttttata tatccacttt atactatcat cccgtcataa
    15061 cagagcatga ttaaatagtt acataaaaaa caatacttac tctatcatta aaggatattg
    15121 tt
//
LOCUS       DARYLD010000051        14242 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYLD010000051 DARYLD010000000
VERSION     DARYLD010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14242
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(370..2049)
                     /locus_tag="TU651_001485"
     CDS             complement(370..2049)
                     /locus_tag="TU651_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897466.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(2224..7128)
                     /locus_tag="TU651_001486"
     CDS             complement(2224..7128)
                     /locus_tag="TU651_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL0897467.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            7481..8308
                     /locus_tag="TU651_001487"
     CDS             7481..8308
                     /locus_tag="TU651_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL0897468.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(8384..8737)
                     /locus_tag="TU651_001488"
     CDS             complement(8384..8737)
                     /locus_tag="TU651_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL0897469.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(8741..9253)
                     /locus_tag="TU651_001489"
     CDS             complement(8741..9253)
                     /locus_tag="TU651_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL0897470.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(9710..10264)
                     /locus_tag="TU651_001490"
     CDS             complement(9710..10264)
                     /locus_tag="TU651_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0897471.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            10475..11104
                     /locus_tag="TU651_001491"
     CDS             10475..11104
                     /locus_tag="TU651_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL0897472.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            11563..12648
                     /locus_tag="TU651_001492"
     CDS             11563..12648
                     /locus_tag="TU651_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897473.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            12834..14072
                     /locus_tag="TU651_001493"
     CDS             12834..14072
                     /locus_tag="TU651_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL0897474.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPQGERGEQGPRGENPTPTPDPMPQPMPD
                     PAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVL
                     GTGLLSLLGLGFLTRRKRKQ"
BASE COUNT         4135 a         3433 c         2840 g         3834 t
ORIGIN      
        1 ttctgaaaaa ccagtagata aggcatttta agcatttttt gatgataaga taatatcaca
       61 aaacattaat tatatgacaa ttattgtttt taattattag aatttttaat caaaactatc
      121 ctgcaatcag ctgtttagcc attttaaaag gcaaacaaaa accatgccac attgcaatga
      181 catggttttc ttcaagaaag gagcgagctt tggtttggta ctttctacaa ctgatctcca
      241 atagcagctg ctcctcgtta gtccctgagc cacaggtgac tgagctttcc tgcggctact
      301 ctgatagtac cagctactct tacaactgca taaagcagtg gctgccagcc aagctaaagc
      361 taaacaatat tactctgtta tagcttggtc tgctgacgag ctctcaatgg tcatgtgatt
      421 gaggtagttg tcatcagcca gctgagcctt aaactggtct ccgaccttta ggaaaggcag
      481 acggtcacta gtttcactgc ttgccttgat tttataaatc tgacccttgg aggaaatgta
      541 ataaaccgtt gttcctgaga taatctggct ggccaattgc tccacctgcc cagtaatcat
      601 cttgaccttc tgatcattgg tgtctgacac tgacagcgag cttgtgtcct tatctgtgaa
      661 ttgtgagatt aaggtctgaa tgtcattatt cactgttacc tgctgataat cctctgcatc
      721 aaccaaggca taggatttta tcagaccagc cccgtccttc aatgagataa ggtaataagc
      781 cttgtcattt aacttgacta gggttggtgc agttgcagtg tatttcttct cttgaacttc
      841 gccctcggct gatttcatgg cagaggcctc tgttgcagaa ggcagcttat agttagtgac
      901 ctctctggta cgcatgttaa ccaaaataaa gccgagattt gacgaatcag ctgttgctga
      961 ggtgattcct gtatagaggt aaatgtctga gccgatggta atgtagttat agctgtctgt
     1021 tgtttgcttg acatctgtct ggctaaagac agtgttccaa tagccctttt gataggtgta
     1081 atagtcatta accctctcca aaacattgtc agcagaatag acacgatcaa cccattttgg
     1141 aacgtccttt agctcatagt attgagactt gccgctaacc gcgtctaaca ggatcacacc
     1201 cgtcggctcc tgagaggaca ggccaaattt tggggcgtag gttgttgcga catagtaagg
     1261 gttaccatcg tcatcaacct caaatgacgg gtctgaaaaa atggtcatcg ggtactggaa
     1321 gcgcaaatgc ctcatggtgt ctctaaacat aaattccgaa tgagaatact tcataggctg
     1381 atttaacttg actagctctg ccttaccagt tgtctgattg accttgacat aatagccaat
     1441 gccgtcctta cgattggtta gccatttcca gaaggatttg tactccaagg gagaaacacg
     1501 ataagggagc ttgccgatcg taatctgacg gtactcatca gaaataccaa actgcgatac
     1561 cttatcaatg gtcccaagat aagtatctcc aatcttttca gccgaatctc gatccagcaa
     1621 tgccaaggct gacagatcag tgtctggaaa atccttgtta aaatcagcgt cctttacctt
     1681 aatcacatga gcataggact tagcacgaaa cattctagta ttaacagcta acagcaagga
     1741 caagccagca atgataacag caagggcaag accaagccac tttatgccac cggttaattg
     1801 cttgagtgaa agacctgagg tcacgtcctt gcggccagac ttttgcgtga aaaagctggt
     1861 cactgttttt ttcaacccaa acaaggacag gataaaaaga ctcaccatcg ccaagataag
     1921 cgcaagaatc acgaaaaacc aaaattctaa gctcatcacg ttcattggcg gcaaataaat
     1981 ccagtaaaag ccagccagga tcaagctgtc taagccaatc agcaccaaag aagcaacttt
     2041 ttttgtcata ctaatctcct cgtcacaccc taaggctatc aggggtattc aatatcttct
     2101 caccgctatt gtaccacatt tcccctcaaa agatgacatc tcagccagac atttttatca
     2161 gctcttagag cacctcagct agaatgatca atacagctga caggctacgc tcatagagct
     2221 tgcttagtac ttcttttgac gctggcaaga gcctgctgct ccaagactga gcaagcctag
     2281 caggactaga ttgaccgctg cttgctcacc cgttgatggt aggacttggg cttttttaac
     2341 tgcttgtgct gttagggcag agctagtgat tgatgagccg gtataatgag tcaagcctcc
     2401 agcctgatgt tctagctgag gctgcttagc tttgataacc tcaaaggtaa gctcaatcac
     2461 gccattatgt gatacctcta gacctccttg accgattagc tgatagccct ccggtagctc
     2521 aacgaggacc tcatagcttc cttgtcgcag tgttttacca taggcacttg gaacatagag
     2581 agacggagct agagaaatca actgaccatt tgctgctttc aggctgaccc tgctgccttc
     2641 tggcaagact tggttaaaca agagccaaac agaagccaca ataggccttg tcatctcaaa
     2701 ggcaactgaa gcaagccttg tatccgcatc tagactaaag ctaaccaagt tgtcagacct
     2761 tagctcaaac agatgattat cataagccaa gagctcaacg gtgtagcgtc caaatggcaa
     2821 tatcaagcta ttagctgagc tattgaaata gtccaactgc tcgattggct tgccctgctc
     2881 atcacgaata agataagtaa aggctggctc ttttttgttc tcaagcacat caagtgccaa
     2941 ggcaacggac actactccct tgtctggtcc tacagctcgc aaagcagcta agctcatata
     3001 agcaatctga cctgcctcgt cttccactag ataataataa tctgcttctg caacgccttc
     3061 aaccttagga atggtgtagg tgccgtctgc attttgagca atcatcacct tattatcctt
     3121 gaatctgatc agctgatctt cgacagttag atcaaacttg cgtccatctt tcttgacaag
     3181 gtagaagacc tcttctctaa caatacctat tggactttgt cccttgcttg gtcccggacg
     3241 aaagacctca gtagcaccat cagcttggaa gctagctggc gtaatgactg gcttttgatg
     3301 gctaactgtc accgcatagg cctctgcttg aggcatacca ttagcgtcta gataagaaac
     3361 aacatagcga taatgtcctg acatcaccct agctcctgag gctcttgtgc cataccaagc
     3421 ggtgctgtca acattagcca cgcttgcacc tggttggcta gaccagattg ggcttgtcat
     3481 agctgtatcc tcctgggcaa agaccgttac ctttagatct tgatatactt gatgtggcaa
     3541 gcccttgaat gccacaaaat ccttgtttcc atcatcattc ggcgagatga cagcagtttg
     3601 acctaattta gccaaacgac tctgtggtct attgcggcta ataatgagaa gctctgcttc
     3661 atttgtcacc agtcctgtat ctgcagcagt catgttgagg ttatcactgt agctcagctg
     3721 atgctgagca ttaatatcag ttagggtcaa tgccagctca gcctgaccga ttttttctgg
     3781 caagtgattt cccagcttag caatggcaac attgcctgca aaatcctcga ccatgtaata
     3841 aaaatcacca agcgccacct gatcaactgg caggacaaaa gagccatctg ctaagcgctc
     3901 aacaaactgc ttattgtctg atacggtcac atactttaag ccatcattaa tggtaatcgt
     3961 ataaggcttg tcatcctttg tttccaagta aaaaacacta tctcgaagaa caccagcctg
     4021 accgcgatca agccactgag acggtctgaa gcgatgggtc acagggttat agcttgctgt
     4081 tcctagctcc ggcgtttgac gatccacaat cacctcaaag accatttctt gacgtttcgc
     4141 tcctaccaca tctggataat aagaaaccac ataatggtat ttgccatctg gtaggtcagc
     4201 tccggtcagc gatttaccac taaagcctgt ttctaacagc gttgttgact tggcaaagcg
     4261 aatatcactg ttaaagtttt tatccccttg aagggctgat gggctcgtcc agagcaactc
     4321 cttacggtct gtatctgttc ccttatagac cctggcttgc aggccttggt atttacgtaa
     4381 gaacacccct ttgaaggcag caaagtcttg attgttgtcg ccatttggag agatagccaa
     4441 cacaggatag ccaactgcat ttcgctccaa cacaaattta ccgtctttat tacgaaaggt
     4501 tcctagtgtg tgcaagccat tgtcagcaat agtagtcata gagacattgg tatctgtacc
     4561 aacagtcacc agcccagtaa aatgattgcc gacataaatc tcgtccttta gccctgagct
     4621 gtcaaaataa aagccagttt ttccttgagc ctttagctca taaatagagg cttcaacaac
     4681 aggtaggttt tcaaaggctc ccttaaagcc aacaaatgga atgttgatgt tatccttgtg
     4741 ctcgtccttg ctatccacaa agcgaacaaa gccctctaga taatagccat ttggcatttg
     4801 cttagagagt tcctctgtaa agtttgaggc atctagggta atggtaatgg tcttgtgtcc
     4861 ttgagcaggt acgtcaacct gttctccctg ataggttttc agagatcttg aacgtaaggc
     4921 aaaacgtcct tccttagtat ccacctgatc agtcaacaat tctgtctggt agcgcagcga
     4981 cttagcctga ttagacaagt tatggattgt cacctcaaag cttatctgat cagtcacatt
     5041 tccaagagaa atactgccat agttgtcttt acctgtcagg tacagaccac tggttaccgc
     5101 ggtctctata ttcaagagcc ctgctccctg ctggcgtggc gatgtggtgg tattggtctt
     5161 agggttgatg tggatctgag cattactcat cagtatattt ttgaccagat ctgctagctt
     5221 atccttggca agctgtggtt gaagcgcttc tagatattgc ttgaccaaaa ggcttgcccc
     5281 tgcaatgtgt ggggttgcca tactagttcc tgactggctg ccatagtgat catcgttgaa
     5341 ggtcgagtaa atatctccac ctggagcagt gatgtcaggc ttcaaatagc catctgaggt
     5401 caagccccag ttagagaaat agttcatctc atttcccttt tggctaatgg ccttagagac
     5461 ctcagcatca aaggtcagag tgcctgttcc attgccattt aaagcagcca ttgccatgcc
     5521 aaattcatga gagataaagg cagatggcag caccatcccc tttgaactca gacgcatggt
     5581 gcggttagcc ttgcctggct cattgttaaa aatcaagacc ccagctgccc cgtactgctt
     5641 ggcctctgct ataatatcgt cgtatttccg attaggatca cgctgcacca agacaatctt
     5701 gccactcact tcgcgttctt ggtagccttc ttttgtcaaa gctttgacat aaacaaatga
     5761 gtatggtaca tcaaagccaa gactagtctt aatgtccttg aaatcaacag attccaaata
     5821 gatagccttt ccatgattta agtcagccct atctttcaag ccctccaccg tcatcagacg
     5881 ctctataatc actttgttat taatagacgc aactgaggta ggagtccggc ctgctgatgg
     5941 agcccccact aagccataat caggatttgt caccaacggg tctgcatgat ctgacccaaa
     6001 ggcacgctca ttacctgcag caacgaccac agagacacca gcctgccttg ccttttcgat
     6061 agctgccatc agggcacgat tcccattcaa ttgagaccca ttggccgagc ccagacttaa
     6121 attaatcaca tcagcgccca atgccacagc atcttcgatg gctttaataa ataaggggtc
     6181 cccagttccc atcaaatcat gggtaaaaac ccgcataaac atgacctgag cctcaggagc
     6241 aatgcctaaa aagcgttcgc cagctgctgc cgccttgagc ccatttccag ctgcaatgcc
     6301 tgtcacatgc atgccatgcg attcatattt gctgtcatca tctgtatctt gccagtcaat
     6361 gatagttcct cctgatgtgt catcaagctt gatgaccgtt tcctgaggtg cctctattga
     6421 ctgcggacgg ttcctcctaa tatcaatctg ctgcacaatc acatcaaaat ccaagtcgtc
     6481 aaggccctca aacggatcgt cctttatctc ctttacctta tcattgtttt ccacatagtt
     6541 gtgggcaaag actaccttat cgcttagcca gacaccgtac tgaatgcctg ctgctttttt
     6601 gcgctggtca atatctgcct ttgatgtaaa cttagcagct gctggatttg taatgcgcat
     6661 ggcatggtga ctagcgtcaa taccagtatc aataacagca ataaccttac cttgaccctt
     6721 atagcctcta ttccaagctc cttctgtttt tatccagcgg tgagtatcca tatttactgg
     6781 aggtagctcg cgcgattctt cttgctgctt gactgattgg ttagattccg ttagcgcttc
     6841 catttcggaa gaaactaatc cagtcgccat tgcctcctct gtcttttcct ctgctttact
     6901 tgactggctg tcgatgtcct gagcattaac agcagctccc tcactagcct gagagacaga
     6961 caatacctcc cttgattctt gatgttgtcc tgctgacacg tgagctgagc taactccctg
     7021 ctcctcagcc acaactgatc ccatccctgt cagaaaaagg attccgatca acacagaaac
     7081 cattcctgat ttatatttcc tcagtgagaa gcgttctttt ttctccactt gatgtcctcc
     7141 tagatttatt aaaaaaggtt attttaaaca aatgattcat ttatgtttta atcaataatg
     7201 tctaagctat ttaaccattt tttaatcaca aaagcaataa gactagaagc tctcagttta
     7261 tgtcattttt taatcattca actcactgaa atgaggcctc tcagaacctg tctcatcaac
     7321 agataaggct aaactcagcc gctagacttc aaaaatgtca caccattttt agacattacc
     7381 tgtcctcata cctataacag aaccaagctt ccacagtcgc cttggcctta tttttttgtt
     7441 acaatatagg ttaagattat catttagaaa gcgaagaaaa atgaaactca tctcatggaa
     7501 cattgattct ttaaatgctg cgctcactgg tgaatctcct agagccctct tatcacgcgc
     7561 tgtacttgat actctcgtgg cacaggacgc tgatattatt gcaattcaag agacaaagct
     7621 atctgccaaa ggccctacca aaaagcacct tgagagcttg cttggctact ttcctaatca
     7681 tctcaatgtt tggcgttcat ctgttgagcc cgccagaaaa ggctatgccg gaaccatgtt
     7741 cctctataaa aaagagctca atcccattgt cacattccca gatatcggag ctcctaccac
     7801 tatggacgct gaagggcgta tcatcaccct agaatttaac gatttctttg tcacacaggt
     7861 ctacacccca aatgccggtg atgggcttag acgcttggaa gagcgccagc tctgggacca
     7921 aaaatatgcc gactacctag cccagctcga tgcccaaaag cctgttttgg ctactggtga
     7981 ttacaacgtt gcccacaagg aaatcgacct ggctaaccca gctagcaacc accgctctcc
     8041 gggctttaca gatgaggagc ggcttggctt tacgaacctg cttaaccgag ggtttacaga
     8101 tacctttcgc tttattcatg gcgatattcc aaacgtttat agctggtggg cacagcgcag
     8161 caagaccagt aaattgaaca ataccggctg gagaattgat tactggctca cgtcaaatcg
     8221 gttgattgat aaggttagtc gctcagagat gatttcctca ggagaacgtc aggatcacac
     8281 accgatttta ttagaaattg atctatagac tagaagcatt cggacaaatc aacccagaca
     8341 ttaaaaaaaa atggctctgc aagagaaccg tttttttaat cgcttaaaga cctagatcct
     8401 tataggctgt tcgataccct acctgcaaga cctgattatc ctgtaagagg atcggccgct
     8461 taatcagcat gccatctgtt gccaaaagct ccgctgcctc ctcaacgctc agtgaattaa
     8521 ccttatcttt aagcccaagc tcacgataac gcataccact ggtattgaaa aagcttttga
     8581 ggctataatc tgaatgctct agccattgtt tcagctgctc agctttaggg ggattggcct
     8641 taatatcaat gatatcaacc tcagaaacca gggtctttag ctcagcaagg gctttttgac
     8701 aggtactaca ctttgggtat tggtaaatgg taatcattag ctactcctta ttaacactaa
     8761 tttgctcgtg cctgagcaac caggccttct tttcaagtcc tccagcatag ccaatcaagc
     8821 gaccatcagc agccagtaca cgatgacagg gaataaaaat acttaaagga ttacgtccta
     8881 tggcaccacc aacagcctga gccgaacgac actgcaggcg cttggcaagc tcaccatagc
     8941 tcaaggtctc tccccatctt atcgtctgca attctcgcca gacagctcgc tgaaaatcag
     9001 taccctgtgg agataagcaa tcaagcatgg gatagggctt cctctcaaag taagcgtcaa
     9061 gccacaaaca ggctcttttt aacagggcat gctgctcctg ccagatgggc tgcactttaa
     9121 tcccagcctg aaaatacctt tgaccttcaa accaggctcc tatcaaagca acatcagtcg
     9181 caaccaagga tatttttcct aagggcgatt gatacacaca ctcgtacaat ggcaagatct
     9241 gacctcccca cataatagct tattcccttg actatttatt ataagaaaaa gcctagctaa
     9301 aggcaagaag gagccctctg acaccacaac aaacgcatga aaaaacaata gcggctcttt
     9361 caatgctgcc atacaatcgt tagtgtcaaa agtcgcttac tatacagctg ccccccttga
     9421 aaaacgaagc tggaaagaca caacatgcta aagctgtttc acgcgctggt gcctgattag
     9481 atgttcttct aattaaaggc caatgttctg attaaaaagt catttcatgc gctgatacct
     9541 actcaaataa aaacacatag cgtggggcta gaccaatccc tcacaagtca tcaatagttc
     9601 gtctatgagc tacactttat cacattggga taggcagaca tatttgccgg ctcagttgta
     9661 cttgcctgat agctaaccaa aagcccgata agctttttcc gatcctatat caatagctgt
     9721 agcggctatc ctcgctaatc tcctgataag cggctctttc atggcttttc ttaatttttt
     9781 gataggctaa gcgctcgcca tcaattggta ccttgccaca gtaaacaaag cctaactttt
     9841 caatgatatg ccgcatgacc tgattatgct catgagtatc tatccgaaaa tctggtccat
     9901 gctgcccctc aatgagccct tgcaaaaagg tctgagcaat tccctgacca gtcctatcac
     9961 tcagcaccgc cacacgatga aaggtcacat aacggtggtg attatgctgc cacctgccat
    10021 cataaatctt gtcgtaggcg tcctcttggc catcaataac agccgcataa gcaacaatct
    10081 gcccctcaag caaagccaca tagccctgcc cttgcaacac atcagcagca atatcctgat
    10141 aagcaggata cccatctgct ttctgccatt ggctggagcc tgattgggct aaggcagact
    10201 tagctgaatt gatcactgtc atgatctgac taagctcatt aggaaaagca agtctaatct
    10261 ccatcgttca cactcacaat ctattctgat ttgatgatgc tatgctaccg caaaaagcct
    10321 tacaccttgt cactctgcta gggacacctc atagcggtat gcctgcttct catctcagct
    10381 gagtatagca caatagtcat catttgacaa aaagcctctt caaggattgc cagcaatcat
    10441 gctataataa agtaaatcac aaaggagaac cattatgatt aaagaatttt gtgctgaaaa
    10501 cctaaccatg ctaaaccaat tgaccagcca gtcggtcaat cgtgttgagc tctgcgacaa
    10561 tcttgcagtc ggtggcacca caccctctta tggtgtcatc aaggaagcct gcgacctcct
    10621 acatgacaag cagattagtg tcgcaacaat gatccgccca agaggaggtg attttgtcta
    10681 taacgacctt gaattgcgtg ctatggaagc agatatctta aaggctatcg aagcaggaac
    10741 tgatgccttg gtcataggct tactcactaa ggacaaccag cttgacaccg atgctatcga
    10801 acagctccta ccagctacac aaggactccc tctggttttt cacatggcct ttgacctgat
    10861 tgctcgcgac caacaaatcg caagcctaga gcagctcatt gactatggct ttgtacgaat
    10921 cctgcttcat ggctcaagcg ataccagatc catctatgaa aacattgacc atatcaagca
    10981 gttagtcaag gctgctcagc accgaatcga aatcatgatt ggtggaggtg tcacagctga
    11041 taactgccaa gagctaagtc aactaacagg aacagctatt gtgcatggca caaaaatcat
    11101 ctaactatca gctcaaataa aggaaaagtc actccctaca aggaggtaaa taatagcagc
    11161 ccttctcgtt gaaggccata cctgagccct tagactaggc tcctagcaaa ctaatagtat
    11221 aggaccttcg ctgcctttac atcaaaaagg ctgccgtcca gaaaaagaga aagccacaca
    11281 ttgatagaaa accatagctg gctctactac tatcagtatc tatcatcagc ttctgagctg
    11341 cctaaaagtt tcggtgatca ttaacaagta cagactattt gtttctaaat tagatcataa
    11401 aacagacaat tataggaagc gacaagtgaa tcattattca ttttttattg attactatga
    11461 tactataagt aaggatagcg ctttcttttt gtctttgctt tgcctgacta ttaggctcta
    11521 gatttatttt ttaccatact aatataagaa tcggaataaa taatgacaac aaggtatttt
    11581 tataagctat tgctaacgat gttgacacta gcattaggag gattttccct atctgcttgc
    11641 cactccaaga ttagtaagcc ctatcaagtc gctatttttg acaaggatca tgttaggacc
    11701 tttatggaaa aagctgacag tctggtgcct gttgagacca tctctcgaac acagcacaag
    11761 ctatttgagc gagaaagctt taagcaggcc aagcaagggt attttgcaaa gacaagagaa
    11821 ggaaatgacc tcaaggttct gttaactcac attgatcaag caagcctaga agaaaaagtc
    11881 cttcatgctg atggcaatga cgcctacacc tctacaactg atggtgatta cttttacaca
    11941 acagctgtct ttgccgatcg tattgactgc tacaagtatg accgccactt gaaaaaacag
    12001 gctcacaagt ctattctaaa tcaagacacc attaatgcca gcaatcagtt tctggtgatt
    12061 gatgacgctc tgtacctgct tgtcagcgct gtagacatca agagtcagca gcccaaaact
    12121 gagctatgga aaatggacaa atcctttact atcactgatc ggatagatct ggacgaaagc
    12181 actgcctatc tgcgcatggt caacgtcgga cgaacccttt acattaccca ggctgctgat
    12241 ggcattttag aaactggaga acctagacct ggtaacaagg tgatgaccta tgacttagat
    12301 agcggtcaaa agtcctatct catgcttcat gtcaatagtc ctagagccat ttaccaccat
    12361 gccaaaacca atgagcttat catcgaaaat gatcagcatt ataatcctga ctttgcatgg
    12421 accatctacc agctagatac cggagaggag agaaccattc gctttgagga gctagccggt
    12481 caggagacaa gctctcccta ctttatgatg acctcaagca actactactt cctctttcca
    12541 aaaaggcttt accgatacga ttgtagtaac catcagatga cctgcatcaa cctagatcag
    12601 tacggagtga cgcacgccca tgccttgatc gctaagccca caccataaat cacaacaggc
    12661 ctaatcacca ctcattcatc tacaccccaa tgcttagaca aagcagtgta ctgaccccca
    12721 aaagttggac acgacatatt agtgaaagga tttagttctg tattgcacag ggctaagtcc
    12781 tttcactaat atgtcgtgtc caacttttgg gggtcagtac actttgggaa agtatgtatg
    12841 aatctccaga aaaaatacct tatcaactac ctctatatga caagtatgag ggaaataata
    12901 gtttatttag agataatgcc tcaccaaatt ttagggcgga tgtcaaagat attacagcta
    12961 ctttagtggc tgttttaagt aatggttatc caaccgggaa aagcagtttt tgtaaagact
    13021 actgtcccga tgaaatcagg gcaagacaat taacccaatt agctatttgg tattttacag
    13081 atggtatttc tgaagaaacg ttgaaatcaa attatagtct aaatgatctt gaatttcaag
    13141 gattaaagta tttaatacag gctggcaaaa ctgctgggac tagtaacaat cgaactttag
    13201 atatctatat atctaaagat agaaattcaa aatttcaaaa tcttttaggt tctaccttag
    13261 tagttaaaac tccagaaaac aaagagaact gtcaatgtac taaaatttat atagaagaaa
    13321 atggaaaaga tggttattat ctttacatct atgaggatac gaataaaaac gataaatatg
    13381 acaaaaacaa agataaacta ctacagaaaa aatacataaa aaatgggaaa gacggcaagc
    13441 ctggcctaaa tggtcaacgt gggcctcagg gcgaacctgg gaaacaagga ccacaaggtc
    13501 ctagaggtga taaaggggaa accggagaaa aaggacaaga tggtaaaccg ggcaaacaag
    13561 gtgatcgtgg tccggctgga cctcaggggc ctagaggtga caaaggggaa actggagaaa
    13621 aaggagaccc tggacgtaat ggtaaagacg gtaaaccagg tgaaaaaggg gatcctgggc
    13681 aacaaggcat tcctgggcct aagggtgatc ctggaaaaga tggagaaaaa ggtgaacgtg
    13741 gagagcaagg acctcaaggc gaacgtgggg agcaaggacc tcgtggagaa aatcccactc
    13801 ctaccccaga tccaatgcca caaccaatgc ctgaccctgc acctaaacca gaatccaagc
    13861 cagaacctaa gccgatacct caaccagagg ttaagcctca gccagagaca aaacctcaac
    13921 aaccaaacaa gccatcaacc attactagcc aacctagcgg caaagcacta ccaaaaacaa
    13981 acgacacagg cagcttgata acagtattgg gaacaggctt gctctctctt cttggactgg
    14041 gcttcttaac tagacgcaaa agaaaacaat aattaaagca ctatctatag ctttttaatc
    14101 attggctatc aaacaaatca caaaaaagct tatcgtttta ctcctaacga taagcttttt
    14161 cgtattctct attacttggt cccaatacta tttttccagc tttaggctgg ttttgttaat
    14221 ccaaaataat atcagacaat tt
//
LOCUS       DARYLD010000052        14030 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYLD010000052 DARYLD010000000
VERSION     DARYLD010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14030
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..165
                     /locus_tag="TU651_001494"
     CDS             <1..165
                     /locus_tag="TU651_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897475.1"
                     /translation="VTYDSLVGQTRRHFDDKVAQARGLATKFKTVKEQLEEGIERTIA
                     TDQKLGGDFS"
     gene            162..554
                     /locus_tag="TU651_001495"
     CDS             162..554
                     /locus_tag="TU651_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897476.1"
                     /translation="MTALEKIRAAIRQKEEELEELQEHYHQERLQMAAAHDELRGNYN
                     QLQELYASTYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            573..857
                     /locus_tag="TU651_001496"
     CDS             573..857
                     /locus_tag="TU651_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897477.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGCLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRGQGRTALEQAIKTQNRGYSSLM"
     gene            complement(1056..1304)
                     /locus_tag="TU651_001497"
     CDS             complement(1056..1304)
                     /locus_tag="TU651_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL0897478.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(1358..2278)
                     /locus_tag="TU651_001498"
     CDS             complement(1358..2278)
                     /locus_tag="TU651_001498"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL0897479.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            2512..3141
                     /locus_tag="TU651_001499"
     CDS             2512..3141
                     /locus_tag="TU651_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0897480.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            3240..4517
                     /locus_tag="TU651_001500"
     CDS             3240..4517
                     /locus_tag="TU651_001500"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL0897481.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            4531..5193
                     /gene="deoC"
                     /locus_tag="TU651_001501"
     CDS             4531..5193
                     /gene="deoC"
                     /locus_tag="TU651_001501"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL0897482.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            5180..5569
                     /locus_tag="TU651_001502"
     CDS             5180..5569
                     /locus_tag="TU651_001502"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL0897483.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            5660..6712
                     /locus_tag="TU651_001503"
     CDS             5660..6712
                     /locus_tag="TU651_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL0897484.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6839..8371
                     /locus_tag="TU651_001504"
     CDS             6839..8371
                     /locus_tag="TU651_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897485.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            8364..9428
                     /locus_tag="TU651_001505"
     CDS             8364..9428
                     /locus_tag="TU651_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897486.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            9430..10386
                     /locus_tag="TU651_001506"
     CDS             9430..10386
                     /locus_tag="TU651_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897487.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(10424..11680)
                     /locus_tag="TU651_001507"
     CDS             complement(10424..11680)
                     /locus_tag="TU651_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL0897488.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(12200..13915)
                     /locus_tag="TU651_001508"
     CDS             complement(12200..13915)
                     /locus_tag="TU651_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL0897489.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         4038 a         2516 c         3281 g         4195 t
ORIGIN      
        1 gtgacctatg acagccttgt cggtcagacc aggaggcact ttgatgacaa ggtcgctcag
       61 gccagaggac tggccactaa gttcaagacc gtaaaggagc agctagagga ggggatcgaa
      121 aggacaatcg ctactgacca aaagctagga ggcgactttt catgacagca ttagagaaga
      181 tcagagctgc tatccgtcaa aaggaagagg agctagagga gctgcaggag cactatcatc
      241 aagagcggct ccaaatggca gcagcccatg acgagttaag aggcaactat aaccagctgc
      301 aagagctcta tgcctctacc tatcaggccg ttagcagcta cctcagacat tatgatgcta
      361 gcctgataac agaccaatat accgttctaa cgaggctgat tgatgactat cagcaccgaa
      421 cagagcagtg ctatcacgag caaggtcgca agatgtcgca gcaggaggaa gcaattgacc
      481 atcactatcg cagccagcga caggctatag agaaggacat cacagcgctg aggcgtcagt
      541 ggcgtgaagg ttaaggaaaa ggagataaga agatgattgc tatagagatg atcttaaccg
      601 gacaagagcc gatcaggact ttaaagaaag agctggatag gagattagtt cagtccatat
      661 gtgccccctt gaccttaggt tgccttcatg cccttcaaag gcgctatgac agtgaggtat
      721 ctcggattgc cacagacacc gcagatcata ttcagaccat tgtcaatcag ctagatagca
      781 gcattagagg gcaaggcagg acagcactag agcaagcgat caagacgcag aacaggggct
      841 atagcagcct gatgtgagac aggaaggact tactgtccta ccagctacag tcactacact
      901 gctagagctt gcggtgtgag cagcagtaag aggcaaaggc gttaccccag agggattgat
      961 ggatcaccat cactagtttg gagccattag ctgtgccaaa ggttttctaa agccaaaaag
     1021 aaaaaactcc gattggagtt ttcattggtt atgtattagc taagctttgc agcaagacgt
     1081 gctttatcgc ggcttgcttt atttttatga atcaaacctt ttgattgggc tttatcaatg
     1141 cttgaagaag cagcgcggaa aagctcttca gatgggttag cttcaaatgc cttgatagca
     1201 gtacgcatag ctgatttttg tgctgaattt ttttcgtttg ctttaacgtt aagctcagcg
     1261 cgtttaatag ctgatttaat atttgccaat gttttcacct ccaaattaat ctaactacac
     1321 cattatatag aaaatatagg tgtttggcaa gcacttatca ctttttgaga taaatttcat
     1381 caattttatg gtctgcagct ttatgaagaa tgagctcagc tcgattgcgt gtaggctcaa
     1441 taaacttttc cagattttct aggttaattg ttttccagac tttttttgca aaggcaatgg
     1501 cttcattttg tggcaatgag gtatatctag tgtaatagtt agccggatca tgcttagcca
     1561 gctctaaaag gcttaagaac cgttccaaat accattgctc aatatgatgg ctatctgcgt
     1621 caatataaat tgaaaaatca aaataatcac tcatatacaa tcgattattc tgttgatttt
     1681 gaaaaacatt aatcccttcg atgatgagga agtcaggatt ggtaaaggtt tgctgctgat
     1741 caggaacgat atcataaatc tcatgcgagt aaacaggggc tgatgcggtt tgtcctccct
     1801 tgacagtatc cagaaagttt aacaatagct ccatattata ggattctggg aagccctttc
     1861 gattcagcat attgtttttg atcagtgtgc tattagggta caaaaaacca tctgttgtga
     1921 ccaactcaac agtgctggtc ttgtgtgtgc gcgccaaaag aagctgcaat aacctgctag
     1981 ttgtggactt accgacggca actgagccag aaatcccaat aataaagggt ctttgctgaa
     2041 tatctttttt tagaaagagg cttttagaaa aagacaggtt ttcttgagcg attttataga
     2101 cttgaatgag atgaatcaag ggaaggtaaa cctcaacaac gtcgttgata tcaatattat
     2161 cattcaaact ggtgatgcta gtaagctcct cttgagtcaa taagggcttg cttttttgat
     2221 gtaattgctt ccaggatttt ctggaaattt tttcaaaagt aataaattcg tttgacatag
     2281 ttactcctac taattggcag tgcttacatt ataacatgtc aataaaaaaa ttgaaaaatg
     2341 tttcgtctga aattcttaaa aaaacactga aaaaccctat aaaaatcgaa caattttagc
     2401 ctaacaattg gctaatataa agttaatcgg tcaatgttcg gaatatatgg ttcgataaac
     2461 gaaaaaccaa gaaaaacaaa cgtcttgtaa accatttcaa agtgtgatag aatgaaaaag
     2521 catcgaaaaa agataggaaa acacatgaca aaaatgtatt atgatgaaaa tccagatagt
     2581 gctcatgata tccatcaatt gacggtcaat ttgttaggac agtcctttac ttttttgaca
     2641 gattctggtg ttttctcaaa aagaatggtt gattttggaa gtcaggtcct gctcaacaca
     2701 ttagattttc aagaaggtga tcgtctgctt gacttgggct gcggctatgg gccgctagga
     2761 cttagcttgg caaaggctca aggtgttgag gcgactctag tagatattaa tcatcgcgct
     2821 gttggcttag ctaagcagaa tgctgagagt aatcaggttg aggcgaccat ttttcaatca
     2881 aacctctatg acggtgtgac agggacattt gagcacatca ttagtaaccc acctattagg
     2941 gcagggaaaa aagtggttca tgagattatt gaaaagagta ttgatttttt aactaaaggc
     3001 ggtgatttga cagtcgttat ccaaaagaag cagggagcac caagtgctaa agacaaaatg
     3061 gaggccgttt ttgggaatgt gactattctc aaaagagaaa agggttacta cattttaaga
     3121 agtattaagg aaaggaattg agctcaagtg taaaaagtgg tattaaaaag catagcggta
     3181 ttttagtaag agttgccttc taatatcact attttctcag agcttttggt atcttgttga
     3241 tgagagcagt tgatttaatc caaaaaaagc gtgatggtaa agagctatct accgaagaga
     3301 tccagtggct gattaatggt tatgccaatg gtactgtgcc agattatcaa atgtcggctt
     3361 ttgcaatggc gatctatttc aagggaatgt ctacacgaga aactcgcgat ttgaccatga
     3421 gtatggttga gacaggtgag cagattgatt tgtcagctat agctggtatc aagacggaca
     3481 agcactcaac aggtggtgtt ggtgataagg tgacactcat cttagctcct ctagttgcta
     3541 gctttggcgt tcctgtagcg aaaatgagtg gacgcggctt aggccacacc ggtggaacgc
     3601 ttgataagct agaatctatc aagggctttc agattggtcg gacccaagag gaatttatca
     3661 agcaggtaca agagatcgga ctttcagtta ttggacaatc agataagctt gtgaaggcag
     3721 ataagctgct ttatgctctt cgtgatgtga cggcaaccgt tgatattgtt cctttgattg
     3781 caagctctgt tatgagtaag aaaattgctg ctggcgctga tagtattttg ctagatgtta
     3841 ccgttggtga cggtgccttt atgaagacta ttgaagatgc tgagaagctg tctagactga
     3901 tggttgacct tggtaaggag gttgggcgtc agacagtggc tgtcattaca gatatgagtc
     3961 agcctcttgg tcgtgctatc ggtaatcgct tagaggtgct agaggcaatt gatatcatga
     4021 aaggcaaggg acgcaaggat attactcact ttatttgtga gctagctcag attatgctgg
     4081 agcttgctgg tgctcaacac tctcttgagg atattcacca tcatttggtt ggcggagcag
     4141 ccttaaaaaa attagaagag atggttgttt atcaaggagg tgatcttgag gacctttatc
     4201 gtccatcaca ggcggctgtt caaacagagg tttttgcgtc agaagatggt tacatcacag
     4261 cattgcctgc tcttgagttt ggattgtttg caatgaggct gggtgctggt agagcagtca
     4321 aaacagatag tctggattat gaaacaggga ttgtctttga caagaaggtt ggtgacgctg
     4381 tcgctaaggg agagcgcatt gcagttgtct tttcacagga agccctagac gaaaaaatgc
     4441 ttacagaatt tgaaaaaaat gttaaaatag gggcggaaca cctagaggct aacgaaatta
     4501 tcaaaatcat ttcctaagga ggagtataac atgaatatta acaagtatat tgaccacaca
     4561 ctactaaaag ctgacagcgt tcaatcgcag cttgaccaat taattgagga ggctaaagcc
     4621 tatgactttg ctagcgtttg cgtcaaccct tgctgggtag cctatgctgc aaaggcttta
     4681 aagggaacag atgttaaggt ttgtacagtt gttggttttc ctttaggtgc aactacctca
     4741 gcaacaaagg cctttgaaac aaaggacgct attgaaaatg gtgctgatga gattgatatg
     4801 gttatcaata ttggtctgtt aaagcagggt gactaccaag ctgttgaaga tgatatgcgt
     4861 gcagtggtag aggctagcgg agacaaatta gtcaaggtga ttatcgaggc ttgcctcttg
     4921 actgatgatg aaaaggttaa ggcttgtcag ttggcggtaa atgcaggtgt tgactttgtg
     4981 aagacctcta ctggtttttc aactggcggt gcaaccgttt ctgatgtcaa gctaatgcgt
     5041 caaacagttg gtccagacat tggcgtaaag gcagctggtg gtgctcgttc tctagaggac
     5101 gctttagctt ttgtcgaagc aggagctaca cgtattggaa cttctgcagg ggtaactatt
     5161 atgaaaggtg aagttgccaa tggaggctac tgatttagtt tcgttagcca ttgaagctag
     5221 taaaagggct tatgtgcctt actcacattt cccgatcgga gctgctttaa agacaaagga
     5281 cggaacaatc tatactggca ataatatcga gaatgccagc tttggcttga ccaattgtgg
     5341 ggagcgaaca gctattttta aggctgtttc tgagggacat cagcagcttt tagaaattgc
     5401 catttatgga gagactgatg agccaatctc tccttgtgga gcctgtcgtc aggtcatggc
     5461 agaatttttt gaagccactg ctccagtaac gctaattgct aaggacggtc gtaccatgcg
     5521 cacaactgtt ggcgagttac ttccttattc gtttacagat ttatcgtaat ctggcttaat
     5581 tttgttatct agccattagg ctttatattt actttcggca attggtttgc tagaaatatt
     5641 tttaggaggg ttcatattca tgaacaagaa atttattggt gttggtttag cttctgtagc
     5701 tttattaggt ttagttggtt gtggtaatcg taacgcttca aagggatctg gtgatgctaa
     5761 aacagatttg aaggtagcag tggttactga cactggtggt gttgatgata agtcatttaa
     5821 ccaatcagct tgggaaggct tgcaggcttg gggtaaggac aatggactaa caaagggttc
     5881 aggctttgat tacttccaat ctacaaacga gtctgaatat gcaactaaca ttgatacagc
     5941 agtttctagt ggttatgagg ttgtttatgg tatcggattt gccttgaagg atgcaatcag
     6001 taaggctgct gatgacaaca acaaagtaca atttgttatc attgatgatg ttatcgaagg
     6061 caaagacaat gttgctagcg taacatttgc tgataacgaa gctgcttacc ttgcaggtat
     6121 tgcggcagct atgactacaa aaacaaaaac agttggtttt gtaggtggta tggaaggaac
     6181 agttgttaca cgctttgaaa aaggctttga ggcaggcgtt aagtctgttg atgactcaat
     6241 caagatcaag gtggactacg ctggatcatt tggagatgcc gctaagggta agacaattgc
     6301 agcagcgcaa tacgcagcag gtgctgatgt tatctatcag gtagctggtg gaacaggtgc
     6361 gggtgtcttc aacgaagcaa gaacaattaa cgaaaaacgt gacgaagctg ataaggtttg
     6421 ggtaattggt gttgaccgcg accaaaacga agaaggtaaa tatacatcta aggatggcaa
     6481 atcatctaac tttgtacttg catctactat aaaaggtgtt ggtaaggctg ttcaattgat
     6541 caataagcag gcagcagata agaaattccc tgcaggtaaa acaactgttt atggtctgaa
     6601 ggacggtggt gttgagattg ccacaacaaa tctttctaaa gacgttatca aagccatcga
     6661 agaagcgaaa gaaaaaatta aatctggtga cgtaaaagtt cctgaaaagt agttactgga
     6721 aaagagcgac cttcgtcggt cgcccttttt agagtggaac accttttgct tcagtaaagg
     6781 ttgtgacaaa tggctggctt tactgaaaca aaagattaaa ttgaaaggaa ataatcctat
     6841 ggcacagcat gtcattgaaa tgaaagagat tacaaaaaaa tttggtgatt ttgttgcgaa
     6901 tgaccatatt aatttgaatg tcagaaaagg cgaaattcat gcattgttag gagagaatgg
     6961 tgcaggtaaa tcaacgttaa tgaatatgtt agctgggctt ttagagccaa ctagtggaaa
     7021 cattgtcatt aacggtcagc ctgttgttat tgactctcct tccaaatctg ctagattggg
     7081 tattggaatg gtacaccagc actttatgct agtagaagct tttacagttg ctgagaatat
     7141 cattttagga aatgaagttg tcaaaaacgg ttgtcttgat ttaaaaaagg ccagcaagga
     7201 cattaaagag ctttctgaga aatatggttt agctgttgat cctactgcca agattgctga
     7261 tatttctgta ggggcacagc agcgtgttga aatcttaaag accttatatc gtggtgcaga
     7321 tattcttatt tttgatgagc caacagctgt tttaacgcct gctgaaatac aagagctcat
     7381 ggaaatcatg cgtaaccttg ttaaggaagg caaatccatt attttgatta ctcataagct
     7441 ggacgaaatt agagcagttg ctgatagagt cactgttatt cgacgtggga aaagtattca
     7501 aacagtagat gtagcaggtg caacctctca ggacttggct gaaatgatgg ttgggcgttc
     7561 agtttccttt acaacagcta aaaaggcagc agagccaaaa ggggtggtgc tgtcgatcaa
     7621 gaatttagag gtcgatgaaa atcgtggaat cccagcagta aaggggcttt ctcttgacgt
     7681 tagagctggt gaaattgtgg ggattgcagg gattgatggt aatggtcagt cagggctgat
     7741 tcaggccatt acaggcttga gaaagactag atctggtagc attacaatca aaggtcagga
     7801 ggttgttcat ttaagctccc gtaaaatcac agagctatca gtggggcatg tgcctgagga
     7861 ccgtcataga gatggcttag tgctggacct ttccttggct gaaaatactg cccttcagac
     7921 ctattataaa gagccactaa gtaagaacgg tattttaaat tacaatacaa tcaatgatta
     7981 tgctcgtaga ctgatgaagg aatttgacgt tcgtggtgcc aatgaattgg ttccagctcg
     8041 tggattttct ggcggtaacc aacaaaaggc tatcattgca cgtgaggttg accgtaaccc
     8101 tgatttattg attgtcagtc agccaactcg cggcttggac gttggtgcta ttgagtacat
     8161 tcataagcgt ttgattgaag agcgtgacaa aggcaaggcc atcctcgttg ttagctttga
     8221 gcttgacgaa atcttgaatt tatctgaccg tattgcagtt attcatgacg gtaaaattca
     8281 aggcattgtg ttgcctcaag ataccaataa gcaagaattg ggaattttga tggctggtgg
     8341 ttccattgat aaggaggaga gtcatgtcta aaaatgcaca aaagattgct gtgccaatga
     8401 tttctatctt gttaggattc ttacttggcg ctattgtcat gtttatcttt ggctatgatc
     8461 caatttgggg ctatgagggc ctatttcagg tagcctttgg tagtatcaaa aatattggtg
     8521 aaatcttcag agcgatggga ccactaatcc tgattgcact tggttttacc gttgctagcc
     8581 gtgccggctt ctttaatgtc gggctgtcag gtcaagcttt ggctggttgg attgctgcgg
     8641 gctggtttgc tcttgtcaat cctaatatgc ctcgtccgct tttaattctg atgactgtct
     8701 tgattggtat ggttgccggc ggaattgctg gcgctattcc aggtattttg cgagcttatc
     8761 ttggtacaag tgaagttatt gttaccatta tgatgaatta tattattctg tatgtcggta
     8821 acgctatcat tcaaagaggc taccctgaaa gtgttaagca aagtattgat tcaaccatac
     8881 aggtcagtga taatgccagc tatcaaagtc aatggctgtc agatttaacc aataattctc
     8941 gtattaatat cggtatcttt tttgcgctta ttgcaattgc agttatttgg ttcttactaa
     9001 acaaaacaac cctcggattt gaaattcgtt cagtaggtct taatccacat gcttcagaat
     9061 atgcaggtat gtccttaaag cgtacgatta tcctatcaat gatcatttca ggtgctttag
     9121 caggcttggg aggagttgtt gaaggcttgg gaacctttga gaatgttttt gtacagggaa
     9181 gctctctagc aattggtttt gacggtatgg ctgttagctt gcttgctgcc aattcaccga
     9241 ttggtatctt cttctcatca ttcctatttg gggtgttgag cataggtgct cctggtatga
     9301 atatcgcagg aattccacca gaattggtaa aagtagtgac tgcctcaatt atcttctttg
     9361 taggtgctca ctaccttatc gaacgctata ttatcaggcc taaaaaacta gtaaagggag
     9421 gtaaataaga tgagtttagt tactattttt gctttattgg tttcatcaat gcttatctat
     9481 gctacacctc ttatttttac aagtattggt ggtaccttct cagaacgagc tggtgttgtc
     9541 aatgtcggcc ttgaaggcat tatggtcatg ggggggggtt caggcattgt ctttaatctt
     9601 gaatttgctc atatctttgg taaagctact ccctggcttg cagttttggt gggaggagtt
     9661 gttggattga tcttttcatt gatccatgcg cttgcaacga ttaactttag ggcagatcac
     9721 attgtcagtg gtacagtgct aaatctgctg gcaccatcgc ttgccatttt cttagttaag
     9781 gtgatgtacg gtaaggggca aactgataat atccagcaat cattcggtaa gtttgatttt
     9841 ccgattctct caaaaattcc agttcttgga gatatattct ttagaaatac tagcttagtt
     9901 gggtatttag ctgttgcctt ttctttccta gcttggtttg tgctttacaa aacaagattt
     9961 gggttgcgtt tgcgctctgt aggtgaacac cctcaagcag ctgatacact tggtattaac
    10021 gtttacctca tgaaatatta tggggttatg atctctggtt ttcttggggg tattggtgga
    10081 gctgtctatg cacaatccat ctctgttaac ttcgcagtga caaccatttt aggacctgga
    10141 tttattgccc ttgccgctat gatttttggt aagtggaatc cggtaggtgc tatgctatct
    10201 agcttgttct ttggattatc acaaagctta gcagttattg gggcacaatt accagtattg
    10261 gaaaaaatcc caacggttta ccttcaaatt gcgccatacc tattgaccat catcattttg
    10321 gctgctttct ttggacaagc agtggctcca aaggcagacg gtgttaatta catcaaatca
    10381 aaataaaaaa agctcaatgt caactgtagt gggtgactga tagctaagca cgagagaaga
    10441 cgaatgtcgt cttctctttt gtgatattca aagcgaggta gatacgtttt ttaaagttgt
    10501 caaagttccg aaatccgaaa gcattgcgct tgatatcttt gataagtttg ttagtggctt
    10561 ctaacttagc gttagaataa ggcagttgaa tggcattggt gatgtaatct tggtagcgac
    10621 taaaggtatt tagagctgtt ttaaaagtct gattaagatg tggtagtgtg tcatgaatta
    10681 aaccaaagaa atgcttggca ttcttttctt gcaggtgaaa aaggagcagc tggtacaggt
    10741 cataataaga gtttaactca ggcactagtg agaagatctt attgagacat tctctaggag
    10801 ttaaggtttg tctgaaggtg cgggaataga aaggcttaag agaccgtttt ctgctatcct
    10861 tttgaataag cttccagtag tacttaagag ctctatattt aagagacttc ttgtcaaatg
    10921 gtttcatgat gtcactacgt atttgcttga gagctctatt gatgtgctgg acaatgtgaa
    10981 aacgatcgag aacgatttta gccttaggaa atagaatttt aatgagagga atataacttc
    11041 cagacatatc gacagtgacg actttcacct tgtttctagc ctctttagag tacttaaaga
    11101 aatgatttcg gatggttgtt tgacgtctat tatcaagaat ggtaatgatt ttcttagtgt
    11161 taaaatcctg agcaatgaag gctaatttac ctttctgata agagaactca tcccaagaga
    11221 gaacttctgg caaattggcg taatcctctc ggaaatgata ctgcttaagc ttgcgataga
    11281 cggtagaagt ggagatagcg agcttagaag cgatatgggt gagagccttt ctgttgagta
    11341 aaagctgagc gattttctgt ctcactatct cagaaatttg gcaatttttc ttaaccaggg
    11401 tagtttcaga tacagtgact tttcgacagg atttgcattg aaaccttctt tttttcaaac
    11461 gaatgagact aggaaagcct ccaatttcga taaagggaat tttagagggc ttctggaagt
    11521 cgtatttgat ttgttttccc gcacacagtt tacatttagg agggttatag tctagtgtag
    11581 cgatgacttc aatatgagta tcatgctgga tagctttagt caaggtgata tgtttgtctt
    11641 tgattccaat gagttgtgtg gtattattga ggtgttccat aagatacctt ctaaatgata
    11701 gtttagtcgc ttttcatgat aagtcttatg ggactttttt gatactcaaa aagccctata
    11761 atctccacag tagccttacc cactacagaa attatagagc catcttagaa cactggactt
    11821 gttcgctttt taatgaatta aatttagtag atcctttaaa ggcatgctat caagcttttt
    11881 atccttgact tttgtttagc aagtgaagtg ttcacaaaag ctagctaaaa cactgagctg
    11941 acaatgtaga gaatggctcg ttttgacaag gttagagtgc tttttgctgt atggttttta
    12001 atccacgcac ctgaaaaaga aaggacagga cctgtgcgag cttacttgtg gttagtaggt
    12061 ttcaattcat gctcccaaaa aggaagcaac gcaactctga gaaaggtctt agaccacttt
    12121 cccagtttgc ctcacagcta atggtgtaaa acaaatagac caccctgtaa caggtggtca
    12181 tggttagata tcagctcatt taagagacaa aggcgttgat ttcagattca atattggcaa
    12241 ttttttcttc ggcaagcgca agggtgtcac caacagttgc gatataaaat ttaatttttg
    12301 gctctgttcc tgatggtctt acagcaaacc atgaatcatc agctagggta tattttaaga
    12361 cattgcttgg aggagtggtt agctgggttt gaccagcttt atgagttgcc gtctgactga
    12421 ggaaatcctc tgttaacaca atatcagtgt gattaaactg cgcaggggca tgcttgcgga
    12481 atttatccat aatctgtttg atttcagctg cgccatcaac accagacagt gtaacagaaa
    12541 tggttttttc tgcaaagtag ccgtattctt tgtaaatgtc atcaatacca tcagcaaggg
    12601 ttagtccacg agagcggtag taggcagcaa tctcagccac caatagcacc gcttgaatag
    12661 cgtccttatc acgtacaaat ggtttaatga gataaccaaa gctctcctca aagccaaaca
    12721 tataggtgta attgtgcttt tcttcaaatt cttgaatttt ttcagcaatg aacttgaagc
    12781 ctgttaagac attaaacatg gttgccccgt agctctctgc aattttagtc actaattcag
    12841 tagagacaat ggatttggca agagcggcat tgttaggtag ggttccagcc tgctgatgtg
    12901 cttctaaaat atacttagca attaaagcac caatttggtt gcctgatagg ttgcgatagc
    12961 tgccatctgc ctgccgaatt tcaaccccaa gacggtcagc atctggatca gtagcaacaa
    13021 gaacatcagc atcaacctga cgtccaagct cctcagcaag agtaaatgcc tcttgacttt
    13081 caggattagg agatttgacg gtagaaaaat ctggatctgg cttagcctgc acctcaacca
    13141 cctgaacgga cttaaagcct gcttgtgcca aggcacgacg tgctagcatt tcacctgttc
    13201 catgaagagg tgtatagaca attttcatgt cacgaccata gtcattgatg aggtcttggt
    13261 tgatattgac ctttttgacc tcttctaaat aagcaaggtc aacagcttca ccaataacct
    13321 cgatgagccc attagctttg gctttctcta aatcagcaag cctaatggca aaggggttat
    13381 caatcgcacg aatgtaatct gttagagcgt cggcgtcagc tggaggcatt tgaccgccgt
    13441 cagacccata aaccttatag ccgttgaatg gtgcagggtt gtgactggca gtaaccatga
    13501 taccggcaaa agcacccaaa tgtcgcacag caaaggaaag ctcaggtgtt ggccgaaggc
    13561 tttcaaaaac gtatgattta atgccatgag ctgctagtac ctgtgcagat tcaaaggcaa
    13621 attctggaga aaaatgacga gaatcatagg cgatagcgac accggccttc ttagcagctt
    13681 ctccctttga ctcaactaat gctgccaagc cctcagttgc ttggcgaaca acaaaaatat
    13741 tgatacgatt cgttccagcg ccaatatagc cacgcatacc agctgttcca aattcaagat
    13801 tggtgtagaa ggcatcttcc tttgtttttt cgtccatgct aagtaattca tctcttaaat
    13861 aggctggtag atctggaata tcaagccatt tttgatagtt ttctgtgtaa gtcatagtat
    13921 tctcctttat atttttaacc gctttcatta tatcatgttg aaaaggaaaa atcacttatt
    13981 ttctgtaata gcttccaatc attttttcac ataaggatca atttccttgc
//
LOCUS       DARYLD010000053        13179 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYLD010000053 DARYLD010000000
VERSION     DARYLD010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13179
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            304..1848
                     /locus_tag="TU651_001509"
     CDS             304..1848
                     /locus_tag="TU651_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0897490.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            1932..2960
                     /locus_tag="TU651_001510"
     CDS             1932..2960
                     /locus_tag="TU651_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0897491.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            2981..4771
                     /gene="uidA"
                     /locus_tag="TU651_001511"
     CDS             2981..4771
                     /gene="uidA"
                     /locus_tag="TU651_001511"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL0897492.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            4813..5484
                     /locus_tag="TU651_001512"
     CDS             4813..5484
                     /locus_tag="TU651_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL0897493.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            5667..6284
                     /gene="eda"
                     /locus_tag="TU651_001513"
     CDS             5667..6284
                     /gene="eda"
                     /locus_tag="TU651_001513"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0897494.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            6312..7709
                     /gene="uxaC"
                     /locus_tag="TU651_001514"
     CDS             6312..7709
                     /gene="uxaC"
                     /locus_tag="TU651_001514"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL0897495.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            7971..9065
                     /locus_tag="TU651_001515"
     CDS             7971..9065
                     /locus_tag="TU651_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL0897496.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            9081..9920
                     /locus_tag="TU651_001516"
     CDS             9081..9920
                     /locus_tag="TU651_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL0897497.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            10184..10987
                     /locus_tag="TU651_001517"
     CDS             10184..10987
                     /locus_tag="TU651_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0897498.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            11102..12892
                     /locus_tag="TU651_001518"
     CDS             11102..12892
                     /locus_tag="TU651_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL0897499.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
BASE COUNT         3593 a         2449 c         3235 g         3902 t
ORIGIN      
        1 gttggtgggg tgacgatact gacctcaaag gggttggata agtattggta aaaggcttga
       61 gctctgtctt gtgcagggct cagttttttt gatgtcaatg agtaattgtc tgatgattat
      121 ttttaaagac accagaaatt atcagatgaa tttaatgatt aaaatcctaa ataagcttta
      181 ttttttaaaa ttaggcgaaa aaagtttaaa ttgtgttgac aaatcatcag atgaatagta
      241 agataagcat gtagaaataa aacgcttaca caataagcga atgataaaag ggggatttct
      301 ctgatggaga aaacaattga ccaaagggtt gaagaggtta cctataaccg cgctaaggtt
      361 tggcagcttg ttttatttgc tttaaacaat gcttcaacca atatctacct attcacattt
      421 atgtttgtga cctacttttc aacaggtgtt ctaggcttgg cagctatttt tgtcagccag
      481 atcatgggtt atattcgtat ttttgatggc tttattgatc ctgcgattgg tatcttgatt
      541 gataaaacag aaactaagtt tggtaagtat cgtccgatcc taatcatcgg aaatattatc
      601 acagccctat cacttattct gctgcttggt ctaagtggag ttagtgagaa cattcgtttt
      661 ccacttttta ttctggtttt gattatccat aagatcggct actctatgca gcaaaccatc
      721 actaaggctg gtcagacagc ccttactaat gatccgaagc agcgtccaat ctttaacatt
      781 gttgatgcca ttatgacaac cttgctgatg actggtggac agtttgttgt gtcaagcttc
      841 ttggttccaa aatttggtaa cttcacacca gccttcttcc acgtgttgat ttatggcacg
      901 attgttatct cagctatttt gggtctattg gcagtgcttg gtatttggag caaggacaga
      961 aaggaattct ttggtcttgg tgaaaatacg caaaagacag ctctgaagga ctatttgaag
     1021 gttatcaagg gcaaccagcc gctacaggtc ctatcaattg ccgcagcctt ggttaagttt
     1081 gctgttcaat tctttggtga ttcggttgtc atggttatct tgtttggtgt tttatttggt
     1141 aactatgctt tgtctggtca attctcattg ctgtttattg ttccggggat tttgattaat
     1201 attgcttttt caggtattgc tcgtaagaga ggtttgcgtt tctcatatat cagagctctt
     1261 cagattggct tggttggctt gttagccttt ggtattgtgc tctttatggg taataaaggg
     1321 gatctcagcc taagtcatat taacctttac actattttgt ttactgtgac actgattatt
     1381 gctcgctatg cctcacaagc gcctgctagc ttggtgctaa caatgggagc tgatatttca
     1441 gactacgaaa catcagaatc aggccgttat gtctcaggaa tgattggtac aatcttctcc
     1501 ttgactgact cgattgcatc atcatttgcg ccaatggtta ttggtgcagt gctggctggt
     1561 attggttttt caaagactta cccaacgatt gagacaccgc ttaccccaag tctaaagatg
     1621 gccttgattg cgctgcatgt cggtattcca tttgtagcct tactagtggc tttgattttg
     1681 atgtcattct acaagcttga caaagaggaa atggtgcgta ttcaagagaa gattcaagtg
     1741 atgaaagcaa gctctgataa ggaacgcgtg caggctatcg ctaaaaatgt accactgtca
     1801 gacatggact atgttgatgt gacaaaatat cctgttgata aggattaggt gctgggtcag
     1861 ctatttcttt gaggagtggc tgactttttt ataaaataat agagtagctt gatagtataa
     1921 ggaggaatgt tgtgaaaaaa gttgtatcct tgggtgaaat cctcttgcga ttgtcacccc
     1981 ctcaatacca gacgttaaag caggcaacaa gcctagattg tcaatttgga ggttctgagc
     2041 ttaatgtcat ctcaagcctt gctcagctag ggcatcaggt ctctcttatt tcagctattc
     2101 cagacaatga tctgggacaa atgacaaaaa cctttctctt ttcgcgtcaa attaatcagg
     2161 agcatattat cgaaaagggt cagcgtttag ggctttatta ttatcaaaag ggcttttctt
     2221 tgcgagcaag tcgggttacc tatgaccgct gtcattcagc cttttgggag tcaaagcgtg
     2281 ctgactatga tttggagcat gtttttgatg aggctgattg gtttcatgtg tctgggataa
     2341 cgcctgctct aacgagtgat ctttatgagc tgacctatta tttgatgaca aaggctaggg
     2401 cagagggatt gactatttcc tttgatttga attttagggc tagtctatgg tcctcctttc
     2461 aggaggctag agatctcttg tcgcctcttg ttcagctggc tgatgtttgt attggcattg
     2521 agccgctgac gcttaaggga agcggcgcgc ttgatttaaa ggatcaatta ggcttgaata
     2581 gaccctatga tgatgaagcc ttgttgaagg aggtgctggc taggttagct gatacctatg
     2641 gggtaaaatg ctttgccttt acccagagag agatggacta taccaatgaa tacctgttaa
     2701 aggcctacct gtatcaaaat ggcagccttt ataaaaccca aaaatctggt attcaggttc
     2761 tggaccgagt agggacgggc gatgctttta cggcagggct gattcatggc ttattaagtt
     2821 ataaagacga gcaggctact ttagatgttg caatggctag ctttaagttt aagcatacca
     2881 ttgagggtga tagtaatatc atgacacaag atgacattga tcatttactg gccaaggaat
     2941 cgcatgagat tcaacgataa tgtgataaag gagaaatcgt atgttatacc caatactgac
     3001 aaaaacaaga aagatttatg atttaggggg gctctggcaa tttaagctag gagaccataa
     3061 cccgcaggag ctcctagcct ctgatgagct gatggttgtg ccgacctcct ttaatgatgt
     3121 ggttgtggat aaggacaagc gcaattacat cggtgatttt tggtacgagc gctttgttga
     3181 tgtgccagat cttgctgctg atgaggagct ggtacttcgc tttggctctg tcacgcacaa
     3241 tgcaacagtc tatgttaatg ggcaagcttt agggcaacac aagggaggct tcactccatt
     3301 tgaggtgttg gtgcctgaga cccattatca ggataatcaa attaaggtat ctgtttgtgc
     3361 caataatatt ttagattata ccagccttcc agtgggcaat tatagtgaag aaactcaaga
     3421 ggatggcagt atcaaaaaaa ttgtcaagga gaattttgac ttcttcaact atgctggtat
     3481 tcaccgtcca gtgaagctta tggtgcggcc aaaatgccat atctcagata tcacgatcac
     3541 gagtgacttg tctgaggata tgacatcagc cttagtcgag gtatctgttg aaacctcagc
     3601 agctgttgat gaggttaagg tgacgatctt tgatgaagag cacaagctcg ttgcgcaggc
     3661 tattgatggc aaggcaagac ttgataaggt tcgtttatgg gaagttttag atgcttatct
     3721 atacactgcc cacgttgaga tcatcgtaga tggcaatgtt gtagatagtt atgatgagcc
     3781 atttggtatc agaagtattg cagttgaaaa aggacaattt ttactaaatg gcaagcctgt
     3841 ttatttcaag ggctttggta agcatgagga tacctttatc aacggtcgtg gattgaatga
     3901 agcagctaat ttaatggata tgaatctgct caaggagctt ggtgccaatt catttcgtac
     3961 ctcacactac ccttactctg aggagatgat gcgtctggca gatcgtatgg gaatcttggt
     4021 tattgatgag gttccggcag tagggctctt ccaaaacttt acagcctcct tggatctttc
     4081 gccaaaggac aatggcactt ggtctgtcat gaaaactaag gaagcgcatg agcaagcaat
     4141 tcgtgagctc gtcaagcgtg acaaaaatca cccttctgtt gtcatgtggg tcgtggccaa
     4201 tgagcctgcc agccatgaag agggagcaca cgaatacttt gagccgctga ttgctcttta
     4261 taaggcacta gatccgcagc agcgtccagt aacattggtt aatctgctat tagcaacacc
     4321 tgatcgagat aaggtgatgg atctggttga tgtgatctcc ttaaaccgtt attatgcttg
     4381 gtatgttgat catggagact tgatcaaagg agaggttggg ctgcgtcagg agctattaga
     4441 atggcagaag aagtttccta acaagcctat cctgatgaca gagtacggtg cagatacgct
     4501 tcctggtctt cattcgatgt gggatattcc atatacagag gaatttcagt gccgcttcta
     4561 tgagatgagt caccgcgttt ttgatgagat tcctaatcta gttggagagc aggtatggaa
     4621 ttttgctgat tttgaaacta atctgatgat cttccgtatt caaggcaatc ataaggggct
     4681 tttttctaga aatcgccagc ctaagcatgt tgttggtttg tttaaagagc gctggaatac
     4741 cattccccac tacaattata aaaagaaata gtgtacaata gtagctagca ataagtagga
     4801 agaagggatt gtatggctag gcctttagtc gaaaaaacag cagagcgctt gttaaagcta
     4861 attttagaac gtgggtatga ggttggagca aagctcccca atgaatatga gttagcacag
     4921 gacttagagg ttggaagaag cactattaga gaagctgtta gaagcttagc aactagaaat
     4981 gttttagagg ttagacaagg atcaggtact tatattagct cgaaaaaagg tgtttctgag
     5041 gatcctttag gcttttcctt agtcaaggac acagccaagc tgaccgctga tttgtttgaa
     5101 ttgcggctat tgcttgagcc taggattgcc gctttgacag cacagcatgc aacgccaaag
     5161 gaggttgaag ccttagagaa gcttgttgtt gatattgaag aggccgtagc tgctggtgat
     5221 cctaagcatt tgcagctgga tgtgaatttc cattccttga tggcaaaata cagtggcaat
     5281 attgctatgg atagcttgct accggtgatc aatcagtcga ttcatctgat caatgccaat
     5341 tacacaaatc gtcagatgaa agaagattct ctacaagccc acagagatat tctgaatgcg
     5401 attaaagcgg gagatccgat cgcggcacat gacgctatgc tcctgcacat catgacagtt
     5461 aagcgaacgg cttttctatc ataagcttaa gcttgcttgc cggaaacagt ctattgagtt
     5521 ttgagtgatt tgcttcttgg ctcgaataag agggcttggt tttagagata ctagaaccaa
     5581 gtcctttttt tgctttttcc ttgacaaatc atctgatgat ttatataata aaactaagac
     5641 aacggtttca tgaaaaggag gagcctatgc taaaccgatt aaaagagaat tatttttttg
     5701 ctattattcg tggaaaaaca gtagaagacg ctattgccat tgctaagcat gctattttag
     5761 gcggtattcg taatatcgag attacctatt ctactccaaa tgcttcagag gttattagaa
     5821 tattgtcagc tgagtttgag catgatgatg ctgtgattat tggagctggg acagtgatga
     5881 cgcctgatct ggcaagagaa gctattgcag caggtgctag ctttttagtt agtcctcatt
     5941 tttctagaga aatagcagag gttgccaatc aggcatcaaa tctttatttc ccaggctgtg
     6001 caacagctac tgaaattgtc acagcaatga atgcctcttg tccgattatt aaggtctttc
     6061 ctggaggtgt tgtaggacca ggctttatta aggatattca tggtcctatt cctgaggttg
     6121 atttgatgcc atcaggtggt gtgtcgattg acaatgtcaa ggagtggaaa aatgcaggtg
     6181 ctgttgctgt tgggattggt tcagccttag ctagccgagt tgaggctgag ggctatgata
     6241 gtgtaacccg tattgcagcg tcatttgtat cagcccttga ttaagggaat tggtcataag
     6301 aggaggacga gatggctttt aatgacgaca attttatgct aaaaaatgag gcagcaaagc
     6361 gcctctatca acaaatcaag gatcagccta tttttgatta ccattgtcac ttagatccaa
     6421 aggaaatttt tgaggacaag gtttatgaca atattgttga cctttggctt ggtggtgatc
     6481 attacaagtg gcgcttgatg cgcgctaatg gcatttcgga agaagaaatc acaggctcag
     6541 cctctaagct ggataaattc aaggcctttg cccgtacact tcagcgctcc tatggcaatc
     6601 ctgtttacca ctggtcagtg atggagttga aaaatgtctt tggtgtctgt gagctactga
     6661 ctgaggataa tgcagaggaa atctatcatc gtatcaatgc ttacttggtt gagcaccaga
     6721 ttagtcctag aaagttgatt gcagatagcc gagtgcggtt tattggtacg acagatcacc
     6781 cgcttgatga cctagcttgg cataagaggt tagctgctga tgataccttt gagacggttg
     6841 tcgcgccaac ctttagacca gatgaggctt ttattgagca tcagcgcttt gcagattttg
     6901 tggctcgtct tgctcaagct accggaagaa ctattacaga ttttaagagc tttatagcgg
     6961 ctatggaaga gcgtattgcc tattttgcag aaaatggttg taaggccagt gacatcagct
     7021 ttacagagat tgtctttgaa gcagcagagc cagagcaatt agaccgtctc atgacaaggg
     7081 ttttagaggg ctatcagccg cagccgttag aggtcaagca atggcagaca gcggtgtttg
     7141 cagagctttg caggctttat aagcactatg gctttgttac tcaggtgcat tttggtgctc
     7201 ttcgcaataa tcattcagct atattcaaca agctgggggc agatgtgggt gttgactcac
     7261 tgggagacca aacaggacta gcaatcaata tgaatcgcct gctggatcat ctggtgcaaa
     7321 gagacagcct gccaaagatg atttggtata acctaaatcc gagctataat atcgcggttg
     7381 ctaatacact agctaatttc caagccaatg aaaacggtat tgcgggctat ctgcaattcg
     7441 gtgcaggctg gtggtttgct gataccaagc ttggtatgat tagccagatg aatgccttgg
     7501 ctgagcaagg tttgttagct aattttgtcg gcatgctaac ggattcacgt tcatttttat
     7561 cctatcagcg tcatgattat ttcagacgta ttttgtcgac ctaccttggt gagtggattg
     7621 aagaaggtga ggtaccagag gattatcagg cacttggtaa aatggctcag gacattgcct
     7681 acaataatgc tatccagtat tttaactagg ctgccttggt cgttaactag aagaagcata
     7741 gaaatatgat gttgctctat gattaaggtc ctagtcttaa aagaggctag gacaatatcg
     7801 gcctgctagc tgctgtcggc gtcttgttga ttgactagat tacaaaggct agaccaagta
     7861 gcaggcccag gccctttagt tgcaagggta ttagccccaa aaacaataat aaataacaat
     7921 tgtgtgaatc gaaaggaaaa ggagtttacg agaactcgag gtatgatact atgaaaatgt
     7981 cgtttcgctg gtatggaaag catgatccag taagtttaga ggaaatcaag gccattcctg
     8041 gtatgcaggg aattgtaaca gctgtgtatg atgtaccagt tggtcaggct tggccactag
     8101 aaaatatcct tgaattgaag aggatagttg aggctgcagg ccttgagatt tcagtcatcg
     8161 aatcaattcc tgttcacgag gacatcaagc aaggaaagcc caatcgtgat gagctgattg
     8221 aaaattataa gacctctatc atcaatgttg gtaaggcagg tattcctgtg gtttgctata
     8281 attttatgcc agtgtttgat tggactcgct cagatcttaa ttacccattg cctgatggat
     8341 caacctcact tgctttttta aaggcagact tggcagatgt ggatcctgtg gcagatgatt
     8401 tgaacctacc gggttgggat ttttcttact caaaagaaga gatgaaggct attattgagc
     8461 attatcgtca tcatatttcc gaagaagacc tgtgggctaa tttagattat tttattaagg
     8521 ctattatgcc aacagcagag gcagctggcg ttaagatggc tatccaccct gatgatcctc
     8581 cttatggtat ttttggctta ccacgtatca taacaggtca aaaggctgta gagcgcttct
     8641 tagaccttta tgattcccct aataatggga ttaccatgtg tgtgggctcc tatgcttctg
     8701 atcctcaaaa tgatgtgatc gctatgacgg agtacgcgct taagcgccag cgtattaact
     8761 ttatgcatac gcgtaatgtc actgctggtg attggggctt ccaagaaacc gctcacttgt
     8821 cacaggctgg tgacattgat atgaatgcta ttatcaaatt attggttgat tatgactggc
     8881 aaggaccact tcgtccagat catggtcgtc gtatctgggg agatcaaacc aaaacccctg
     8941 gctatgggct gtatgaccgg gcacttggtg cgacctattt taatgggctt tatgaggcta
     9001 atatgcgtgc agctggaaag ataccagatt ttggcattac tgtaaaaaca gttggagata
     9061 aatagaaaaa ggggcatgag atgagtcgag ttattgaatt taaggacaag gttgttgtga
     9121 tcacaggagc tggcggtgtc ctttgtggca gtatggcaaa ggcatttgca aaagcagggg
     9181 ctaaggtggc actgttagac cttaaccaag aggcggcaca ggcctttgtt gatgatattg
     9241 aggcagaggg tggtattgca aaggcctatc aggcaaatgt attgtctaaa gaaaacctag
     9301 aggccgttcg tcaggcagtt ttagcagatt ttggtccagc agatatttta gtgaatggcg
     9361 ctggcggaaa cagccctaag gcaacaaccg ataatgagtt tcacgacaca agcctgccag
     9421 aggatacaaa aaccttcttt gaccttgatg aagcaggtat cagctttgtc tttaatttaa
     9481 actatttagg caccttgttg ccgacgcaag tctttgctca ggatatggtt ggtcgtaagg
     9541 gggcaaatat tattaacatt tcttcaatga atgcctttac gccattaaca aagatcccag
     9601 cctattctgg ggctaaggca gccatttcca actttaccca gtggttggct gttcattttt
     9661 ctaaggttgg cattcgttgt aatgccattg ctcctggatt tttggtaacc aatcaaaacc
     9721 gtagcctcct tttcacagag gacggacagc caacggctcg tgctgaaaaa atccttaaga
     9781 atacaccaat gggacgcttt ggtgaggcag aagaattaat tggaggcctc tttttcttgg
     9841 ctgatgagca gtctgcttcc tttgtgaacg gcgttgttct gccaattgat ggcggatttg
     9901 cagcttattc aggcgtctaa gctaaaaaat aaaccacttg agaactcaaa ctgcaatgcc
     9961 tcaagtggtt tttctatcgt gacagcttgc tttgtagcca agctgccatt aataaaggta
    10021 tgatgatttg tggcttctat tgttccttat cactctagcc ttttttagca atcaacaagt
    10081 aatgatagct tttaaaaatg aaacgctgct tgattaggat ttatgattga cagcgttttc
    10141 ttactgtgtt agaattaatt catcagatga tttggaggtt ggaatgacag ctaaaactga
    10201 acaatttgtc ttttgtgtgg actcagatgg ctgcgcaatg gacaccatga cttataagca
    10261 tcagctcttt tttggtccgc ttgcggcgga ttattttgcg gtagcagacc aagcgtcttt
    10321 cttaaaagag tgggatcgca ttaatcttta ttcgcgtaca cgcggtgtta accgctttgt
    10381 tgggcttgtt atggggctag aatacgcagg agttacaggg attgacgctt taaagcaatg
    10441 ggtacaacac actgcctcat tatccaatca gtctctggag gcggagcttc ttaagcgtcc
    10501 tagtgatgac ctgcaaaagg ccttggactg gtcaaatgag gtaaaccgtc agattgaggc
    10561 ctacaaagga gaggcattgg catttctagg agctttagct gctcttaagg ccttgcacca
    10621 gcttggccag gtttttgttg tcagctcagc taataaagag gccgttcaaa aggaatggca
    10681 ggatcaaggc ctgatgacac atgttgatgg cttgtattgt caggatcgtg gcaaaaaaga
    10741 ggctgtcata gcacagctca ttgatgaagg atatgtgaga gagcgcatga tgatgatagg
    10801 agattcacca ggtgatctag cagctgctga gcaaaaccag atcacttttt ttccaatcct
    10861 cgttggtaag gaggctagct cgtggcagga tctgtcacat gctgctgaag cttttacaac
    10921 tggtgacttg acagagcttg atgtcaagag ccttacagaa gccttctggc gtaatcttga
    10981 taggtaggca ggtagctgac cagtggagct gagcctgtta gggcttggta gcaggttgct
    11041 gtagcgccat tcattaaaac agaaaagcaa gcagagaagg ctttagttga aaggaagtac
    11101 aatgacacat ttagtagatt taagaaaaaa accatatagc ctagacgaag aagctatttg
    11161 ctgggtggag gataccattg cagcaatgac cttggaggag aagataggtc agctatttgt
    11221 taatatgggg gctagtcgat cagaggatta tttaactcag gtgcttgagg attatcatat
    11281 tgcagctgtt cgctacaata aaggcatggc ttcagaaatt tgggatcaaa attatatttt
    11341 acaaaccaaa tccaagattc caatgctcat tgctgccaat acagaggctg gtggtgatgg
    11401 tgctgtcaat gatggcacta aggttggtga tgaaatcaag gtagctgcga caaacgatcc
    11461 taaatacgct tatgaaatgg gacggattgc aggactggaa gcgtcagctg ttggctgtaa
    11521 tgcctccttt gcgccaattg ttgatttgac gcgtaattgg cgtaatccaa tcattgctaa
    11581 tcgcaactgg ggggtaaatg ttgatcaaat cattgagctt tccaaagagt atatgaaggg
    11641 gattatggaa tatggtatca tgccctttgc caagcacttc cctggtgatg gtattgatga
    11701 gcgtgaccat catttgtcct ttgcctcaaa cccaatgacc aaggaggagt ggctatctag
    11761 ctttggacgt atttatggcg agcttgcaga ggctggctta cctggtatta tggcaggaca
    11821 tattcacctg ccaaatgttg aaaaggccat gcaccctgag cgtgagctag atgatatgct
    11881 tccagcctca cttaataaaa ccctcttaga tgagctgctg cgtggtgagc ttggctataa
    11941 tggtgctatt gtgactgacg cttcgcatat ggttgcgatg acagcctcaa tgccacgtcg
    12001 cttattgtta ccaacagcga ttgaggcagg ctgcgatctc tttttattct ttaatgaccc
    12061 agatgaagac ctacaatgga tgaaagaggg ctatgaggca ggaattttaa gtgacgaacg
    12121 ccttcatgac gcccttcgtc gtacgcttgg cttgaaagca aagcttggac ttcatcgctt
    12181 tgaaggacac cgagaagata ttatgctgcc taaggacaag gcgatggtct tgattaacac
    12241 accagaggct caagcaattg cagatgaggt tgccgacaag gccattaccc ttgtgaaaaa
    12301 caagcaggca gggattttcc cggtaactcc agagcgctac aagcgtgtgc tgattgttaa
    12361 cgtggagggc tataagggtg gctttggtgc tatgattgca ggacagaaga aacgggcctc
    12421 agacattgtc aaggaattgc tagaggcgcg tgggcatgag gtaactgtct gggaatcaac
    12481 cgaagagcga atcatgcagc taccagagga agagcgtgca gcggctattg ctaatgttta
    12541 tgcacaaaag cagccgattt caaacattac agagcattat gatttaattc ttaatttggt
    12601 ggacgtcaat tctggaggta cagttcagcg tattatctgg ccagctgcta agggaacacc
    12661 ggatcagcca ttctacgtcc atgaggtccc aacaatcgtt gtttcagttc agcatgcctt
    12721 tgcccttgct gatatgccac aggttggtac ttatattaat gcctacgatg gcaaggacaa
    12781 cactatgaag gctttggttg caaaattagc tggtgaatct gaattcactg gagtgtctcc
    12841 tgttgatgcc ttttgtggct tgattgatac ccagctatgg catagcttct gaggttgcta
    12901 caggataagt agaggcttta cgtgttctgc ggtgattgct ctgaatgatt taaaaagatt
    12961 tcaggataaa acctgttaat cagccccttg tagctgcaga aatagcccca taatccctgt
    13021 ggtggggagt tttatccgat atggagatga tagagcctgt taatcctaaa gaaaagctag
    13081 agggtcattc tagcttttct ttttgtgcct aatgctcaac cttgcttcag atgatagaca
    13141 agctataagc ttgttgataa gtgaaacaat tgaacagat
//
LOCUS       DARYLD010000054        12798 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYLD010000054 DARYLD010000000
VERSION     DARYLD010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12798
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            61..345
                     /locus_tag="TU651_001519"
     CDS             61..345
                     /locus_tag="TU651_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0897500.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            354..839
                     /locus_tag="TU651_001520"
                     /pseudo
     CDS             354..839
                     /locus_tag="TU651_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            891..1178
                     /locus_tag="TU651_001521"
     CDS             891..1178
                     /locus_tag="TU651_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL0897501.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            1193..1483
                     /locus_tag="TU651_001522"
     CDS             1193..1483
                     /locus_tag="TU651_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897502.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            1476..1838
                     /locus_tag="TU651_001523"
     CDS             1476..1838
                     /locus_tag="TU651_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0897503.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            1838..2194
                     /locus_tag="TU651_001524"
     CDS             1838..2194
                     /locus_tag="TU651_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL0897504.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            2538..4082
                     /locus_tag="TU651_001525"
     CDS             2538..4082
                     /locus_tag="TU651_001525"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL0897505.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            4084..5943
                     /locus_tag="TU651_001526"
     CDS             4084..5943
                     /locus_tag="TU651_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0897506.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVVNFRR
                     GSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVPKGTV
                     IVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFARGST
                     LKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQYAYFR
                     DKLLTFTAEGVYTDSTVQYRQDLIRLLTWVFGPIKVELGAVCDVVRGNGLQKKDFVNE
                     GYPVIHYGQIYTFYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALV
                     WEGAEDVCIGGHSCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKA
                     IIILPPVYEQGRIVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            5958..7166
                     /locus_tag="TU651_001527"
     CDS             5958..7166
                     /locus_tag="TU651_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0897507.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            7169..10264
                     /locus_tag="TU651_001528"
     CDS             7169..10264
                     /locus_tag="TU651_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL0897508.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            10432..11883
                     /locus_tag="TU651_001529"
     CDS             10432..11883
                     /locus_tag="TU651_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL0897509.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
     gene            12245..12532
                     /locus_tag="TU651_001530"
     CDS             12245..12532
                     /locus_tag="TU651_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL0897510.1"
                     /translation="MATLIRDRQYNFRVNTEMMEEAKRILEAKNISVPDALNLFVERV
                     VEEKDLPIKTAEQIRAESFLNELISELDEGYQDILAGRTKPANEVFSKYGL"
     gene            12522..>12798
                     /locus_tag="TU651_001531"
     CDS             12522..>12798
                     /locus_tag="TU651_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL0897511.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILR"
BASE COUNT         4172 a         2034 c         2795 g         3797 t
ORIGIN      
        1 ataataaaat atacaaattt cggagtttat ttaattgaga aatggaaacg aggtaatgat
       61 atgtctgaag aagcgacttt agttgttcaa cttcccaaag ttttggaaaa acaattaagg
      121 gcacattatg atgaaatggt ttctacagct attgaaagag cgctagagga taaagaatta
      181 tataaaccta tggttcggat ggcagccctt tctagatggc ttgatgtgtc aacgacaaca
      241 cttcaaaagt ggacgcgaga aggaatgcct acaatggtta ttgatggtgt gactctgtac
      301 gataaacgtg cggttacacg ttggttgaag caatatgaaa gatgaggtaa agaatggcta
      361 atagacgaat gttgagtaaa acggtggtgc agatacaacg atttttacgc ctaccacttg
      421 aagcgcaggc gctttactgt cacttggtag tcaatgcaga tgatgatggt attgttgaag
      481 cttttcctgt tatgcggatg attaatgcta atgaggacag tttgaattta ttaactctta
      541 agcagtattt actcttgtta aacaatgaaa tggtttactt tatcaaggat ttctttgagc
      601 agaataccat caaagcagat cgttacacac cgagtagtca tcgtcaactt cttatagatt
      661 atctgaagga taatcagttg ttggagtgtc taaatctagg accacgcttg attaattatc
      721 ttcaaaatac tcggctccaa gttggagcca gtctggatcc agatgggaac cgcaatataa
      781 ttaaagataa gataagtaaa gataggatag gtaaagataa gttaagtcaa gataagatag
      841 gattagataa tgatccaatc tcatcacaac tgactgatga catctggtta atggaaacac
      901 tatggcatcg agaattaacc caacaggaga aagtattatt agaaggattc gcggttaatg
      961 attctttatt gcagttagct attcagaaaa cagaggagct tgagccaaag aaacaaaaca
     1021 tgagttatgt caaagggata ctaatgaatt gggaagctag agggtttata actgttgacc
     1081 aagtgatagc atctgaagaa gactaccgtc cattagaaat tgcaaatgta gaagtttcag
     1141 aagatttctt agcagctatg gatatatgga aagactaggg gaataatgag ttatgacagt
     1201 atattatcaa ttagaaaata tgttagtggc tgggtttaag tcacaagatg agtacgaccg
     1261 ctatcaggct ctcaagaggg actatgaagg ggagtcagag gactatagct tttcaatcag
     1321 agaaatcaca aatcaacttg aaatcatttg tcagacctca gagaatgatt ttccgaactt
     1381 atcagaagca ttaatgattg attatttaga actggtagga gagttgaaac gatatgatac
     1441 taatcaggca gacaggtatt tagggatggt tcgtcatgtc tgaacgtatc agaactattt
     1501 taaagaagtt ttatgtgacg gaattgcaga atgaagtact taatcaacta gtaaatgata
     1561 caggcttgca aacattctct aattatgctc gtcggatgct ttttaaggaa acatcactct
     1621 ttatgcgatt tgatgaatct cagtttgatg agttgattta ttctttaagg cgtattcaaa
     1681 ataatttaag gcagttatct aaaattgcag agcagtctca agatagtcaa gcctacagag
     1741 ctatggacta tagcagaagg ttagtttcac attatgaaaa gcagttaacg cgttaccaca
     1801 agaaaaagaa acggaaatta ttatctaagg gagcttaatg gataaaagga gaattaggaa
     1861 cgtaattaaa caagtctttt tgtctgaaga agaaaatcaa aaactgttag agaaaatgaa
     1921 gcaagatggc ttcacaaact tttctctttt tgctagaaag caattattaa aacctgattt
     1981 tgaaacttgg ctagttagtt ttccagaata tcagccgctg actggcaggt tactatctgt
     2041 tggtagaaca attaatggca tcgctaaaag cgcaacacag tttggaaaaa tttcccaaca
     2101 tgatttgatg gaattaggtc agttgatgga ggaacttgta gaactggtag agaaacaagt
     2161 gaaggaagac aagcaacgaa tagccaagaa gtgatagtcg ttcagtcatt ttggtagaat
     2221 agttttaaat aaaacaacaa aaacgctgat ggtagtcagc gttttttagc atgtaattgt
     2281 aaaaaatcct tgtacggaca atgtgcggca ccgtataaag tacgggaaat cactaaaaat
     2341 ggagttaggt ctttgcgagc tcagatagtg tatacacact atcgtaaaaa tagaaccatc
     2401 agtaaaggtc agactgacac tttttgattg atgcttatat tttattttgg ggcaaagccc
     2461 caaacccctt gagaaaacgt gtgagaagta gggaaaaatg gtataataga aatattaaag
     2521 actgtgagga tttgaagatg tcagaacaag cacaaaggca agagttgcac cgcaaaatct
     2581 gggcaatcgc agatgatgtc cgtggtgcgg tagatggttg ggatttcaaa caatatattt
     2641 tgggaatcct tttttaccgt tttatcagtg aaaatttcaa gacttatatc gagggtggtg
     2701 aggacttcaa ctatgaggag attccggatg aagtaatcac acctgaggtt aaggatgatg
     2761 cgattaagac aaaggggtac tttattatgc ctgcgcagct tttttccaat gttgtgaaaa
     2821 cagctcgtag taatgacaac ttaaatacgg aactcaagga tatttttgat gccattgagg
     2881 cgagtgctat gggttatgcc agtgaaaatg atattaaagg tctttttgat gacgtagaca
     2941 ccagaagtaa taagctagga agtaccgtcc cagagcgtaa tgaacgctta gcccttatcc
     3001 tagaaggtat tgccagcctt gattttggta gtttcgagga caatcatatc gacctttttg
     3061 gcgatgccta tgagtttctg atttctaact acgcttctaa cgccgggaaa tcaggcggag
     3121 agtttttcac accgcagagc gtgtcacggc tcctagcacg tatcgtcatg ttaggcaagg
     3181 atgaaaagaa caaaatcaat aagatttatg accctgcttg tggttctggt tctctcttgc
     3241 ttcaagccaa aaaacaattt acggagcata ttatcgagga tggtttttat ggtcaggaaa
     3301 tcaacatgac cacctacaac ttggctcgga tgaatatgtt ccttcataat atcaactacg
     3361 acaagtttag cattgagcgt ggcaatacgc tgctggaccc taagcatggc aatgataagc
     3421 cctttgatgc tatcgtgtcc aacccgcctt attcaatcaa gtgggttggt agcgatgacc
     3481 cgacgctaat taatgatgac cgttttgcac cagcggggat tctggcaccc aagtctaaag
     3541 cggattttgc ttttatcatg catagccttt cttatttgtc caataaaggc agagcggcta
     3601 ttgtgacctt ccctgggatt ttttatcgtg gtggagcgga gcaaaagatt cgtcagtatt
     3661 tggtagacgg aaactttgtc gaaactgtta tccaattgcc ggataatctc ctttttggga
     3721 cgtctatcgc tacctgtatc cttattcttg ctaagaataa gccgacaaca gatgttctct
     3781 tcattgacgc tagccagcag ttcaaaaaag aaaccaataa caatgtcttg acagaagaga
     3841 acatcgagaa aattctgaaa agtgttgagc ataagaataa tgaagagtat tttgctcagc
     3901 tcatttccca agaaaaaatt gtggaagctg actacaatct ctctgtatct acctacgtgg
     3961 aaaaagagga tacgcgtgag aagattaata ttgatgtatt aaacaaagaa attgctgaga
     4021 ccgtgaaaaa tattgaccga ttgcgggcag agattgataa gattgtcgag gagttgagct
     4081 gatatgacct acattgatga gatgattaaa gagctttgtc ctgacggagt ggagtggaaa
     4141 gagttgggtg aagtcgttga ctacgaacag ccaacaaagt atatcgtaaa atctaaggaa
     4201 tacagcgatg attattccat tccagttttg acagcaggtc agacatttat tcttggatac
     4261 acaaatgaag taactggtat ttatccagca agtaaggaac atccagttat tattttcgat
     4321 gactttacga cagctagaaa gtgggtggat tttgaattta aagttaagtc ctcggcgatg
     4381 aaactactct ctatcaagtc agaccgtcaa gatgatgttt caataaggta tgtttggcac
     4441 tatttaggaa caataaaata cacaccagaa cagcacgcac gacagtggat agggactttt
     4501 tctaaattta aaatccccct tcccccacta gaaattcaag gggagatagt taaaatactt
     4561 gacaaattca cggaacatgt tacagaattg accgcagaat tgacctttcg acagaaacaa
     4621 tattcttatt ttagagataa gctcctaagt tttgatgatg aaagtatggg aggggcgaac
     4681 gataaggttt acactgtcca gtggaaaacg ctgggggagg tggtgaattt taggagaggg
     4741 tctttccctc agccttacac agatatgtcg ttctatggtg gagaagatgc ccaaccattt
     4801 gttcaagttg tagatgttgc tgatgaagga tttagactga atactaaaac gaaaaaaaca
     4861 atttctcaaa aagctattcc aaaaagtgtt tttgtaccta agggaaccgt tatcgttacc
     4921 ttgcaaggca ccctaggaag ggtagcggtt acccagtatg atgcttatgt cgatagaacg
     4981 ttagcaattt ttgacggtta taagcaagaa gttgataaac gctatttcgc acaccaattg
     5041 aagtttattt ttgacagaga aaaagaattt gctagaggaa gtactctgaa aacaataaca
     5101 aaacaagaat tctcgaattt caaaatccca gtccctcctc tggatattca gcgtcgtatt
     5161 gtccaagttt tggataattt tgatacggtt tgtaatgacc taaatatcgg gctacctaag
     5221 gagattgagc ttcatcagaa acagtatgcc tattttagag acaaactctt gaccttcacc
     5281 gccgaaggcg tgtatactga cagtacagta cagtacagac aagacctaat taggctcttg
     5341 acttgggttt ttggaccgat taaggttgag ttgggggctg tctgcgatgt ggtgcgtggg
     5401 aatggtttgc aaaagaagga ttttgttaat gagggttatc ctgttattca ttatggacaa
     5461 atctatacct tctatggatt gagtgctcgc gtgacgaaat cttttgtgtc accagaagtt
     5521 ggtcaaaaat tgaaaaaagc taaaactggt gatgtgattg tagctactac ttctgaaaat
     5581 attgaagatg ttggtaaagc acttgtttgg gaaggtgctg aagatgtttg tattggtgga
     5641 cactcttgtg tattgcacac ggaacaaaac tcgaagtact tgctttatta ttttcagaca
     5701 actgtgtttc aaaagcaaaa ggaaaagtta gtgataggaa ctaaagtgat tgaactgtat
     5761 cctaaaaatt tagaaaaggc gattattatt ctcccacctg tatacgaaca agggcgtatc
     5821 gtctccattc ttgacaaatt tgatacacta acttctgacc ttacccaagg tcttccgaaa
     5881 gaaattgagc aacgacagaa acagtatgag tattggcggg atttactact taactttccg
     5941 taggaggaag aatagatatg ggaaatgata tcaaatttga aaatttagaa cagatttcgg
     6001 ataatattat ttctagtaat aagaaagttc atttgctata tgcctataat gctactggga
     6061 aaactaggct ttctatggaa ttgaaaaata aggtaaatga gactgatagt gatggtaata
     6121 gcattaagca cattttatat ttcaattcat atacggagga tctttttacg tgggataatg
     6181 atttggaaaa cgatgaagat cgatatttga tttatgataa acgaacttat tttggaaatt
     6241 tccttgaaga gcaacaactt ttcgaacgtg ctgtagacaa ttttcaaaag tatgttggta
     6301 gatctattga tattgagttc caagatgtta ttgaaacagt taaagatgag ttcggaaatg
     6361 ttcaaaaaga taataggggt gaggcactaa caattagtaa taaaaagagt ataagattta
     6421 aagtagatgg gcatacaata aaggtgtcta gaggagaaga gaggattttt gtttggtcag
     6481 ttttcttaac gctccttgaa attattattg aagatttgac tgagtctgct gatacctcag
     6541 aattttcaaa aatgaactat atctatattg acgatcctat atcttctttg gatgatacta
     6601 atattattaa tgctgcaatt tatttgagtg atgttatagg tagtgctgaa aatactgatt
     6661 tgaaatttgt cgtctctact catcaagcat tattttataa tgtactttat aatgaaatcc
     6721 gatttgatag aagaatcaag aaaaaggttt tttacgtcat gaaagctact gatgaaattg
     6781 aggatgagaa acaatttaaa tatttgttga cagatgttga aggggattct ccatttggat
     6841 atcatctcag agtgagagaa gaattgagaa aagcaattca agatgaacag gtagagaaat
     6901 tccattttgc tctttttaga aacctagttg aaaaaacagc aacattttta ggatatggac
     6961 gatgggaaaa tatcttgtta ggtttagatg ttgctggaca tgttataaca tctgaaaata
     7021 ttaaactcta tacacaactg attgatttat acactcataa taggcatgct gatttagaat
     7081 atagagaatt gcctccccaa gagaaaaata ctcttataaa tttatttaat agctttgatt
     7141 caatctatcg atttaaagag gactaactat gactgaaatc atccaaacag atactatttt
     7201 agaggctaag aacttcattg tactggaaaa atacaccaag ttggaaaagc ctagcaccta
     7261 tcagacggaa gcagacttgg agcgagagct ggttagcgat ttgcggcagc agggatacga
     7321 gtacctcaac aatctgacga ccccagaagc tctcttagat aacctaaaga cccagatgga
     7381 agcccttaat ggcgtggttt tttctgaggc agaatggctg cgttttttag aggagtacct
     7441 caataagcct agtgatggtt tgattgaccg cacccgaaag ctccacgata accacatcta
     7501 cgactttatc tttgacgatg ggcatatcca aaatatttat ctctgggata agaaaaatat
     7561 cagtcgaaat aagcttcagg tcattaacca aatgtctcaa gttgggactt caagtaaccg
     7621 ttatgatgtg accattttgg ttaatgggct acccttagta caaattgagc ttaaaaagcg
     7681 tggggtggct attcgtgagg ctttcaacca ggttcaccgt tacagtaagg aaagctttaa
     7741 tgaggaaaat tcgctcttca agtatctcca gatttttgtc atttcaaatg ggacggatac
     7801 tcgctatttt gctaatacca ctaagcgaga gaaaaattct tttgacttta ccatgaattg
     7861 ggcactaaaa aataatgagc caatcaagga tttgaaggat tttacagcga ccttcttcag
     7921 tcagcagaca ctcttaaaca ttctcatcaa ctactcagtt tttgatacta gtgataccct
     7981 cctaatcatg cgtccctatc agattgctgc gacggagcgc atcatctgga agattcgttc
     8041 ggccattgat agcaaaatca agagtggtcc tgagactggc ggctatatct ggcatacgac
     8101 ggggtctggt aagaccttga ccagttttaa ggctgcgaga ctggcgactg agatggataa
     8161 agtggacaag gttttctttg tggttgatag gaaagacttg gactaccaga ctatgaaaga
     8221 ataccagcgt ttttcacctg actcagttaa tgggtcaaat agcacagctg gacttaaacg
     8281 caatatcgaa aaagatgaca ataagattgt tgtgacgacg attcaaaagc tcaataactt
     8341 tatgtctagt gaagcacagc atgagattta caacaagcaa gtggtcttta tctttgacga
     8401 atgccactgt tcacagtttg gcgaggctca aaagcgctta aaacaaaagt ttaagaagta
     8461 ttgtcagttt ggttttacag gcacgccgat taaagttgaa aatgctttag gcagtgagac
     8521 gacagcttct gtattcggtc gggagcttca tgcatacgtc attactgatg ctatccgtga
     8581 ccaaaaggtg ttgaaattta aggtggatta taatgatgtt cgtccacagt ttaagtcgtt
     8641 agaaactgag caagatttag ggaaattatc tgctgctgaa aataaaaaag ccctacttca
     8701 tccaacacgg attacagaga tttcggctta tattttagaa cattttaatc aaaagacaca
     8761 taggcaaaac ggtaaaggat ttaacgctat gtttgctgtg tcaagtgtcg aggcggccaa
     8821 ggcttactac caagagttgc aagaccaaca agctggaaaa gctaaaccat tgaagattgc
     8881 aaccatcttc tcttatgcag caaatgagga gcaggctgcg attggggaga ttgatgacga
     8941 gactttcagc cctgctgact tgtcagatat tagtagtaag gaatttttga gcggagcgat
     9001 ttccgattat aatcgccttt ttcagactaa ttttagtatc aatggcaatg agtttcaaaa
     9061 ctattaccgt gatttagcta agcgagttaa gtctggagaa gtggatttgc tgattgtcgt
     9121 tggtatgttt ttgactggtt ttgatgcacc aaccttgaat actctttttg tggataaaaa
     9181 cttgcgttat catgggctta ttcaggcttt ttctcggacg aatcggattt ataatgcgac
     9241 aaagacattt ggaaatattg taactttccg tgatttggag aaggctacga cggatgctat
     9301 taagttgttc gggaagacgg agacggctga tattctgtta gagcgctctt acgaggacta
     9361 catgaatggc tacattgagg ctggtcaaga gcaaaaagga tatttggaag tcgtaaaaga
     9421 attgcaggag agatttccag atccaacgac tattatcaaa gaaagtgata agaaagaatt
     9481 tgtgaccttg tttggtcagt tcttgcgctt ggataatatc ttgcagaact atgatgattt
     9541 catgagtttg caggctttgc aagagttaga tgttacagat atagaggctt tggcagattt
     9601 caaaggacgt tttcatttgg atgacgaagc agttgcagta ctctctcaac tggacatccc
     9661 aagtgttcgt gagattcaag attatcgctc cgcttacaat gatatcaagt cttggtatga
     9721 caatgagcgg cgtaatcagc agaataacga ttccgaaatc gactgggatg cggttgtctt
     9781 tgaagtggag ttgttgaaat cacaggaaat caatctggac tatattctgg aattgatttt
     9841 tgaaaccaac caaaaggtat ctgacaagga tcaactcatt gaagaaatta cacgaactat
     9901 ccgtgctagt ctgggtcaga gagctaagga aagtttgatc gtggatttta tcaatgccag
     9961 tgacttggac agtttttctg agaagtcaga tatcttggag caattttata catttgcccg
    10021 tcaaaaacaa aaagaagcag tggctaattt gattgagact gagggattga atgtagagag
    10081 tgctagccgc tatattcaga tgtcactcaa acgagagtat gccagtgaaa atggtaatgc
    10141 tctcaatgaa gcacttccta agatgagtcc gctcaatcct caatatcgta ccaaaaagca
    10201 gatggtgttt gaaaaaattg tggatttggt ggagatattt aaggggattg gtggagaaat
    10261 ttaattatta ttatttcttc tagatataga agagataaac tttaaattag agcttgaaat
    10321 tttaagaaat attaaggcat catatcagta gtataaaaag ctgacttata atttatttgg
    10381 aaacgacagt taatcctaaa atacgatgct tgatatggag gaggcttaaa cttggaaaat
    10441 aaaaaggatt taattcaaac cttagcctac taccaattct cactagaaaa ccaatacttg
    10501 gatagaaaat cagcacgaaa gaagccgcaa gaattactca agcatctgat tgcttttgcc
    10561 aatgcggacg gcggtcagtt ggttattggt attgaagatg agaagcagga caatattatc
    10621 actggtttca aggatggcag agcttatccc atagacgatt tcaaaaaaat tgaccatgag
    10681 atgcgggaga ctcctctgga tttgtcttta gaggaaatcc ctgtgctaaa tcataaggga
    10741 gaagatgacc tgattttggt tatttctgtt gaattatcgt cgaaccgagt gattgctgcg
    10801 cctaatgatg aggtttatct gcgtcagggc gatgaatcgg ttaaattaag ctatgagcaa
    10861 cgtactcagc ttagctatga taagggccaa cgtttctttg aagatgaagt ggtacctgat
    10921 gcgaccttgg aagatattga tgatgggtta gtccaggact tcaaaaatcg gtttgatatt
    10981 tcagagcgct ccatggaaga agttcttaaa gcaagacgat tcttggttaa tggtaaatta
    11041 actaaggcag cgattctact ctttgccaaa tatccatcag cgttttttcc acaagctcgt
    11101 gttcgttttc aacggtttga cgggacggat atgggaacag gcagtagctt taatgttatt
    11161 aaagaagtaa cttttgatga tgctctgccc accttaatta tcaaagtgcg agattttatc
    11221 cgtactcagc tgcgtgaatt tcagtactta gacgataatg ggcaattcca gattttgcct
    11281 gagtatcctg aatttgcttg gtttgagggt gttgtcaatg cggtgactca ccgtgattac
    11341 tctgtctatg gggatcacat tcgtgtactc atgtttgatg atagactgga gattcatagc
    11401 ccagggaaat taccaaatat cgttaccgtt gacaatatca agcatgaatg tttttctaga
    11461 aatcctcgga ttgcgagaac cctgactgaa tttggatggg ttcgtgagat gaatgaagga
    11521 gtgaagcgta tctattctga gatggaatca gcttttcttc atgaacctaa atatttagaa
    11581 ccaggtaata aggtagtttt gacccttgaa aataacatcg tgagtcgaca tctccgaaca
    11641 cgagatagtt tggaaaaaca attttctgat tttggaaatc tgactgcaga tgaacaagct
    11701 atcgttcact acatgtataa ttctggcgat aaaatgacaa cagcaaaggc gattgagttg
    11761 acagggagaa gtcgttcgtt tgttgtcaaa atgctacatc atcttcgtga tttagaaatc
    11821 atcacttggt ttggttcaag taaaaatgac cgtaatcaat attatctttt agttgataaa
    11881 tgattgcagc caggatactt attagtaata agaatacagt agaatacaga aaaagtggtg
    11941 ttccataaaa tattgatcac cacttttgat tatagaagtt taaataaagt ggatatttgt
    12001 atatagttca caatatatac ctcaaataca ataagaaata gtggttatat ttttctgtta
    12061 ttgtagatat ttaaaaatag ttgataagtg attacattta gcatctctca actgataaat
    12121 tccgaaaaca tacttatttt tagtaaacta atggcaagtt tgcaaattgc tttatattgc
    12181 taagtcacta ttgatttgtt ataatcttgt tatacataag gataacgcaa ttaaggagac
    12241 tataatggct acattaataa gagatagaca gtataatttt agagtaaata cggaaatgat
    12301 ggaagaagca aagcgtattt tagaagctaa aaatattagt gttccagatg ctcttaatct
    12361 atttgttgaa cgggtggtgg aagaaaaaga tttacctatt aaaactgcag aacaaattag
    12421 agctgaatca tttttaaatg aactgatatc agagcttgat gaagggtatc aagatatttt
    12481 agcaggacgt acgaagccag ctaatgaggt attttcaaaa tatggcttat gatatctata
    12541 tttcaaataa ggcagaacaa gatttagatg aaatctataa ctactattta acagaatttt
    12601 cgcactcaag cgctcaaaaa gttattgaat ctttgcagtc agctatttct attcttgaga
    12661 tatcccctga aggttatgtt gattttgacg atcgtgtagg acgtaaacta tttcctgaag
    12721 gccagctaag gatgattcct agtaagcatt tcatagtatt ttatttaatt cgtcagtcaa
    12781 gggtagatat tcttcgta
//
LOCUS       DARYLD010000055        12772 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYLD010000055 DARYLD010000000
VERSION     DARYLD010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12772
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..279
                     /locus_tag="TU651_001532"
     CDS             <1..279
                     /locus_tag="TU651_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEL0897512.1"
                     /translation="SKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLS
                     AYIKSTGKTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            276..1050
                     /locus_tag="TU651_001533"
                     /pseudo
     CDS             276..1050
                     /locus_tag="TU651_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            1047..1532
                     /locus_tag="TU651_001534"
     CDS             1047..1532
                     /locus_tag="TU651_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL0897513.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            1529..3000
                     /locus_tag="TU651_001535"
                     /pseudo
     CDS             1529..3000
                     /locus_tag="TU651_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001899253.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            2954..3310
                     /locus_tag="TU651_001536"
     CDS             2954..3310
                     /locus_tag="TU651_001536"
                     /inference="COORDINATES: protein motif:HMM:NF014581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HEL0897514.1"
                     /translation="MERKKTLKELSETLGKETIDLYNTSETRSNQKSFGLNYQKTGKE
                     LMSQDEITVMDGGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDKKNLFDIESYMKR
                     KGKAKLNRETVITRMQ"
     gene            3474..3785
                     /locus_tag="TU651_001537"
     CDS             3474..3785
                     /locus_tag="TU651_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0897515.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            3789..4004
                     /locus_tag="TU651_001538"
     CDS             3789..4004
                     /locus_tag="TU651_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL0897516.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            4024..4890
                     /locus_tag="TU651_001539"
                     /pseudo
     CDS             4024..4890
                     /locus_tag="TU651_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4910..5173
                     /locus_tag="TU651_001540"
     CDS             4910..5173
                     /locus_tag="TU651_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0897517.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            5177..5566
                     /locus_tag="TU651_001541"
     CDS             5177..5566
                     /locus_tag="TU651_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL0897518.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            5478..7907
                     /locus_tag="TU651_001542"
     CDS             5478..7907
                     /locus_tag="TU651_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0897519.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            7911..10034
                     /locus_tag="TU651_001543"
     CDS             7911..10034
                     /locus_tag="TU651_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL0897520.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            10047..10286
                     /locus_tag="TU651_001544"
     CDS             10047..10286
                     /locus_tag="TU651_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0897521.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            10261..11808
                     /locus_tag="TU651_001545"
     CDS             10261..11808
                     /locus_tag="TU651_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL0897522.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            11904..12680
                     /locus_tag="TU651_001546"
                     /pseudo
     CDS             11904..12680
                     /locus_tag="TU651_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
BASE COUNT         4836 a         1872 c         2817 g         3247 t
ORIGIN      
        1 agtaagagag aatataattt tagtgaaaac gggcttggaa catttcaaaa tgtgttttta
       61 gctgctgaag atatatcaga cttacaaatc ataatgaact cacagcttga taattatatt
      121 gagagattat ctgcatatat taaaagcacc ggaaagacct ataaagacca taaggcaaca
      181 atcctttcat ggttttataa agatcaggga aggggcaaag aagtgaaaac atcaaatatc
      241 ccgacatggg aagaatatga taaaggagaa cacctatgat aaaagaatta gaaaaagtaa
      301 tgatagagga tgtagagtat tcttacgatc ctgaaaaaga atatatcaag gacggacacg
      361 ccttttgtaa agtttgtcat gaaagaaaag acagaaaagt gatggagttc tttgataaca
      421 agatgatatt taagatttct tgcaaatgcg atagagatag agaggcaaga aaaaaagaaa
      481 gagaaaagca gatggaaata gaacgattaa aaaagaactg ctttaactct attattcagt
      541 ggtcatacac ctttgaaaat tatcagggag aagaaaatca aagtcttatc attgcaaaga
      601 attttgtaaa agactatgag cagatgaaaa aagaaaatat cggactgcta ttttacggct
      661 cagtaggaag tggaaaaacc tatcttgcct gctccattgc aaatagcctt attgaacagt
      721 atcaaatagg cgttaaaata agaaattttg cacagcttat caatgagctg caaaagggag
      781 gatttgattt tgataagaac gcatatattg aatcccttgt aaatacttcc gttcttatct
      841 tggatgactt gggaatagaa agagatacaa gctatgccaa agagcaggta tataacattg
      901 tcaacaacag gtacttaaag cagaaaccga ctatcttcac cactaacctt tcctacgaca
      961 caatccaaag aggattttag aaagattatt caaagagata aattgaatcg aaataaagat
     1021 aggttactga atggaggtga gagaacttga tcaatgaaga aatagcaaga aaaacgctga
     1081 atatggaagt aagagctgct aaagtaacag gaaagttaat tctgaactta ttaaagaaat
     1141 tgatgaaaga agcagaaaaa cttggaggac ttgaaaagct ggttaatgct aacggaaatg
     1201 aagtaaagct aaaagatatg gtaaaaaagg gacagcttga agaaattcct gttgaagaag
     1261 cggagcttaa ggaactgaaa aaagaactta atcggtatgg tgttaagttt tcagtgatga
     1321 aggataagga aacaggaaaa tactctgtat tctttcaagc caaagatatg aaagtgatgg
     1381 ataaagcctt taagcacgca ttagcacagt ctgaaaagaa aacggaaagg aaagaatcta
     1441 ttcacaagaa tattgagaag tttaaggaaa tggctaagaa ctctgtttcc aaagataaaa
     1501 tcaagaataa acaaaaggag cagagcctat gatagataaa atattaaagg acatcaaagg
     1561 cttatttaag gtgcaggata agacaaagtt tgtaaagcaa aacattccct atcttgcatt
     1621 tttctattta ggaaacatct ttgcccatca tgtgagaagc tataccggtg gtgatgtcat
     1681 agataaaatc tttcaaggga tattggagat caacacgatg agttttcttc caagtattca
     1741 tccggcggat attttaatgg gcataggaat ggctgcttta attaaattta ttgtctatac
     1801 caaaggtaaa atgctaaaaa gtttagacag gggaaagagt atggctcagc aagatgggga
     1861 aataagaaag atattgagcc atacatggat gaaaagtttc aaaacaatat cttgcttacc
     1921 cagacagaac gcctaactat gaatggtaga ccggctaatc caaagtatgc tcgtaacaag
     1981 aatgtacttg taatcggtgg atcaggaagt ggtaagacaa gattttatgt aaaaccgaac
     2041 cttatgcaga tgcacagtag ctattgcgta accgatccga aaggaacgat agtcattgaa
     2101 tgtggcaaga tgcttgaaga caatggatat gagataaaaa ttctaaatac cataaacttc
     2161 aaaaagagca tgaaatacaa tccctttgcc tatatccatt ctgagaaaga tatactcaaa
     2221 ttagtgcaga caatcattgc aaatacaaaa ggtgagggag aaaaagcggg tgaagatttt
     2281 tgggtcaaag cggaaaaact ctactacaca gcacttatcg gatatatctt ctatgaagct
     2341 ccaagagaag aaaagaactt tgcaacgctc cttgatatga tagacgcttc agaagtaaga
     2401 gaagatgatg aaacctatat gaatccaata gacagactct ttgaagcact tgagaaaaag
     2461 gagcctacgc actttgcggt caagcaatat aaaaaatata aattggctgc gggaaagaca
     2521 gcaaaatcta ttcttatatc ttgtggtgca aggcttgctc catttgatat tcaggaactt
     2581 agagatttga tgagtgaaga cgaacttgag cttgatacat tgggagatag aaagacagca
     2641 ctctttgtta ttatctctga tacagatgat acctttaact ttgtagtgtc tattatgtat
     2701 tcacagttat ttaatctact ttgcgataag gcggatgatg tatatggtgg cagacttcct
     2761 gttcatgtaa gatgcttact tgatgagttt gcaaatatcg gcttaattcc aaagtttgag
     2821 aagctcatag ccacaattag aagtagagaa atttcagcga gtattatctt acaggcacaa
     2881 tctcagctaa aggcaatata taaggataat gctgatacca ttgtgggtaa ctgtgatagt
     2941 accttattct taggtggaaa ggaaaaaaac actaaaagag ctgtccgaaa cgcttggtaa
     3001 agaaactatc gacctttaca acacatcgga aacaaggtca aatcaaaaga gctttggact
     3061 taactatcaa aaaacaggca aagagctgat gagtcaggat gagattacgg tcatggatgg
     3121 tggaaaatgt atctttcagc ttagaggtgt cagacctttt ctttcagata agtacgatat
     3181 tacaaagcac aagaactata agctgcttga ggactatgat aagaaaaatt tatttgatat
     3241 agaaagctac atgaaacgga aaggaaaagc aaaactgaat agggaaacag ttattacaag
     3301 aatgcagtaa gtctacaaaa tagatttgct gcttttttat gcaaaagtaa ggaggcaaga
     3361 tgataaggat cagaagtccc actgagtaaa aaactaaata gtatgagtat agcgattgga
     3421 aaagtaatac ttccggtcgc tttttttatt gaaatgaaaa ggagaaattt ttaatgaagc
     3481 aagaaatgat taacatcaac gccaacttag tggcagaacc tactttctca agttttgaaa
     3541 aagagggtaa agaagtagaa gttgtaaatt ttacgcttgt aaagaagtac ggtaaaggca
     3601 aggagtacat caattgtgca gcctatggag aaaaagcgga taaagcaaag gactttgaaa
     3661 agggcgattt gattcatgta ttcggctact ttaagaagcg tgaaaaagag ggaaagactt
     3721 acaaaaattt tgtagtgaag tcatacaaca agattgaaaa gaaagaagaa aatgaggagg
     3781 aataaattat ggaatttttc gcacaggcag taaatgtatt aaagattttg gttatggcag
     3841 taggagcagg acttggagca tggggtgtca ttaacctgat ggaaggttat ggtaacgata
     3901 atccgggagc caaaagtcaa gggatcaagc aattgatggc gggaggaggt attgtcctta
     3961 tcggacttaa gctgattcca cttcttgcaa atgtactcag ataagaagaa aaggagagct
     4021 tagatgtttg ggatattcga caaaatagaa gaattcttta aggagcttct actgggcggt
     4081 atccaagcaa acttagagtc catgtttctt gacatcaacg acaaggttgg tgcagttgca
     4141 acagatgtag gaaaaactcc tatggggtgg aatggagatg tatttacctt tattaaaagc
     4201 attaacgatt cggtcattat tcccatagcg ggactaatta tcacagcagt cctttgtatc
     4261 gagcttatca atatggttat acagaaaaat aacctacatg ataatacgga tacatttgaa
     4321 tttttcaagt acatcatcaa gatgtgaatt gctgtatggt tggtatctca cgcttttgaa
     4381 ttttcaatgg cggtctttga tgtagcacag catatggtaa ataaggcggc aggggtgata
     4441 aacacctctg ccaccgtttc cggagatcag atagtggcga tgatggatac cctaaaagaa
     4501 aagggacttg gagagcttat catgattctc tttgaaacct cgctcattaa agttgccata
     4561 caggcaattt ccatagtgat tatgcttgtg gtttacggaa ggatgtttga gatttatgtt
     4621 tattcatcgg tttcagccat tccatttgcc acgatgggaa acaaagaatg ggggcaaatt
     4681 ggcacaaatt acatcaaagg attatttgca cttggactac aaggactctt tttaatggtt
     4741 tgtcttggaa tttacgcagt attagttaag acgattgaaa taacagatat acacacaagt
     4801 accatgacga tacttggtta tgcggttttg ctggggttaa tgatgctaaa gagcggaaca
     4861 ctggccaaaa gcgtattaaa tgcacactaa aaaagaaagg aaagatagta tgaataaaag
     4921 aaaaacagta tttacagcag tagtaatggt cgcaggcatt atggcggtaa ttgatagaat
     4981 caggcttcat aacaaagctg ccgaattaga agaaagaaca caggacatcg gtcgctgcca
     5041 taatgatttt tgcttaatgc agcaaagata taacaagaat acagatgaac agcttgcaat
     5101 tattcaggat gaaatcggct ctgtatatga acactttgag gagttttcaa agggtaaaga
     5161 agatgggagg taagctatgg cgtatgtacc aatacccaag gacttaaaga aggtcaagac
     5221 aaaggtagcc tttaacctta caaaaagaca gctcatagga tttaccattg caggacttgt
     5281 tggaatacct gtctatttat ttatgagaaa ggtagtacca aacgatatag ctttcatatt
     5341 ccttatcgtg tccacacttc caatcttttt tatcacactt tttgaaaagg acggactgac
     5401 ctttgagaaa tattttaagc atatctacct tcataagttt tatcagccgg caaagagagt
     5461 gagaaaggag gtttaccttg aacaagaaaa gaaaaattca gcaactaaag ttagaagaaa
     5521 acaaaaaggc attaaaaaag gagagaaagg acttaaagca aagtaaggga aagtctaaca
     5581 aagaaaagag cggactactt gatcttatct ttagaaaaga gcaaaaacgc tatacggtag
     5641 aagataccat tccctatctt agactcttaa aaagcgggat atgccagctc gatgaaaagc
     5701 acttcagtaa aagcatagcc tttcaggaca ttaactatca gcttgcttta gatgaagata
     5761 gggatttgat ttttaatcag tttgcaaact ttctaaattc ctttgatcca agcatagcga
     5821 ttgagttttc ctacatcaat cagcttggac gaaacgaaga aatgaaatcg gcaattcaga
     5881 taccggataa aggggacgga tttgacgata tacgacttga gtttagagag atgctaaaaa
     5941 gtcagattgt aaaaggaaat aacggactga aaaaatcaaa gtatgtaacc tttacagtag
     6001 aggcagacaa tttagaacag gctacatcaa aacttgaaag attggatata gatatattat
     6061 ctaatctcaa aagcatgggg gtaagagctg aaagtcttac agtagaggaa aggctaaaga
     6121 ttcttcacga tatattaaat ccgaataaga cctttgagtt ttcctacaaa gacctgaaga
     6181 aaaaggaaag taccaaaaca tatatcgtgc ctgatgaatt taactttatg ccaagcaggt
     6241 atttcaagtt tgggaagttt atcggagcaa caagtcattt tcaaatcctt gcaagtgagc
     6301 tttcagaccg tatgttatcg gagtttttgg atattgatga taacatcaat atatcttttc
     6361 atattaaggc gattgaccag tcagaagcca tcaagatggt aaaacgaaaa aacaccgata
     6421 ttgataagat gcgaattgag gaaaacaaga aagctgtaag gtcaggctat gacatggaca
     6481 ttcttccaag tgatttaatt acttacggag aagatgtaaa aagtctttta aaagatttac
     6541 agacaagaga tgagcgtatg tttgttgtaa gtattgtctt tatgaatttt gcaaggacag
     6601 tgcaaaagct cgataacacc atagctcaga taagctccat tgcaaacaag cataactgta
     6661 aattgaaaag acttgaccat acgcaggaac aaggcttagt gagcgtgctg cctcttgggg
     6721 taaacaagat tgaaatagat agagggctaa cctcatcatc aacagcagtc tttatgcctt
     6781 ttacaacaga ggagcttttt atcaattcaa gtaatagcct atactatgga ctaaacgctt
     6841 taagccataa cctgattatg gcggatcgaa agaaattaaa gaacccaaac ggtctaatct
     6901 taggaactcc gggtagtggt aagtccttta gtgccaaaag agagatggca aatgcgattt
     6961 tagtaacgga cgatgatgtg attatctgtg atccggaggg agagtatgga aaccttgtaa
     7021 gacagtttaa tggagaagtc attaaggtca gcagtaagtc aaaagattac ctgaatccac
     7081 ttgatataaa tatgaactac ggtgatgggg acgcacctct taaagacaag gcaaacttca
     7141 ttatgtctat gcttgagctt gtagttggtg gtagtggact tacagcggaa gaaaagtccg
     7201 ttatagatag atgcttacct aagatttacg aaaggtactt tgaaaatccg acttatgaca
     7261 atatgcctat acttcaagac ctatacgata tgttaaaagg gcaggaagaa aaggtaggga
     7321 aaaagctggc aacagagatg gaaatttatg tttcaggttc tcttaatgtc tttaatcaca
     7381 ggtcaaatgt ggacttaaat aagaagctac tttgttttga tattaaggag cttggaagtc
     7441 aattaaagaa aataggtatg cttgttatac aggatcaggt gtggaataag gtatcgcaaa
     7501 acagaggaaa caaggctaca aggtactata tagatgagtt tcacttgctg ttaaaagatg
     7561 agcagacagc ttcatattcg gtagagattt ggaagcgttt tagaaaatgg ggaggaatcc
     7621 cgactggtat cacgcaaaat gtcaaagacc tacttatgag taaggaaatt gaaaatatct
     7681 ttgataatac ggactttgtc ttaatgttaa atcaggcttc gggagatagg gaaatacttg
     7741 caaggaaact taaaatctca cttccgcagc ttagatatgt tacgaactcc aatgagggcg
     7801 agggactact tttctttgga aataccattg tgcctttcct tgataagttt ccgaaagata
     7861 caattcttta tcagaagatg actaccaagc ctgaagaagt gaggtagctt atggatggga
     7921 agctgaaaaa agattttaga gaaaggcata aggcaagcct tgaaagggag atgcttaaag
     7981 ctgaaacaag ctctatacct gaagaaagta agctaaagca taacgatgat tacagaggaa
     8041 aaattgtcca tgacaaagat agatttcagg acaaggttca tgagaagata agcaaggtaa
     8101 gatctgaaaa tgagcagata gaggggactt ctaaaagaaa tgcaaagtat agggcttctg
     8161 ataagggaag tgtaaatgaa gcaggaaagg ctgactatga tactgaggta aagaacggga
     8221 aaatctatga ttctttagga caagaccttg ataatgatgg aatcatagac agatacgata
     8281 atgattttag ggacagcgac tactttgaat caacctatga tgtagaggat aatctacctc
     8341 aaaaagaaaa atcattagaa aatccctcta aaaatcataa ggctcaaaag aataagtata
     8401 aaaggaaaaa ctattccgaa agcctctata caagaaaaaa ggacgatgta ccaaaagaga
     8461 ataagcctga agataaaaag gcagggaaag atgttgcggg cgaaaaagaa catagcagtc
     8521 tttcaaaaga ccaaaagaaa aagctgaaga aagatatggt aaaagtatct gccctgtcag
     8581 gacttgccaa aggaagtgaa accgtaagag attacctttc tcatggaagt gatgaaaata
     8641 aaggcgtaga agcgggagaa aaaacagccg atgcaagttc aaaactcatt catggtataa
     8701 agagatactc agataagaaa agagctaaaa aaggatatga gcttacaaat aaggactata
     8761 aaatcagaaa gcgtaaatcc aagttagagt ttcgtgatgc caaagaggaa ctgaaaaaga
     8821 cagatgagta taaaagagca agtgcctata aaagatttca aaagaaaaat caggtaaagg
     8881 cagcgatttc tcgtgagaat aagtcaagac tcagagatcg gattaaagag ggacttatcg
     8941 gaacactgaa aagctcaaag gatatgatta tccgaaaagc caaaggacta atgcttatct
     9001 tcgtaggtat catcatctta ggaaattttg tgattaactt tgcaggaaca ggcatgacag
     9061 gctttatgaa ctctacaaac tctgttctta caacaagcta tttatcaaag ccaaatgttc
     9121 taagtgaaat caatcagaag ttttctgcta tggagagtga gcttcaaagt gaagtggatc
     9181 atgtagaaga gaattatccc ggatatgatg agtatatctt aaacaacaca gagtatatcg
     9241 gtcataatgt ccatgagctt ttatcctaca ttacatcaag gtgcggagag gtaaagagtg
     9301 tatcggaagt agaaaccata ttaaaagaat tgtttgagtc catgtatgac cttgaataca
     9361 gggaagaaat tgaaatcaga tacaggacag ttacagaaac ctataccgat gaagatggca
     9421 atgaatatac cgaaagccat gaagagcctt atgaatataa gaagctcatt gtaacgcttc
     9481 ataaaaaaga gatggacagc attatccgaa gggtctttaa agactatccc gataatttaa
     9541 agcactatga agccttattc cttgctcaag gaaatatggg agaagccttt agaaattctg
     9601 accttatcag tgctaatggc ggtgtaggtg gtgggaaaga gtatgaggca tcttcggaag
     9661 tacaaaagaa gattgttaat gctgcatata tcactccatc tccgggtgca ggctggtgtg
     9721 ccatgtgggt atcgcaagtt taccaaaatg cgggacttgg atatatcgga ggaaatgcta
     9781 atgatatgta tcgaaactat acctttacat ccgataggtc aaagctcaag gtaggaatgc
     9841 ttgtagcggt agaaagcagc agtagcggaa gcacagcagg acttacctat ggtcatgtcg
     9901 gaatctatat cggagacggc aaggttattg ataatatcgg ttatataaga gtaactactt
     9961 tagatgattg gattgcgact ttttgtaaac accatccggt aggctttggt tttccaccaa
    10021 atgtaaacag ataaggaggg aacaatatga aaaaagaact gacagcagta aaaaacagaa
    10081 taaaaaagtt aaaggataaa aaggctctga ttgatgaaga attggagcct ttatttattc
    10141 gtgaagaaga acttgaaaat gaagaaatca tcatgatttg cagaaagaac aacatcacaa
    10201 tttctgattt aatgacaaag gtaaacagag aaaaagcaga actgaaaaag gagaggacaa
    10261 atgaaaacca gtttgaaaaa gaataataag ttttggacag cagcacttgc agtaattgta
    10321 agtattagct gcattttagg actttggacg gttgtttacg ccaaggagaa aagctctgac
    10381 gctcctacaa aaaacgaagc tgtccaaacg gaagttgaag taaatgtaaa gtatatcttt
    10441 gaagatgaaa aggtatttaa ggaagaaaag attaaggcag agaaaggaca gcttcttgat
    10501 agtggcgatc ttccaatgct ccctgatgat atgaaattta ttgatgaatt cctgttttat
    10561 gaagtaaagg gagatggaaa tgatgaaatt atccgtaagg tagcaaagac tgaggttaag
    10621 gataaggaaa cgcaaacgga agaagaaaaa ccaaagcagg acgaaagcac gcaaacagaa
    10681 gctacaaaaa cggaggataa aggcacacag acagagcttt ctaaagacga tatttctaag
    10741 atggaaaaag aggctaaaga gcttcaagaa aaatttgata agttaaatgg tgagcttaaa
    10801 gacaaggata agcagaaaga aaaaatcaaa gaccttgaag atgaaattga cagcctgaaa
    10861 gagaaaatga agaaagataa aggaaataag gacttatcag aagatatgaa aaaggaaata
    10921 gataagctga ctgataaggt gaaagagctt gagaaaaagg caactgaaac aaagaaatct
    10981 tctgaagcaa taaattctgt tacaccgatt agtcctattt ccggaattaa gacaagctca
    11041 agcatttctc cccaaacacc acagacttct gtaagtagtt ccggtaaagg ctcatctgat
    11101 acggtgagtt cagggaatgc tacaaaggat acaagcaaaa cagaagtaaa ggagaaagaa
    11161 aaggaagttc gctattctaa taaattgaca gcaaaagcac ctgctaataa cagcagtcaa
    11221 gattcgtcaa tggagggggc aagtagtaat gtaaatacca ataagggagt agcttcatct
    11281 ccgtcaaagg caagaggaac tgttacagaa aataaagata atggaaataa agattatccg
    11341 attcatcatg gggatagcag cgataataaa gaaacggatc aatattccgc tgatgcaaga
    11401 cagtttatta cctttcaaac taaaaacggt aagacctttc atctcatcat caaccacgat
    11461 gaggatagtg agaatgtcat gcttcttaca gaagtatccg aagatgattt gcttaacatg
    11521 gtagagaaaa aagaagctcc aaagcaggag attgtaaaag aagaacctgt taaggaagaa
    11581 gtaaagcctg agaaaaaaga agaaaagagt aatttaggaa catatattat tctgcttctt
    11641 gttgtaggcg gagcattggg agcaggatac tactttaagg ttgtaaaaaa gaaagaagat
    11701 aaggagcttg aagcattaga ggaagaagat gatgatttct tttctgaagc tgaaagcgag
    11761 gaagaaacaa atgatgtaga tgaagtagaa gcggaagatg agcagtaatg ctgcaccaaa
    11821 aaaatacagt atttggtgca aatgcagggc gggagaataa aatctttcgc ccttttatat
    11881 tgaaaacagg aggcagtaca gaaatgaagt tagtcattgc agaaaaacca agtgtagcat
    11941 taagtattgc aaaagtactt ggagcaaata aaaagaaaga cggatattat gagggaaatg
    12001 gatacaaagt atcttggtgt gttggacact taattcaaat ggcaaatccg gatgtttatg
    12061 atgaaaagta tgccaagtgg aatatggttg atttaccgat tatccccaag gactataagt
    12121 atgaagtggc aaagtcaacc aagaaacaat ttaacatcct taaaaagttg atgaacgaca
    12181 aagaaattga tacggttatc aatgcgtgcg atgcaggtag agaaggggag agcattttta
    12241 gacttgtata taatcaagtg aattgtaaaa agaagatgaa acacctttgg atttcatcta
    12301 tggaagatac tgccattaaa gatggctttg atcatctaaa agacggaaaa gattacgata
    12361 atctctttga gtcggcacag gcaagagcta tcgctgactg gcttgtcgga atgaatatca
    12421 gcaggctcta ttcttgtctg tataagcaaa attacagtgt tggcagagta caaacaccga
    12481 ctcttgctat gatcgtaaaa agagatgatg agatagcaaa ctttaagaaa gaaaaatatt
    12541 atacggtaga gctttctaca aatagcttta cactttcaac agatagaatt gatgatgaaa
    12601 tagcagcaga gcagctctta actttagtgg gcaataagat tgaaataact gatgtcattc
    12661 aaaaagaaaa gattactaaa tgtactgccc ccaaaaagtt ggacgaataa ttattgaaag
    12721 gatttagttc tgtattgcac agggctaagt ccttttagct ttgctttaat gc
//
LOCUS       DARYLD010000056        12359 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYLD010000056 DARYLD010000000
VERSION     DARYLD010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12359
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TU651_001547"
     CDS             complement(44..2632)
                     /gene="hylB"
                     /locus_tag="TU651_001547"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL0897523.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2578..3231)
                     /locus_tag="TU651_001548"
     CDS             complement(2578..3231)
                     /locus_tag="TU651_001548"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897524.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3271..3900)
                     /locus_tag="TU651_001549"
     CDS             complement(3271..3900)
                     /locus_tag="TU651_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL0897525.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3902..4903)
                     /locus_tag="TU651_001550"
     CDS             complement(3902..4903)
                     /locus_tag="TU651_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL0897526.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4936..5577)
                     /locus_tag="TU651_001551"
     CDS             complement(4936..5577)
                     /locus_tag="TU651_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL0897527.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5612..6406)
                     /locus_tag="TU651_001552"
     CDS             complement(5612..6406)
                     /locus_tag="TU651_001552"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL0897528.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6715..7149
                     /locus_tag="TU651_001553"
     CDS             6715..7149
                     /locus_tag="TU651_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0897529.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEAEEADLDEGGI"
     gene            7149..8348
                     /locus_tag="TU651_001554"
     CDS             7149..8348
                     /locus_tag="TU651_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL0897530.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8394..8882
                     /locus_tag="TU651_001555"
     CDS             8394..8882
                     /locus_tag="TU651_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL0897531.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8897..9676
                     /locus_tag="TU651_001556"
     CDS             8897..9676
                     /locus_tag="TU651_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0897532.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9663..10484
                     /locus_tag="TU651_001557"
     CDS             9663..10484
                     /locus_tag="TU651_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL0897533.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10884..11885
                     /locus_tag="TU651_001558"
     CDS             10884..11885
                     /locus_tag="TU651_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL0897534.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3478 a         2845 c         2449 g         3587 t
ORIGIN      
        1 agctcagggg ggattttaac ttattactaa tgtgcttgaa tggctatgat aaggccttaa
       61 aagatagctg cttaaagtca tttcccacct tttgatagag gtataagcct gatttttcaa
      121 gactcaattg accattaacc acctccttag cctgattgta tttgaccacc gccaacaggc
      181 cttgtttctt atcatggatc agctgaagct tactgtcatt tcgaagcacc tcaatacgtg
      241 cttcgctgca caccttgtca aagtctgctt tgctgatatt tggaagtagg gtgtaggcat
      301 agctatcact agcctgagaa tgagtttgac tgattgtgat aaagctttgg gagatgaggt
      361 ctttattgtt actatttgta ttaatctcag accaacagcc tgactgcacc tttcgcgata
      421 gcgctaatgc ggttggcttg gcaaaaaggt aaccaatatt agcttgaccg tctttagaaa
      481 gtagtaaaag actggtcaca tcatctcgat acaggatctc ctctgttagc gctgtctcct
      541 gcccattgat aaaaagagtg tagctgttgt ctgggttttc tttgcgttga tcaatggtag
      601 tagtcactgc ctgatgtgtc tgactagtga tggcggtgcc aagaaaaaca atttggtcat
      661 ctaagatcgt ccaagacttc ttggcactca ctgtcctatc ccaattttga aaatccataa
      721 cagctaaagc tgttttgtct cccgccttga tcgctccaac aaaggacgat ggcagggtag
      781 acatgcctgc tttttctttg gccttttctt tataatcatt ggttagcttt tttaaatagg
      841 ctactgtcac gtcctctcgc ctgacctctg cttccgttgt tccagccatc tttaaaggat
      901 taacagtcgg ccaaaagtgg tctgagtaat gacccaaatc actgttataa aggtaaaaca
      961 tgccatctcc tgtataccaa ccacgtgtat tttcatcgtt catggcttca aaattcagag
     1021 ttttgttgga atgcatggat aaagcaaagg caaaatcctt ttccgcattg tagtaggcca
     1081 atttatccat ctggttaaaa agagataggt agctcttaac tggactggct tggattgtgg
     1141 tatcctccaa gagctctttg aatagcttca tgtcatagta gcttgatagg ctctctaaaa
     1201 tagtctcctg attatggaag gccaaaacag ccttgatctt acccttgatc ctgattttag
     1261 cttgctctgg caatgcctca gccagtctta gcattcctct tagtgcttct aaggctgcct
     1321 gccttgagga ggcattttca cgactgatgg agcgcccacg actcatatcc atgagctccc
     1381 catgaaccat caagggcaag aaggcttgct caatccaatg agtcatgacc tctagctttt
     1441 gctggtctag gctagtagct aatagctgaa gtaatggtac cagctgagac aagccatcaa
     1501 taaggacatt gccataggct ccagtgtagg cgacattggt atggtcaata taagagccat
     1561 cttcataaaa gccctcaccc cttgatccct ttggctgaaa agcaaataag gtatctaggg
     1621 ctgctatact gtcttgaagc gctttcttat catgctttaa cagagcttca ataatcttca
     1681 ctcgtcccat atcaacaagg ttacccccaa tggccttaaa aggattcaca agggttaagc
     1741 gaaattgtct aggattagga acaaagtgag aaattccttt agtatagcgc ttgatctcct
     1801 cttgagtgac ataagggtaa atgaaggcta gggtattgac aatagctctt ggggtaccaa
     1861 tttcaaaatc ccaccaatta gccttgcctt caatatcctt ttgcggatga tagtaattaa
     1921 gtgtcagcca ggctaattta tccttgatca gtcttatcag ctccttatcc tgataatacc
     1981 tagaggctag gctactcacc tgcttggcca tttcctctaa acgcctacag gtagctgtca
     2041 tatgagacga ttgatgaaga tccgccaaat cactccaaag gtatgtgctt ttctgatcct
     2101 tggtcagatc agctagattc ttggtcacgc tgtcgtccag tttttggttt aatgccacca
     2161 tggctggact tgatcggtca aagttttctg ctcccaaaat cacctcacac cactttgtga
     2221 tcaaggaggt tgtttgaggg gcttctgctg ctaaaatctc aactggtacc gttgctactc
     2281 tttgcccctc ttgatccaac acctctaaaa gcgttttccc ctgcgccaaa ggaattaaaa
     2341 gaccattttc cacgcgcaca atgttgctgg actccgctgc aatctgataa tgatagtcag
     2401 ccatttccat gaggtagtgc ttatttaaag gcaggacgat ttgctcctct aagtaatgtg
     2461 aagcaatctt gatgtcatca cttggcttat caccagcctc tctcaaagaa aggttatcaa
     2521 agaccacctg tccatgaccg gcctcataaa agagctctag cttgatttga ttaaccttta
     2581 gcttagggat ataaagcttt tcttggtgtt ttttctcagt tcctgttgcc atcgaagcca
     2641 caagcgttgc tcttttgcag caccagaacc ttgctttatt tcttcaatga tacgcgcaaa
     2701 agcctgacct gttttatcct ttgtctcaat gtcaaaggtc agcaaatact gcttgtctgg
     2761 attgatggca acggtttggt gcacacagcc tctaaatctc tgattgccat cgctagtcat
     2821 tgtcagcttg ttatcagaga cagcaatttt aggacagccc tgactcttac tagcgtcctt
     2881 ataatccttc caatcatttg cagactcctt gctccaaagg cttgtacttt gatgctcttg
     2941 agcaggactg gtctgatcaa attgaggatt tttaagcagg ttatcacctg tgagaatgag
     3001 ctgctcccca agactggatt ccgtagctac tgacgacgcg tcttgagtgt ctggggagct
     3061 ttcttgagaa gcctcctcag tttttagtgg tgctttcttt accctctgaa gctccttgga
     3121 aatggctttt gctgctgttt tttcttctgc taagactgtt ggtgcccgaa ataaacaagc
     3181 tagtatgata ctagagcaaa cagaagatga tagttttttt ctttgcttca tctgatacct
     3241 ccttgctttt ttaatgtttt atgaccgact ttaacagcta ctcatgtaat ctgcagccct
     3301 tgctgtgatt gcctgaaatt gaccctgagc tgccaattga ttaaattctc ctccaactcc
     3361 cagcacctga gcacctgcgg caaaccagtc tgacacattt gtgacagtta cgccacctgt
     3421 taccatgaca tcaacctgcg gcaaaggaga tttgattgcc ttaataaagg acatgccaac
     3481 tgtggcacct ggaaagacct tgaccatctc tgcacctgat tccaaggcag tcacgacctc
     3541 ctcaatagtc atacagcccg gaatataagc aatagcatat cgatgacata ggcggcttgt
     3601 ctgcctgcta aagctaggag acacaataaa ttgagcaccc gctaaaatag ctagccttgc
     3661 tgtgacatca tcaagaaccg tcccagcccc gatcaggatc tctggatcat tgccaactgc
     3721 ttcacgcagg cctgcaataa cctgactggc aaagggatta gtataggcca cctcaatggt
     3781 tttgatccca ccttcaatac ctgctaggct gcaagccatt gcttcttttt tagaagctcc
     3841 ccgaacgact aaggctaatt tattggcttt tagccttaac atgatttctg attttctcat
     3901 attaccttct tacctctcgg tttcccttca tcaccctatc aacctgacta acaggaacaa
     3961 agagctgatc atcagcaact gtacacttaa gactagctgt cgcagcagca aaatcaagcg
     4021 cagcagcaat agcctgtcct ctcatcaatt gatataagca gcctgcaaca aaggcatcac
     4081 cactgccaac tcgttgcaaa acaggcgttg atagctcaat ggagcgatgt aactgcccat
     4141 cataggcata ggctaggtaa tgattgattc cttggtcatc gatgtgacgt tccgtgtgaa
     4201 aaatggcttt taagtgatat gcctcatata aggcagccaa gcgctccttg acagcacctt
     4261 gacctgcctt agctctatca aacatggcat gatcagcttg attacacatt aagggctcca
     4321 taccaaagat caggtctgca tactgtgcaa aatgagagaa caatgtcttt gcctccctga
     4381 ctgaaatcat cgagctgcga aaattcaaat caaaggaaac acagacctgc cgcttcattg
     4441 cctcaatagc cagctgctca acaaggtcct gactgacttt tcctaaagcc aaggtaatgc
     4501 cactaaaatg aaaatgagta acttcctcaa atagtttacc ataatccaga tcttttgggc
     4561 ccaataaact aaagctagag gcagagcgat cataagcgac ctgactagga cggcagccaa
     4621 agccattttc caaataataa ataccaaccc gatcaccaca ccattgcaca tgctctgtgg
     4681 caacaccgct ttgcttcaaa aaggcctcaa cgcttcgtcc aacctgatta tcaggaaggg
     4741 cagtcagcag gctactctct gctctaaagc cactaagcgt tcttgcaata ttaacctctg
     4801 agccaccata atacagctgt gcttgacagg catgtcctaa cgtctgaaaa tgactgggac
     4861 tgatgcgaat cagcggctct cccaccaata ataccttggt cataggggta tcctttctat
     4921 agctgcagat aagacttatt gctgaaggac ttctcttagg tagtcgacaa ggtctgatgg
     4981 ctcggcatta gcaaagaaat aatgctggaa gtgctctcca gaaatggttt ccttcaagaa
     5041 atcttgatca atctccttta acacctccaa caaagaacga taagtcacag ccttcaattc
     5101 gctcaaaatt ctagcgttac gttgctctgg gatggcccgc tctttgggat agccgccccc
     5161 catcggctca gcaaataagc gctcaaacat cagggtcagg ttaagctctg ccccccaacc
     5221 aaagcccttt gcaaatggaa tagacaaggc attgccacca ttaatctgag caaaaaggta
     5281 ggcttctgtt ggctcactag caaagccaca ggtcacacct ggaaagctat ttaaggccag
     5341 catagcaccc acaccagtcc cacagcccgt tacaacaaaa tcagctgcct tacttgtcaa
     5401 taaaatagaa gctagtagcc cgttttgcac ataggtcagc tgactttcgc cctccttgcc
     5461 atacatacca tagttaaaga cctcatagcc atgcttatta gtaacagaga ctaaggtctc
     5521 gtaaataata ctgtttttag ctgcttgact gttttcatta attaatgcaa ttttcatctt
     5581 ctgtaatctc ctttgatgct tttttgtttc tttacggttg tttgccaatg taagctaaaa
     5641 tgcctccatc aacataaagg atatgcccat tgacaaagtt actcgcctca ctagccaaaa
     5701 atatagctgg accagccaga tctgctggtg ttccccaacg cgctgccgga gtcttagcaa
     5761 taataaactg atcaaagggg tgacggctgc catcagcctg acgctctctt aaaggtgctg
     5821 tctgaggcgt tgcaatatag ccaggcccaa tgccattgca ctggatattg gcttctccaa
     5881 attctgaagc gatgtttttg gttaacatct taagaccacc cttagctgcc gcataagcac
     5941 taaccgtttc acgaccaagc tcactcatca tcgaacagat attgatgatt ttcccatgcc
     6001 cttttttaat cattgatggc agaactgcct ttgaaacaat aaatggcgca ttcaggtcta
     6061 tatctaccac ctgacgaaaa tccttagccg tcatctcaag catcggtgtc cgtttaatga
     6121 tacctgcatt attcacaaga atatcaataa taccaacctc tttttcaatc tgagccacca
     6181 tctcttgaat ccctacttca tcagtgacat cacaaacata gccatgagct ttaatgccaa
     6241 actctcgata agctgctaat ccttgatcca ctaaatcctg cttgatgtca ttaaagacga
     6301 tctttgctcc agccatggca taggccttag caatctcaaa gccaatccca tacgaggctc
     6361 ccgttatcaa ggcaattttg ccctctaaag aaaagaaatg ttccattgtt ttacctctca
     6421 atctcaatat ttaagtaaac ctgtttatca aaactatagc aagactaatc cattttgtca
     6481 atcattttag taaaaacaca aaaaagagct aaagtttttc ttattgtcat tatcgaggaa
     6541 ggcttcttag ctatattttt cttgctctta ctcgctttac ttcctataag gatcccaaaa
     6601 attaggccat attgatcgct tattttgata aaataacaaa aaagtgttga caaacatttt
     6661 tgaaagcgct ataatttttc tgagtaaacc ggtaaactaa aaaggagctt attcatgatt
     6721 tctattattg ttattggtca tgggcatttt gccagtggta ttgtctcgtc tttagagtta
     6781 attgcaggca agcaagaggg cataactgct attgatttta ctgctgagat gaccgctgct
     6841 gatgtgcatg agcgcctatc agtagtctta cagtcaaaga ctcaggcact tatgctttgt
     6901 gacttattag gcggcacccc atttaaggta gcagctacct tgatggagga gctttctgag
     6961 agcacacttg atgtcctgtc tggactcaat ctagccatgc taatagaagc agtctttgct
     7021 aggcaagagc agcttgatct agaacaaatt gtcgctaagc tattaaccac agccaaggaa
     7081 gggatcagta attggaaatc cctctctggt gaggctgagg aagcagacct tgatgaagga
     7141 gggatttaat gactagacag atcaaagagg ttacccttga gcctctcata caagcagagg
     7201 tctatagcca gcagccatat ctaacaaaag ctgatattga ggcagctatt ttattagccc
     7261 ttaagcaaat ccgattaaac atggattatt ttggtactga tttccctagg ccagccacta
     7321 aggacaattg ctacccaatt atggataata ccgagtggac caatggcttt tggaccggct
     7381 gcctatggct ggcctacgaa tacactggta atgacactat caagtcacta gcacaggcaa
     7441 atgacctgtc cttcttagaa cgcgtcacca aagacattga gcttgaccat catgatttag
     7501 gatttcttta ttcaccctct tgcatggctg agtggaagct tttaaaaaca cctgaagcca
     7561 gacaggcagc cttaaaggca gcagataaat tgattgagcg ctatcaggaa aaaggcggct
     7621 ttattcaagc ctggggacaa ctcgggaaag cagaagatta ccgcttaatt attgattgtc
     7681 ttttaaatat ccagctactc ttttttgcca gtcaagaaac aggagatgac aggtatcgtc
     7741 aaatggctat caatcacttt tatgcctcag ccaacaatgt gattcgtgat gacgcctctg
     7801 cttatcatac cttctacttt gaccctgaaa caggtgatcc aatcaaagga gttacacgcc
     7861 aaggctacag tgatgactcc gcctgggcca gaggacaagc ttggggaatc tatggaattc
     7921 ccttgaccta tcgcttcttg aaggatccac agctaattgc cttatttaaa ggaatgacgc
     7981 actatttcct caatcgcttg cccaaggatc aggtatccta ttgggatttg atctttgaag
     8041 atggcagtgg tcagtctaag gacagctccg caactgctat tgctgtttgt ggtattcacg
     8101 agatgttaaa acatttacca gagaatgatc ctgacaagaa agcttatcaa gctgccatgc
     8161 actgtatgct cagatcatta attgatagct atgccaacaa ggacatcaag cctggtgctc
     8221 cacttttacg tcatggcgtt tactcttggc actctggcaa gggcgttgat gagggaaata
     8281 tctggggaga ttactactat ttagaagccc tgctgcgctt ttacaaggac tggacccctt
     8341 attggtaggc tgatagcatt tagcctacaa agactattgt taaaggagat attatgacac
     8401 caccaaacat tatcatgacc agagttgatg agcgtttgat tcatggtcaa ggccagctat
     8461 ggatcaaatt tttaaattgc aacactgtca ttgtggctaa tgatgccgtt gctgaagaca
     8521 aaatccaaca gtctctgatg aaacctgtcg ttccatcaag cattgccatg cgcttttttt
     8581 ccattcaaaa ggtgattgac gtgattcaca aagcaagccc tgctcagaca atctttattg
     8641 ttgttaagga tttagaagac atcaagcgct tggttgaagg aggggtgccc attaaagagg
     8701 tcaatcttgg aaacattcat aaaacagacg ataaaatcgc cattacccaa ttcatttcgc
     8761 taggcgacaa ggacaaggct attattcgga cattgactca cgatcatcat attgtcttta
     8821 acactaaaac aactccagct ggcaatggtg cctctgaggt taatatttta gattatattt
     8881 aagaaaggaa attgatatgg atatcaattt gttacaagca cttttaatcg gtctttggac
     8941 agccttttgt ttcagcggaa tgttacttgg tatctacacc aatcgctgta tcattctgtc
     9001 ttttggtgtc ggcattatct tgggggactt gccaacagca cttagcatgg gagctatatc
     9061 tgaattagct tatatgggat ttggtgtcgg tgctggtggt actgtgccac ccaacccaat
     9121 cggacctggt atctttggta ccttgatggc tattaccagt gctggtaaag ttactccgga
     9181 agctgcctta gctctttcga caccaattgc cgttgctatt caatttcttc aaacctttac
     9241 ctatacagct tttgctggtg ctcctgaaac agctaaaaaa cagcttcaaa aagggaatat
     9301 taaaggcttt acatttgccg ccaatggtac catctgggct tttgctgtga ttggcttagg
     9361 acttggttta ttaggcgcct tgtcaatgga tactttactt catttggttg attatatccc
     9421 acctgtcctc ctaaatggat taaccgttgc tggtaaaatg cttcctgcta tcggttttgc
     9481 tatgattcta tctgttatgg ctaaaaaaga gctgattcct tttgtcttaa ttggttatgt
     9541 ctgtgcagct tacctgcaaa ttccaaccat cggtattgcc atcataggca ttatcttcgc
     9601 cctaaatgaa tactacaaca aaccaaagca tgcaacaaca gctgaacaag gaggtcaaca
     9661 agatgactgg atctaataag ctcacaaagc gtgattatct gaaaactgct cttagagcct
     9721 ttttcctgca aaatggcttt aactatagca attatcaagg aataggctat gccaatgtcg
     9781 tttacccagc cctaaaaaag cattttggca atgacaaaac aggcctttac aaagcactag
     9841 agaacaattg tgcattttac aatacaaacc ctcatttcct accttttatc accagcctac
     9901 acctggtcat gctagaaaat aatcggcctg aagaagaaac ccgcaatatc aagatggcac
     9961 tcatgggacc tctagcaggc atcggggata cccttacgca attttgttta gcaccactct
    10021 tttcgaccat tgctgcttcc ttagcaagtg acggcctgat tttggggcca attctctttt
    10081 tcctagccat gaatattatt ctaacagcta ttaaaattgg ctctggactc tatggctaca
    10141 aggtggggac aagctttatt gataaattaa gcgaacaaat ggcaattgta tctcgcatgg
    10201 caaatattgt cggagttaca gtgattgctg gtctagctgc tacttctgtt aagatatctg
    10261 ttcccatcac atttgcagca ggcaaggtcg acgctgcaaa tgcagcccaa aaatttgtga
    10321 ccattcaggg aatgctggat aagattgcac cagctcttct gccagccctc ttcactctct
    10381 tgatgtatta cctcattaaa acgaaaaaat ggacaaccta taaattagtt attctaacag
    10441 ttattattgg tattgttggc agctggttag gggtgttagc ctagcagtct tagagattct
    10501 gttaatcagt attggagggt ctccattagc gatgagcagg tctcttttct attgggcaaa
    10561 gctaagcatt gacaccatca actctcgtag cctcagtcag gtcttttgcc ctgtagagcc
    10621 tttaagcaca agcctttact gctagctgtg atgaaggcgt cctccttcta ctggcttctg
    10681 gcacaattaa tcctttatat ctctacaagc acatgattta gcggctgatt gcgcgccaat
    10741 cttacagaag gtcgcaactt aagaaagagt aggatcattt ttgacctctt caaaggtcat
    10801 attcttggac tgaaatatta aaacaattac cattccatat gttataataa aactactaat
    10861 gatgacaaaa aggggtctat gcaatgcagc gcaaagtaac catcaatgat attgctgact
    10921 tagctaaaac ttcaaaaaca actgtttctt tctacctcaa cggtcgattt gataaaatgt
    10981 ctcaggagac aaaaagccgg atcaaggagg ctattgaagc caccaactac aagcctagca
    11041 ttgcagctcg cagtctcaat gccaaggcta ccaaattgat cggtgtggtt atcggtgaca
    11101 tcaccaatag cttttccaac cagattgtca aaggtattga aagcaaggcg caagaatttg
    11161 gttatcagat tatcatcggc aacagcaact atgatccttc acgtgaggac gaattgattg
    11221 aaaaaatgct taacctaggt gtagatggtt ttatcattca accaacctct aactttagaa
    11281 agtattcacg catcatcgaa gtgaaaaaaa agcgcatggt tttctttgac agtcagctct
    11341 atgagcatcg tacaaactgg gtcaagacca acaattatga cgctgtttat gacaccattc
    11401 agcaatgcat caccaaaggc tatcaaagct ttatcatggt tactggcaat cctaatttgc
    11461 tgagcacacg catcgagcgt gcctctggtt ttattgatgt tttagaggct aaccagctcc
    11521 agtatcgtca aatgatcatc gatgaaaacc aaaccagctc tcaagaaatt gctcagtttc
    11581 tacaaggcgc atttgataag gaacgtcaca atctggtatt tgtcccaaac tgctgggctc
    11641 tgcctaaggt ttttactgcc atgaaggcac taaaggtatc attgcccgaa actggtctag
    11701 ttggctttga taacatcgaa tggactcgct tgtcatcacc aagtattacc actattatcc
    11761 agcctgctta cgaagaaggg gagcaagcaa ccagcatttt gattgatgat atcgaagggc
    11821 atagcaagga agccaagcaa caaatttttg attgtcaggt taattggcaa gaatcaacct
    11881 tctaacagga ttttttcgcc ttctagacct taaaaaatca gccattctaa taacgatgac
    11941 aaagtaacac gaggcttaac gcttgtttgc tagcatcaga aaaaacacat aaatcagcct
    12001 gaactacccg gttgatgaaa caataaacca ttaagcaacg gtcttattcc tcataccaag
    12061 aggagcaagg ccgttttgac gtttttgaca atggtcgtta ttgtaaacgt aacggtagtg
    12121 tattactgac aggctcttca aaaaagctgt cgtccttagg tcatacgagg ccttctttta
    12181 caagcgactg ctacttcttc actactagtg tgatctttta gccaatttct gagaacatca
    12241 tcagtaaaat ctcgcacctg ccaataatgg caagcaagct tttttgacca gcaagttaat
    12301 catgtatcac ttgtgacttc aactcttaac tgtttgtcct ttcaagtcta ctataagag
//
LOCUS       DARYLD010000057        12204 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYLD010000057 DARYLD010000000
VERSION     DARYLD010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12204
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(81..1361)
                     /locus_tag="TU651_001559"
     CDS             complement(81..1361)
                     /locus_tag="TU651_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL0897535.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU651_001560"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TU651_001560"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL0897536.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTSIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPVARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TU651_001561"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TU651_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL0897537.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TU651_001562"
     CDS             6342..6845
                     /locus_tag="TU651_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL0897538.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TU651_001563"
     CDS             7344..8537
                     /locus_tag="TU651_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL0897539.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TU651_001564"
     CDS             complement(8736..9200)
                     /locus_tag="TU651_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897540.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TU651_001565"
     CDS             9468..10316
                     /locus_tag="TU651_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL0897541.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TU651_001566"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TU651_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL0897542.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TU651_001567"
     CDS             11592..12071
                     /locus_tag="TU651_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL0897543.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..>12204
                     /locus_tag="TU651_001568"
     CDS             12068..>12204
                     /locus_tag="TU651_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897544.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GA"
BASE COUNT         3668 a         2692 c         2355 g         3489 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcaa cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat gcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcgc
//
LOCUS       DARYLD010000058        12163 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYLD010000058 DARYLD010000000
VERSION     DARYLD010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12163
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(144..1283)
                     /locus_tag="TU651_001569"
     CDS             complement(144..1283)
                     /locus_tag="TU651_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0897545.1"
                     /translation="MWSEKHKSGKVNFVERYKHPYTGKWCRASVLMEKDTPRIRKEAQ
                     KYLDEKISKILTSLTTTDAYLLDVMNEWWEHHQKSLKSTSVRSLDFRIRELRNLIDPE
                     VMIAKITTKYLQSIIDKIPGSYDKRKRARQLLKQTFDYAIALEYVSINPVISTQLAKP
                     VKTIKDFEDVAQKFLEKDELKRLLDEMYRRKGSIKMAYLAEFMSLNGCRIGEALAIQP
                     DNIKNDIIEIHGTLDYTSNGYRNAIKTTPKTNSSWRETLITKREKEIIQDILKINALE
                     KNTNPNYKDMGYIFISRNGVPIQDNALNTSIRAANKRLEKPIQKELTSHIFRHTLVSR
                     LAENKVPLKTIMDRVGHADSKTTQQIYTHVTKSMKNEVVDILNRL"
     gene            complement(1411..1677)
                     /locus_tag="TU651_001570"
     CDS             complement(1411..1677)
                     /locus_tag="TU651_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HEL0897546.1"
                     /translation="MGFLDNVKEASTVSTASGENYEYVVLQVTLKEKLIGTGSGNLTE
                     LENVINKQAKKGYRLHTITTSNGGSKGFGGGDRIQATMVFEKIK"
     gene            complement(1689..2075)
                     /locus_tag="TU651_001571"
     CDS             complement(1689..2075)
                     /locus_tag="TU651_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL0897547.1"
                     /translation="MDLSLQEYVKGHGYELLFYDNRGTDKEAFVNHDCKVLGIGSYLD
                     DHEKKKAIYHEIGHKEHTNRQYELNRELCELEADRNMIHHLLKEELSYLDNVNEFNYA
                     RFMEKYKLKTITDEKMVIDEYYTLIG"
     gene            complement(2078..2428)
                     /locus_tag="TU651_001572"
     CDS             complement(2078..2428)
                     /locus_tag="TU651_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0897548.1"
                     /translation="MFPTFEKIKELCKQRGITLIQLEETLEYSRNTLYKLKTQKPNAE
                     RIAEIADYFNVSTDYLLGRTDNPAIANGTTSQKTIDFKEIAAQSMSYDGKPLTDDDID
                     LIAAVLEQRFKNRD"
     gene            2724..2969
                     /locus_tag="TU651_001573"
     CDS             2724..2969
                     /locus_tag="TU651_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897549.1"
                     /translation="MKKNIVDLQKRKEHFQWVADSLEGKENELYVERDWYDNPTLISK
                     EDAKKEVEQIRQELILLQNKSFIEYILQLLHQLFHRQ"
     gene            complement(2920..3708)
                     /locus_tag="TU651_001574"
     CDS             complement(2920..3708)
                     /locus_tag="TU651_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897550.1"
                     /translation="MSRYSDYKYANTILKSIEERPEKYLIIHYSCESFYNLGGKSPRI
                     ASISVRQFNNAQTNNFSIHQYSEILDTPITDDTYETIEKELLTDFFTFVDRNTDKNWI
                     HWNMRDTVFGFHAIEQRFKVLGGTPIIIDDDKKIDLAYLFKKMYGGGYIDNPHIEKLL
                     ELNNLTPHRFLTGKQEADAFSSRQYHELSMSTSSKVNSFSTFLTLAINDDLKTNTPKW
                     KMRGTNLSGLLSTFQETISGKVIIGIINLIVGGIVGAIIAKYIQ"
     gene            3759..3950
                     /locus_tag="TU651_001575"
     CDS             3759..3950
                     /locus_tag="TU651_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0897551.1"
                     /translation="MPDIAVGREKVVTFLKSNNIKKSDLAAAYGLNRQEVTNILSGST
                     RGPKANQFILRVIADYSIE"
     gene            4031..4342
                     /locus_tag="TU651_001576"
     CDS             4031..4342
                     /locus_tag="TU651_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEL0897552.1"
                     /translation="MPKAELVYRPAKQSEKAEAGDYEHLCQIWEGLTVGTAKVWAAEM
                     RDHPDFKQFINNPTHRIVFIDYEGFRLFVKWKSRNRYKPKKETLAEMLENIKFEKRVG
                     A"
     gene            4344..4514
                     /locus_tag="TU651_001577"
     CDS             4344..4514
                     /locus_tag="TU651_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897553.1"
                     /translation="MNKLELFLLVTTVALAIVARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            4507..4710
                     /locus_tag="TU651_001578"
     CDS             4507..4710
                     /locus_tag="TU651_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897554.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            4707..5093
                     /locus_tag="TU651_001579"
     CDS             4707..5093
                     /locus_tag="TU651_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897555.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELLTLNDVERYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDKR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            5237..5440
                     /locus_tag="TU651_001580"
     CDS             5237..5440
                     /locus_tag="TU651_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897556.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            5528..5827
                     /locus_tag="TU651_001581"
     CDS             5528..5827
                     /locus_tag="TU651_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897557.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            5827..6984
                     /locus_tag="TU651_001582"
     CDS             5827..6984
                     /locus_tag="TU651_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL0897558.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKAFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGTLEKLIGKTTFADLLAEVIDKPQGKPVLVKNSDKRPALNSLEQAIKDFE"
     gene            6993..7556
                     /locus_tag="TU651_001583"
     CDS             6993..7556
                     /locus_tag="TU651_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL0897559.1"
                     /translation="MIMTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            7599..9521
                     /locus_tag="TU651_001584"
                     /pseudo
     CDS             7599..9521
                     /locus_tag="TU651_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
     gene            9526..11910
                     /locus_tag="TU651_001585"
     CDS             9526..11910
                     /locus_tag="TU651_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL0897560.1"
                     /translation="MKQEKLIVKSSPLQELHIATGNSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWRDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTEGS
                     TANGLVIYDEVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDITPTNKLPSSK
                     AMNAFVSDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETVVAIKAQA
                     FSSEVFTESDLNKIVLANGVYDLRDNSFKTKFDPELHARSSHPVVYDPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYAIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRKALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLAKNAFNHRLRELSYENKNVKSGGKQAKNWVGFKLKSEF"
BASE COUNT         3827 a         2123 c         2671 g         3542 t
ORIGIN      
        1 cttattatat ctaattcatt gcttgattga tctttatata aatcaataag tgattaaata
       61 aaacattaaa aaaccttgtc atatcaacgt ttgttgaaga tgtcaaggtt ttttcttgtg
      121 ttttggggca tttttggggc atattatagc cgatttaaga tgtcgacgac ttcatttttc
      181 atgcttttcg tgacgtgggt atagatttgt tgagtagttt tcgagtcagc atgtccaact
      241 ctatccatga tagtttttaa gggcactttg ttttctgcaa ggcgactcac cagggtatga
      301 cggaagatgt ggctggtgag ttctttttga atcggttttt ctagtctctt atttgccgct
      361 ctgatagagg tgttgagggc gttgtcttga ataggaacac catttctgga aatgaagatg
      421 tagcccatgt ccttgtaatt aggattagta tttttttcaa gagcattaat tttcagtata
      481 tcctgaataa tttctttttc acgtttggtt atcaatgttt cacgccaact ggaatttgtt
      541 ttaggggtgg ttttgatagc gtttctatag ccatttgagg tgtagtcaag agttccgtgg
      601 atttcaatga tatcattttt gatattgtct ggctgtatag ctagagcttc tccaatgcgg
      661 cagccattta agctcataaa ttctgccaga taagccattt taatcgatcc tttacgtcta
      721 tacatttcat ctaatagcct tttgagttca tctttttcta aaaacttctg ggcaacgtct
      781 tcaaagtctt tgatggtctt aacaggtttt gcgagttggg tactaataac tggattgatt
      841 gagacatact ctaaagcgat agcgtagtcg aaggtttgtt tgagcagctg ccgtgctcgt
      901 ttacgtttgt cataactacc tggtattttg tcgataatac tttgcaggta tttcgtggtt
      961 atcttggcaa tcatcacttc tggatcaatt aagtttcgca attctcttat tctaaaatca
     1021 agagagcgga cagaagttga tttgagtgat ttctgatgat gttcccacca ttcgttcatg
     1081 acatctagta ggtaggcatc ggttgtggta agacttgtta agattttaga tattttttcg
     1141 tcaagatatt tttgggcttc ttttcgtatt cgtggcgtgt ctttttccat aaggacagaa
     1201 gctctgcacc acttgccagt atacgggtgt ttgtaccgtt ctacaaaatt tacttttccg
     1261 cttttgtgtt tttctgacca cattgttttt tacctcattt tctgttaaaa taggtatagt
     1321 aaagagacct actgcgaagc aggtttttac tatactagat ttgcctcacg ctcgcaccga
     1381 ccaaaatttg agcgtagggc tttttttatt ttacttgatt ttctcaaata ccattgtagc
     1441 ttgtattcta tctccgccac caaatccttt actgccacca tttgatgtgg taatagtgtg
     1501 taggcgatat cctttttttg cttgcttatt aataacattt tcaagttcag ttaaatttcc
     1561 tgagcctgtt cctataagct tttcttttag tgtaacttgt agcacaacat attcataatt
     1621 ttcgccagaa gcagtcgaaa cagtactagc ttcttttaca ttgtccaaaa atcccatgat
     1681 aatctccttt aacctattaa agtataatat tcatcaatta ccattttttc atcggtaatt
     1741 gtttttaact tatatttttc catgaaacga gcatagttga attcatttac attgtctaaa
     1801 taagataact cttcttttag caagtgatga atcatatttc tgtctgcttc taattcacac
     1861 agttctctat ttagttcata ctgtctgttg gtatgctctt tatgaccgat ttcatgatat
     1921 attgctttct ttttttcatg atcatcaaga taagaaccaa taccaagaac tttgcagtca
     1981 tggttaacaa acgcttcttt atctgtgcca cggttatcat aaaataaaag ctcataaccg
     2041 tgacctttga catactcttg aagtgataag tccatagtta atctctattc ttgaatcttt
     2101 gttctaagac tgctgcaatg agatcaatat catcatcggt aagtggtttt ccatcataag
     2161 acattgactg agcagctatc tctttaaagt ctattgtttt ttgactagtg gtgccattag
     2221 caatagcagg attatcagtg cgaccaagca aataatctgt tgaaacattg aagtagtctg
     2281 ctatttcagc aattctttca gcgttgggtt tttgagtttt caacttatag agtgtatttc
     2341 ggctatattc taaagtttcc tctagttgaa taagtgtaat tccacgctgt ttgcacaatt
     2401 ctttgatttt ttcaaacgtc ggaaacattg atttatcaac ctttctaagg catgacaaaa
     2461 aatatttcaa ctttttgggt gaaaaatgtt gacaattcaa ccaaatgggt gtatcatatt
     2521 ttttgtaagc aagagataac taaaaaaaca actaagcaaa caactataaa acagttttgg
     2581 cgaacgagtt taagttgatt tgttaaggtt ctttaatatg ctttaattct aactttttag
     2641 gtgtgagttg tcaagtggtc atatactaaa aagttgaaaa tttagttatt tcttgtttac
     2701 aaattttaaa acaaggagga aaaatgaaaa aaaacatcgt tgatctacaa aagcgtaaag
     2761 agcattttca gtgggtcgct gatagcttag aggggaaaga aaacgaactt tacgtggaaa
     2821 gagattggta cgacaatccg actcttattt ccaaagagga tgcaaaaaaa gaagtagagc
     2881 aaatacgaca agaacttatt ctacttcaaa ataaatcatt tattgaatat attttgcaat
     2941 tattgcacca actattccac cgacaataag gttgattata ccgattatca cttttcctga
     3001 gattgtttct tgaaaagtgg aaagtaatcc agataggtta gttcctctca ttttccattt
     3061 aggggtgtta gtttttaaat catcgttgat agctaaagtg aggaatgttg aaaagctatt
     3121 gaccttgctt gatgttgaca tacttagttc atggtattgt ctcgaagaga aagcgtcagc
     3181 ttcttgttta cctgtcagaa aacgatgtgg ggttagattg ttcaattcaa gtaatttttc
     3241 aatatgcgga ttgtcaatat atcctccacc gtacatcttt ttaaacagat aggctaaatc
     3301 gatctttttg tcatcatcaa tgattattgg tgtgccgcct agaactttga atcgctgctc
     3361 aatagcatga aagccaaaga cagtatctct catattccag tgaatccaat ttttgtcggt
     3421 atttctgtca acaaatgtga agaaatctgt taacagctct ttttcgatag tttcataagt
     3481 atcatcagta attggggtat ctaatatctc ggagtactga tgaatggaaa agttgttggt
     3541 ttgggcatta ttgaattgac gaactgaaat ggaagctatt ctaggacttt taccacctag
     3601 attataaaaa ctttcgcagg agtaatggat aatcagatat ttttctggtc gttcttcaat
     3661 acttttaagg atagtattag cgtatttata atcagagtat cgagacattt ttacctcaag
     3721 tttttatttt tattatatca gaaaagaaag gagaaaatat gccagatatt gcagttggac
     3781 gagaaaaagt tgttaccttc ctaaaaagta acaatatcaa gaagagtgat ttagcagcag
     3841 cctatggtct caatcgtcaa gaggtcacta acattcttag tggctcaact agaggaccaa
     3901 aggctaacca gtttattctg cgagtgattg cagattacag cattgagtaa atgcaaaaaa
     3961 aaggaactga ttgcagtcag ccccttatca aaaattctac ttacattata tcacagattg
     4021 gaggtaagaa atgccaaaag ctgaattagt ttacagacca gctaagcaat ctgaaaaagc
     4081 agaagctggt gactatgaac acctttgcca aatctgggaa ggtttaacag tcggaacggc
     4141 caaggtttgg gcggcagaaa tgagagatca cccagatttt aaacaattta tcaataatcc
     4201 aacgcataga attgtattca ttgattacga aggtttccgt ttatttgtta aatggaaaag
     4261 tcgtaaccgc tataaaccca agaaggaaac cctggcagaa atgcttgaaa atattaaatt
     4321 cgaaaaaaga gtaggagcat aacatgaaca aattagaatt atttttatta gtaacaactg
     4381 ttgctttagc aattgttgcc aggatacaat atgaagtcat caaaaaacac aactcgccag
     4441 agaataagcg aaaaattttt agggaagtag ctttagaaaa cagcaagaaa tggagtgcag
     4501 aacgttatgt ctaaatggga attacaaaaa caactactgg aaaatgcgac agattttgag
     4561 agcacagttg aggctttact tgacttaaac gagtctggcg aaatatctga tctggaactc
     4621 ttactgaact taaaggataa attcagaagc tattccaaag aaaaaatacg tatccttaat
     4681 gaaattctca agctaggagg tgcagaatga tgacaacttt tgaaaagatt attaagaaaa
     4741 ttaatcggat tgagggggag ttagttaaac ctgaagctga aagacgagat agcttaccta
     4801 tcctatctgc tcagttgggt tctattaaac aagatttaaa attgatgctt tggattgagc
     4861 tactgacgtt aaatgacgta gagagatatg aagctcttta tcaaggaaat gattttaaat
     4921 tcagtgaaac tttcttagag cgtcaagcga cgagaaaagc cttttggaga cgattagcta
     4981 aagaaacttt caaagaagac caggataaga ggaactttgt taagttggct gagaaagaat
     5041 ttaaaggtgc aactttgtca tggcaagaat ttttgtgggg taaaaagaaa tgaatatatc
     5101 actaaaattt attgatgaaa ccctagctgg cttaaatgat attttacgtc agggggggct
     5161 cttgctccca aaaccaagcc ttagcagacg cagtttttat actaacagct ttaaaacaag
     5221 taattgagga gagaaaatga actatttaga atacgcacta gtttatcttg aacgtgagtt
     5281 agaaattatt gataacgaag ttatcgaagt tgagttgccg ggcggagatt gggagtttgt
     5341 gcctaatccc tactacgaga aaggtctaca tgatagccca cactatcgta gtcaggttgc
     5401 taaagacatt cttgatatta aaggactttt ggggaggtga ggctattgat tgcatcaaaa
     5461 aagacggctt aggaaaccgt caacaattat acacaattaa attataacac agaaagagag
     5521 aaacacaatg attgaagtaa cttttaaagc agagagcatg gcaggtgttt tcgatgctat
     5581 gcgtgaagct ctggatatgc cgaagacagt aaccaaggat gttgttgaag aaaaaccagc
     5641 tcctaaaaag aaagaagagt ctgtaacttt gacattagct gatattaaga aaatggctaa
     5701 agccaaggtt gaagaaggga agtcaaagga catcaaggaa gtcttgaaag agatgaacgt
     5761 cgcaaaagtt ggtgaacttg aagaatacca gtttgctgag tttgttgaga agttggaggc
     5821 cctctaatgc cagtagaaaa tcacgcacta ctgtctgctt ctagtgctca cagatggctt
     5881 tattgcccta tgctgccgag attagaagca gactatccta gccgcgatac cgtatacact
     5941 caagagggca caagcgccca tgagctttct gaaatcaaac tgatgtacaa gtctggtaaa
     6001 atcaccaagc gtaaatttaa cacgttaacc aaggctttta aggaaaactc agacttctac
     6061 aacgaagaga tggaagagat gacggaactt tacacagata ttgttatgga gcacctaaat
     6121 gcttatgaga acgccgaaat tgaacttgaa aaacgggttg attttagcga ctgggtgcct
     6181 ggcggttttg ggacttcgga tgttgtcatt ttagcggatg gggtcattga aattattgat
     6241 cttaagtatg gcaagggcat gcctgtgtct gctaaccaaa acccacagat ggggctgtac
     6301 gctctaggag cttatgcttc ctacgatatg gtttatgact ttgaccgtat caaaatgacc
     6361 attattcagc cacgtttaga ttcggttagt tctgttgaca tttacgtgga ggagttactc
     6421 tactgggcgg ataatgttgt cttgcctatg gccgctcaag cagacgcagg cattggtgac
     6481 tggaacctaa gtgaaaaagt attgcagtgg tctcctgtcg cagctaaatt ggtaccaaga
     6541 gcgcaagaaa attgggaatt aattgataaa tatgactatc aggagcctgt ctatttatct
     6601 gatgaagccg tcgcagagat tcttgacaaa gcctcagcta tcaagaagtg ggttgagtca
     6661 gttgaagcct atgccctgaa agaagcactc tcgggaaaag aagttccagg ctataagatt
     6721 gttgaaggta gaagtaatcg agtcatcact gataaagaca aagcaattga tattttacaa
     6781 gataacggct ttgacgatga gatttttaaa ccgaaagagc tgttagcaat gggaactctt
     6841 gaaaagttaa taggtaaaac cacttttgct gatttattag cagaagtaat tgataaacca
     6901 cagggcaaac ctgtccttgt taaaaatagc gacaagcgac ccgcattaaa tagcttagaa
     6961 caagcaatta aagattttga ataggagaaa ttataattat gacaccaaac acaactaaag
     7021 tagtaaccgg aaaagtacgc ctaagctatg tagctttact agagcctaaa gcctttgaag
     7081 gtcaagaggc taagtattca acagttatct taattccaaa aacagacaaa gtcacaatca
     7141 agaaaattaa agacgcgcag aaagctgctt atgaggctgc caaggacaat aaactcaaag
     7201 gggttaaatg ggagcgcgtt aagacaacgc ttcgtgacgg cgacgaagaa atggataccg
     7261 aagagcaccc agagtacgct ggacacgtgt tcatgtcagt gtcaagtaaa actaagccac
     7321 aaatcattga caagtataaa aaccccgttg actcagcgga tgaagtttac tctggcgtct
     7381 atgctcgcgt atcacttaat gcctatgctt acaacacagc gggaaataaa ggaatctctt
     7441 gcggattaaa caacgtccaa attgttgcta aaggagacta ccttggcggc cgttcgtcag
     7501 ctgatgcaga ttttgacgag tggaacgaag aagaggacga agacgacatt ttatagtaga
     7561 gggcctcttt agaggctcct catttttaaa ggagaggtat gagacattta aatattgata
     7621 ttgaaaccta tagttcgaat gacatcaaaa atggggttta caagtacgct gacgcagaag
     7681 attttgagat tttacttttc gcttactcta tagatggcgg agaagtagag tgccttgatt
     7741 tgacaaggca gtctctacct gaagacatca aagatatgtt atttgatgat aaagtccgaa
     7801 agcacgcctt taatgcccaa ttcgaaagag tttgtctcag tcgttacctc ggtctacctt
     7861 actatctaga tccttgccaa tggcaatgca ccatggtgct ggcccaagag ttggggctgc
     7921 cttcaagctt ggaaaagtgt gcgctgtatt taaaattagt gcaggaaaaa gatacctcgg
     7981 gtaaaaactt aatcagatac ttttccctgc cttgcaaacc aagtaaagct aacggtggga
     8041 gaactagaaa tttaccagaa cacgcccccg aaaagtggta aatgtttatt gactactgca
     8101 tccaagacgt tgttgttgag atggcaattg ccgaaaaact agagtcagtt cctgtgcacg
     8161 accgtgaatg ggactactac gcatgcgacc agagaatcaa cgacagaggc gtggcgcttg
     8221 ataaagagtt agttgcttcg gccttgtatt gcaaagatgt taagatggaa agtttgtctg
     8281 gtgaactaaa agctctaaca ggacttgata atcctaatag cagggcgcag ttgttaccgt
     8341 ggctaaaaga acacggttat tcggttaatg gtctgactaa agcggatgtt gagcaggagc
     8401 ttaagacggc cgaaggagaa cttaagagag ttttagaact taaactacaa accgctatgt
     8461 caagtctaaa aaaatatgaa gctatggaaa gagctatgtg ctcagacgga cgagttcatg
     8521 gactacttca gttttacgga gctagcagga caggaagatg ggcgggcaga gttgtccaag
     8581 tacagaactt agctaggaat tatataaagg atctagatga tgctagagag tatgttaaaa
     8641 agcgtgatat tgatgctgtg gagattttat acgatagtct taacgacact ttaaagcagc
     8701 tagtaagaac ggcactcgtg gccaaagact gctgtacctt ctacgtctct gacttctcag
     8761 cgattgaggc tagggtgatt gcgtggtttg ccggagagca gtggaggctt gacgtgtttt
     8821 cgacgcacgg aaaaatctat gaggcatccg ctagccagat gttcggaatt ccaattgagg
     8881 agattgataa ggaactacgc caaaaaggca aaatctcaga gttggcactt ggctatcaag
     8941 gaggtcctgg agcgctcaag cagatgggag ctctaaatat gggagtcaag gaagaggagc
     9001 tccaagggct agttgatgac tggcgcaggg ccaataagaa aatcgtccaa ttttggaaag
     9061 atgtgcagag agccgccatc aaagctatca aatcgagagc accaataaaa cttggaaaac
     9121 tacgatttag ataccgtaaa ggtttcctct ttataacatt gcctagcggt aggaacttag
     9181 cttatgcaag agccaaggtt gagccaggcg actatggaga caaaatcgtc tatgagggcc
     9241 aaggagataa ggcctacttc acagcgcaag agacttacgg cggtaagctt gtcgaaaata
     9301 tcgttcaggc gacggccagg gatattctag ctgaagcgct tctgaggatt gaagctgcag
     9361 gctatggtgt tgttttccac gttcatgatg aggctattat cgaaggctca ggcctgacaa
     9421 tcgaagaagt taatgatttg atggctcagg ctcctgaatg ggcggagggt cttcctttaa
     9481 atagcgaagg ctacgtaaca aagtattata tgaaggatta gatagatgaa gcaagaaaaa
     9541 ctaatagtaa agtcttctcc tctgcaagag cttcatatcg caacgggtaa ttcacgaaca
     9601 gctaagacgt ggaaaaatat tacgctaact tggcaggagc tggttgagag gttagagaaa
     9661 cctacagtca cccaagagac gtttgcggag taccagaaga tgtctcgagc agaaaaaggg
     9721 caagcaaaag acgtaggagg ttttgtcggc gggtggctaa agcagggtaa acggaaaaac
     9781 gaaaatgttc aaagtaggtc cttggttgcg cttgacgcag atagcccaag taaagatttc
     9841 ttagataggc tagacctgct tgcagactat gcatacgtac tctacagtac tcacagccac
     9901 tcaaaaaaag ctgctaagta ccgtcttatt atccctactg accgtttaat gatgcctgat
     9961 gaatatgagc cagtcgctag gtacttggct aatcaactag gcatgtcgaa ctttgatgac
    10021 acgacttatc aaagtgtgcg tttgatgttc tggccgagcc actcgagaga tgctgacttt
    10081 acgtttaaat ataacgatga ggcttttcta agtgttgatg aggtgcttga tacatacccg
    10141 gactggcgtg actcaagctt ctggccagaa agcccgacgc acgctgttaa aagacagcgt
    10201 gaagctaaaa aacaaggtga cccacttagt aaaaaagggc ttattggagc cttttgtcgt
    10261 aactatgaca ttagacaggc cattgcaacg ttcttgcccg aggtttatga agaaggaacg
    10321 actcctgata ggtacaccta cactgagggt tcaaccgcaa atggcttagt catctatgat
    10381 gaagtcttcg cttatagcca tcacgggaca gatcccgtgg gggatacgct tgtaaatgca
    10441 tacgaccttg ttcgtatcca taaattcgga gagcaagata gcgaggctaa agatattact
    10501 cctactaata agttgccatc aagtaaagcg atgaatgctt ttgtctctga cttacccgaa
    10561 attaaagact atttaatggc ggaggcttta ggcgattttg atgaagagtt accagtcgaa
    10621 gatgacagaa gctggcttga aattgatgag aggggcgaac ctgaggtcaa tagttatttg
    10681 ctagcaacgc agattattaa ggaggttccg atttattggg acggcttaga atttttacgc
    10741 tacgacgcta aaaaaggcat ctggttgcca aacgcagagg agtatttgaa gagttatatc
    10801 tcaactaaga aactcggtaa aattactaag attaggcaca ttagcgaaac cgtcgtagcg
    10861 attaaggcac aggctttctc aagcgaagtg tttactgaga gcgatcttaa caagatagtg
    10921 ctagcgaacg gagtctatga cttgagggat aacagtttta agactaagtt tgatccagaa
    10981 ttgcatgcaa ggtcaagcca tcccgttgtc tatgaccccg aggcggcctg tgaaaccttt
    11041 gagggttttc ttagggagac cgtcggagct gaaaatatag atttcatctt tgagtggttc
    11101 ggctataact tttatcgcga atatgctatc caaaaaatgc tattcatcta cggcagcggc
    11161 ggtactggta aatcaacact gattaatatt ttacgtgaaa tgataggtgc tgataattac
    11221 tcagccgtga cactgcagta cctgatgcaa gaacgctttg caaaaatcgg cttatatcga
    11281 aagactgcta acttcgatac cgatgctaaa cctcaatact tagcagatgg cgcaacactt
    11341 aaaatgttga cgggggagga tactattcac gcagaccgta agaataaaga gccgattaac
    11401 ttttacaatt atgctaagct gtcttttgcc atgaatgagc tcccacctat gcgagatttc
    11461 agcggaggac ttaaacgccg catgatgatc ctcgagatgg ataaggtttt aacgcaggaa
    11521 gttaaggcga aatacccgct agataagatt atgagcgagg tgccaggtat ctttaatagg
    11581 gcgatggagg ggcttagaaa ggccttaagt aagagagatt tcagtattag tgccagcatg
    11641 agatcaagtg tcgagaaatg ggaaaaaggc aacgatgtcg tggccatgtt ccttgaagac
    11701 gagtgtgaac ttggtgaaga cttcaaagtt cctgttaggg atgtctaccc agcctacaag
    11761 ttctattgtc aggattcagg ctacaaacct ttggcaaaaa atgcatttaa ccaccgacta
    11821 agagagttaa gttatgaaaa taaaaacgtt aaatctggag gaaagcaagc caaaaattgg
    11881 gtcggtttta agttaaaaag tgagttttag gggttacttt tttgggatta gagtttggta
    11941 accctagaaa aaagttacca agttaccggt ttttcaaact ttaaaaataa aaaatttaaa
    12001 aataattttt aaaaaatcaa aactgaattg gaaaaatcgg taacttagta actcgaccct
    12061 tagaaatggg ctcgaaaagt agccctggta gcttattggt agccctaaga aacctttcat
    12121 agcaatagct tagcccctat ggttaccaat ctaccacttt tct
//
LOCUS       DARYLD010000059        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYLD010000059 DARYLD010000000
VERSION     DARYLD010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(152..433)
                     /locus_tag="TU651_001586"
     CDS             complement(152..433)
                     /locus_tag="TU651_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL0897561.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TU651_001587"
     CDS             complement(466..1233)
                     /locus_tag="TU651_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL0897562.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TU651_001588"
     CDS             1352..2092
                     /locus_tag="TU651_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL0897563.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TU651_001589"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TU651_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TU651_001590"
     CDS             3072..5315
                     /locus_tag="TU651_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL0897564.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TU651_001591"
     CDS             5428..6489
                     /locus_tag="TU651_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL0897565.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TU651_001592"
     CDS             6567..7172
                     /locus_tag="TU651_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL0897566.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TU651_001593"
     CDS             complement(7423..8637)
                     /locus_tag="TU651_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0897567.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU651_001594"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TU651_001594"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL0897568.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TU651_001595"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TU651_001595"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL0897569.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     DNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TU651_001596"
     CDS             10819..11535
                     /locus_tag="TU651_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0897570.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TU651_001597"
     CDS             11627..>12157
                     /locus_tag="TU651_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL0897571.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3304 a         2348 c         2831 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacgata atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYLD010000060        12117 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYLD010000060 DARYLD010000000
VERSION     DARYLD010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12117
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..488
                     /locus_tag="TU651_001598"
     CDS             <1..488
                     /locus_tag="TU651_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0897572.1"
                     /translation="SGKKIKSISEALDISYPTLSSYNQGIRKPKKENAQKLADYFGVS
                     VAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIELGEIHLSMPLN
                     EVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTEEFQIRRADRDR
                     K"
     gene            542..1633
                     /locus_tag="TU651_001599"
                     /pseudo
     CDS             542..1633
                     /locus_tag="TU651_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(1748..2140)
                     /gene="rpsI"
                     /locus_tag="TU651_001600"
     CDS             complement(1748..2140)
                     /gene="rpsI"
                     /locus_tag="TU651_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL0897573.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(2160..2606)
                     /gene="rplM"
                     /locus_tag="TU651_001601"
     CDS             complement(2160..2606)
                     /gene="rplM"
                     /locus_tag="TU651_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL0897574.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            complement(3145..4005)
                     /locus_tag="TU651_001602"
     CDS             complement(3145..4005)
                     /locus_tag="TU651_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL0897575.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            complement(4189..4707)
                     /locus_tag="TU651_001603"
     CDS             complement(4189..4707)
                     /locus_tag="TU651_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL0897576.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            complement(4708..5454)
                     /gene="rlmB"
                     /locus_tag="TU651_001604"
     CDS             complement(4708..5454)
                     /gene="rlmB"
                     /locus_tag="TU651_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL0897577.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            complement(5503..6291)
                     /locus_tag="TU651_001605"
     CDS             complement(5503..6291)
                     /locus_tag="TU651_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897578.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            complement(6508..6915)
                     /locus_tag="TU651_001606"
     CDS             complement(6508..6915)
                     /locus_tag="TU651_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL0897579.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            complement(6908..8251)
                     /locus_tag="TU651_001607"
     CDS             complement(6908..8251)
                     /locus_tag="TU651_001607"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL0897580.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            complement(8369..8905)
                     /gene="cysE"
                     /locus_tag="TU651_001608"
     CDS             complement(8369..8905)
                     /gene="cysE"
                     /locus_tag="TU651_001608"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL0897581.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            complement(8917..9669)
                     /locus_tag="TU651_001609"
     CDS             complement(8917..9669)
                     /locus_tag="TU651_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL0897582.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            complement(9662..11806)
                     /gene="pnp"
                     /locus_tag="TU651_001610"
     CDS             complement(9662..11806)
                     /gene="pnp"
                     /locus_tag="TU651_001610"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL0897583.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
BASE COUNT         3507 a         2827 c         2316 g         3467 t
ORIGIN      
        1 aaagtggcaa aaaaataaaa agtatcagtg aagcgctaga tatatcctac ccaacactat
       61 ctagctataa ccaaggaata cgaaaaccta aaaaagagaa tgctcaaaag ttagcggatt
      121 attttggtgt ctcagtggca tacatccttg gaattgacga agaaaagtac gctccgtcaa
      181 atttaaaaat cgtcactgat agtttcaaga catctgaaat tacttctgta acacctttta
      241 aaagcgatat ggagaagctt aagaaaggaa tcgaactagg agagattcat ttgtctatgc
      301 ccttaaacga ggttttctca gatgacttta gacgtattct ttctaactac ttaatggatt
      361 atgaagaaac ctttatcaaa gacttaatta agtttatgaa taaccaaggc caaaaatcgg
      421 atatttggaa aacatggata caaaccgaag agtttcaaat tagacgagca gatcgtgaca
      481 gaaaatagac taatatttct caattacata agctccgaaa acttagaaac ggagaactgt
      541 tatgtctgta cacaaatacc aatctacaaa aggaattacc tattttgtta aagtttacct
      601 tggtctaaac gactacggta agaaaaaata ttacactaaa cgaggattca agacgcgtaa
      661 agctgccaaa gctcatgaaa ctgctgttaa tcatcagctg aatagtggaa cttttgccca
      721 tcttactgct caaacaacct atacttacca agaactatat caaaggtggt atgaagctta
      781 caaagatacc gttgaaacaa ctactgcagc taaaacggcc gatttatatc gccttcatat
      841 tcttccaacc tttggagaga aaaagatttc aaaaatcagt ccgctagact gccaaacctt
      901 tatcacagat aaagcgaaat cattcaagaa catgaagcaa atcaagtcat acacctctaa
      961 aacctttgaa tttgccatca atatgaatca tattgaacgt aatcctatga gcaaagttat
     1021 tatgcctaaa ctcaaaaaaa ctgtcagtga gaactactgg acagttaacg agttgcatca
     1081 ttttttgaca atcattttag aaaatgaacc ttataaacat tatgctctat ttcgattact
     1141 agcatacagc gggttacgaa aaggagagct ctacgccctc aaatgggaag attttgattc
     1201 tgagaatcaa ctattaacag tcagcaaaag tttaggaaga atagatggtc atgccattga
     1261 aaaaggaact aaaaatacat tctcagtacg ctctatctat cttgatgatg aaacctgttc
     1321 tatcctcaac aaatggaaac aggaaactag caaagaaaag gggcaattat cagtacagcc
     1381 cctttctctc gacaaagaat ttatgtttac atactgcaac agagatggtg agatagaacc
     1441 cttacacgct gactatatca acaatattct aaaacgcatt atacgaaagc ataatcttaa
     1501 aaagattagc ccacatgggt ttaggcacac tcacgcaacc ttgatgattg aaatgggaat
     1561 tgacccagtt aataccgcta agcgtctagg tcatgctagc agccagatga ctttagatac
     1621 ttatagtcat tctaacttaa cctctcttaa aactaggtct caacagatta ccaaggtgct
     1681 tttttcaaca aaaaagcacc ttgcgaaaac ttcgcaaagt gctctgaaac gttggtataa
     1741 ctggatatta acgttttgag aactggctag ctttacgggc ttttttaaga cctggttttt
     1801 tacgttcaac catacgtgcg tcacgtgtaa gaagaccagc gcgctttagt gagtcacgga
     1861 aatctgggtc cacttgaaga agcgcacgag cgataccatg acgaatcgca cctgattgac
     1921 cagcataacc accacctaca acgttaacaa aaacgtcgta tgagccttca gttgaagtca
     1981 ctgcaaaagg ctgattaatg actaaacgta ggtcagcatg tgggatgtat tcttcaacat
     2041 cttttttatt aacagtgatt ttaccagtac ctggaactaa acgaacgcgt gcaacagcgt
     2101 ttttacgacg accagtacct gcatattgtg cttgtgccat tatttaatgc tcctttctct
     2161 tagataagtc ctgaaatatc aagtacttct ggttgttgtg cagcatgagt gtgctcaccg
     2221 ccaacaaaga cctttaattt cataccttgt gcacgtccaa gagtgttgtg tggaagcatg
     2281 ccttttactg acttttcaat caaacgaacg gcatttttag agcgaagctc accagcagtg
     2341 attgatttca agccacctgg gtacattgag tgagtgtaat aaaccttatc agttgctttt
     2401 ttaccagtta atttaacctt ctcagcattg ataacaataa caaagtcacc tgtatcagtg
     2461 tgcggtgtga aagttggctt gttctttccg cgaagtacgc tagcaactac tgcagaaagg
     2521 cgtccaagtg gcacatctgt tgcgtcaaca acgtaccatt tgcgttcaac ttggcctggt
     2581 ttagccatga aagttgtttt gttcatgatt tctcctatac gaattcgttt ttgtttacat
     2641 tagtgatgga tgttccggtc catcgaaggt atttggaagg ttccggggcc tttcaaatgg
     2701 ggtaaacaat accgtctact atagtatcaa acttcttaac tgatagtcaa gtggtttagc
     2761 tctatttctt tgattatttt tgctttttca caagaagaac aggcttgctt ttgagctgga
     2821 ctattagcct tgacttccct ccaaaaaatc cgctcagttc ctgttagctc ctatgcaaat
     2881 aacaatacaa agattagtgg tggaatgacc aaagctcctg tcaactgcta aaacatttga
     2941 catctgactt ctggcaaatc aaaaagccct gttctgttat gctagttcct tacctgcacg
     3001 cgcaccttca ttgtcaaaca attcattcta acttttgatt aaaaataaaa aatgcgaaca
     3061 cccatactct taagcggcat cacagctaaa acaagctata gtcgacaaaa aagaattgaa
     3121 acaagcgctt caatcctttt ctttttatct tttttccttg ccgatgacaa agaccgctaa
     3181 ggtatctgga cctgtatgag cagcaatcac cggtccgagc ggcagcataa agacatcact
     3241 gataccttca tgtgctaata gctgttctcg taggtcatct gccccagtct gatcactagt
     3301 ataggacaca acaacagttg aatcagcaat atcttttgtg gctctgtcag caatttcctt
     3361 aatggccttt ttacggccac gaatcttggc aataggaact aattttccgc tggcatcaat
     3421 ccataagaga ggcttaatat tcactaggct gcctataaaa gcagagcctt ttgacaagcg
     3481 tcctcctcgc acaagatgaa aaagatcatc tactaagaaa taggtgcgta agcgaggcaa
     3541 aataccttct attatcgctt tggtttctaa taggcttttt ccattatcac gcgcctccga
     3601 ggctagcatg gtcaaatagc cctctcctcc tgctgcagcc aagctatcaa caatctcaat
     3661 tacagcgtcc ggatagtcct ccaaaaccag ctcacgtgcc atgacagcac tttgataggt
     3721 acctgatagg actgaagaaa aggcgatata taaaagagct tggttatcag ctgcgtaatg
     3781 tcgaaaaatc tcttcaaact gaccaacatt tatctggctt gttttgggct ggctcccact
     3841 tttcatcata gctagcaaag catcactcgt taatctatct ggaccaaccg tcttgtaaac
     3901 cttgccatca cattcaacag ttaggcctac tatatcgatg ttatgctcct ttgcccaaaa
     3961 agaatctaaa tccgctgttg aatctgtcat caatacaaat gtcatctgaa ctcccaagta
     4021 acgtcattat cgtttaataa tcaaatgatt ttctcatagt ataacaaaaa aatatcagct
     4081 aagaaagcaa taagaaccag ctgcctcaga aatgatcacc gttagatcgt atgagctgct
     4141 ctagcagcct ggagaatcat acctagaaaa gctagcaaga taagcttatt aatcatctaa
     4201 tcgattcata aagtccttga gctgattaag ctgcccttga tcaaagggac ccagtctagg
     4261 ctttttaaga tcaatatcct gtgacagctt atctaaatcc gacttaacag cattaacacg
     4321 ctgctcaagc tctttagcag tgacacgcaa ggcgccttgg gaaaagatcg tccactgttc
     4381 attcagatca ctagtagcca cctctaccat ggttagagcg gtgtttagct cagcagcagt
     4441 ccgctcaata tagctatcag ctgtttcttc ctcttcggta aaaataacag aaatcctata
     4501 ttggtcataa cgctgtctaa gtcctggaac atactgagca tcaaatacgc aaataatgtc
     4561 actatcatca aaatgcgcat agttgttcag cttatttagc aagatccttc tagcttgatc
     4621 caattggttt gtcttaaaaa actgacgagt tgattcccaa aaggcaatca tgttatagcc
     4681 atcaaccagc aatagtcttt ttttcatcta taatttattt ctaaatactt catacatcaa
     4741 aatagcagct gcaacgctag catttaagct ctgaacatga cccatcatag gaatggtaat
     4801 catttcatct acctgttttt tgatgttagc tgaaatgccc ttaccctcat tgccaataat
     4861 caaagccagc ttgcctgagg tattccactt gtatgatggt gtaccagtta catctgtccc
     4921 gaagacccaa aagccatttg cttttagctg atccaatgct tggctaagat ttgtcacgcg
     4981 agcaattgga acatgctcaa cagctcctgt tgaggtctta gcaaccactg gtgtcacacc
     5041 aacagcacga tgcttaggga taatcacacc acaaacacct gttgcgtcgg ctgttcttaa
     5101 aatagaccca aaattatgag gatctgtcag cccatctagg atgagcagca agggattatc
     5161 ctcctgctgt gccagctcta gcagctcatc tagctcagta taagcaaagg ctgacactcg
     5221 aagcgcaaag ccctgatgaa cagctcctgc tgtcatttcg gtcaaagctt tcttttttgt
     5281 ccaagagata gacaccttct tactagtggc taaatccttg atgtgatcaa catgcttacc
     5341 acacagatcc tcttgaatgt aaagcttatt tccagtattg gctagtaggc tttcggtaac
     5401 ggcatggacg ccataaacaa tatccttggt ttcattgatt tctttagctt tcatggtttt
     5461 tattatacca cgaaagcaat aaaatagctc ttgctgctct ttttatttcc tgtgaacagc
     5521 tttgatgaca agagcaagta aagcagctgc tgtaattgca attagagatg atagcagcca
     5581 aggaaagcct ttttgctctt tatcttgggc tgtgctatca gaaagcatgc ccttgccttt
     5641 ctcagcagag tctattgatt tggcagctga tggtgtgttg cttgagcttg cctttaggac
     5701 cttatcagat cgatgattgg ttcttgtcat atgattggcg ctagcagtcg cgctaggcac
     5761 attttggggt tgctcagtgc ttgtcaccct gccgctagca gcgggtttag gctggttatt
     5821 agctggtact ggattgctgt ttttctgttc tgtctctggg gtatttttgg ttggctttcc
     5881 atcaaaatga ataggtgctg agctaccact aaaggccttt tctttatcag gaacactcac
     5941 tgatatacta taatcactaa cctttaggtt cgtaaggtca aaccatactg aaaaccggct
     6001 ttgaccagcc tgcatggtat aggctgtgct attaatcgcg ttgcctttgg catcctttag
     6061 taaaatagta gcctcagtgc tttggctaac tggctgactg gtagcaatgt tagcttcaat
     6121 aacgggctga tctgaacgca tacgagcact gacattggcc tcagctgctg cctgtgcttg
     6181 aactgctatg gttggttgat tgtcctgtgc tgctactgct gatacaaagg cctgtgagct
     6241 taacagtaac attgctgaaa taactaaggc tacgtttctc attggtttca tagacattct
     6301 cctatcattt tattatgact ctttcattat aaactattcg gaaaattttt caatagtttt
     6361 gttacgtttt tgttacaaat atttatttta tgtttcgtgt gtatctatat tgtgacataa
     6421 cttttaaaca caacataaaa acactctcat gactttgagc gatggcagat cgctagtgac
     6481 acagagaatg ttttagatga ttcatcatta tgattgagga ctgttctcca cctgcttgat
     6541 acaccactgg atcaacagtt ctagccgttc tgtctgacct gtcatatcaa ggtagcccat
     6601 aatagcttca aagcctgttg acatacgata ggttactaca tcagcatttt tagccttggt
     6661 atggctgttg gtattgcggc ctcgtttgta gatgtctttt tctttttcgg tcaatagttg
     6721 tgcttctagc atggcctgaa tcagagaagc ctgtgccttt gcagaaacat attttgttgc
     6781 aaggtagtgg agcttatttg gcttggtctg gccttggaaa atcagatgac gacgaatata
     6841 gtaagaataa acagcatcac caacaaaggc aagggcaatg ccattaatca aattgacatc
     6901 aactgaatta gccacgtatc cacctcacac cttcttttgt atccaacagc ttgatcccct
     6961 gagctgccaa ctgatcccga atagcatctg cccttgcaaa atctcgattg gcacgtgcct
     7021 cctgacgctc agcaatcagc tgctcaatct ctgtgtctag gctttctgct tcaaagacaa
     7081 tgccaaaaac agctagcatc tcttcaaatg ctgatttgac agcctcagaa taggcgccgg
     7141 agttaatcca ttttgccatg tcaaataaga ctgtaatccc atttgctgta ttaaaatcat
     7201 cattcatggc tgctttgaag gcagtgataa aggcagcaag ctggctagca tctgcagtgg
     7261 ctactgtggg ctgctgaagc gtgtttttca agtatttgag gttaactcca gcatcatgaa
     7321 tagctttttc agtaaaatta atcggcttac gataatgctg agtagccaag aaaaagcgta
     7381 gcgtttgccc atccaccgtc tttagcagat catgaacagt cacaaagttg cccagtgact
     7441 tagacatttt ttcgttgtca acattaacaa agccattatg catccagtaa ttggcaaaag
     7501 ttttgctagt ttttgcttct gattgagcaa tttcattggt atggtgtggg aattccaggt
     7561 ctgcgccacc accatgaata tcaatggtat ctcccaaaag ctcggttgcc attacagagc
     7621 actcgatatg ccagccagga cgaccggcgc tccaaggact tgcccaagaa atctcgccta
     7681 gctttgctga tttccatagg gcaaagtcca aaggatcttc cttgagagca gtttcggtat
     7741 ctgtacgacc actagcacca gcctccaaat cagcaatcgt tttattagcc agtctggcat
     7801 aatttgatgc ctttgccacg cggaaataaa tatcacctgc cgactcatag gcatagcctt
     7861 ttttgattaa agcagcgata aaggcaatga tctcgtccat atagtccatg acgcgtggat
     7921 ttttggtggc cggcttcaca ccgagtgcct tggtatcctc cataaaggca gcaataaatc
     7981 tgtccgccaa ttccttgggt gatacacctg attccttggc tgccttgata atcttatcgt
     8041 ctacatctgt aaaatttgaa atgtaattga ctgtatagcc tgcgtattca aagtagcgac
     8101 gaatcgtatc aaaggccaca gccgaacgtg cattgccaat gtgaatataa ttgtaaaccg
     8161 ttggcccgca gacatacata ttgaccacct tatcagttat tggtacaaac tctcgcagac
     8221 ttctggtcat ggtatcatag atttttatca tcacttttcc cttttgtttt tatccttttc
     8281 tcctagactg cgcaagctgt cagcaactga ggtaagcata gggctctaac tctcccgttt
     8341 tttggctgac tgcctctaga gaaaactatt aatcctgcct tgagggcttt ttctcatgca
     8401 ctcgaacaat ttgggctgga atgccaacga ccgtcacgcc agcaggtaca tcagtcaaca
     8461 caacagctgc agctccaacc ttagccgatt tcccaatctc gacaggaccg ataatttgag
     8521 catgggcaga aatcagtgcc ccctcacgaa cagtagggtg ccgcttccct cgatcttttc
     8581 cagttccacc aagcgtcact ccatgataaa gcatggctcc tttttcaaca atggccgtct
     8641 caccaatcac caagccagcc ccatggtcaa tgaaaacacc tgaagcaatc ctagctcctg
     8701 ggtggatttc aatctgtgtc caaaatcgcc aaaactggct atgcattcga gccagcagct
     8761 taaagccatg ctgccacaaa aaatgtgaca gcctgtgcgc tgccaaggcc tttaatccag
     8821 ggtaggttag gataacctct agggtgctac gtgcagcagg atctagttgc tttacaatat
     8881 caatattgtc cttccaccag cccatttaaa ctccttttat gtgtcaatat cagaccaatc
     8941 aacaagaatc tgctgatcat caaaggggtc aatagcaacc ccaaaggtct cgtctatgtc
     9001 attattgcca tttcttggct gataaatgtc tgctatcttc catgttaaga taacaccacc
     9061 tgatttccta aaaaggccgc caaactcctc ttgattgtac catttagcga agctctgaag
     9121 atttgaaaag gcaggaacat aacgcttccc ctctggagtt gacatggttg gaaaaagcct
     9181 gtcatagtaa tgctcctctt ccttagggta aacaaaggcc ggcaccagat aaagcctatc
     9241 cagggtatct gctgcgctat tgtcatcact catcaaggta ttcaaaatcg ttgtgtaatt
     9301 gttcataaac tgaatcatat cagcagactt gaacactgta gaattgccaa aatctccctt
     9361 tttcttgaga ttaaagccta gcccagcagc acctgcatga acagcctcct ccaagacagt
     9421 aagagcagag cgctctaccc aatactgagc ttgtgcactc ttttgctcct ctttaaaggt
     9481 cgccatgtcg tccttatctg tgaatacagg aaaaatcctt accccttcaa tctcaatagc
     9541 atagggcttt tttgctgccc acaccggata ctggtgaaaa gcattaacca aggccacgct
     9601 atctaaaaaa ttatcagggg cattgataaa ggctcttaaa cgaatatcta gttcatttgt
     9661 attagtcatg tttgccttct ttttttgctt ctgatttttc tggctttggc gggcgtggca
     9721 ccaaggcttt cattgatgcg tcaatacgtc ccttatcatc aaccttaata accttaacgt
     9781 caacctcttc accgatttca agaacatctg agacattggt agtgcggctc caagcaattt
     9841 cagagatatg caccagcgca tctgtcttgt caaagaggtt aacaaaggca ccaaattttt
     9901 caatacggac aaccttagca tggtagacct ctcctacctt agcctcacgt actaggctag
     9961 caatgatttc cttagcacga ttgatagcgt cctgatcact tgagtagatt gaaacatttc
    10021 cttcctcatc aatgtcaatc ttaacacctg tctcagcaat aatcttatca atggtttcgc
    10081 cacccttacc aataaccacc ttaatcttat caacatcaat cttgatggta tcaatctttg
    10141 gtgctgttgg tgccaattct ggacgaggct cagcaatggt tgcctcaatc aagtcaagaa
    10201 tttcaaagcg agccttttta gcctgcgcca aggcttcttc taggatttga ggggtgatac
    10261 cttcgatctt gatatccatt tgcagtgctg taatcccttg gcgtgtccca gcaaccttga
    10321 agtccatgtc gccaaaatga tcctctaacc cctgaatgtc tgttaaaaca gtataattgg
    10381 tcccatcaga gataagtccc atagcaatac ccgcaaccgg tgccttgatc ggcacaccac
    10441 cagccatcaa agcaagcgtc cctgcacaga tagaggcctg cgaggaagaa ccgtttgatt
    10501 ccaatacctc agccactaga cgaatagcat atggaaatgc ctcaaggctt ggaaggactt
    10561 gtgcaagagc gcgctcgcct aaagcaccat gcccaatttc acgacgccct gctgcaccgt
    10621 agcggcctgt ctcaccaaca gaatattgag ggaaattata gtggtgcaag aagcgttttt
    10681 tgtactcagg ctcaagccca tcaataattt gagtatctcc cattggggct agagtcaaga
    10741 cagacaaagc ttgagtttga ccgcgcgtaa agaggcctga gccatgcacc cttggtaaga
    10801 aatcaatctc agcagcaagc ggacgaatct catcaacacg acgaccatca ggacgaacct
    10861 tatcctcagt gatgaggcga cgaacctcag catgctccat ttgctccaaa atttcagcca
    10921 catcacgcat gatacggtca tgctcttcgt ctgctgcata acgctcctcg tatgcagcta
    10981 tgacacgctc cttgacagcc tcggttgcgg cttcacgtgc ttttttctcc tcaacctgaa
    11041 tagcctgctg caaatcagca ttgtaagtct ctatgatctc agcctgcaaa tcagcagcaa
    11101 cctgtaatag ctctacctca gccttttcct tgcccaccgc tgcaacaatc tcttcttgaa
    11161 aagcaatcaa ctcctgtata gccttatggc caaccaaaag tgcttctagc ataatagcct
    11221 ctggcaattc cttagcacca gattcaacca tattgatcgc atcttttgtt cctgctacgg
    11281 ttaactctaa taatgaagcc tcctgctggg ccttatcagg attgatgata aattcaccct
    11341 caacataggc cacctgaaca ccagcaatcg gcccattaaa aggaatatct gaaatcgata
    11401 gggctaatga gctaccaagc atagcagcca taggggcact agcatcttcg tcataagaca
    11461 ggacagtatt aatcacctgg acctcattac gaaagccctc agcaaacata ggacggatag
    11521 ggcggtcaat caagcgagcg gttaaggtcg catctgttga cggacgtccc tcacgcttca
    11581 tccagccacc gggaaattta cctgcggcat acattttttc ttcataattg acttgaagcg
    11641 ggaaaaagtc tcctgttgac atcttcttag acatgacagc agcagttagc actgtagact
    11701 ccccataacg aacgacagtg gcaccatttg ctcgcttggc tacttgaccg acctcaacaa
    11761 caagtggttt gcctgcaaag gttgttgtaa atgtttgttt tgacattctt tctccttgaa
    11821 cgagctagcc taccatagcc gtttgacccg accaaagctt gctagccttt tattttttat
    11881 ggctatacgt tgttttgcta caaagagcaa tctgtaagga attacacact cctctttgta
    11941 tcaaacgacg tatctgctac attttaccat aaaatagtta aaaattcacg accctaaaag
    12001 gcattcctag aaaaagtttg aaagggctgt caataccagc agcactctct tttatcacta
    12061 tagccctaca gccaagcacg ctaagccgct gatgacgcag caaaaaaaga cctgcct
//
LOCUS       DARYLD010000061        11417 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYLD010000061 DARYLD010000000
VERSION     DARYLD010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11417
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(72..2753)
                     /locus_tag="TU651_001611"
     CDS             complement(72..2753)
                     /locus_tag="TU651_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL0897584.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3090..3476)
                     /locus_tag="TU651_001612"
     CDS             complement(3090..3476)
                     /locus_tag="TU651_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL0897585.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3557..4858
                     /locus_tag="TU651_001613"
     CDS             3557..4858
                     /locus_tag="TU651_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0897586.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5083..5892
                     /gene="yidA"
                     /locus_tag="TU651_001614"
     CDS             5083..5892
                     /gene="yidA"
                     /locus_tag="TU651_001614"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL0897587.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5892..7106
                     /locus_tag="TU651_001615"
     CDS             5892..7106
                     /locus_tag="TU651_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL0897588.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7106..8341
                     /locus_tag="TU651_001616"
     CDS             7106..8341
                     /locus_tag="TU651_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL0897589.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8550..9308)
                     /locus_tag="TU651_001617"
     CDS             complement(8550..9308)
                     /locus_tag="TU651_001617"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL0897590.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9574..10770)
                     /gene="tuf"
                     /locus_tag="TU651_001618"
     CDS             complement(9574..10770)
                     /gene="tuf"
                     /locus_tag="TU651_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL0897591.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3425 a         2586 c         2262 g         3144 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 aggaaatatt ttttaaaagc cccaaatcat ctgatgattt tcagagcaaa ggtaactgat
     3001 gaccaagctt agactatcat taccgagata cagacagcag acacaggctg tcatcttagg
     3061 agactaacaa aggacttcct ctgctgagat caataccact tgatctccaa atgataatga
     3121 gcaaaggccg tctcagtgct gggctgtaat aaagcataat ctagggtcac tgtctgctgg
     3181 ccatgatcca agtgaaaatg gctcgtatct gtcaaaaatt gctggatccc tacaggcgtc
     3241 ggaatagcga tcaaggcttt tttgttagca agaaacctca tcacagactg aggctttgaa
     3301 aagcgactca tcgttagctc agcagcattg aacttaatca ctaccctttc gttgttatta
     3361 ttttgataaa ttagataggt agcatctgcc ttttgtctca aatccccagt atgaatctcc
     3421 ttgattagct ctgtttcctg accatagctg atcttgttat taatttcaat cttcatgata
     3481 tcttctttct cttgagtttt gctcgtctat tctaccaatt tctgaccatt ttcgcaattt
     3541 ctgctataat agaagcatga atgaaaaagt atttcgtgac cctgttcaca actatatcca
     3601 cgttaatcat cagctcattt acgagctaat caataccaag gaatttcaac gactaaggcg
     3661 aattaagcag gtgccaacaa cagcctttac ctttcatggt gccgagcata gccgcttttc
     3721 acactgtctt ggtgtctatg agattgctcg ccgtgtcaca gagatttttg aagaaaagta
     3781 tgcagacctt tggcataagg aggagagtct tgtaaccatg actgctgcgc tcctgcatga
     3841 tattggccat ggtgcttact cgcacacctt tgagacccta tttgatactg atcacgaagc
     3901 tgttactcaa gatatcatta ccagtccaga aacggaaatt aatgcgattt tgacgcgcta
     3961 ctctcctgat tttcctgaca aggtagctag tgttatcaac cacacttacc ccaataaaca
     4021 ggtagtgcag ctgatctcta gtcaaatcga ctgcgatcgc atggattatc tgctgcgcga
     4081 ctcttacttt tctgcggcta attatgggca atttgaccta atgcgcattc ttagggttat
     4141 tcgacctgtg aaagatggca tagcttttga tctcagcggt atgcatgccg tagaggatta
     4201 cattgtcagc cgctttcaaa tgtatatgca ggtttatttt caccctgcca gtcgagccgt
     4261 cgagctgatc ctacaaaact tgctgaagcg tgctaaggct ctctatccta gccagcagga
     4321 ctatttccaa aagacagccc ctggtctcat tccatttttt gaaaaaagtt tcacgcttgc
     4381 tgattatctt tgcttagatg atggtgtgct caatacctat ttccagcaat ggattactag
     4441 tgaggaccat atcctgtcag acctgtctag tcggtttatc aatcgaaaaa ttttaaaatc
     4501 tgtcaccttt gaccaagaat cacaacagga tttagagcgc ttgcgaaagc ttgttgagtc
     4561 agttggtttt gatcctgatt attatacagg tatccatgtc aattttgacc ttccttatga
     4621 tatttaccgt cctgagctgg aaaatccaag aacccaaatt gaaatgattc aaaaagatgg
     4681 cagcagggct gagctatccc agctctctgc gattgtcaaa gctctcacag gcacaagcta
     4741 tggtgataga cgcttttatt tcccaaagga aatgttagag cttgatgacc tctttacatc
     4801 agataaggaa gcctttatca gctatatctc taacggacac tttcatttta acaactaagg
     4861 accagccaag gtccttttgg ctttttcatc acgctctaga tttaaaatgg tatattaccc
     4921 gataaggaca gctagagctc tgacaagcac aagccaccaa acacagcaga gcctttaata
     4981 ttgccaaaat ctcttttgtt ttcatgacaa aagaacctat ttttagtaag atagaaggtg
     5041 gcaaatcatt gattacaaat cagaacaacc aaggagaatt ccatgtctat caaacttgtt
     5101 gccattgata ttgatggcac cttactcact gacgatcgac gcgttactaa tgacgttttt
     5161 gatgccatac aggaggccaa ggcccaagga gtgcatatcg tcattgctac gggacgtccc
     5221 attactgggg tcatctcatt attagagcaa ttgcaattaa atcaaaaggg agatcatgtc
     5281 atcaccttca atggtggact gattcaggac actgcaaccg gtgaagaggt ggttaaagag
     5341 ctgatgacct acgatgatta cctcgacata gaatatttaa gccgcaggct aggcgttcac
     5401 atgcatgcca tcacaacaga gggcatctat actgctaacc gaaatatcgg caaatacact
     5461 gtacgagaag caaggcttgt ggacatgcct gttttttatc gaacacctga ggagatggct
     5521 gacaaagaga tcgtcaaaat gatgatgatt gatgagccaa accttttaga tgaggccatc
     5581 aaacagattc ctcaagcctt ctatgacacc tacaatattg tcaaatcaac acctttttat
     5641 ctcgaattaa caccaaaaac tgtcagcaag ggcactgcta ttggtcacct tgccaaaaag
     5701 cttggcattg acatgtccca aacgatggca atcggcgatg ctgaaaacga tcgagccatg
     5761 cttgaagcgg ttgctaaccc tgttgtcatg gaaaatgggg ctcccgagct gaaaaagctg
     5821 gccaaataca tcaccaaatc aaacaatgac agcggcgtag cgcatgctat tcggaagtgg
     5881 gtattaaact aatgtataca tataaaatcg gaatttcagc taaagagcac gatcagtttg
     5941 tcctatcaca tcctcaggtc aatctgctgc aaagcgctca ttgggctcag gtaaaggata
     6001 actgggagca tgagctcatt ggtttttacc aggatgacaa gcaagtcgct gctgctgctt
     6061 gccttatcaa gagactcccc ctaggcatga ccatgattta cattcctcga gggccgatta
     6121 tggattattc tgactttgag ttggttaact tcgtcatgac tagcctaaag gcttatggta
     6181 aatccaagcg agctctcatg attaaatacg atccttcctt gtttatcagt caggccttaa
     6241 taggtgaaga aagaaaggac aatgacttca ccctctccat tattgatttt ttaaagacca
     6301 tcggtgttga atggactggc aggaccaagg agcttgagca aacgattcag ccccgctttc
     6361 aggccaacat ttacgccaag gactttaagc tccaaagctt atcaaaaaaa gccagacagt
     6421 ctatccgaac tgctcaaaat aagggagtcg agattattat tggctcaaca gagctacttg
     6481 aagacttctc agcactgatg aaaaagactg aggagcgaaa acacatttct ttgcgtggca
     6541 tttcctatta tgacaaatta atgaccactt acgctaatca ggcttacatt accatggcta
     6601 gattgaacct tcccaagcaa aaagcgctca tacagcagca attagaggaa gccttgagca
     6661 atcagcaggc ctttacccag cacagtaagc caggtaaggt cgcagaaaac caaaatacca
     6721 ttaaaaggct tgaaaaggaa ttggcttttc tagataagga aatacaagca ggtaaaagcc
     6781 ttgtacctct agcagctacc ctgacactga tctatggaca gacctctgaa aacctatacg
     6841 caggtatgga taatgacttt cgccaatatc aggcagccct cttaacctgg tatcataccg
     6901 cagaagaggc ctttaagcgc ggttgtcaat ggcacaattt agggggcgtt gaaaaccaat
     6961 tagatggtgg gctgtttcag tttaaagcaa gactaaaccc agctatcgaa gaatttgcag
     7021 gagaattcag cattccagtt ggacctatct caaaggtggc catgatagcc tacaatttga
     7081 gaaaaaaact aaggagtaac ccttaatggc tttagatatc attgacaaag aaacgtttgg
     7141 ctcattttgc agtcaaatga agtataaatc cttcattcaa tctatagaaa tggcagagct
     7201 gctgcaaaag cgtggttatc agacacaata ccttgcaatc agtgaccaga aaaacattaa
     7261 gattgcagcc attctctaca gtataccaat gaccggcggc ttacgcatgg aaatcaactc
     7321 aggtccagta gtggctgata cgacctacac aacagccttt tacaaagcct tacaggacta
     7381 tgccaagcag cagggagcac ttgagctagt catcaagccc tacgatacct atcagacctt
     7441 taccagcgat ggtcacccaa acgatgatga aaagccagag ctgatcaaga ccttgacaga
     7501 gctcaatttt acacatgatg gcctgctaac aggctaccat aatggtgaag gagattggca
     7561 ttatgttaaa gatttaagcg gattgacctc tgctaatgtc atcaattcct tcagtaaaaa
     7621 gggcaaggcc ctgctaaaaa aagccaaaac ctttggcatt aagctacata agctcaatcg
     7681 tgatgagcta acacaattca aggaaattac tgctgctaca tctagtcgaa gagattatac
     7741 cgacaagtct ttatcttatt atcaggattt ctatgatagc tttggggata gctgtgaatt
     7801 tatggttgca accctcaatt ttgatgacta cctgaccaat ctagagcaca gtcaagacaa
     7861 gctaaagcag cgcattagca aattagaggc agacctagtt aaaaaaccaa aatcagaaaa
     7921 aaaacaaaat caactacggg aactctccag ccaatttgat acctttcaag ttcggatagc
     7981 tgaagcacag gagttaattg tcaagtatgg caaaaaggac attcctctag ctggtagtct
     8041 ctttgtttac accccgcagg aggctgtcta tctcttttct ggctcctatc cagaatttaa
     8101 caggttctac gcgccagccc tattacagga acatgtcatg ctaagagcga ttgaaaagaa
     8161 aatcagctgc tataattttc ttggtatcat gggcgaattt gatggctctg atggtgtttt
     8221 acgctttaag caaaacttta acggctatat cacacgaaag atgggaacct ttaggtatta
     8281 tccaaagccc ttcaagtaca aagccataca ggccatcaag acaatgcttg gtcgcagcta
     8341 agtcaagcta gtggctaagc agccctttaa gccttccaat ggctattgac cacaataata
     8401 aatccttgat tgtcttactc agaacccctt tagtaaactt tccaacctaa aaataaggta
     8461 taggtgatcc catgctcaag aaggctatca agcaaaccaa aagctcaagg aattaaccct
     8521 tgagcttttt agctatatta taattgtcat tagttgacaa aatcaagcaa ggcaaggaag
     8581 ctatctgctt ctagtgatgc accaccgaca agagctccgt caacatccgg acaagccatg
     8641 tactccttaa tgttttcagg cttcacagaa ccaccatact gtacacgaac cttgtctgcc
     8701 acctcttgac caaagtcagc agcaaccaca tcgcgaacag ccttacacat gctttgagca
     8761 tcttcttgag tggcagattt accagtaccg atagcccaga ttggctcata tgccaatacc
     8821 aatgaagcaa cctgctcagc agatagcccc tctagagccg cagacacctg tgcaccaaca
     8881 aaggctactg ccttgccagc ctcataggtc tcaagagact caccgcagca gataattggt
     8941 gttaagccat tagcaaagat ggcttttgct tttttattaa tatcttcgtc tgtttcgtgg
     9001 aagtaatcac gacgctcaga gtgaccaatc accacataat cagctcccat gtcagcaaga
     9061 accttaggag aggtttcgcc tgtataagcg cctgaatttt caaaataaca gttttgcgca
     9121 gcaaccttaa ggacagagtc cttagcagcc tcaattgtag tgaccaagtc aacagctggt
     9181 gctgctactg caacgtcaac aagatcgttt gaaggtaatt tgcttactac tgccttaaca
     9241 aaggcttttg cctcttgagg atttttgttc attttccagt taccggcaat aattggttta
     9301 cgtgacattt cacatacctc ttcttttttt atttacatct actattctag cacaatttct
     9361 atgctaataa aagaaaatgg ctgactttta ggaatatttt cacaaagaaa agagtatttt
     9421 ctgaaaccat tttcaaacga taaggcttat cgattagcta agcagacccg ctaagtcctc
     9481 atctttataa acagagcaaa aagagccctt aaaacaaggg ctctcacaat taagctgtct
     9541 gactttaatc gttatctggg aacttaatca aaattaagct tcgatttctg aaacgatacc
     9601 tgaaccaaca gtacgtccac cttcacgaat tgagaatgta gtaccttgtt ctacggcgat
     9661 tgggtggatc aactcaacgt caatagtcac gttatcacca ggcataacca tttctgtacc
     9721 tgctggaagc tcgattgaac ctgttacgtc agtagtacgg aagtagaatt gtggacgata
     9781 gttgttgaag aatggtgtgt gacgtccacc ttcttcttta gtaaggatat atacttcacc
     9841 tttaaattta gtgtgtgggt tgatagaacc tggcttagca ataacttgac cacgttcgat
     9901 ttcatcacgt tgtacaccac gaagaagaac accaacgttg tcccctgcaa gaccttcgtc
     9961 aagctgttta cggaacattt cgacaccagt aacaactgct tttttgatct cgtctctgat
    10021 accaacgatt tcgatttcgt cgttaacacg aacagtaccg cggtcgatac gtcctgaagc
    10081 aacagtacca cgtccagtga ttgagaatac gtcctcgact ggaagaagca atggcttgtc
    10141 tgtgtcacgt tctggttctg gaatgtatga atcaacagta tccatcaatt ccatgatgat
    10201 atcttcgtat ttgctgtcgc cttcaagagc cttaagcgct gaaccttgga taactggaag
    10261 gtcatcacct gggaaatcat attctgaaag aaggtcacga atttccattt caacaagctc
    10321 aagcaattct tcatcgtcaa caaggtcaac cttgttcatg aacacgataa ggtgcttaac
    10381 accaacctga cgtgaaagaa ggatgtgctc acgagtttgt ggcattggtc cgtcagttga
    10441 agcaactaca aggatagctc cgtccatttg agcggcacca gtgatcatgt ttttaacgta
    10501 gtccgcgtgt cctggtgcgt cgatgtgcgc atagtgacgt gtagcagttt cgtactcaac
    10561 gtgtgcagtg ttgatagtga ttccgcgttc gcgttcttct ggagcagcat cgattgaagc
    10621 gtagtctttt ggttggttaa ctgagcttgg tagacgacgt gcaagaacag ttgtgattgc
    10681 agctgttaaa gtagttttac catggtcaac gtgtccaatt gtaccaatgt taacgtgggg
    10741 tttactacga tcgtattttt cttttgccat tttaggaaaa gcctccaata aaatatattt
    10801 tatagataga cggtaggcaa tacagtctaa ctttacctta ctattgtagc aaattataag
    10861 gaaattgcaa gcagtaagtg aggaacttta acggatttat cgttatccct gatttcaaca
    10921 accctagcat acaaaaaagg aaagagtttt cgtcttctcc caggcaatcc gctctttacc
    10981 gttttttgct tttcaaggct ctaggcattt gcatactttt ggaggagagt tgaattgtta
    11041 agagataatg cattcggaga tctataaatc ataggcagga cataccgatc caaaactaag
    11101 atagtggaga cttgatggtc catgacagac gcgcgaaaca gctatttccg aatgataata
    11161 tagatgagag tagacacttt caacgttctt cctatagtaa aagctatgca aaatcctaca
    11221 tattcttgaa atagctgaac attgaaatac aggaagcttt attttattgc taaaaatctt
    11281 tcatgtgtct atcgtggtcg atgatcgcag agttagcttg ttaatatttt ctatcttttt
    11341 tattatattt tgttaatttt ataatctatt taactatttt aaaaatttac ttatttaaat
    11401 cacaaaacac tgttata
//
LOCUS       DARYLD010000062        11378 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYLD010000062 DARYLD010000000
VERSION     DARYLD010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11378
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..527)
                     /locus_tag="TU651_001619"
     CDS             complement(<1..527)
                     /locus_tag="TU651_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL0897592.1"
                     /translation="MVTKGDREKLSSFSLQIFKEGGEAMDFDYFYNREAERFNFLKVP
                     EILVDGEEFKGLSAEAIILYSMLLKRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNIS
                     KPTAIKTLDELDSKKGIGLIERVRLGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSE
                     VKDFNLRSKENELQEV"
     gene            complement(542..823)
                     /locus_tag="TU651_001620"
     CDS             complement(542..823)
                     /locus_tag="TU651_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897593.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(843..2474)
                     /gene="rlmD"
                     /locus_tag="TU651_001621"
     CDS             complement(843..2474)
                     /gene="rlmD"
                     /locus_tag="TU651_001621"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL0897594.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(2552..3982)
                     /locus_tag="TU651_001622"
     CDS             complement(2552..3982)
                     /locus_tag="TU651_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL0897595.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(4181..4675)
                     /locus_tag="TU651_001623"
     CDS             complement(4181..4675)
                     /locus_tag="TU651_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL0897596.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(4668..5951)
                     /gene="aroA"
                     /locus_tag="TU651_001624"
     CDS             complement(4668..5951)
                     /gene="aroA"
                     /locus_tag="TU651_001624"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL0897597.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(6084..7022)
                     /locus_tag="TU651_001625"
     CDS             complement(6084..7022)
                     /locus_tag="TU651_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL0897598.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(7024..7884)
                     /locus_tag="TU651_001626"
     CDS             complement(7024..7884)
                     /locus_tag="TU651_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL0897599.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(7901..9184)
                     /locus_tag="TU651_001627"
     CDS             complement(7901..9184)
                     /locus_tag="TU651_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0897600.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(9177..9731)
                     /locus_tag="TU651_001628"
     CDS             complement(9177..9731)
                     /locus_tag="TU651_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0897601.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(10025..11314)
                     /locus_tag="TU651_001629"
     CDS             complement(10025..11314)
                     /locus_tag="TU651_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL0897602.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         3229 a         2703 c         2048 g         3398 t
ORIGIN      
        1 acctcttgaa gttcattttc tttacttctg aggttaaaat cttttacttc tgaagtaaaa
       61 ttttttaact tctgtaagtc atcttctttt acctgaaata tgctcataaa atctttgaca
      121 taaatgatat tcggctttcc aagtccaagc cgtacccgtt caatcagtcc aattcctttt
      181 ttactatcta attcatctaa tgtttttatg gcagtcggct ttgagatatt tcttcttttc
      241 ataatttctt cgactgtgaa atagataaat accctgcctt ccttatcaat ccagttattc
      301 ttaaaggaca ttcctgtccg tttaagaagc attgaataaa ggataattgc ttcagcggat
      361 aatcctttaa attcttctcc atcaaccaat atctccggta cttttaagaa attaaatctt
      421 tccgcttctc tgttataaaa atagtcaaag tccatcgctt cacctccctc cttaaaaatt
      481 tgcaaagaaa aagacgatag tttttctcta tcgcctttgg taaccatttt tatgaaattt
      541 tttagattga ttttattgct tcattgattc ctttaaagaa tgctataact gctgctccaa
      601 ccatcggtat tccataagga cttaacaaaa atcctaatac taatgcctca atgccaagtg
      661 atatatcttt ttgcataaat gatcctattg cagcaactat acacatcagc attaagaaat
      721 acagaatagt tgttcctatg ccaagtataa atgtcagaaa ggcagtaagg acactaagta
      781 gcaagctgaa tggaaacaat attattttta ttatccacct catataatac ctctcctttc
      841 tcttaaatca ttttaaagtg ccttaacgca tccataatag ctttttcttt ctcaggtgta
      901 cactgcggaa taacttgctt atcttttttt gatttattgt aattctctct aagttctatt
      961 ccacattttc tttttatctg tgctatatat agtgttgaaa ctttaaaacc aaatttttct
     1021 aatatatact ctttaatttt agcataggta gccttgcttt ctgcacttgt caaatcaagt
     1081 tcatcaagct ctatttcaac acttatatac ttatcgacat taagtttgga caataatgct
     1141 accgtctcga catgatgtgt cattggaaac aagtctactg gctggacttt ctggagttta
     1201 tagccgagtt cctcgtagcg cttgatgtca cgcgccatgg tggcggggtt gcaggatata
     1261 taggttattt tgtcaggctg catcgctgca ctggccttga taaagctctc agttagtccc
     1321 tttcgtgggg ggtctacaat gataactgtt ggctttatgc cctcctgaca ccagtttgcc
     1381 atcgcatttt cagcgctgtc agcgacatag taggcattgg taataccgtt tagcgctgca
     1441 tttttctcgg catcacgcac tgctgcttcg atcacttcga caccgtatac tgctttgact
     1501 tctttagcaa aggatagccc gatggttcca atgcctgaat aggcatcaat caccacatcg
     1561 tcagcggtca attcagaaaa atcaatagct gtttgataga gcttttcagc cattgttgta
     1621 ttgacctgat agaaggactg agcagaaata cagtattgat tgcccaagat cgtatctgtg
     1681 attgtctctt ttccataaag ccttgtaaac gccttaccaa agataacatt agtaggcttg
     1741 tcattgatat tttgcaggat agaagtaatc gctggaaatt ctgcgacaag gctatcaatc
     1801 atctggttga tacgaaagat tttaggtcgt gttgtcacta aaaccagcat gatttctcct
     1861 gaataatgcc cacgacgaac cacaagatga cgaatcaggc ctgactgctc cttttcgtca
     1921 tagggcttga tgtcaaaacg gcgcaaaagg tcgcgtgtaa aggcaatcaa gcgatcaatt
     1981 tccttatctt gaatgtaaaa atcagaaatc ggcactagct catgagaatg cttacggaaa
     2041 aaaccagtct ctagctgacc attgacacga cgaacaggaa cctgggcttt atttcgataa
     2101 gcataaggat attccatacc aattgtttct ttgacctcaa cattgctaat ccctgcaatc
     2161 ttatagagac tatcctgaac ctgcttttgc ttaaagagca gctgctgcgg ataaagcaag
     2221 tgccccaaat cagcaatacc tgtacgcaga taggtcacat ccagcttttt ttgacgcatc
     2281 ggtgaggttg ttagataggt ctctaccttg ccaaagccac tgtttttatt gacctttagg
     2341 acacgcatct gaatgatctc acctggaaga gcattttcaa caaagaaaac aaagccttca
     2401 tgcttagcga ttcctaagcc atcatggctt aaatcagaaa tttccacctg aacaatatcg
     2461 tttttactta acatttactt tccttttctt ttactacact aatcactcaa aaaagaagag
     2521 caaccatcgt tacccttcat tatagcatat cttagcgtaa tcccagctta gataatcgat
     2581 tttgatactt agcaaaatca ataaagagag cctgaccacc atacatgtca tattcatcaa
     2641 tccaatcccc attttcagga atcgtcacat gctccacacc gtttttgcca ttagtcaaga
     2701 cggacactcc atttttaagg acaaatggga aggagacatt ggttgaggtt agggcataaa
     2761 tcttaccaat agctgctgag cccgtaaaga gcttggttgg atccttgatt tgagacatga
     2821 tagcagccat cacctgctgc tgacgtacgg tccgaccaaa atcaccctca tcgtcctttc
     2881 ggaagcgagc atagttgagc agggtacgac catccatttt ttgctcacca accgttatgg
     2941 tttggttggg aaccactccg tctttcattc gtaaatcatc tggtacatca acagcagcga
     3001 ctgcttcgcc atttacagta gcaaatttgg catcaatggt aacaccatct ggaaacagtg
     3061 tgtcaatagc ctcagcaaag gtttcaaagt caaccatgac ataatattta atgtcaatat
     3121 caaaattatg cttgagtgtc tgacgcacaa attctgctcc ttgatgattt tcctgctctc
     3181 ctaaattaaa ggaggcgttc aattttaaat cataggaatc ctgattatta tagctatagc
     3241 caggaatatt aaccaaggta tccctcatga aggagaccat tttgatttta ttctccttat
     3301 tgccaacatt aaccaccatg attgtatctg ttcgagcatc tgttgagcct tgcgtaatcc
     3361 tctggtctga gcctagaatt aaaatattag tgccatcgct agtatcctga ccatgaaaga
     3421 cctgcgaaac tgctggctta taattggcct tgttagtaga cacgtccatc attcccttga
     3481 aaaacatgaa agctatccct gcaacaagca gcagcaacaa gaaaaagagt attctgaaaa
     3541 aacgtctcag acgtcccttc ttttttttcc ttctaccctt tttaggcata gcctcaggcg
     3601 caagctcctc atagatcgcc tgatctgggt catcatagaa gtcctgctga ggggctagta
     3661 ttggcttttg ctgatgcctt ttgctacgtc tttctgatct tggataaaga ggcaggccat
     3721 taggcccagc ctgctgctca tcactcatat cataagcatc agcattatcc tgtgaagctt
     3781 gagcataatc gtcacgccca cccctagtat aatgagtcaa ggagcgctga gaacgagaag
     3841 gcatagccct tgactccatc tttgacttta aaaaggtaaa ttctctgcgt tcagtctcag
     3901 tcaaataatt taaatttctt aataaataaa aatatcgtaa ttcttcgtgg tggcttagac
     3961 cacccttttg gtatctcgtc atgctcttcc aactcttagt attctaatac aatttcttct
     4021 attctttgtc taatgattct attataacct atattaacga gattgtcctc taaaatcgtt
     4081 agaattcaac tttatttcaa cctatatatt agcttttcat acctaatcat taagaaaagc
     4141 tgggctgcga ataggaggcc aaaagtctaa tcctcagcag ttacgacata ttggcaatga
     4201 ttgctgcaac ctcctttggt gttctatgct caacattaat cactttgtct gccaatccct
     4261 catacaaggc catgcgctgc tgaaaaatag catagagttc tgcttcagaa tgatttaaaa
     4321 acagtggtct ttggcatagc ctatcttttt taagccgatc atacaaagcc tcaaaggagg
     4381 ctgttaagag gatattattt ttgtgatttt ttctgattaa ttctcggttt gccttactaa
     4441 ggacaacacc tccaccagtt gatacgatag tctcattatc aagtgccagc acttcctgta
     4501 aggtatctga ctcaagcttt ctaaaggctg cttcaccacg ataggaaaaa aatgctgata
     4561 tgctcatgcc tattttagcc tcaataagcc tatccatatc caaaaaatgc tcatctaatt
     4621 gggctgcaac tgtcgtcttg ccaactccca taaatcctaa tagcagctta gtcatgccat
     4681 aacctctcta aatccttaaa aaagtcagga taagaagtca ggatagcttc tgctcgctct
     4741 agggtgacct gtccttcttc aaccagtagg gctgcaatag ctgtcatcat gccaattcta
     4801 tgatctccac aggtactgac agctgcacca tgtaatggtg ttttgcctct agtcaccata
     4861 ccgtcctctg tcgcctgaat atcagcaccc atctgtccta atacatcagt aacagcctga
     4921 atgcggtcag tttccttgac ccgtaattct tgagcgtccc tgatataagt cgttccctgt
     4981 gcctgagttg ccagcaaagc aataacaggc aattcgtcaa tcaagcgagg aatcaagtca
     5041 ccagaaatct caatgccctt tagggtggaa taagacactt ttagggtagc agcctgcctg
     5101 tccttatcaa cagcctgata ggagatacga ccacccattt tttcaatgac ctctaaaaga
     5161 cctgtccgcg taggattaat ccctacattt tcgagcacaa gatctgaccc cggaacaatc
     5221 agaccagcag ctaaccaaaa ggctgcgcta gagagatcgc caggaatctg taaggtctgt
     5281 ccctgcaaac gctgcggtcc tttgatactg atttgctttc cagctactga gagctttcct
     5341 ccaaattgtt caatcatctc ttcggtatga tttcttgtca attccttttc aaggataaca
     5401 gtctctccct gtgtctgcaa agcagctaat aaaatagcag acttgacctg agcagacgct
     5461 acaggcagct gataatggat cggccgcaac tcctgacagc cctttacaat tagtggtgga
     5521 agctcttttt ctccttgacc agatagctct gctcccatta gagacaatgg tatggtaata
     5581 cgatccatag gacgccttga taggctatca tctccaagca gctgcaccga aaaatcctgt
     5641 gctgctaata gccctgcaag caggcgcata gaagtacctg aattgcccat gtctagaggc
     5701 ttttgagctg gctttaggcc tttaaaacct cttccttcaa tgattaaact atcagctgac
     5761 tcgtaaatgg tgacacctag gtctcgaaag gcttgaatgg tggctaaaac atcttgcccc
     5821 cttaaaagac catgaatcac cgtttgcccc tctgctatag caccaaaaat gactgcacga
     5881 tggctaattg acttgtcacc tggtaccctt agacgtcccc taagcgcctt agcttttgtt
     5941 tttaatttca tcattactcc tatttttagt acaccagcat tagctcagca aagcaaataa
     6001 aagaaaatga agtaaggaca agggccctta ccccatcaac taatcaccaa gcaccgtctt
     6061 gtttttcatt ctaagacaag ccgctatttc ttgggcggcg caccatcatt gcctaatgtc
     6121 tttttgatga gagaaacaac attgccgctg cgcccctcta atttgccgat ggatagctct
     6181 tgataggtag cgttaaaaac cgcccccata atcaatatcc ttgccaggaa aataaaccat
     6241 agcatgatga taaaaatcat caccgaacca aaggttttaa tatcgaccat tcgctccaca
     6301 ttatgcacca cataattacc aaccatattg ctcaaaaaaa tcatgacaaa ggtggtaaaa
     6361 aatgttcctg gtaagatata cctgattttc ttgattttga tatttggcaa caaaaaataa
     6421 agcaacatca gaccaacaaa tataatcagt atcgtaatcg gctgaatcag gaacaaaaag
     6481 agcgtcgtga tgttatcatt taagtgataa tgcctatcca gcacctgaat cgctgcctta
     6541 gaaaaggttg aaaaaatcaa ggcaaaggtc aacaaaaaca ggatcagcag gctcgtcagc
     6601 aagcctacca aatgaccgag caaaaagtca cgatgctcag aagcatcata agccttatta
     6661 aaggcctttt gcagagaggt taggcttcgc gacattgtcc aaagccccgt caaggtcgct
     6721 actcccagca cactgcctga tggcttagaa aaaatattaa ccacaatgga ggaggcagag
     6781 cgataaatat ccttaggcag ctgctccttc attaagcgta ataaatctga aatatcaata
     6841 tttaaataag gaaaaatatt agccgcaatg acaatgagtg gaaaggctgt caaaataagg
     6901 taataagcaa ctgcaatcgc tgacaaatcc atctctgcac tctgaaaatg gcgcataaag
     6961 gcttggattg gctcatattg ccattttgat atgaccttgt ccaagaattt ctttattgac
     7021 attctaataa gttctttctt cgccctgact agttaaaatc actggaccat cctttgtaat
     7081 cacaaattga tgctcatact ggcaggacaa gccaccatca agtgttttat gggcccagcc
     7141 tgttttcata tctgtattaa tttcccatgt gccagtattg atcatcggct ctacggtgag
     7201 caccatgccc tccttcagac gtagtcctct tcctgctgta ccatagttag gcaccatcgg
     7261 ctcttcgtgc atggttggtc caacaccatg accaacaagg tctcgaacca caccgtagcc
     7321 atgactttca gcatattgct ggactgctgc accaatgtca ccaatgcggt tccccacaac
     7381 tgcctgctcg atcccacgat acatggcttc cttggtcacg tccatcagcc ttttgacctc
     7441 atcagacggt gtacctacag cataagccca gcaggaatca gccaaaccac ctgtataaga
     7501 ttctgtccac ttcttcattt ctgccacatt atcaaaatcc aaggccgcta catcaacgac
     7561 agccttatca agtggctcac ttagcaccat atctacctta agcaaatccc cttcctgtag
     7621 aatataatgg cgcggaaaag catgtgcaac ctcatcattt agcccgcagc aggtagcgta
     7681 aggataatcc attaattggc catcaacacc gatctgtaaa ggaagcacat tgtcctcctt
     7741 gcagcgcctg cgcacatatt cttcgacctc ccacatgtca accccaggct taatgatctg
     7801 tctgaggcca atgtgaatcc cagcaagaaa gtctcctgct ctatccatag cttctatttc
     7861 acgcgcagat tttaatgtta tcattgtttt tgtttctcct ctaattaagc ttagttgtaa
     7921 taatggcttt agcaatcacc tgatcatcaa ccatgacctc catatcaagt gtactgcttc
     7981 ttctattttc agttataatt ttagggtata tcctcaattg atcatcaatt tggacagcat
     8041 gtagaaagta tatcatcatt tgctcgataa tgatattttt ttggtgtttt ttcgttagca
     8101 ctctgacact gatttccttt aagaattcag caaccactcc atttgacaga ttgccagcac
     8161 tatcaatcat ggtaggctca atcatgacct gataataatc caaggtctcc tcaaggcttg
     8221 atagcatttg ctggctatag gtgtaaagat ttcccggctg gtgattcggc aggttttcca
     8281 tagcctgtcg tctggtaata atccccagca gaaaatgatg atcatcaact actgggagca
     8341 tgttcaaatc ctcaaagatc attttttgac taatattagc caggctagca ttgggctttg
     8401 cagtgatagg atttggagac atcacctgct caagtctagt ctcagcaggc tgatccacca
     8461 catcacgcat actgaccaca ccaaccacct gatcaagcgc atctacaatt ggaaacctta
     8521 cttgacctgt ctttttaatc agtgcattaa attcctcgac agtgtctgtc tcataaaggc
     8581 agccgtattc ttcaactgga atcagaacct gagcaactgt ttttaaatca gtcttaatgc
     8641 gaatattaga caaggcatgg ttaatcatcg ttgccactgt aaaggtatcg taatgtgtca
     8701 ccataaccgg aataccttgg ctatcagctg tttcaataac ctgcttagac accggaaagc
     8761 cacccgtcac taagatagca ttgtgatttt taagggctaa cagttggata ttttcacgat
     8821 cgccaacaat caaaagccct cctttgatca aataacggtg aatattttgc tgggtcatcg
     8881 ctccaataga aaacttgcta aactcatgtc ccaaaccagc atgaccggct aaaacctcag
     8941 aatcactgat ccttgcaatt tcggcatagg tcaaacggtc aatacgaacc cgtccttttt
     9001 tctcaatgcg gacagtacca ctacgcggct tggtctcaac aatcccccga ttttcagcct
     9061 ccttgatcgc tctataggca gtaccatcac taacctttaa atgatttgaa atacttcgga
     9121 cgctcacacg ctttccaata gcaagtcttt ctaaataatc taaaatgtct tgatgcttac
     9181 tcataatgat actcacctat cgttagttga tattctaaat aatctcgtat gtgatgacta
     9241 tgccgatcac tgcccttaaa ttgctttgtt aatcgaaagc cggctttttc agcaaccctc
     9301 tggctggcct tgttttccag atgtgtcaca atgatcagct gcctcaagcc aaactcctga
     9361 aaagctaaaa aggtaagcgt ctttaagacc tcggtcatta agccctgtcc ccaaaagggc
     9421 tgcgctaaaa aatagccaat ctcagcactt gcctgctgct tatcatattt ttctagtcta
     9481 atagagccaa gcatgctatg gctggtctta tcctctatta accagactcc caagggctct
     9541 ttcataaaag cattgaccat taagaaatca ctctcagcct tggtcatgct ctctggaaac
     9601 acaaactggt aatggctgtt atgactgatc atatcataaa acggctgatg atctgcatat
     9661 tgaaagggcc tcaagagcag tcgttgcgtc tcaacaaaag caaaccttgc tagctgtgtc
     9721 caaatatcca tagcctcccc ttcaacatgc ctgtaatact attattatag cagatatcac
     9781 ctaaacattc tataactgtc atgagttttg ccatgatgat cataataacc tgacaagcca
     9841 tatcatagct caatcagact ctaagctgtt aaactattac taacagtcaa aaccaaaaaa
     9901 gagaagaccg tctgatcttc tcttgctatc ttatctgcta atgcttaaat gggctacatc
     9961 atagaaaagt cctatgagta agctcatcct tctaaggcta aacatgcttc cataaataca
    10021 ctgcttagtc ctgctgacgc tttgaagtca ctgctaaagc acctgcactc gccataatgg
    10081 caagagccgc tgctgtaaag aatggattag ccttctcacc agtcgttgga agagtcttag
    10141 ccttttgctt atctttttgc ttagctggtg ctgtcttagt tgctggtgta agcggtgtca
    10201 acggaagaga agctgatggc ttttctggat cagctggact ctcctctaaa gcctcagtga
    10261 ctgtaaatgt ctttgtagca gcgtcataag cccattcacc agtaacgcca ttgtcattgg
    10321 catattgcct gaaggtctgc tcggctgtgg ctgcgtctac tgccttggta gctgtttcac
    10381 ctgagaaggt aaccccctta ataacaagcc tataggtggt caaagctggt gttaattctg
    10441 ccgcctcaat agtctcagct acaggctgtt cagtgactgt aaatgtcttt gtggcagcat
    10501 cataagccca aacgccgtct acaccatttt tattagcata gtctctgaag gtctgctcag
    10561 ctacagctgc gtctactgcc ttagtagctg tttcacctga aaaagttgct cccttgatga
    10621 caagcttata gctagtcaag gctggtgtta gttctgctgc gtcaatgacc tcagaactcg
    10681 gtagagctga taaaatctct gccttaagcg cattgacacc ttcaacagtt ttggctttgt
    10741 tgattaaggt cacatagtaa tcactaatgc catactgctt tagttcattg atagcagctt
    10801 ctttagcctc caacaaggct gctcctgtaa tgtccgcaat agctgtatga gcatcattaa
    10861 tggctgcatt cacttgatca actgaagcag catctgccac cttagctgct gcagcaacta
    10921 gagctagctg aaccttttga tcgcttttgt gctgatcact taaggcattg attgttctgt
    10981 aagcctcacg tcttgcttca tcaagctgaa caccagcaac agctgccttt gctttgtcaa
    11041 gagctgcttt agcctgatca acagtatctg cagcaagtgc ctcaactcca gcattagcaa
    11101 gaacagcctg aagctcttga ttgtcagcgt agtcatcact cagctgattg atttccctaa
    11161 cagcttctct aatgaaggct gttgtaggct ctaacactgt tgctgcgtct aaagcaccca
    11221 ctgaagtcgt tccaaccaga aaggctgccg acactgaagc taaaccaaca gctgattgac
    11281 gtaaaaagta ggataccttt ttgttttttt ccatttttcc tccctcgctt tttgtaaaaa
    11341 aaactttgac actaaaaact attaatgtca cttctatt
//
LOCUS       DARYLD010000063        10996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYLD010000063 DARYLD010000000
VERSION     DARYLD010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(32..1213)
                     /locus_tag="TU651_001630"
     CDS             complement(32..1213)
                     /locus_tag="TU651_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0897603.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TU651_001631"
     CDS             complement(1297..2532)
                     /locus_tag="TU651_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0897604.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TU651_001632"
     CDS             complement(2854..4092)
                     /locus_tag="TU651_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL0897605.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TU651_001633"
     CDS             4400..6376
                     /locus_tag="TU651_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL0897606.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TU651_001634"
     CDS             6440..7939
                     /locus_tag="TU651_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897607.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TU651_001635"
     CDS             7939..8865
                     /locus_tag="TU651_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897608.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TU651_001636"
     CDS             8874..9944
                     /locus_tag="TU651_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897609.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TU651_001637"
     CDS             9937..10860
                     /locus_tag="TU651_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897610.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3259 a         2145 c         2282 g         3310 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagcat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctatttacaa
    10981 aaaacctgtc aaaacc
//
LOCUS       DARYLD010000064        10955 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYLD010000064 DARYLD010000000
VERSION     DARYLD010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10955
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..793
                     /locus_tag="TU651_001638"
     CDS             <1..793
                     /locus_tag="TU651_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL0897611.1"
                     /translation="RLKECYPQLSFAEPMISSTMALESIKLSARVSLFKTIKNVSAIK
                     KSFYPCNMEELDQPTGYLLYRTHLARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEE
                     IGQDILIHQEGETTQLDILVENMGRVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHF
                     PLDFQELDWIDFSAGWTDEVPGFYAYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRF
                     WKVGPTLSLYIPKGLLKQGQNRLLIFETEGQFSESIRLTKEPIYK"
     gene            811..1296
                     /locus_tag="TU651_001639"
     CDS             811..1296
                     /locus_tag="TU651_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL0897612.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            1342..2223
                     /locus_tag="TU651_001640"
     CDS             1342..2223
                     /locus_tag="TU651_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL0897613.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            2210..3028
                     /locus_tag="TU651_001641"
     CDS             2210..3028
                     /locus_tag="TU651_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL0897614.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            3032..3436
                     /locus_tag="TU651_001642"
     CDS             3032..3436
                     /locus_tag="TU651_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL0897615.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(3540..3800)
                     /locus_tag="TU651_001643"
     CDS             complement(3540..3800)
                     /locus_tag="TU651_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL0897616.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(3925..4857)
                     /locus_tag="TU651_001644"
     CDS             complement(3925..4857)
                     /locus_tag="TU651_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL0897617.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(4867..5295)
                     /locus_tag="TU651_001645"
     CDS             complement(4867..5295)
                     /locus_tag="TU651_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL0897618.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            5553..6578
                     /locus_tag="TU651_001646"
     CDS             5553..6578
                     /locus_tag="TU651_001646"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL0897619.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            6639..7085
                     /locus_tag="TU651_001647"
     CDS             6639..7085
                     /locus_tag="TU651_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL0897620.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            7414..7707
                     /locus_tag="TU651_001648"
     CDS             7414..7707
                     /locus_tag="TU651_001648"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL0897621.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            7688..8920
                     /locus_tag="TU651_001649"
     CDS             7688..8920
                     /locus_tag="TU651_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL0897622.1"
                     /translation="MMMKPIKNNQDISIGDNVYLAFAALLVGVVVGVIDTVFGQGLLL
                     LSAVRDAHLIYLLPCLALAGLVIVFLYEQYGQIAKQGMGLVFDVGHGEKTRLPLVLIP
                     LIILSTWLTHLCGGSAGREGVAVQIGATVSHFFGRLRHLKDKSQLFLVMGMAAGFAGL
                     FQTPMTAVVFALEVLLLGNISYLALLPSLIAAFTASWTSHCLGLEKFSVPIAKALKIT
                     PITFGKLVLLGLIFGLAGNLFASLLARAKPYIAARLPNPYYRVLLVGGFLSLSLLLCH
                     YGRYSGLGTNLITAAFSHQPIANYDWLLKLLFTIITLSAGFQGGEVTPLFAIGAALGI
                     VLAPWLGLPAQLAAALGYAAVFGSATNTFLAPIFVGLEVFGATNATAYFIVIAFAYMV
                     SRRHSIYTKQRVTTSIAS"
     gene            9066..9413
                     /gene="rplS"
                     /locus_tag="TU651_001650"
     CDS             9066..9413
                     /gene="rplS"
                     /locus_tag="TU651_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL0897623.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9928..9999
                     /locus_tag="TU651_001651"
     tRNA            9928..9999
                     /locus_tag="TU651_001651"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9961..9963,aa:Arg,seq:cct)
     gene            complement(10123..10926)
                     /locus_tag="TU651_001652"
     CDS             complement(10123..10926)
                     /locus_tag="TU651_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL0897624.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
BASE COUNT         3013 a         2102 c         2514 g         3326 t
ORIGIN      
        1 acgtctcaag gagtgttacc ctcaattatc ctttgcagag ccaatgatca gttctacgat
       61 ggccttagag tctatcaagt tgtcggcaag ggttagtctt tttaagacaa tcaaaaatgt
      121 aagcgctatc aagaaaagtt tttatccttg taatatggag gagctagatc aaccaacggg
      181 ctacctactg tatagaacgc acctcgctag acatagcaag gaggagcggc tcagggtcat
      241 tgatgctaga gaccgcattc agctcttttt agatgaaaag cacgtgaaaa cccagtatca
      301 ggaggaaatc ggtcaggata tactgataca tcaagagggt gagaccacac agcttgatat
      361 tttagtcgaa aatatgggac gtgtcagcta tgggtacaag ctgacagcac caagccaaca
      421 aaaaggatta ggcagaggct taatggctga cttgcatttt gtaggtgatt gggagcattt
      481 tccactagat tttcaagagc tggattggat tgatttttct gcaggttgga ccgatgaggt
      541 gccaggattt tacgcctatg attttgattg tcagcagccg gcagatacct accttgattt
      601 gagtcaattc ggaaaaggaa ttgcccttgt aaatggtgtt aacctaggac gtttttggaa
      661 ggtcggtcca acattatcgc tttatattcc taagggacta ttaaaacaag gtcaaaatag
      721 actgctgata tttgaaacag aagggcagtt tagtgagtca attcgtttaa ctaaggaacc
      781 aatttataaa tagataaaag gagaaaactt atgacaattg ttgcagcacg tattgacggc
      841 cggttaattc atggtcaggt agctaatcta tggacgacaa agctaaacat tagccgtatc
      901 atggtggtcg ataatgaggt gattagcaat gaccttgaaa aaacagcact gaagctagcc
      961 acacctagcg gtgttaaatt atctatctta tctgttgaaa aagcagccaa caatattttg
     1021 gaagggcgct atgattctca acgcttgttg atagtagcca gaaagccgga tagctttttg
     1081 gagctgattc aaaaaggggt tgctatttca gagttaaatg tcggcaatat gtcacagaca
     1141 ccggagactc gtccagtaac gcgttctatt aacgttgtag acgaggatat agaggcattc
     1201 aaggctattt cagccaaagg gtgtcatctc attgcccaaa tggtgcctaa tgatgcccca
     1261 gcagacttta tgccgctgtt ggataaggtt gattaagatg tgtcaaatca aaaacgaatc
     1321 tgtttcagga ggtaaaagct tatgattcaa tggtggcaaa tcctattatt aacactctac
     1381 tcagcttatc aaatattaga tgagctaaca attgtctctt ctgcaggctc acctgtattt
     1441 gcaggattta tttcaggtat catcatggga gatgtgcaaa ccggtctttg gattggtggt
     1501 agccttcaat tgatggtgct tggtgttggg acctttggag gagcttcgcg tatcgatgca
     1561 acctctggtg cggttattgc gacagccttc tcggttgctc aaggcataga gccagaatta
     1621 gcgatttcaa ccattgcagt tccggtagcg gccttgctgg tttatactga tattctagga
     1681 cgcttttcaa cgaccttctt tgctcaccgt attgaccgcc atgttgaaaa ctttaactac
     1741 cgaggcatcg agcgtgatta ccttatggga gctgtacctt gggccctatc acgtgctctg
     1801 ccggtatttt tagcggtctc tttaggtggt ggtgcggttg atacagttgt taagttcatt
     1861 gaccattatg aatggctagc aaatggtcta actcttgcag gaaaaatgct tccaggcttg
     1921 ggctttgcga tcttgcttca ctacctacca gttaaacgta atctccatta tctggcttta
     1981 ggttttggct tgacagcaat gctaacaacc atttacacca accttcaggt agctggaggc
     2041 gcccttgcag gagtagccaa ggatttcaat gccgcaccat tcaaggggct gccaatgatt
     2101 ggtattgcta ttattgggct ttccttggca accctccatt ataaaaatgg tcaacaagca
     2161 cctgtagctg aacaaaaacc tggggtatca gaaagtgggg aaattgaaga tgacgaaatc
     2221 taattataaa ttaaccaaac aggattttaa tcaaatcaat aagcgcagcc tgttcacatt
     2281 ccaatggggc tggaactacg agcgtatgca gggctctagc tatctttaca tgattttacc
     2341 acagcttcgt aagatttatg gcgatggaac tccagagcta aaagaaatga tgaagacgca
     2401 cacgcagttt tttaacacat caaatttctt tcatacgatt atcacaggaa ttgacttggc
     2461 gttggaggaa aatgaaggac ttgcctcaaa agatgctgtt aatgggatta aaacaggctt
     2521 aatggggcca tttgctccaa ttggtgattc ggtctttggc tccttagtac cagctattat
     2581 gggctctata gccgcaggtc ttgctaaaga aggggtttgg tcagggatta ctggtgtatt
     2641 gatgtgggta tgtactcaga tgatcatcaa tgtgtttcgt tggaagcagc ttgaaattgc
     2701 ttataaagaa ggtacaaagc tcgtcaccac catgcgtgat aagctaactg ctgtagtaga
     2761 tgcagcctca gtcatgggag tattcatggt aggggcctta attgcaacaa tgattaattt
     2821 tcagtttacc gcagcaccca aaattggaga gaaagttatc aatattcaag atttaattga
     2881 taccattttt ccacgtctag ttccagcctt atttaccgga ggtatcttct ggctgctagg
     2941 gcgtaagggc atgtcaccaa ctaaggcaat tgttgtgatt attttatttg ccttagtgat
     3001 gtcttatttc aatattttag gagtatagct gatggcgcaa accttaattc tcattagtca
     3061 tggagctttt tgtcgagagc taaaacagag tacagaaatg attatggggc cacaggacaa
     3121 tattttaaca gcagagctgc aaccaaacga aggtgccgat gactttaaag aaaagctttt
     3181 aaggctaatt gcaggtttag atgacgtcct tgtgtttgca gatttgatgg gtggaacacc
     3241 ctgtaacgtt gccagtcgtt tgttaatgga aggacatcag tttgagctgt acgcaggcat
     3301 gaatatgcca atggtcattg gtttcattaa tgcctgtttg atcggtgaag cgtttgattt
     3361 caaagccttt gcctgtgaca atattcacca tgtcaatacc attatttcag ctctagcaga
     3421 tgatgatgac gactaaccaa gctcgcttat ttgtcacgca ccttacggag cgaaacggac
     3481 caagagccgc ataatcaaaa aagacactgc caaatcttgg cagtgtcttt gctgtaagct
     3541 tattttgctg cgtttgcgtc tttgagaccg tatttcttgt tgaaacgatc cacacgtcca
     3601 tcggcttgtg taaacttttg acgacctgtg tagaatgggt gtgagtctga tgaaatttct
     3661 acacgaacaa gagggtaagt ttccccttca aactcaatgg tttctttaga ggtcttagtt
     3721 gaaccgctaa ggaatttgta gcctgtagtt gtatcaagga aaacaactgg acgataatct
     3781 ggatgaatgt cttttctcat cttaaaaaag ttcctttctg ccatgatact gtccgtatca
     3841 tagttattaa ctactctagt ttaacaaaag ttagtaagct tgacaagctt tttctatcac
     3901 tattcatcaa taagatgata agtcttatgt taagagatca atcagctctt ggtagatttg
     3961 ctcattttcc tctaagcctg atgacgtggc accgctagca agagggtgcc cgcctccttg
     4021 atgacgctta gcaataccat tgatgacctt ttctttactg cgcatgcgta ctcggtactg
     4081 gccatctggc agctcaacaa agataaccca agcctgcacc acgtctattt ttccaggagc
     4141 agagacaatc gctgagcttt ctgccaagct aataccaaag gaatttagga cctcctggct
     4201 aagcagtagg cgggctgcac cactgtcatc tatatcaagc tgctcaaaaa catagccttg
     4261 tagcttggca attttaagtg gaaaggaatc catctgcctc gaaatagcag caaagtcaaa
     4321 ggcataattt cttaattggc ttgcaatggc cagtgtttta ctgcttgttg aggcatagag
     4381 aaagcgtcct gtatctccca caatgccagt atataatagt ctagctgcct catcagttaa
     4441 agccaagcct tggctaaagg caaattcagc aataatctca ctagcacttg aggtcttggt
     4501 gtcaacgtag gagagatcac catagacatc atcgttaggg tgatgatcaa ttttaatgag
     4561 gcaagcgccc attgtgtagc gctcatcatc aatgcggggg cgattggcag tgtctgtaac
     4621 aatcactaaa gcttccttat aatcatcgtc ggacacctga tccatgagac taatccaagc
     4681 cagactaggc tcatcaaagc ctgttatcag gacctttttg tcagggaaat tatgcctgat
     4741 aatctcttta agtcctgctt ggctccctag agcatctgga tcggggtttt ggtgccgatg
     4801 aatgatgatg gtttgatagt gcttaatgtg ttctaaaata gtttgaaacg ttgtcatagg
     4861 tatcctttag tttttgatca tatcaatgtg aggaatattg tcttccagat aaatctcaga
     4921 gactgcttta aacccaaatg agctgtaaaa aggctcaaga taagcctgcg cttgagcgta
     4981 gacgggaagc tttggaaagt gctgttgaca ataggctaag gcttgatgaa ctaagtcacg
     5041 tcctagtcct gttcgccttg cattttgtgc taccagtact cgtcccagct ttatgctatt
     5101 gtcagttggg attaagcgac agtaggccct aagctctgaa tcaacctgct tgaaaagatg
     5161 gatagctttt tgatccaaat cgtcaatatc aggataggga cattgctgct caaccacaaa
     5221 aacagccaca cgctctttat agatggcaaa caattcatct tttgttaact gatcaaatgc
     5281 tttaacaacc cacattagct agcctccaaa atcactggta caatttcctt tatgataaca
     5341 taatagcata tatcagccat aatggaacga aaaaaacctg actcttaatg gacgatgtcg
     5401 tgatgataat tacatcttgt ctcaaaagct ggtaatcatc acaggcacag aaaaatgtgc
     5461 cccttctgtt gctttttgag aaaaagttca cttgcttttt ggtagttttt tggtatcata
     5521 ctaaaaaata gacttaatta aggagataca gcttggaaac aaaagattta aagaagcttg
     5581 ctaaagctga gctgcactgc catttagacg gttctttgtc attagacact attcgtcagt
     5641 tggcggcttt ggcgcaggta gatgttcctc aagatgattc tgagttaaag cagctggtaa
     5701 ccgcaccgga aacctgtgaa tccttgatgg attatttaaa aacctttgat gttatcagac
     5761 cattattaca aacgcctcag gctttaacat tggctgctta tgatgttgtg aagcaggctg
     5821 cccttgaaaa tgtcatctac attgaaattc gatttgctcc tgagttgtca atggatcagg
     5881 gcttgaccgc cactcaggtg gtagaggcag ttttaaaagg actcgagcaa ggacaaaaag
     5941 agtttggcat tgtcgctaag gctattgtgt gtggcatgcg tcagtcctca ctagacatta
     6001 gcagagagat ttttgcaaat gtcttagagt gggccaataa aggcttggta ggctttgatt
     6061 ttgcaggcaa cgagctggac tttcctccag ctgtcttagc agatttgatc aaagagacgc
     6121 aggcctatgg gttaccattt acgcttcatg ctggtgagtg tggctgtcca aactatattg
     6181 ttgatgctat tgatttaggt atcaaacgct tagggcatgt gacggccatt cataaccaaa
     6241 aggatttatt ggccaagttt atcgccaatg atgtgacagc agagctgtgc ttcactagta
     6301 atctacaaac caaggctgct aggactgttg aggactttcc ttatatgcag ctaaggcagg
     6361 ctggcgctaa attatccatt aacacagaca atcgaacagt atccgatacc aatctgacaa
     6421 aggaatatga actgtttgtc aagcactttg agacaagcgt cacagacttt ttagagcata
     6481 atcgtgatgc tattaaggct agttttgcca gtccggctga aaaagaagct ttattggatc
     6541 gtttggaaaa ggcttatcag tcttacatca agaaataatg cttttcttgg caaagtatga
     6601 taaaatatac tgacatttag ttattttggg aggaaattat ggcattagcc aaaatcgttt
     6661 atgccagcat gacaggaaat actgaagaaa ttgctgatat tgttgctaat aaattgcaag
     6721 aattgggaca tgatgttgag gttgacgagt gtacaacagt tgatgcttca gagcttgagg
     6781 ctgctgatat ggcaatcgtt gcgacctata cctatggtga tggggactta ccagatgaga
     6841 ttgtcgactt ttatgaggac ttgcaggatt tggatttgtc aggcaagatc tacggtgtcg
     6901 tgggctctgg tgataccttt tatgattatt tctgcaaatc agttgatgat tttgacgaac
     6961 agctcgctgc cactggtgcc actaagggag ctgactcggt taaggttgat ttagctgctg
     7021 aggaagagga tattgctcgc ctagaatcct ttgctgagca aatgtcacag gcattagagg
     7081 cataagtaag acttttgata cagattggta aaacggtcag tggaggcttg cgttttttac
     7141 caccaaatgc atgaaaaact gatattttct gatcgttttt tcatgactat gtgctctttt
     7201 tcaagaaaag tcatgccatt attagcctga atgcaaacaa ttgatagtgt caaaatgttg
     7261 atcatatagt aaaaaaatgc atgtgactag aaagcagtta catgcatttt cgtcatgcgt
     7321 ttgtcgtgag gcattttggg ggttacttgc ttactgagct gaaattcact ataataaaaa
     7381 gataaataaa gaaaagaaga agttaggtga atgatgggat tagagaccat acgacaagac
     7441 attaatgctg ttgatcgtca gttgattgct ttgctggaaa agagaatggt cttggctgac
     7501 caagtagcgg cctataagca ggtacatgat gtgccagtgc ttgatcaaga gcgagaggct
     7561 gaggtcctaa ggagcgtgtc acagcagatt cggcataagg cctttgagcc tgccattctt
     7621 gagctattta agacaattat ggcagtatca aggcgttatc aggctgagca aatagcggtt
     7681 ggttcaaatg atgatgaagc ctattaaaaa caatcaagac atcagtatag gtgataatgt
     7741 ctatttggct tttgcagccc tgctcgttgg ggtggtggta ggtgtgatag atactgtttt
     7801 tggacaaggc ttgttgctct tgtctgctgt tcgtgatgct catctcattt acctgttacc
     7861 ctgcttagct cttgctggac ttgtgattgt gttcttatat gagcaatatg gccaaatcgc
     7921 taagcagggg atgggcttag tttttgatgt ggggcatggt gaaaaaacaa gactaccact
     7981 ggtgttgatt ccgttgatta tcctctcaac ctggctgacg catttatgtg gaggcagtgc
     8041 tggtcgtgaa ggcgtagcgg ttcaaattgg agcgacagtg tcacattttt ttggacgtct
     8101 tagacatctt aaggacaagt cacagctgtt tttagtcatg ggaatggccg caggctttgc
     8161 gggcttattt caaacgccaa tgacagcggt tgtttttgcc ttagaggtcc tgttgctagg
     8221 aaatataagc tatttagcct tgctaccttc tcttatagca gcctttaccg cctcttggac
     8281 ctctcattgc ctaggcttag aaaaattttc agtcccgata gccaaggcct tgaaaatcac
     8341 cccgataacc tttgggaaat tagtgctact aggccttatt tttggcttgg ctggtaatct
     8401 ttttgcctcc ttgttagcaa gggctaagcc atacattgca gcaaggctgc caaatcctta
     8461 ttatcgtgtg ttgcttgttg gtggttttct atcgcttagc ctgctgctgt gccattacgg
     8521 gcgctatagt ggcctaggga ctaacttaat tacagcggcc tttagtcatc agcctattgc
     8581 taattatgat tggctattaa agctcttgtt taccattatc actctctcgg ctggctttca
     8641 gggcggtgag gtcactccac tttttgctat tggtgcggct ttaggaattg tcctagcacc
     8701 atggcttggc ttgccggctc agttggctgc agcccttggc tatgctgcgg tatttggcag
     8761 tgccaccaat acctttttag ccccgatatt tgttggatta gaggtttttg gtgcaacaaa
     8821 cgcaactgct tactttatcg tgatagcctt tgcttatatg gtgagccgaa ggcattcaat
     8881 ctacactaag caaagggtga ccactagcat cgcttcctag tgtcttggtc agttttttgg
     8941 agaaaatagc tttacaagtg gggcttattt tgttacaata ggctccgtgt gtaatggacg
     9001 cacaaaaatt acggctaatc cgctaagact cgcgcttaag attagtaaga taaggagaat
     9061 aaacaatgaa tccattaatt caaagcttga cagagggtca acttcgtact gatattccta
     9121 gcttccgtcc tggtgacact gttcgtgtgc acgcaaaggt tgtcgaagga tctcgtgaac
     9181 gtatccagat ctttgaggga gtagtcattt cacgtaaaag tcaaggtatc tcagagatgt
     9241 atactgttcg taagatttct agtggtatcg gtgtagagcg taccttccca attcacacac
     9301 cacgtgttga aaagattgag gttgtgcgtc atggtaaggt tcgtcgtgct aagctttact
     9361 acctacgtgc cttgcaaggt aaggcagcgc gtatcaagga aattcgtcgc taaaaagagc
     9421 atacgagagg tttttcactg tcttatgaaa ggactgctgg agcagcaggg tctttgggac
     9481 aagctttttt tcgcaggtat gtgaacctac gctcaattca agacatatca aaggctcatt
     9541 ctatgataga gtgggctttt tgattgtgat catgctttag tgcctaaata aatgacagca
     9601 gcctgactaa tgaaaggctt acttgacttt ggaaatgctc aaggcttgcg ctaccagata
     9661 gaagctgaca tcatgccata gcagtcaagg ggaagaagga ctagattttt tggcgaggtg
     9721 ttgatctgtg accctgatgt tgttgggaat atgagagtaa tttaaaattt cgtcttgcat
     9781 tctacctttt tctaggttac aatagacaag taacctgatt agtgaagcta aaagacgtag
     9841 cgatgggttc taaaaaagaa tgattctggc gtttttggct aacctaagct gatagctttg
     9901 ctaggcagtg tcttagtcat ctggtcagtc ctgctagttt aacggataaa acaagcgcct
     9961 cctaagcgct agctgtgggt tcgattcccg cgcgggacat taaaaacaaa gtaaaaagag
    10021 tctgagaagg tttgagctgc ccctaattgt tagatttttt tctaactctt gaagtgtggg
    10081 tcaaagacta tttgtctcag gactcttttt aattggtttt tactaagctg cttcatctag
    10141 ttcttcagtt gctaagttgt ttccttcttc tgtatgttgg ttttcatcaa gtagcattcc
    10201 tgtgcggtaa tctaatgctg ccaaaggtga tacattatcc agaacaactg aggttatacc
    10261 ataatgatca acggattctt tgttgcctcc caatttgatt tggaggagct ctccgttttg
    10321 atcaattcca acgtactgta acactacttg acgaggaact aattcatcat tctgataaat
    10381 aggagttacc ttataatcta gccaaaagtt agggtgtatg gctaaccaat tgtctagtct
    10441 attttcataa taaagcattc ctaaaggatt tttatcacta aaacctgtat taaggtattt
    10501 tgtcatagta actaaatttt tgggttcatc atttaggccg ctaaactgat aaccgactag
    10561 atgtccgcga tccattaacc aagtcttttt ccctctagaa ttaatgactt gatagttatg
    10621 ccagccggga ggattaaatc taagcgcttt tcttttgaga gttggttcat cttgatcttt
    10681 gagttgtatg tgtgcatagg tggctctttg taaatgatca agatctccca gagctatttg
    10741 gtattttcca gtaaacggta aaattcctgg tatttcggta gcttttgttc ccaatgatat
    10801 ttccgttgta tctgggaagg ttctaagttt tcttgcagat tgaacagagt tagctgtgaa
    10861 aatagtcaga atagttaaca aaacaattgt tagacttttc cagttacggc gacgtgattt
    10921 agacatatca atgccctcct ttttttgttt acgag
//
LOCUS       DARYLD010000065        10947 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYLD010000065 DARYLD010000000
VERSION     DARYLD010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10947
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            4..594
                     /locus_tag="TU651_001653"
     CDS             4..594
                     /locus_tag="TU651_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0897625.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            604..2166
                     /locus_tag="TU651_001654"
     CDS             604..2166
                     /locus_tag="TU651_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897626.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHQID
                     DTFIYDGDIDLS"
     gene            2549..3650
                     /gene="prfB"
                     /locus_tag="TU651_001655"
     CDS             join(2549..2620,2622..3650)
                     /gene="prfB"
                     /locus_tag="TU651_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL0897627.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3701..4393
                     /gene="ftsE"
                     /locus_tag="TU651_001656"
     CDS             3701..4393
                     /gene="ftsE"
                     /locus_tag="TU651_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL0897628.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4386..5315
                     /locus_tag="TU651_001657"
     CDS             4386..5315
                     /locus_tag="TU651_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897629.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5705..6346)
                     /locus_tag="TU651_001658"
     CDS             complement(5705..6346)
                     /locus_tag="TU651_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0897630.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6683..9154
                     /locus_tag="TU651_001659"
     CDS             6683..9154
                     /locus_tag="TU651_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL0897631.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9328..10494)
                     /locus_tag="TU651_001660"
     CDS             complement(9328..10494)
                     /locus_tag="TU651_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL0897632.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWNMYVDNRLKTGSWKPDTEANKEAIYK
                     THFKKYLGKTKMKDISRIEYENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDD
                     NPIDGITIGDSEIIPVNKRISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVA
                     IKIGNLTKLENGRYRILLDESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVES
                     KRIAKKYNRILSKEDYLFLTNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
     gene            complement(10672..10929)
                     /locus_tag="TU651_001661"
     CDS             complement(10672..10929)
                     /locus_tag="TU651_001661"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897633.1"
                     /translation="MDLDIIEHQLNINCDIALCILSNTSKSKSKNITFTDAIAAIMFL
                     IGILFCLVAISFLLKGKFLEFLVGLFFTLVLSIPAYLKFSK"
BASE COUNT         3102 a         2119 c         2389 g         3337 t
ORIGIN      
        1 gctttggaag ggatcacaaa gtcctatggc gccaagctga tccttaagga tttttcctat
       61 acctttgaac aggggaaaaa atatttgata aagggtgcca gtggtagagg taagtcgact
      121 ctgttacaca ttattaaggg aactgctgtt gactcaggta aaatagcgtt tatcaccaaa
      181 gacaatcact catttgaaag ctatcaagct aacattggca tggtgagtca ggcacctttt
      241 ctctttaatg gcaccttgga agagaatatc tgtctgaatc aggagttttc caaggagaat
      301 atccttgctg tcttggacca agttcacctg ttggaggaat taccagctgg tctaggcttt
      361 cagatagaaa ataatgggac caacatttcg ggcggccagc gagtgcgcat agaattggct
      421 cgatttttgc tacgtcagaa ggatatttta ttgcttgatg aggtcacagc agccttggac
      481 aaggacaatg ctcggcgagt aagggagctg attttttctc ttcctattac catcattgag
      541 gtggctcatc atgtggatca agctatagct tatgatgata tgatagaatt gtaggtgatt
      601 aagatgttta agtattttaa taaatatcta gtgacactaa cgcttgttgc atgtgcctta
      661 aacagtcttg tctttctgat tgaacccttg atcactagta agatttttga tttaacgttc
      721 ttaaataatc atcaagacac cttgtccttt ttaggctatg gtctgacctt atacgtggtc
      781 ttatattctg ttatgttcat tgctaatctt ctgatcaacc atatcatgac gattgggtgt
      841 ggtagaatca ggttgcgtct ctatcagaat ttaatcttaa attatcggga gatgagtcat
      901 gacaagaaaa tttctatgct gactcaagat gtagaatatt atctatggaa tcacatcagc
      961 cctagcattc ttctcgtatc acacgtgagt aatgtccttt tgctcagtgc ttacctgtta
     1021 tcaaaaaaca tgctaattgg tcttattttt attgcatgtg cttttgtatt tttagtggtt
     1081 cagcatgtga ttggtcaaaa ggcagagcaa aaaggtagtg agctggcagt agcgagacaa
     1141 aagctgcttg gcttattaag tgatgtggtt gcggggcatt cgacattaat tcaaaatcaa
     1201 gctctttttg ctagcctcaa acaggtaaaa aaacagtcag agcattatga gagctcacgt
     1261 caagcatttg agatatttag gtctttcttt accctattgg cacatctgat gctgtttatt
     1321 tctcaattct tgcccatttt tttaggctta gccttaacct tattaggtgt taagctgaga
     1381 acaactgatc ttattgccat gtttattgca gcaacgcgct tagaacagcc actcaaaaat
     1441 attgttgatg atatgtttag gcttaatggt gcaaaagcca ttgctaagca ttttgagaca
     1501 cttttagagc agcctattcc aaaataccag tcgcatgcta tgacaggtga tccttttgaa
     1561 tgcttagatg gtcatcatct ggcgaaatca tttgcaggta ggaccttatt ttccgatctc
     1621 tcttttcatt ttgagaaggg aaagaaatac ctgattaagg gatcaagtgg atctggtaaa
     1681 tccacactct ttaagcttat cttacaggag atgagtcctg atgaggggac actagatatg
     1741 gtattgactg gaggtcagac gactgataat tatcaccatc gcatagggct gattgcgcag
     1801 tcgccttatc tttttaacga tagcattcgg tataatttga ccttggggga ggcgttttct
     1861 gatgagttgc ttttagaaaa gctagaacag gttggcttga ctgatgaatt tgacgatatt
     1921 ttaaaccacc aaattgttaa taacggagaa aatatctcag gtggtcaaaa gacacgtctt
     1981 gaaatcgcaa gaagcctcat tagacaaaaa gatgttcttc tagcagatga agtgacggct
     2041 ccacttgatg tcaaaaatgc taaaactatc cgacagctac tatttagttt accggtaaca
     2101 gttattgaaa ttgctcatca gattgatgac acctttatct atgacggtga tattgattta
     2161 tcgtagaaaa tatcatcaca ttgcttagaa ataataattg atgcttatga aattgtcatt
     2221 cacacagtga atggcttttt cttaggctaa attttccatg tggagcttga tctgataggc
     2281 tatctgagaa aaaaagctaa caacagccat gttttttggg gctatgactg ttctaatacg
     2341 agctgcctct agctgctggt atataagagg tgacatgatt gtcacaattc gtcatcattt
     2401 tgtcgttaaa tttttacata gatttcttat gctagtcatg gcagagctcc ttaccctaaa
     2461 aagaagggaa tttagctgat gggaaatagc aattctaaag cctttatgat aaaatgaaaa
     2521 aagacactat aatagaagag gtaactgtat ggaagtggca gaaatgcgcc agcaaatagt
     2581 agaaaacaaa gagaagttga ctagcttcag gaggtctctt tgacttagag cgtttggagg
     2641 aggatatagc tctcttagaa aataagatga cagagcctga tttttggaat gataatatgg
     2701 cagctcaaaa aacctctcag gaattaaacg agctcaagct cacctatcaa acctttcatg
     2761 atatgcagga gctatctgat gagacagagc tttatttaga aatgcttgac gaggacgata
     2821 gcgtcaagga agagctagaa gcaagcctga ttaagctcag ccagatgcta gcaagctatg
     2881 aaatgacgct gcttttgtct gagccctatg atcatagcaa tgcaatccta gaaattcacc
     2941 caggttcagg tggcactgaa gcacaagact gggcagacat gctttttcgc atgtacactc
     3001 gctttggaaa tgccaagggc tttaaggtag aaactctgga ctatcaagca ggagacgagg
     3061 caggaattaa gtctgtgacc ctttctattg aagggccaaa tgcttatggc ttcttaaaat
     3121 cagaaatggg agtacatcgt ctggtgcgta tttctccttt tgactctgct aagcgtcgtc
     3181 acacctcctt tgtttcagtt gaagtcatgc cagagcttga tgataccatc gaggtggaga
     3241 tacgtgatga tgacattaag atggacacct tccgctcagg tggtgctggt gggcaaaatg
     3301 tcaacaaggt ctcaactggg gtacgcttga cccatatccc aacaggaatc gtagtggcgt
     3361 caacagttga ccgcacccaa tatggcaacc gtgatcgcgc tatgaaaatg cttcaagcca
     3421 agctttatca gttagagcag gagaaaaagg cagaagaggt caatgccctc aagggggata
     3481 aaaaggagat cacctggggc agtcagatca ggtcctatgt ctttacgcct tatacgatgg
     3541 tgaaggatca tcgtaccaat tttgaggtgg ctcaggttga taaggtgatg gacggagata
     3601 ttgagggttt tattgacgct tatctcaaat ggcgcatggg tgaggattaa agtgatcccc
     3661 actcagataa acactaacag cttagagaag gaagaataag atggcattaa ttgaaatgaa
     3721 gggtgtttct aagaaatacc gtcgctcgac aacagctctg agagacatta atgtctcagt
     3781 caatcaaggg gaatttgtct atattgttgg tccatcagga gctggtaaat caacctttat
     3841 caagcttctt tatcgcgaag aaaagctaag ctcaggcagc ctaaaggtgg gtgagtttga
     3901 cttaaccaag ctaagaggac gtgaggttcc aattttacgt cgcagcattg gtgttgtttt
     3961 tcaggattat aagttgctcc ctaaaaaaac ggtctttgaa aatgttgcct atgctatgga
     4021 ggttatcgga gagagacgtc gccatatcaa aaagcgtgtt cctgaggttc tagaccttgt
     4081 cgggttaaag cataagatgc gctcctttcc caatcaattg tcaggtggtg agcagcagcg
     4141 tgttgcgatt gcacgcgcta ttgtgaacaa tcccaagctc ctcattgcag atgagcctac
     4201 aggcaatttg gatccggaaa tttcttggga aatcatgcac ctgcttgagc gtatcaatct
     4261 acaggggaca acgatattaa tggcaacgca taacagtcat atcgttaata ctcttcgcca
     4321 tcgcgtggtt gcgattgaaa atgggcgtat tgtccgcgat gaggagaaag gagactatgg
     4381 ttacgatgat tagacatttt ttccgtcata tctgggaatc tatcaaaaat ttaaggcgta
     4441 atctcctcat gacctttgcg tcagtcagta tggtgaccgt caccttaacc ctgcttgggg
     4501 tctttgctgc aaccctgctg aacattcaac gtgtcgcttc tggcgtggaa aacaacattc
     4561 aaatcaatgc ttacttacag gttgattcga cagatgctgc taagatggtt cagtcgatta
     4621 atggagagca gataaataac gagaattacc ataagattta tgatcagatt gcagggctaa
     4681 agggtgttga gaggattatt ttctcaagca aggacgagca gctgcaaaag ctacaggata
     4741 gtctgggcga tgtctggggc atgtataatg aggatagtaa tcctctgcaa gacatctata
     4801 tcgtagagac caagacccct aagcaggtca aatcagttac caaggccatc aaaaagattc
     4861 aagggattga agatgcggac tatggtggta ttaattctga taagcttttt aagttttcaa
     4921 aactgattca aacatggggg attatcggaa cgctgttgct cctgtttatt gcgatctttc
     4981 tgatttcaaa taccattcgc atgaccatca tgtctcgtca gcgcgatatt gcgatcatgc
     5041 gtctggttgg tgcgaaaaat tcttatattc gtggcccatt cttttttgaa ggggcttggg
     5101 ttggtctgtt tggtgcgata ttgccatcgt tgattattta ttatggctac gagtttgcct
     5161 acaagcattt caccccggaa ttacagcata atagcctgtc tatgtaccct atcaatccat
     5221 atgtttatta tttaattggc atgctttttg tgattggtat tatcattggg tcactaggat
     5281 cagtcttatc tatgagacgt taccttaagt tttaattgaa agagcttcta gcctgtgtgc
     5341 ctggactggt accctgcggt tagggctctt tttgcttttg gggcaatgct tgctagataa
     5401 gcaaacaata gcttaagccc ataccattaa gtattgggct taagctattg ttatagttgt
     5461 ttaggtaata gaagcagccg gaacttgagg tgtcctatct aggtcttgag ctatagcttt
     5521 tctggctagt tggtgtttct tcacgtaaca gcgatttgtc gaacgataag gtgctcttct
     5581 tgtgatagct ggcttgtagt gatcgacagg tgctaagtca aattagccat cctgatggac
     5641 tggagtcata gcttttgctg ctgcgcctgg ttgggcatag actgggcatc tcggtagctt
     5701 gagcttatcg ctgcctcaga aagggattgc tatttttttc atggctaatg gtggtagctg
     5761 agccatgccc cggataaatc tgataatggt taggaagtgt tagcagctta tcacgaatgc
     5821 tagcaagcag ctgttcaaga tttccagtcg gcaaatctgt tctaccgatg ctttctctaa
     5881 acagagcatc gccagtaaac accgcctcct cctgctcaaa gataaaggaa acgccaccgg
     5941 cagagtgtcc tggtgttggc actactgaaa agtgaaatcc agctagctga taaggtgtct
     6001 gatactgaaa gagcttttct gctggtttgc agatgatatc aggcagatca gcgtgacgta
     6061 tcagtcctga caggttcatt tctggtttat aaagccagtc cgcctcctcc ttggcaacat
     6121 agacaggagg gtgctggcag ctctctctca ccagctctag gctcataatg tgatcataat
     6181 gcgtatgggt cagtaggata gcagcaacag gcttgttgat ggcatggatt tgtgataaaa
     6241 tagcctgccc cttgcttcct gggtcaatga ctaaaatagc ctcgtcattg acaagaaggt
     6301 aagtgttttc acccgcaacg ggattcatca gtgtcataat agtcataccc ttagtttacc
     6361 aaaatctgac tcaaaagaca gctcaaaacc acctcttttg ataaaagtga tctgtttaat
     6421 ggttttgatg gctaagccaa gatagctcca gcttaaaggc tgcttttttt aattaatagg
     6481 agcaaaaagg agctgcctca gcgctaacag ctaatcagag tattagctct ctagtgtcat
     6541 agcaaggaag taggctgggg cgattaaaag gcttgataac tagcttttta tgatactgac
     6601 tagccctatt gagctgagct aagactggta ttgtcagatt taggcaaagc ctgtcagaaa
     6661 acgtgctata atagatagta ctatgatcaa tgagttttca caaaaatatg ctgtgattga
     6721 cctggaagcc actagcccag gtccaacagc gtctattatt caggttggca ttgtgatcgt
     6781 tgaaggaaaa gaaatcgttg attcgtatca aactgatatt aatcctcatg agcccttgtc
     6841 agaccatatc aaagcactca caggtattac agaccagcag ctagctcagg caccggattt
     6901 ttcacaggta gcaaggacca tttttgagct gattgaggac tgtgtttttg ttgctcataa
     6961 tgtcaccttt gacgccaatt tgttggcaga agccttattt ttggagggct atgatctcct
     7021 cactcctaga gtggatactg ttgagctggc tcagattttt taccccagcc tagaaaaata
     7081 cagccttagc cacctatcag aggtgctaga cctaaaccta tctgatgctc ataccgctat
     7141 tgctgatgct caggcgactg ctaacttatt tatcaagctg cttcacaaga tagagagctt
     7201 gccaagagaa tgcttggaga ctcttttgct gtatgctgat agtctgttat atgagacagc
     7261 tatgattgtg agacaagccc ttgcagtcag tcggccttat tctacgagtg actacatcaa
     7321 gattaatcag atcttgctaa aaaagccgga tcagctaaca aagccctatc aattatccca
     7381 gtcctttgag attaatgcag ccctcttagg tcttgaggag cgccccaagc agctcagctt
     7441 tgcaaagatt gttgaggaga ctctttttca gaccgagcca gcctttatcg aggctcaggc
     7501 aggcattggt aaaacctatg gctatttact gcctctcctt gcacagaaac atcagaccca
     7561 aatcttggtt agtgtgccaa ccaagctgct acaggaccaa atcatggcta atgaggtgag
     7621 ggctattcag gagcagtttc acatcgattg ccatagtatc aaggggcctg ctaattacat
     7681 caagctagac agctttcaag agagcctcaa tcagcttgat gacaaccgct tggttaatcg
     7741 ctataaaatg caattgctgg tttggctttt ggaaacaagg actggtgatt tagatgaaat
     7801 caagcaaaag caacggtttg cagcttactt tgaccagatc aagcatgatg gcagtatcca
     7861 gcagacctcg cccttttacg cttatgattt ttggcaacaa agctatcaaa gggctaagtc
     7921 agctcgcttg ctgatcacca atcatgccta ttttttacac cggattcagg acgataaggc
     7981 atttgccaag ggtaagattc tagtctttga tgaagctcag gccttaatgc tgcagctaga
     8041 ggagctagct catcagcgac taaatatagc tgatacgctc caagagcttc aagagcagct
     8101 agctgtgcca agcagcttgc ttgagcaacg cttgctagag ggcattgcct ttgagctcaa
     8161 tcagttaagc agtcattatc atcaggagga ggagaagcag caagctcaag cctcacagca
     8221 tttgctgcgg ctccaagagc atgtcaagga gctaggtgct gcagcctctc agagcctcaa
     8281 gcagctgttc aagcagcagg aaatggatta ttgggtgagc agtgagcagc aggctgacaa
     8341 gcgccaaacc tttttaaatg gcagcagcag gacggtcctt cagtttaaag cattgctacc
     8401 ggagattttt aaggcctact ttgtctcagc tactctacag attagcccta gcattagctt
     8461 ggctgattta ttgggctttg acacttattc ttatcatcag ctggctaagg agaaaagcac
     8521 tcagcaattg gttgtcattg accaagacat gcccttgatt aaggacttga ctgacgaggc
     8581 ttacacacag accatagcag caaggctatt agtgcttcat cagcaacagc aggtacctat
     8641 cttagtgctc tttaatgcta aaaagcacat gctcatggtt tctgactatt tagaggctaa
     8701 tcaggtgcag cacttgacac aaggcaaaaa cggtacagcc tatcacatca aaaagcgctt
     8761 tgatcgtggt gagcaatcaa tgctgctggg gcttgcagcc ttttgggagg gagttgactt
     8821 tgttcatgct gatcgcatga tagaggtcat tacccgcctg ccctttgata atccagaaga
     8881 tattgccact caaaaaatgc agcgctacct acaggcagca ggtaagcagc cctttaatga
     8941 ttattttctg ccgatgacga tcttaagatt aaagcaggcg attggtcgaa ccctgcgtcg
     9001 aaaagagcag aaatcagcag ttttgatctt agatcgtcgc attctgacca tgtcctatgg
     9061 tcagaccatt ttgcacagcc tagaagagga atttctgata tcacaacaaa atttccaaga
     9121 tagtctagca gaaataggcg attttttgat ataatgaaaa atagtaattt ttatttagtt
     9181 attttaattt atttattttg caaatgttta tttataggca tttgcttttt tgtttaattg
     9241 ataccaaata ataaaaatct ataaattgtc ggggaatata tcgggggatt tgttaattta
     9301 agcatttgta taaatttccc cgactaacta gtttaaagcg ctcataaatc tatcagtaac
     9361 actaccagca acctcctcct ttatgtgagt atatttgcta gtcatgtaac ttgtagaatg
     9421 acctagtgct gcggccatat gttcaattgg gacacctgct atctgccctt gggtggcgaa
     9481 aaagtggcgc atcatgtgtg gggtaacatg cataccagat ttttcattga cagtattaaa
     9541 aagtttatag actcgcctaa tagagatcgg cattcctaaa agttcttttt tcgcattctt
     9601 aaagttagtc aaaaataggt aatcctcttt tgataatata cgattatact tctttgcaat
     9661 ccttttagac tcaacaacaa catcatcaat ataatgcgat gtttcaagat caacttccat
     9721 aaaccgctct gatcctggcg ttttcattcc tccaccgttt ggacgatggt acgtcctaga
     9781 ctcatctagc aatattcgat atctaccatt ttcaagcttt gttaaattgc caatttttat
     9841 ggcaacaact tcgctactac gagctccgaa gtaagtcata cggacaatag tataatcgta
     9901 ttgaatcaat gacttcttgg cccatgaatc ccactctttg aattcttcaa gcgatattct
     9961 tttgttaacg ggtataatct cactatcgcc aatagttatc ccatcaattg gattgtcatc
    10021 tagcatttta ttggtgactg catgattaag cattgcgttg agtactgaat ggatcaagcg
    10081 taaagtgttc tttgaataat tcttacgcat accattaata tgattttcat actcaattct
    10141 agaaatatct ttcattttag tcttgcctaa atattttttg aagtgagttt tgtatatagc
    10201 ttctttattt gcttcggtat caggtttcca tgatccggtc tttaggcgat tatctacata
    10261 catattccag tactgatcaa ctgtcaaatt tttgttataa gcaaaatcat tgttttctat
    10321 tttttgctca atttcagtaa gtgcagctct ggcttcctgt agcgttttta agttgctttt
    10381 tgtagcctct ttctttttac cttttaagta ataaccccta cggacgtagt agcgtttacc
    10441 tttctttgta tcgtaggtaa agatatttgg gtattttgtt ttgttgtatt tcattttaaa
    10501 atcctttcat gtattttgac ttttggacga ggtcgtttga aaggatattg gcatcacctc
    10561 ctttgtgtga tataattagg tataataaaa cgcccttttt aatggttgtt ttatattttg
    10621 tgtagtctcc acgttgcgct ttggtcggtt gtaacgtggg gcttttttgt tttatttact
    10681 aaattttaaa tatgctggta ttgataaaac taatgtaaaa aacaacccaa ctaagaactc
    10741 taagaattta cccttaagca aaaaacttat agctactaag cagaataaga taccaattaa
    10801 aaacattatt gctgcaattg catctgtaaa tgtaatattt ttagatttgc tttttgatgt
    10861 attcgacaaa atacagagtg caatatcaca gttaatattt aattgatgtt cgatgatatc
    10921 taaatccata tcaatcgttt tatatgg
//
LOCUS       DARYLD010000066        10899 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYLD010000066 DARYLD010000000
VERSION     DARYLD010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10899
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            215..952
                     /locus_tag="TU651_001662"
     CDS             215..952
                     /locus_tag="TU651_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL0897634.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            991..1491
                     /locus_tag="TU651_001663"
     CDS             991..1491
                     /locus_tag="TU651_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL0897635.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            1510..2199
                     /locus_tag="TU651_001664"
     CDS             1510..2199
                     /locus_tag="TU651_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL0897636.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            2593..2835
                     /locus_tag="TU651_001665"
     CDS             2593..2835
                     /locus_tag="TU651_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL0897637.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            3015..3809
                     /gene="racE"
                     /locus_tag="TU651_001666"
     CDS             3015..3809
                     /gene="racE"
                     /locus_tag="TU651_001666"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL0897638.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            3806..4795
                     /locus_tag="TU651_001667"
     CDS             3806..4795
                     /locus_tag="TU651_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL0897639.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            4771..5292
                     /locus_tag="TU651_001668"
     CDS             4771..5292
                     /locus_tag="TU651_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL0897640.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            5289..5750
                     /locus_tag="TU651_001669"
     CDS             5289..5750
                     /locus_tag="TU651_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL0897641.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            5747..6493
                     /gene="xerD"
                     /locus_tag="TU651_001670"
     CDS             5747..6493
                     /gene="xerD"
                     /locus_tag="TU651_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL0897642.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            6493..7200
                     /locus_tag="TU651_001671"
     CDS             6493..7200
                     /locus_tag="TU651_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL0897643.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            7197..7736
                     /locus_tag="TU651_001672"
     CDS             7197..7736
                     /locus_tag="TU651_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL0897644.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            7973..8695
                     /locus_tag="TU651_001673"
     CDS             7973..8695
                     /locus_tag="TU651_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL0897645.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            8692..8970
                     /gene="yidD"
                     /locus_tag="TU651_001674"
     CDS             8692..8970
                     /gene="yidD"
                     /locus_tag="TU651_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL0897646.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            9129..9677
                     /locus_tag="TU651_001675"
     CDS             9129..9677
                     /locus_tag="TU651_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL0897647.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
     gene            10056..10487
                     /locus_tag="TU651_001676"
     CDS             10056..10487
                     /locus_tag="TU651_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897648.1"
                     /translation="MVVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            10488..10778
                     /locus_tag="TU651_001677"
     CDS             10488..10778
                     /locus_tag="TU651_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897649.1"
                     /translation="MITDKNYNWLAGKVYDVDANKVTIPVRKNTDILNRYVKVLEAED
                     NPDNGMQFTVSKSNRNVLALNYKLRSFYDSKKESHHFIRNGSNFSNGRYIYV"
BASE COUNT         3170 a         2010 c         2536 g         3183 t
ORIGIN      
        1 ataggcaaag actgcaagtg ggctatctgc tgaggtaaac aataggtctt agtgcagcaa
       61 ggctatgttt atggttagct ctccttcttg tcttctaaaa aggaaagcta atgggcttac
      121 gacacctgat aaggggagaa agctcctttt aggctgatag ccttctgatg gtttttatgc
      181 aaaagagtga acaattttgt gatataataa gaccatgatt atcacatcaa aagcaaacca
      241 tttgattaag caggctaaga aattactgca aaaaaagcat cgcaagcact cttacttgat
      301 tgagggctgg cacctatttg aggaggctca gagatctggg caggaattga tacatatttt
      361 tgttctggag gaaatggcag agcgcttatc aggctttgat caggttgtca tcgtcagtcc
      421 agagattcta aaggagctga cgagctctcc caatccacag ggcattattg ctgaggttaa
      481 gctttgtcaa caggccttac cgactagcta tgctggaaaa tatttgattt tagaggacat
      541 tcaggatcca ggcaatctag ggacaatcat tagaacagcg gacgcagcaa agtttgatgg
      601 ggtgtttttg tctgagaagt ctgcggatgt ctacaatcaa aaaactctac gctccatgca
      661 gggcagtcat tttcacctgc cgatttggcg aacggatatt tatcaggtca gtcaggtgat
      721 gcagcagcaa aaaataccag tgctagcaac gaccttgtct caggattcga ttgattacaa
      781 ggacctctca gctaggagca gccttgccct tgttttagga aatgaaggtc agggcattag
      841 tcctgagatg gcagctttgg ctgatcagct gattcatatt agcatgcctg gacaagctga
      901 aagcttaaat gttgcagttg cagcaggaat cctcattttc agcctaattt aagctagtat
      961 ggtataataa tgatgtgagg tgattagtgt atgcattata cagaagatac agaatacatg
     1021 gagcatgttg gtcatttgat tgctcaccct cgctttcaaa ggcttggaga tattgttcag
     1081 catcaccatt ctactcgctt agagcactct gtcaatgttt cttattctag ctataggctg
     1141 gcaaagaggc ttggcttaga cgccaagagt accgcacgag gtggcttgct acacgatttc
     1201 ttttattatg attggcgagt aaccaagttt aacaagggac acgcttgggt gcaccctaga
     1261 attgctgttc gaaatgctaa aaaattaaca gcactcaaca aaaaagaaga ggatattatc
     1321 ctaaagcata tgtggggagc tactattgct tttcctcgct ataaggaaag ctatattgtt
     1381 acctttgttg ataaatattg ggcggtcaag gaggccatga cgccgctgcg tcaaaaatgg
     1441 acgaaccgtc gcttcctgcg tcgaaagacg cttcaaagtc acaatcatta agtaaaaaaa
     1501 ggagttatga tgaacgataa tgttatttac acacagtctg acgcaggctt gagccatttt
     1561 tttgccaagg tctatagcct ggttggtatg ggagttgggc tttctgcctt tgtttcttat
     1621 ttgatgctgt ttccatttag gcaaaattta gtctcgattg ttcttgatca tcctatggtc
     1681 tattatgggg cggctattgt tgagcttgta ctggtttttg ttgctagtgg tgctgcacgt
     1741 cgcaatacac cagcagcttt acccttattt cttgtctatt cagccttaaa tggctttacc
     1801 ttgagcttca ttattgcagc ttatgcgcaa acaacggtgc tacaggcctt tatctcatcg
     1861 gcagctgttt tctttgctat gtcactgctt ggtgttaagg ttaagcgtga tctgtcaggt
     1921 attcgaaagg ccatgtttgc agccttgatt gggattatcg tggctagtct ggtaaatctc
     1981 tttatcggta gtgacctgat gagctatgtg atcagcctta tttcagtgtt gatcttttct
     2041 ggcttgattg cttcagacaa tcagatgatc aagcaggtct accaagcctc taacggtcag
     2101 gttggtgacg gctgggctgt cgctatggct cttagcttat acctagactt tatcaacctc
     2161 tttatcagtc tacttcgtct cttgggaaga aatgactaat agctatttta agcgcagctg
     2221 ctgattgtca cttaatcgct attacgagaa atcagcgaag ctgcaggtgt taccttttgt
     2281 tagaaaagag tggctgctgc tagtaagaaa gtagctgcta ggagagcctg atgagcgtga
     2341 ctgtcaagga aggccagtta ctattgctac catctaggga aggtaccaaa aaaagtcaag
     2401 aagcgggccc aagggctcgt ttttgtttgc ttgatttgtg gtaaagtgct tcaaaccaag
     2461 cctatatcta gtctgatagc tcttatcagc tgacaacatc atatttacaa tgcctgttgg
     2521 tgtagatttg taaagcatgc tcttttttgg tataatgaga ggaacaaaaa atcgaggaga
     2581 atatctatca atatgtctac agctatctgg atattattaa tcattgttgc tcttacagcc
     2641 ggtctttttg gtgggatttt tattgcccgc aagcaaattg aaaaggaaat tggagagcac
     2701 ccacgattaa cgcctgaggc cattcgtgaa atgatgagtc aaatgggtca aaaaccaagt
     2761 gaagcgaaaa ttcaacaaac ttaccgcaac attgtcaagc aatcaaaagc cgcaatgact
     2821 aagggtaaaa aataggttac ggattagaaa tcgtggtttc taagcaatag ctaagagtga
     2881 acagtctttg atgttaaaag cttgtttaga gcttgcattg tcagttagag gtgtcaactg
     2941 ttcaggggtt aacaatagac tcagttggct cttaccagct gagtttttta tgcttcaatg
     3001 aggaaataat cgttatggac aatagaccaa ttggtttttt agattctggt gtaggaggct
     3061 taactgttgt tagtgagctg atgcgtcagc ttccccatga aaaaatcatt tatattggtg
     3121 attcagcaag agctccttat ggtcctagac ctgctgaaca aatcagagaa tatacctggg
     3181 agttggttcg ttttttatta acgaaacatg tcaagatgat tgtctttgct tgtaacactg
     3241 caacagctgt tgcttgggag gaggtcaagg aggctttgga tattcctgtt ttgggcgtta
     3301 tcctgccggg cgctagcgca gctatcaagg ctactagtgg aggaaaggtt ggtgttattg
     3361 gcacatcaat gactatttct tcaggcattt accaggaaaa gatccagttg ctggctccca
     3421 ctgttcaggt aactagccta gcctgtccta gatttgttcc tattgtggag tccaatgaga
     3481 taagctcaag tgtggccaag aaaattgtct atgaaacctt ggctccctta gttggaaaga
     3541 tagataccct tgttttgggc tgcacccatt atcctcttct taggacgatt atccaaaatg
     3601 tgctgggacc acaggttaaa ttgattgata gtggggcaga gtgtgtgcgt gatatttctg
     3661 ttcttttaaa ttattttgag attaatggca gtcgagatga tgaacatagg cgtcatcatt
     3721 tttacactac agccggctca gacagctttc aagcaattgc ctcagcctgg ctaaatcaaa
     3781 cgatagatgt ggagcatgtg accttatgag tgataacatt tatgaataca aggataaaga
     3841 caattggttt attggcaaga tgacaggcca taatttaatg gctggctggg gggttaacca
     3901 tgagcttatt gccaaaatag acgatatgtt aggtgcgatt gctggtgatg tggattggga
     3961 aagtccggtc ggttatgatg tgactgttat tcgttacgcc tccccttttg ccttgattag
     4021 ctttgttgtt ggcatgatca atcagaaagc caatcgagcc cttaaggttg ttcggcactc
     4081 aggtgcgatt ttagtgaccg aaaacgagcg attgcttgct gtgcatatgc cagatgatgg
     4141 cgtccctgtg gctgacttct ttggtcaaca ggcagatggc tttggggata cgattttgat
     4201 tgcgactcga aatgaaggca agaccaagga atttcgccgg ctttttggtg atatgggata
     4261 tcgcgttgaa aatctcaatg attacccaga gcttccagat gtggcagaaa ccggggtcac
     4321 ctttgaggaa aatgcccgcc taaaagcaga aaccatttca aggcttactg gaaagatggt
     4381 tctggcagat gattcagggc tcaaggtgga tattttaggt ggcttacctg gggtctggtc
     4441 agctcgtttt tcgggccctg atgctactga tgagactaat aatgctaagc tattgcatga
     4501 gctggcaatg gtatttgatc aaaaggatcg ctctgctcaa tttcatacga ccttggtggt
     4561 tgctgcacct ggtaaagaca gcttggttgt cgaggctgat tggcatggct atattgcaac
     4621 caagccaaaa ggcgagcatg gctttggcta tgatcccttg tttatcgttg gggagactgg
     4681 acgtcatgca gcagagctag ctgctgatga aaaaaacaag ctgtctcata ggggacaggc
     4741 ggtcaagagg ttaatggagg tatttccagc atggcaagca aaacaatcat tgtgatgagc
     4801 gattcgcatg gcgatcgtga ggttgtggca gctattaaag gccgttacct tggaaaggtt
     4861 gatgccattt tccataatgg cgattctgag ctagaaagct cagatcctat ttgggagggg
     4921 attcatgttg tggcaggcaa ctgtgaccat gatagcggct ataaggatag cctagtcacc
     4981 tcctttgatg gcttgactat tgctcaaaca catgggcatt tgtatcatat taactttact
     5041 tgggataggc tagattattt tgctcaggag actggagcgg atatttgttt gtatgggcac
     5101 ttgcacagac ctgctgcttg gcaattgggc aagactgtct ttatcaatcc tggctcggtc
     5161 gctcagccgc gtggtgaggt gaatgaaaag ctgtacgcgc gtgttgaatg gacagcagct
     5221 tgcattaggg tggattactt tacctgtcag cataagtctt acccatcact ttctaaggaa
     5281 tttaaacgat gatagcaaaa gaatttgaag cctttttaat cagtcatttg gatagctacc
     5341 tgattccagc agaggagcta gccattttta tcaacacgca taatgctgat catgtcatgc
     5401 tcttattggt tagcaatggt ttttcacgag ttcctgtcat taccaaggaa aagcaatatg
     5461 tcggaacgat cagcatttct gatataatga cctatcaagc caaaaggcag ctaacagact
     5521 gggagatgac gcaaactaat attggcgaca tggtcaatac aaagattgag accatcaata
     5581 ttacctctag cttgactgaa atcatgcata aattggttga ttttcccttt ttaccagttg
     5641 ttaatgatga caatcgattt atcggtatta ttacgcgtaa gtccattttg aaggcggtta
     5701 atagcctttt gcatgacttc actgatgaat acacaatcac aaaaaaatga tagcatttat
     5761 tgaacccttt ctagcaagca aatctcttgc taataacagc cagcaatcct atcgctatga
     5821 tttaaggcag ttttgccagc aggtcggaca gcgtattaat cctgaaaccc tagccctcta
     5881 tcagcaaagc ttgtctggcc ttacggtagc agctaaaaag cgcaagcttt caacggtcaa
     5941 tcagtttttg tactatttgt accagcagaa ggctttgaca gactatttta aaatggacga
     6001 taggatagaa gcctcttttt ctttgaagcc ccagctgaca aggcttgaca ccagcgcttt
     6061 ttatgctgaa acagccttcc taaaagggca gctcattgcg ctgctgattc tggagctggg
     6121 cttgacgcca agtgagatag cagggcttcg tcttgctgat tttgacctgg gtcttcaggt
     6181 gctaaggttg caatctcaca gaggcattcg tgtgatgacc ttatcaaagg ccttgctgcc
     6241 atttttggaa aaggcaacag aagctcagca gctctacctc tttgatcatg acgccaagcc
     6301 cttttcaagg caatggtttt ttaaccagct cagagatttt ttagagagca ttggctgtgc
     6361 ggagctttca gcccagagtc tgagagagca attcatttta aatgaaaaag cagccggtaa
     6421 atccatcatt gaggtggctc agctgctggg gctaaaaagc ccgatcacct tagaaaaata
     6481 ttataagatg taatggatat aaaagtaaaa gattttgaag gtcctcttga tttactcttg
     6541 cacctagtgt caaagtatga ggttgatgtt taccaggtgc ctattgtgga ggtcattgaa
     6601 caatacttgg cctatattga gaccctgcag gcgatgcgct tggagcttgc tggagagtac
     6661 atgctgatgg ctagtcagct gatgctcatc aaaagcagac gactgctgcc aaagctggta
     6721 gacaaggagc ctgatgagga ggatcttgag caagagcttt tgggtaagat tgaagaatat
     6781 agtcgtttca aggctctgag tcaggagttg gccagccagc atgacaagag ggctctgctt
     6841 ttttccaagc caaagcagga gcttatcttt gagcaggccg tcctacaaaa ggataaaaca
     6901 gtcatggatt tgtttttagc tttttcacag ttaatggctg caaagcaaga ggcctttaaa
     6961 tataaccata cggttattga gcgagatgat tatcgtattg aggatatgat ggagcttatt
     7021 gaagctaggc ttgagctaga gcaggagctt actttgacgg atttattgaa gcattgtgat
     7081 catctcaatg aggccattac cttgttttta gcaagcctag aattaatcaa acggcagctt
     7141 gttggtattg agcagacatc acattttggc cagattgttt tgcgaaagga gatccaatga
     7201 cctatttatc tcagctggag gccttgctgt ttgtcgcagg agaagaagga ctaagcctac
     7261 gtcagttggc cagcctatta gagttaacac cgacagcctt acagcagcag ctcgacaagc
     7321 tttctcagaa atacaaagag gataaggaat ctggcctgtg cttgattgag tcctctagga
     7381 cctataagtt agtcaccaaa gagtgtctgg ctcccttgct taaagactat gctaaggctc
     7441 caatcaacca aaccttgtca cgagcaagcc tggaggtttt gtcaattgtt gcctataagc
     7501 agccgattac tcggattgaa attgacgaga ttcgtggtgt caattcaagt ggtgccctta
     7561 gtaaattagt ggcctttggt ttggttcaag aggctggcaa aaaggaagtg attggtcgac
     7621 caaatcttta tgcaacaaca gattactttc ttgattatat gggtatcaat catttagaag
     7681 agctggttga tatttcttct attgctgttg aagagcaaga gacaaccctg ttttaaaggc
     7741 aaagaggagc ttgtctcatt tgcagatagg ccttatgccc tctactagaa gagataacag
     7801 tcctaacaag gtatagtgcc tgaaaatcct attgtcgtta tggacagcgg tctttttagg
     7861 catgctatta ataagagtag acctgtttaa gctagtgagc ttttacccat aggagagtga
     7921 ctggtctgtt ggagctatca tcagatttcc taataagaaa gagagaagga taatgagaat
     7981 taacaaatac atcgcccatg caggccttgc tagccgtcgt aaggctgaag agctgatcaa
     8041 gcgagggctg gtgaccctaa atggtcaggt gataacagat ttagcaacta ctgttaaatc
     8101 aggcgacctt gttgaggtag aggggattcc tatttacaat gaagagaagg tttattatct
     8161 cctcaacaag cctcgtggtg tcatctcaag cgtttcagat gataaggggc gtcagacagt
     8221 gattgatttg ctgccgcagg ttaaggagcg catttaccct gttggtcgct tggactggga
     8281 tacctctggc ttattaattt tgaccaatga tggtgatttt acagataaaa tgattcaccc
     8341 ccgtaatgaa atcgacaagg tttatctggc tcgtgtcaag ggagtggtaa ctaaagaaag
     8401 cctgcgtccc ttaacacgtg gtgtcgttat tgatggtaaa aaaacaaagc cggctcgtta
     8461 ccgcattatt cgtgttgagc ctgataaaaa tcgctctatt gttgaactaa ccattcatga
     8521 gggccgtcat catcaggtca agaaaatgtt tgaagtggtt ggacacttgg ttgataagct
     8581 atcaaggaca cagtttggca gccttgatgt cagaggccta aagcccggag aagccagaag
     8641 gctgagcaaa aaagaagtca gccagctaca tcatttagcg agcacacgaa aatgatcaaa
     8701 gccctactca ttgctcctgt cagagcctat cagaaatata tttctccctt atttcctcct
     8761 tcctgtcgtt atcagccgac ctgctcggcc tatatgatta cagctattga aaagcatggt
     8821 gctaagggtg ttttgatggg acttaccaga ctattaaggt gccacccttt tgccgctggc
     8881 ggagaagacc cggttccaga taccttttcc ttaaaaagac atttcataac gcatgaaaaa
     8941 atacaggatt ttgaccaaaa aactgattga caatagcagt taaagtgcta taatagcagt
     9001 taagtattcg ttggtttaaa tcaaacctgt tatgatttaa gttagcgagt caccgtcaac
     9061 cacattgttt gctgagcatg actccgggca gtgtggtttt tttgatgaaa agagtaagcg
     9121 ggacaagcat gaaacaagaa atcattaata gacaatatag ggaaaaagat agtcaaaacc
     9181 atgtggtgct ctttcagcca caaattccac aaaacacagg aaatattgct aggacctgtg
     9241 ctgccaccaa cacgccttta catatcatca ggcctatggg ctttccgatt gatgaccgta
     9301 agatgaaaag agcggggcta gattattggg ataagctaga cattagattt tatgatcatc
     9361 tagatgaatt tttagcacaa tgtgatggga gcttgcatgt gattagcaaa tttgctgata
     9421 gggtatactc agatgaagcc tacaatgatc gtcagtctca ttattttttg tttgggcgtg
     9481 aggatactgg tctgcctgag ccctttatgc gtcaatatgc tgatagggca ctcaggattc
     9541 ctatgaatga tgagcatgtc agaagtctca atgtctctaa tgctgtttgc atgatcgtct
     9601 atgaggcact tagacagcaa gcctttaagg gcttagagct tagccatacc tatgagcatg
     9661 acaaactaaa atcataataa gcatatcgca aaacatcagt tagattgaag aagtatccgt
     9721 aggggagctt cttcagtctt tttttattgt attctttgct tattaaccaa gcagttgaca
     9781 cgaaaattcc aatagatcgt ttaaagccaa taaaaccatt attaggcttg cattacaggc
     9841 aggtatcaaa gaaagatata gaaaaatata ccagaaaaaa atctcataaa agtgtcaaaa
     9901 tagtaaaaaa tcgccaaaaa tatgtcaata ttataccatt attatagtat aatatttata
     9961 atcatattat aatattaaaa tatctggtgt ctagctgttt ttgtaaaagc aaaaaacctg
    10021 caccacctta tgataaagca taaaggaata taagcatggt agtctaccta aagcaacaca
    10081 aaaattactg gaaattagtc agcatagcag ctttaatcat tattttagga ggaatactaa
    10141 caatgaattg gcttaatggg gatagggaca ataaaggcga gaataactac tatcaagtag
    10201 agaaggattt agcaatggaa attgttagtg agtttgaagg agtaaaagag attagctttc
    10261 ttagtccagt acaatccaaa gaaacagggt attggggaac aacagctact ataaataaaa
    10321 ctaatgagat atcttattct ttttcgatga ctttttcagg aaagcttgat gattattctt
    10381 actattacga taaatgtttt aaattagtga agcgtcacaa aaaattgaca ttaagtcaag
    10441 tggatctaac agatattgat attaaatatt ctaagggagg gaaataaatg ataactgaca
    10501 aaaactataa ctggctagct ggaaaagtat atgatgttga tgctaataaa gtaactattc
    10561 ctgttagaaa aaatacggat attcttaatc gttatgtcaa agtccttgaa gccgaagaca
    10621 atcctgacaa cggtatgcag tttacggtgt caaagagtaa taggaatgtt ctagctttaa
    10681 attataaact aaggagcttc tatgacagta aaaaagaaag tcatcatttt attaggaatg
    10741 gtagcaattt tagtaatggg aggtatattt atgtttagct ataatcagaa tcaagcgaaa
    10801 atgttagaac gacaatttaa ccatgaacaa aaacgaattg tcttgtattt gttaaatcat
    10861 tatagcggaa ttaatgagat agaatttaat gatattgaa
//
LOCUS       DARYLD010000067        10898 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYLD010000067 DARYLD010000000
VERSION     DARYLD010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10898
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            93..449
                     /locus_tag="TU651_001678"
     CDS             93..449
                     /locus_tag="TU651_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897650.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            973..2022
                     /locus_tag="TU651_001679"
     CDS             973..2022
                     /locus_tag="TU651_001679"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL0897651.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
     gene            2353..2595
                     /locus_tag="TU651_001680"
     CDS             2353..2595
                     /locus_tag="TU651_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897652.1"
                     /translation="MISCTLLASLLLTGCHSLSLQLAEAVQEKPIQAVTVEDLTRHGI
                     AESLKAYLQTMGLTNEEAMKQYEEVLSDEIIQYFSS"
     gene            complement(2717..3931)
                     /gene="thiI"
                     /locus_tag="TU651_001681"
     CDS             complement(2717..3931)
                     /gene="thiI"
                     /locus_tag="TU651_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL0897653.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(3933..5075)
                     /locus_tag="TU651_001682"
     CDS             complement(3933..5075)
                     /locus_tag="TU651_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL0897654.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKPAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            5315..5755
                     /locus_tag="TU651_001683"
     CDS             5315..5755
                     /locus_tag="TU651_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897655.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(5825..7177)
                     /gene="gorA"
                     /locus_tag="TU651_001684"
     CDS             complement(5825..7177)
                     /gene="gorA"
                     /locus_tag="TU651_001684"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL0897656.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(7371..7712)
                     /locus_tag="TU651_001685"
     CDS             complement(7371..7712)
                     /locus_tag="TU651_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL0897657.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(7773..8939)
                     /gene="aroC"
                     /locus_tag="TU651_001686"
     CDS             complement(7773..8939)
                     /gene="aroC"
                     /locus_tag="TU651_001686"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL0897658.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(9052..9732)
                     /locus_tag="TU651_001687"
     CDS             complement(9052..9732)
                     /locus_tag="TU651_001687"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL0897659.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(9729..10892)
                     /locus_tag="TU651_001688"
     CDS             complement(9729..10892)
                     /locus_tag="TU651_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL0897660.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         3280 a         2502 c         2013 g         3103 t
ORIGIN      
        1 aaacatttga cttttgacag attttgagtt aaactaacat tgtgataagg aaaatatcac
       61 aaaaataacg acggacaaag gaaccgttgg aaatggagga cacttatatg acacaagctt
      121 gtaagaaatt tatggtttct acaatggctg ccctagcttt ggcaggagtc tgcctaacag
      181 cttcaaccca catcagcaaa gctgatgact atgtttatgg tgacgtggaa tatcttttga
      241 cgcctaagca agaaggatac gatgatttgg tgtcattctt ggagagtcta ggccttaacc
      301 attttgatgc cactctttat tcggactcta tggctgatca agattacaaa aagctactag
      361 ctgactttaa gggtaaaact cgtagtgaag ttatttctgc agttctatct gaattagcta
      421 aattttataa cgactattcc cctttttaat gaaataaccc aataagttat catagatcaa
      481 aactgctcag acaaccttcc gagcggtttt aacttgatag agctatgctt ctctttgtca
      541 atctgcttag taaccagacc atctcctaaa tcgtccgcct agctaatcaa gtaataactg
      601 caccattgtc cttactatcc tagctaatgc cctgatttgc tgactaagct tggctaagat
      661 tgtgcaagaa tcccaataac atcaaagcct acactagctc ttattagtgg tctcaataat
      721 aacagctcat gtctaaggca tgacaccaac aataccaaac ggtatcatca ttggtaaaat
      781 aggtaacgct aacataaacc aagctgaaat atccattata gagatccagt ctgccagcat
      841 ctctactatc tcatcactat ttactaataa ataaagctta tcaaaagcat tgtctcaaca
      901 aaatattgtg ataatatata aatgtcatta acattattta atgataatat caccataaca
      961 agaaagggtt atatgaaaac aatagcttat ccaaataaac ctcactcctt atcagctggt
     1021 ctcttaactg ctatagctat ttttagcctg gcgagttcaa acattactta tgctgacgat
     1081 taccaaagga atgctacgga agcttatgcc aaagaagtac cacatcagat cacttctgta
     1141 tggaccaaag gtgttacacc actaacaccc gagcagtttc gatataataa cgaagatgtg
     1201 atccatgcgc catatcttgc tcatcaaggc tggtacgata tcaccaaggc cttcgatggg
     1261 aaggataatc tcttgtgtgg cgcagcaacg gcaggtaata tgctgcattg gtggtttgat
     1321 caaaataaaa cagagattga agcctattta agtaaacacc ctgaaaagca aaaaatcatt
     1381 tttaacaacc aagagctatt tgatttgaaa gctgctatcg ataccaagga cagtcaaacc
     1441 aatagtcagc tttttaatta ttttagagat aaagcctttc caaatctatc agcacgtcaa
     1501 ctcggggtta tgcctgatct tgttctagac atgtttatca atggttacta cttaaatgtg
     1561 tttaaaacac agtctactga tgtcaatcga ccttatcagg acaaggacaa acgaggtggt
     1621 attttcgatg ctgttttcac cagaggagat cagacaacgc tcttgacagc tcgtcatgat
     1681 ttaaaaaata aaggactaaa tgacatcagc accattatca agcaagaact gactgaagga
     1741 agagcccttg ctttatcaca tacctacgcc aatgttagca ttagccatgt gattaacttg
     1801 tggggagctg attttaatgc tgaaggaaac cttgaggcca tctatgtcac agactcagat
     1861 gctaatgcgt ctattggtat gaaaaaatat tttgtcggca ttaatgctca tagacatgtc
     1921 gccatttctg ccaagaaaat agaaggagaa aacattggcg ctcaagtatt aggcttattt
     1981 acgctttcca gtggcaagga catatggcag aaactgagct aaccagtcat cattaggaac
     2041 agaccaagtg cttattggtc tgttttttcg tctaacaata gccctattag ctcactgtca
     2101 ttggttaaag cttgtcatga actctttaag ctcttgtttt gttaaacatt aatgtgcctg
     2161 ttgttctttt ctaagataag taaactagat acctgacata aaaaacaaac gttattattt
     2221 atcttaataa aaaaatcatt ttttgaacat aaaatacgaa tattatacta aaaataaatc
     2281 caaatagttt acaatttatg gttgttttca tataattttc atgaaaggag ggaaatatat
     2341 gaaaaatcta tattgataag ttgtacacta ttagccagtc tcttattaac tggctgtcac
     2401 tcattgtctt tgcagctagc tgaggctgtt caggaaaagc ctattcaagc ggttacggta
     2461 gaggatttga ccagacatgg cattgccgaa tccttgaaag cctacctaca gacgatgggc
     2521 ttaaccaatg aagaggctat gaaacaatac gaggaggtcc tttctgatga gattatccag
     2581 tattttagca gctaaataag agaatttgag caaaatcagc taaaaacaaa agccagagcc
     2641 tttaataact aataggtctg gctttttttg actgtttaga tagactgctt atgttgtagg
     2701 gctaggtgcg cacctcctac aacaattcct caataagcgt tgataagctg tcagtttcga
     2761 tttcaggagt gatctcagtt actctgatcc ctgccactgc tcgctcgacc aatccgtcga
     2821 catcaaagcg agactcatat cgttcaacat ttgctagctt gggattggtt ttgggacgat
     2881 caggagcaaa aatagtacag cagtcttcaa agggctgaat ggaaatatca aaggtgtcaa
     2941 tttgctgagc gatatcaatg atttctagct tatccattgc cacaactggt ctgataatcg
     3001 gagttgaagt gactgcatta atagcctgca tgctctctaa ggtctggctt gcaacctgtc
     3061 ctaagctttc accgttaata atcactaaag cctttcgctt ctcacgaata gcatctgtga
     3121 tccgcagcat gaagcgtcta gtaagtgtca tcaaataggc ttcgggtgcc ttatgcttga
     3181 tctcctcttg aatctcggta aatggaacct cgataaactg tatattacct ccaaaacgtg
     3241 ttaagcgctg cgttagatcc ttggcttttc ttagcgcacc aggactggta tagggtgggc
     3301 ttgcaaaatg cactgcctca atctcaacac ctcgtttcag ggatagatag cccgcaaccg
     3361 gtgaatcaat accacctgat agcatcagca ttccctttcc tgaagctcca accggcagcc
     3421 ctccagctcc ctttatatct tcgtgagaca gataagcagc ctcatcacga atttcgacct
     3481 ttagggtaac atcaggattt ttcatctgtg ccttgatatg cggcaaagcc tcaaagacgg
     3541 ctgctcctaa ggtgtggttg aggtcgcggc tatctagctc aaactgatgg tcactacgct
     3601 tgctggatat tttaaaggtt agcccttcgc gatacaagga gctcataatc tcctgaactg
     3661 ctgctatcag tacagggaca cttttttcaa ctttatagac aggagataag ccctgaatac
     3721 caaacaccgg ctttaaggct tcaatcacag acctatcatc tgcaccatta agtaaaacat
     3781 gggtcctgtc tcgagttgat ctgactgtca cctcagaata ggcagaaaga acatcttgaa
     3841 tattagcttt tagccgatta ataaaccgca tacggttttt tcccttggtc gataactccc
     3901 catgacgaac cattatttct gaatatttca tattatctaa ccttttgtgt tttttcataa
     3961 atctgtttaa aaatcgttaa aaattgctca acctgtccca tatcattatc atcatctagg
     4021 ctgatacgga ctgctgtttg agccaatgct gctggaattc ccattgagac taaggttcct
     4081 gccggctttc caacctttga tgagcaggca ctcgttgttg atatataaat ctcatgcttt
     4141 tcaaatgcgt gcacaataac ctctccacga acgcccttta taccaaaggt cagaatatga
     4201 ggagcaaaat catctatctc agaaaagaga atggtatcct cataggcctg caaggcttga
     4261 taaataacct ttttcatggc tgctatcctt gcttgagatc tatcctgtct ttctgtgatg
     4321 atccttaaag ccttggccat acttgcaata gctgccacgt tttcagttgt cgaacgtagc
     4381 tcatcttctt gaccgccacc gaccaataag ggagtgattc gctttcctga ttttttataa
     4441 agaaagccaa caccacgaac agcatgaaat ttatgaccag aaaaagaagc taagtcaaca
     4501 cgcgcggtta agtaagcctc aacaggaagc ttcccaatag cctgaacagc atcgacatga
     4561 aaggtaatgg tgggcttatc agccaaaagc tctgatatgg ctgcaatcgg ctgaattgac
     4621 ccaatctcat tgttaaccgc cataatggaa actaatatgg tatcttttcg gattaaggca
     4681 gctagctttt tgacatcaac aactccctta tctgtgacag gagcataaga cagctcaaag
     4741 ccttgacttt ctagccattt ggcgctttct ctgacagctg ggtgctcaat ggctgagaca
     4801 atgatgtgct taccaaagtg agatttttca aaggcaatcc ccttgatagc ccaattgtcg
     4861 ctttccgttc cgccagaggt aaagaaaatc tctttggcct ctacatcaag taaggccgct
     4921 atttgcctgc gcgaagcctc caatatacga ctggcattgg ctcctagctg atggagacta
     4981 gagggattgc cgtaaatctt actggccact tcctgatacg ttttaagtgc ctcttcgtaa
     5041 ggcttggtag tggctgcatt atcaaaataa atcatgtgtc accttcattt ttattcaata
     5101 ctttattgta tcacaaattt gatgaaatga aaaaatagat ctttttgcag gataggacaa
     5161 ctctatccta gacaataagg taaaccgttg acttgatttt tgttctagat tatactggta
     5221 gatgatagag ctaagtctga aatgcctgtt agccattaaa gacctaaagc atttgacttt
     5281 agctagccta tgactcgtta aaggagatat tctcatgtca tcacattatt cacgtcaaca
     5341 aaagcctaaa aaatcagcaa gtattcccac aaagcatatt aaaactggct ttaccgccct
     5401 tcaaaaaacc attgccttag ttggtagtgt tctgagtatt gttgtagcga caatcactat
     5461 taatcgagct ctacaaccat caaatgagca acccaaaagc gattcctctc cgtcatcaac
     5521 atcaacgatt gtgaaaatta ttgaaaagga gtcgtcacac tcaaataagg aagagactga
     5581 caagacagaa actaattctg attctagcgg tactcaggcg acacatacta ctcctagctc
     5641 agctgatcct gctactaagg atacagaaaa acaacagaat accgaaacgg aagcaccggc
     5701 tgctaatcaa cccacagcta atgagccagc tcctaacagt acaagcaatc cataacacaa
     5761 aacacgataa caggcaattc agataagctc tgaattgtct gctatcgtgt tttatcatgt
     5821 gctgttatct catggtaaca aactcttcag cacctgtagg gtgaatggca acagtattgt
     5881 caaaatcagc cttagtagcc cccattttaa tggcaacagc aaagccttga atcatctcat
     5941 caacaccata accaatacca tgcagaccaa cgatggtctc ttcttctcct gcaacgatca
     6001 atttcattag gcagggctgg cgatgactag taatagctgt atacatggac gtaaattgtg
     6061 attgatagac acgaacagcc gcttgcccat aggcttgaat agctgcctct tctgttaagc
     6121 cgatcgagcc aattggcgga tggctaaaga caactgtcgc aaccttgtta taatcaagct
     6181 tttcattggg cttattatga aacaagcgct ctgccaagcg acgacctgct gcgacagcga
     6241 ctggggtcaa agcaagcttt ccattaacat caccaacagc atagatgcca tcaacagatg
     6301 tgttttcata agcgtcaaca gcaatatagc ccttcttatc cagctcaact cctgtatgct
     6361 ccaagccaaa gcctgtcaca tttggcttgc ggccaattgc ccaaatcact tggtccactt
     6421 caagcctacg accatcggac aaatgcactt gaagagagcc atcattagcc ttggtaacct
     6481 tagtaacatc ggcattggta tgcagccttg gtccagatac cttcatctca tcgaccagaa
     6541 cctggataat atcctgatca aaggtcctca gtggcctgtc atagcgaacc agcaaatccg
     6601 tctgagaacc tagggcattg agcactcctg caatctcaac agcaatatag ccagcaccga
     6661 caactgctgt tcgttttgga atatcatcta aagcaaagaa accatctgag ctaatcccca
     6721 gctcagctcc ttcaatgtca ggaaaaatag gctgaccacc agtagcgatt aaaatatggg
     6781 gggctgtata ggtcttacct gcaatgtcaa ccgtatgctg atcaataaat cgtgcataat
     6841 cataaatacg atcaaccccg ttatgctcaa agcccttctc ataagaggca tgaatacgat
     6901 caatataggc ctgacgattg ctttttaagg ttttaaaatc aaacctatcc tctaacaccg
     6961 taaacccgta atccttcgca taggtatgaa tcgtttctgc tacctgtgcg ccataccaca
     7021 tgaccttttt aggcacgcag cccaaattaa cacaggtccc tccaatagcc ttgccctcag
     7081 ctaataggac cttagcaccg tacattgctg cacgattcgc cgaggcaatc ccagcgctcc
     7141 caccaccaat cacaatataa tcatactgaa ttgccattaa tttaccacct ttactcttaa
     7201 tgcttgcctc aatagatttg ttattaagct atcattattg ctttatttta atctactgtc
     7261 atttgactat aacataaaat aacttgtgtc tcaaatccct gctacgacaa aaaaagattg
     7321 tgataagcat caacaatcct ttcttctctt aatcctaagc cagcttagct ctacttggcc
     7381 aaatccttca atggtgcaaa tacaatccgt tcaatatcat taacatagac ggaaagagcc
     7441 tgctgagcgt taaaataccc ttttaatagg tcattggcct caattttttg gctgagagcc
     7501 tgaatatctg cctgctctgt ctctgttggc agctgaccgg tctgcatgag tccttgcaat
     7561 ttttcttgca cagcaacaaa ctcatcaaat agctgactgg cagcctcatc tgccttaatc
     7621 tcttctctgg cttccaaggc cttgcgatac tctgggagcg cacgaacagc tcgctcaagc
     7681 ttattggcat aatcataaat atcttgggac atctggatct ccttttatca tttattatcc
     7741 ttatcatatc acaatatcaa gccatttgtc gcttaaaaat gatgaacata gtcacgatag
     7801 gcaaaaaaag cctgctttaa atcggtcata ttgtctgatg gaaattgttc caaaatctct
     7861 tttgtgatga cagttgctac aacattttcc atcacgacac cggcagccgg cagagccgta
     7921 ggatcagaac gctcaacagt agccttgtaa ggctcgtgcg tctcagtatc cacagacatt
     7981 aggggcttgt agagggtggg aatcggcttc atcacccctt tgacaacaat aggctgacca
     8041 gtagtcatac ctgcctcaaa gccacctagt cggtttgttc gacgactgta gccgcttgtc
     8101 tcatgccaaa tgatgtcgtc catgacctgc gagccttttt ggtagcccat gtcaaagccc
     8161 ataccaaatt cgaccccttt aaaggcgttg atagacagga cagcctgcgc gattttggcg
     8221 tctaatttac gatcccactg aacatatgaa cctaagcctg ctggtaagcc atgaatgagt
     8281 gtttcaataa taccaccaag cgtatctcct tcttttttga cttgatcaat atgggccttg
     8341 atagtcgcct cttgcttggg attgacaata gataaatcag aagactctgc tacttttttg
     8401 atatctgcaa aggacatcgc ctcaggcaca gctacctcga taccaccaaa aactaggaca
     8461 tgattagcag tttcgatccc aagctcagta aggattgcct tagcaattgc accaacggcc
     8521 acacgcatcg ctgtttctct ggcagaggag cgctcaagcg catttcttaa atcatcaaaa
     8581 cgatatttga tccccccaac caagtcagca tgaccagggc gtggacgagt gattttacgc
     8641 ttgaacttga tttgctcttc aacagcctca acagccataa tgtctagcca tttttgatgg
     8701 tccttgtttt gaatggttaa agtaattggt gctcctgttg ttttgccatg acgaacacct
     8761 gaagagatat gcacacgatc tgattcaatg cgcatgcgtg cgccacgacc atatcccccc
     8821 tgccgacgct tcagttcctt gttaataagc tcagctgata atgctaagcc tgcaggaatt
     8881 ccctctataa tggccgtcaa agcttgtcca tgtgactcac ctgctgttaa atacctcatt
     8941 attcctccat ttatcaatca tagacataaa aagcaaacct gccctcctct agacaactaa
     9001 aagacattat tctaagctat ccaagagaat aatgtctgtt accgtatctt atcaatcctc
     9061 agattccaaa acatgaagaa tccttttcat atcagccaag gaaacctgcc ctggtgcact
     9121 ggcttgatct aaggacacaa aagtccacga ggaccctaca acatcacctg ccaagcgtga
     9181 tagtctgcct agctttccca ttgacatggt tgcaaattcc tgctctgggt taagtgtttt
     9241 aaagcctctg gtataattca tcaaatccaa aacgtcctgc tcgctctgtg gcatgacagc
     9301 aatcttgaca acgcgaggag ctagcttagt catctccgaa aaagcctcca tcagattttc
     9361 aggcgtctca tcaaaattgt gataagacaa gacaagattc ggaaagtcaa gcatttcatg
     9421 aaagacagcc ttgtgactaa agtattcaaa gtcaatatag tcaggattat aaatcgcatt
     9481 gatctccttg atcaaatcaa cgtattcctg atcagaaagt gtaatatgcc ctccttcttg
     9541 acttgtacga agggtaaaaa taatctctct acctgcaaat ttttcaaaaa tagctggcgc
     9601 tacagaaaca atatcctcct taggaagaaa gtctgctcgc cactcgatta aattaacatc
     9661 ttgatattta gaaacgtcga tagattgagc ctcttcaaca tttcttggca tgactggtgc
     9721 tacaattttc attctcgtac ccttatagta aataccttta aataattact tctttcatct
     9781 gctttattga tagtaaaatc acttggaagc tgctcaagtg tcatctgagc taatggcctg
     9841 cctcccaatc ctttgataat ttgcttttta aactggttaa cagtcatatt ggcagcattt
     9901 gttgaagcga taattgttcc cttgggggcc aataggtcta gagcctcagc gattaattga
     9961 tggtaatcct tactcactga aaacgtctgc tttttgtttc tggcaaagct tggtggatca
    10021 ataataataa gatcaaaaga aagttgcttt cgcttagcat acttaaaata gtcaaaaacg
    10081 tccataacca caagctgatg actggatagg tccaactgat tttgaacaaa atgagccttt
    10141 gataactctc tggagcgctt tgccaaatca acagaggttg tctcaactgc accgcccatt
    10201 gctgcagcta cagaaaaagc tgctgtatat gagaacaggt ttaaaacagt ctttccaagc
    10261 gccaagccgt ccaccagacc tcgtctaacc tcatgctgat caagaaaaat ccctgtcatc
    10321 aagccatcat ttaaaaatac ctgataggct acgccatttt ctaaaatggt aaaggtatca
    10381 ggagcaaacg cgccatacaa atgagccgtc tccttatctg gtcccttaaa gcgaatcttt
    10441 tcataagctc ccctgacctc aggaaaaacc tctcgaaaag cctgaataat aagctccttt
    10501 tcttgataaa caaagacatt ataccaagaa aataaagcaa agtccttata gaggtctatg
    10561 gttagtcctc caaaatcatc accgtcttgg ttaaaaagac ggtaagcatt tgtccattca
    10621 gacgcggcaa aatgctctct tttcttctta gctgtcttaa ataaggtcac aaaataagaa
    10681 accgacaatt tcttaacaga ccttcctaga taccagccta ctcccttatg ttgctttgaa
    10741 aggtaagctg tgccgatgag ctgatgagat gaattcacaa gctgcactaa ctggtagtcc
    10801 caaatggtgc catcaaaatc cttttcatct agtaattgta tccctgctgc tatcttgcgt
    10861 tcaacaaggg gattaataca gaccttattc atagtttc
//
LOCUS       DARYLD010000068        10764 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYLD010000068 DARYLD010000000
VERSION     DARYLD010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10764
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..362
                     /locus_tag="TU651_001689"
     CDS             <1..362
                     /locus_tag="TU651_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897661.1"
                     /translation="FNTSKNIKITREIKEYIQEGNIIAAEQLLSEKLDPTLFSLGSVE
                     KDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTKKLERAKELYARALHDLPD
                     CKLEFNQFVEYYLIGRN"
     gene            798..1217
                     /locus_tag="TU651_001690"
     CDS             798..1217
                     /locus_tag="TU651_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0897662.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            1218..1541
                     /locus_tag="TU651_001691"
     CDS             1218..1541
                     /locus_tag="TU651_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897663.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            1800..2429
                     /locus_tag="TU651_001692"
     CDS             1800..2429
                     /locus_tag="TU651_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897664.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            2411..2833
                     /locus_tag="TU651_001693"
     CDS             2411..2833
                     /locus_tag="TU651_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897665.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            3092..3496
                     /locus_tag="TU651_001694"
     CDS             3092..3496
                     /locus_tag="TU651_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897666.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            3493..3921
                     /locus_tag="TU651_001695"
     CDS             3493..3921
                     /locus_tag="TU651_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897667.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            3914..4327
                     /locus_tag="TU651_001696"
     CDS             3914..4327
                     /locus_tag="TU651_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897668.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            4590..4982
                     /locus_tag="TU651_001697"
     CDS             4590..4982
                     /locus_tag="TU651_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL0897669.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            4983..5306
                     /locus_tag="TU651_001698"
     CDS             4983..5306
                     /locus_tag="TU651_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897670.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            5619..6089
                     /locus_tag="TU651_001699"
     CDS             5619..6089
                     /locus_tag="TU651_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0897671.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            6073..7166
                     /locus_tag="TU651_001700"
                     /pseudo
     CDS             6073..7166
                     /locus_tag="TU651_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(7460..10606)
                     /locus_tag="TU651_001701"
     CDS             complement(7460..10606)
                     /locus_tag="TU651_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897672.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVKTNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         3385 a         1832 c         2335 g         3212 t
ORIGIN      
        1 tctttaatac tagtaaaaat atcaagatta caagagaaat caaagagtat atacaggaag
       61 gaaatattat agcagctgag cagttgctct cagaaaaatt ggatcctact cttttttcat
      121 tagggtctgt ggaaaaagat aaattaaccc ttgtaaaaga aaataatgcc tatagtttaa
      181 tatttaatga tgtgcaaatt ctaactgatt taagttcatt acgtgcttac attgttttat
      241 ttaattacac taaaaaactt gagagagcaa aagaattata tgctagagca ctacatgact
      301 tgcctgattg taagttagaa tttaatcagt ttgtagaata ttatttgata ggaaggaatt
      361 aataaaagaa ctattgaaat accatatggc attttgagtt cagatgccca gtcatggcag
      421 gaggcagcga acaagatgct cagcgagcta cattagtagg caatatccta ggaggattcg
      481 ccgcctcaag cgtcgccaga cggttcagct tgaatgagcc aatagcagct agggtgacga
      541 aaccgaccta cagccgccgg cagcttttga agaaccttga gaacagcagg ctggcaagag
      601 aaagctcgag gtttgatgat tatcttcgaa gagaataccg gttaaaggga aggtattttg
      661 cagaaagaac cactatttca aatggaaaga taggttatct ttcatctgac tattttgaag
      721 gcaagcaaat tccggttcgc tctagagctt ttgttgacga agcaggccat attaaatggc
      781 caaatgccga tggctttatg gtggataatt taggtaatcc tataacggag caggtcactc
      841 tcaaagcagg tcaaatcatt gatcgatatg gatcaagtag tggtcgattt accagtccga
      901 tagaaaatgg ggtgacatta ccatttaata aacgtggatt accctaccca gaaggatatc
      961 aagactatta taagtacgaa ttagtaatgg atttgacgaa gaaaaatatt gttaatgcgt
     1021 attatcaatc tgaagagatt ataagaaaac aaatatctgt agaaatgaaa aaatggaatc
     1081 tttcctttga tgatttagct aatattcaga agggtgagat taccaaagta tttgggcaag
     1141 gtggaggaat tcagattaaa tttccgacag gtgttggtat ttacaagaaa atgggtttat
     1201 taaaggagat taactagatg gataatacaa atatattgaa ttggaaaaaa gatattgaag
     1261 aagcaattaa aaatcgaggt tttgagagtt tacattatgt tttatttgat gaagaaaagc
     1321 gacttccttg ggcatttcat ctttatcaaa aaaatggaaa attctatgtt gaaggaagag
     1381 atgagcgatc atatatcatt ggtcatagca gggaatatcg taaatttgat gatgccaagc
     1441 atgaattgct taaaaaatta gaattagtta tagaatctaa tcggttaaaa aagcagttag
     1501 gtgaacctac agaatatccc tcaccactat ggaatgaatg agtttcatgt attgtatgcc
     1561 atggcaccaa gcttttagga ggcagcgagc aagacgccca aagagcaaca ttagttggga
     1621 atatcctagg aggacttgcc gcctcaagcg ccgctagaag gttcagcttg aatgagccaa
     1681 tagcaactag ggtgacgaaa ccgacccaca accgccagca gcttttgaag aaccttgaga
     1741 acagcagact ggcaagagaa agctcaaggt ttaagaatta tgtagcaaga gaaaaattca
     1801 tgacaaccct tgcaggcatg agtcctgagg atagtcagcg ctatattcaa tggcacaaat
     1861 acgcaaaggc tggacttagt ccgtcagatc gagtaaggat tctagaaata tctgagaagg
     1921 caccgaagat agagtatctt ccgggaaaaa catcagatag tatattggca atatccaagg
     1981 gtgatcgtcc aaatgtggag aaagtctaca gtccagatta tattggattt catagaaaac
     2041 aatttgataa cggtgcaact agatttcaga aatttaagcc caatgtagat taccaagacg
     2101 gtttagttgg tgacgattta ggcaatagtt tttggttaag taccaaggac gcggatatta
     2161 tccaggagat aggaaaggga aataaccgtc tttatgagac actcttaggc tttgatgaag
     2221 ggtatttaga agatggtccc ctctatcgct tagatgtttc accagaagtt gtttcacaaa
     2281 aaggtgtttc aataccaagt ggtaatgaaa aaggggcaaa tagctggtgg cgtcctggag
     2341 gtcgtactta tccggggaat ataccagagg gagttatgca aggtatcagt acaaagaaag
     2401 gagatcacac atggcacgca gtcaattaga gtgggaagat gttagtcaat atgaggaggt
     2461 aaagggctat ggtcaaaggg tgtggaagca tcaagggaaa tattactttg ttgccgaaga
     2521 aggtggcatt gctgttcaac gagtagtata tgagttaccg tatgacttat ttgaattgtt
     2581 ggaaagtgga gaacgtagtc ttggagatgt tcattcaaag ctacaagatg gtaattggcc
     2641 accaacagaa gaggaaaaga agcaaagtca tagaaaattt gttattgaca caccaactgc
     2701 gctgattgca gaccctacta gtgtgtctct gttctcagaa gaagaattat caaaattagt
     2761 gccaatcgct gaacaacagt ggatagattg gaagggaaag ctgccagatg attatgtcag
     2821 tcctttgaaa taatgtttaa gatagcggag ccgagattag ctctgctatt ttaaagcatg
     2881 ttcttaataa ttagcctgcg acagcttatc agggagtagc tcgtcacctt gaagccaatg
     2941 ccaagcgtct ccaagcgccg ccagaaggtt cagcttgaat gagccgatag cagctaaagt
     3001 gacgaaatca gcgaaaataa ccctttctga aaaggtacta gacacaaagg ttcggtttga
     3061 tgagtctcgc attgtggctt acgcagaaag tatgagtaag aactatacag aagctgacgt
     3121 ggccaaatta accgagctga ccacccacaa tgcaaaaacc aaaacagctt tgctgggata
     3181 ttacgaagca aacagcgtta cttcgtatga acaaattgca catcaaaata agttaactta
     3241 ctttgatgcc ggaagtgatg gttggaatgc gatgtcgaga gtggattcta agctagctca
     3301 aagggttaat cgtgaatttt tgataaaaca aattgagaaa agaaaaacat ttatattaac
     3361 gtctaatcca tatactgctc aatcaatcgc agatgttagt ggtatcggga agtcttatgc
     3421 taaagaaatt cagattttag cagaaaatgg atataatatt gaaaaatttg aaaggttttg
     3481 gagggcatat aaatgagtga agaacagtat ttaccagtaa aggaaagctt aggatatcgt
     3541 aacttaaaaa tagctttaat gaatgttttt tcaatagatt tggataagtt tacaattatt
     3601 gaaggagaat ttgaaaattt tggttttcat ttaaattata acaataaaga aatcataatc
     3661 tggattacat caactggtaa gaatagacaa tttgaatatg gagaaggagg acaattgatg
     3721 atttcacttc ctaatccaaa gtatcctgat agatcctttc ttgatagggt aaccttagaa
     3781 agtcttttaa cagacaccga aaaaatagaa gcagttgact atgcttttgg aagatacgag
     3841 catcgtctcg aaatagcgtt ggccattcta aaagattatt tagattcaga cgaagcaaag
     3901 gttttattga aaaatgagtg agcaatattt atcaataaaa gaaagcttag gttataagaa
     3961 cgttaaacag gctttatgga ctattttttc agccaacctt gatgaaattt ctatacatga
     4021 aggagaagat gagaatttta actttgtctt tacatataaa aattgtgaaa tgatgatggg
     4081 aatttatgat actggtaaga atattcaatt ccaagctgga gaaggtggtt tattcagtgt
     4141 aagtttacct aatcctaaat atccggagca gtcatttcaa aaaattgtat cactttctta
     4201 tttaatttct gataaaaatg taagtgaaaa tataagatgg tgcttaggac tggatctgaa
     4261 atctgttgaa tatgttatgc gtgttttgaa ggattatctg gatcaaaaat gtgaagagga
     4321 acaataattc taatcacttc tggagggcat atagatgagt gaagaacagt atttaccaat
     4381 accttcgaag agaataccag ttaaagggaa ggtattttgc agaaagaatc accatgccag
     4441 atggaaaata tgcttatctg tccaatgaca ttgataaagc taccggaaca ccaattcctg
     4501 tccgatatag aaattacctt aaggctgatg gttctattaa ttggccaaac tataatggct
     4561 ttagtcttga tgtaaaggga aggcctatca tgactccagc tttcctaaaa acaggtgatt
     4621 tacttgatag atatggagaa tctggaggaa cattcacaag tccaatcgtt gaccgtaagg
     4681 ttataccatt taacaagcga ggcttaccat acccagagga ctatcaaaat tatcatcaat
     4741 ataaggttct taaggatatt aatatggaaa atgttgaaaa gggttaccat aatttatctg
     4801 atagtagaaa aaaagagtta aatctattaa tgaatagatt tgatttttca ctggtagaca
     4861 tagcaactcc acaaaaagga atgattgatc ttgtctttgg ctctggtgga ggtatccaaa
     4921 taaagttagg aacttctgta agttggtatg aaaaattggg tttaattaag gagataaagt
     4981 agatgaaaaa tttagatcat caaaaggcag aactattaga agcagtccat caattaggtt
     5041 atgatagtct aaggtattcc attttttcta aagagagacc aggagaatgg gaaactgtca
     5101 ttgaatatga taatagtcaa ggcttatatg ttgtgtatgc aactatggat agagctagtt
     5161 ataataagaa attaacattt gaaacatttc aagaggctaa agaaaaattt cttgaaaaac
     5221 ttcggttaga tatccaaatc aacaggtact atgtggaaga gggcatgcct gtaaattacg
     5281 attctccttt gtggtcaaaa aattaataca agtaaaggag aatatacatg gcatgtagtc
     5341 aattagagtg ggaagataaa tgaaataatg gtcctaggaa atgtcccgac tggaaactat
     5401 cttatgaact cttttatgga aaagtgttgc acttaatttg aattttgtca tataaaaaag
     5461 ccctataatc tccatggtgg acttacccac tacagaaatg atagagctaa aaatctccat
     5521 ttggggattt ttttgtaacc aaatgaagca gtcgttcgtt atataggtga agaagggagg
     5581 ggagaattat caggctagat gcttatgaaa gagagctagt ggcttattct aaggaaatta
     5641 ttgcctacct agtgagatca ggtgttgcta aggagctagc gcgtgatatt agtcaagacg
     5701 ttttgttaaa aatgcttgag agtgaccttg ctctgcctcc tgaaaaaata cgtgcctgga
     5761 tgtatcgggt tgctgttaga aaatacattg accgatatag gcgggataag gcttacttgg
     5821 atattctcca aagggatttt tttcatcaag aaagggttgt tgaatttgac caccccaatt
     5881 atgagccgct ttatacagca gtcaatgaat tgccagaaaa ataccgctgg gtcttgtcgt
     5941 tttattactt tcaggaccta tcagtcaagg aaatggcgtc tctgctccat tggtcagtta
     6001 gcagcgtcaa ggtcaacttg atgcggggaa gacgatgcct taaagaaaaa ctaaagaaag
     6061 caggttatac ctatgacgat ttcaactgat tttgaagcca ttgctaagcg ccataaaagg
     6121 aggctgaccc ttaaatatgt agtgctgagt gctggcttag ccttagtagc tcttgtactg
     6181 ggctatatgg gattaaatcg attgacaagc atgaacggtc agtatttaat ggcttattac
     6241 aacaatcgta tacaaattgc ttatcccaat attgatgtta atagcttctt ttacaatgcc
     6301 aattcgcagt ttactggtga gcttcattct gagcggacca aggatattgc tgggatttcg
     6361 gtaccgtttg agccctatag agctccttat tccttgcctt tacccagaga gagatggact
     6421 ataccaatga ataccttgtt tcaggtgatg atggacggtc aacctacaca agaggtacac
     6481 attataaaat gcctcgcttc ttcaacacta aggccaagat cacagaaagc aactatgaca
     6541 agccaacgca ggacctagac tttattgctg acatgtcagg acaggcgatt gaggtagcca
     6601 ttacctttga taagccttat ttattatcgg acatagtcaa gctggttcca gaccagctaa
     6661 agctgaattg gatctggatt ggcacagaaa gcagctatga cacctcaggg cttttccctg
     6721 ctaatttata tggctttaag ccaaactgga aggctaatat gacgtacaag gagcaaaagc
     6781 agttagataa aaaaataaac gatatcctaa aaaaggacag cgaggctgat ttgtctaagc
     6841 ttaatgctgc ttacgataag ccagtcagtc caacggtggc tctgcaaaat tcctatgata
     6901 ccttcaggca ctatctacaa gaggcagctg acaatcattg gattaatagt acctatggcg
     6961 gcgctaatgg atctcattta agtgagcagg aggatgtggc cttatttcta aaaaacaatc
     7021 gcaatgtcaa aacagctaag tttgctggca ttattttaac cggcaaggct gagcagtttg
     7081 cctccttaaa aacagctgat tggatttatg cctcaaatat tggtcagtct gttgccattc
     7141 agccctatca tcagctaacc aagtaaataa aaagcttgtg ctgctaatca agcgcatcag
     7201 gcaaaggata aaaagcctaa aagagattag attaagtaaa tcgatgctta aaaaagctcc
     7261 agcttaggtc aaaagacgtc aaaaggctct tggaggtcag tgtttgatca ctgcttctgg
     7321 ggctttttgc tttgctgcaa tcaaaaaagc ttgaagcagc tctctcaatt gagcatgtcc
     7381 ttcaagctga gactcttata ttttatagta tttgtaagta tagttttagc tagccttctt
     7441 ttaagcccaa gggcttagct tactgtttag tatctttttc taaattattg ataataactg
     7501 gataatcctt caatgcagac ttcatgtcat ttagagtgct ttgatatgct gtttggtctg
     7561 aggctaccaa tgctagcttg tcattccatg ctttatagtt taatggctct gcctttagag
     7621 cagcatctaa atgattaagc ttagtctcct tgtcagtagc tgcttcagcc ttatatcgtt
     7681 catattctga ggcattataa gcgtctatat taagagagta gacgttatga atttggacat
     7741 aaggaagtgt tgtgttgtag ttaccacagc ctgtccagcc tgagacatca tagccgagct
     7801 gataggtatg gtcagcattt aagtagatat aagcacagtg acctggttgt ccaataggaa
     7861 aggctggtac accataagcc tgtgctagca cactacttaa tttagacata gcaccgcaga
     7921 caccaccata tttgatgact tccttgatgg ttggatttgg tccgtaaaag ccagagcttt
     7981 ggacgctcac acctgtttct gggttggtca tgacatagct gatcagtgaa tagcccttag
     8041 taatatcatt acggttaatc atagcaggct tattggtttt aacgtattgt cttaaccatt
     8101 tcatgtcctc atcagtaatt ttagcattga cgacatttcg gatttgctca acagttaagc
     8161 tgtaaaaatc ttcaaatagg atattgccct gctcagcctc tgcaaaggtt gcaaatcttt
     8221 caagtggatc aatcttgcgg ctttcattgt accaagcacc tacaggcttg ttaaattcca
     8281 aggcaaccgc aatggccatt ttgagctgaa taccttgatg tgaggtttcg tatttatccc
     8341 aaatcttaaa ccacaattcc aatgcttcta gctcattggt gaggttatag gtgtttttga
     8401 attggtatga tgacatgcca ccctgtgctg cagaatgggc atagcctgca ccaagatata
     8461 attgcattgc ttcattatct ttgagcaacc aatcaataaa ggctttatgc ttgtcgtctt
     8521 gcttcttgaa gtcctcgatt ttttccttgg ttagtctttt ttcaacggct tgtacgagtg
     8581 tattagtagc tttagcctct agtgcaaata cagaagccaa accacccttg gtgattcgaa
     8641 tctctgcctt atttttaggg aggctaagag aaacagcctt gttttcttca tcataggctt
     8701 tgactctagt atggtgctca ctaccagtta ggcggatctt gtagcccacc ttgaagggaa
     8761 tagtctctgt tttggctgtt agagcttggt ttccaataaa gtcttgtgtg tagacaacct
     8821 tgtcttttag gtctaagacc tcaagctttt cgtaagtccc actgaagtaa acatgtggct
     8881 tagccttttt ggttttgaga gttaaggtag aggcattgta gtcaaccttt aaggttgcgt
     8941 attctgcatt gcctaagcca aggaagcgca gcgttctatt actatcatca atacgctcaa
     9001 gctgcccgtt tctcaccaca taagtgtaag ggttggtatt gttttgcttt agagcgtcat
     9061 tgtggttagt gtagaagcgg ttaggctcct gcttagtgat gactaggtaa tagccttcct
     9121 tgagagtaag gctttctgtt ttagctgttt gggaaacatt acccacgtat tccttagcat
     9181 aaacggtttc ttttttctca ttgagaatgg ttagggtagc gtaattgtta gcgatgtaag
     9241 agtgaggctg tcctttttta gtgactaagc ttgcagtgta actgccgtca gcatagaagt
     9301 agagctgagc aaatatacca tttcctagcc cttgtagagt aaattgctgt agcaggctag
     9361 ctgccttatc aagtaaactt aggatttgct ctttttcagg ctctgttgag tcagtcgcct
     9421 ttttcctaag agcatctatt ttttcttgtg tgacaccact tgctagctta cttgtagact
     9481 catctgtaaa tagagtcagt acctcagact caagctctga gcctgtttta gacctcatta
     9541 gctctagtga gtggtcaaga agctttaagg ttgcttgatt tttagagagt gttaatggcg
     9601 cttctaccgc ataatcatcg tagaatttca ctctggtatg gtgctcacta cctgtcaagc
     9661 ggatcttgta gcctacttta aaaggaatag tctctgtttt agcttcgagg acttgagttc
     9721 caataaagtc ctttgtgtag attacttgat tttctgtatc cagcacctca agcttttcat
     9781 aagatccact gaagtaaaca tgtggcttgg tctgcttggt tttgagggtt agggtagagg
     9841 cattgtaatc aacccttaag gttgcatact ctgcattgcc taagccaagg aagcgcagcg
     9901 ttctattact atcatcaata cgctcaagct gcccatctct caccacataa gtataagggt
     9961 tggtattgtt ttgctttaga gcgtcattat ggttagtgta gaagcggtta ggctcctgtt
    10021 tattgatgat gaggtaatag ccttctttta gctcaagctc ttctgtttgt gctacctgag
    10081 aaacattgcc ggcgtattct tttgaataga cggtttcctt cttgttatta agaatggtta
    10141 tcgtagcgta attagtagag aaataagagt gaggctggcc ccttttagtg accaaacttg
    10201 cagtgtagct gccatcagca tagaagtaaa gttgagcaaa gacaccattg cctaaccctt
    10261 gtagggtaaa ctgctgtaat aggctagctg ccttatctag tagacctagg atttgctctt
    10321 tttcaggctc tgttgagtca gtcgcctttt gctttaaggt atctattttt tcttgtgtga
    10381 caccacttgc cagcttactg caggagttat ctgtaaataa ggcttgggta tcagtcatca
    10441 gttgtgatag cttagcctcg gcagaaggag cagctgtatc acctgcatta actgtagcgg
    10501 ctattccatc agaagtatca gtagttgcat aaacaattgc tggagagagc tgatgtaatg
    10561 ttaatattcc aacacatgct agtgctatta ttttctttag tttcatcgtt ataaagtcct
    10621 tttacaataa aataaagtga ttcaaaactc tgggaaaaga atagctagcc ttaaaactat
    10681 actcgcaaat actataaaat agaaagacta tttaccctcc ttagctcttg atgctgtggt
    10741 gatgatattg ttacggtgct aaaa
//
LOCUS       DARYLD010000069        10617 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYLD010000069 DARYLD010000000
VERSION     DARYLD010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10617
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TU651_001702"
     CDS             complement(56..1390)
                     /gene="trmFO"
                     /locus_tag="TU651_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL0897673.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1772..2485)
                     /locus_tag="TU651_001703"
     CDS             complement(1772..2485)
                     /locus_tag="TU651_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL0897674.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2506..3153)
                     /locus_tag="TU651_001704"
     CDS             complement(2506..3153)
                     /locus_tag="TU651_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL0897675.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TU651_001705"
     CDS             complement(3268..5400)
                     /gene="topA"
                     /locus_tag="TU651_001705"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL0897676.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TU651_001706"
     CDS             complement(5501..6346)
                     /gene="dprA"
                     /locus_tag="TU651_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL0897677.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
     gene            complement(6592..7374)
                     /locus_tag="TU651_001707"
     CDS             complement(6592..7374)
                     /locus_tag="TU651_001707"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL0897678.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
     gene            complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TU651_001708"
     CDS             complement(7355..8209)
                     /gene="ylqF"
                     /locus_tag="TU651_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL0897679.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            complement(8802..9434)
                     /locus_tag="TU651_001709"
                     /pseudo
     CDS             complement(8802..9434)
                     /locus_tag="TU651_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9436..10203)
                     /locus_tag="TU651_001710"
     CDS             complement(9436..10203)
                     /locus_tag="TU651_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL0897680.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(10485..10617)
                     /locus_tag="TU651_001711"
                     /pseudo
     CDS             complement(10485..10617)
                     /locus_tag="TU651_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
BASE COUNT         3131 a         2398 c         1946 g         3142 t
ORIGIN      
        1 gtcctctcca gatgttagct tgtcaactac ccactacagt tgacatggag cctgattata
       61 ccgttaaata agctgccaga tcagctaagg cacgtttagc gatagcttca tagcgttcct
      121 ttttatctct gatacgaggt ccgtcaagct ctttaataat accaaaattg acattcattg
      181 gttgaaaatg cttgctgtcc gcgtgtgtaa tataataagg caggctgcca attgctgttg
      241 tatttggaaa aacaagtggc tcttcttcct tgaatagccg agcagcatta atgccagcca
      301 caagtccaga agctgctgac tcgacatagc cctccacacc ggtcatctga cctgcaaaga
      361 aaagcctgtg attagcgcgt gattggaagc cttgtgtcag aagctttggt gaatccatat
      421 aggaattacg gtgcatcaca ccgtaacgca caaactcagc atgctcaagg cctggaatca
      481 tttggaaaac ccgcttttgc tctccccatt ttaaatgtgt ctgaaagccc acgatattat
      541 aaaggctgcc tgcagcatta tcctgacgca gctgcacaac agcatagggc gtcttgaaat
      601 caccgtcacg tggtcccttg taatcatctg gatattccaa gccaaccggc ttcattggac
      661 cataaagcat agtcttaatc ccacgctttg ccataacctc aattggcata cagccttcaa
      721 aatacttttc cttttcaaaa gcatttaaag gagcttcctc tgctgttgtc aaagcctcgt
      781 gaaaggccat aaactcttcc ttggtcattg gacagttcag ataagcagct tctcccttat
      841 catatcgcga ttttaaataa accctatcca tgttaatggt tgacttatcg acaattggag
      901 ctgctgcgtc gtaaaaataa aagccagcac caccatttaa ggcatgtatt ttttcagcaa
      961 ggctgtcact ggtcaagggg ccagttgcaa ttactgtaat agcatcgcta ggaatgtcaa
     1021 taacctcctc acgaatgatt tcaatcagag ggtgattttc aagctcagct gtaacagcct
     1081 tggcatagcc ttcgcgatct acagccattg ctcctccggc agggacacga tgggcttcgc
     1141 cagcacgcat aataatcgaa tccagacgac gcagctcttc ctttaaaagc cctactgcgt
     1201 tggttaagct gtcaccacga aaagagttgg agcaaaccaa ttctgcaaaa tgggtggttt
     1261 tgtgttgcgg tgttgccttg acaccacgca tctcatatag cttaacagga ataccacgct
     1321 tagcaatttg ataagctgcc tctgatccag ctagaccagc accaataaca ttaatataag
     1381 attgagacaa tagaccaata cctctttggg gacttatcca tcactgattg ccccgcaact
     1441 ctttctttca agtaattacc ctgcctatta taacagaaat aagagcaaag caaaagaagg
     1501 agctgaacag cctcagtctt ttatataaag gagataagcc cgtacctgca cgctctccac
     1561 aaagctagct gcttcaagca ttttagcttt cgcccaatac cagctatcca catatcttgt
     1621 tcactgcagt agttactgga aggcttttta aggcttattt ttcaaaatct agccaaaaat
     1681 atttcaccgg acctcatcat cttgctggta gcagctaaac aagccttttc cagtaaaaaa
     1741 aaagcaagcg aaagcctgcc cttgttcttg tttagaaaaa acacatccat gctgcgataa
     1801 agacacttaa gacactaaac agcgatccaa tcaaataata ttcagcaaag gctgggcttt
     1861 cagagatttt attgtagcga gcaatagact tagcggtaag caccagtccg attgaagcaa
     1921 attgtcccaa caccatacaa acgcccataa caatacgctc taaattacca atagccgcac
     1981 ccgcccctac aatggtatcc attggtttat cactagctgg ctggaattta ttgaagcaga
     2041 gcttaaagat aatattgaca ggcttggtga tcaaaaccat aaaaagcact aacaataact
     2101 gccgagcatg taaccaatca gggatctcag cctgattaac acgagcgact aaagccagaa
     2161 taatgaaaag atgcaagagc tggtccaaca caaagaccca cgaccgatca agcttaatga
     2221 tacgagccca ttttggctta aaataatcaa taaccgcatg gctactaaaa ataaggatcg
     2281 ctgttagcca aagcttaggt atacacatca ccactagaaa caatggagca gctaccccta
     2341 ataagtgcag ccccagataa gcaagctgct cctccttctt atcagcaata acctgactct
     2401 gaaggtgata atctgataaa aaatgacaaa tcactagcag cactaaaata ggatgctgat
     2461 aaaggtaatc agataagccc tgcataggtg gctcctttcc tctttttatt cttgtaggta
     2521 ggtcaaagct gcatggcgac ttctaagata aacctttaca ctgctgcttt ttaagcgctt
     2581 tgacaaggca cttgattgga ggtccaatgt atcgccaatg agctgttggt caaattgttc
     2641 ttcatagatc cctaagtcta aaagcgcatg aaacacctct aattgactag cacgccagct
     2701 agcttttatc gcctcaccag ctgctaaaag gctattgagc accagatcct tgtgctcctt
     2761 atcagtccgt atagctacct gggtattgcc ataatcattt ttttgatgaa tgtaatgaat
     2821 agcctctctg gcacgccaat aggctggacc gtcagcacca atactaatat cagggttaat
     2881 atcagtcaaa atagtcccct gtccaatacc aaacctaaca gggtagcctg tcatggcttg
     2941 attaattaaa tcaatgagtt gaaaaacagg cgcatcatta gtcaacaagc cttgaaattc
     3001 atcacccaga gtcacagata agttagagac gatataggaa gaaaaatcat ggttgagctg
     3061 atccagacag gcctttaagg actcttgcac caaagaacgc gactgaattt gcttagaatg
     3121 gaccaaatcc ccaataacag cgatatatag catgattttc cctcctttta tgacttccat
     3181 tataacagac aaaaaccaaa aagtccatta taatggaaaa tcatctatat ttccgttata
     3241 atggacctct gctaaaatag ttcaaaccta ctttacaatc tcttctttat agtcacagac
     3301 ttcattgcta cacacaacct gcttacctcc acgaattttt ttctcaacaa ggtaatcgcc
     3361 tgacttcgga caagaccgtc ctaccggcaa atcccacgag gtaaagtcac actcagggta
     3421 gcggtcgcag ccatagaaaa tacggttacg ctttgttttg cgctcaatga cttggccttg
     3481 ctgacaagct ggacaagaaa ctccaatttc ctttgtgatg gcctttgtat gatggcactc
     3541 aggaaagtta ctacaagcat aaaacttgcc aaatctaccc agcttaacaa ccatcgggtg
     3601 gccgcacagc tcacaatcaa aaccagccgg ctcgtccttg atttgaattt tttcgatctc
     3661 cgtttcagcc ttggttaact ccttaacaaa tggcttgtag aattggtcaa tcacattctg
     3721 ccaggcttct ttgccgatct ctatctgatc aagcttatct tccatatcag ctgtaaattt
     3781 gacatcaaca atatcaggga agaattccac aatcaattga ttaacaattt cgcctaattc
     3841 cgtcggctca aagcgtttag cagccagctt aacataataa cgacgctgaa tcacatcgag
     3901 tgttggagca taggttgatg gccttccaac accgttttct tccagtgttt taatcaggct
     3961 tgcttctgaa taacgagctg gcggttgagt aaagtgctgt tcaggtgtta aggtaacctt
     4021 tttaaccact tctccttctg tcatttcagg aagcatcttg cttttatcag aatcattgta
     4081 aacagccata taaccgtcaa atttcatctg actgccattg gcaacaaaaa ggacactatt
     4141 ttgctctagg ttaaccttaa cagtatcaaa cacagcagct gtcatctgac tagcgacaaa
     4201 gcggttccaa atcaaggtat agagctttag ctgatcctta tctaaaaatt tagcaatagc
     4261 ctctggcgta tggttcacat tagatggtcg aatagcctca tgagcgtctt gagcaccagt
     4321 agcattttta actcgattgc catgcttaga gtactgacta ccgaaacgtt caacaataaa
     4381 gcctgcggca tcattttgag caactgggct gatacgagta gagtccgtac gcatgtaagt
     4441 aattaaccct tgtgttccat taggaccaag actaatcccc tcataaagct gctgagcaac
     4501 catcattgtt ttacgagtcc gaaagttaat cttattggct gcgtcctgct gcaatgagga
     4561 ggttgtataa ggtaaaggag catgacgcct gcgttctttt ttctcaacct tactaaccat
     4621 aaaatcatcg ctacttaatc gagacaaaac aagcttaaca tcatcattgg tattgagctt
     4681 catctttttg ccattgaggc cgtaaaagct tgcttggaat ttttttgtcc cttttttaaa
     4741 gagaccatca attgaccaat attcttcagg aacaaaggcc ttaatctcat gctctctgtc
     4801 aatgattagc tttagagcaa ccgattgcac gcgccctgct gaaagcccct ttttaacctt
     4861 tttccagaga attggcgaaa tggaataacc aacaatacga tccagtacac gacgtgcctg
     4921 ctgtgagtca accaaatcca tatcaatttt tcttgggcct tcaaaagctt ctttgacggc
     4981 atcctttgtg atttcattga aaacgacacg attgttatca tcaggatcaa gtcccaaaat
     5041 atgtgataaa tgccatgaaa tggcctctcc ctcacgatcc gggtcacttg ctagataaac
     5101 ctttttagca ttctttgctt ctttttttaa ggcattaatc agcggaccct taccacgaat
     5161 attaatatac tgtggctcat aatgattgtc aaaatcaata gacattgatg attttttcaa
     5221 atcacgaata tgaccaaccg aggcaacgac cttatactga cgtcccaaat atttttcgat
     5281 ggttttagcc ttagcaggtg attcaacaat gactagattt tttttagcag ctgctgattt
     5341 tttctttgta gcagatcttt tcgtctcttg ttttgactta gttgctgttt ttgttaccaa
     5401 ttgacacact tcctataaca gttatggtta aagcttctag cataatatcc cattttttaa
     5461 gaactgtcaa caaaaaattt tctataaata ggaagaaaag ttaagaatag tggtattctg
     5521 aaagaatgtc tctgccatga gtgacacagc tggcaccatc tttgatcagc ttcaaacagc
     5581 ccgccgatgt cccattaaga atattgtcag gtacgacaaa aatatcacgt ccctcttcca
     5641 tagctagctg acaggtaatc aaagagccag agcgctgctt agcctcaaca acaaggacac
     5701 ctcgactaag acctgcgata atacggtttc tttcagggaa atgataagac aaggcggcct
     5761 ctccagcccc atattcactg agcacgagat gacgctgaga taaaaactcc tgtagctggt
     5821 gattttcctt tggatagtag cgatctaggc cagtcccgat aacagctatg gtttgcccac
     5881 ctgctttcaa gcaagcgaga tgagcactgg tatcaatacc tctagcaagc ccgctgacaa
     5941 tgacaaagtg attcttaagc tctttgatga ttttgtaaac agaccgcgtc ccaatttcac
     6001 tggattctct agagccaacg actgccagct taggcttttc taacaggctt aaatcacctt
     6061 gataaaagag taaaacagga ggattataga tttccctcag ggccaatggg tattgcttat
     6121 ctaggataga taagctcgga aactggttga attccttttt taacaaggcg acatttaatt
     6181 gcttgtaggt ctcaataaat aaaactggat ttttgcagca agaaaccact gccatatctc
     6241 taagggatag agacttgtta ttacgctgct ggtagtcaat caggttaaga atatttaaat
     6301 tagttagccc agcctttttt aatttataaa gttcaaaatt attcatcact gtacctctct
     6361 aatgatttat tcgtaaaaaa attaaaaaag ctctgactaa acaaagcttt ttgcaaactc
     6421 ttgaggagct gtacaggatt ccagcaaaaa aatcgaggcc tcctagcctt tgtatgagca
     6481 ttgtagggca gctcatcaca tagcattcca ttgaaaaata ccagaattgt agatccacct
     6541 agtggctatc gtttttgctt tcggcagcta ccttttctca aaatgagatt tttagcgtaa
     6601 gatcattgat tttatcggct caaagctttg ccgatgaatt ggtgtgacac catactggtg
     6661 caatccctgc aggtgctcct tggtcccata gccggcattt ttagcaaagc catagcctgg
     6721 aaaggcctta tcgtaatcaa gcatcaatcg atctctggta accttagcca caatagaggc
     6781 tgcagcgatt gacatagagc tcgcatcgcc ttttataata gcctgttgag gaatagaaac
     6841 ctctagtgtc atggcatcaa tgagcaggta atcaggctta ctcacagagc cctccagctg
     6901 attaatggca gctgtcattg ctaattttgt tgcttcatag atattaaccc ggtcaatggt
     6961 atggttgtca ataattccaa gaccgattcc caacgctttc ttttgaatgg cttggtaaat
     7021 tgcttcatgc ttagctttag gaattttttt agaatcattt agccccttaa tggtgcagcc
     7081 ctttggcagt ataacacagg ctgctacaac tggtccagcc agaggacctc gaccaacctc
     7141 atctatacca gcaatcgctt gaaagccttt ttggtaaagc gcctgttcat acgtcaacat
     7201 cgcctcaagc cgggcttcct cttttaagat agcctctaaa gccctttttc tgctagatac
     7261 agccttttga acgccaagcc gcttatccgc ctttagctct tcaaaaaatg gatcagaaag
     7321 actagaaaca gcttctagac gagctttaat gtctttaata gtcattgctg tcatcatcac
     7381 caacctgatc taaggtgtac tgaccaagtc ttccatcacg aatatccttg atgaataagc
     7441 tgtaaaaacg atcatagtct tccttaaagc caagctgacg tgtcaaggac atgatgattt
     7501 ctggagcgtc agcctctaga tcaatagcct taaaacgctt taataggcga ttaggataat
     7561 acttcttaaa ataattcaat ccaaaaatcg tgacctcgtc cattggcaac agctgatcct
     7621 taatagcccc tgtcagggct aattttaacc caaccaattc gtcttcaaac tttggccata
     7681 agatacccgg agtatccaat atctctagtt ctttattgga ttttagccat tgctgtccct
     7741 tggtcactcc tggcttattg cctactgtgg caattttttt tcccgccaag cgattcatca
     7801 gggttgattt gccagcattt ggaatgccaa taatcatggt tcgtagcgtt tctttttgaa
     7861 tgcctcgttc tcttaagcga cgtagtttat ctgccatcaa ttccttagca gcctcggtga
     7921 cccttttgac cgtagcctgt tccttagcat tgatagctaa tgtcttaatc ccttgcttct
     7981 cataatattg ttgccatttc ttagtatgcg tgttatctgc tagatcagcc ttattaagaa
     8041 gcattagctt gggcttatct ccaacaattt tggtcagcat aggattttga cttgataaag
     8101 gtagcctagc gtctactaaa atcgtcacaa aatcaacatg cttaatattt tcctgtacct
     8161 gtctccttgc cttggacatg tgtccaggaa accattgaat cgtagccatg tgtgtaaaat
     8221 cctttcgtat caagggtttt tagcccctcg tcttttaaaa atcatgcgag tcaccaaaaa
     8281 atcaccaaat attaagcatt atctccagac caagcgatat aattgcaact tgttttggtt
     8341 atttttaatg ccaacaatat caaatgattt ctaatggtat ctggcttata gctattctct
     8401 gctgaataga ttgcctcttc aattttaccc tgtaatctcg ctcagcctgt ctcctgacct
     8461 tgcttttaca tatgaaactg taatattttc cattttacca gttatatgat aaagaaaatc
     8521 aaaatagtcg tagtagaata aattacttta aactattata gcacgatttc ccttatttta
     8581 ctgctaaatt atcctttgta aaagaagata ttaatcgtta taaagaccaa aaaagagaag
     8641 accaaaatga tcccctctag tcttcttttc ggcatatttt accgttattt ggccaacttt
     8701 ccactaatgt gagtaaaatt gtattctaag caagctttac ctattaactt aggagaaaac
     8761 ataatctcta tagctaaaaa taccaaaaaa attatgaatc attatcgcaa actatccata
     8821 gtgatcattt catcagccat ttcccatatt gctggattat gagttgctac gatgattaat
     8881 ctgttagcgt cacgaagaga cagtacaatc tccataatca acttggacgt ggttggatct
     8941 attgaagccg ttggttcatc tgccaaaata aatggcggat tttttaagat gatctttgct
     9001 aaggcaactc gttgtgacta acccccagat agctcaaaaa tgcgtttatc taggttcaga
     9061 taggataaac ctacacgttc taaggcctgt ttctgtctca tcgtttgctc agatttattc
     9121 aatttttgac caatgagacc aagtttgagg ttttcttcaa tcgtttgatt ttcaatcaaa
     9181 ccaaaatttt ggaataggta acccaattca tgacggaaaa aatcactaga tttatagctg
     9241 gctaagtctt tgtctcggta aaaaatagtc ccatgataag gttctaattt ccccatcatg
     9301 ttcatcaagg ttgttttccc gctaccgctt gaaccaatca aagcatagac ttttccaacc
     9361 tcaaatgtca ttgaaagatt agaaaatagc tctcgttctc caaaagattt actcacttgt
     9421 ttaagttcaa tcatgttaac ctcctttcaa aacaagcatg gacatcttgt tttctttctg
     9481 catttgaaca tgtaattgta aaagagatag gccagtgaag agcaacaata ctaagaaagc
     9541 aatcactatc tctacttgaa ggaatacact cgcaacaaat ccgagtaaaa agacacccaa
     9601 ttgagccagg aggtaattcc gatggatttc taaaaatctt agtccagcaa tacgtttgat
     9661 gacaatggca cgtctaaatt cttcaaagta gagcctattc atggtgttaa acaacaagat
     9721 tgaggttgct atcccaagca cagctcccgc aagcattatc caacgttccc tctggatatt
     9781 attcaacaat gtgatgtagt tctggtatcc tgattgcatt tctgagaccc aattttcaat
     9841 gccctgtctc tggataagct cctgggcatc ggacaactga ttaaagagga cataattctg
     9901 taccgcgtca aaccaaaaca tgacggactg aggtccagtt gactggggtg ttacgacaat
     9961 gataatcgga tctttcagaa actgttgata ggaaataggt gtcgtattat acacaaaacg
    10021 gtcttggcct gattccaaat aagccaccgt cgcaatcatt tgctgtcgac catcttgact
    10081 agacatgcga ctagttaagt cgtcttcaaa aacagatttg taatgttctt cctctgaacg
    10141 gagatgctca ggcaagagca agacaaattc ccctactgcg aggtgattca gtttttgttc
    10201 aatagccgta tctacaggga tgttttgacg ctccaagtat tgcggtgtga caataaggac
    10261 attgccattt gggctgtaat cttgccattc tgtagaagtt gtcaagtttt tggaaaagtc
    10321 ttagcctttg ttatcaatac ttgagtagca cctatgtttt tcagattagc ttgctcttgt
    10381 aactgttctg agctattaaa tgctgtcatt tcaacggtga tattttcagt tgattctgcc
    10441 tgcttgttat cttcttttgt tggagattct ggacgtttct caaaataaaa ataattataa
    10501 agctgttgag ccgttactcc tccaccagcc cagccagcaa caggttgacc attcttcaga
    10561 tatagtattg ttggtgttcc tgggattcca actgttttaa ataaaaactc ctgagct
//
LOCUS       DARYLD010000070         9980 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYLD010000070 DARYLD010000000
VERSION     DARYLD010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9980
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU651_001712"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TU651_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL0897681.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TU651_001713"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TU651_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            complement(5931..7601)
                     /locus_tag="TU651_001714"
     CDS             complement(5931..7601)
                     /locus_tag="TU651_001714"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL0897682.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            7799..8491
                     /locus_tag="TU651_001715"
     CDS             7799..8491
                     /locus_tag="TU651_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL0897683.1"
                     /translation="MVMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            8484..9029
                     /gene="coaC"
                     /locus_tag="TU651_001716"
     CDS             8484..9029
                     /gene="coaC"
                     /locus_tag="TU651_001716"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL0897684.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            9086..9658
                     /locus_tag="TU651_001717"
     CDS             9086..9658
                     /locus_tag="TU651_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL0897685.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
BASE COUNT         2914 a         2222 c         1868 g         2976 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt actctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctttat taacaataga tttgtgaaaa attaatttta
     5701 tcatttaata ttaaaagtca gattattaaa aaatatccct accaaagcag aattaaagca
     5761 ttaatgattg tcaatatgac acctatactg gtaaaaaaag attgtgaata acgattaaaa
     5821 tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag attgaagaaa
     5881 ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa tcaaaacaat
     5941 cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat ctttggcaag
     6001 cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc ggtcttaggc
     6061 actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga tggatcgtct
     6121 gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc aaactgggca
     6181 aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc accataaatt
     6241 tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata tagacgctta
     6301 taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc aataccgcca
     6361 tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc tgcacacaat
     6421 tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat agctacaaca
     6481 atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc aaagccagac
     6541 cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc atgcatcttc
     6601 aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag attcggtgtt
     6661 ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc tgtaacagta
     6721 taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc atgagcaata
     6781 ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg aacaaggtta
     6841 ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa atcacgcaca
     6901 tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg agccttcaag
     6961 tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac tgtaatatca
     7021 aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat gacctgccta
     7081 agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg gtcaatacca
     7141 agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt atgagctgtg
     7201 gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg aagaacctga
     7261 gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa agagggctca
     7321 cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa accaatagac
     7381 atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa aatgagctta
     7441 ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc tttgtagtta
     7501 ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc tgtaatcggc
     7561 tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc ttgactctta
     7621 cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt tctatataca
     7681 aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt cagcattgtc
     7741 agtaaaaata attttaatta gtgattttat ttactattct tgctttttct gataaaatat
     7801 ggttatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg ccgttagagg
     7861 gattaccaat cattccactg gccagctagg aaagatagta gctgagacct ttctagcaaa
     7921 gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac agcagcctca
     7981 tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa aagaggaggt
     8041 tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc cagtgtacat
     8101 gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa cagcaagcaa
     8161 taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta aaaaaacacc
     8221 taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg gctttaagct
     8281 attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc tgcataaaaa
     8341 caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc agcacaaggc
     8401 ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc ttgcacaatt
     8461 aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc tcaggtagta
     8521 tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc tatgaggtta
     8581 ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta caggtcttat
     8641 cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt gtcaatcata
     8701 ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc aataccattg
     8761 ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta gccctgcctg
     8821 aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt aacccaatta
     8881 ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca cctaagacag
     8941 cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat gatatggtta
     9001 cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg ctgtattata
     9061 atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa tctctcgtat
     9121 tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt ttttttatat
     9181 ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg cttctatcat
     9241 gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca gtgtgatcac
     9301 aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca caaatggtaa
     9361 tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca ctccttatta
     9421 ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg ttggctcgct
     9481 gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag cctctggtga
     9541 caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg aaatgattgt
     9601 ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa aatcataata
     9661 ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg atatgtgaca
     9721 agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga aaataagtga
     9781 tttttccttt tcaacatgat ataatcccga ctttatcact taaaaacaag taaagaccag
     9841 ctaacccctt gtgtcccaag ggattttgct ggtctttaaa tttattttag tgttgtatat
     9901 ggatttttag cgtaatgttt gagctcttca aacttaacga ttcccttcgc ccattcaatt
     9961 cctagcagtc tgtttaactc
//
LOCUS       DARYLD010000071         9552 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYLD010000071 DARYLD010000000
VERSION     DARYLD010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9552
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..257)
                     /locus_tag="TU651_001718"
     CDS             complement(<1..257)
                     /locus_tag="TU651_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0897686.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNVIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQN"
     gene            complement(257..2239)
                     /locus_tag="TU651_001719"
     CDS             complement(257..2239)
                     /locus_tag="TU651_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897687.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENNDFILASNII
                     YNSLFSSEAIKKINDLSASLNFSINPVEVYQTVKLNIQSLEHQIFLSKILQIIICGIV
                     FLLIYQYAQMFVALKQNDYVKKIILGLSKTRIAISSLNYFIVTITMVILLTFMLTGQV
                     ELLYIGIASLMVLIFSTIMSFRKLSEKYTQILKGDD"
     gene            complement(2306..2611)
                     /locus_tag="TU651_001720"
     CDS             complement(2306..2611)
                     /locus_tag="TU651_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897688.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            complement(2778..3095)
                     /locus_tag="TU651_001721"
     CDS             complement(2778..3095)
                     /locus_tag="TU651_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897689.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(3077..4366)
                     /locus_tag="TU651_001722"
     CDS             complement(3077..4366)
                     /locus_tag="TU651_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897690.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(4368..4811)
                     /locus_tag="TU651_001723"
     CDS             complement(4368..4811)
                     /locus_tag="TU651_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897691.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(5176..8727)
                     /gene="smc"
                     /locus_tag="TU651_001724"
     CDS             complement(5176..8727)
                     /gene="smc"
                     /locus_tag="TU651_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL0897692.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGISKVVSVKLKDTQDLTYLS"
     gene            complement(8728..9420)
                     /locus_tag="TU651_001725"
     CDS             complement(8728..9420)
                     /locus_tag="TU651_001725"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL0897693.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
BASE COUNT         2723 a         2170 c         1648 g         3011 t
ORIGIN      
        1 taattctgga atacataccc aataatagtt ttaaagaaag ttctttcttt tgtcttccaa
       61 atatcctgct catcaactaa aacctttcca ctgtcaattt tttctagtct tcctatgaca
      121 ttaagtagtg tacttttacc tgaaccagag cctccaatca atgcgtagct ttttccagct
      181 tcaaacgtta aatttaaatc tgtgaatatc ttttttgagc cgaatttttt ggtaacattc
      241 aaaacttcaa ttgccattag tcatctcctt ttagaatttg tgtatatttt tcagataatt
      301 ttctaaaact cattattgtt gaaaaaatta aaaccattaa agaagcaatg ccaatatata
      361 atagctctac ttgtcctgtc aacataaatg tcaatagaat aaccattgta atagtcacaa
      421 taaaatagtt gagacttgaa atggctatac gtgttttcga taggcctaaa atgatttttt
      481 taacatagtc attctgtttt aaggcaacaa acatttgagc atactgataa atgagtagaa
      541 atacgattcc acaaataatt atttgcagta tttttgaaag gaaaatttga tgctctaagg
      601 attgaatatt aagttttaca gtttggtaaa cctcgactgg attgattgaa aaattcaaac
      661 tagcactcaa atcgttgatt ttcttaattg cttccgaact aaaaagtgag ttatatatta
      721 tattacttgc caaaataaaa tcgttatttt ctatcatttt atcagtatct agcacaacga
      781 ctatattatc cttactatct gtcacacttt ccaaaggtag attatcttta ttttcaggaa
      841 cactactacc attttcattg aaatagaaaa attcttgccc atcaggaatg acttgcaccg
      901 taaggtcatc ttttgtatag tttgtaccag taaattgttc tgctacaact gtattctcga
      961 ttgatgcctt attctcttta aatttatgag gaatatagat ggttgctatt ttattatcta
     1021 atgattgata gttcgttcca ttaactttat tttgtacctt agcacctgtt tgattaatat
     1081 aaaccagttc cttattaact tctggatgcg ttattccatc actttttaat tgcttagaaa
     1141 aatcttctgt aacatcagaa gctgccatat attctggaac ataggctgaa gatgatttga
     1201 tatatataaa atccagtttt tttaaggctt tagcaatctc tacgtactta gctcctgagt
     1261 catttgcttc ttctccatta gtaacagatt cattttcaat acccaaaaac tctggtcttt
     1321 tccaatcttt tactgcactc catggtttta aatgctttat ctgcatgttt atctttgatt
     1381 gactagcctt tgtttcccgt aaaaagactc ctgaaacaac tattatgata gaaataaccg
     1441 caagccatac gataaaaatg aggctatttt tggccttatt ttttataatt tcaataggtt
     1501 tttcaacctt aatagttagc caaaatagaa caaaggtgat gatgtcaatg atttgaaata
     1561 tgatcaaatt agttaaaagc atagaaaaaa ataacttgga actgtaggtg aaaaaaccac
     1621 tacccaaaaa agaactataa gaaatcatca ataaagcggc cataaccagt tcaaaagtaa
     1681 atgacatgaa ataatctctt cttaggtcgt gtacaggtaa tcctaaagaa cgtcttatca
     1741 ctccttcttt aatctgtctc gctctaacaa caaatagaac aactaataag gttaagtaaa
     1801 ttgaaatcat tagcaataat ctcaacggac cagtaaattg tatcattccc cctatctgcc
     1861 aagggtaagc cagatatatg acttgaagac ctgtagatgt gagcggtttt aaactatttg
     1921 aatctaattt ccctagggta taatacatcc ctgtgattgg tgcagacttt aattgttcat
     1981 gattagtatt atcaaacttg atataagtca actgccccga attttgaact accggtttgt
     2041 aaatggtaac ttttttctct tttgataggt cactaatcgt ttgatacact tcttcattag
     2101 aaagattgct tttcccttga atggagaagg caccatcaat tggtaaaggt attggttttt
     2161 gagtatcatt aatactaacc agaccaatgg cagcaattaa acaaaagaag aatccaacaa
     2221 tgcataattt taatttcata agcacctacc tatatcataa aaggccctat agcattattg
     2281 ggcctttagc tttcataaac catttttaaa atgtaaagta attccaatgt gtatttaatc
     2341 gaacatcatt ccagcttttt gttgcgcttg agtttgccca tccatatttt tgagaatctc
     2401 tatccttaac tgttccccat agattagtta ctgaagattt tgaaccaata ttatttggag
     2461 acttaacata gtcattagaa taaccatagt tatcacttac accataattc cattcatcaa
     2521 taattggata tggagctgga tgcgctgttg ctgcactaac aactctagct gtagcagcag
     2581 atccaaaact taaagtgctt acagcaagca aaactaatgt tttgtcacca atttttcata
     2641 ttagttctca ttggatagat tgttaaaaat atttgaacaa tctaaataat atattattat
     2701 ttattagcat aatatcatat tattatttga attacaagat gctaaattgc aagtaaaagt
     2761 tagtcatcct atagaaatta tccgagtgac ttgttgttca aaattttccc caattttaaa
     2821 aagagatgaa actctgcgtt ggattgatcc tttaagcgac ccaattcatt gaaaaaatct
     2881 gatgcagcat tggcagatag gtctaaacgc ttcaaaaaaa cactcatctt ctggtactca
     2941 gagttgatca aatcatttaa gacatgtctt ctttcagata agctgtcttc acgcttctga
     3001 taggctcttt tctggcgtag aaagtcctgc tcggcatcat ccatctcccg aagcttacga
     3061 taaatagcca cttcctctac aattctgtct gccatgctct aaactctcct gctaactgac
     3121 gatccgtttc aagcttgcta tcaataaccg tctgaatatc tctattcaag ttttcaaagt
     3181 ctgtggccaa ggctgacagc ttgctgacct tggattgagt atagtcctga aagtcttgga
     3241 caaagcggtc atatgtgata ccataagaag caaataaggc ctgcacctca tagtagggca
     3301 gctcatgaaa agagttgaag tcaatcgccg accacacttc cataagcttt gcgtctgcaa
     3361 ccgttttatg atccagagct tcatcagccc cctctcgagc agccttagcc atggacgagc
     3421 ctaggatcat tccctgtgcc gcatctaaaa agagctcctc agaactactg atccccttgc
     3481 cggtagactg ccagtgtttt ttgagctgat tgtagcttga catgctcttt tttgaggcaa
     3541 ggacagttaa ataggcccga ctcacaaggt attgtgttcc aatgagctta ccgtctctat
     3601 ctacaatctg acccttttga ttaaaacgat aagctcctaa atcgtgataa tacaaggggt
     3661 tggctgataa gagcatagca tcgacattcc gagaaatagc taaatcatca gttccaaaat
     3721 aggcaccaaa attgccaatg ccatcaaaat taatgcggaa attattgtac atattgctat
     3781 tagccttaac ccatgtgata gcttcagctg acatgccgcg aacagggtct ggaccattaa
     3841 aggttgttgc tgggatctta tgttctgcgg caactattag tgctagataa gctccgagag
     3901 agtgacctgt ggttgttaag gcagaatgag ggtactttct tttgacctgt tgataaaact
     3961 tttgagcaga tcgtaattgg ttttcggcaa taacaaaatt gccaccatca atattgccgc
     4021 tgactaaatc atcttgattg ccccgaatga gcagctgcca atccgtatca agatctctgg
     4081 aatccgcagc atttgtccct gcataggcaa tcacaacctg agaggtatcg atatcacctt
     4141 taacaatagg ggctacagcc attgcctgca taccgttgtc attggtttta tgggcatcgt
     4201 tgttattgtc ctgaactaag aggactcggt attgtcgttt agtgatagga tcttttacag
     4261 ttttaccagc aacaataaca aggtctccat ttgatttagc tttgctaggt tcgacattat
     4321 aaacctgttt agccaactca ttataactac tatccgatat cgccatatta atcctcctga
     4381 ttgtcctttg aataaatgac agtaacacct acaagagatg ttttattaat cttgtcaatc
     4441 ctatccataa ttcttggttt ggtatcagtt tcaggctttt ccatcttttc tgtatcatca
     4501 tcagtaacaa ttcctcgtat tttctcaaga ctagacaagc catcaaacga aaagcctatt
     4561 tcattttctc catttataat cactatcgtt ccccacgaac ctgtttcccg agaatgtccc
     4621 cagcctgtaa acttaacttc tttaacccct tcatagtcat gaaccagcag cttagcaata
     4681 ctggtttcca agtccctttt ttgttgttcc tctgttcttt tgccattcaa acgaaaaacc
     4741 attatgatcg ctcctattac tattattaag cctagccata gcctttgctt attggtctta
     4801 actgtcatca tgtcctcctt tcactctttt gctatgcgtc cgtcactcta aggaaggcag
     4861 catgactaat tagggtgaaa tcaacgccaa atcttattta tattattctc attttgtaat
     4921 taaattataa tatacagaca tctacttgtc aatatattat gtccttagtt acttttttgg
     4981 tatattttaa tcaaaacaag ccgtactaag ttccaggagc atgtcaaaaa cagcagctta
     5041 ctgctagcca atccttgtgc tttgtccttt ggaaagccaa aaaacctacc atgacgatag
     5101 gtttttttat agcttattct tggttatcat ctgctacatg tagaaataca gctaaaacta
     5161 agctctgtcc tagagttatg acaagtaagt cagatcctgc gtatccttga gcttaacaga
     5221 tactacctta gaaataccag attcttgcat ggtaatccca taaatactgt ctgctgctgc
     5281 cattgtcccc ttgcggtggg taaccacgat aaactgacta tccttgtcaa aacgattgag
     5341 ataatctcca aaacgcttga cattggcctc atcaagggcc gcctcaacct catctaaaat
     5401 cacaaaggga atggtcttaa tgcggataat agcaaataaa agggctagcg ctgataaggc
     5461 tttttctccg ccagacatca cattcaaaga ttgaagcttt ttaccaggcg gttgcactga
     5521 aatatctact ccagcagaaa gcagatcagt ctctgtcaac atcaagtccg ctgagccccc
     5581 gccaaacatc tgcctaaagg tctccttaaa gctatcacga atagcctcaa aggtaaccct
     5641 aaagcgtgcc ttaacctcat ggtccatatt gccaatcgta tctaccaaga gattcttggc
     5701 cttgataagg tcagcccttt gaccatttaa gaaggccaaa cgctcactaa cctcatcaaa
     5761 ttgagcaata gcatcactat tgattgggcc tagggcacga atgctttgct gaacctgctg
     5821 caatttctgt cttgctgctg ccatgtcagt gtcattgatt gggcttgcct gctccttggc
     5881 ctcctctaag cttagctgaa gctcctctga taggcttcta gcgtgctgcc gcaaacgacc
     5941 aataacctgc tctaagtcag cctccagtct tgcctgctga cgaatgaacg cttcattttt
     6001 cttggcttcc ttaagcaatt gagcctctag ctcctccagt ctggcgtcat agtcctcacc
     6061 ttcaaagcgc agctgaatga agcgctcctg agtcttgatc ttgtcttgat tagcctctgt
     6121 cagctgattt tctaggtgag gcaattggtc aatggcctcc tgactaacct gatgtgataa
     6181 aacagtctcc aaattagcta attccttctg accctgagca atcatcgtct ccaagcgacg
     6241 ctggttagct gcttcaaact ttttctcgtt gagcaaatct cgctctttaa gacgagcctg
     6301 agataattcc tggctaagct ggtccttctt ttgcttaatc gtatctttat tttccttaat
     6361 ttgctcaatt tctgacgtta aggctgattt ttcatcagct aggagctgca atgcctcctc
     6421 cagcctcgct ttttctgata ataagcgctc actagactga ccagtctgac ggttgctgag
     6481 aagctctagc agctcttttg agtcagccag cttttctgct agctgctgat aggccaattg
     6541 tgttttttgc tcgaccagtc ttgcttgctc accagccagc ttagtatcag cctgcgcagc
     6601 ctttttagcc ttcaaatcag cctgtacagc agctactgct ttttcagatt ccttgatctg
     6661 ctcagaaagc aaggctaatt ccttctcaat ctgctctagc tctggcttga taaaggttgt
     6721 gctattgtga cgattagtcc cccctgaaaa ggcaccaccg ggacgcagct cggtaccatc
     6781 aagcgttaca atcctgacct tataatgcag ctgcttagct gcctgattag catgatcaat
     6841 ggtatcaaaa atagccgtca cacctaacag gctttgtaca atagcgacca aagagggctc
     6901 ataggtcacc aaagaatcag ctgtgcctaa atagccctga caagccctga gctgcttgag
     6961 agtcacctca gaaagctgac gggccttaat cgttgtcaga ggtaaaaagg tcgcacgccc
     7021 ctgacgatta gcctttaaaa aggctatcgc tcgcttggct gctgcctcat ctgccacgat
     7081 aatatgctga ctactagctc ccaaagcaat ctcaagtgcc gtttgatact gactatcaaa
     7141 ggtcaaatgc tcactaactg ctcctaaaat accatctagc ttaccagcag cctgaagcac
     7201 tgccctaaca cctgcgtaaa attgactatg atttttttgg atagaaacca aactagccct
     7261 acgagcctcc ttggcttttt tctgatccaa caaatcaaaa agccttgtct gtccctgatg
     7321 ataatcctgc tccaaggcct caactgtctt tgctagctct tgataatcag ctaggagctg
     7381 ctcaagtctt gattgactag cttgataagc caaaagagca gtctgggtgt cctgactgag
     7441 ctgattgacc ttctcttgta ggacttggta ttcctgcgcc tgactggctt tcgcctgact
     7501 ttccttatcc agctgcgcta caatagcggt taattggttt gacacatcag cctcttgctg
     7561 gagcagacca acaaaatcct cacgaagagc ctcaagcagc tgatctggat cgctagaaaa
     7621 tcgctcaagc tcctgagaaa gctcgctgac cttggtatta aactcagcta aggcttgatg
     7681 gatttcatct agctgacgac tcttttgctg atgctcctgt tgaaaggcaa gcaattgctc
     7741 ctgagcctgc tgcctgcgct gactggcttc tgttttcttt tcctgctttt gactaaggtc
     7801 cagcttgatg aggtcaatct gtcgctccag atctgatatg acctttgtca attctagcaa
     7861 atcagcctgc gtctgctcag ctacagcaga gagcttttgc cgcttggttt ttagacggtg
     7921 attttccgcc tctagactct gacgcttcct atgataggcc gctagatcct cacgaagagc
     7981 tactaaggcc ttttcttgag cctcctgctc catgcggtct tgctctatat ccttgaccaa
     8041 aatatccagc tgcagctgct tacgatcagc atctaaggct aaaaattgcc tagcagtttt
     8101 cgcctgtctt tctagaggac cagcttgatg ctcaagctca tagataatat cgtctaagcg
     8161 gtcaagatta tcttgagttt ggtttagctt agtttgcgtc tccttcttgc gggtcttgta
     8221 tttcaaaact ccagctgcct cttcaaagat ggcccgtctt tcctctggct tactattgaa
     8281 aatctcctca acacgacctt gagaaataat agagaacgaa tcgcgcccta gtcctgtatc
     8341 cataaacagc tcgtgaatat ctcttagcct aacttttttg ccatcaatca gataatcact
     8401 gtcgccattg cgatagatat gcctctccac acgaatctct ttctgagcat tcttaataaa
     8461 ggcatctgaa ttatccaaga caacagccac ctctgcataa ttcaagggac tccgatgctc
     8521 agttccagca aagatcacat ctggcatctt gccaccgcgc aggcttttgg cactggcctc
     8581 accaagtgcc caacgaaggc tttctgtcac attacttttt ccagagccat ttggccctac
     8641 aacagctgtg acccccttat caaagataat cttggtctta tctgcaaaag acttaaagcc
     8701 ctgcatttgt atttctttta aaaacattta gacctcacta agttgggcca gggcattttt
     8761 agcagcgtcc tgctctgcca gttttttaga tctacctgtc cccttgctaa gatgatcctc
     8821 accaaccaat acagctacct caaattgctt agcatgagct ggtccagtct cgctaatcac
     8881 ctgataatca atcacaacat cacccttagc ctgtaacaac tcctgcaagc aggttttata
     8941 atccttgacc ttctcaaaag ttccctgctc aacctgtgga atcataacct gatttaaaaa
     9001 gcgacgaacc tcttcaatgc ctttatccaa aagaagagca cccaaaaaag cctcgaacaa
     9061 atcgcctaaa atcgtatcac gatgacggcc tcctgatttt tcctcgcccc tgccaagctt
     9121 aatataagca tcaaacgaac aatagcgtga aaagcctgct aagctttcct ctctgacaat
     9181 cgttgatctg agttttgaca tatcaccctc agtctgctta ggatacttgg caaagaggta
     9241 ttctgaaata attaactgta gaacggcgtc tcctaaaaat tccaaacgct cattatgtga
     9301 aatgtttagg aggcgatgct cattagcata agaggtatgt gtaaaggcag tctctagtaa
     9361 tcttttatca tcaaaacgga tattaaaaga gttttccagc agggcctcaa gctttttcat
     9421 catgacaaat ctccttttct aatgtcctta taaaccattc tattataaca aaaatccact
     9481 tgaaaggctt atcacaagtg gatttttcag aaatattgta ccaaataggc acgagctatt
     9541 gactgctgct at
//
LOCUS       DARYLD010000072         9426 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYLD010000072 DARYLD010000000
VERSION     DARYLD010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9426
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..484
                     /gene="glmU"
                     /locus_tag="TU651_001726"
     CDS             <1..484
                     /gene="glmU"
                     /locus_tag="TU651_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL0897694.1"
                     /translation="SRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVHIG
                     NFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHAFI
                     GSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQAK
                     "
     gene            515..1069
                     /locus_tag="TU651_001727"
     CDS             515..1069
                     /locus_tag="TU651_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL0897695.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            1069..1317
                     /locus_tag="TU651_001728"
     CDS             1069..1317
                     /locus_tag="TU651_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897696.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            1341..2042
                     /locus_tag="TU651_001729"
     CDS             1341..2042
                     /locus_tag="TU651_001729"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL0897697.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(2098..2745)
                     /locus_tag="TU651_001730"
     CDS             complement(2098..2745)
                     /locus_tag="TU651_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL0897698.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            2891..3823
                     /locus_tag="TU651_001731"
     CDS             2891..3823
                     /locus_tag="TU651_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL0897699.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            3883..4608
                     /locus_tag="TU651_001732"
     CDS             3883..4608
                     /locus_tag="TU651_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL0897700.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            4609..5442
                     /locus_tag="TU651_001733"
     CDS             4609..5442
                     /locus_tag="TU651_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL0897701.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(5598..6404)
                     /locus_tag="TU651_001734"
     CDS             complement(5598..6404)
                     /locus_tag="TU651_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL0897702.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(6491..6664)
                     /locus_tag="TU651_001735"
     CDS             complement(6491..6664)
                     /locus_tag="TU651_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897703.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            6784..9183
                     /locus_tag="TU651_001736"
     CDS             6784..9183
                     /locus_tag="TU651_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL0897704.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
BASE COUNT         2607 a         1795 c         2207 g         2817 t
ORIGIN      
        1 ttcgaggctt ggtgagggcg tagtggtgag ccagtcagtg attgaggatt cagtcctagc
       61 agatggtgtg acagtagggc cctatgcgca cattcgccca gactcccagc tcgatgagag
      121 cgttcatatt gggaactttg tagaggttaa ggggtctcat ctaggggcca ataccaaggc
      181 agggcatttg acttacctgg ggaatgccga gattggctca gaggttaata ttggtgcagg
      241 aagcattacg gttaattatg atggtcaacg gaaataccag acagtgattg gcgatcacgc
      301 ttttattggg agtcattcga ctttgatagc tccagtagag gttggggaga atgctttaac
      361 agccgcaggg tctacgatag cccagtcagt gccggcagac agtgtggcta tagggcgcag
      421 ccgtcaggtg gtgaaggagg gctatgccaa gaggctgcca catcacccaa atcaagcaaa
      481 gtaaaatgat ggagagaaag caaggagatc agacatggat tttgaagaaa aaacgattaa
      541 aaggcaagag atttttgatg gtcacatttt caaagttgcg gtagatgatg tccaattgcc
      601 aaacggccta ggtcaggcta agcgcgaatt gatttttcat cgcggtgcag tcgctatatt
      661 ggctgtaacg ccagagcgta agctgttaat tgtcaagcag taccgtaagg ctatcgaagc
      721 gatttcttat gaaattcctg ctggaaaact agaggtcggt gaggccaact cagcattaga
      781 agcagcagca cgagagctgg aggaagaaac cgcctattct ggtgatttgc gtcttattca
      841 cgagttttat acagcgattg gtttttgtaa tgaaaaaatt aagctgtact tggcgacaga
      901 cctgcagaga gttgccaatc ctagaccaca ggacgcagat gaggtgattg agcttcttga
      961 gctgagctat caagaatgta tggatctagt ggcacaagga aagcttgtcg atgctaaaac
     1021 catcattgcc ctgcaatatt acgcccttca ttttggaggt gatgtgtaat gggcaagccc
     1081 ttgctgactg atgacattat cgaaaaggct cagcgcggag aacagtttga gcctgacgat
     1141 tatgcagatt ttgaaaccaa aatcatgacc tttgaggata agcatactga tcgtatttac
     1201 aaaagtcgca gaattgaaaa tgcaaagcgc agtcgctttc aatcgcggtt aaatctgatt
     1261 ctcttagcgg tgcttgtctt gattgctctc ttggtttatg cggtctttaa tttatagaaa
     1321 aaaacaaata aggatatcat atgaaaattg gaattattgc ggctatggaa gaggagctgc
     1381 ggtttttatt ggagcagctc cacgatagtc aagagcatca ggtgctttcc aatacctact
     1441 atacaggtcg tcttggtcgc catgagctcg tcttagtcca atctggtgtt ggaaaggtca
     1501 tgtcagcgat gacagttgcg atgctagcag agcattttca ggctgacgct attataaata
     1561 caggatcggc tggagcaata gctagtggct tggctattgg tgatgttgtt gttgctgatc
     1621 gcttggtgta tcatgatgtg gacgtgacgg cctttggcta tgactatggt caaatggctg
     1681 cgcagcccct ttactttgac agtgatagca agctggttga gacctttaag caggtgcttg
     1741 atcaggaaaa gaccaatagt cggattggcc tgattgcaac aggagatagc tttattgccg
     1801 gccaagacag tattgatacc attaaagcac atttcccaga gaccttagca gtggaaatgg
     1861 agggagcagc agtggcacag gcagctcaag ctgctggcaa gccatttatt gttgttaggg
     1921 cgatgagtga cacagcggcc cacgatgcta atatgacctt cgatcagttt attgttgagg
     1981 ctggaaaaaa atcagccaag gtcttgatag cctttttaga ggccttacct gataaaaaat
     2041 gatgaccaaa aaaacctgat agcctgtggt gacagcaaat atcaggtctt tttttattta
     2101 aatagcagta acaaagagct gcttggcgat gttttcagga atgatcaatt ccttatctgc
     2161 ataagtgatg gtataggttt ttgcgaagtc atctatttga atcagtctaa actcactatt
     2221 gatcgtcagc tggtgtgctt ctaggtactg gataagctca aagtgatcat gcaccctgct
     2281 caaacgaaaa attcccagct ctttaatagt attaagcgtt gttttgttga tttcgattag
     2341 tggctgctgg cggcgtggaa ttgtccctcc atgagggcaa aaagtaggat agccaagggt
     2401 tttatccaag cgatcaataa acatatctga cacagtatgc tctagtacct cagcctcttg
     2461 gtgcacctct ctagcagtat agcccagttg atggatcaag aaaacctcca tcaatcggtg
     2521 cttacgataa agatttgcca ctaagcgctg cccttgctct gttagataat agccgcaggt
     2581 cttatccttt acaatccagc cttgtgcgat cattttctta atcatttctg acacagcggg
     2641 tgcagaaacc ttcattctct ctgcaaccat tttgttagaa attttaatgt tttgctctcc
     2701 gatttcataa atacatttca aatagtcttc tttattaggc gtcatgtcta aaagcctttc
     2761 tcttatttat aatgattatt atatcagatt atttcataaa aatcttgaca aaggcctaaa
     2821 aaaaagttat gctaatagca taattaacta tacttaatta attaaataat agatcctaag
     2881 gagataactg atgaaaaaga aacttagcct cgccttgagt gcttttttgg ctgttttcat
     2941 gctggttgcc tgctctaatg gtggaaacaa ggaagctaag agtgacaagc tcaaggttgt
     3001 ggttaccaat tccattattg ctgacatgac taaaaatatt gcaggtgaca agattgactt
     3061 gcacagcatt gtgccgattg gtcaagatcc gcatgagtat gagccattgc cagaagacgt
     3121 tgagaagacc agcaatgccg atcttattct ctataacggt attaaccttg aagacggcgg
     3181 acaggcttgg tttacaaagc ttgtaaaaaa tgctaagaag gaaaaggaca aggactactt
     3241 cgctgtatct gatggtattg atgtgattta cctagaaggt gaaagtgaaa aaggcaagga
     3301 agaccctcat gcttggttga atcttgaaaa tggggttatc tattcaaaaa atattgcaaa
     3361 gcaattgatc gctaaagacc ctaaaaacaa ggaaacctat gaaaacaacc taaaagctta
     3421 cgttgagaag ctagagaagc ttgataagga agcaaaatca aaatttgatg ctattgctga
     3481 caataaaaag ctaatcgtca caagtgaagg ctgcttcaaa tacttctcaa aagcttacgg
     3541 tgtcccatca gcctacatct gggaaatcaa cactgaagaa gaaggaactc cggatcaaat
     3601 ttcatcattg atcgaaaaat tgaaagacgt taagccatca gcgctttttg ttgagtcaag
     3661 tgttgacaga cgtccaatgg agactgtttc taaggacagt ggtattccga tctatgcaga
     3721 aatctttact gactctgtag ccaaaaaagg ccaagatgga gacagctact atgccatgat
     3781 gaaatggaac cttgataaaa tttctgaagg cttagcaaaa taatataaca ataaagcaca
     3841 gcagcttctg gtgttgtgct ttgtttgtat taaggagaaa aaatgattga tacgcaaaat
     3901 ctttcggtta gctataacgg taacgtaaaa gccttagaca atatctcact acaaatcaaa
     3961 ggaccagcta tcgttgggat tatcgggcca aatggtgcag gaaaatcaac cttgatgaag
     4021 gctatgctca atcttttaga ttatagtggc caagtaactg ttgatcaaaa ggacggtcga
     4081 aggctggggc atacgattgc ttatgtagag cagcgcagca tgattgacta caactttcca
     4141 attacggtga aggagtgcgt ctcattaggg acctacacta ggctagggct ttttcgtcgt
     4201 gtcggaaaaa aagaatatga tcaggttgac cagctgctag agcaggttgg gcttgctggc
     4261 tttggtaatc gtccgataaa atctctttct ggtggtcagt ttcagcgtat gctagtagct
     4321 agatgcttga ttcaggagtc agactatatt tttcttgatg agccctttgt tgggattgat
     4381 tcggttagtg aaaaaatcat cattgacctg ctcaaggact tgaaaaaagc aggcaaaacg
     4441 attttaattg ttcatcacga tttaagcaag gtagagcatt actttgatga gttagtggta
     4501 ttgaacaaag agctgatcgc ttatggatct gttgatgagg tgttcactgt tgaaacccta
     4561 tcaaaggcct atggtgatca tctattctta ggaaagggaa tgttttaaat gtatttgaag
     4621 ttttttgagg gcctgatgtc ctatcatttt ttacaaaatg cccttattac agccgttgtt
     4681 attggtattg tatcaggagc agtaggctgc tttattatcc ttaggtccat gtcattaatg
     4741 ggtgatgcga tttctcacgc tgttttgcca ggagtagcct tgtcctttat tttagggatt
     4801 aatttttttg taggggctat tgtctttggc ttgctagcct ctgttatcat tacctacatc
     4861 aaggaaaact ctgttatcaa gggagacaca gcaataggga taacctttag ctcttttctt
     4921 gccttagggg ttattctgat tgggattgct aatagctcaa cggatctttt tcatatcctc
     4981 tttggaaata tcctagcagt gcaagacagt gacaaatgga ttacgatcat tgtttcggtt
     5041 tttgttttgg ctattattgt cctcttcttt aaggaattac tcattacctc ctttgatcct
     5101 gtgctagcaa ggtctatggg aatgaaggtc actgcttatc attatctgtt gatgattttg
     5161 ttgaccttgg tttcggtgac tgctatgcaa agtgttggta ccattttgat tgtggcgatg
     5221 ctgattacgc cagcggctac agcgtatttg tatgctaaca gcctaaaggt aatgctggtt
     5281 atctcctcat gcttgggagc tatgacctct gtgttggggc tctatttggg ctacaccttt
     5341 aatattgcag caggctcaag cattgttttg acctcggctg tggtgtttct gattagcttc
     5401 tttgtttcgc ctaagcaggg ctactttaaa aagcattcct agtaaaccat agctggctgt
     5461 gaatggatag ctgctaatga tatgatcaat aggctagctt ctttatttaa ttgatagcaa
     5521 aaaatcacga ccagctcttg aatcggtggc ttttccgata aggagctggt cgttttattg
     5581 ttgttgtagc ttagaggcta ttttttaaag gagtaatcct taacaatgtc aatagcatta
     5641 atagtgatgt tctctattgg tttgtcattt gggccgactg ggctggcagc tattttatca
     5701 acgatatcca taccctcaat aacctgacca aaaacggtat agccaccatc taggctagga
     5761 ttaccccctt cttcgtagga gtcaatgatt ggcttagagt aattatcaat tgataaggcc
     5821 ttggcttggt tgagcttgct ttgattgatg aagaactggc tgccattagt atctgcaccg
     5881 gcatttgcca tagcaagagc ccctcgaatg ttatataaaa atggtgagat ttcattagca
     5941 aagccttgtc ccgcatcttt tttgctgtcc ttgcccttcc aaatggattc tccgccagat
     6001 ccatctccct ttggatcacc ggtttgaatc ataaagttat taatcacccg atggaacaaa
     6061 agtttgtcgt aatagccttc cttggcgtgt gttaaaaagt tttcaacagc aagcggtgca
     6121 tacttgggga agagcttgag ggtgatatcg ccctgattag ttttgataat gaccttagct
     6181 tcgtctttgt cgacttcttt atttaattgt ggaaactgat cagcgtcagc cttgagtgct
     6241 tttttgattt ttgcttcata agcctttgct gctgtctcgc tttcctctct agcgattttt
     6301 tcatcgacgt attcatcacc tttaatagca cgatcaatgg actcacagcc acttaagcta
     6361 agcaaagcaa gaccgattaa gccaaaagat agtagttttt tcatgtgtac tccttagaac
     6421 aatttctttt attttaacat aaaatgactt ggaaaataaa gctaaagggc attgagacga
     6481 agtctatttt ttaactattt ctaagcttct ctaagtcctc ctgagaaacc ttgaaggtga
     6541 cttgcccggt ctgcatatca acgatagcct tgacttcaac tcctttggga attagcttgc
     6601 catgccccat atcaatttgc aggggaagct taccataggt caaggtgtta aattcttttt
     6661 ccatcttcaa ctcctatttg ttcttatgat tgacattata gcataaaatc aagcagcttc
     6721 atctatttat tgagaatttt aatgtcatct ttcataacga ttaaaaaatg ttataataag
     6781 gctatggcta gaagaactca acgacaaaaa aatcccccta agagacgttt aacaaaggca
     6841 gagcttgaaa agcaaaaggc tattaagaga atgattgctt ctttctcctg cgctttattg
     6901 cttgtttttg ccatgcttcg cttaggtgcg cttggggtta ccttatataa tcttattcgc
     6961 tttatggttg gcgacttagc caatctcttg atgttggcgg tcctttttta cctctttttc
     7021 ttcaagtggc tcaggcaaaa agatggcctt atcgctggct ttatcatctt gtttttaggg
     7081 cttctggttg aatggcatgc ctatcttttc tcattgcctc agctagctca tcaggctatt
     7141 gttgctggga ctatccagct aatcaccaat gacctgctag cctttaaggt tagcgagttt
     7201 gttggtggtg gtatgcttgg ggccatgctg tacaagccta tttccttctt gttttctaat
     7261 attggctctt attttattgg ttttttgttt atcctgctgg gcttgttttt aatgacccct
     7321 tgggatattt atgacgtcag tcattttgtt aagacgcttt ttgaaaagct atccctggcc
     7381 tatcaagaaa acaaggaaaa gcggtttgtt gagcgagaaa agcaacgatt gctggctgaa
     7441 gaggagcgtc tagcaagaga ggccttggag gagcaagaat atctggccaa tcaagcgatt
     7501 aatcctgaga caggtgagct tttagcagag ccagaagacc tattgatgga gatggctgat
     7561 cagaaggagt ctgaagcatt ttttgagccg gaaattctgg cctatgactc acaccctgct
     7621 gatgatgagc ctgaggcatt tggagatgaa gaggagtctg taccagaagc ccctctaacg
     7681 ggtgcttcag caatcgcagg agaggcgccg ctgtcagatg atgaggagct gtcagtggag
     7741 gtcgatttca cgccaaagac caatctgctt tacaagctgc cgacgataga gctgtttgct
     7801 gctgataagc ctaaaaatca attcaaggaa aagtaccttg ttcgtcaaaa tatcaaggta
     7861 ttagaggata ccttcagaag ctttggaatt gacgtcaagg tggagcgggc agagattggg
     7921 ccatctgtaa ctaaatacga ggttaagccg gctgttggtg ttcgtgtgaa tcgcatttcc
     7981 aatttagctg atgacttggc cttggccttg gcagccaagg acgtacggat tgaagctccg
     8041 atccctggca aatcccttgt gggtatagag gtaccaaatt cagaggttgc aacggtttct
     8101 ttccgcgagc tttgggagca atccaacaca tctgatgaca aattattgga aattcctctt
     8161 ggtaaggctg tcaacggtag tgccagaagc tttgatttga cccgcatgcc tcatttgctg
     8221 gtggctggct caacaggatc agggaaatct gttgcagtca acggtattat ctccagtatt
     8281 ttaatgaagg ctagaccgga tcaggtcaaa ttcctaatgg tcgatccgaa aatggttgag
     8341 ctgtctgttt ataatgacat tcctcacctg ttaatcccgg tggtcaccaa ccctcgtaaa
     8401 gcaagcaaag cgcttcagaa ggttgttgat gagatggaaa atcgctatga gctgttcagt
     8461 aaggtcggtg tccgaaatat tgcaggctac aatgccaagg ttgaagccta caacaagcaa
     8521 tctgagcaaa agcaaatccc tttgccgatg attgttgtta ttgttgatga gctagctgat
     8581 ttgatgatgg tggctagtaa ggaggttgag gatgctatta ttcgtcttgg gcaaaaggcg
     8641 cgtgcagcag gtatccatat gattttagct actcagagac cttctgttga tgttatttct
     8701 ggattgatta aggctaatgt tccatcacgt attgcctttg cggtttcatc aggaacagat
     8761 agtcgcacca ttcttgatga aaatggcgct gaaaagctgc ttggtcgcgg ggacatgctc
     8821 tttaagccga ttgatgagaa tcaccctgtg cgtctgcaag gctcctttat ttcagatgat
     8881 gatgttgagc gcattgttag ctttatcaag gagcaggcag aggctgatta tgatgattat
     8941 tttgatccgg gtgaggttag tgactctgat tatggcagca gcggagctcc tgagggtgat
     9001 cccctttttg aggaagcaaa ggctcttgta ttggaaacgc aaaaggcaag cgcctcgatg
     9061 ctccaaaggc gtctatcggt tggctttaac cgagcaactc gactaatgga cgaattagaa
     9121 gaggccggtg tcattggtcc agctgagggg actaagccaa gaaaggtact gcaaaccaat
     9181 taaaaaagag ctcatctaaa ggctcatcat aaaacaaacc cgtaccaagc taagcttaac
     9241 catgtggctt gatacgggtt tttgatatgc tgctttgaaa aagtcccact caagcagaaa
     9301 actcaaagac agcttcattt tgagtgatag tgctagagct aattggcaga tctaatctgc
     9361 taagtcaata tgtccataat accttaatat atagagagtt ttaaaaaaag attagctaat
     9421 atcaca
//
LOCUS       DARYLD010000073         9408 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYLD010000073 DARYLD010000000
VERSION     DARYLD010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9408
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(7..369)
                     /locus_tag="TU651_001737"
     CDS             complement(7..369)
                     /locus_tag="TU651_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0897705.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TU651_001738"
     CDS             complement(347..781)
                     /locus_tag="TU651_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0897706.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TU651_001739"
     CDS             complement(768..1058)
                     /locus_tag="TU651_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL0897707.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TU651_001740"
     CDS             complement(1015..1440)
                     /locus_tag="TU651_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL0897708.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TU651_001741"
     CDS             complement(1418..1741)
                     /locus_tag="TU651_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL0897709.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TU651_001742"
     CDS             complement(1742..2728)
                     /locus_tag="TU651_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL0897710.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU651_001743"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TU651_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL0897711.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TU651_001744"
     CDS             complement(3829..4476)
                     /locus_tag="TU651_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897712.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TU651_001745"
     CDS             complement(4478..6481)
                     /locus_tag="TU651_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL0897713.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TU651_001746"
     CDS             complement(7018..7383)
                     /locus_tag="TU651_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL0897714.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TU651_001747"
     CDS             complement(7444..8490)
                     /locus_tag="TU651_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL0897715.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(9054..>9408)
                     /locus_tag="TU651_001748"
     CDS             complement(9054..>9408)
                     /locus_tag="TU651_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897716.1"
                     /translation="LSSIDLDRQEAIFTENSVTIRDIFSPRSFTGVNKIVFTWKGYDL
                     YLDSTNANRLSALGWGSTALSGLIPDPIVSKVLAAALGVVSASISYANAAGRGVIVAF
                     VGTFPRGVIHWVASQ"
BASE COUNT         2979 a         2128 c         1713 g         2588 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agcaataatg acataattca ataaaagaca taattaatca caacttgatt gtctttctaa
     8881 caaatccatt ccctgcctgg atcattagta tacgaaaaaa atgataggta aaactatacc
     8941 caataggcag aaaaaaactt tccaaaaaat agtattattt ttaaataatt tatcaacaaa
     9001 caccaataat atcaaattaa ttgctaaaca cagtattttt aaatataatg ctatcattgt
     9061 gaagccaccc aatgtatcac acctcttgga aaagttccta caaaggcaac aattactcct
     9121 cttcctgcag cattagcata agatattgat gcagacacaa ctcctaaagc ggctgcaagt
     9181 accttagata ctatagggtc tggaataaga cctgacaaag cagttgatcc ccagcctagt
     9241 gcagataatc tattcgcatt ggtactatct aaataaagat catagccttt ccaagtaaaa
     9301 acaattttat ttaccccagt aaatgatcta ggactaaata tatctcttat agtaacagaa
     9361 ttttcagtaa aaattgcttc ttgtctatct aaatcaatag aagataaa
//
LOCUS       DARYLD010000074         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYLD010000074 DARYLD010000000
VERSION     DARYLD010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            101..1027
                     /locus_tag="TU651_001749"
     CDS             101..1027
                     /locus_tag="TU651_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0897717.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TU651_001750"
     CDS             1135..2421
                     /locus_tag="TU651_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL0897718.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TU651_001751"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TU651_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TU651_001752"
     CDS             2977..3189
                     /locus_tag="TU651_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL0897719.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TU651_001753"
     CDS             complement(4085..4225)
                     /locus_tag="TU651_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897720.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU651_001754"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TU651_001754"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL0897721.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TU651_001755"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TU651_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TU651_001756"
     CDS             8213..9118
                     /locus_tag="TU651_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL0897722.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2532 a         1730 c         2098 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atgggagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYLD010000075         9137 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYLD010000075 DARYLD010000000
VERSION     DARYLD010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9137
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            95..340
                     /locus_tag="TU651_001757"
     CDS             95..340
                     /locus_tag="TU651_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL0897723.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            388..969
                     /gene="amaP"
                     /locus_tag="TU651_001758"
     CDS             388..969
                     /gene="amaP"
                     /locus_tag="TU651_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL0897724.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            979..1167
                     /locus_tag="TU651_001759"
     CDS             979..1167
                     /locus_tag="TU651_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL0897725.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1180..1719
                     /locus_tag="TU651_001760"
     CDS             1180..1719
                     /locus_tag="TU651_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0897726.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1757..1954
                     /locus_tag="TU651_001761"
     CDS             1757..1954
                     /locus_tag="TU651_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL0897727.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1964..2452
                     /locus_tag="TU651_001762"
     CDS             1964..2452
                     /locus_tag="TU651_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0897728.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2608..3249
                     /locus_tag="TU651_001763"
     CDS             2608..3249
                     /locus_tag="TU651_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL0897729.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3366..3914)
                     /locus_tag="TU651_001764"
     CDS             complement(3366..3914)
                     /locus_tag="TU651_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL0897730.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            4037..4738
                     /locus_tag="TU651_001765"
     CDS             4037..4738
                     /locus_tag="TU651_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897731.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4750..7389
                     /locus_tag="TU651_001766"
     CDS             4750..7389
                     /locus_tag="TU651_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL0897732.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILTSHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7465..8061
                     /locus_tag="TU651_001767"
     CDS             7465..8061
                     /locus_tag="TU651_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL0897733.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            8071..9033
                     /locus_tag="TU651_001768"
     CDS             8071..9033
                     /locus_tag="TU651_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL0897734.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         2640 a         1587 c         2132 g         2778 t
ORIGIN      
        1 tgtatcaaaa aaataactag caattttata tttaatttat gtagtcactt taaagagtga
       61 acaaagtagt tttattgaat tgaggagatt tattatggga attatttgga cattaattgt
      121 gggtgcactt atcggtgcta ttgccggtgc gcttactaaa aaaggcggat caatgggctg
      181 gattgccaat atcgctgcag gacttattgg atcatacgtt ggtcaagctt tgtttggcag
      241 ctggggtcta acattagctg gcatggcact tttcccatca atcattggtg ctgttatcgt
      301 tgttatcatt acttcttttg tactaaataa atcaaactaa gggcatttct atcattatag
      361 agatggttga gtaggaaaga ggtttttatg tcgaaatttt taaaaattag ctatagtctc
      421 attggcttag tcctattgac ggtctttggt ggcgtgatag ccataactgg agattatatt
      481 aggctaccta ttggctatca atggcttcac tgggatatga attggcttcc taaattccta
      541 aatccggcct tatattacta ttacttttgg gcagctatcg ctttatttct aataacagtg
      601 ctgatccttc ttgtgattat cttttatcca cgcacctata ctgagattca gctggctaag
      661 gataaaggaa ccctgctttt gaaagggtct gctattgaag gctatgtagc agctgctatt
      721 aaagcagcag ggcttatgtc aagcccaaga gttaccgcta agctgtacaa gcgtaaattt
      781 aaggttaatg tcagtggaca attagcttct cgcgtagctg tcactgagca gctaaatggc
      841 attaaagaag gaattgagac tggtttaaca gaattctttg gtattaatcg acctgtccat
      901 ttcaaggttt atgtcaagga tattgctgat gctaagcaaa agcatagctc taagagacgt
      961 gtagaatagg agattatcat ggcattttat gaacggttta aataccctat tattggtggt
     1021 ctgatagggc tgatagctgc tgtattactg atgacctttg ggttatttaa aacactgctg
     1081 gcaattattt tcattatttt aggagtatat ggcggcctgt atgccaaaaa gacaggtatt
     1141 atcgatcaat tgatcaaacg taactaaagg agatttatca tgactgaaac ttacattaaa
     1201 aacacaactc ataaagaacc aacttcagct gttcgtggcg aattgaccta tgatgacaag
     1261 gtcattgaaa agatcgttgg cttggctctt gaaaacattg atggcctact aggtgttaat
     1321 ggtggctttt tggccaatct aaaagacaag cttgttaata gtgattctgt tcgtgatggg
     1381 gttaatgttg aggttggtaa aaaagaggtt gctgttgatt tagacattgt agcagaatac
     1441 caaaagcatg ttccaaccat ttttgatgcg attaaatctg tcgtagaaaa tgaagtcaag
     1501 agaatgacag atttagaggt gattgaggtt aatgttaagg ttgttgacat taaaaccaag
     1561 gagcaatttg aagctgataa ggtcagccta caggataagg tgactgaggt agctcgctca
     1621 acctctgaat ttacaagcaa gcaggtagac aatgttaagg catctgtagg tgcaggtgta
     1681 gaaaaggttc aagagcaaac tgagccacgc gttaagtaag ctaggctgtc aaacgataga
     1741 aatagaggaa atcataatgt cagaagaaaa ggtaaatgca aaattggagc aagcaggcgg
     1801 taaaatcaaa gaagcctttg gaaaggtgac tggtgataaa tccttagaaa ccgaaggtaa
     1861 ggttgatcaa gcagccagca aaatcaaaga agtagctgct gatgctaagg acgctgtcaa
     1921 gggctttgtt aagggcctta agcaagataa ataaggagtt gtaatgaaag caaaggacat
     1981 aaaaagtacg ttgacctacg atgataaggt cattgaaaaa atcgttggac atgctttaga
     2041 gaaggtcagt ggcttattag cagtcaatgg tggctttttc tcaaatatca aaaataacct
     2101 agtgaatagt gactctgttc gtgatggggt gtctgttgag gttggcagca aggaagtggc
     2161 tgttgactta gatattgttg ttgaatatgg taaggatatt ccagcaattg ttgagtctat
     2221 caaggctatt gtttttcaaa atgtcgatag catgacacat ttgagggtcg ttgaagtaaa
     2281 tgtgaacgtt gttgatatta gaaccaaaga agagcatgag gctgctagcg tcactgttca
     2341 agacaggcta acagacgcgg cctcagcaac ctctcaattt gtagctgagc aagcagacaa
     2401 ggtaaaagaa actgtctcta aaaccacaga taataacgag acagtagaat aaaacacaac
     2461 aactaaaact cctgttaatg acatattgtg ggctggtgtg atgaccagct ctttttatca
     2521 gtgcttgaac aatgttatgc tattgtattc tctgtgaaaa tgtgatttaa tgggaatggt
     2581 atcatttgtt aaaaaggagt aattatcatg actagtaata agagagagat tactaattcc
     2641 aagtatcaaa agattgccat ttcagttgct gaaaggattg ccaatggcga atatgaagtg
     2701 ggagaaaagc taaagtctag gacaaccatt gcttcgacct ttaaagtttc gcctgaaact
     2761 gctagaaagg gtctgaatat tttagctgat ctgaagattt tgaccttaaa gcatgggagt
     2821 ggcgccattg tcttgtctaa ggaaaaggct attgattttc tgaaccaata cgaatccacc
     2881 cattctatcg ctgtcatcaa agaaaatatt cgccataata ttcgtgagca ggaaaaggca
     2941 atggagcatt taacagtgct tgttaatgag tttctgatgc aaagccaatc aatcagcaag
     3001 caatacccgc tggcacctta cgaaattatt tgtagtcagg attcagagca ttttggccaa
     3061 tccattggtg atttgaacat ttggcatcaa acgggagcga cgattgtagc tattgagcat
     3121 gatggccaat tcattgtttc tcccggtcct tacgctgtta tcgaaaaagg tgatcatatt
     3181 tactttgtcg gtaatgagga cgtgatttct agaatgaaaa ccttttttaa tgttagaaag
     3241 ggtctgtaat cacaaaaaaa cacagagctg ctttaaggtg atggtgatat cacgatgaag
     3301 tgtctctgtg tttttgtgtt atcaggctaa ggcttctaag tagcttatag ctctgattga
     3361 agcccctaga ttactttttc aaagccaaca gttttcagga taatagctgt catgtcatcg
     3421 gttgtttctt gacagtcatg actaatccag tagctaatca gactttcaat actggctaga
     3481 taaacctcaa gcgcgtagtg ataagggatc tgatagtgct tggtgatgat ttcttgaaag
     3541 ccatcaatag tggtcaaaaa ttgataaata aaatccttga gtatttgtga aaaattcaaa
     3601 taactggagt tagccatagc agcaataaag ggaagattat caatgatata agcgagggct
     3661 tcctttagaa cgagtctagt atctgtaaaa atatgagggt catttaggag ctggtataaa
     3721 tcgtctaagg tgtcatttat gagatgagtc atcatatcat gtttatccct gtaatgcaga
     3781 taaaaggtgc ctctattgac accagctttt ttggttaagt cagaaacggt aatggtctca
     3841 aagctctttt ctgtcaaaag actgacaagt gcctgcttca aataggcctt ggttggtgtg
     3901 tgtcttgttg tcatcgactc atctccttaa gtcaacaaat gctgcttatc tgttcttgtt
     3961 aaagtcttga ggacattata taataaggct agtataaaat caacaaggtg ttgatataaa
     4021 ggaggtgaca tgatcagtgt cctatattga aatgaggtcc tcttcaaaga cctaccagat
     4081 tggagaaaca actgttaagg ctaatgatga ggtatccttt gagattgaaa gaggggagct
     4141 tgtgatcatt ttaggagcct ctggtgcagg caagtccaca gtgcttaata ttttaggcgg
     4201 catggatagc aatgaccaag gtcaggtcat aatagacggc aaggacatct cgacctatag
     4261 taaaaaggca ttgaccagct accgtcgtta cgaggttggc tttgtttttc aattttacaa
     4321 tctggtgcca aatctgacag caaaggaaaa tgttgagctg gcggctgata ttgtggcaga
     4381 tgcacttgat ccgactactg tcttaaatga ggtggggcta ggaggacgtt tggagcattt
     4441 cccagcacag ctatcaggag gtgagcagca aagggtgtct attgctcgtg ccttggctaa
     4501 aaatcctaag ttgttgcttt gtgatgagcc aacaggggct ttagattatc aaaccggcaa
     4561 gcaaatttta agattgcttc aagatatggc gcacgacaag ggcaggacag ttattgtggt
     4621 gacgcataat actgctctag cgcctattgc tgatcgggtc atttatatgc atgacggtcg
     4681 tgtgaccaag acagtgctta ataagcagcc gcttgatatt gataggataa cgtattgaga
     4741 ggtgcctaga tgaaacaaaa aaccttatgg aaggatagtt ttcgagcaat aaaagctagt
     4801 aaggggcgtt ttttgtcctt gctattttta atggctctag gctcctttgc cttggttggc
     4861 ttaaaggtgg ctggtcccaa tatggaaaaa actgctagtc actatctaga ggagcatcag
     4921 gttatggacc ttagtatcct aacctcgcat ggcttttctg atagagataa gcaagaatta
     4981 gcctctctta aaaatgcaag actagagtat gcgagctttg ttgatggtgc ttttgatcac
     5041 cagaggaagg ctattaggct ttattctatg ccacaaagcc tatctcaggc cagcttggtc
     5101 aagggagatt accctagcaa ggctagcgac attttgctat ctgaagcttt atcaagccgc
     5161 tatcggcttg ggcaaataat cacgataagc ctaaaaacaa agggattgct aaagcataga
     5221 tcctatcgtg ttgtcggctt tgctcattct ccagaaatat ggtccaaaac aaacttaggt
     5281 gtttcctcag caggggatgg taatctctat gcctatgcct accttcaccc tagtgccttt
     5341 cagcaagggc acaatctctt acgcattcgg tatgatgatt taagagggtt gaatgccttt
     5401 tcaactcaat acaatgaacg attgctacaa caccaagcag agcttgatca gatcttgcag
     5461 gacaatggtc aagagcgtta tgaagaaatg ctcaatgacc ttaatcgcag cttgaaagat
     5521 agtaaagtta agctcgaaga gcaaaggact gttcttaagg caagtgaaga ccagctggct
     5581 ttgctaagtg gtcatgcctt agagcaagcg cagactcagc taaagcaagg gcaggaagag
     5641 ttagctaaaa aagaagcaag cttgctagag ttagctgaaa agcaaagggc agcgatgatc
     5701 aagccaacct atactagcta tagtcgctca acgctgccag gtggtgaggg ttatcaaacc
     5761 tatgccacct caacacagtc catatcgcat gttggaaata tctttcctgt tgttttgtat
     5821 ttggttgcgg ccttagttac ttttacaaca atggctcgct atgttgacga agaacgaacg
     5881 aactcaggct tactaaaggc aataggctat tctgattggg atattaccaa aaaatttctg
     5941 ctatatggtg ccttagctgc cttgttgggc actggattag gagttttagg agggacttat
     6001 tttttatctc ggctcatctc agctatccta acagatgcat tgactatcgg ctctactcag
     6061 ctttattttt attggagcta tagtgtggtt gcagtgcttt tagccttgtt atctgctgtt
     6121 ttgacagctt atatggtggt gagacgtgag ctttttctca gaccctcaca actgttgctg
     6181 cctaagcctc ctagtagcgg ggcaaggatt tggctggagc atgtctcctt tatctggcgg
     6241 cgtttatcct ttacctataa ggttactttt cgaaatatct ttcgatataa gcaaagaatg
     6301 ctgatgacag taattggagt agcaggttct gttgcgctct tattttccgg cttgggcatt
     6361 caatcctcac ttgctaatag cctaagctat caatttggca agctgacagc ctatgacatg
     6421 ctcgtggtag aagctccaac agcagaagct catgataggc aggagctggc acaatatttg
     6481 aaggcagatc agattgctag taagaaagag atttattacg ctaacttatc actaaagata
     6541 aaagacttag acaacaagca aacagtgtcg ttgatttcta gcgatcagag cactctatct
     6601 ccctatttta gcttgattgg tgctgctgac cgaaaaaagc tagaccttcc aagtactgga
     6661 gtgcttatct caaaaaagct tgctgactat tatcaggctc atgcaggaga tcagcttgag
     6721 cttgaagcta gtaacggtaa acgctatcag ttaagagtga gtcaggttat tgacatgact
     6781 gttggtcatt acttgttcat gtctaaatct tattatcagc aggtatttcg ggatatggag
     6841 gcttcaccat cctatttggt aacaacagca aaggctagtc catctgctgt aaaggacgta
     6901 gctagtcagc tcttagcaat gcctgcggtt caggctgtgt cacaacacag tagtattgtt
     6961 gctactgtga cagggattgt ggcgtctttg gatcaggtta tgacgctttt agtacttcta
     7021 tcagttctac tagccttggt cattttgtat catttgacca atatcaatat tgctgagagg
     7081 gttagggaat tatcaacgat aagagtcttg ggcttttatg acaaggaggt taccttatac
     7141 atttaccggg aaaccatgct tttgtctgct gttggtattt tgatcggtct ctggggtggc
     7201 agctatttgc acgcctatat catgaaggtg attgctaatg attctatgag ctttggtagg
     7261 acagttgatg cttatgttta cctagtacct gttggggcta ttgtgctttt gttgattgtg
     7321 cttggctata tggttagcta ccggctaaga aagattgata tgctagaggc tctaaagtct
     7381 gttgattagg gtaaaatagt acttgaaaat cgcttaataa tatgctagta ttaaaatact
     7441 ataatttaat agaaggatac ttttatggaa gcgatgatag ctgcctattt ggctgatcat
     7501 agagaaaaga taccacttgg tcaggttgtt gattgcttta aggggaaggc tgtttctcgt
     7561 aaggctgagg ctggtgaatt tggtttgatt aatctgtctg atatgggaca gctaggaatt
     7621 gactatcatc aggttagagc ctttcatatg gatagacgac aactattgcg ctatatctta
     7681 gaggatggag atgtcttgat tgcctcaaag gggactgttc agaaggtttg tgtttttcat
     7741 aagcaagaaa gggaaatggt agcgtcctct aatatcacag tgctgcgtcc tcagagggtt
     7801 ttgcgaggct attatattaa gttctttttg gagtctgcta ttggtcaagc cttgttaaag
     7861 gcggcggatc atggaaagga cgtgattaac ctatcgacca aggctttact tgatatccct
     7921 gtaccagtga ttcctttggt taagcaggat tatttgatta atcaatattt gcgaggcctg
     7981 catgactatc aacggaaagt aaacagagct gagcaggagt ggcagtttat tcaaaatgaa
     8041 attcaaaaag gcttgggcta gaggtaaaat gtgagcttaa ttgaacgaac aataaaaatg
     8101 ctattagcaa cgatggctgc aatctttctt gcctctcagc tacagctgtc ttatgccata
     8161 tcagcgggaa ttattgccct gttaggtgtg ctagacacta gaaaatctag cttaattgtt
     8221 gctagaaagc gtctgctgtc ttttttctta gcctttgctg tggcggttag tctatttgcc
     8281 ttatttggct ttggtctgct ttccattggc ttgtatctag cgctaaccat tcctttgctt
     8341 tatcagctga aaatagaggc aggtcttgtt cctatcactg tcttggtgac tcacctgatg
     8401 tctgagcagc gtattgattt gtcaattctt tttaatgagc tgttgctgtt tttgattggg
     8461 acgggtcttg cccttcttgt taacgggtat atggggtctc aggagcatcg cctacgcttg
     8521 taccaccaaa agatagaaga tagcttaaag gctatcttgt accgttttga atcctttttg
     8581 ttagaaggcc aaggacaaaa cgagggacag atgattaagg aattagagct tagcttagat
     8641 gaggcgctaa agctggttta tcgcgaaagg cacaataccc tcttttatca taccaattat
     8701 caggtgcatt attttgagat gagacgtcat caaaatagat tgttggcgca aatggcctta
     8761 aatgtcactc agctaacatc tcaaagcaga gaaagtctcc tgctctccca tctttttcat
     8821 gagacagctc gtcagctgag tgagaagaat tctgctttga cattgattga tgatattgag
     8881 caattgcttg aggtctttag gcaaagagag ctgcctcaga ctagagagga atttgaaaga
     8941 cgggcgattc tgtttcagct gttgcaggat ttggagcgct ttattctact gaaggtagaa
     9001 ttttatcgtg attacaagga agagcaggca tagtagctgc ttgctgctgt gattaagagt
     9061 ctggaaaaat cattttctag gcttttttgc tataatcccg actttatcac ttgttttagt
     9121 ccacacctta ctcaacc
//
LOCUS       DARYLD010000076         9016 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYLD010000076 DARYLD010000000
VERSION     DARYLD010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9016
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TU651_001769"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TU651_001769"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL0897735.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TU651_001770"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TU651_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL0897736.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TU651_001771"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TU651_001771"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL0897737.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TU651_001772"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TU651_001772"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL0897738.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TU651_001773"
     CDS             complement(6925..7623)
                     /locus_tag="TU651_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL0897739.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..8227)
                     /locus_tag="TU651_001774"
                     /pseudo
     CDS             complement(8009..8227)
                     /locus_tag="TU651_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678102.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8216..8491)
                     /locus_tag="TU651_001775"
                     /pseudo
     CDS             complement(8216..8491)
                     /locus_tag="TU651_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006740630.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
     gene            complement(8932..9016)
                     /locus_tag="TU651_001776"
                     /pseudo
     CDS             complement(8932..9016)
                     /locus_tag="TU651_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679400.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; incomplete; partial in the middle
                     of a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
BASE COUNT         2655 a         2141 c         1773 g         2447 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatt
//
LOCUS       DARYLD010000077         7716 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYLD010000077 DARYLD010000000
VERSION     DARYLD010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7716
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..405
                     /locus_tag="TU651_001777"
     CDS             <1..405
                     /locus_tag="TU651_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL0897740.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TU651_001778"
     CDS             414..1085
                     /locus_tag="TU651_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897741.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TU651_001779"
     CDS             1102..3375
                     /locus_tag="TU651_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897742.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
     gene            3849..5870
                     /locus_tag="TU651_001780"
     CDS             3849..5870
                     /locus_tag="TU651_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0897743.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAEAKARTAEEEAKQATADKEKAETEAKKAKE
                     EAKTAKEAAHQEQEKAKQLEQANQQANQRANLAEKSKKDLETQKEKLEQEIKEATEAK
                     NKAEQKLKDLQDSASQGSELSKQLLKEKEELTTKLQELQKQAEEKTTEIEKLKQELEA
                     NKQNSGQLGQQEQKLQEQLNKVQKELKQKEMELKQAQEQLKQEQKPHEGGGDSDASKA
                     RITELEKQVQTLTKEKADLSSTLESTKAQLSETQARLSEAQKQLTAAQEKLTTLEAEK
                     TALQHQVETISKQLSETRDLSEKEKAALQEQINKLKAEIEQKTKEIEALKQGMQSHQG
                     QEKPKDPKTPETPKDPKTPEKNDQPQAPEKRSVPWTALTPAKPIDTTKAPKSSAPSPQ
                     TGAATPKKQLPATGDTATPSFFTAAAMAVLASVGVLNLSPRRKKNQNNR"
     gene            6287..7129
                     /locus_tag="TU651_001781"
     CDS             6287..7129
                     /locus_tag="TU651_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL0897744.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(7232..>7716)
                     /locus_tag="TU651_001782"
     CDS             complement(7232..>7716)
                     /locus_tag="TU651_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL0897745.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         2552 a         1595 c         1541 g         2028 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg tttattaaaa
     3721 aaaaaaaaaa cgaaactacg gagagaaaga tgagctttgt cgtttctcac ttccaaccgc
     3781 catgttaaaa tcttctctga gaaagaatgt tataaaaaat aatcattcta tcaccaaagg
     3841 agagaaaaat gataactaaa aaacagagaa aactaaaaag acacacaaca atcagacgcc
     3901 tgtgtcatca agccctagca gctaccctca tcacaggaag cctgatggga acaggactac
     3961 ttggaaataa agtcgtgtat ggggatatga aaagcgatgc caaaaaggta ttagcaacat
     4021 tgcaaaaagg taatcataaa caagagttaa aaaaagttct tagaactatt ggtgatgata
     4081 gtttgctatt attatggtta cttgtatcgg gtgattccaa tttagatgaa agtaataaaa
     4141 gttttgatta tttatcaatt tggaatactg gatctagagt tggtaaagtg atatctccta
     4201 ctgaatactt taaacaagaa tcaaaaaaca ctgaaaatag gcaagctgtt tatagtgaat
     4261 ttaaacaacg cgtagaagaa cgatctaaaa aagccaagga agccactgaa gcactaaacc
     4321 aaaaagctca attggaggct acagttaaaa atataaacga agaacttgaa aaaactagag
     4381 aaggttttaa agttgtgagt gaaaactcaa acaaattaga aaaacaatta atggctgaga
     4441 aaataaaaac acgtacagct gaagaaactg ccaaacaagc taaaaccgat aaagaaaaag
     4501 cagaggctga agctaaaaaa gcgaaagagg aagctaagac tgcggaagga aaagttaaac
     4561 aagcagaaac tgagaaaagg aatgcggaag ctaaggctag aaccgctgaa gaagaagcta
     4621 aacaagctac ggctgataaa gaaaaggcag agactgaagc taaaaaagcg aaagaagaag
     4681 ctaagaccgc taaagaagct gctcatcaag aacaagaaaa agctaaacaa ttagaacaag
     4741 ctaatcaaca ggctaaccaa agagctaatc tggcagaaaa atctaaaaaa gatttagaaa
     4801 ctcaaaaaga aaaacttgaa caagagatta aagaagctac agaagctaaa aacaaagccg
     4861 agcaaaaatt aaaagaccta caagattcag ctagtcaagg cagtgaattg tctaaacagc
     4921 tgttaaaaga aaaagaagaa ttaacaacaa aacttcaaga gcttcaaaaa caagctgagg
     4981 aaaaaacaac tgaaattgaa aagctaaaac aagagcttga agctaataaa caaaacagtg
     5041 gtcagctagg tcaacaggaa caaaagcttc aagagcaatt gaataaggtt caaaaagagc
     5101 tgaaacaaaa ggaaatggag ttaaaacaag ctcaagaaca gctgaaacaa gaacaaaaac
     5161 ctcacgaagg tggcggagat tctgacgctt ccaaagcaag aatcactgag ctagaaaaac
     5221 aagttcaaac actaaccaag gaaaaggcag atctgtcatc aacccttgag tcaacaaaag
     5281 ctcaattgtc agagactcaa gcaagactat cagaagctca aaaacaattg actgctgctc
     5341 aagaaaagtt aacaacactt gaagccgaga aaacagcgct tcaacatcaa gttgagacca
     5401 tttcaaaaca gctatcagaa acacgtgacc ttagcgaaaa ggaaaaagca gcactccaag
     5461 agcaaatcaa taagctaaag gctgagattg agcaaaagac caaggaaatt gaagccttaa
     5521 agcaaggcat gcaatcacat caaggtcaag aaaaaccaaa ggatccaaaa actccggaaa
     5581 caccaaagga tccaaagact cctgagaaaa acgatcagcc acaagcgcct gaaaaacgta
     5641 gtgtcccttg gactgctctt acaccagcta agccaattga cactaccaaa gctcctaaga
     5701 gctcagcacc aagcccacag actggggcag caacacctaa aaaacaatta ccagcaactg
     5761 gtgatacagc gacacctagc ttctttaccg ctgctgctat ggcagtattg gctagcgtcg
     5821 gtgtcctaaa tctctcacct agacgcaaaa agaatcaaaa caaccgttaa tgtagagact
     5881 ctcatatctg gattgaataa cagcaaaccc gacatgagca aaaacaaatg tctaaccaaa
     5941 aatcactgac attagtactt taaccaaagc ctttgagtca agctaaacag gctgtcctgc
     6001 ctattggctt gactcgtttt gtgattgtga aacacaccaa ggtcaaacct accttgtcct
     6061 ccattttaaa cctactcttt tctcccatac ccactttagc ttacgcaaga aggtgcctaa
     6121 tcatcacttt tggtagcttc gatgctctat ataaatggat caacaaagat aaatcataca
     6181 aaactgcgag ttgttcctat agtcacgata gctcttacag atatgaaaag taaatacagc
     6241 tattaaaaat atggtacaat aggggtacga tttttaggag gcatgtatgg tttcagttct
     6301 ttcacgagtg attaagggaa taattattgc gcttggcttt attttaccgg gagtatctgg
     6361 aggagtatta gccgctatcc ttgggatcta tgagcgtatc attgcctttt tagctcatat
     6421 acgtgagcat tttgttgaga atgttctctt tttcctgcct gttggggttg gtggtatttt
     6481 agggattgcc ctcttttctt accctgttga ctatctgctc aagcactatc aggtaccagt
     6541 cttatggggc ttcgctgggg ccatcatagg aaccgtacct agcctgataa agacttcgac
     6601 aaaaacatct cagcgtgacc aagttgattg gctctggcta gtattaacct ttgtcctatc
     6661 aggactggga ctttatttct taaatgatct cgttgggaca atacctgcaa gctttaccgc
     6721 ctttgtccta gctggtgcct tgattgcttt aggtattttg gtacctggtc ttagcccgtc
     6781 taatctttta ttaattttag gactttactc acccatgctg attggcttta aatcacttga
     6841 tttggtagga acctttttac ccattgctat tggtggctta ttaaccatgc tagctttttc
     6901 caagattatg gattttgctc tcaagcacta ccattcacgc gtttaccact ttattatcgg
     6961 tatcgtccta tccagcaccc tgcttatttt aattccaaat agcagtaata aggaagctat
     7021 ctcttacgcc ggtgcaggtc ttggcacctg gctaatggct ctgctattat ttggccttgg
     7081 tgtctggctt ggtctatgga tgagccagct tgaggagaaa tacaaataac actcgataca
     7141 ccagcaagta cctctaacag cagcattaag atcaaaaaaa cgaatgacta gctctcagcc
     7201 ttatcaccag ctgtgactag cattcgtttt tttatatgtc atcatgctgt cttgcctctg
     7261 tcacgatttc tataaaacgg ttcgtcaatt gagcagttat accccagata ggcttttcta
     7321 aatgctcata gagtaatacc tgatcttgca tgtacctcaa cctgtactgc tctccattag
     7381 ggatacgatc caacggaaag tctgacgaga ttatcgattg catttgtaaa ggataagcaa
     7441 caggagcttg cgccatgagc tcctccaaag gcaccgtaaa caagctatca acctcttcat
     7501 tgaccctaag ccttctccaa tcatcaatag ccagttccgc aacaaagcaa tgaatgctac
     7561 gagtcggctg aactaaatag tcaatctccc cccaaacatg aacctgctca ggctctatat
     7621 tgagctcctc taccgtctca cgaatagccg cctgctgata agtctcaccc tcctccacgc
     7681 gcccactagg aaaagaaacc tcccctggct tgaatg
//
LOCUS       DARYLD010000078         7569 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYLD010000078 DARYLD010000000
VERSION     DARYLD010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7569
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            91..1149
                     /locus_tag="TU651_001783"
     CDS             91..1149
                     /locus_tag="TU651_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL0897746.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            1161..2084
                     /locus_tag="TU651_001784"
     CDS             1161..2084
                     /locus_tag="TU651_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL0897747.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            2519..3232
                     /locus_tag="TU651_001785"
     CDS             2519..3232
                     /locus_tag="TU651_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL0897748.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            3229..4140
                     /gene="pfkB"
                     /locus_tag="TU651_001786"
     CDS             3229..4140
                     /gene="pfkB"
                     /locus_tag="TU651_001786"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL0897749.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            4137..6083
                     /locus_tag="TU651_001787"
     CDS             4137..6083
                     /locus_tag="TU651_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL0897750.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            6661..7260
                     /locus_tag="TU651_001788"
     CDS             6661..7260
                     /locus_tag="TU651_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0897751.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
BASE COUNT         2120 a         1382 c         1773 g         2294 t
ORIGIN      
        1 aaaattaaaa tagctgtgac aaaatgctct ttttatgtta gaatactttc gtgatgtttt
       61 tcacactata atattaagag aggtcatgaa atgacaacaa caaataaaga gacctttagc
      121 tcgtttatga ataaggtctt agctggtaca gcaattgcga ttgtagttgc acttattccg
      181 aatgctattt tagcgacgtt tttaaagccg cttttgccaa atactgtagc agctgaattt
      241 ttacatatcg tccaggtttt ccaattcttt acgccagtta tggctggttt tttgattgga
      301 cagcagttca aatttaaccc aatgcagcag ctggctgtcg gcggggcagc ttatatcggt
      361 tctggagctt gggcttatac agaggttatc caaaaaggtg ttgccactgg gaccttccag
      421 ctaaagggca ttggtgatct gattaatatg atgatcacag ctgcgcttgc cgttttagca
      481 gtgaagtggt ttggtgataa atttgggtct ctaaccatta ttttgttgcc aattattatt
      541 ggaacaggtg tgggttacat tggctggaag ctgcttcctt acgtttctta tgtgacgacc
      601 ctgattggcc aaggcattaa ttcatttaca acgcttcagc caattctgat gtctattttg
      661 attgccattg cctttgctct tttgattgtg agtccgatct caacggttgc gattggttta
      721 gctatcggct taaatggtat ggcagctggt gcggcctcaa tgggtattgc ttcaacaacc
      781 gctgttcttg tgtgggcaac gttaaaggtt aacaaatcag gtgttccaat tgccattgcc
      841 cttggcgcta tgaaaatgat gatgccaaac ttcttaaaat acccagttat ggctattcca
      901 atgatgatga cagctattgt tagctcttta accgttccaa tgtttaatct gattggaaca
      961 ccagcctcat ctggctttgg tcttgttggt gcagttggtc ctattgcttc acttgccggt
     1021 ggcagcaata ttgtgatcat tatcattgct tggttggtca ttccatttgg agttgctttt
     1081 gtggcacata agctttgtaa ggatatttta aagctttata aagaagatat ttttgtattt
     1141 gaaggataag aggaaaaagc atgttagttt atattgcagg ctcaggagct atgggctgtc
     1201 gatttggtta ccaaatttca aaaacaaaca atgacgttat tttactggat aattgggaag
     1261 cacatcttca agcgatcaaa gagaatggct tgaagatttc aggcgatgta gaggaaaccg
     1321 taaagcttcc tatcatgaag ccgacagagg ctactaagga agctgacctt atcattttgt
     1381 ttaccaaagc catgcagctg ccacaaatgc tgactgatat taaaggtatt attggccctg
     1441 aaaccaaggt actttgccta ttaaatggtc ttggacacga agatgtgatt cgtcactata
     1501 ttccagagca taatatttta atgggtgtta ccgtttggac agcgggtctt gagggacctg
     1561 gtcaggtaca cttacaagga gttggtgcgc ttaatctaca aagcatggat ccagcaaacc
     1621 aagaggcagg acatcagatt gctgacttgc taaatgacgc tcaattgaat gcaacttatg
     1681 atgataatgt tgttccaaat atttggagaa aagcctgtgt caatggtaca atgaactcaa
     1741 cctgtgccct acttgattgc acgattggtg agttatttgc cagcgaagat ggtttaaaca
     1801 tggttaaaga aatcattcat gagtttgtta ttgttggtcg tgctgagggg gtggagctta
     1861 atgaagagga aatcacagcc tatgtgatgg aaacctcagt gaaggctgct catcactacc
     1921 catcaatgca tcaggatctt gttcaaaatc accgcttgac tgaaattgac tttatcaacg
     1981 gtgcggtaaa taccaagggt gaaaagcttg gtatcgatac cccttattgc cgcttgatta
     2041 cacagctagt ccatgccaaa gagaatattt tgaagatcaa ataggtttag acataaggag
     2101 tctgggataa aacaatttct cagtacaata aaacgagagg ctcacaatag gtgactctct
     2161 cgttttgtct tgttggctga aaagactttg tcctagactc tcattatgaa gcaacgacag
     2221 taaatccgtt gctttttgat ttgtaagaga ctattgtgtt tcagactttt gcaacaggtg
     2281 agcgcttttt gggctctagt taataaaaaa gtcgttaatc attagtctac aggtattgac
     2341 ggggacaatg actgatcaat tggcagttat tgttaaggca atagaggtct aagattgaat
     2401 ttgaatgttt ttgaaagata gtgcttgact ttggaataaa gtgtagtata atagagctgt
     2461 aaacgatttc agacaaaggg gtggttttat cttaaaatca aaacgaaaac agctcattat
     2521 ggcaaaaatc acagctgaga attacgttgc gctagaggat ttaatgcagc tgttaagctc
     2581 gtcagaatca actgttcgta gagatttaga tgagctggag cgtgagggca agcttcatcg
     2641 agtgcatgga ggtgccgagc tttttcattc cttacaagag gaattatcta atcaggaaaa
     2701 atctgtcaaa aacagtcaaa taaaagaaat catcgctcaa aaggcagcag agctggtttt
     2761 tgataatgat gtcatcttta ttgatgctgg gacaacaacc gaatttctcc ttcctttttt
     2821 gcaattaaaa aaagtaacag tagtgactaa ttctattcat catgcgacta gactggttga
     2881 tatggcgatc aagaccatta ttattggtgg ctatgtcaag cagacaacag acgcaagcat
     2941 cggtcatgtt gccttggagc aaattaggca aatgaatttt gataaggctt ttcttggtat
     3001 caatggtatc gatgaggcat ttttaaccac tccggatatg gaggaggctg ttattaaaaa
     3061 agctgtcatt gccaatgcta aaatcaccta tgtattagct gatgcaacaa agcttggtca
     3121 tgtttccttt gtcaaggttg ctccaattga tagggttgaa atcattacag agaaatcttc
     3181 gacagtaatg ctgaagaaaa tcaaggaaaa agcgaaggta attgcactat gatttacaca
     3241 gtaaccttaa atccttctat agactttatt gtcagaatag accaattaga tattggagcg
     3301 gttaaccgca tggtcagtga cgatacattt gcaggaggaa aggggattaa tgttagtcgc
     3361 attctacagc gattaggcat tgataataca gcgactggct ttttaggcgg cttcactggg
     3421 cgttttatta aggaaagtct agctgctgag agcatcaata ctgactttgt aacggttgat
     3481 caggatacgc ggatcaatgt taagatcaaa tcagcagagg agacagagat taatggcctt
     3541 ggaccagtga tttcaaagca gcaattggat catttaaagg ctatattggc aaatgtgtca
     3601 gcagaggaca ttgttgtttt tgcaggctca gcgccttcaa gtctaggcaa tgatgtctat
     3661 aaggacttga tcccattggt cagacaagct ggggcacagg tggtctgtga ttttgaagga
     3721 cagaccttgc tagatgcatt ggcgtatcac ccattgctcg taaagcctaa taaccatgag
     3781 ctagaagcta tttttaacgt cagcttaaat gggctagatg acgttgaaac atatgctcgt
     3841 aaggtccttg acatgggagc gcagcatgtt atcgtttcga tggctggtga tggtgccttg
     3901 ctggtcactc aggaagcaac ttattttgct aagcctatta aagggcaggt gaagaattct
     3961 gttggagctg gtgattcgat ggtggcaggc tttacaggtg cctttgtcaa aagtcatagt
     4021 ccgctagagg ctctaaaatg gggagtggcc tgcggaacag caactgcttt ttcagatgat
     4081 ttagcagcaa ttgatgatat taaaaaaaca tataatgagg ttgaggtaga ggttcgatga
     4141 aaatacagga tttattaaga aaagacatca tgattcttga tttgcaggct gtttcaaaag
     4201 aggctgcaat tgatgaaatg attacagaac tagtagagca tgggattgta catgactttg
     4261 atgtgtttaa aaagagtatc ttagctcgcg aggagcaaac ctcaacaggt cttggcgatg
     4321 gcattgctat gccgcattca aaaaatgttg ttgttgacca gccagcagtg ctctttgcaa
     4381 aatctaacaa gggcgttgat tacaaatcct tagacggtca gccaactgat ctgttcttta
     4441 tgattgcagc acctcaaggg gcaaatgata ctcacttagc ggccttagcc gaattatccc
     4501 aatacctatt aaaggatggc tttgcagatc aactgcgaaa ggcaacaagt ccagacgaag
     4561 tgattgctgt ctttgatgcg gcttctgatc agaaagaggt agcttttgtt cctacaaatg
     4621 ctcaggagtt tatcgttgct gtgacagctt gtacgacagg tattgcacat acttatatgg
     4681 cagaagaggc cttgaaaaag caggctgcac agatgggtgt cggcatcaag gttgaaacca
     4741 acggtgcttc aggggttggc aatcgcctga cagctgatga catcaagcag gccaagggag
     4801 tgattatcgc tgctgataag gcggttgaga tggatcgctt tgatggtaag caattgattg
     4861 ctcgtcctgt agcagatggt attaagaaaa gcgaggaatt gatttcactg attttaaaca
     4921 atgctggtag tgtttatcat gccaagaatg gcgctgctga acaagcaaaa gcagctcaaa
     4981 agacaagcct aggcggagcc ttctacaagc acctgatgag tggtgtatca caaatgctgc
     5041 catttgtaat tggtggtgga atcctaattg ctcttgcctt cttgcttgac aacatgcttg
     5101 gggtaccaaa ggatcagctg tctaatttgg gatcctacca tgaaatagca gctatcttta
     5161 aacatattgg tggtgcggcc ttttcattca tgttgccagt gctagcaggc tacattgctt
     5221 attctatcgc tgaaaagcca ggtcttgtgg caggctttgt ggcaggtgcc attgcttcta
     5281 gcggtcttgc ttttggaaag gttccatttg ctgctggcgg tgaggctagc ctatcattag
     5341 cgggagtacc gtctggattt cttggtgcgc ttgtaggtgg cttccttgca gggggagtaa
     5401 ttcttgctct tcgtcaagtg cttgcagggc ttccgcgttc gcttgaaggg gtcaagtcaa
     5461 tccttcttta cccattactt ggtgttcttg tgacaggtct tttgatgctg ctgatcaata
     5521 ttcctatggc agctatcaat acagcattga accacttctt agaaagtctg tcaggtagct
     5581 ctgcagttct tatgggactt cttgttggcg gcatgatggc tgttgatatg ggtggtccag
     5641 tgaataaggc agcctatgtc tttggtacag gaacacttgc tgcaaccgtt gcaagcggtg
     5701 ggtcagttgt tatggctgct gtcatggcag gtggtatggt gcctcctcta gctgtttttg
     5761 tggcaacact cttatttaaa gacaaattta ccaaggaaga gcgtgaatct ggcttgacca
     5821 acattattat gggactttcc ttcattacag aaggagccat tccgtttggt gcagcagacc
     5881 cagcacgcgc tatcccaagc tttatcgctg gctctgccct aacaggtgct cttgttggtc
     5941 tagcaggtgt caaattaatc gcaccacatg gcggtatctt cgttatcgct ttgacaagca
     6001 atcctttctt atacctattg tttgtcgcta ttggagcagt ggtttctggt attctctttg
     6061 gcgcacttcg taaaaaagct tagttactgg ctataaagcc acaagtacta gggaaagctt
     6121 ctgaattaga cctagtctta ataaaacatc agacgcatga catcagcctg tttttacatg
     6181 atgtcgtgcg ttttgtttgt tgctagtagt gatgactggc gaaaagctaa tatttagaga
     6241 gaatcaatct gatctagaat agctaagcag tgacccaata gccctgctaa actaagccac
     6301 accaaacgtg cgaaacagtt attttcgaat tatagtatca attaaagtag atactatcaa
     6361 cgtttttcct atagtaacat ctatcaaaaa taagatatat tcttgaaata gctaaacatt
     6421 gaaatcattt gattgtagat attccattta ttttttgtat cgctcccttt gcaggagcgt
     6481 ggattgaaat acagcaaagt cttcttttct tgttaaaaac tttttatgcg cctgttgtgg
     6541 ctgctaggtc tttttagaag tcataaggcc tgtttttgag gtgagcatgt ggtctggcta
     6601 cattttgctt ttaatttttg ctatactagg tttaaaagca aggaagtgag gatatttctg
     6661 ttgaagagga ggaaagctag aagaagccac agggaagcta gctcttggct ggctgctggt
     6721 attgttttag gcagcatgtt gcttagcctt tggaccttag cgtcagctaa ggatcacctt
     6781 aagcctcatg ccaatagctc aaccatgcta tttgtgagca agattagtca ttccgctcag
     6841 gcagttgcgc agcgaaacaa gctctatgcc tcagtcatga tggcacaggc tattttggag
     6901 tcagcaaatg gtcaatctaa gctaagtcaa gagccctatt ataatttttt tggtatcaaa
     6961 ggaagctata aaggaaaatc agttatttta cctaccttgg aagatgatgg ccaaggcaac
     7021 ctttatctaa ttgacgcttc ttttcggtcc tatggcagct taacagcctg ctttgaggat
     7081 tatgctaggg ttttgagtga cccgctttat cgccctactc accgaggtat tcatacaagt
     7141 tatcagcagg ccaccgctag tttaacaggc acatatgcca cagatactag ctatggcgaa
     7201 aagctcaatc gtattatagg ggattatcag ctgacttatt ttgacgctcc catacggtag
     7261 ctacctccag catgactgat ctaacgagat taacctcatc agaacagcaa aataattttc
     7321 taaaatagtt agaaaagatc aaacagccct ttacgaacgt ttaagacgag atggtgacat
     7381 gcaaggagaa agcaattcta caaatgatgt gagaaaatac tatgtgtaag gctgggtaga
     7441 tgattaaacg gtctggtttg gcttattgat ggattaaatg gatagttaaa ctacaaatag
     7501 acaaggtgta tttttacctg taagtagtgg ctaacagtga gatagcagaa atgctatctt
     7561 cttttgatt
//
LOCUS       DARYLD010000079         7497 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYLD010000079 DARYLD010000000
VERSION     DARYLD010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7497
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            438..977
                     /locus_tag="TU651_001789"
     CDS             438..977
                     /locus_tag="TU651_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897752.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            974..2089
                     /locus_tag="TU651_001790"
     CDS             974..2089
                     /locus_tag="TU651_001790"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL0897753.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGRYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2079..3341
                     /locus_tag="TU651_001791"
     CDS             2079..3341
                     /locus_tag="TU651_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0897754.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3387..4406
                     /locus_tag="TU651_001792"
     CDS             3387..4406
                     /locus_tag="TU651_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL0897755.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4605..5315
                     /locus_tag="TU651_001793"
     CDS             4605..5315
                     /locus_tag="TU651_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897756.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5308..6660
                     /gene="vicK"
                     /locus_tag="TU651_001794"
     CDS             5308..6660
                     /gene="vicK"
                     /locus_tag="TU651_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL0897757.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6664..7473
                     /locus_tag="TU651_001795"
     CDS             6664..7473
                     /locus_tag="TU651_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL0897758.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2018 a         1599 c         1800 g         2080 t
ORIGIN      
        1 gtcctcggca cgatagtcct gaacccttgt ttcagcctac ttcttcactg tcctaagatc
       61 gcttttagga tggccttgcc aagtctaggc cttagttgga gtaccgtaac attcgcagca
      121 gcctttatca gctaatgtct tagaatgata ataggtcatg cgacttatct agcgcgtgaa
      181 tgaccttgaa gcttgccttg tgtgctttct tctgtctatt tcaagtagag ctgaatgact
      241 atcagttacc tgtaggcaga ggctgtagca gccttgattt attaaatgat attgaacatg
      301 atgtgatcag acaaaaaagg ttaggctaaa ggctcgcctt tttttgctaa ctaagccttg
      361 tttttgctgt tttttctttt cttgtgttca ggtattcagt ataataaagt taacttgttc
      421 gcaaaaggat ggttacaatg agacagctaa tcgcagctat ggttgagaaa aatcaggatt
      481 taccaagaaa catccttgtg gctgagatga gcttggaaaa agctgtgcag ccagatgatt
      541 atcgcgtaaa ggattatcga aatctgcggc agatcagatt gactacatca gggcttgtgc
      601 tagaggttcg attactaaaa gggctaccag ccaggtggct gaaaaaggac acaagtgcta
      661 agccttctaa agcagttaat agccgagcat tagctgagca tagccatgta ctgagcgtta
      721 atcaggcggc cttacagcaa tttctagcag aaacaggaga tcaaaatcct cttcatcaaa
      781 cagctcccta tatcttaccg ggagccctct tgatggaaga ggttagcagc tggcttactt
      841 tagattaccg taggctaagc ctgcgttttt atgccccagc ggttgtgaat gctcctattc
      901 acctagtgat gagagaaaaa gctatcagcc tctatcaggc aggagaatta gtcgcaaaag
      961 gagagcttca cgtatgattg atgtctacat tcaaagaggg cttagaacgc ctattggtct
     1021 agctggcaag caatttgcta gggtgcgtcc agaactgctt ggtgctcagc tgattaatgc
     1081 cttagtcaaa gcagataagc tggctattga tgaggtgatc tgcggtaatg ctgttgggac
     1141 aggcggtaat attggccggc tgatgactct gtattctgac ttgggagaga ccgtacctgc
     1201 cataaccgtt gacatgcaat gtgcctcggc tggtgcagct cttactatgg gctatgctaa
     1261 aatcaaggca ggtcttgcca ctagcttgtt agcaggaggg atcgaaagca gctctttgca
     1321 gcctcagcgt atctatgctg ctgctgatag ccgatcaggt gcttatcagg tagctcagtt
     1381 ttcaccagat accagtagcc agctggctat gatagcagga gcagagcggg tggctcaggc
     1441 ctaccaaatg accccctcac agctcaacca gtggaccctt actagccacc agcgagcaca
     1501 catagctagg cagaagcatt ggttagctga tattatatta gcaatgccag gaatgtctga
     1561 tcaaggcatt cgccctcgcc tgtcagaaaa ggtcttgagc aaggtgccgc cgatacttga
     1621 taaggctggc ctcatcagtg ctgctaatac ctgcttgacc catgacgcag cagcattttt
     1681 agtgctaagc aatcaaagat cagcctatca aatccttgat cttgttgagg ttgctggcaa
     1741 tcctaaaacc agtcctcaaa tggtggttga ggccagtcag gtcttattag ctagaaacgg
     1801 cctagccatg acggatatgg atgcgatcga gtggaatgaa gcttttgcag tgattgatct
     1861 gctttttgag cattattttg tggaggccct tgatcgctac aatatttttg gaggcgctct
     1921 tgcctacggt catccctttg gcgcgtcagc agccattatc attttgcatc taatgcaggc
     1981 tttggcctta aagcaaggaa ggtatggttt agcagccatt ccagcagctg gtggtcaagc
     2041 ctttgccctg ttattggaat atcataagga ctactcacat gctatctaga ctgctagctt
     2101 gggcaagcca agcaccacaa agacctgcta tcctaacaga ccaaaaaacc ctaacctatc
     2161 aggatcttgt agagcagatc ttggcttatc agcctcagga gtctatctcc tatccgaccc
     2221 tgattgtcaa aagggattgc ttccagcagc tgattgcttt ttgctatcat ttgcaacatg
     2281 gaaactaccc acttatctgt cacccaaatc taccagaaca agagcaaagg cgtctgtcta
     2341 gctgcgatcc tccatcagac aaggcggctt ttgcggtgct tagctctggc tctactggcc
     2401 gtcccaaggt tttttggcgc tcctgggctt cttggtctaa tttttttgag cagcaaaacc
     2461 agctgtttta tttctcggag caaacaaggc tatttagcca tggaagcttg agctttacag
     2521 gcaatttgaa cttagctctg gcgcagctct gggccggagg ctgtctggtc tttagtgatc
     2581 agcggtcctt taagggctgg tcctctgttt ggcgcaggca aaaggttact catttatatc
     2641 tcttaccgag tctgctacag cggctactgc cttacttttc tgctgatagc tattttgccc
     2701 cgtatttatt aacctcatct cagcacttgt caccagagct gattcgcagc tattaccaac
     2761 gctttccgcg gcttgagttg ttgatgtttt acggtgccag tgagctttcc tttatcagct
     2821 ggtgtcaggg ctttgaggct atggcaatag ctggctttgt agggcgtccc tttcctcagg
     2881 taaagctgga gctccgagag gggcacattt ttgttcagac tccctatgcc attgagggca
     2941 ttgagcagcc ctatagtgtc gatgatgtgg gggaaatgac agcagcaggc ttgattctaa
     3001 aggggcgaac caaggactgg gtgaatcagc aaggtgtcaa atgccatctt cctagccttg
     3061 ttcagctagt ccaccagtca ggagttgttc aagaagcagc agcgataaag ggtggcagca
     3121 gtgcagctga tgagcatgtg atcctgtgct tggtgttgaa aaagcaggga agccttaccg
     3181 ctgttaaggc ctatcttgag gcgcacctaa gcccagctca gaggcctaaa cggtatatac
     3241 tcttaaagga gctaccactt aatgacagtg gaaagcttga tagcagaagg cttagccagc
     3301 tcgcccacaa atcaactaaa gctgctcata acaccaaata aggaaaagtc acctgagccc
     3361 aaagcatcag ctcaatatgg tataatatgg tcaaaaaagg aggtcagttg atgaagcagg
     3421 atatgttagc acgttatcag gcactcaagc cttacgtaag agcaggtctt tcctcgacct
     3481 ctcagcagct attggcagct gcctcagcta ttgatgctcg cttaggctca ccgacctttt
     3541 tagccatttg gcagtgtgaa aaacagtgtc gatctcccaa ggaattacta gggcttgttc
     3601 tagatcttgt cggcatgcca atagagttat ccggaaggct agaggatacg caggctctgc
     3661 tgagtcgctt ttatcctgac ttgccaccgg atcattgctt ttgggtggag ctagcccaga
     3721 tggttagtct tgcttttccg gataaggagc tagcgcagca gagcgcgtta gctaagggtc
     3781 ttcatcagct tcgctatctc atttcgagcc agcaggcaca atatattcgc agccatttta
     3841 gatcagagga catgactgac gctcaggcac tggctatctt tctcaaggat aaaaaaggcc
     3901 cagctttttg gcgcagccag cctgactaca cgcttatgga atcggctcgt ctgcataaca
     3961 agctaaagct tgtcaatgga ttagcaagct ttcctgatca tgagatttcc cataatatta
     4021 aaattctgtt gcatttccat accgaattta tcctcgatag tcaggggtgt tttcttaatg
     4081 aaatagatgg tgaagtggtg accaacaagg gaatcattaa cggagcctcc ttcaattatg
     4141 gcacagcagg caagaggcat tgggagctag atgttgctcc tatcagccga catgacccga
     4201 cctttaggaa aaaatgctta gtaggccacc aagctcctaa gtggctgaag cgctcttggc
     4261 ttcagttatc gccactagat tttgactatt cttattttaa tgctaagggc ttttttagcc
     4321 tcaatagcaa aagctgcttt gccttggtta agcgacaggc acgtgccttt agatggcaga
     4381 tctggcgtag cagatttttt aagtaatgga tcagtagctg gcttgcttga tgaggtattt
     4441 agagagcgtt tttgtggcta gtatagtggt cattgtcaat ttctcctaaa ttttgatata
     4501 atcaaaagga cataataaaa tgatcggtct cgtctctaaa tccttatgga atagggatta
     4561 ggcagcgtag caattaatga agagaaatgt tctgaggtat aagcatgaag aaaatactga
     4621 ttgttgatga tgaaaagccg atttctgata tcattaaatt taatctgaca aaggaaggct
     4681 atgatacggt cacagcattt gatggcaaag aggccgttgc agtctttgaa gaggaaaagc
     4741 cagatttgat tattttggat ttgatgcttc ctgaattaga tggccttgag gtagccaagg
     4801 aaatccgcaa gaccagccat attcctatca tcatgctatc tgctaaggat agcgaatttg
     4861 ataaggtgat tggacttgaa ataggggccg atgattatgt gactaagccc ttttcaaatc
     4921 gtgagctgct ggcgcgtgtc aaggcacatt tgcgtcggac agagactatt gagacagcag
     4981 tagccgaaga aaatgcctcc tcaggctctc aggagctaac catcggcaat ctacagattt
     5041 taccagatgc ctttatcgct aaaaagcatg gtcaagaggt tgagctgacc catcgtgagt
     5101 ttgaattgct gcatcatctg gcaaaccata tcggacaggt catgacacgt gagcatttgc
     5161 ttgagaccgt atggggctac gattattttg gcgatgttcg aaccgttgac gttactatcc
     5221 gtcgcctgcg cgaaaaaata gaggatacac cgagtcgtcc agagtatatt ttgacaagac
     5281 gtggtgttgg gtactacatg aaggcttatg actaaggaca tcattggaaa cctttctgca
     5341 tttgagctag ccatactctt attgcttgtt tttgttgctt tttatttcat tcatttagcc
     5401 attcgtgatt atcgcaatgc tcggatcatt cgtctgatga gccataagat aagagatttg
     5461 atcaatggtc gctatactga tacgatcaat gaaaaggctg atattgaatt gatggagctg
     5521 tctgagcagc tcaacgacct atcagatgtt tttcgtctga cccatgaaaa ccttgcccaa
     5581 gagaaaaatc gtcttgctag tattttggct tatatgacag atggggtcct tgcgaccaat
     5641 cgttccggca agattatcat gattaatgag actgctcaaa agcagctcaa tttaaatcgt
     5701 gagcaggcgc tggaaaaaaa cattacagat ttattagaca gtgactcacc ttacacctac
     5761 cgagagctgg tctcaaaaac accgattgtg accttaaatc gtcgtaatga cacaggagag
     5821 tttgtttcgc tgcggctgcg ttttgcgctt aataggcgag agagcggctt tatttcaggt
     5881 ctagttgttg tgcttcatga cacgactgag caggaaaagg aggagcgtga gcgcagactc
     5941 tttgtctcaa atgttagcca tgagcttcgc acacctttga cctctgtcaa gtcataccta
     6001 gaggctctag atgagggcgc gctaaaggag gacatagccc caagctttat aaaggtctca
     6061 ctagacgaaa ccaatcgcat gatgcgcatg atttcagatt tgctcaatct atcaagaatt
     6121 gataatcatg tgacacagct gtctgttgaa atgaccaact ttacagcctt tatgacctct
     6181 atcttaaacc gctttgattt ggtgaaaaat cagcacacca gtactggaaa atcctatgaa
     6241 attgtcagag attaccctat cacctctatt tggctagaaa ttgataacga taaaatgacg
     6301 caggtcattg aaaatatttt aaacaatgcc atcaaatatt cacctgatgg tgggaaaatt
     6361 atcgtaaaca tgaaaacaac agatacccag ctaatcattt cgatttctga tgagggattg
     6421 ggcataccaa agaaggacct gcctttgatt tttgaccgtt tttaccgagt ggataaggct
     6481 agaagtcggg cgcagggggg ggccggctta gggctggcta ttgctaaaga aattattaag
     6541 cagcgccgcg gctttatctg ggctaagagt gactatggca aggggtcaac ctttaccatt
     6601 gtgttacctt acgaaaagga tgctgctatc tatgatgaat gggaggatga tattgattaa
     6661 ttgatgagtg aggttggctt taaatatagt attttagcat caggatcgac aggtaactgc
     6721 ttttacttgg aaacgcccaa gaagcgactg ttgattgatg caggactgac tggaaagaaa
     6781 atcaccagtc ttcttgctga gattgacaga aggcctgagg atttggatgc tatcttgatt
     6841 acccacgagc attccgacca tatcaagggt gttggaatca tggctcgaaa atataaccta
     6901 gatgtctatg ccaatgaaaa gacttggcag atgattgatg agcgtcatat gattggcaac
     6961 ctagacgtcg cacaaaagca tgtctttgaa agaggtaaga ccatgacctt tggagacatt
     7021 gacattgaga gctttggtgt tagtcatgac gctgtagacc cacagtttta ccgcattatg
     7081 aaggataaca agtcctttgt catgctgacg gatacaggat atgtgagcga ccgcttggct
     7141 gggatcattg aaaatgctga cggctacttg attgagtcaa atcacgatgt ggagatattg
     7201 cgagccggct cttatccttg gagcctcaag cagcgaatct tatctgacct agggcattta
     7261 tccaatgaag atggtgctgg cgctatgatt cgaagcttgg gcaataaaac aaagaaaatc
     7321 tacctcggtc acctaagcca ggagaacaat atcaaagaat tagcacacat gacaatggtc
     7381 aatcagctag caatggcaga tttaggtgtt ggaacagatt ttactgttca tgacacctca
     7441 ccagataccg cctgtccctt gacagacatc tagccttatg acttcacccc tgcttgt
//
LOCUS       DARYLD010000080         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYLD010000080 DARYLD010000000
VERSION     DARYLD010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(25..486)
                     /locus_tag="TU651_001796"
     CDS             complement(25..486)
                     /locus_tag="TU651_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL0897759.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TU651_001797"
     CDS             complement(530..1606)
                     /locus_tag="TU651_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL0897760.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU651_001798"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TU651_001798"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL0897761.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TU651_001799"
     CDS             4915..5859
                     /locus_tag="TU651_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL0897762.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            6118..6768
                     /locus_tag="TU651_001800"
     CDS             6118..6768
                     /locus_tag="TU651_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL0897763.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1997 a         1792 c         1335 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attgccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYLD010000081         6802 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYLD010000081 DARYLD010000000
VERSION     DARYLD010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..692)
                     /locus_tag="TU651_001801"
     CDS             complement(<1..692)
                     /locus_tag="TU651_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HEL0897764.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLAT"
     gene            complement(819..2435)
                     /locus_tag="TU651_001802"
     CDS             complement(819..2435)
                     /locus_tag="TU651_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL0897765.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(2851..4395)
                     /locus_tag="TU651_001803"
     CDS             complement(2851..4395)
                     /locus_tag="TU651_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL0897766.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDIEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(4564..5259)
                     /locus_tag="TU651_001804"
     CDS             complement(4564..5259)
                     /locus_tag="TU651_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL0897767.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(5343..6728)
                     /locus_tag="TU651_001805"
     CDS             complement(5343..6728)
                     /locus_tag="TU651_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL0897768.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2026 a         1625 c         1262 g         1889 t
ORIGIN      
        1 gtcgctaaaa aaatagagcc taaaatgaaa ataccccgat gattttccgg actaaccaat
       61 aagtgcagcg cataataggg attgatagcc tttaggattt ccaaatgctg taagctattc
      121 aagagaccac tgatccccaa aacgctaaac caaaccagca tgactggccc aaataattta
      181 ccaataacac ccgttccaaa gcgctgcagg ccaaacaaga ccatcaatat cagcaaggtc
      241 gttaggatca cattggtctg attctggtaa atactgctga gctcaggaac agcctttaag
      301 ccttcaatgg ctgatgtgac cgtaacagct ggtgtcaagg caccatctga taagagcgtt
      361 gctcccccaa gcatagctgg aatgattaac caccttgaca tccttctaac taaggtaaag
      421 agtgaaaaaa tccctccctc atgatgatta tcagccttta aagcaatcaa aacatacttg
      481 attgtcgtta ccaaggttag agtccaaata atcaaggata ctgagcctaa aataaaagct
      541 tcagacacct gtgaaaggcc gccttgattg tcaaccaacg actgcatggt atacagtgga
      601 cttgtgccaa tatcaccata gacaattcct agtgcaataa taaaacctgc ctttgttgct
      661 ttatcaaagg catcatgatg ggcattagac atcccaatgt tcctcctaag acttaatcat
      721 gccaaatgga ctgagaccat tatagcaaaa tctataacaa aatcaatatt ttcagaaaat
      781 taaaaagaga gctgacaatc atcagctctc ttgaaacttt agttcccttt atgacggata
      841 ataaatccag acgtcttagc ttcgacagcc ttgcccttct tgtgcaggtc cttgttagag
      901 cgtttttgct ttcgcttaaa gtcatagcta ccactgctat catgactgtc acgtttatca
      961 cgccttggac ggcggtcacc atcataaaca tttcttttct catgacgata gccacctcga
     1021 cggttatcac gaccgctacg actacgattg ccacgacctg tcttgccatt tttattgcca
     1081 tgaccaccac caacatactt aaacggtaat ggcttttcac gcgctatctc aacctctggt
     1141 aaggtatctg gatcttggac ggtcaagcta aggatataga gcgctagctc ctctggggta
     1201 aactctgctg ccaatttcat cgcatcgccc ttaaatttct caaagtttga gcgaatagca
     1261 tcatctgcaa aatcacgctc aatttttttg agggcaacct ttttcttagc ctgaaaggct
     1321 tcctctgccg tagctggctt gagtggcttc atgcgcttct tagtcaggtg ctcaatcatg
     1381 gtcagatagc ccatctcatt tggtgagaca aaggtaatgg attcccctga cttacctgca
     1441 cgaccggtcc ggccaatacg gtgcacatag ctttctggat cctgtgtaat atcgtaattg
     1501 tacacatgag taacgcctga aatatcaagc ccacgcgcag caacatcggt tgccactaaa
     1561 atatcaagtt gatcattttt aaagtcgcgt atgacacgaa ggcgcttatt ttggtcaagg
     1621 tcaccatgta tcccttctgc gcgaaaacca cgcaatttta agccgcgcgt gatttcatca
     1681 acacgacgct ttgtgcgacc aaatacaatt gatagctctg gctgctgaac gtccatcaga
     1741 cgtgtcatgg tatcaaattt ttcttgctcc ttaacacgca catagtattg atcaacattc
     1801 acatttgtta attccttgtt tttaacctga acatgctcag gatccttcat aaacttgaca
     1861 ccaatttcct tgattggagc tggcattgtt gctgaaaata acagggtttg acgatcgtca
     1921 gggacacgac taataatcgc ttcaatgtcc tctaaaaatc ccatattcaa gcattcatca
     1981 gcttcatcta aaatgagtgt ctcaacatgg tctagcctca aggccttacg cttaatcaaa
     2041 tctaacagac gtcctggcgt tccaacaacg acatgcgccc cagactttag ggccttaatt
     2101 tgcttctcaa tgcttgagcc accatatact gagcgaacct tgacgccttt atcacgacca
     2161 aaacggaaca gctcttcctg actttggaca gccagctcac gcgtcggagc aatcaccaat
     2221 gcctgaatgg tgttatcggc tgtacgaatc ttattcagag ttggtagacc aaaggctgct
     2281 gtttttcctg ttcctgtctg agcctgtccg ataacatctc gtccctccaa ggctaacgga
     2341 atggtcagct cctgaatagg agaggctttt tcaaagcctg ctgtaacaac agctgactga
     2401 atatcttctg ataagttaaa tgctgtaaat ttcaattgtt tctcttttct aaaaaggcag
     2461 tgcgaagctg ccttataaac cttttaatat tgtcgttcga ttaacaacct atttagtgta
     2521 acataattaa tattaaaaag ataggaaata agccatgaaa gtgtttttat ctcaaaatga
     2581 ttaacactat caggcagcta aattgataaa agcgtcactc cttattgctg attggctaac
     2641 agcctcaaaa aggcctcgtc ggacttgctt acctatgctt tttatctact ctgctaaaaa
     2701 gactcggcac agagacgagc cttcgcgatt ccatcaccaa tcttcaaaga cagcaattag
     2761 gattcctgaa agctccttat gccaatagcc tgccttttct tagcagcaga agtgcaaaaa
     2821 cggactaggt tcccctaatc cgcttagctg ctacattttt gcttctagct taacatctgg
     2881 gtatttatct gcaaaccaac gaagcgcaaa gtcattttca aagagaaaaa caggctgatc
     2941 aaagcgatcc cttgccaaaa tgtttcggct tgaggacatg cgttggtcca aatcctcctc
     3001 tgagatccaa cgaacagtct ttttgcccat tggtgtcatg atgacctctg cattgtactc
     3061 accctccata cggtgcttga aaacctcaaa ctgcagctga ccaactgcgc ccagcatgta
     3121 ttcacctgtc tgataattct tataaagctg aacagccccc tcctgtacaa gctgctcaat
     3181 acctttgtgg aaagattttt gcttcatgac attcttaggt gcaaccttca taaaaatctc
     3241 tggggtaaag gtcggcaatg gctcaaattc aaacaggttt ttactaacgc tcaaggtatc
     3301 tccaacctga taagtccctg tatcgtagac cccaataata tcaccggcaa ctgcattttg
     3361 gacattttca cgagactcag ccataaactg agtaacattt gatagcttaa cgcttttacc
     3421 tgtacgagac agctttacag ccattccctt ttgaaactct ccagagacaa tacgcacaaa
     3481 ggcaatgcgg tcacgatgct tagggtccat gttagcctga atcttaaaga caaagcctga
     3541 aaaatcctga ttgaggggat caatcatctg gtccgttgtc gtcttatgcc catgaggctc
     3601 tggtgcaaag gctaaaaagg tatctaaaaa ggtttgtacc ccaaaatttg ttaaggcaga
     3661 gccaaagaat accggagtca gctgaccatc taaaatagcc tgctctgaaa agtcattacc
     3721 tgcctcctcc aagagctcaa tatcttcaag cacctgctca taaaaagggt tgctggcaaa
     3781 aatccttgcc ccctcctcta aatcagcaaa cctctgctcc cccttataaa gctccaagcg
     3841 tttgttgtgc aaatcataca gaccttcaaa ggctcgtccc ataccaattg gccagttcat
     3901 ggggtaagaa gcaatcccaa gaacctcttc tagctcctcc aacaactcca aaggctcacg
     3961 tccatcacga tctaatttat taataaacgt aaaaacaggt atgttacgat gcttaacaac
     4021 ctcaaagagc tttttcgtct gtgcttcgat ccctttagcc gaatcaacaa ccatcacagc
     4081 agcatcaact gccattaagg tacgataagt atcctctgaa aagtcctcgt gaccaggtgt
     4141 atctaaaata ttgatacgct taccagcata atcaaactgc atgactgatg atgtgactga
     4201 aatcccacgt tgcttttcaa tatccatcca atctgactta gcaaattgac cagatttttt
     4261 tcctttaacg gtcccagcct cacgaatctc accaccaaaa taaagtaact gttctgtaat
     4321 agttgtttta ccagcatctg ggtgactgat aatcgcaaag gttcgacgct ttttaatttc
     4381 ttctgtaatt gacattcttt tttccttatt tgttcacatt gcagagcaag actctgatta
     4441 atagcttcaa gtcacacgtc acagttatgt ctacatgatc tcactcctaa atactgatat
     4501 gataaaaaga gctgctagag cagctccttt attatagctg attcgaagcg ctttttcaac
     4561 gccctatctt tctttagaga gcttcagctc taactgattg gcctcactaa atctcacata
     4621 gataagttca atcagcttaa ttaaaccagt caaccccatt gtcacaatga caaaattcat
     4681 aagcaggtga tgcgtatgaa taatcggaat atccatcaca aagccgtaat ttccctttgt
     4741 tgccaaattg atcaatacta aaacaaaatt aatggttgcc aagtaacggc aaacaaggac
     4801 tggctttagc tgacttggat tgtaaaaccg cagcaggtaa accaagccat tgaccaaaag
     4861 agcataatgc cccaggtaaa aagaaatatt agccacatgc catagctgat aagggtataa
     4921 atcaggtgat aacagggcca aaaaggtccc accaatccct aaaaccataa aaagctgctt
     4981 taagctactg cgatccggta agaaaaagat agctagcatg gccattcggc aatggtaaag
     5041 cggcaaagcc tctgtcaacg gaaagcctcg caaggcatac cagctataca aaccaaccaa
     5101 ttggaccaac tgaagcccta agaagatata gcgatacgac tttagctgat agagctgcag
     5161 ggtcataaaa accaaaaacg gcgctatcat caccgacaat agataaaata gcaaggacac
     5221 atgcggtagc ccaataggtt caattgcaaa aaaattcata aacatccctt tctacatttt
     5281 ttcattatac cttaatctta atgagaggac aagatgtttc atgtgttttt tctgaaaaag
     5341 tgttaggagg acttcccagc atgaggagct gtcaggcgat caaccacatt tgctagcagc
     5401 atggagtggc tgccctttag cagcatctgg tcattaggct caagaatagt caacaggtac
     5461 tggcacatgt cctcgtattg atcctctcga ttattctttt taaagaagct aactctgcca
     5521 cttggataat cttgactagc tagcttggcc aaggcttgaa tatcatcacc gtaaaagacc
     5581 aattgatcaa tacgcttggg atctaagctg gtaatcagct gagaatgcaa agcaactgag
     5641 tcagcaccta attccttcat atcagctaaa acagctattt ttttgccatt agggttggcc
     5701 ggaatggcag caaaggtttc caaaattaac cgcatagcag ttggattggc attgtacaca
     5761 tctgccaaaa ggtcggcgcc attagccgcc ttgacccact cggttcggtg gcgtgtcagc
     5821 ttgacggttt ctaaagcttc tataatatcc tcatcaggca cagccaagag tttaccaaca
     5881 taagctgcta tcatagcatt ggttgcattg tattttccag ttaagggaag agtgaccggt
     5941 cttggtaaga cattagtcct aaaggtcaag gagtccttgc actctttgat atcctcaacc
     6001 accagctctt gatgatcgcc aaagcgaatg accatctgac tatccggcaa atatggatca
     6061 aggataggat caccaggagc aattaaaatc ccgttagagt ccatcccatc aacgatttgc
     6121 attttccctt cggcaatctt ctcgcgagag ccaaagtagg ctaagtgagc ctcaccaata
     6181 agggttagca atgcaatatg aggtctggca attctagaga gcagctgaat gtctcccata
     6241 tgatcctgcc ccatctctaa aacaatcttc tcagtatcct ctggcatgtg aagcaccgta
     6301 taaggcaagc caatgtcatt attataattg ccctgggttt tgtaggtctt ataagctttt
     6361 gccaggaccg cttcaatcat atccttggtt gatgttttac cgtttgagcc tgttacagca
     6421 atgacatcga cacgtagctt atcaatataa tactgggcta atttttgaaa ggcagccaag
     6481 caattctcaa ctagtatata gggtctgcca ctgattgctc tttctgaaaa ggtagctacg
     6541 gccccatttt caaaggctaa gtcaataaaa tcatggccat ctcgctcacc ctgtagcggt
     6601 aaaaaaagat caccttttgt gatgtttcta ctgtcaaatt caatctgatt cagaggaacg
     6661 tcgtctaaat cagaaagact attttgagca tcaacaactc ttgccacttc atgtaatgtt
     6721 aatttcatct tatttttcct cttaaaacac tggtttttaa agctttgctt atattatagc
     6781 ataacatatt aggaatattc tt
//
LOCUS       DARYLD010000082         6698 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYLD010000082 DARYLD010000000
VERSION     DARYLD010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6698
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            85..366
                     /locus_tag="TU651_001806"
     CDS             85..366
                     /locus_tag="TU651_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL0897769.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
     gene            complement(492..917)
                     /locus_tag="TU651_001807"
     CDS             complement(492..917)
                     /locus_tag="TU651_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL0897770.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(914..1318)
                     /locus_tag="TU651_001808"
     CDS             complement(914..1318)
                     /locus_tag="TU651_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL0897771.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            complement(1340..2119)
                     /locus_tag="TU651_001809"
     CDS             complement(1340..2119)
                     /locus_tag="TU651_001809"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL0897772.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            complement(2116..3048)
                     /locus_tag="TU651_001810"
     CDS             complement(2116..3048)
                     /locus_tag="TU651_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL0897773.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            complement(3326..3598)
                     /locus_tag="TU651_001811"
     CDS             complement(3326..3598)
                     /locus_tag="TU651_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL0897774.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            complement(3662..4099)
                     /locus_tag="TU651_001812"
     CDS             complement(3662..4099)
                     /locus_tag="TU651_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL0897775.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            complement(4086..6218)
                     /locus_tag="TU651_001813"
     CDS             complement(4086..6218)
                     /locus_tag="TU651_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL0897776.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            complement(6386..>6698)
                     /locus_tag="TU651_001814"
     CDS             complement(6386..>6698)
                     /locus_tag="TU651_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897777.1"
                     /translation="LTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLSAARWG
                     SRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELEELEDL
                     T"
BASE COUNT         1930 a         1624 c         1251 g         1893 t
ORIGIN      
        1 aacgagaagc cttcaaaaaa aaagatgaca accatcagct tttatggtaa aatggttggg
       61 tatcttacgg gaaaggagag gactatgcct acaccattgg agcagcggca gctcaagcag
      121 cagaagcaag agcaggtctc gcagcaaaaa tttcaagagt ttcaagacct caatggacac
      181 agtagcaagc tcaaggaact tatttttttt gcccgtattg ctgtttttag tttaatcact
      241 gtcttgtttg catttgtcct tcttgtcatg aatttggcac cggtttgggc ctttctaatt
      301 gctagtgcta tcagcctagc catcacttcc tttctttcaa aggccatcac gttattaatg
      361 tcataaacag ttagagcttg gcttcgctaa gctctttttt cattactctt attgcctatt
      421 ttcttgaata aacgagtagc ccacatcaca aaaggccctc catagctgag agagccctta
      481 tttttgcctt attattcttc agacttattg ctagctgctt ctttttctga atcatcttca
      541 ggatagttga taataatatc ctcttcatcc agatcaataa tcacatcatc agccttgtca
      601 tgctctgaag cagcttcctt tgcctgatga acaaattggc tggtcttttc cttgataaaa
      661 tcaaacacct gatcagtggt catatcccct gattcaaacc tggtttttaa atcattaaag
      721 gtatggcgag ccagctgact gtactcactt cctttttctt tagccatttg atgatattcc
      781 tcaggatttt gacgataggc ttcataggcc ctttgtgcgc gagccttcaa gacctttcct
      841 ttttcagttg acaagaaata agcggtagct gctcctgaag ctacaccaat caccaacgtt
      901 ttaaaaaaat tactcatgac cttttctcct ttttaccaaa taatttagaa gcgaccttgc
      961 cgacaagagc tactttaccc acctttgcag cattgcttgt ggcatttgtc gcccgacgtc
     1021 caaggtgtct ggcctgcaca ttcaaatcag aaacactttc tgacaaatct gcaatagcaa
     1081 caaagagagg atctattgtt gtcatcttac cattcacatc atctaccagc acattagcct
     1141 tagctaatat ttcattggtt tgataaaggg taacattgac atcactcgtt aaaacggtaa
     1201 tggttttttt agcctcatca actgcctctg acaccttttt taacaccaca atcaaaaaaa
     1261 taaccagagc aacaaaggct aatgcgatta tcagcaatga aatgcccact aaattcataa
     1321 acgtctcctc tttctatccc tattcttgat aataagaaat tcccttttgt cgatgccttt
     1381 taaagataaa aacaatcgca atgataatga gcagcaccga catgtattga gaaacacgaa
     1441 ttcctaaaag catcaggctg tccgttcgca tgccctcaat caccaatcga ccacagccat
     1501 accaaatcag gtaaaatgag ataatatccc catctactaa tgacctgggc ttacgccgcc
     1561 acaccatgat aatgacaaag ccaatcaggt tccacatgga ctcatataaa aaggtgggaa
     1621 cacgatagct gccatctata aacatctgct ggcgaataaa actaggcagg taattgagct
     1681 ggctgacagc cctgccatag gcctcttggt taaagaaatt tccccatctg ccgatggcct
     1741 gagcaagcat gacactaggc gctgcaatat ctaagaaatg gataggattc agcaccttat
     1801 agtagcaata aacaaagaga acaatggtac ctgttatcaa gccgccatag atggcaatcc
     1861 caccattcca aatagcaaag atatcactca aatgctgaga ataataggac cattcaaagg
     1921 ctacataata gattcttgct ccaataattg ccaaaggaaa ggcaatcaga ataaaatcaa
     1981 taatatcatc actggtcatt ttttttcgcg gggcttcttt ggctgccaaa taaaccgcta
     2041 aaagtaatcc caccaagata caaaccgcat accagtgaag actaagagga ccaagcttaa
     2101 aggctattgg attgatcatt tgccctcctc atttttgctg attaaacgtg taaggcgctc
     2161 ctcaaaggtt ttggtagcat caaagcccat ctctttcgca cgatggttca tggcagcagc
     2221 ctcaataacc actgacacat ttcgacctgt tttgacagga atgcgaatcc ttggaatact
     2281 gacaccagaa aaggtaatct cttcattgcc attgcccaag cggtcaaaga ccttgccagc
     2341 ctcaaaattc tccaaataaa tagccaactg cacctgtgag gaatccttga cagcactagc
     2401 accgtacagc gacatgacat caataatgcc aacaccacga atctcaagga gatgacgtaa
     2461 aatctctgct ggctcccccc atagcgtctc ctcatcttta gcaaagacat ctactcggtc
     2521 gtctgccacc aagcgatggc cacgcttgac caactctaag cctgtctcac ttttaccaat
     2581 acctgaatca ccttggatca gcacccccat accgtaaata tccatcagca ccccatgcac
     2641 acttgttcgc tctgctaagg aagcatcaag aaaataagac atctcaccag ctaagcggct
     2701 ggtagatacg cggctgctaa acagagcaat accttcctcc tgcgctgcct gaaccatctc
     2761 ctctgggata gctaggcccc tagatacaat cacagctggc gtgtcttttt taaacatttc
     2821 ctttaagact gagtagcgat tgtgtgaggt catctgagtg aggtaggacc attctttcat
     2881 gccaaacagc tgaagccgct ctggggcata gtaatcaaaa tagccggtca tctcaagacc
     2941 cggacgcgaa atatctgagg tcgttatctc cttttctagc aagtcatcag ttgcatagac
     3001 aacgtcaagc ttgacctttg tgactaacat cttaacggta actgtcataa tttctccttt
     3061 tttaatatta tatcataaat cactatctaa gcccttacaa atacttattt ttcaaagaag
     3121 ctttcaaagt gcttgatcat actaaaaaag aatcctgcaa cagctgcctc aggctcactt
     3181 aaagcaggca ctagcctaaa gcggacaaac aacaaaaggc cctatctcat cagataaagg
     3241 cctacagcca gctttatttc tgataatcac gctagaggca ctattaaaat tcctgtcaag
     3301 cttttaatag tcgctcgctg tggtcttacc aaaaccagcc ttcatcttca tcatttagga
     3361 catcagcatc cttgcgacgt cttggtcctc tcccgtaacg ttcttcaagt aggtcctctt
     3421 tatatggtag gaagatggct aaaagaatat aaataacaac cccaaagcga gtaaaataga
     3481 tcaataaggc ggcaagcaca cgagctaggg gcaaatccca gccgtattta tcagctaaac
     3541 cagagataac tccagccact agcttatgct ttcgttgctt ataaaattta gattccatgt
     3601 ctcctcgcct ccttattcta tgatactagt ttattccttt tttagcaaaa taaaatcagc
     3661 cttacgactg atttttttca atgagcctgc catgacacct gccgcaggca aataccgcca
     3721 gattgatagg acgttttcgg tcataagctt ggccgcaatc ttgacagatg tagaggtaat
     3781 tagcttgatg tgactgtaat tttggagcgt atctcagacc gtctacttgg tctagaagct
     3841 ccttaaaggc ttgatcctta tgccgaaagc ccagcccctc aaaatagagg tgataatgac
     3901 aaagctcatg cctaacgatc tgtctaaaga cagtctcccc atgctcctct aagattttgg
     3961 gattgaaatc cagatgacca tcctttggaa aaaaacgtcc gcctgttgtt cttagtcgtc
     4021 tgttccaaga agcctgatgc ttaaagggct ttccaaaatc agctagcgag acctctctaa
     4081 cataatcagt cagactcacg aggcggcact aagcttaggt tgaccttgtg gcggtctaag
     4141 tcaaccttag aaacccaaac agtgactaaa tctccgacag aaacgacctg acttgggtga
     4201 ttgacaaagg cctcactcat ctctgaaatg tgaatcaaac cgtcctcatg tacaccaata
     4261 tcaacaaaag caccgaagtc aaccacattt ctaacagttc cctctagcct ttgaccaaca
     4321 gccagatcct ttacactcaa aatgtccttt cgaagaacag gagcttcaaa gtcatcacgc
     4381 aagtctcttc ctggcttcag caaatcagca atgatatcct tgagcgtttc ttgaccaagc
     4441 gtcaattgct ctgccatttc ctcaagatta accgcctgta atttggccct tgcaggctca
     4501 tctaagtctt taatcgcaag taattgaaag agctttttga cagccggata ggcttctggg
     4561 tgaacgcctg tattgtctaa tatattctta gcattgggaa tacgcaagaa gcctgctgcc
     4621 tgctcaaagg cctttgcgcc tagtctaggg acctttttga tctcagcacg tgaggtgatc
     4681 tctccatttt cttcacgata cctgacgata ttctcagaaa tggttttatt tagccctgaa
     4741 acatgagcca gtagggctgg actagctgta ttgatgttaa ccccaacctg attaacaacg
     4801 gtatcaacga caaaatccag atgctcagat agctttttct gactaacatc atgctggtat
     4861 tgtccgacac cgattgcttt tgggtcaatt ttgaccagct ctgctagcgg gtcttgcaag
     4921 cgacgcgcaa tagagatggc tgagcgcttt tcaaccgtca gctctggaaa ttcatggcgg
     4981 gctagctctg aggccgaata aaccgaagct ccgctttcat taacaatgac ataagaggtt
     5041 tctggaaaat cctttagcac ctctgcaaca aaggcttcac tctcacgact ggctgtgcca
     5101 ttaccaatgg caataatatc aatctgatag tcagtgatga gctgagctag agctactctt
     5161 gctgcttgaa tcttagcttg attagctggt gccaccggat agataacctg agtagttaac
     5221 agctttccag tcggatcaat caccgctaat ttggcccctg tcctaaaggc cgggtcaaag
     5281 cccagcacca tttttccctt tagtggtgaa attagcaaaa gatgacgcaa attttccgaa
     5341 aagagcttga tagcaccgtc ctcagccatt tcagttaatt ctgtgcggat acgtcgttcc
     5401 atagcaggaa caattttttt cttgattgtt tggttaataa catcatcaat ataagcattg
     5461 tgctccttaa agcgaaggct gaaaaagcgc agcattttgt ctatatgatg ctcaaaggat
     5521 acctttaata cgcctagctt ttccccacga ttgagagcta gggtcctgta gccctgcatg
     5581 ttagataccg tctcagaaaa cgcatagtaa atctgaaaga cctgcttgtc atctaagctg
     5641 gcttccttta ggctagaggt tatacggcta tacttccaaa tctcattata ggtccaggac
     5701 cttagcctgc tatcctctga catggcttcg accaaaatat caacagctcc agcaagggct
     5761 gcctgtggat ccgaaaaacc ttctgtgata aaggcctctg ccttagtttc taggtcttgt
     5821 gcattttgaa ggatcagtct agctagtcca gataagccgg cttctcgagc aatggttgcc
     5881 ttggtacgcc gcttttcctt gtaaggcaaa taaagctcct ctaggtcagc caatttatca
     5941 gctgcttcta tagcttcctt aagggcagct gttagtttcc cttgtccttc gattttagca
     6001 agaatggtgt ctttacgctc cctaagctgt gtgagggact tatccatatc aataatggcc
     6061 ttgatcacca cttcatcaag gttacctgta gcttccttac gatagcgcgc aataaaggga
     6121 atggtattac cctcagcggt aagggtaagc acttgactaa tctgttttgg ggtgaccccc
     6181 aacgcttctg aaatgttttg atgattcata ttttccataa cagttcttat tatagcacaa
     6241 agaaagaggg atagaacaag ataaaagctt tatgacaaat aagtgtcaag aaaacaaaac
     6301 ttatcttttc agatacttct aaaggctaag aaaaaacgat ctccaaacgg aaatcgtctt
     6361 ttagctactt agtggttagt caaaattaag tgagatcttc taactcttcc aactcctttt
     6421 caaacttatt ataaagttca tcaatttcac ttactgattt tgctgcacct accctagctc
     6481 tgaattgtct gttataagac ctaaagccat cctctcctag tttatgctta aatcgtgtta
     6541 acagattaag gatttgcagt cttgaccccc agcgcgctgc actaagcgac ttggtgtcgt
     6601 taatcgtatg ctctataaca tgcccacgag aaaacgcctc tacttttgtt gtgctaactg
     6661 ctactgttgc taaggctagc gctgcagcac tagttaat
//
LOCUS       DARYLD010000083         6502 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYLD010000083 DARYLD010000000
VERSION     DARYLD010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6502
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(303..683)
                     /locus_tag="TU651_001815"
     CDS             complement(303..683)
                     /locus_tag="TU651_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL0897778.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(717..1709)
                     /locus_tag="TU651_001816"
     CDS             complement(717..1709)
                     /locus_tag="TU651_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL0897779.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(1725..2270)
                     /gene="srlA"
                     /locus_tag="TU651_001817"
     CDS             complement(1725..2270)
                     /gene="srlA"
                     /locus_tag="TU651_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL0897780.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(2406..2867)
                     /locus_tag="TU651_001818"
     CDS             complement(2406..2867)
                     /locus_tag="TU651_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL0897781.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(2867..4639)
                     /locus_tag="TU651_001819"
     CDS             complement(2867..4639)
                     /locus_tag="TU651_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL0897782.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(4933..6282)
                     /locus_tag="TU651_001820"
     CDS             complement(4933..6282)
                     /locus_tag="TU651_001820"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL0897783.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
BASE COUNT         1901 a         1553 c         1300 g         1748 t
ORIGIN      
        1 catggaattt aaatggtgga ataaattagc tatatctcta acatctttat atattattta
       61 tcaaatgctg aaaaaggata aattaattaa ataatcaact aatgtacaag ttgtctttaa
      121 gctgaaaaga ggctatcaac agcctctttt tttgatgata tagataagcc caatgcttcc
      181 ttagaagagc tcttctgtga gatgacctta tcacctgaca ttagctgctt ggctcatgcc
      241 tacagctaaa ggaaatgccc tgcaaggata gcagcactta gcctgctggt ctacggcgtg
      301 tctcagctgc acctaagcca agcaaagatt tgtactaggc tgccctgcct gacctgtggc
      361 agccctttgc ccttgacatg cagagtaccg ggaagagagc tggctgtgga gccatcaaaa
      421 gaaatggtta tatgccctag ctgagcaaga tttttttcaa caacagcacc tactgctgtg
      481 atgtcatatg ccatttgatc aatgactagc tgaccaccag cagagataga cccagacact
      541 tgcttgttgt caatcgtata gcaaaagtct gccaagtctg ccggtgctcc ctgatcaaaa
      601 agaataagca tattggcagc actaatcatg tctgccgcct ccgatccaat agcggtaact
      661 cttgtttcaa atacttttat catacattct ctctcttcct atcatacgat agctccttac
      721 tgatacaaac caatacttgc aatccaagca acaacaaccc gaggaacacc atttaaaaag
      781 cgtgaataaa gcacagatgg caccccaacc tctactgtct cagcattagc ctctgataaa
      841 ccaagcgcta ctggaatgaa atcacagcca ttttgcgtat taatagcaaa aagtgcagga
      901 agagccattt gtggtggaat agtgcctttt ccaatctcaa caccaatgag cgttccgatg
      961 atttgactaa taaccgcacc aggtcctaac agcggtgata aaaatggcaa cgaacagata
     1021 aagccaatga taatcaagcc ccaaatatta ccagccagcg gtaccatgag cttggctagc
     1081 caattaccaa caccagagcc ttggataaaa ccaattaaaa gagagacaaa tgccatgaat
     1141 ggcaaaatcg tattgattaa ggtctggata gcctcacgcg ccgcttggtt gaagatagca
     1201 actaccttac ctgctcccat accaatgcgg gcaacaaagc tgctttctgc gcgctgctca
     1261 gtaatctttt tgctagtatc atagctgcta gcctttggaa ctgatgactc cttagcacta
     1321 gcaacatgag cctgagcgtc actggctgtg atttgctcaa gacctacagc agacacgtaa
     1381 atgtcctcgg taatgtactg tgccaaggga ccgcttttac ctgtcgccac gatattaatg
     1441 gttggaatgc cttttttagg gtaaataccg cagcgtaggg tgccgccaca atccacaata
     1501 gctagggcta tctcatcatc agggattgag gtcacaaagc cattgaccgc ctccatacct
     1561 gttagggcag caattttatc gacaatgtca ggcttttttc caccgccagt aatatagata
     1621 aatttgtgct tagcttctgt tggtgtaatg gttagcggcc caccatagcc accgctcccc
     1681 ttaacaactg taatactgtg ataagtcatc atgctacctc tcttctataa ttcaatcatc
     1741 ttacttaatg tcacaccctg ctgcttggcc acgtaggctg tcgtaaagtc agttacccag
     1801 ccaccaacaa agttcatgat taacccaacc aagaggtaac gaatcgccaa gtccatttgg
     1861 ctcaagccta gcgtcttgat acctgaggca atacctaacc agacaaacaa ttctcccgga
     1921 ttaatgtgtg gaaagacacc gtttgacgta tgacaaaatt gcatttgagc ggcaacatag
     1981 cttggcttgt aatactcggg cataaagcgt cccatgctga ttgccatcgg attacccagc
     2041 ataaaagctg aaataaaagg caataccatg tagcgactga tagggttttt agcagagatt
     2101 tttgccaatt gattgaccct ttgatctcct aaaataccaa ttaaggcatt cattgcaacc
     2161 agcagcatca agaccaccgg cacaatgcca gtcatccagc tgacaaaggt ttcaccacca
     2221 agctggaaga gcttcataaa gccttccgca aatcttgtta tcatttccat aaataaactc
     2281 ctcatatgat gtacttacaa gcaagacaat acaaatgtac tgcctgcttg ataatagctg
     2341 cttgagctgg actcaaaaca gcttttatgt tgacaaggca agcaatcaat cctgcttttg
     2401 gcaccttact tgaagcgtgc cagcagctgc ttggcctgta gggtccaatc aaaggctgag
     2461 gcatattttg gtgcgtcctc atagacccct gcctcaaccc tcaagaagac ctctcttgcg
     2521 tcctcaatag ccaagcgcag caatttattt tctcgtctaa tcaagggatt gtagcgatca
     2581 aaataatgaa tatcctgacc gatataagct ggcattggct taaacctggc tgccactgtc
     2641 acaccctgca tttgcctagc atctaatacc ttacctgact gatccaaggc aaacatgaca
     2701 atggttccgg ccctgatttt cccggctcta cggccaatag caacgcgccc ctgtcgtcta
     2761 agactggcat aaacagcatt gaagtgctta agctgtctca gacctagcaa taattgaaaa
     2821 aggtaagcaa ctatgacaaa tagtccaaaa ataaccataa aactcattaa aaaactcctt
     2881 tttccttggt aaatgcaata aactcagctt gactttttag gctccttagc tccgcctgaa
     2941 gcttatcatc gcttgctatt ttgaaaatat catcataaat tttcaagaga tcagcctcca
     3001 tctgcgcttc aaccctcttg gaaatagcca ctagaaaaat aaactccacc agacagtcat
     3061 gctcacgata aggctcgtct aatagaccca gcagcaggac agtctttgtt tccttgtcat
     3121 taatcgtatg tggaaaggca atgcgattgc caaataaggt tgattgcagg gcctcacgct
     3181 ctagcaggcg ttgaccaaac tgcctgtcaa ccagctgctt ttcctcaagc agctccgcca
     3241 tttcagtcag gtagtcagtg taggccttcc cctttgacag acgagcaaag tgtagggtga
     3301 tggtcgccag gtttttctgg tgataatgat gtaccctgcg ccattcattt tgcagccact
     3361 ggtcatcaaa cagatttgtg atttggagaa caggagattt tagctgacca aacttcagcg
     3421 gcacagtggt gaatatggca aaatagtgat cattgtcatc aggattgaat tgctcctcag
     3481 agaattgtga gatcaacaaa tcaggaccta gcaccttgct caagcgacga caaatcatat
     3541 tggcagtgcc acgacctgtc gtgcagacaa cggcaatttt tttcactgtt ggctctgtca
     3601 catgctcagc gtctttcatc atcatttcga aataaagggc caaatagcta cactcagaca
     3661 attctatggc gcagtcaaac tcctctgcta agacctgagc tgcgacaatg gccatatcaa
     3721 aggccaaggg gtatttgtat ctaatttctc catgaaaaat atcattggcc tgaacatgaa
     3781 aaatcaaacg attcaccaag agcttcaaat gcgtatgcaa agcaacaaaa agcttgtctt
     3841 ggtcaatagt caccaagaga ctggtcttga tgtgctcaat catttttgaa taaagcctga
     3901 caatgctctg ttgcagaggc ttttcttgat aggctagatc ctcgatgtat tggatattca
     3961 agggaaagct aataaactgg cgctcgtatt gactcagtga cagctgatag gctagctcaa
     4021 tgtgatagac cagctcctcc ataaaggcac tggaatcaac ctcattgcta tagtaaggaa
     4081 taggatctgt cagatacctg ccctgacgca ttcgctcaat ggttatcgca aagctcttgg
     4141 tcaaaagctc ttggattttg cgaggaagct ggtaggtctg atacagctca tctagaaaaa
     4201 acaagctatc accacacaag ccctgcggct caaagtattt gtaaacctca tgaacataaa
     4261 gcagccgaag gttcaactca gtgccaacag cctgtatgcc atgattgggc ttgccctgaa
     4321 tcatgaccga ataggtccta gcaagagcct tggctgcctt taggtcttta ttgatcgtgc
     4381 tgcgactgac gccaatctca tcagccaaat catcaatgac taaagctgag gagctttgca
     4441 gtagcctttt tagaagataa gctacccgct tgctagcgga attaaagtca ctagccttac
     4501 gtaaactacc agctaatatc gtctctaatc tagcataatc atagacctgc agctgcaaaa
     4561 aggcgccttg ttgggtgatg gtcgcatctc catctaaaat gtcattgagc tgaccaatgc
     4621 tacttgcagc gtttgacatc gtcttttcac aaagtcacag cttagaaagc tagcagagga
     4681 gacaaaagca agaccttatc agctaacagc agcatattaa acgaacagct agtgatactg
     4741 atcctactaa gcatagagct ccaaaagcct ggcttaaata gtattcaaaa tagaacaaga
     4801 gctctcaaga acaataacct agcgcactac ttgccttgat aagcctaacc gaccttgaaa
     4861 agaagcaaaa aaaagagcct ctcacgagac tctttgttat gttttagcag actagtctag
     4921 ctagctctgt cattacaagc gtgcgttgag cgctgctcct agctcttcaa agcctggctt
     4981 accaagaagg gcaaacatgt ttttcttgta agcctcaaca cctggctgat caaatggatt
     5041 taccccattg aggtagcctg aaagggcaat agcaagctca aagaagtaga tcgtatagcc
     5101 tagtgtaaat tcgtcttgct ctggaagcgt gataaacata tttggcacac caccgtctgt
     5161 atgggcaaga aggacaccat ctgttgcttt tttgttgaca aagtcaacgt ctttgccttg
     5221 taggtagcca aggccatcaa gatcctcagc catttctggg ataatcacat tttgacgtgg
     5281 cttatccaca cgaatcactg tctcaaagag gttacggtag ccttcttgga taaattgacc
     5341 aagagaatgc aggtctgtcg agaaattagc tgaagttggg taaataccct tttggtcctt
     5401 tccttcagac tcaccagcca gttgcttcca ccattcgcta aaatactgca atgatggctc
     5461 atagtttgcc aaaatttcag ttacatagcc tttgcgatag aggatattgc gaactacagc
     5521 atattggtaa gcgatgtttt ctgagatttt atctgatgac aggtccttac gagctgcatt
     5581 tgccccctcc atcagcgcgg taatatcagc acccgatgct gcaattggca acaagcccac
     5641 agctgtcagc actgaaaaac gaccaccaac attatctggc acaacaaagg tttcccaatg
     5701 atttgcatca gcctcaacct taacagcacc cttgacctta tcagtcgttg catagatacg
     5761 cttgttggcc tcttcttgac cgtacttttt aacaagtaat tctttaaaga cacgaaaggc
     5821 gattgcaggc tctgttgttg taccagactt agaaatcacg ttaacagaga aatctttatc
     5881 ttgaacatag tccacaagat cagcaagata gcttgatgag atggagttcc cagcataaag
     5941 aatttgtggt gctttgcgct cttttgctgt ttgtaggttg gcaaaatggc tgttcaaaaa
     6001 gtcaatcgca gccttagcac caaggtaaga gccaccaata ccaatcacaa caagaacgtc
     6061 actgtcagcc ttaatcttct cagctgcttt aaggatacga gcaaattctt ctttgtcata
     6121 gttttcaggt aactcaagcc agcccaagaa atctgatcca ggtccagtgc cctgacgtag
     6181 tgcctgatca gcctctgtta cctgaccttg taaaaagtca atttcatgct gtccggcaaa
     6241 ttgctcaaga acctttgaat aatcaaatgt aatatgtgac attattttac tcccttaact
     6301 tttaaagttt cattagtatc ataacctttt ctattcaata tttcaatgtt ttttattttt
     6361 ggggagggtg gcctgacttt aacgacatga ggatcatttc tgtctaaaag cagctttgtg
     6421 atgagcctag cgcttcccta tctgcttcta ctatagctta ctggggctga tccgggtgat
     6481 gtggtagcct cttggcatag cc
//
LOCUS       DARYLD010000084         5362 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYLD010000084 DARYLD010000000
VERSION     DARYLD010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5362
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(150..389)
                     /locus_tag="TU651_001821"
     CDS             complement(150..389)
                     /locus_tag="TU651_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL0897784.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TU651_001822"
     CDS             complement(548..1036)
                     /locus_tag="TU651_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0897785.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TU651_001823"
     CDS             complement(1055..1345)
                     /locus_tag="TU651_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL0897786.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TU651_001824"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TU651_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL0897787.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5362
                     /locus_tag="TU651_001825"
     CDS             4640..>5362
                     /locus_tag="TU651_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL0897788.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDTPKPEPKPEPKPE"
BASE COUNT         1635 a         1177 c         1071 g         1479 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatacaccta agccagagcc
     5341 taagccagag cctaagccag ag
//
LOCUS       DARYLD010000085         5331 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYLD010000085 DARYLD010000000
VERSION     DARYLD010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            90..1643
                     /locus_tag="TU651_001826"
     rRNA            90..1643
                     /locus_tag="TU651_001826"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1865..1937
                     /locus_tag="TU651_001827"
     tRNA            1865..1937
                     /locus_tag="TU651_001827"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1898..1900,aa:Ala,seq:tgc)
     gene            2245..5144
                     /locus_tag="TU651_001828"
     rRNA            2245..5144
                     /locus_tag="TU651_001828"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5229..>5331
                     /gene="rrf"
                     /locus_tag="TU651_001829"
     rRNA            5229..>5331
                     /gene="rrf"
                     /locus_tag="TU651_001829"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1525 a         1083 c         1543 g         1180 t
ORIGIN      
        1 aagacgacct aaacgtgcgg gttacggaag taacctgtca ataaagaaac aagtcagtaa
       61 tgacgtcgag ttaagagctc aaacactgaa ttaacgagag tttgatcctg gctcaggacg
      121 aacgctggcg gcgtgcctaa tacatgcaag tggaacgcac agatgatacg tagcttgcta
      181 caattatctg tgagtcgcga acgggtgagt aacgcgtagg taacctagct tatagcgggg
      241 gataactatt ggaaacgata gctaataccg cataaaagtg gttgacccat gttaaccatt
      301 taaaaggagc aacagctcca ctatgagatg gacctgcgtt gtattagcta gttggtaggg
      361 taaaggccta ccaaggcgac gatacatagc cgacctgaga gggtgaacgg ccacactggg
      421 actgagacac ggcccagact cctacgggag gcagcagtag ggaatcttcg gcaatggggg
      481 gaaccctgac cgagcaacgc cgcgtgagtg aagaaggttt tcggatcgta aagctctgtt
      541 gttagagaag aacagtgatg ggagtggaaa gtccatcatg tgacggtaac taaccagaaa
      601 gggacggcta actacgtgcc agcagccgcg gtaatacgta ggtcccgagc gttgtccgga
      661 tttattgggc gtaaagcgag cgcaggcggt ttgataagtc tgaagttaaa ggcagtggct
      721 taaccattgt atgctttgga aactgttaaa cttgagtgca gaaggggaga gtggaattcc
      781 atgtgtagcg gtgaaatgcg tagatatatg gaggaacacc ggtggcgaaa gcggctctct
      841 ggtctgtaac tgacgctgag gctcgaaagc gtggggagca aacaggatta gataccctgg
      901 tagtccacgc cgtaaacgct gagtgctagg tgttaggccc tttccggggc ttagtgccgg
      961 agctaacgca ttaagcactc cgcctgggga gtacgaccgc aaggttgaaa ctcaaaggaa
     1021 ttgacggggg cccgcacaag cggtggagca tgtggtttaa ttcgaagcaa cgcgaagaac
     1081 cttaccaggt cttgacatcc cgatgctatt cttagagata agaagttact tcggtacatt
     1141 ggagacaggt ggtgcatggt tgtcgtcagc tcgtgtcgtg agatgttggg ttaagtcccg
     1201 caacgagcgc aacccttatt gttagttgcc atcattaagt tgggcactct agcgagactg
     1261 ccggtaataa accggaggaa ggtggggatg acgtcaaatc atcatgcccc ttatgacctg
     1321 ggctacacac gtgctacaat ggttggtaca acgagtcgca agccggtgac ggcaagctaa
     1381 tctctgaaag ccaatctcag ttcggattgt aggctgcaac tcgcctacat gaagtcggaa
     1441 tcgctagtaa tcgcggatca gcacgccgcg gtgaatacgt tcccgggcct tgtacacacc
     1501 gcccgtcaca ccacgagagt ttgtaacacc cgaagtcggt gaggtaaccg ttaaggagcc
     1561 agccgcctaa ggtgggatag atgattgggg tgaagtcgta acaaggtagc cgtatcggaa
     1621 ggtgcggctg gatcacctcc tttctaagga aaaaggaagc acgtttagcg tcttatttag
     1681 ttttgagagg tcttgaaata agtcatgaga acgttaagaa acccgtatga caatagggaa
     1741 ctgacgcaga gtcgtaggac tcaaggaagt gattcttttt cactagggtt ttagttcgaa
     1801 tacagtttgg cttcatacag accattgata agagtataca tatacaagta catttatagt
     1861 gtacggggcc ttagctcagc tgggagagcg cctgctttgc acgcaggagg tcagcggttc
     1921 gatcccgcta ggctccatta tctaggatac aaagagaagt ttgggttacc taattttctg
     1981 tattctaaga tatataagat atagttcaag taattgaaca cgacctcatt ttttaggaaa
     2041 aaagataaat ctcctcgtgt gtaaagcaca catcgtcgat ttcctatttt tctacaaaaa
     2101 tgcccaacaa gttgggacgg tcttagtatc ttaatcttgt ccattgaaaa ttgaataact
     2161 atatcatatt ccgcaatcaa aaaagattgt aagaaagtaa caagaaataa accgaaacgc
     2221 tgtgataacg agtttaaaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg
     2281 cactagaagc cgaagaagga cgtgacaaac gacgaaatgc tttggggagc tgtaagtaag
     2341 caaagatcca gagatgtccg aatgggggaa cccactagct aatggctagt atccataact
     2401 gttaaggtta tgagaaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag
     2461 aaagcaaacg cgattgcctg agtagcggcg agcgaaaagg caggagggca aaccgaagag
     2521 tttactcttc ggggttgtag gactgcgctg tgggacgaca agattataga agaaggcctt
     2581 gggaagggtc gccaaagaga gtaatagcct cgtattcgaa atagtcttta accctagcag
     2641 tatcctgagt acggcgagac acgaggaatc tcgtcggaat ctgggaggac catctcctaa
     2701 ccctaaatac tcactagtga ccgatagtga accagtaccg tgagggaaag gtgaaaagca
     2761 ccccgggagg ggagtgaaag agaacctgaa accgtgtgcc tacaagaagt tcgagcccgt
     2821 taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttta tgtgcgaggt
     2881 taagttgaag agacggagcc gaagggaaac cgagtcttaa tagggcgtaa gtacgtggac
     2941 gtagacccga aaccatgtga cctacccatg agcaggttga aggtgcggta agacgcactg
     3001 gaggaccgaa ccagggcacg ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt
     3061 ccaaacgaac ttggagatag ctggttctct ccgaaatagc tttagggcta gcgtcgatat
     3121 gaagtctctt ggaggtagag cactgtttgg gtgaggggtc catcccggat taccaatctc
     3181 agataaactc cgaatgccaa tgagatatga tcggcagtca gactgcgagt gctaagatcc
     3241 gtagtcgaaa gggaaacagc ccagaccacc agctaaggtc cccaaataac tgttaagtgg
     3301 aaaaggatgt ggggttgcac agacaactag gatgttagct tagaagcagc tattcattca
     3361 aagagtgcgt aatagctcac tagtcgagtg accctgcgcc gaaaatgtac cggggctaaa
     3421 acagtttacc gaagctgtgg attaccgtta aggtaatggt aggagagcgt tctatgtgtg
     3481 atgaaggtat actgtgaaga gtgctggaac gcatagaagt gagaatgccg gtatgagtag
     3541 cgaaagacag gtgagaatcc tgtccaccgt aagactaagg attccagggg aaggctcgtc
     3601 cgccctgggt tagtcgggac ctaaggagag accgaagggt gtatccgatg gacaacaggt
     3661 tgatattcct gtactagagt atatagtgat ggagggacgc agtaggctaa ctaaaccgga
     3721 cgactggaag agtccggcta agcagtgagg tgtgatgtga gtcaaatgct tacatctata
     3781 acattgagct gtgaagggga gcgaagttaa gtagcgaagt tagagacgtc acactgccaa
     3841 gaaaagcttc tagcgatacg tatactctac ccgtaccgca aaccgacaca ggtagtcgag
     3901 gcgagtagcc tcaggtgatc gagagaactc tcgttaagga actcggcaaa atggccccgt
     3961 aacttcggga gaaggggcgc tgactgaagg tcagccgcag tgaataggcc caagcaactg
     4021 tttatcaaaa acacagctct ctgctaaatc gtaagatgat gtataggggg tgacgcctgc
     4081 ccggtgctgg aaggttaaga ggagtgctta gcgcaagcga aggtatgaat tgaagcccca
     4141 gtaaacggcg gccgtaacta taacggtcct aaggtagcga aattccttgt cgggtaagtt
     4201 ccgacccgca cgaaaggcgt aatgatttgg gcactgtctc aacgagagac tcggtgaaat
     4261 tttagtacct gtgaagatgc aggttacccg cgacaggacg gaaagacccc atggagcttt
     4321 actgcagttt gatattgagt atctgtacca catgtacagg ataggtagga gccatagaag
     4381 tcgggacgcc agtttcgatg gaggcgatgt tgggatacta cccttgtgtt atggctactc
     4441 taacccggat aggtgatccc tatcggagac agtgtctgac gggcagtttg actggggcgg
     4501 tcgcctccta aaatgtaacg gaggcgccca aaggttccct cagattggtt ggaaatcaat
     4561 cgcagagtgt aaaggtataa gggagcttga ctgcgagagc aacacctcga gcagggacga
     4621 aagtcgggct tagtgatccg gtggtaccgt atggaagggc catcgctcaa cggataaaag
     4681 ctaccctggg gataacaggc ttatctcccc caagagttca catcgacggg gaggtttggc
     4741 acctcgatgt cggctcgtcg catcctgggg ctgtagtcgg tcccaagggt tgggctgttc
     4801 gcccattaaa gcggcacgcg agctgggttc agaacgtcgt gagacagttc ggtccctatc
     4861 cgtcgcgggc gtaggaaatt tgagaggatc tgctcctagt acgagaggac cagagtggac
     4921 ttaccgctgg tgtaccagtt gtctcgccag aggcatagct gggtagctat gtagggaagg
     4981 gataagcgct gaaagcatct aagtgcgaag ccctcctcaa gatgagattt cccataacgt
     5041 taagttagta agagccctga gagatgatca ggtagatagg ttaggagtgg acgtgtggtg
     5101 acacatggag cggactaata ctaatagctc gaggacttat ccaaaagatg aaaccagtcg
     5161 ctattgacag cttaaggaat tcttgttaga ctatagttat tcaattttga gtggagaaga
     5221 ctcgtaagtt aagtgacgat agcctaggag atacacctgt acccatgccg aacacagtag
     5281 ttaagcccta gaacgcctga agtagttggg ggttgccccc tgtgagatac g
//
LOCUS       DARYLD010000086         5187 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYLD010000086 DARYLD010000000
VERSION     DARYLD010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5187
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..544
                     /locus_tag="TU651_001830"
     CDS             <1..544
                     /locus_tag="TU651_001830"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylglucosamine-1-phosphate
                     uridyltransferase"
                     /protein_id="HEL0897789.1"
                     /translation="KQLYIKTGASSIVNGQDLYNAIEQYGTIGRGKSGNFATSMAEDI
                     ALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSFDQIGEVRTVTGKTP
                     GSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSMESTGIYTLNNPTIV
                     LKDGTKKIVEGQFIIRKLGN"
     gene            546..1052
                     /locus_tag="TU651_001831"
     CDS             546..1052
                     /locus_tag="TU651_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897790.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            1196..1618
                     /locus_tag="TU651_001832"
                     /pseudo
     CDS             1196..1618
                     /locus_tag="TU651_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2147..2872
                     /locus_tag="TU651_001833"
     CDS             2147..2872
                     /locus_tag="TU651_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL0897791.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            2862..4373
                     /locus_tag="TU651_001834"
     CDS             2862..4373
                     /locus_tag="TU651_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL0897792.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            4375..4890
                     /locus_tag="TU651_001835"
     CDS             4375..4890
                     /locus_tag="TU651_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL0897793.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
BASE COUNT         1501 a          871 c         1223 g         1592 t
ORIGIN      
        1 aaaacagctt tatattaaga caggtgcatc atcaattgtg aatggtcaag atttgtataa
       61 tgcaattgag caatatggta ccattggaag aggtaaatcg ggaaattttg caacaagtat
      121 ggctgaagat atagcattac tttatgatag tagtggtaat ttagtttctt ccggtatgat
      181 agaggctatc aaaggggtag atgaaggtaa gtatttgtct ggtgcatttc agtatgaata
      241 tagtcctcag tttgttaaat cttttgatca aatcggtgaa gtgagaacag ttactggtaa
      301 aactccaggt tcttcacttt taaatattcc aggggctaaa acttgggcag gtaaaaatat
      361 ggctttgtca cagtctgaat taatgatgcc atctattgat actagtaact taaaattgga
      421 ggatgtatta ttaagtatgg aatcaacagg aatttatacc ttgaataatc ctacaatcgt
      481 tttgaaagat ggcactaaaa agattgttga aggacaattt ataattagaa aattaggtaa
      541 ttaatatgac acaaacattt tttaacaatg acgttgatga aagacgtcga caactttact
      601 tagatgctcg ttcaaaggga cacttagaga agtgctttag aggggattct gggtttaaaa
      661 taaatgctaa agactcatat tttcaatcga tcacagatat aaatgtgctt attgagcgct
      721 gcttgtatcc cttgtatgat ttaggagata gcattatccc acatgaaact gaaagaatac
      781 tgtctcaatt ctcaacttca aaaaatgttg tagaattata tcaagttgtg tcatatattt
      841 tctatcaaaa gaacaacaaa ctactaaaga agaacttttc cttttatatt gattttaatc
      901 ctatgatccc tgatttagtt ttttctgtta aaaggttatc tcctgaaaat atcgtgactg
      961 atgatgaaaa agcgatggtt ggttttataa aaaacatgtt tcaaaaaatt cctcaggtac
     1021 agtcttatct tgaagctcaa aattgcaaat agtttagatg aatacttgaa aaatggattt
     1081 gaaatagctt aaataaaaat agagtatgct tttcaatcag acgaggtaag ggtattattg
     1141 gaaaaagatt gagcagtatt tatcgattaa gctataaaaa cgaaagataa cacacatggc
     1201 acgcagtcaa ttaacatggg aagatgttag tcaatatgag gaaatcaagg gttatggcca
     1261 acaggtttgg aagcatcagg gagaatatta tctagtcaga gaagaaggag gaattgctgt
     1321 acaacgagta gtgtataaac tccctaatga gcttttccaa ttactggaaa gtgaccgaaa
     1381 atttttatta gaaatagatt tttatgtcaa aaataactgc tggctgccaa cagaagagga
     1441 gaaaatagct agtgataaag catttctaca aagatcccca atagcattaa ttgcagatcc
     1501 aaccagttgg gaactgttta cctaagaaga gctaagaaaa ctaattccaa ttgcggagca
     1561 aaaatggata gattggaagg gaaaactgcc agatgattat gtcagtcctt tgaaataatg
     1621 tttaagatag cggatctgag ggcagctatg ttaggggccg ttgttagctg tattaggtag
     1681 gtgaaaagtg gttatttttg ggtacaatca aaagttctat atataaccct tgcggtggag
     1741 ttacccacta cgggtattgt agagcttgaa aagctgggtg cgagagagga ctggactggt
     1801 tctctctttt ttgtctcttt gtcaagctta tcaagcaata ataggaccta aggtagttct
     1861 tgttgagaca tattgccgta tttggcctta gctggctggc aaaaaggctt ttatggtaag
     1921 aaggtatgtc ttgtaaggtt ttgctgttgt tgtatcaatt agtaaatagc tcaataggct
     1981 agctctttgc catacttaag gctattgaat atactttcag aaaacaagga tttttctctg
     2041 aaaatgaaag tacttcctaa aagtgggctg tctattgaaa gtgttttaat atctgctaca
     2101 ataaagatgt gaacgttctc taaaattaat aaaaggagta gaaagcatgc ttgaaaaacc
     2161 aagcaaggca gagctactga cagctctgaa agacgggctg atcgtttcct gtcaagctct
     2221 gccgggcgag cctctctatt cagaggcagg aggtatcatg cctctgatgg caaaggcagc
     2281 agaggaagca ggagcagtag ggataagagc taatggggtt cgagatatta aggaaatcca
     2341 agcggtgacg gatctgccaa tcatagggat catcaaaaag gagtatcctc cgcaagcgcc
     2401 ctttatcacg ccaaccatgg cagaggtaga cgccttagcg gccttagatg tagcggtgat
     2461 agccttggat tgtacgcaaa gggagcgtca tgatggctta gcgatagcgg actttattcg
     2521 atcgataagg aagaagtacc cagagcagct gtttatggca gacatcagta cgcttgaaga
     2581 gggtctagta gcctatgagg ctggtataga ttttgtaggg acgaccttat cagggtatac
     2641 gccttatagt cgtcagggga caggtccgga tatggagctg ataagtgcct tgtgtgatgc
     2701 aggggtatca gtgatagctg agggcaagat tcatagtcca gaggaggcca gggctgttca
     2761 ggctttggga gtagctggta ttgtggttgg tggtgctatt accagaccaa aggaaattgc
     2821 agagcgcttt gtggcggctc tcaagaagga ggagaaatca catggatttt aagaaatttt
     2881 caaaattggg tcaagccttt atgctgccga tctcaatctt accagttgct ggtttgttgt
     2941 tggggattgg tggggccctg tcaaatagca atgccattgc acaatttccg atattaaatc
     3001 aagcatggct acaggctatt tttaccatta tgagcacagc aggtaacgct gtttttgcta
     3061 atattgcctt gatttttgcg attggtgttg ctgttggctt agccaacgga gataaaggaa
     3121 cagccggtct ttcaggtgct gtggcttatt tggtctttac ggcaaccatt agcggctatc
     3181 tgactctttt ttcagcaaag gacgctcaga ttgatacggg tgttttaggg gctttgacgg
     3241 ttggcttagt tgttgttagc cttcacaata agtaccgaaa gatcgaactg ccagcctttt
     3301 taggcttctt tggcggctct cgttttattc cgattgtttc ctcattggca gcgattgtga
     3361 ttggtagtgt tttctatgtc atttggccac ctattcaaaa tctcctagta gtgtttggtg
     3421 aaaaaattgc ggatatgggg agcatcggaa cattcttgta cggtttcttt ttacgtctga
     3481 caggagcagt agggctgcac cacaccattt acccaatgtt ttggtataca tcacttggcg
     3541 gtagtgaggt tgtagcaggt gagactatcc aaggagcaca aaatatcttc tttgcgcaat
     3601 tggctgatgc taaccatacc gacttgttta cttacgggac acgctttttt gcaggacgtt
     3661 ttgcaaccat gatgtttgga ctacctgctg cctgtcttgc tatgtatcac gctattccaa
     3721 aggctaatcg taaaaaggtt ggtagctttt attcaagtag tgccttgact tccttactaa
     3781 cagggatcac agagcctatt gaatttgcct ttttatttgt agccccttgg ctctatgtag
     3841 ttcatgcttt cttagatggt tgttctttct tagttgctga tttattaaag attcgtatcg
     3901 gtaattcctt ctcaggtggt ttgattgact ttttaatctt tggtgtgttc caaggaaatg
     3961 atcataccaa ctggctactt gttatccctg ttggtatcgt gtggtttatg gtttattact
     4021 ttgtctttaa attctttgtg agcaaattcc aggttgctgt accgggaatg gtagctcagg
     4081 tagaagcaga aggacaagca gagactacta atactcaaag ctcatcactt cgtgaggtgt
     4141 cattagctat tattgaggct ttgggaggac aagctaacat cgaagatgta accgcttgcg
     4201 cgactcgctt gagagtgtct ctgtcagata gcagcttggt taacaagaat gttttaacct
     4261 cactgggagc aacagctgta ttagatgtta aaaatggcat tcaggctatt tatggtggta
     4321 aggctatctt gtatagtcaa gaaatcaatc aactattagg tagagaagat taacatgata
     4381 aagaagtgga agcaattatt atcagcaaaa aaagctgatg cgttaagcga tcgtatttta
     4441 tcagtggcta agggacaatt agttcctatt accagtgtca gtgatcctgt cttttcagaa
     4501 aggctaatgg gcgatggctt tgctattatt cctcaggagg gcgctattta tgcacccgta
     4561 acaggaaggg tcatgacggt ttttccgacc aagcatgctt atggcatcgt tactccagct
     4621 ggtcttgagg tcttgattca tatcggtgtt gatactgttg agctgggaga agctgccttt
     4681 agctctgata ttgttgctgg tcaggaggta gtagctgggc agttattggc tcaggtctct
     4741 ttgccagtgc ttgaagctgc tcaaaaagac agcaccgtta tggttgtctt tacaaactca
     4801 caggacattg ctgatatgcg tcttgctgat gctggagcag ttgctgctag ggcagaagtc
     4861 ggccaagtta ggctaaaggc tactctctag ctagaggcta tcgatccagt ccttgatgac
     4921 aactaaaagg tcatatgaaa aaactgcacc ccagcacttg gctaagtcgg tcaatgcctt
     4981 ggggtgcttt tattattgtc agcaatcagc aggctttgat tgtcctatct tttaacctct
     5041 atttaaatgt taacagctgt cgtatgtgcc ttgtggcaaa taaaagaaaa gctcagcgac
     5101 ctgtttctca tattgcttag cacattttat tttagggggg ctattatatc ctccccagta
     5161 tacaagggct gaaaaaggaa aatagag
//
LOCUS       DARYLD010000087         5055 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYLD010000087 DARYLD010000000
VERSION     DARYLD010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5055
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU651_001836"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TU651_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL0897794.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1245)
                     /locus_tag="TU651_001837"
     CDS             complement(664..1245)
                     /locus_tag="TU651_001837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL0897795.1"
                     /translation="MCDACQRHFCRITQPTCSNCYQYRHEGACQDCIAWKRQGYQVDH
                     QSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKAYTLVPVPVSKQRYDE
                     RGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNRYRLKKGAALPPKILL
                     IDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TU651_001838"
     CDS             complement(1473..1658)
                     /locus_tag="TU651_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL0897796.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU651_001839"
     CDS             complement(1780..2568)
                     /gene="spel"
                     /locus_tag="TU651_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL0897797.1"
                     /translation="MRIFLRQNCRLVNMSTTFFIVVLSLVVFSVRMVSAEGTINIKDI
                     YSPRWDVDKTLSPTTLREIYNRDTIKKENKPVTGKRGTQVIIDAQHKTKVWEFDDYNF
                     IISSNLYPSVEGKFNVGDNVDVFGLALSAEVFSKDQIHSINGGLVKVNERKGAGKTIY
                     MNVFIDGHKKDETSKYKITFEKSPVTFQEVDVRLRKSFMLNDEIKLYQYGSKVLSGNW
                     EFHGSGENEEGADLFKYPDYRYNNLIDIDKKSHIDVYLFTNKEN"
     gene            complement(2835..3614)
                     /gene="spek"
                     /locus_tag="TU651_001840"
     CDS             complement(2835..3614)
                     /gene="spek"
                     /locus_tag="TU651_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL0897798.1"
                     /translation="MKKNTLALLFLVCVSLTLCTTESVFSDTYNTNDVRNPRNIYAPR
                     YDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKKVISS
                     NLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFNYIDGGIIKTSDVKPEEKAIYINIF
                     GEKELRTLTAKDKITFKNNIVTLQEIDVRLRKSLMGDSKIKLYEYDSLYKKGFWDIHY
                     KDGGIRHTNLFTYPDYTDNETIDMSKVSHFDVYLNEEFSKN"
     gene            complement(3739..4968)
                     /locus_tag="TU651_001841"
     CDS             complement(3739..4968)
                     /locus_tag="TU651_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0897799.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGETDYKKACHAIKAAGYATASDYAELLIQLIEQNDLQKWDAEALAKRKESQMISS
                     QCREVIEFYINLANAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASA
                     QGWEVHRMPTDANPRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNAD
                     ALYVGGPARFNTRDFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETSKSGTFTLDA
                     AEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYANGYYWISYVGGSGKRNYMAIGPTDK
                     DGNIISLWGKLGGKDPR"
BASE COUNT         1483 a         1081 c          801 g         1690 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctgagcatc tataataact tgcgtccctc tttttccagt
     2341 aacgggttta ttctcttttt ttatagtatc tctattataa atttctctta aggtagtagg
     2401 ggataatgtt ttatctacat cccaccttgg agagtatata tccttaatat taatagtccc
     2461 ctccgcagaa accatcctaa cagaaaatac caccaatgac aatactacta taaaaaaagt
     2521 agttgacata ttaaccaaac gacaattctg acgtaaaaaa attctcattt atcttattat
     2581 tctccttaat aaatcaatat agctgtgaaa ctatgttttt tgaacttgaa cctcaaaatg
     2641 cttaaatcgg aagtacttga gcagacttct taaaagataa taaactgatt ctataacgca
     2701 cagaaattaa tctgagcggt tttatcatat tcctcggttg accgatagtg atgcctagaa
     2761 gtctactaaa accgtctaat tcatcaaaat ctatttaaat agactaaaaa ttaaattaaa
     2821 atagcattcg accgttaatt tttagaaaat tcttcgttta agtaaacatc aaagtgacta
     2881 actttactca tatcaatcgt ttcattatct gtatagtcgg ggtaagtaaa taaattggtg
     2941 tgtctaatgc caccgtcttt ataatgaata tcccaaaacc cttttttata caaagaatcg
     3001 tactcataca attttatttt gctgtctccc atcaaacttt tcctaagtct aacatcaatc
     3061 tcctgaagag ttacaatatt atttttaaag gtaatcttat ctttagctgt taatgttcgt
     3121 aattcttttt caccaaaaat attaatataa attgcttttt cttctggttt tacatcactt
     3181 gtttttatta ttcccccatc aatataattg aattgttcct tgcatacaac atgatatgac
     3241 tttactatag caaaaatatt cacatgatca ccaacattaa acattctttc ctgtgaagga
     3301 gaaagattac tagatatgac tttcttaaaa gtgttatcat tccaaactgt agtattttca
     3361 tccgtattaa aaatcaattg cgttccttgt ttggcattta tcgatatatt atttttttca
     3421 ataatttctt tattatatat ttcttttaat cttctattat ctaaaatttc gtctttatca
     3481 tatctaggag catatatgtt ccttggattt ctaacatcat ttgtattgta cgtatctgaa
     3541 aagacactct cagtagtgca tagggtaagc gatacacaca caaggaatag caaagccaag
     3601 gtattttttt tcattttttc tcctaatatt ttttaaattt aatcaattta cttagcaagt
     3661 atactatatt taaataataa ttcaactata atttaaaaaa aacaaaaaac cgccctcaat
     3721 caagagagcg gttttgtctt atctcggatc tttacctcct aatttacccc aaagactgat
     3781 aatattcccg tctttgtcag taggaccaat tgccatataa ttacgcttac ctgagcctcc
     3841 gacatagcta atccagtagt agccattggc gtaaccctca ctatcaaagc taacggtttg
     3901 gccttgctta taactatcta ctacctcact ggttaaattc ggccagcggc ggacgttgat
     3961 ctctgcggcg tcaagtgtaa aagtacctga ttttgatgtc tctacgatcg tgtctgaggt
     4021 ttgcgggtct gtgctgaccg tttgtgcagc aacatctccc tgataaggag gataaaacca
     4081 gccggccaca ttagtaaagt cacgagtatt aaaacgggcc ggacccccta catacaacgc
     4141 atctgcatta ccatcaatat tttgctcgat agtctgcata gtgtaaccat ctgagtcaac
     4201 gtacacaaga cccgtatgac cataattgat accaccaaac caagcgtcca tgacaaaaaa
     4261 tgccccagct cgtggatttg catctgtagg catgcgatgg acttcccagc cctgcgcact
     4321 tgcgctatct agtaagtccg ctgcgttgcc ccagagatcg acaccaaacc agtgcttagc
     4381 tgcgtaacaa gggacatctg cacattgcgt gccataagcc ccgtccttat caacacccat
     4441 accagcatta gccaaattga tgtaaaactc gataacctct cgacactgcg aactaatcat
     4501 ttgtgactcc tttctttttg ctagggcttc cgcgtcccat ttttgtaggt cgttttgctc
     4561 tattagttgg ataagcagct ctgcataatc acttgcagtg gcataaccag ctgcttttat
     4621 tgcatgacaa gcctttttat agtcggtctc cccgataact gatttgtatc gtggattatc
     4681 cactaaaaac tggccatgat caaggattga ctcgtcccaa ctgtcatagg ctctaaagcg
     4741 gtccacgaga tccgtcacga cacctggctg atactcctct tgtgtcttgg tatcaaaaga
     4801 tttaccagac catgagctat ctgccttgat accaaacaat gcgttatgtg gggcatactt
     4861 gccccaaccg ctctctaaaa tagcttgagc agccgtcaga gatggcaaaa tcttatgatt
     4921 gtgccactct gcgataactg cgctttttat gtcgtctaaa aaggtcatct gtcctcctca
     4981 cctaaaaacg gataaaagat aagagcaatc acagatagcg gtaaatatag tattgcgatt
     5041 gctaggacta ttgct
//
LOCUS       DARYLD010000088         5021 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYLD010000088 DARYLD010000000
VERSION     DARYLD010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5021
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..693
                     /locus_tag="TU651_001842"
     CDS             <1..693
                     /locus_tag="TU651_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897800.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TU651_001843"
     CDS             complement(1204..2832)
                     /locus_tag="TU651_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897801.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TU651_001844"
     CDS             complement(2837..3568)
                     /locus_tag="TU651_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897802.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TU651_001845"
     CDS             complement(3605..3862)
                     /locus_tag="TU651_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL0897803.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4234..>5021
                     /locus_tag="TU651_001846"
     CDS             4234..>5021
                     /locus_tag="TU651_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL0897804.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQG"
BASE COUNT         1625 a         1105 c         1026 g         1265 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaaacgaaac tacggagaca aactaatcag
     4141 cagctatttc ttacatttag ctagcgtgtt aagatagcta ttggaaaaga tttttaggaa
     4201 tacttcatat ttctatcatc aaaggagaga gaaatgataa ataaaagaaa gaaaaaactt
     4261 atctacaggt atggtgtctg ctcggcagca gttatcctag cagcgcttgc tagcctagga
     4321 acatgtaaag aagcaaaagc attatctggt ccgccaggat acccacttac tcgtgatttc
     4381 tcccgtaact tcctagaaga aaatactgca aaatatttag atcaattaag agaacatcta
     4441 cagcacagat ttagtgaact tgagagctta acaagaaaat tagagaaaga aggcggtacc
     4501 cgaggtccag cagggcctcc ggggccagcc ggacctaaag gggaacgtgg cgaaccaggg
     4561 cctgttggac ctatgggacc tagaggtgaa caaggtccta aaggcttaga cggagcacgt
     4621 gggcccgagg gacagcaagg aaaacctgga cctgtcggac ctcaagggcc ggcaggtcca
     4681 gcggggcaaa aaggggaaac cggacctcag ggacctcgtg gagataaggg cgatactgga
     4741 gaaactggaa agcaaggacc agcaggagaa cgtgggccag ctggacctca gggaccgcgc
     4801 ggagacaagg gtgaaaacgg tgcacccggt gagcaaggcc ctattggtcc aaaaggtgag
     4861 actggaccta aaggtgacaa gggagaacgc ggcgaaaagg gcgaccaagg tcaacgtggt
     4921 gaaaagggcg accaaggtca acgtggtgaa aagggcgacc aaggtcaacg cggtgaaaaa
     4981 ggcgagcaag gccaacgtgg tgaaaagggc gagcaaggcc a
//
LOCUS       DARYLD010000089         4806 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYLD010000089 DARYLD010000000
VERSION     DARYLD010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4806
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            125..1708
                     /locus_tag="TU651_001847"
     CDS             125..1708
                     /locus_tag="TU651_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL0897805.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
     gene            1723..>4806
                     /locus_tag="TU651_001848"
     CDS             1723..>4806
                     /locus_tag="TU651_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL0897806.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFTNILLVEHEAVD
                     DSNFLDNLKRINKTFLENVSHSEYNGVQVQRDISKKQGTSVYIAPVVFACNIDYPLET
                     EFSRKNLGKVSYMISQTPGVWLDFQTYIVDGDLILCWDSVDELFPTGMLEDMMDSLYE
                     LIISLTQKEEWEKKVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRV
                     AIIDSETKEEITYHKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFT
                     GAAYVSIGIAQPNDRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVA
                     KLKQPVEISPYDSAYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMV
                     SAIDFDLSVYDIFGILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMI
                     VTMAEGKNRNLPFRIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHL
                     NVPRKIPKDWISIPYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEE
                     LTNKKYFEQDGMRWYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVF
                     ENIKKAIALIVKDGNVNKLVGFAEIFDCKESNQMLLNSDFEKETEEYKKQKDEYIN"
BASE COUNT         1799 a          527 c         1022 g         1458 t
ORIGIN      
        1 aagttattta tatcgacaat cagagaataa aaattgaaga taaggtaaaa aggagtaata
       61 aagatttgat agcattcagc atttcatcga aatattttgg agcaatttgc atataggagg
      121 aagtatgaat atagaattga aagaaaattt agaaaaaaat tatgatgaca atgtttggga
      181 acatgtgacc ttgggagagt ttgttgcgaa ctgtgcggaa acgtataaag ataaaacagc
      241 gattgtagat ggagaattaa acttatctta tgatgagctt gataaacttt cgaataagta
      301 tgctaatgga ctacttaaag caggttttaa aaaaggagat aagattgtat tacagcttcc
      361 aaattgttat gaatttatag tgatatcttt tgcaatgttt aaaacaggaa ttattccgat
      421 tatgagtttg cctgcacatc gaaagaatga attaaagggt attatagaaa agtctgaggc
      481 ggtagcatat atttcaaagg ataaatattt aggtttttca tatgtggata tggttcggga
      541 tatgaaatct gaattaaata cgaacttgga gatttatatt cttggagaaa gtgaagaata
      601 taaaaatttt tcgtcactta ttgagaatga ttgtttctat aaatatccgg atgtcgatta
      661 caggagcata ggattattgt tattatctgg cggtacaaca ggaataccga aactgattcc
      721 aagaagacat tgcgattata tctatgttgc aaagaaaacg acggaccggt gtaacgtaaa
      781 tcaggaaagt gtatatcttg cttctttgcc aatagctcat aattttcctt tggggtgtcc
      841 agggataatg ggtacttttg caaaaggcgg aaaggtggtt ttgtgcaatg tgacaagccc
      901 tgatgaaatt ttacctttaa ttgaggaaga aaaggttacg ataacaggat ttgttcctgc
      961 aattgccaat atttgtatgg attatttaga gtatgaagag tatgatcttt cctctttgga
     1021 ggttatacaa gtcggaggtt cagttttgga accttggttg gcagaaaaaa ttgaaaaagt
     1081 ttttgatgtt aaactacaac agattttcgg aatcgctgaa ggattgatct tgacaacaaa
     1141 tgaagaagat aacgataaaa taagatggca aacacaaggc aaaccaatca gtgaacatga
     1201 tgaaatactg attgtggatg aacaaggaaa aattgtaggg attgaagaat atggagaact
     1261 tatcgttaga ggtccttata ccatttatgg ttattataat cttcctgaag taaatgaaac
     1321 atgtataaca caagattgtt attttaagac tggtgataaa gcacgaaaac taaaagatgg
     1381 taattatcaa attgtcggaa ggatcaaaga aatcatcaat agagcaggtg aaaagataac
     1441 accacttgaa ttagaagaaa ttttgcttac tcatgaaaat atcaactcgg tacaagttgt
     1501 agggctgcca gatcgtctgc aaggagaatc cattgctgta tttattttaa atggagataa
     1561 ggagcttaca ctggaagaag ttagaaaatt cttgatttct aataatgtgg cggattttaa
     1621 attgccggat actgttaaat atattgatgc gtggccatta acagctttag ggaaaataga
     1681 tagaaataaa ttaaaagaaa ctttttaaag gaggattttg gaatggaact taacaatata
     1741 aaagaaagag ctaaagaatt agtaaaggat tggttgaaaa gtatatttgt agagaaagta
     1801 gtttcagaaa atgaaaattt aattgaaaaa ggtttaagtt ccattcaagt catgcaactg
     1861 tctggaaaat taaagaaaac ggggataaaa atttcgtttg caaaacttat ggaagaaccg
     1921 aatttgtcca agtggtatga acttattgat aaatccagag tgaaaagtga taagaatata
     1981 gagtcatcaa ttatccaaag tgatgaaagt aagtttgatt taacagatgt ccagtactcc
     2041 tatttaatcg gaagagaaga tgatcagatt ttaggtggcg tgggttgcca tgcatatctt
     2101 gaaatagatg gagaaaatat tgatgaggat aagttaaaag aggcttggaa taagcttcaa
     2161 tacagacatc ccatgcttag aacaaaattt acgaaagacg ggaagcagga aatattatac
     2221 aaaccgtaca gtgaagaaat agaagttttt gatttatctg atcttgatga agaaacgctg
     2281 catctaaaat tagtagaaat tagagaacaa aaatctcata ggaaattaaa tgtaaatcaa
     2341 ggtcaggttg caggagtagc actagcaaaa ttttcagatg agaagtcaag gatatttttt
     2401 gacgtagatt tgcttgtatc cgatgtaatg agcatgagta ttatgattaa agaattagct
     2461 gaactttatt caggagtaga acttgataat ttgaatgagt atacgtttaa ggattatatg
     2521 caaaacggaa ttggcgaatc aatcaatgat gcagataagg agttttggga acaaaaaata
     2581 aattcctttg aaatagaaag accgaattta ccattaagga aacagccgga acaaattaaa
     2641 gaaacgaagt ttacaagaag aaagagaatt attaaaaaaa gtgaatggga aaccataaaa
     2701 gatatagcag catcgtatcg aagtacacca tctatggttc ttctaactgc ctatgctctt
     2761 gttcttgaaa gatggtgtaa tcaggataaa ttttttatca atataccgct atttaataga
     2821 gatttagaaa atgaaaatct aaaagaaatg gttgctgatt ttacaaatat tttattggta
     2881 gagcatgagg ctgtagatga ttcaaatttt ttagataatt taaagagaat aaataagaca
     2941 ttcttggaaa atgtatctca cagtgagtat aacggagtgc aggttcaaag agatatatca
     3001 aaaaaacaag gtacaagtgt gtatatagca cctgtggttt ttgcgtgtaa tatagattat
     3061 ccattggaaa ctgaattttc aagaaaaaat ttagggaaag tatcttatat gatttctcaa
     3121 acaccaggag tttggcttga ttttcaaaca tatattgtag atggagattt aattctttgc
     3181 tgggatagcg tggatgaact ttttccaaca ggaatgttag aagacatgat ggattcttta
     3241 tatgaattga tcatatcttt aacacagaag gaagaatggg aaaagaaagt agatgtttta
     3301 cctgaaaagc aaaagtctat tagaatgcag gatgttgagg gaattttacc acttcaatat
     3361 cctagcgaaa cgttatatga cggatttctc agaaatgtaa aactcaatcc agatagagtt
     3421 gcgattatag attctgaaac gaaggaagag ataacatatc ataaacttta tgaaatctct
     3481 ttaaaagttg cggattgttt aggtaaaaat ggtgttaaaa agggagatta tgtaggaata
     3541 acacttccaa gaggtagcag acaactttat gctatttttg ggattttatt taccggtgca
     3601 gcatatgtat caattggtat tgctcagcca aatgatagaa gaactaaaat ttatgatcaa
     3661 atcggaataa agtgcattat aagtgatgaa aagacagtga tagattgtaa attaaataaa
     3721 aatgaagtta aaattattga tttggatgta gctatggcaa atgtggctaa attaaagcaa
     3781 cctgttgaaa ttagccctta tgatagtgcg tatattatta tgacgtctgg aacaacaggt
     3841 gttcctaagg gtgttgagat tatgcataca agtgccgtta atacttgcat tgatttaaat
     3901 gaaaaataca atgtaaatgc tgaagataca atactgatgg tgtcggcaat agactttgat
     3961 ttgtcggttt atgatatttt tggaatactt catgctggag gaacggttat tacaacaagt
     4021 gaagataatt atagaaatcc tgatgaatgg ttaaatttag tcgatgaata taaggttaca
     4081 atatgggatt ctgtgccgat tttgtttgat atgattgtta ctatggctga aggtaaaaat
     4141 agaaacttac cttttagaat tgtgatgctt tcaggggatt ggattgctat aaatttacca
     4201 gaaagattct ataatattag tgaaaatata aattctattg ttgtcgctat gggtggagcc
     4261 acagaagcat ctatttggtc aaaccatttg aatgtaccaa gaaaaatacc gaaagattgg
     4321 atttccattc catatggtag acctttgaaa aatcaagtgt atagagttgt ggatgaattt
     4381 ggtaggatct gccctaatta tgttaaaggt gaacttctta tcggtggagt tggtgttgct
     4441 aaatgttatc atggtgacga agaattaacg aataaaaagt acttcgaaca agatgggatg
     4501 aggtggtata gaactggaga taatggtaga acatggaatg atgggattat tgagtttctt
     4561 ggaagaaaag atactcaggt aaaagttaaa ggacatagaa tagaacttgg agaaatagag
     4621 aatgctttaa ttgtatttga aaatataaaa aaagcgatcg ctttaattgt taaagatgga
     4681 aatgttaata aacttgtagg atttgcggaa atatttgatt gcaaagaaag taatcaaatg
     4741 ttattgaatt cagattttga aaaggagact gaagaatata aaaaacagaa ggatgaatat
     4801 attaat
//
LOCUS       DARYLD010000090         4192 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYLD010000090 DARYLD010000000
VERSION     DARYLD010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4192
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(44..754)
                     /locus_tag="TU651_001849"
     CDS             complement(44..754)
                     /locus_tag="TU651_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL0897807.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
     gene            complement(1201..2559)
                     /locus_tag="TU651_001850"
     CDS             complement(1201..2559)
                     /locus_tag="TU651_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL0897808.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(2967..3197)
                     /locus_tag="TU651_001851"
     CDS             complement(2967..3197)
                     /locus_tag="TU651_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897809.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(3291..3704)
                     /locus_tag="TU651_001852"
     CDS             complement(3291..3704)
                     /locus_tag="TU651_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897810.1"
                     /translation="MARKLAIIVIATGILFALIACILFFKKDILQVFPRMDIAWVGFL
                     VVAILLCVSGIWVFSISGKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLV
                     FMGYLNKVSGFSIIGVVLISGIVSWIYHLYLRKVE"
     gene            complement(3739..3936)
                     /locus_tag="TU651_001853"
     CDS             complement(3739..3936)
                     /locus_tag="TU651_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0897811.1"
                     /translation="MKNRLEEIRKENGITQEELASILEVSRQTIGSLENGRYNPSIIL
                     AFKIAKYFSLSIEDIFIYEEE"
BASE COUNT         1315 a          808 c          562 g         1507 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata tttaatattt tcttataact attgatgtta aataaatgaa aatatatcat
     1141 tcttgtttac taccaacttc taactagtat agtacgagga tataattaaa tcttcgtctt
     1201 ttacaacatt ttccaatata acgctagtgg taacaacaat aataatccaa tagctgatac
     1261 aatcgaacaa tatattgtca ttcttgcttt tgataaattt tcattttgta aaaccaccat
     1321 caagggtggt gcctgaaatg ggaaaaatac acttgaaaaa cctataactt caatatgaca
     1381 taaaaatgtt tttgaaacat tactaacgcc tgaaatatta tcaatcaaag gtgtaactac
     1441 tgccggaaca cccggtaaag ttactataaa tcctaatata atacacaata caacgaaaaa
     1501 agttaaaaca ttaaatgcac ttgctgtttc caaagaaaca atattgatta aatgcacagc
     1561 aatgacattt gcaagtcctg aagattttgc tatattccct aaacttatga ttccagctac
     1621 ataaaaaaat ggctcaaaat ttatttttct taaaggttgc ttttccataa aatttgaatt
     1681 tggtaacatt acaatcaagg cagttgccat tcctgtccaa ccggttggta ctttatgaat
     1741 atgttctgtc atccagaaag acagagttat aaataacaaa actattaaca atttctgctc
     1801 ttttgttatg tcaatggctt ttttggacac gcaaatcgaa tctttacatc ttctataaaa
     1861 taaccgcatt gtaaaatata aaatcaatat ttttccaact cctaaaatag ggaagtacaa
     1921 gagaaagtat ctgctatagg atatatttat ggagtaaaga cttaaaattg ctccagtaaa
     1981 aacattattt ggaacattgg aaggtaatac ataaaatgca ggtatatagg ttgctaaaac
     2041 ccctgacata acaattcctt cccattcctt acttcctttt tcataaccta attctaaaga
     2101 tagggcattt agaataggta aaagcaaaac tactctaccc attgctgatg gcatcaaaaa
     2161 aattagtacc actcctagca aaatcgtccc aaataacact ttagaatatt tccccatgca
     2221 caccggaata aaaaatctcg caagtaatct atcaagttca gtatgcttta ctgccgcccc
     2281 tataataaca cctgaaataa caagccatgc tgcacctgaa gttatccctg ataagatgac
     2341 ttgcttctca gctatattcc ctatcataca agctgtcata aataaaatgc ttgtatacca
     2401 tgcaggaatt atattgcttg ccaaaaggaa gatagatata agaatcaaaa taaaaacttt
     2461 ctctatattt gaaataaatg gtagtacaga tacaaacaac ggtaacattg taaatatcca
     2521 ctttatatga ttattcctaa ttccagattt taaaatcatc ctccattttt gacctccaac
     2581 tctaatttat ttcatagtat tataccatat ttattttcat tttataggtc tacctcttgc
     2641 ttctttgtct gtgttaatcg cttttcttgt ttttataact gctctataca agtcttaact
     2701 ttttctgcct gtttaatttt ttctcgtatc tctaatattt tattgtgtaa gctctttttt
     2761 tctttcttca tattggcgac ttccgatttt catttgctaa tgactaaggt cttgctttcg
     2821 cccaaatgct cttttagata tttcttggca ctctcaaata aaataatctc tgctgtatca
     2881 acgttagctg atatgccctc tgcaagagcc ttcggagaac gcacgcacct gttgaggtgt
     2941 atatgtacac tcttgtaaac aagggactat tcctctgtgt ccgttgcttc ctcttgcact
     3001 tctatgtttt cttctgtttg ttctcttttc tctatgattt ttaggatttt ttgattgact
     3061 gctccctttt cataaaggcg tctatctctc ttttttctct cttcctgttt cgactgaatg
     3121 atgggctttt ttcttttgtt ttgtaactgc ttgatttctc catctgtcat taaaattttt
     3181 tcatctatgt ttttcatttt ctattttcct ctctttctgt tttgagcaac aaaaaaacag
     3241 taaaccattt ttttgattta ctgttttcta ataaatatta tcttagttat ctattctact
     3301 tttcgtaaat ataaatgata aatccatgat acgataccac ttatcaaaac aactccaatt
     3361 atagaaaacc cagaaacttt gtttaaatag cccataaaaa ctagaagaaa aaaaactatt
     3421 cccagtaaag ttgtttgaat cacatatcct accatattag ccttagctgt tattaaggac
     3481 tctctttcat cggtttcatt tatccaatct tgttttttac ctgaaattga aaatacccat
     3541 attccactaa cacacagaag aatagcaaca acgagaaagc ctacccatgc aatatccatt
     3601 cttggaaata cctgtaaaat atctttttta aaaaataata tgcaagcaat caaggcaaaa
     3661 agtattccag tagcaataac tataatagct aactttcttg ccataaccat ctcttttttt
     3721 atatttcttt tcattttttt attcctcctc gtatataaag atatcttcaa tgcttaaact
     3781 aaaatactta gcaattttaa aagctaaaat aatggaagga ttataccttc cgttttctaa
     3841 agaaccaatt gtctgccttg atacttcaag aatagatgct aactcttcct gtgttattcc
     3901 attttctttt ctgatttcct caagtctatt tttcacattt aatgacctcc tgcaacaatg
     3961 acaagctaac tttacatata gtataatgtt ttttagagaa aatggcaagt atactttcca
     4021 taaaatcgtt tccttatagg tctagccctt acttttttac atgtacgact cctctatatc
     4081 tgcattttcc tcttatactt ctgtctgttg atgagcactt gcttctcttt gtgatgatat
     4141 ctttactatg cttttcattt ttgggatttt tatcttaatt ttgagtagtc at
//
LOCUS       DARYLD010000091         4067 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYLD010000091 DARYLD010000000
VERSION     DARYLD010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            295..2097
                     /locus_tag="TU651_001854"
     CDS             295..2097
                     /locus_tag="TU651_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL0897812.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TU651_001855"
     CDS             2075..2674
                     /locus_tag="TU651_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL0897813.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TU651_001856"
     CDS             2782..3708
                     /locus_tag="TU651_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL0897814.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..>4067
                     /locus_tag="TU651_001857"
     CDS             3701..>4067
                     /locus_tag="TU651_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0897815.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILG"
BASE COUNT         1256 a          754 c          786 g         1271 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggac
//
LOCUS       DARYLD010000092         3445 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYLD010000092 DARYLD010000000
VERSION     DARYLD010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..1537
                     /locus_tag="TU651_001858"
     CDS             <1..1537
                     /locus_tag="TU651_001858"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEL0897816.1"
                     /translation="NQLLTEYEYFYLLNALIEAIPYVSNITGTYGAFLKHWDNRALHS
                     LTLAEETIFDNYRPNKAFNENANELVKKIKADIVYIDTPYNARQYASNYHLLENIARH
                     QKPILKGITKIFDWKTLKSDYSTKTKALKAMEDLIANINASHIILSYNTEGIISEEDL
                     TLLLQRYSFNNQIDVKRIPYRKYQSKKKSQNKDLYELLFYIQRKPINNRFKSQTKKKA
                     AIISQKKYIKSPLNYIGGKYRLLNQIIPIFPRHINTFVDMFSGGANVGINVPAKKHIF
                     NDMNYRINDMFRYFQSHDPLEILEQIEHRISEYQLSKTNEQGFLTFRKHYNTHPNPLD
                     LYVLSSYSYNYQFRFNNSMEFNNPFGRNRSHFSENMKSNLLNFVARLHRLDATFSDQF
                     FSDFDISTLSIDDFVYLDPPYLITTGSYNDGNRGFTNWGEKQEIEMYQLIRDLNKKQI
                     KVALSNVLVHKGKHNDLLEQFVQDESLYLTTLNYNYKNASYNTRKEDSIEVLITNYKP
                     NPK"
     gene            complement(1558..3171)
                     /locus_tag="TU651_001859"
                     /pseudo
     CDS             complement(1558..3171)
                     /locus_tag="TU651_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1192 a          674 c          465 g         1114 t
ORIGIN      
        1 caatcaatta ctcacagagt acgaatattt ttacctttta aatgctttga tagaagctat
       61 tccttatgtt agtaatatta ctggaaccta tggcgctttt ctcaagcatt gggacaaccg
      121 agcgttgcat tccttaacat tagcagaaga aactattttt gataattatc gtcctaacaa
      181 agcgtttaat gaaaatgcta atgaattagt caaaaaaata aaagcagata ttgtttacat
      241 tgataccccc tacaatgctc gacaatacgc atcaaattat catttactcg aaaacatcgc
      301 ccgacatcaa aagccaattt taaaagggat tactaaaatt tttgattgga aaactcttaa
      361 aagtgattat tcaacaaaaa caaaggcttt aaaagcaatg gaagatttaa ttgctaatat
      421 taatgctagt catatcattc taagttacaa taccgagggt attatatccg aagaagattt
      481 aacactttta cttcaacgat attcgttcaa taatcaaatt gatgtgaaac ggattcctta
      541 ccgaaaatat caatctaaga aaaaatctca gaacaaagac ttatacgaac ttctttttta
      601 tattcaaaga aagccgataa ataatcgctt caaatcacaa actaaaaaaa aggcagccat
      661 catcagtcaa aaaaagtata taaaaagccc attaaattat atcggtggaa aatatcgact
      721 gctaaatcaa atcattccaa tttttccccg acatatcaat acatttgttg atatgtttag
      781 tgggggggca aacgttggta tcaatgttcc tgctaaaaaa cacatcttta atgatatgaa
      841 ctatcgcatt aatgacatgt ttcgatattt tcaatcacat gacccacttg agatacttga
      901 acaaattgag catcgaattt cagaatatca actcagcaag accaatgaac aaggcttttt
      961 aacattccga aaacattata atactcatcc aaatccacta gacttatacg tactatcgtc
     1021 ttatagctat aactatcaat ttcgctttaa taactcaatg gaattcaata acccattcgg
     1081 cagaaataga agtcatttta gtgaaaatat gaaatccaat ctactcaatt ttgtagctcg
     1141 actacaccgt ttagatgcca ctttctctga tcaatttttc tcagattttg atatttctac
     1201 attatcaata gatgattttg tttatcttga tcccccctac ctcataacga ctggcagcta
     1261 taatgatgga aatcgtggct tcacaaactg gggcgaaaaa caagaaattg aaatgtatca
     1321 attaataaga gaccttaaca agaaacaaat taaggttgca cttagtaatg ttcttgttca
     1381 taaaggaaag cacaatgatt tacttgagca atttgttcaa gatgaaagtc tatatctcac
     1441 cactttaaat tacaattata aaaatgcttc atacaacaca agaaaagaag atagcattga
     1501 agtattgatt accaattata aaccaaatcc aaaataataa aagcatagtt gaattagcta
     1561 tgcttttaca aattcaattt ctttattttg aaaataagat ggtaaatcgg aaatatgcag
     1621 ttgtccttta agaaccaaat ctgctcccaa aagcaattgc tctacattga gggctgctcc
     1681 cttaatttgt gtttcattag aggtataatc aagctgctct tgaaattttc caatgaattt
     1741 acttgacacc cacataaaat aaaactcttc ttgtggaatc gtatctggaa aagcttccca
     1801 ccactttatc ggattacgat tttcatctcg tcgcttatta tcctcaatat accgaatcat
     1861 ttcatcagcc tgattgatag atttagaata accttttcca taagcctttg tatctacaat
     1921 cacaccaaaa cgatcttgat agagtaaacc atctggcttt ctgccaccac ctaaaagctt
     1981 agaatgcaat ctatatacat ttctaaataa ttccattgta acaatttcaa aatctcgatt
     2041 tcgcttacca tcgtaagcaa tatcaagcaa ttcaatatat ttcattggta aattagtctc
     2101 ttttaaaaat tttgccttac gcttttctgc ctgctcatcc tttaattctt gtgtaatttc
     2161 tagttcagga atagaaaaat cgttgatctt atccttcaaa gaaactctat tgctagaaat
     2221 atctatcctc aaaccaaaat aattcaatcc ttgaatatct gataagataa tctccagttc
     2281 atcgtaaaaa cccttagccc ttagtttatc taatagaata gccaaagaat tagtttcttg
     2341 gagaaacttg acgatataag ctctccgagt acgaacatac tcgcgattat tgccatgagt
     2401 tgcaaaaaat tcccacatca caaatttttc aagcttgcta tgcttagaat ccccctgagc
     2461 ttgtcgtaaa gcatgaagac cacgaccatt aattttataa ccttgaaatc catctttttc
     2521 accattagta aaggtacgct taatcgtttg tgaatcaacc aaaccaacat tttttagcca
     2581 attacaaata ccgcgtgcat atttatcact tgttccttct atatcagctt taataagttt
     2641 tttctctgat ttagtggcag atcctaacca atcaaacata atatcttcat tataggaagt
     2701 aaagcctttt tcaccacgaa aaccaagctg ctcacctaaa taatatttag tacaataagt
     2761 accgctatca gccaataaag ataagatttg tgtagctggc gggtatgaca acagtgcctt
     2821 tcttaaaata gcagtttctt cttccgaatt aattattgcc ctagaaaaat gcaacccctt
     2881 cgaagtaatt gaaaacatat ccgtttctct atctaccgac acaaaattca ggctaacagc
     2941 ccatcttaaa aaaccatctg atgtccaatt atccgtccaa gttttacctg tattttttgc
     3001 ctgttgaggt acgatgctga tttgaatcaa agaatctgcc attgcatctg aacgctttcg
     3061 gggagatttg ttattcttat cctttgatgt tccaactaat tctaaatatg aaaatgattg
     3121 aatcccatta atcagtttgt ttctgagtga ttctcgtggt acttcaaaga aatctgtacc
     3181 caaccataag ttcttatttt cataagagct ccttaatctt atacttatta tctttattat
     3241 agcatataat taatccttcc agttagcatt atcacaaagc aacaacattt cttatttaat
     3301 ggggctacta tgtagctatt ttaatacatg tttttacctc acgaaaacac ccccacttgt
     3361 caagtctgta actgtactga cccccaaaag ttggacacga catattagtg aaaggattta
     3421 gttctgtatt gcacagggct aagtc
//
LOCUS       DARYLD010000093         3271 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYLD010000093 DARYLD010000000
VERSION     DARYLD010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3271
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(360..1334)
                     /locus_tag="TU651_001860"
     CDS             complement(360..1334)
                     /locus_tag="TU651_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL0897817.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            complement(1335..1793)
                     /locus_tag="TU651_001861"
                     /pseudo
     CDS             complement(1335..1793)
                     /locus_tag="TU651_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            complement(1993..2691)
                     /locus_tag="TU651_001862"
     CDS             complement(1993..2691)
                     /locus_tag="TU651_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL0897818.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            complement(2684..2920)
                     /locus_tag="TU651_001863"
     CDS             complement(2684..2920)
                     /locus_tag="TU651_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL0897819.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
BASE COUNT          952 a          823 c          619 g          877 t
ORIGIN      
        1 gcataatgac ttcctccgtt tgtacataga tcatctcatt atagcacaaa tggccttaat
       61 ttgcagaaaa aacaagaatg ctgcaatagt ccttagcttc agacaaactc ccttacctac
      121 cttgactcct tttttaaagc agctagctag agctgcctgt catcgctaag tatcaaagat
      181 gtcgtaaaca aagcaagctg caaattagac ccctcactat gaaaaaagca gttaggctcc
      241 gcgattgaaa gactccgagt catcaggaac aagacctgta tctgatagaa caagaagggt
      301 catcacttct taagacagct agcaaaaaag atgacttagc ttgtagccac tagctactct
      361 tagctatcgc tttctagcga agctgctgcc tgctctaaaa cagccatgac tgccttgctg
      421 tgctccaagg cctgctctgc cctttccatg tccttattag agataatatc tgaaaaggca
      481 ataaattcat cgtacatgcg atgagacggg tggttaaagt tgacggtcct tgcttgctca
      541 cctcgaatgg ctagtaaaag ctctggtaca gcattaggag cacctaaaac agaaagaaag
      601 cctttattcc cctgaatcgt agagacaatc tctgcactgc aatccttagc cccaatacaa
      661 acagccttaa atcgctcata atccatcagc aaaacaccag aggtgtcaac ctgccgctcc
      721 atattagcta ggtactgaac cgtttggggc ttgccaaata agccaacgag cagatggata
      781 ttataaatat tcaaatcacg caaggcccct ccaccctttt taggatcaaa ggctggtgca
      841 atctccccac gcttaaaggc atcataacga gaggaatatt gagaataatt gcactccaca
      901 agcttaatct ctcctaactc agtcaagtga tccttaataa attgggtgtt tggcaaatat
      961 tggttggtaa tagcttctaa taatatcagc tgcttagctc ttgcaatgct gcttaaagca
     1021 tcaagctcct tggctgtcat ggtaaatggc ttttcacaaa tgacatgctt accagcctca
     1081 agggcttgct tagccacttc aaaatgcaaa tgatttgggg tggcaacata aaccgtatcc
     1141 acctcttcat tttttaggac ctcggctagc tgacagctgg cctgttgaat gccaaaggcg
     1201 tcagcaagcg cctctgcggt ttcaagacta cgaggcgttg aaacaatcgc cattaagtct
     1261 atgcttttga tctcctttaa aacaggcaaa acctctttga caatcatgcc tgtaccaaca
     1321 agggctaatt tcatttattt ctccttttta gcagcttcag ggtaaaccct ctgaaactcc
     1381 tctaacacaa taaggctatc ctcggtaaag cgtaagccta cctcttcaaa ataaggtctg
     1441 aaaaaggcct catgaagcag ccgccattct tccaagcttt tatcaccctc tccttcctta
     1501 taggcatgct ctgctggcac gtccttgaag ggaacaagac taaccttagt aatctggata
     1561 atacagatcg cctgatccct actatccaaa atcacgtcat agctgccctc tttggaaagc
     1621 ggctcatgat caggctcata tcagtcatag gcagaggctg tagctgtttt agtgccttct
     1681 agcactaatt gcgctaataa atcaggctca gctccaaagg cccaggcctc agctagatca
     1741 ccaacaccag gattgatttg ctggtattga gaccataatt cttctgcagt catgttatca
     1801 cctctattga tcgaatcctc tagacaggta ggctcctgct gtattaagca aacctactag
     1861 gcactaggct tcatggaaaa aacttcatca gctccctctt agcctgtgac aagattgctt
     1921 gatacagcta tcaactgtca ccctctgtac agacaagcca gatcttgcta ggccttatgt
     1981 cgatgtgctg tttcacttta agctccaacc gccatcaatt ttaacaattt ctccctgcat
     2041 ggcgctagct tttccagatg ccaaaaacat ggtcagctcg gctatttctt cagccctaag
     2101 ccaacgaccg ataggagtct catcagccac ccactgggct aagccacctg gctcaaagtc
     2161 tgtggctgtc attgctgttt gcactgcgcc aggggcaatg ccaaaaacct gaatgcctgc
     2221 cttggcataa tcaagcgcta gctgtctggt aaaaccagcc agagcatgct tgctggaggt
     2281 ataggcagct ccgccgccac ctgccatgaa gctagcaata gagcacatat tgatgataat
     2341 acctgattga gctgtcagca tctgtgccaa atagtgacgc gtgatgcgga cagctgcaaa
     2401 gaaattgacc tgaaagagag cctcaaaatc agcctgtgtg gtatcaagca agggcttata
     2461 ggcatcaaga acgcccgcag tatgacacaa cacatcaacc ctaggcacag cctcaaaaag
     2521 ctcagctaaa tcacctgtaa tatctaactg taaaaactga aaatctcctg ataaatcagg
     2581 cttttttgcc ttgtcaaccc cataaacagt aaagccattt ctcaaaaaca ggcgcgcctg
     2641 tgccagtcct atgcccgatg acacaccagt gatcagcacc cgcttagtca tagacctcta
     2701 cccagtcagt agcaagaacg tcgcagggag tcggtgccca catggaaaag ccctcgccag
     2761 ctcctgacac gttaatcaaa aagtaaggcg tcacctcaag tgccacacca ttttgttcaa
     2821 tgctatcaaa cagctgaaca tagttttcag cgcctcccca gcccttacga acgtattttt
     2881 tcttggcctt caagcctggc aaaatctctt caaatgtcat ggttttctcc ttttataggt
     2941 ctacatcata gcatgagctc ttttaatgat cattatacca atttactcag cttttgtaag
     3001 cttaaagatc acgaaagtcg caaacgtaca agtttgcttt gtttttagat aaggattcat
     3061 catcttaact aattatgaca taatctaagt gatatgaaat cctttgtaac ccacaccagc
     3121 tttttataat acactaacct gagtgtcttt aaaactgcgg ctgtaattct tgattaagct
     3181 aatacagcat gtctagccag tatatgaaaa taattggaat tattttcgtt agaatgttag
     3241 actattttag ataaagcgtg ttcaatgaca t
//
LOCUS       DARYLD010000094         3255 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYLD010000094 DARYLD010000000
VERSION     DARYLD010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3255
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..1555)
                     /locus_tag="TU651_001864"
     CDS             complement(<1..1555)
                     /locus_tag="TU651_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL0897820.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSVTFPEAANTYNGA
                     VLVVKDMETLKDIQDSIQSINHTGGRASISAYADLTKADLRSISDDKGIISDGDTVIG
                     HIETKKEYLR"
     gene            complement(1558..2310)
                     /locus_tag="TU651_001865"
     CDS             complement(1558..2310)
                     /locus_tag="TU651_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897821.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2641..3120
                     /locus_tag="TU651_001866"
     CDS             2641..3120
                     /locus_tag="TU651_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL0897822.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT         1036 a          605 c          609 g         1005 t
ORIGIN      
        1 atcggaggta ttccttttta gtttcgatat gacctataac agtatcacca tcactaatga
       61 ttcccttatc atcactaata ctcctaagat cagccttagt taaatcagca taggccgaaa
      121 tgctggccct tccgccagta tgattaatgc tttgaatgct atcttgaatg tcctttagtg
      181 tttccatatc tttgaccaca agaactgcac cattataagt gttagctgcc tctgggaagg
      241 ttactgatgt taaatttttg acattggtat atgatttgcc caaaatatcc agctgtcgta
      301 attgactatc ccctctttgc ttaaagaagg cagtctgatt gtcctttaat tcaggcaatt
      361 gattgcccaa ggcgcggaaa tcatcttgag tgactaagta gacatagcct gtagtgactg
      421 gactaggatt tagcaaggat tctttggtta ctacaatggt ttctttttgg gatacttcaa
      481 aagaaaccat gctactataa tagactagaa aatccgaggc aggcttattg gtcttttcaa
      541 caataagtct gttaaaaacc tctttttgat tgtcaatctc tgaattatca aaattaatat
      601 gagtattttt aggaaaaagc tggttagaca ttgcctcgct attagcataa agcgcagttg
      661 ttgttgctat tgcaacaaag gccataacag ctaagagggt aatatttgcc aagcctacag
      721 cattttgctt cattctaaaa atcatctgag aggtgctgac aaaatgctct ggctggtaaa
      781 aataagcctt gttttgacga cgacgcttta agtgccaagt cataaaggaa atgtaaaaga
      841 gataggtccc gataataacg ataataactg ctataaaaaa ccgatataaa gtgtctaatg
      901 ctgtcagctt tgtcgatgat aaggagatgt aatagccaat actaagcaat atgatggata
      961 aggctgctag taataaatta ccctttggct ctttttcacc ctgttcttta tgacgaaaga
     1021 gcattaaggg agaggtcttt ctgattttaa tcaagccaac aacctctaat aaaccaaaga
     1081 tagcagcaaa gattaaagtg gtgtaaataa aagcaacggg attgatttgt aattctaaat
     1141 ggactgctcc gaccagatta gcgaaaatca aataaaagac gtgtgaaaaa atagctgata
     1201 ggatacttcc tacgactact gtccctaagt acataaaaac aagctcgatc gttgagacta
     1261 aaccaacctg ctttttattc attcccaaaa tattgtacag accaaattct cgacttcttt
     1321 gctttagtaa aaaattatag ctataaatct ccataatagt ggcaaagatg attaaaacaa
     1381 agattgctag tcctaatagc ataaacccat gtctcatcga ttctgatacg gggctcatca
     1441 tgataatcaa gacaatacaa ttgagcatat ataaaacagt gcttgccagt aaaaaaggag
     1501 ctgtgacgga taaggacttt cgtagattat tccaagctag tttgagataa aacatcttta
     1561 ttcacctcct aaaagaccgg ccatggcaat cgagatgtct ttgctaaatt ctaaattcgt
     1621 tttatttcca cgatagattt ggtggaaaat acggccgtcc ttgataaaca gtactcgctt
     1681 agcatggcta gcagcattgg cagagtgtgt taccatcaag agtgtctgac cgtctaggtt
     1741 aatggcctca aaaagattga gaatatcctc tgaattgcgg taatcaagtg ctgctgttgg
     1801 ttcgtcagct aataataatt gcggattggt gattaagctt cttgcaatag caaccctttg
     1861 cttttgacca ccagaaattt caaatggacg tttatctaaa agcgtttcaa tgcgcagctt
     1921 aggggcaatg atgttgagcc gtctttccat ttctttaaat ggcttacggt ttaaaacaag
     1981 gggtaaaaag atattatctc tgatcgatag ggtgtctagg aggttaaaat cctgaaaaac
     2041 aaagcctagg ttttgaagtc ggaaattagc taggtcaccc tccttaattt ttgtaatgtc
     2101 agtgccattc aataaaacag atcccttggt tggtttttcc agagttgcca gaatatttaa
     2161 tagggttgtt ttccctgagc ctgactctcc catgatggca ataaactcac ccttgtcaac
     2221 cttaaaatca acatcttgta aggctctagt ttcttccttt gaaaagcgtg tccgaaaaac
     2281 cttctctaaa tgattaattt ctaataacat atgaaactcc tttgtgtcta ttatactctt
     2341 ttagctttaa atatagccac tatcgtgacg tatttagcta gtgatgcatt tagtgccttt
     2401 tgtcagcctt aaccactcct tctttcatga agcagcccag ctctcaacaa gaatcgtctt
     2461 agctgactga acctattgct ctaaactctt ttttctttac agcttatagt ttaccctaat
     2521 taatagtctg gttagcttac aagatttgat gggtgactta cagatttgta agttttataa
     2581 catcattttt cttatcattt tgatataatg aaaggagaat tctatttagg agaagcgtca
     2641 atggctaaga aaatcaaaaa aacgctaggg actgtcggaa agctgttttc cattatccct
     2701 gataccactg aaattatagg aaaaacgata gataacaccc gtcccattat cgaaaagcat
     2761 atggaacaaa agcatgaaaa ggaaatgcag ctaacgcttt tagatgatgt gattaattta
     2821 cctgttgata aagcgcaaaa gcatctggaa cagctaggtt ttgttgtcgc actattgccg
     2881 gtcaagccta gtaaaaaatg gatacatgct agcttaaatg aggttgtttc catgtcacct
     2941 aagcctggaa agcataagct gggaagctta gtaaagcttt attatgttac tgtagatgtc
     3001 cttgagaaaa gtcaggctat tttagatcaa gagaccctaa aggctgtcga acgaaatcaa
     3061 aaaatcgctg ataccatcga agctgttaag caaatcaagc ttccttttaa aaagagataa
     3121 ggctatactg taaaaaataa gctgataccg ttaggatcag tttatttttt atgttgtgac
     3181 tttaagtcta tctcgcttag caggtgccaa acaaataaac cacccgttat gtaccgacct
     3241 tcaatggtta aagtt
//
LOCUS       DARYLD010000095         3130 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYLD010000095 DARYLD010000000
VERSION     DARYLD010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3130
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            30..2216
                     /locus_tag="TU651_001867"
     CDS             30..2216
                     /locus_tag="TU651_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL0897823.1"
                     /translation="MKNFKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGN
                     AYQVFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSD
                     FITVSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKR
                     ASFAVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQ
                     KERNGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDD
                     DKDYEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYG
                     GENTQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKN
                     SFQYGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDD
                     ETINGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGK
                     DPETWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQL
                     GQDLLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRA
                     AVAQQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIY
                     SKNGNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
     gene            complement(2328..3047)
                     /locus_tag="TU651_001868"
     CDS             complement(2328..3047)
                     /locus_tag="TU651_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0897824.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
BASE COUNT          940 a          686 c          578 g          926 t
ORIGIN      
        1 taggaaaaaa tgataaggaa gttcttactg tgaagaattt taaaacattt atcacaagct
       61 ttatcaatac aagattaggc tttgtgctaa cgcttctctt ctgcttttgg ataaaaaccc
      121 tatgggctta ccatgctgac ttttcactag atttgggaaa tgcctatcag gtctttctaa
      181 caattattaa cccaatccct ctagctttgt tactattggg atttaccctt tatatcaaga
      241 atactagggc cttttatatc agctcttgga tcgtctatat tatccttaac ctcttgttaa
      301 tatcaaattc tatttattac cgagagtttt cagatttcat tacggttagt gctatgctag
      361 ccagtagtaa ggtttctgct ggtttaggag actctgcttt aaaccttttg cgcatttggg
      421 atattgttta cgtccttgat ttcatcattc tgattagttt atcagtaact aagaccatca
      481 aaaaagaccc gcgtcctttt aacaagcggg cttcctttgc tgttacagca ctgtcttgct
      541 tgctcttatc tgttaatctg tttcttgcag agattgaccg cccggagctt ctgactagag
      601 gattttcaaa tacctatatc gttagagcgc ttggattgcc tgcttttacc atttacagcg
      661 gaaaccagac ctatcaagca caaaaagagc gtaacggagc aaccgctgaa gaattagtcg
      721 atgttaagca atatgtcaag aaccactacg ccgcacctga tcctcaatat tttggaatcg
      781 gtaagggaaa aaatgtcatt gtgatccact tggaaagctt ccaacaattt cttattgatt
      841 acaagctcaa ggatgacgac aaggactatg aggtcacacc ttttattaat tccctctacc
      901 actccaatgc cacactagcc ttctctaact ttttccatca ggtcaaggct ggaaaaacgt
      961 ctgatgcaga gaccatgatg gaaaattcat tatttggctt aaacagtggt tcttttatgg
     1021 taaattatgg cggcgaaaac acacaattcg ccacaccatc aatcctagca caaaatggcg
     1081 gctatactag tgccgtcttt catgggaatg taggaacctt ctggaatcgc aataatgctt
     1141 ataagcaatg gggctatcat tacttttttg attcaagcta tttttcaaaa cagactgata
     1201 aaaactcttt ccagtatggc ctaaatgaca aatacatgtt tagagattct atcaagtacc
     1261 ttgaacagct tcaacaaccc ttctacacta agtttattac cgtcagcaac cactaccctt
     1321 acaccagcct tagaggcgaa agcagtgaag agggctttcc actagccaaa accgatgatg
     1381 aaaccatcaa tggttacttt gctacagcta actatctgga ttcagccttg aaatcatttt
     1441 ttgattatct caaggcgaca ggactttatg acaattctat ctttgttcta tatggtgacc
     1501 actatggtat ttctaattcc agaaatgtca gcttggcaga attactaggt aaagaccctg
     1561 aaacttggtc cgaatatgac aatgcaatgc tccagcgtgt accatatatg atccatattc
     1621 caggctatac caatggcggg atcaaagaaa cctttggcgg agaaattgat tccttaccaa
     1681 ccttactgca tatcttgggc attgatacca gcaagatggt tcaactagga caggatctct
     1741 tgtcgccaca aaatagtcaa atggtagcac aaagaacctc tggaacttat atcacgccag
     1801 actacactag ctatagcggt cgcctttaca acactcaaac aggcttggaa attacaaacc
     1861 ctgatgagat gacaatggct aaggtcaaag aaatacgagc agccgttgct cagcagctag
     1921 cagctagtga cgctatccaa acaggagacc tactacgctt tgataccgat aatggtctga
     1981 aacctgttga cccaacaacc ttcatttata ccaagcagct aaaacaactc aaagagatat
     2041 cagagaaatt aggatcacat tcaaccagca tttatagtaa aaatggcaac aaatcaactc
     2101 aaaagctctt taaagcacct tcttatctgg agttaaatcc taaagaagcc gaaaaacctg
     2161 aatctacttc gtcttctgac cctaaagaag aatccgttaa ggaacaaagt cagtagtgga
     2221 tgtctaaagc aagcctcact aggatcgctc tcgtagaaga ctaaaagcaa gctaaaagcc
     2281 ttcattgagc gttacaactt aatgagggct ttttagttct gacactttta ttgaggaatg
     2341 gcctcaaagt attctggatc tggtgtcggt tcaggtgttg gcacaggatc tagcttaggc
     2401 tcaggcttcg gttctggtgt tggcacagga tctggcttag gttcgggtgt cggtgctggg
     2461 ctattttctt gcgtcacaat ataacccaca taacagtaat catcaacctt ttcttctgga
     2521 gtgtaagtaa agcttacccc cttaaccgta gtcttagtga cgatatcatt gagatgacgt
     2581 accacatcaa ctgcactaac agctgttgtc gcaccaccag ctaccaacaa ggcaatcaac
     2641 acatagctac cgcttttcct atttttgtaa ataagatagc ctgaaacact tagtaagcct
     2701 agccctactg ccaaaccaac cagaccatct gctgcaccac ccgttttagg caagacctta
     2761 gcgttagcct taggggtaga catcattcct tttggagatg ctgtcactcc acagcttttg
     2821 tcgtaaacaa gaacgtaatg caatttatct tggataggta cttcatttgg agtgcctttt
     2881 tgaatgcctg ctttttgttc atttgtcaga ttagaatagg ctgtataggt caaatctacc
     2941 gttaccgtat cagcattagt gttggcattg acattagctg ctagcaaaga tagacctaac
     3001 atcgttgtag ctcccatgta ttgaaacgct ttagaaaaac gtggcattat aactattctc
     3061 cttaatgttt tgtagaataa aaccaataac taaaaaggca tctcctatca tatcaatctt
     3121 atgattatta
//
LOCUS       DARYLD010000096         3059 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYLD010000096 DARYLD010000000
VERSION     DARYLD010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3059
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            121..594
                     /gene="tnpA"
                     /locus_tag="TU651_001869"
     CDS             121..594
                     /gene="tnpA"
                     /locus_tag="TU651_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL0897825.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            881..1346
                     /gene="tnpA"
                     /locus_tag="TU651_001870"
                     /pseudo
     CDS             881..1346
                     /gene="tnpA"
                     /locus_tag="TU651_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(1528..1683)
                     /locus_tag="TU651_001871"
     CDS             complement(1528..1683)
                     /locus_tag="TU651_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL0897826.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1777..2976)
                     /locus_tag="TU651_001872"
                     /pseudo
     CDS             complement(1777..2976)
                     /locus_tag="TU651_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
BASE COUNT          970 a          479 c          602 g         1008 t
ORIGIN      
        1 ttctcgtaga gaaaaacaag aaaaccacca gctatgctgg tggctgacaa ggctttgagc
       61 ttccatttct ttttcctgtt ataatctaat tgttcaggtt agatcaagga ggaaaaagag
      121 atggctaaaa ccagttacag tttatcacat accaaatgga tgtgcaaata tcacatagtt
      181 ttcacaccaa agtaccgcag aaaatccatt tactacaaaa ttagacagga cttaattgat
      241 attttccgtc acctatgtca atacaagggc gtggaaatca ttgagggaca tatgatgcca
      301 gatcatgttc atatgctcgt cttgctacct ccaaaacttt cgatttccga tttcatgggg
      361 tatttgaaaa gtaaaagtgc tctcatgata tttgataaac acgctaattt aaaatataag
      421 tatggaaatc gaaagttttg ggctagaggc tactatgtta gtaccgttgg actgaacaaa
      481 aggacggtag cgaaatatat tcgcgagcag gagaaaaatg acattgcact tgataagttg
      541 agtgttaaag aatatgaaga tccattttca gatggcagtt ttaaaacaag ataaaagccc
      601 gtttttacgg gcattagtca agtaatcata gcactaacct gaacgaagtt cagcgaacgt
      661 ctttagacgt cgctggagag aaacggctta tagccggtgt acaagccacc cgtttttacg
      721 cgtggttatg acttagtgac tttagtccgt ttcgctccgt aggtgcgaaa caaaaatccc
      781 ccgctatgcg ggtacgcatc gaacgttata ctacaaaaaa actccaaacg cgctacaata
      841 taggtgttca agccaattgt aaagcgaaag gagtaaaaat atggcacaaa agccccacag
      901 tttatcgcac acaaagtagc attgtaaata tcacattgtg ttcaccccta agtatagacg
      961 aaaagtaatc tataatcaat atcgaggcag tttgggagaa atttttcaaa gattatgtag
     1021 ctataaaggt gtagaaatat atagaaggac atctgatgcc agatcacgta cacgtgttag
     1081 taagcattcc acccagaata agtgtttcaa gttttatagg atatttaaaa ggtaagagta
     1141 cgcttatgat gttcgacaag cacgccaatc tgaaatacaa atttggtaat cgacactttt
     1201 gggcagaagg ctattatatt agtacggttg gattaaatga agctacaata aaaaaatata
     1261 ttcaagaaca agaaaaacat gacatagcac tagataaact gagtgtaaaa gaatatgagg
     1321 atccctttag agataagggt aagtgataca aatacttctt tgagaggcaa gtgacgagtc
     1381 aatagcaatg tggtttgaac aaagtgaaag ccagcgtctt taggcgctgg ctagttatat
     1441 gggtttatag tccctattca aaccacctgt tggacgggtg gttatgattt ctactaaaaa
     1501 aactattatt acaatactaa gtatatgtta gacaataata ttattagaac ccacggaggt
     1561 atgtttatat ttttgagagc gattaaaatt taatatctct gaccaccaat ctccacctgt
     1621 tatttgattg agttcggatg aatttagttc ttgaaattga gtgagtgaat tttgtttttc
     1681 catttgtgga cctccttctt ttttctaata ttataattta agatcaatat attatttctc
     1741 taaatcctaa atggtcatcg aaacgtccgg aatggtttaa tcatgatttg acaacagttt
     1801 attcttataa aagtcgaagt aggatttttt agcgataaca cttgtaacac gaccctgtgc
     1861 accatatttt atcaagtagc tatccttgga agggagtttg gcaagagttg taatcttgaa
     1921 aagattacct tgttctgttt ttgttgctgt tttatcaata gtagaaattt ttccattaac
     1981 agtgatggac tgttttctca ctttttgaag atttagacga acagtttgac cttttttaag
     2041 gagagaaaca taatcagaag ttacaaagta tgtaatcaga gcttttctag tttgagtaat
     2101 attaggatag attttggcaa tatcactacc atttgggata agacttttcc cctcgtattc
     2161 attatttaga tgaataatcc tggtttctgg tgctaaaaca acattagtgt ctaactatac
     2221 acttgcttgt tctagctgag ctttaagttc agtgatttga ctgtcgatgg ttgacagctg
     2281 ttgtgaagca ttctgtagaa attgagtcct caagacttca actttggttt ctgaactgtt
     2341 atcgtatgtt gcactactac cagtacctgc tctttgaatg ctaagcccag agagggatga
     2401 ttctaaacct gaaatagtct ggttaatctg agagataaac tggttagacg tggaagttta
     2461 ttcttcttgt gattgagaca gataattatt gagaatatct tgatgaggat taccagttgg
     2521 taagattgtg ttatgatttg agatagcttg acgaagatct tcatattctg aaatctgctg
     2581 gtttatagta ttgatttgag tatcaattgc agcaagggtg ttatttgcaa gtgtggattg
     2641 attggatact tctgtattta ttttagcgat accaagttta atctcttgag actgatttat
     2701 aaagttgttg aaggtgtcag caagaccaaa ttcatcattt tgtggtaaga ggttcgttcc
     2761 ttgtttgaga ctttctttca atgtctctaa accaactttt tgtttattca acgtatttaa
     2821 ttgtgattct agagaattct tttgagaact ctcaatggtt tctttatatt tgattaaacg
     2881 ttttcctttt ttaacgagtt ggttttcttt aagattattt ttaacgatag cattgttgct
     2941 agttgactgt attgatgcaa tgacttttgt aggcataatt tcacctcgtg acgataccgt
     3001 tacttctttt tgaccaagaa aagaaaatga aagtaaaaat atgacgaata atgttaatg
//
LOCUS       DARYLD010000097         3010 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYLD010000097 DARYLD010000000
VERSION     DARYLD010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3010
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(210..1046)
                     /locus_tag="TU651_001873"
     CDS             complement(210..1046)
                     /locus_tag="TU651_001873"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897827.1"
                     /translation="MNNLYATINKLNKVEQSVFLVINDIIDNNTVFPDVNARNSLKKI
                     AISTLGDRTFSTPYDFISEHIYNNADLNSVQDDEMLVKNIEILKNYALQNNFENFDYS
                     LFIKNLNKIHRHYKLALIQKNFILRTTTEVEERAHDLKDKTKAIEQKMFKFDEIKSSI
                     YTDFIAILGVFSAFVFVMFGGIDVARAIFDIGSDLQTLDLSRMITIASLMLIGILTLM
                     YSLLLWIARITGKNFGNCYSSKCDNGCQHKWRHFLMRHSFYFSLMGLLIVVILFSHYV
                     FK"
     gene            complement(1050..1592)
                     /locus_tag="TU651_001874"
     CDS             complement(1050..1592)
                     /locus_tag="TU651_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL0897828.1"
                     /translation="MTEALFVANYIIEYCNDHNLEINNLRIQKLLYFINARNLVENGS
                     PLFQDKIEKWKFGPVVPKVYHEYKRFGASTITKDDISAQIWKFNFEVSPFGEESPIEV
                     LTYNKEEFSDSQIQLIESTILALKKYSTFKLVDLTHEDDMWKSDNQLIMSGEKGLTYD
                     NNEIRDFFMSHIESQIWNNI"
     gene            complement(1727..2923)
                     /locus_tag="TU651_001875"
     CDS             complement(1727..2923)
                     /locus_tag="TU651_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL0897829.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYH
                     AVIGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDKEALKTNKEVTMTTA
                     NEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLWGNAIDLLNSASAQG
                     LEIIYNAPGVNPRAGDLFVMEVAGSPYGHTGAVIEDSDGYTIKTVEQNIDGNWDSLQV
                     GGPARFNTRDFTGVVGWIRLPVDHTKQTVDTAPQTSDTIVETPKTGTFTVDVAEINIR
                     RWPSLASEVVGSYKQDDTVSFDSEGYANGYYWISYVGDSGKRNYLAIGQTDKDGNRIS
                     LWGKLN"
BASE COUNT          947 a          608 c          476 g          979 t
ORIGIN      
        1 aattaaatat agtggtaatt ttaaatcaac gtatttgaaa tatttggtag ctactatttc
       61 ctgaaaaaga aataaacaaa cgggcgtatg acgggttctg cattcctcct tcataggtta
      121 ataaaaattg aagatgaaag aaagaaatta aaaaaaataa ttccttaaaa aacacaaaaa
      181 accgccctca atcaagagag cggttggttt tatttaaaca cataatgact aaaaagaatt
      241 acaacaatta gtaatcccat taaagagaaa tagaaagaat gtctcatgag aaaatgacgc
      301 catttatgct ggcacccatt atcacatttt gacgaatagc agttaccaaa atttttgcct
      361 gtaattctag ctatccaaag cagtaaagaa tacataagcg tcaatatacc aattaacatt
      421 aagcttgcaa tggtaatcat tcttgataag tccagagtct gaagatcact accaatgtca
      481 aatatcgctc tcgctacatc tatgccacca aacataacaa aaacaaaagc tgaaaacaca
      541 cctaagatag caataaagtc tgtgtaaatt gatgatttta tttcatcaaa cttaaacatt
      601 ttttgttcta tagcttttgt tttgtctttg aggtcatggg ctcgctcttc cacctctgta
      661 gttgttcgca aaataaaatt cttttgaatt aatgctagtt tataatgtct atgaatttta
      721 tttaaatttt tgataaacaa agaataatca aagttttcaa aattgttttg taatgcataa
      781 ttttttaaaa tttcaatgtt tttaacgagc atttcatcat cttgaacact gtttaaatca
      841 gcattattat atatatgctc agaaatgaaa tcgtatggtg tactaaaagt tcgatcgcca
      901 agtgttgaaa tagctatttt ttttaaacta ttgcgagcat ttacatcagg gaaaacagta
      961 ttattatcaa taatgtcatt aattactaaa aaaacagatt gttctacttt gtttaactta
     1021 ttaatagttg cataaagatt attcatttgc taaatattat tccatatttg agactcaatg
     1081 tgcgacatga aaaaatctct tatttcattg ttgtcataag ttaaaccttt ttcaccagac
     1141 attatgagtt gattatcaga tttccacata tcatcttcat gtgtcaaatc tactaattta
     1201 aatgtgctat atttttttaa tgcgagtatt gtactttcaa ttaattgaat ttgagaatcc
     1261 gaaaattctt ctttattata tgtcaatact tcaattgggc tttcttctcc aaaggggctt
     1321 acctcaaagt tgaatttcca aatctgagca gaaatatcat ccttggtaat tgtagacgct
     1381 ccaaatcttt tatattcatg atagactttt ggaacaaccg gtccaaattt ccatttttct
     1441 atcttatcct gaaacagtgg gctgccattt tcaactaagt tccgagcatt tataaagtat
     1501 aaaagtttct gaattcttaa attatttatt tctaaattgt gatcattgca atattcaatg
     1561 atgtaatttg ctacaaacag tgcctcagtc atccagtcca cctccttttt ttaattataa
     1621 catatttgtc aagtactata tcttgttagc taacttttta gctaacacta catattgatt
     1681 ttgataataa aaacagcccc cgcaaaagcg agggcgtttg tcttatctaa tttaatttac
     1741 cccaaaggct gatgcgattg ccatctttat ctgtctgtcc aatagctagg tagttacgct
     1801 tgcctgagtc gccaacatag ctaatccagt agtagccatt agcgtagccc tcgctatcaa
     1861 aactgacagt atcatcttgt ttgtagctac ctactacttc actcgctagg cttggccaac
     1921 gtctgatatt gatttctgcg acatctacgg taaaagtacc tgtttttggt gtctctacga
     1981 tagtgtcaga cgtttgcggt gctgtatcta ctgtctgctt agtgtgatca accggtaatc
     2041 taatccagcc gacaacacca gtaaagtcac gagtattaaa gcgagcggga ccacctacct
     2101 gaagactatc ccagttaccg tcaatatttt gctcaacggt tttaatagta tagccatcac
     2161 tgtcctcaat aacagctccc gtgtgtccgt agggactacc agctacctcc atgacaaata
     2221 agtcaccagc tctaggattg actccgggag cattatatat gatctctagc ccttgcgcag
     2281 atgcactatt taacaggtca atcgcattac cccataaatc aatgccgaac cagtttttga
     2341 cgataaaaca tggcaagtcc gcacactgcg tcccaaaaca gccatcttta tcaacaccca
     2401 tgcctgaatt ggctaggtcg acacagtatt gtacaatctc atttgcggtt gtcatcgtta
     2461 cctccttatt agtttttaag gcttccttat cccatttttg caagttgttt tcctcaatca
     2521 actggataag cagctctgca taatcacttg cagtggcata accagctgct ttaatggcat
     2581 gacaggcctt tttatagtca gtctctccaa ttacagcgtg atagcgtgga ttatccacta
     2641 aaaactggcc atgatcaagg attgactcgt cccaactatc ataggctcta aagcggtcca
     2701 cgagatccgt cacgacacct ggctgatact cctcttgtgt cttggtatca aaagatttac
     2761 cagaccatga gctatctgcc ttgataccaa acaatgcgtt atgtggggca tacttgcccc
     2821 aaccactctc taagattgcc tgcgctgcgg ttaacgatgg caaaatctta tgattgtgcc
     2881 actctgcgat aactgcgctt tttatgtcgt ctaaaaaggt catctgtcct cctcatctaa
     2941 aaacgggtaa acaatcagag caatcacaga cacaggtaaa tatagcactg cgattactat
     3001 gactaagact
//
LOCUS       DARYLD010000098         2665 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYLD010000098 DARYLD010000000
VERSION     DARYLD010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2665
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..1448
                     /locus_tag="TU651_001876"
     CDS             <1..1448
                     /locus_tag="TU651_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897830.1"
                     /translation="QIVVCVCTIMAWFIMIWSYSYFKSYYVKKVILDLKERLFIGYLL
                     REFNEIDTCDRYNSDFLNNVTKNIDIIQENLLVPRVAVIVDLASMVTSVVAIVLIEWR
                     LALVFLLLSIVTVFLSQIPGKLMSKATRYYSEKSNHYLAEMTSFIEGFEQIKLLNIQK
                     WIQKIEQNTTLEFEDSRQKYQYRKDLASNTGMFLSFFSQVACMVAGIFFVRNNLLTVG
                     LLVASIQLLNGVFGPLQSFLYNKNLIKSTGTILTSIQEVLDKTNFVNGYIENKTFYEG
                     DISSISINNLTYQVENRKIFTNFSFEFKKGNTYAIIGPSGVGKTTLAKLILNYYPKHL
                     YDGEIRIDGRNIAEINSESLYKKIAFVQKNDFLVEGNVSDNIKLDGSLNLTDKLKDSL
                     GFDETFLNKKLFRVQSLISEGEKQRIDLARFLNRRYSIYIFDEPTGNLDPARSKAILD
                     YILSIKNAIIIVITHNQDIKTLEQFDEVICL"
     gene            1611..2665
                     /locus_tag="TU651_001877"
                     /pseudo
     CDS             1611..2665
                     /locus_tag="TU651_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          982 a          289 c          484 g          910 t
ORIGIN      
        1 ttcagatagt agtgtgtgta tgtaccataa tggcatggtt tataatgata tggtcctatt
       61 cttattttaa gagttattat gtaaaaaagg tcattttaga tttaaaggag aggcttttta
      121 taggttattt attacgggaa tttaatgaaa ttgatacttg tgatcgatat aattcggatt
      181 ttctaaacaa tgtaacaaaa aatattgata taattcagga gaatttattg gttcctagag
      241 tggctgtgat tgttgatctg gcttcaatgg ttacgagtgt agtagctatt gtacttatag
      301 aatggcgatt ggccctagta tttttattgc tttctattgt aactgttttt ctatctcaaa
      361 ttcctggaaa gttaatgagt aaagcaactc gatattattc tgaaaaaagt aatcactatt
      421 tagcagaaat gactagtttt attgagggat ttgaacagat taaattattg aatattcaaa
      481 aatggataca aaaaatcgaa caaaatacta ctttagaatt tgaagattct agacagaaat
      541 atcaatacag aaaagattta gcttcaaata caggaatgtt tttgagcttc ttttctcaag
      601 tagcctgtat ggttgctggt atattttttg taaggaataa tctactaaca gttggactat
      661 tagtggccag tattcagtta ttaaatggag tgtttggccc tctacagtct ttcctttaca
      721 ataaaaattt gatcaaaagc acaggtacta ttttaacaag tattcaagaa gttctagata
      781 aaacaaattt tgttaatggt tatatagaaa ataagacttt ttatgaagga gacatctcca
      841 gcatttcgat aaataattta acttatcaag ttgaaaatag aaaaatattt actaattttt
      901 catttgaatt taaaaaggga aatacttatg ccattattgg tccttcgggg gttgggaaaa
      961 caacattagc aaaactgata ttaaattatt atccaaagca tttatatgat ggggaaataa
     1021 gaattgatgg aagaaatatt gctgaaatta actcagaaag tttgtataag aagattgcgt
     1081 ttgttcaaaa aaatgatttt cttgtggaag gtaatgtttc agacaatatt aaattagatg
     1141 ggagtttgaa tctaacagac aagctcaaag atagtttagg atttgatgaa acatttttaa
     1201 acaaaaaatt atttagagtt cagtctttaa tctcagaagg agaaaaacaa agaattgatt
     1261 tagcaagatt tttaaaccgt agatattcta tttatatttt tgatgaacca actggtaatc
     1321 ttgatccagc tagatctaaa gccatattgg attatatttt atcaataaag aatgcaatca
     1381 tcattgtgat tactcacaac caagatataa aaacgttaga acaattcgat gaagtcattt
     1441 gtttgtaaat gaaagggggt gatgaacatg attatggaag attttgaagt tttagaacta
     1501 gagtttgtcg aagttcgaaa tgaacaaacc acaaattggt attttgttta atcacaaagg
     1561 catgcaatga gaatttgcat gcctttgtaa aatatagaaa ggacaataaa atgaataatt
     1621 tttttccaaa atggaatcag gataggattg tatattcatg gcaaaatgat aaattaagga
     1681 taggagctga tgataatgat gttctagaaa tcaaaggaaa ctcaattttt tggtcagatt
     1741 ttatttcttg ttgtgacggg aataatagta tcaaagacat tcaaaaacta ttgaatataa
     1801 aatataatat ttcagaagaa ataattacag agtatttaga taaattctca aatcgaaatt
     1861 tattggaaat attggataat ccaataaatc aattacagga ttataaatca attgagtcgt
     1921 tagaaacata ttatgctagt gaaggaattg gtgggattaa actattaaaa atgttaggga
     1981 atctaaagat ttctattctg ggatgtggtg gtggtggatc tcatattgca ttacaattag
     2041 ctcaattagg agtgggaaga attcatttgg tggattacga tattgttgaa gaaaacaata
     2101 tcaacagaca atccatgttc acatttaacg atgtcggaaa ttacaaagtt gattgtgtag
     2161 ccaaaaatat tcagcaaaga aattctaaat gtttggttac caaaagcact tctaaaatga
     2221 ttaatgtacc tgatgtaaaa aaaagaaata tctgaaagcg attgggtatt ctgttgcatg
     2281 gatgaacctc cttatatagc acagaggatt gtaaatagag catgttattt attaaaaatt
     2341 ccaagtatat actgttttag ccaacgtagt gcggggaaac ttttgttttg taatcctaat
     2401 attgaagatt ctggctgtat tgattgtttg ttatctgaac aagataatga aaactttcaa
     2461 aagctggtga caacgttcac tacctataat aggaaattgg taactgcaaa tatcttacca
     2521 aatattttat tattgacatc gtgggtggtt aaacgatggt tagattgtgt aacagataaa
     2581 aatagtaatg tatggaatat gttgttgaga tttgattttt ataaatatat ggaagaaaaa
     2641 tttcaatatt tttcgaaaca agata
//
LOCUS       DARYLD010000099         2664 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYLD010000099 DARYLD010000000
VERSION     DARYLD010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2664
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            11..1432
                     /locus_tag="TU651_001878"
     CDS             11..1432
                     /locus_tag="TU651_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL0897831.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRKLFREVLEGDLLTKTFLFLGFSFEDPNFNYVIGRLRVLLDE
                     KNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTYLVNKYDEITEILSTLV
                     DRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYHIVNGYGKGVGEFVLNG
                     VADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQMIESCGIAIFLFGNKEA
                     EDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEISDKNTISAIEQANKQC
                     DGDIDMSVKNIVQAVKILNKEEF"
     gene            1433..1930
                     /locus_tag="TU651_001879"
     CDS             1433..1930
                     /locus_tag="TU651_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL0897832.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(1954..2352)
                     /locus_tag="TU651_001880"
                     /pseudo
     CDS             complement(1954..2352)
                     /locus_tag="TU651_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2432..>2664
                     /locus_tag="TU651_001881"
     CDS             2432..>2664
                     /locus_tag="TU651_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL0897833.1"
                     /translation="MEYIERPKYLNHIEKFVDKPIIKILTGMRRVGKSTILMMIKDEI
                     LKHVPDEQKIYINFESLEFMSINEASFLASYIS"
BASE COUNT          999 a          303 c          508 g          854 t
ORIGIN      
        1 aagggaggag gtgtttatta ttaaaggtga agtatccaga aaagatttga ttagagaaat
       61 tgaaaaagct attaaaagtg atgaattagg agcatttatt ggagcaggat tatcaattcc
      121 tgccggattt tgtagttgga aagaacttct aagagaacct gcagaagaaa ttggattaga
      181 tgttgaaaaa gaaagtgatt tggttaactt ggctcagtat tattctaatt caaaaaagag
      241 aacatcaata gatgacttga tcaaaggtca attttctcaa ttagtaaagc ctactgaaaa
      301 tcataaatta ttgtcgcagc tgcccatttc aactttttgg acaacaaatt atgataagtt
      361 aatagaaaaa gctttagaaa ataatatgaa aaagccttat gtaaaaacaa aggatgaaca
      421 attaagaggt acaaatcata attttgatgc gatagtatat aagctgcatg gtgatgtaga
      481 aactcccgaa gatgcagtaa taacaagaag tgattatgaa gagtttggat ataacaaaag
      541 aaaattattt agagaggttt tagaaggaga tttgcttact aaaacatttc tatttttggg
      601 atttagtttt gaagatccaa attttaacta tgtaattgga aggttaaggg tcttactcga
      661 tgaaaaaaat acaagaaaac attattgtat tatgaaaaga gtccaagatg ctgatgagga
      721 ttatgaatac aaaaaagcaa gacaggagct acaaattgaa gacctaaata gatatggtat
      781 ttttacatat ttagtaaata aatatgatga aatcaccgaa atattgagca ctcttgtcga
      841 tagatttaga aggaaaacaa tatttatatc tggtagtgcg tactcctatt cggcttattc
      901 tcagaaaact ggcgaaaatt ttattcataa actatctttt gaactatcaa aaaatggtta
      961 tcatattgtg aatggatatg gtaaaggagt cggtgaattt gtattaaatg gagttgcaga
     1021 ttattgtttg actcacaagt ccaaaataaa tgatttttta acacttatgc cttttcctca
     1081 aaatagttca ttaggtattg atttagataa gctatataaa gaaaatagag agcagatgat
     1141 tgaaagttgt ggtatagcta tatttctttt tggtaataag gaggcagaag atattgcaag
     1201 cggagttatg gacgaatatg agttatcaaa aaagcatgga ttagtatgtt tgcctattga
     1261 atatactggc ggtgcatcta aagaaatata tgatcaaaca actcaagaaa tttcagataa
     1321 aaatacaata agtgcaattg aacaggcaaa taaacaatgc gatggcgata ttgatatgtc
     1381 tgttaaaaac atagttcaag cagttaaaat attaaataag gaggaatttt aaatggcaaa
     1441 aagacaggta ttttttagct ttcattacga caatgataat tggagggcag gacaggttcg
     1501 caatatgggg aaagtagaca gtagttctac cttttctgat aatgactggg aggaagtaaa
     1561 agaaaaaact gaaagtaaaa ttaaagaatg gattgatgaa cagttaaata agcgttcatg
     1621 tttggttgtt ttgattggag aaaaaacagc gaacagaaaa tggataaatt atgaaataag
     1681 aaaagcatat gagttaaata aaggtattgt gggaatttat attcacaagt tggagaattc
     1741 actgggagag caagatgata agggtaataa tccttttgat tatttaacat tagaaggtga
     1801 aaaactttca aagtatgtta aatgttttga ctccaactat tcatcaagta aatatgttta
     1861 tagcgatatt aaagataata ttgaaggttt aattgagtat ggaataaacc ataaaccatc
     1921 aacttggtaa taaatgatga tggagagaaa aaattatctc tccatctcct tacccatgta
     1981 aattccataa ttttttcgta tcttgtaaag ttcgtccata atagattttg aggaagaata
     2041 ctcttgcata agggtattct ttttttcttg caatttatca agtctatcta aaataccctt
     2101 agaatttggc aacttggaat atgatttttt aagctctgaa agggcatttt catataaggt
     2161 aatctgagct ttgtactctt caaaaaatgc cttgtcagat ggacttgcct tatattcttt
     2221 gtagtattgc ctgtattttt taacagtgtg aacttgctcc atagtggcag aaagctcctg
     2281 catttcctta tcaatagcct tgatcttatc ctgtaaattt tgcctttcat cggctgcttt
     2341 tatgatatat ttcgattata ttcgaaaaca atattggaaa atatattttt atcgtgtata
     2401 atataatcaa agctaaagag aggtgaatga tatggaatat attgaacgac ccaagtattt
     2461 aaaccatata gaaaaatttg ttgataaacc tattattaaa atcttaactg ggatgcgaag
     2521 agttggaaaa tctaccattc tgatgatgat taaagatgaa attttgaaac atgtgccgga
     2581 tgagcaaaag atatatatca attttgaatc tttggagttt atgagtataa atgaagcgag
     2641 ctttttggca agttatataa gtga
//
LOCUS       DARYLD010000100         2472 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYLD010000100 DARYLD010000000
VERSION     DARYLD010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            50..1003
                     /locus_tag="TU651_001882"
     CDS             50..1003
                     /locus_tag="TU651_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL0897834.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1063..2262
                     /locus_tag="TU651_001883"
     CDS             1063..2262
                     /locus_tag="TU651_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL0897835.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          745 t
ORIGIN      
        1 ggctagtggt attcttttca tttcagcctt attttgatat gatagacgta tgaattttga
       61 aaagattgaa caagcctatg agcttatatt agaaaatagc cagctgattg aaaatgattt
      121 aaaaacgcat atctatgatg ctattgttga gcagaattct ttttatctgg gagcccaagg
      181 agcaagccct caggttgcta aaaatattga gacgttgaag gccttgcagt taaccaagga
      241 ggagtggcgc caggcttatc agtttgtttt gatcaaggct gggaaaacag agccattaca
      301 ggccaaccac caatttaccc cagacgcgat cggctttatc atgctttata ttttggagac
      361 cttgagctca caagagtcac ttgatgtgct tgagattggc agtggaacag gtaatttagc
      421 tcaaactatt ttaaaccact cacataagag cattgattat ttaggcattg agcttgatga
      481 tttactaatt gatctatcag ctagtatcgc tgaaatcatg gggtcatcag cccagtttat
      541 tcaagaggat gctatcagac ctcagctgtt aaaagaaagt gatctcatca ttagcgattt
      601 gccagttggt ttttatccta acgacgatat tgctagcagg tatcaggtgg ctagctcaga
      661 tgagcatacc tatgcccatc atttactgat ggagcaagcc ttaaagtacc tgaaaaaaga
      721 tggctttgct attttcttag caccggtaaa tcttttgagc agcccacaaa gtcacctctt
      781 aaaacaatgg ctgaagggct atgctcaggt tgtggccttg attactttgc ctgaggctgt
      841 gtttggaaat ccagctaatg caaaatcgat tattgttctt tgtaagcaat cgaatcgctt
      901 tgcagaaacc tttgtttacc ccattaggga tttgaaatct gttgataatg ttcgtgattt
      961 tatggaaaac ttcaaaaatt ggaaacggga taatgttatt taagagaatt ttttgatata
     1021 atagaaaagc attgcagaaa acgatttcaa gagaggtaaa acatgtcaaa gacaattgca
     1081 attaatgcag gaagctccag cttaaaatgg cagctatatc aaatgccaga ggaaaaggta
     1141 ttagcacagg gaattatcga acgtatcggt ctgacagact caatctctac tgttaaatac
     1201 gatggcaaaa aagaagagca tattcttgat attccagatc atacagaggc tgttaagcgc
     1261 ttgttgaatg atttgattca ttttggcatt attggtacgt atgacgagat cacaggtgtt
     1321 gggcaccgta ttgttgcagg tggtgaatac ttcaaggaat ctgtggttgt tgatgataag
     1381 gttgttgagc aggttgagga gttagcagcc ttggcaccct tgcacaatcc gggggcagca
     1441 gcaggtattc gtgcctttcg taagattttg ccggacatta cgagtgtttg tgtgtttgat
     1501 acttcgtttc ataccacaat gcaaaagcat acctaccttt atccaattcc tcaaaaatat
     1561 tatacagatt ataaggttcg caagtacggg gcgcatggga ctagccataa atatgttgct
     1621 gaggaagcag caaaaatgct gggtcgccct ctagacgaat taaagctcat tacagcccat
     1681 gttggtaatg gtgtgtctat cacagccaat tatcatggtc agtcagtgga tacctctatg
     1741 ggctttacac cgcttgctgg tccgatgatg gggacacgct ctggtgatat tgatcctgct
     1801 attattcctt atttgattgc tcaggatcct gagctaaagg acgcagcaga tgtggtcaat
     1861 atgcttaaca agcaatctgg attaggtggt gtgtctggta tttccagtga tatgcgtgat
     1921 attgaggctg gcttgcaggc taacaatcca gatgccgtct tagcttacaa tatctttatc
     1981 gatcgtatca agaaatttat cggacaatac tttgcggtat taaatggtgc agatgccttg
     2041 gtctttaccg caggtatggg tgagaatgct cccttgatgc gccaagatgt cgtcaatggc
     2101 ttgtcatggt ttggtatgga aattgatcca gagaaaaatg tgtttggtta tcgtggtgat
     2161 atttcaacag cagcttcaaa ggtgaaggtg cttgtcatct caactgatga agagctgtgt
     2221 attgcgcgtg acgttgaacg cttgaaacag actatatcat aatctgataa tatactctta
     2281 gctcagctga tcagttttaa agagtccaaa aaatactttt aattggtacc gacctccaaa
     2341 agttagactt aaaggtttaa cgattggagg tcggtattat tatatagcca aatattctca
     2401 agacaaagac agccaaaaaa tgagacggtc gtaaccgtct caaaaaagtt taatttaatt
     2461 aaaaacattc at
//
LOCUS       DARYLD010000101         2216 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYLD010000101 DARYLD010000000
VERSION     DARYLD010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU651_001884"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TU651_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL0897836.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU651_001885"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TU651_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL0897837.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGDFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          556 c          389 g          645 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagt caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagct
//
LOCUS       DARYLD010000102         2168 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYLD010000102 DARYLD010000000
VERSION     DARYLD010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2168
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..624
                     /locus_tag="TU651_001886"
     CDS             <1..624
                     /locus_tag="TU651_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL0897838.1"
                     /translation="LNASSIVGLDANFIRAKIEHTITSLLEGKVIRARNGAMMIDLSN
                     SKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSHATPKNYTGSALYASIGITSSGDG
                     INSASSGRFCGARFFRYARGYEHTALVDQAEIYGDDIVFSDDFNIDRGFKMRPSLMPK
                     MVDLNKMYQAILALGRCWLHANNTAWTFNSDTTSAIIREYNSYINGL"
     gene            633..1064
                     /locus_tag="TU651_001887"
     CDS             633..1064
                     /locus_tag="TU651_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL0897839.1"
                     /translation="MDLTVQNKDLNTLYSVLDKIKVTNMRVNRGRAKLLAKVEAKLRE
                     YAKDEVDIIDQYAAKNDKGKWLVDDKGNAKLADVTKVTELNDCLDELANEPIVIKGHE
                     YSKRFIDFLEYLAEAEDEFTGAEIVLIDNILEQYEESKKGE"
     gene            1067..1681
                     /locus_tag="TU651_001888"
     CDS             1067..1681
                     /locus_tag="TU651_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL0897840.1"
                     /translation="MARNWKIVGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLS
                     STNDLDVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQDTAKTATTAQTAAGLARA
                     AAERTQKMINLQTIHVLTSGGKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKHED
                     LAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            1694..1984
                     /locus_tag="TU651_001889"
     CDS             1694..1984
                     /locus_tag="TU651_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897841.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            1987..2166
                     /locus_tag="TU651_001890"
     CDS             1987..2166
                     /locus_tag="TU651_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897842.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
BASE COUNT          706 a          404 c          506 g          552 t
ORIGIN      
        1 cttaacgcta gcagcattgt tggcttagac gctaacttta tcagagctaa aattgagcat
       61 acgattacaa gtttgcttga gggtaaagtt atcagagctc gcaacggagc gatgatgatt
      121 gacttgtcaa actctaagat tgactttaac agcaacgcta ccattaactt taataacaaa
      181 gacaacgctt tggtacgtaa agatggcaca cacactgcct ttgtgcactt tagccatgcg
      241 acgcctaaaa actatacagg atctgcgcta tatgcatcta ttggtattac ctcgtcaggt
      301 gacgggatta acagtgcgtc gagcggtcgt ttttgcggcg ctaggttttt taggtatgcg
      361 cgaggttacg agcacacagc gcttgttgac caagctgaga tttacggtga tgacattgtc
      421 tttagcgacg actttaatat tgatcgtggc tttaagatga ggcctagcct aatgccaaaa
      481 atggtcgatc tcaataagat gtatcaggcc attttagctc ttggccgctg ctggctacac
      541 gctaataata cagcgtggac ctttaactca gacactacca gcgcaattat cagagagtat
      601 aactcttaca tcaacggatt ataggagaca acatggattt aacagtacaa aacaaagact
      661 taaatacgct ctatagcgta ctagacaaaa ttaaggttac taatatgaga gtaaatcgcg
      721 gccgcgctaa gctgcttgcc aaagtagagg ctaagctcag agagtatgcc aaagacgagg
      781 ttgatattat cgatcaatac gctgctaaaa acgacaaagg taagtggtta gttgatgaca
      841 aaggcaacgc taaattagct gatgtcacaa aagtaactga gcttaacgac tgtttagacg
      901 agttagccaa cgagcctatc gtcatcaaag gccatgagta ctctaagcga tttatcgact
      961 ttttggagta tctggccgag gccgaagatg agtttacagg ggccgaaatt gtactgattg
     1021 acaacatttt agaacaatac gaagaaagta aaaaaggaga ataattatgg ctagaaattg
     1081 gaaaatcgtc ggcaaatatc cacaaccaaa cgcgctaggg gttattgagg gtacacatgt
     1141 catcatcaca ggtgatgacg gtgcatctat cccgcaaacg ataaaaaaag atctgtcatc
     1201 tacaaatgac ctcgacgtta ttaaaatggt cctcgacgaa tttaaaaaat cagagtatgt
     1261 cgaaattgct atgggcgaag cagtacaaaa agttgatgac ttggaaaagt tgagtcaaga
     1321 tacagctaag acagcaacaa ctgcacaaac agccgctggt ttggccaggg cagctgcaga
     1381 gcgcacacaa aagatgatta acttgcaaac tatccacgtt ttgacaagtg gtggcaagat
     1441 tgagcctgat atctataaag gcatgcttga gcttattgag ccagctaaaa aaggtcagta
     1501 tcaagagcat gatgtcttta ctgtgctaga tgacaagcat gaggacttgg ccggcgaggg
     1561 taaacttgtc tttgtctatg ttaacgaggc ctttgagtac gacaagcaaa ccctcaaaga
     1621 tctggaatca gaggataaag tcacagttat caagtacgct gatttggtta aaggcaaata
     1681 gtgaggtgat tagatgatag attttgtgca aataggcact ttttgtggcg ctgctctgtc
     1741 tatctttggt gtttggggat ttatcgtcaa tccttttaaa aaagcgctgg aggctaacga
     1801 gctagccatg gcccaactca aagactcgat caaggagcta gcctacgagc taaaaaatct
     1861 tgatcgtgat ggagagataa ccaaaaagat tatcgatcgg catgaggagc gtttaggacg
     1921 tgtagaggac gacattattg tcaataaaga gcaaatcaaa acattattta aaaaaggaga
     1981 ctaaaaatgg ataaatggtt taaaaaagta gcaatcaaaa caattaagac aatggcccaa
     2041 accgctgtag gggttattgg atcaagcgca ttgattactg acgtcaactg gcaggtggtg
     2101 gcctcaacag ttattatgtc aggtattgtc tgcgtcttga tgaatgtgtc tgacatcaag
     2161 gaatagca
//
LOCUS       DARYLD010000103         2158 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYLD010000103 DARYLD010000000
VERSION     DARYLD010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2158
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..1297
                     /locus_tag="TU651_001891"
     CDS             <1..1297
                     /locus_tag="TU651_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897843.1"
                     /translation="LIYLKLKGINVIALLKGYRRSYHRSSFFIKTGSIVMVLYLAIVS
                     ILGLTDYLSMRQYIPTWESSKYYANMACAWSWSYEKDDDKFHEIVIPKLNNLWNSLDD
                     SGAILFNAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKNYLHIANLLDKDTNKIEQYKI
                     HENEWIVFVPEDVKITELDKEKIHEDHIFQNIKKQGTIIETYVRLKDNQSVFSFDSGK
                     RIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHPYVKEPSRAYESLKDIIEETE
                     SEPFILYISSVYDDIVSRIDEYKMEASIYVIGLVLSIVILATLLKIDKETYFYNHGQR
                     IDVSRLLGYGFFDIHHKKIIGNIVGYIISIIILFMVIMVTGVISDVGLFIPRDGWSMS
                     KLLISLIIGICGSFICFGIEILQLKKSERSIVLRLKEGC"
     gene            1298..1972
                     /locus_tag="TU651_001892"
     CDS             1298..1972
                     /locus_tag="TU651_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0897844.1"
                     /translation="MQNEKELQITLRNVSKKYGEHSILENISLDIYKGDFVCIFGKSG
                     GGKTTLLNIIGTLENYDSGSVTCFSNRDPIKAPKVGELLRREKIAYLFQNFALVEKMT
                     VEENMMLAAKYNQEKNKKNLIEAALNKMGISDKLKSKVYELSGGEQQRVALARNMIKP
                     FEIMLADEPTGSLDYENKKIVIDTLIRLNDEGKTIVVVSHDKDFEKVAHKNYIIEKSA
                     IREVLR"
     gene            1969..>2158
                     /locus_tag="TU651_001893"
     CDS             1969..>2158
                     /locus_tag="TU651_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0897845.1"
                     /translation="MKRKIALLVPVIVLCICGLFFYMNRNSDDIDVAFTVKNETKEKI
                     DTVGIAMGNKCILNRTNGE"
BASE COUNT          827 a          214 c          430 g          687 t
ORIGIN      
        1 attgatttat ctcaaattaa aaggaattaa tgttattgcc ttattgaaag gttatagaag
       61 aagttatcat agaagttctt tttttataaa aacagggtcg attgttatgg ttctttatct
      121 agcaattgta agtattttag gactcactga ttacttgagt atgagacaat acattccaac
      181 ttgggaaagc tcaaagtatt atgcaaatat ggcttgtgca tggtcttgga gttatgaaaa
      241 agatgatgat aagttccatg aaattgttat tccaaagctg aataacttat ggaatagttt
      301 ggacgatagt ggagcaatat tatttaatgc cccaaacgtt agaaaagagg gaatgaatga
      361 tgatgaggag tatctaaatc aacaaccttt tcaaggtaat tatgcctatg taaataaaaa
      421 ttatttacat attgctaatc tcttagataa agatacgaat aaaatagaac aatataaaat
      481 acatgaaaat gagtggattg tttttgttcc agaagatgtt aaaattactg aacttgacaa
      541 agaaaaaatt cacgaagatc atatttttca aaatataaaa aaacaaggta caattataga
      601 aacatatgta aggctgaaag ataatcaaag tgtattttct tttgatagtg gcaaaagaat
      661 tgatgaagca aacttgaaaa attatgtttt ggtagcagta aatgggaaag aattactccc
      721 agatcacgga atcaaactat catctttagt aaatgggcag ctacatccat atgttaaaga
      781 gcctagtagg gcatacgaga gtttgaagga cataattgaa gaaacagaat ctgagccgtt
      841 tatactctat atcagctcag tttacgatga tatagtttca agaatagacg aatataagat
      901 ggaggcaagt atatatgtta ttggtctcgt cttatctatt gttattttag caacgttatt
      961 aaaaatagat aaagaaacat atttttataa tcatggacaa cgaatagatg tttctaggtt
     1021 gttgggatat ggattttttg atatacatca taagaaaatt attggaaata tcgttggtta
     1081 tatcataagt attattattt tatttatggt tattatggta acaggagtaa taagcgatgt
     1141 tggactgttt ataccaagag atggttggag tatgtctaaa cttttgatta gtttaataat
     1201 aggtatttgt ggaagcttta tatgttttgg catagaaatt ttacaactaa agaaaagtga
     1261 aagaagcatt gtacttaggt taaaggaggg ttgttaaatg caaaatgaaa aggaattgca
     1321 aataacctta agaaatgtct ctaagaaata tggagaacac agtattttgg aaaatattag
     1381 tttggatatt tataaaggag attttgtttg tatctttggg aaaagtggag gaggaaaaac
     1441 aacactttta aatataattg ggacattaga aaattatgat agtggtagtg taacctgttt
     1501 ttcaaatcga gatcctataa aagctcctaa agtaggagag ctattacgca gagaaaaaat
     1561 tgcttattta tttcaaaatt ttgctttggt ggaaaaaatg acggttgagg aaaatatgat
     1621 gcttgctgca aaatacaatc aagaaaaaaa taagaaaaat cttatagaag ctgccttgaa
     1681 taaaatgggc atttcagaca aattaaaatc gaaggtttat gaactttcag gtggagaaca
     1741 gcaaagggta gctcttgcaa gaaatatgat aaaaccgttt gaaattatgt tggcggatga
     1801 accgacaggt tctcttgatt atgagaataa aaaaattgta atcgatacac ttattagatt
     1861 aaatgatgaa ggtaagacaa tcgtagttgt aagtcatgat aaggattttg aaaaagtagc
     1921 acataagaat tatattattg aaaagtcagc tataagggag gtgttgagat gaaaaggaag
     1981 attgctttat tagtaccggt tatagtactg tgtatttgtg gtttattctt ttacatgaac
     2041 agaaatagtg atgatattga tgttgcattt acagtaaaaa atgaaacaaa agaaaaaata
     2101 gatacagtgg gtattgcgat gggaaataaa tgtattttga atagaacaaa tggagaaa
//
LOCUS       DARYLD010000104         2036 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYLD010000104 DARYLD010000000
VERSION     DARYLD010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2036
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            31..432
                     /locus_tag="TU651_001894"
     CDS             31..432
                     /locus_tag="TU651_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003033322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL0897846.1"
                     /translation="MAVKRKYIYVKGQKIYVPDEVYRAYKKGLNHETHLKRLDRKHGV
                     FRFGDFNTSIVDIADNTVDVEKIIETKMLIEDLYYALDSLNDEERKLIEALYFDDKTL
                     TEVAKQRDTNPMKISRLRNKILEKLRKFLDK"
     gene            888..1055
                     /locus_tag="TU651_001895"
     CDS             888..1055
                     /locus_tag="TU651_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL0897847.1"
                     /translation="MCEEHNIDIKMEIDKKDKQTINQIDGWNIEVKFNENGLSLENLV
                     EEYIKEKFSVY"
     gene            1154..>2036
                     /locus_tag="TU651_001896"
     CDS             1154..>2036
                     /locus_tag="TU651_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019115678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL0897848.1"
                     /translation="MFKDSVNKENIAVMYLRLSKEDGEKTESNSISNQREMINSYAKK
                     NQFIIIKEYVDDGYSGATFDRPNFKEMINDAYDKKFDTIIVKDLSRFGRDYIEAGKYI
                     QRIFPENGIRFISVNDNYDSKSADMNDTHLILPIKNFINDSYCRDISNKVKSSQKIKR
                     EKGDFISAFAPYGYKKSDENKNKLVVDEQAAPNIKNIFDMKLLGYSSKAIADELNHLG
                     VLTPRKYKESQGFKCNGFQNIKGGNWSAKSVNRIIENEVYIGNTLQGKSVTLNYKNKK
                     QIEREKEDWIRVENTHDA"
BASE COUNT          837 a          220 c          396 g          583 t
ORIGIN      
        1 aaatttttga taaaaaggag ggctttacaa atggcagtta aaagaaaata tatctatgta
       61 aaaggtcaaa agatttatgt acctgacgaa gtgtatagag catataaaaa agggcttaat
      121 catgaaactc atttaaagag attggataga aagcatggcg tatttcgttt tggagacttt
      181 aacacaagta ttgtagatat tgcagataat actgttgatg ttgaaaaaat cattgaaaca
      241 aaaatgctga tagaagatct gtattatgca ttagacagtt taaatgatga agagagaaaa
      301 ctaattgaag cactatattt tgatgataaa actctcacag aagttgcaaa acaaagagac
      361 acaaatccaa tgaaaatcag tagattaaga aataagattt tagaaaagct gagaaaattt
      421 ttggataagt aaattaagta gagggcaggg aaacatctct gtcctctatt tttgaaaatt
      481 tttcaaaaat agtgttaaaa gttgtcctga aagtaaggtt tatatataga gggactttta
      541 ttacctcgtt atatatagat ttgatctttg acaactgaat agaccaagac aagactttaa
      601 ccagtagtgg agcaatttat aaacttacgc caagataaac ctgctaagtt aaattgattt
      661 aaatgaatac ctacatttgt agaggatata aggtttggag cgataaataa gtctgtataa
      721 aaagagggtg gcaactcttg tgcgatgata ctaatgggga taatgatact tctacagttg
      781 aagccggctc atcttgaaaa gaggcggagg tgaaattcct atgtagcagc caatgcactt
      841 gtcaatgtca taaaacttaa aaatattgaa gataaggaga agatattatg tgtgaagaac
      901 ataatataga tattaagatg gaaatagata aaaaagataa acagacaata aatcaaattg
      961 atggttggaa tatcgaagtt aaatttaatg aaaatggatt gagcttagaa aatttagtag
     1021 aggaatacat caaagaaaaa ttttctgtct attaggggct gacaaaaaat ataaggagcg
     1081 ttataatatt tttgtggaag cctaaccttg gttcgattta ttgtatgtaa attgaattta
     1141 aggaggcttt tttatgttta aagacagtgt aaataaagaa aatattgcag ttatgtattt
     1201 gaggctttca aaagaagatg gagaaaaaac agaaagtaat tctatatcca accaaagaga
     1261 gatgataaat tcttacgcaa agaaaaatca atttataatt atcaaagagt atgttgatga
     1321 cggatattca ggagcaactt ttgatcgtcc taattttaaa gaaatgataa atgatgctta
     1381 tgataagaaa tttgatacga ttattgtaaa agacctatca agatttggaa gagattatat
     1441 agaagcaggg aaatatatac aaagaatatt tccggaaaac gggataagat ttatatctgt
     1501 aaatgacaac tatgatagta aaagtgcgga tatgaatgat acacatctaa tactccctat
     1561 aaaaaacttt atcaacgaca gctattgccg agatatttcc aataaagtaa agagttctca
     1621 gaagataaaa agagaaaaag gggattttat cagtgctttt gcaccttatg gatataaaaa
     1681 atctgatgag aataaaaata agttggtggt tgatgaacaa gctgctccta acatcaaaaa
     1741 tatatttgat atgaagctct tgggatattc ctcaaaggca atcgcagatg aattaaatca
     1801 cttaggtgtt ttgactccga ggaaatataa agaaagtcaa ggctttaagt gtaatggatt
     1861 tcaaaatata aaaggtggta attggtcagc aaagtcagta aacagaatta tagaaaatga
     1921 agtatatatt gggaacacct tgcaaggcaa aagtgttacc ttaaactata aaaataaaaa
     1981 acagatagaa agagagaaag aagattggat aagagtagaa aatactcatg atgcaa
//
LOCUS       DARYLD010000105         2032 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYLD010000105 DARYLD010000000
VERSION     DARYLD010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2032
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..196
                     /locus_tag="TU651_001897"
     CDS             <1..196
                     /locus_tag="TU651_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HEL0897849.1"
                     /translation="TAMKSLKNSKLQTLSIKNLSDKYMLLEQEKTTLMGEYSSQNSML
                     RKLQQAKKNTDLYLDNSLEK"
     gene            complement(306..791)
                     /locus_tag="TU651_001898"
     CDS             complement(306..791)
                     /locus_tag="TU651_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL0897850.1"
                     /translation="MIGLVILFIALIILYLGVILFAGATFVKISLFALDKLVVFIASW
                     YYTHHYFSVKFSSGYAIYFWDILAAILVVIIYSILFQFIHKKFRVLGKILNLAISFFS
                     SMIVYCLLVNGFITTEKSYFLPLLNNSFMNQVVNYIIIAIISLVVWKRREDYLVETHD
                     K"
     gene            complement(949..1908)
                     /locus_tag="TU651_001899"
     CDS             complement(949..1908)
                     /locus_tag="TU651_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL0897851.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT          648 a          392 c          219 g          773 t
ORIGIN      
        1 aacagctatg aaaagtctta aaaattcaaa gcttcaaaca ttgagcatta aaaatttatc
       61 tgataaatat atgcttttag aacaagaaaa aactacactt atgggagaat attcctctca
      121 aaactctatg cttcgcaagc tgcaacaagc aaagaaaaat acagatttat accttgataa
      181 cagccttgaa aaataaaaaa aagaaggaga ttatccctac ccatatttca ggtaagaata
      241 atctccttac ttgctctcaa attgataaaa gtatattttc tacaatattt cacaataata
      301 ttttcttatt tgtcgtgtgt ttctacaaga tagtcctctc ttcttttcca cacaaccaaa
      361 gaaataatag cgattataat ataattgacc acttgattca taaagctgtt gtttaaaagt
      421 ggcagaaaat aggatttttc agttgtaata aatccattca ccaggaggca atatacaatc
      481 atagagctaa aaaatgaaat agctaaattt aagattttcc ctaacactct aaattttttg
      541 tgtatgaact gaaatagaat agaatatatt attactacca atattgctgc cagaatatcc
      601 caaaaatata tagcatatcc ggatgagaat ttcactgaaa agtagtggtg ggtatagtac
      661 cagcttgcta taaataccac aagtttatcc agtgcaaaca ggctaatttt tacaaatgtt
      721 gctcctgcaa atagaatgac tcccaaatat agtataatta aggctataaa aagaataacc
      781 aatccaatca tatcattcac ctctctatca aaataatctt ctttttctta taatataacg
      841 ctcctgttat agtttatcaa acctttattt ttccatttct aataaaaaaa caaagaaaaa
      901 tagtggataa acagccctat cagctattta cccactattt ttataatttt atctctctat
      961 atttttatct tttttgacac tgacctgttc ctttgatttt tcgcctgcct tttccttata
     1021 ctcttttaac ttgccaagtg ctgacggttt ctttacatcc tttgcatttt gatttgtttt
     1081 gctctgttct ttggctttta acagctttgc agaataaact ttaagagatg tatattcctt
     1141 tccgtccttt ccctgactga ttttttcttt tccgaataca tgaacaaaat ctcctttttt
     1201 caaattttct acactactta ccttatcgtt ataggctaaa cagttggtat attttacatt
     1261 tccctccttg tcattttcag caactgcaaa acttgcaaca gtaaaatctc taccatcttt
     1321 cgatgtcaaa tttttaatgt ctatatctga agcaatattg ccattgatat ttacagtatt
     1381 tgctttttcc ttattttcat ttgacttctc actcgtagta ttattgtcct cctttacatt
     1441 ttcctcatcg gataaaacac tattcttatc ctgtatttcg ctttctaaat caggtgcttc
     1501 aatctcattt tcatctatat aatgataaaa tttttcatca accaaaccca taattttatc
     1561 attcatataa ttatcataag cagcatcaag agtatcctca ttttctattc ctgtttcaag
     1621 agacagaatt cctttgacaa aatcgctatg attatactct gctaaaaaag ataaggtctc
     1681 tttcatcgtt tcaaaattat tgttttgtat atcggaaatg ctttttaaat catttgcata
     1741 tcgcccatta tcccattcaa attttccgct ttccttgttt tctttaatcc ctgttgcaag
     1801 tacaaactga gtacctgaaa acagtaccgc ctgattatct ttcacatcca aaactgttgt
     1861 gttttcactt aatgctgttt ttacaatatc gcctttttct aatttcatat tttttacctc
     1921 ctgtactttt acttgtatgt tttcttctaa ttctttatca ataatatttt taatactttc
     1981 ttttatcgct tctaaatatc ccttcctttt caaactatca taaaaatcat ta
//
LOCUS       DARYLD010000106         1891 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYLD010000106 DARYLD010000000
VERSION     DARYLD010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1891
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..487)
                     /gene="mreD"
                     /locus_tag="TU651_001900"
     CDS             complement(<1..487)
                     /gene="mreD"
                     /locus_tag="TU651_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL0897852.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LI"
     gene            complement(490..1305)
                     /locus_tag="TU651_001901"
     CDS             complement(490..1305)
                     /locus_tag="TU651_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL0897853.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            complement(1364..1451)
                     /locus_tag="TU651_001902"
     tRNA            complement(1364..1451)
                     /locus_tag="TU651_001902"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1415..1417),aa:Ser,seq:gct)
     gene            complement(1461..1534)
                     /locus_tag="TU651_001903"
     tRNA            complement(1461..1534)
                     /locus_tag="TU651_001903"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1498..1500),aa:Ile,seq:gat)
     gene            complement(1564..1634)
                     /locus_tag="TU651_001904"
     tRNA            complement(1564..1634)
                     /locus_tag="TU651_001904"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1600..1602),aa:Gly,seq:tcc)
     gene            complement(1640..1712)
                     /locus_tag="TU651_001905"
     tRNA            complement(1640..1712)
                     /locus_tag="TU651_001905"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1677..1679),aa:Phe,seq:gaa)
     gene            complement(1737..1810)
                     /locus_tag="TU651_001906"
     tRNA            complement(1737..1810)
                     /locus_tag="TU651_001906"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1774..1776),aa:Met,seq:cat)
BASE COUNT          670 a          414 c          317 g          490 t
ORIGIN      
        1 atattaattt tctaaagcaa aacaaaataa ggagattgac gattaaagtc ggagcaagct
       61 gaaacgtcat tacataagga aaagtcatat cagttaactg atagctgttt gccaaaataa
      121 agcttgatac atctacaaga aacatataaa gagtaaagaa aaggaaaaat tgtagctgac
      181 taatggaacc agaaaagaac cttaatagcc ctagaacgat cattgttcca aaaggcaagg
      241 caagagacaa aatccctata tgatcaaaat aataataatc aaacaataat cctaaaagaa
      301 gagagaagaa acaaataact cccttagatc taaacgctac cataaggatc aggaaaaaca
      361 gtaaaaagag gtgtgatact accgagtaac cctcaggtaa cattgagctg atcaggtctg
      421 acacgtgtgc atcaacaaaa aataaaagaa aaggcaaaag gactaatagc tctgaagatt
      481 ttttcatatt cactcttttc caacaacaag aacatagtca agattatcag tatcagcata
      541 caattttata aaaatacgac gctttagctt atcagcagca tttttaaagc ccgtaacctt
      601 tccaacagga atatctgcca cagtctcacc atctaatcca cttgtataaa ccttagcatc
      661 taatgatatt gagtcattag aattaaattc gctggcaacc attgttttac tttctgattt
      721 aaatgccttt aaattgccat aaatcacctt atccttatct acaattttaa tcggcaactc
      781 aatattcttc ccagatgtta acaattcaac atgagcagat gactggctaa cagctgtaac
      841 acgaccaata agtccaagct ctgaagtaac caaagacttc tccttaattt cccttttgcc
      901 gctatcaatg accagcgatt tattccagct ataaggattt cttgatatca ttctggcagc
      961 aaattgatta tcagtaccat aatccaaccc taacagttcc ttgagctctc gattttcaga
     1021 ttttagcttg tcaacctgta actgatccaa tttataggac ctaagttcct tttttaaatg
     1081 cttattttca gaaaaagcag acatcaagct atctaattcc tttgcaccct cctttataac
     1141 agcaaaaggc ttagacatta tagcatcaat ttttgtaacg ggatttcgga taatcattga
     1201 taaatatgga gaaatagcta ctctaaaaag aagaaccaag gtcaaagcca gtaaagctaa
     1261 tgatgttaac caaaaaaaga gacgagatag gttaagcttt ttcaataaaa tcacctctaa
     1321 aaataaaaaa acgattatca gtatgataat cacctttaca atacggagaa taagggattc
     1381 gaacccttgc gccagttacc cgacctaacg atttagcaaa ccgtcctctt cagcctcttg
     1441 agtaattctc caaataatga tgggcacgag tggactcgaa ccaccgacct cacgcttatc
     1501 aggcgtgcgc tctaaccacc tgagctacgc gcccaagcac actatagctt gggaaaacta
     1561 taaagcgggt gacgagaatc gaactcgcga caacagcttg gaaggctgta gttttaccac
     1621 taaactacac ccgctaaaat ggcgcgagac ggaatcgaac cgccgacaca tggagcttca
     1681 atccattgct ctaccaactg agctaccgag ccaaccagca tatatctttt atataattgc
     1741 gggagcagga tttgaaccta cgaccttcgg gttatgagcc cgacgagcta cctaactgct
     1801 ccatcccgcg ataatcttta aaggaggatg tgggattcga acccacgcac gctgttacac
     1861 gcctgacggt tttcaagacc gttcccttca g
//
LOCUS       DARYLD010000107         1865 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYLD010000107 DARYLD010000000
VERSION     DARYLD010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1865
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..886
                     /locus_tag="TU651_001907"
     CDS             <1..886
                     /locus_tag="TU651_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0897854.1"
                     /translation="LDEPTANIDKKTIIKIGKIIEKLKKRGHTVIICEHRLYFLKDLV
                     DRVFYVDQGEIKRTFSGDEFFRLENKERISMGLRTLEVPKLKNMLTYDEICDNTLKIK
                     NLSCCYGEKIVFKNLNLSIRSGEILGIIGNNGVGKTTLLRCIAGLHKETKGEITLNGD
                     VISGKKRQRLSAMVMQDVNYQLFADSLVEECCLGNNCDNIQIDKVLGELKLIESKKSH
                     PMILSGGQKQRLVVANAILSDKKILIFDEPTSGLDYEGMLAVSNELKKLSEKNYYIFV
                     VSHDIEFINEICDRVYEF"
     gene            909..>1865
                     /locus_tag="TU651_001908"
     CDS             909..>1865
                     /locus_tag="TU651_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897855.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNKYMNSTIVEYISGIEVIKTFNQD
                     SNSYKKYKDAVNLYKDHTLNWFKSTWSIMNFASSILPSTFLGTLPVGMILYLNGTLTP
                     AEFCICLMLSLGIVIPLTQFTNYVNLLKSIEYAVKDINEILCI"
BASE COUNT          710 a          194 c          345 g          616 t
ORIGIN      
        1 tttagatgaa ccaacagcaa atattgataa aaaaacaatt ataaaaatag gaaaaatcat
       61 agaaaagcta aagaaaagag gacatacagt aattatatgt gaacatagac tttatttttt
      121 aaaggatttg gttgatagag tattttatgt tgatcaagga gaaattaaaa gaactttttc
      181 aggggatgag ttttttagat tagaaaataa agaaagaata tctatgggtc ttagaacttt
      241 agaggtaccg aagttaaaaa atatgcttac ttatgatgaa atatgtgata atacgttaaa
      301 aattaagaat ttgtcttgtt gttatggaga aaaaatagtt tttaaaaatt taaatctaag
      361 cataagatct ggagaaatat taggaattat aggaaataac ggtgttggaa agactacact
      421 tcttcgatgt attgcaggat tacataaaga aacaaaagga gaaattacat taaatggtga
      481 tgttataagt ggcaaaaaaa gacaaaggct atctgcaatg gttatgcaag atgtgaatta
      541 tcagttattt gcagatagct tagtagaaga atgttgctta ggaaataact gtgataatat
      601 acaaattgat aaggttttgg gtgaactaaa attaattgag tcaaaaaaat cacatcctat
      661 gatactttcc ggtggacaaa aacaaaggtt agtagttgca aatgcgattt tatctgataa
      721 gaaaatatta atttttgatg aaccgacatc aggattggat tatgaaggta tgcttgcagt
      781 gtctaatgaa ctaaagaagt tgagtgaaaa aaattactat atttttgtgg tttcacacga
      841 tatagaattt ataaatgaaa tatgtgatag agtttatgaa ttttagataa aggaggtgga
      901 gaagttacat gagcaacaaa aactggataa atactatatt agattttgct tcagattgta
      961 aaggaaagtt gattttatca gtagttatgg ctagtatagg agtgttcttt agcattatac
     1021 cttattggtc agtatataaa cttatggcag tctttataga acaaaaagca actggagaag
     1081 atgtattgta ttatggagcg attggtatta ttgcatattt tatcagatat atttgccatg
     1141 gagtatcaac aatattatct catatatccg cttacacaat cttaagaaat ataagagaaa
     1201 atttaggtga aaaattgctc agtatttcta tgggaaatgc gtcaaaaaag acaataggag
     1261 aatataagtc aattattgta gacaaagttg aaacaattga gatgcctcta gcacatatca
     1321 taccagagtg tgttgctgca ttgcttttat cactaggtat tgcaatattt atggtcttca
     1381 taagttggga gatggctctt gcgatgttta ttacagtgcc ttttgctttg atggcatata
     1441 aaaaactaat gggtaatttt aatcagcttt atgaagctca aatgaaatct aacaagtata
     1501 tgaattctac aatagtagaa tatattagtg gtatagaagt tataaaaact tttaatcagg
     1561 atagtaattc atataaaaaa tataaagatg cagtaaattt atacaaagat catacattga
     1621 attggtttaa atcaacttgg agtattatga attttgcaag ttctattttg ccatcaacat
     1681 ttttgggaac attacctgtg ggtatgattc tatatttaaa cggaacactg acacctgctg
     1741 aattttgcat atgtctaatg ctttctcttg gaatagtaat tcctctcact caatttacaa
     1801 attatgtcaa tctgttaaaa agtatagagt acgctgtaaa agatataaat gagattctat
     1861 gtatt
//
LOCUS       DARYLD010000108         1780 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYLD010000108 DARYLD010000000
VERSION     DARYLD010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1780
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(207..1721)
                     /locus_tag="TU651_001909"
     CDS             complement(207..1721)
                     /locus_tag="TU651_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL0897856.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          610 a          365 c          292 g          513 t
ORIGIN      
        1 aaatccactt gaaaggctta tcacaagtgg atttttcaga aatattgtac caaataggca
       61 cgagctattg attgctgcta tttagcatag gtgttatcac gatcagcagt aagccaatca
      121 aaacaggtat cgctaaagca aatcctcaca aaaaatggtc caaagaaaaa cctagcagcc
      181 ttataccact tgcttagcaa aaaaacttac tctaccctat ctccaatcaa gagctgctct
      241 aaaagctgct cgtaatgctt acgatgaaag ttcagaattg attttaccac tgtttttccc
      301 tgctccttaa tgtaatccat gctcatacca attaagacgc tcttatctgg aaatacctgc
      361 tgctcctcaa gaaaaggcaa aatattatca ctcgtaatca caaaatcagg agcctgctca
      421 taattttcca gactatctgt tagcatgttg atacgagtaa tattaacctt ataagaagga
      481 atacttgaga taacaaagta agacaagaca tcacctaatg ctctcttgtt ttcaacgatg
      541 atgacctcta caggcggcaa ggacagctca agcatctgct ccaaatgaag gcacataaaa
      601 tgcaggtgcc ctggtgagag cgtttctgac tggtagctaa ccatcagcca gtccttgatt
      661 tgctcctcaa ccttttctag cagcagctga ctgccttgat acctctttga atagtaatcc
      721 tgaaagctaa tcaaatcatg caattgaaag agacatcttc tgaaaaaggg aagcaaaaaa
      781 tacatctgat cccttaaatg aagctgacga ccaaacaaca tttccaagcg attaacaagc
      841 tccttataca gcggatcttc ttctaagata ttgtagacaa gacgtaattg cttgtcattc
      901 caataatgca taagaaaaga actatcaact gtaagataaa ccaagtaaag ataatctaag
      961 tcaccagaat taaacacaac ctgagtacgt gtctcaattt cttgcttagc atagcaactg
     1021 atttgctcaa aaatagataa ttcttttaaa cgatcaaata aagtaagctg tggtaaggat
     1081 acatcataat tctgcctctt ccaagacagc atgagtaaaa tatcaaaaag ataaaatttc
     1141 ttgtccaaga aaacagtggg ctttaaccgc gtaggggtta aaaaaataaa ggcatgaata
     1201 atttccatat ccttaggtgt catctcataa acagcaaacc catactcctt atgaagcatg
     1261 gcaattaagt agcgaatccg gtactcatcc cctataaccc ggtaatcatc gatatccaaa
     1321 tgaatggatt gcaggtagcc ctttagctta ttgacaagat gataggcctt tgatttggaa
     1381 ataaactgtc ttctgatgaa agttgtcaga cactttgtcc tgtaattatc cgtcaacaga
     1441 aacttcaaca ttttaagcgt atcagatgat gcataaatac tgtgaaaata cttctccttg
     1501 ttattaggat caaactcaca ggtaatgcct gacttcaata cagtaataga caggtctttg
     1561 tcaaatagtg cattaatctg attaaggtat tccttagcct ttcgaggggt tattgacgtc
     1621 tgcgagcaca atgaatcaag tgtaatctct ttttctgtca ataagacagc caatattagt
     1681 tttcgctcaa caatatctct ttctaaatag taatctaaca aaataatctc tctccttatt
     1741 agtttgtatg accatataca ttttagttga taggatttaa
//
LOCUS       DARYLD010000109         1667 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYLD010000109 DARYLD010000000
VERSION     DARYLD010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1667
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(584..1450)
                     /locus_tag="TU651_001910"
     CDS             complement(584..1450)
                     /locus_tag="TU651_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL0897857.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          516 a          333 c          235 g          583 t
ORIGIN      
        1 aggtaaaaca taatcattcg tctctacata tctaaagctt gtcagatcca tatgcttcac
       61 catgtaccag ctgaataaat gggtacttct ctggatgctc catgattgtc ttaactttct
      121 tttccacgta ggcttcaaag cttttttcaa agctacttga acactcacga gaatcttctt
      181 tatagataca tttttaagta atcattggtt ttctcatagc aatacatctc ctcagtctta
      241 ttagtataaa actaaaaacg ctcacattaa caggtctttt tgagcgtttt tagtaggact
      301 agttactaaa ttatggtttg tagattggac atttccaagt cacaacaaag cctttcactg
      361 gcgcaaagca tctactagcc tcgtatgcaa attgagtcat gtttgtgatc tcctttcatt
      421 cttgatgagt ctagtgtatc atcaaaaacc gtaccaaagc taaactgttc atatgttcaa
      481 atcatggttt tgacattaat caaaaaacag tagctcaaaa agccactgtt tgctactagc
      541 taagcatcta aaccattttg cttatcaatg ctttaagttg catttattca acttccttta
      601 accatttctc taaactatct gaataatagg ctgcactttc atcacaattt aatgccttta
      661 agatgtgtat ggcgtcattt atttgcttta agcctagttc cttttcccct ttacaatata
      721 ggtgctgacc atcagcaatc atataaacaa ttcttaagta ggtgtcattt tcttcaaaaa
      781 aatgattgtt aatcatttta tcaaaatatg cagctatacc tagccttttt tcctgagtag
      841 ctttaaacag cccatttaat aaaatgctgt gcactaaatt tcgatgctgc caaagctcct
      901 caaaaaagtc tactcttcct agcatttctc gagtataccg caaatacaca tccaaggata
      961 ataagggaga aatatctgaa aataattgta attcgtatat tccccaaatc tccactgaaa
     1021 acaaataatc atataaaaag ctttgctcat ctggagtcat tttgatattc tcgtctaaaa
     1081 agagcatttg gcttttaatc atcaaagcat ttaaaaaata gatatccttt ttgtataaat
     1141 gatactgctc cagctctttt gtatacaatt gatgtaagct ggacaggtct ttttttgata
     1201 tggcctccca gatctcttgc tttaggacag catatgggga aggcttaaag ccatttgcta
     1261 gatagataaa ttcattgagc tctgtccgaa tattgctaag tccaaccaat agctttgaga
     1321 ttgttatatc ggattcacca ttttcaaatc tgcttaacat cgagtgagaa aagtcatctc
     1381 ccgtcgcttc ctttaacgat atgtgtcgcg atgtccgcag taatttaaac atttctccca
     1441 tatattgcat atcaatacct cttcaatctt tcattttagt atagtatata accttaaaaa
     1501 tgtaaatcca gtcttgattg cataaacctt taattcaacg tttgatgcta ctaaatatcc
     1561 tatttttctg aagtagatcc tcatctttat gctataagca cttgctgcgt tttagaaaat
     1621 gggctaaatc agctatactc ctttttaata acaaaaaagc cttattt
//
LOCUS       DARYLD010000110         1627 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYLD010000110 DARYLD010000000
VERSION     DARYLD010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1627
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..230
                     /locus_tag="TU651_001911"
     CDS             <1..230
                     /locus_tag="TU651_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897858.1"
                     /translation="LGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLL
                     CLTIVGIPFARQSLKLAKISLFPFGAIIYDI"
     gene            249..893
                     /locus_tag="TU651_001912"
     CDS             249..893
                     /locus_tag="TU651_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL0897859.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(1324..1491)
                     /locus_tag="TU651_001913"
                     /pseudo
     CDS             complement(1324..1491)
                     /locus_tag="TU651_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          475 a          340 c          288 g          524 t
ORIGIN      
        1 ctttgggtct ttttcctttt ggaaaagcca tcgaaattgg ccaaggagca ggcagcctgc
       61 tgctcaatat catctggatt gtctgctgtg gctggagctt agcgatcatg catttgactt
      121 ctgcccttct cttgtgcctc acgattgttg gcattccatt tgcccggcaa tctctaaaat
      181 tggccaagat tagcctcttt ccttttggag ccatcattta tgacatttaa ttaggaagca
      241 aaagacttat gaaattgtat tttgtcagac atggtaaaac cttgtggaac ctagagggcc
      301 gttttcaggg agctaacgga gattcgccct tgcttgaaag ctctaaggac gatttgcgcc
      361 agctagcaag agagctgtgg gacatttctt ttgatgcgat ctactccagc gacctaaaaa
      421 gagctgttga tactgctcgc attattgtgg acgaagctaa ctgcaagact gatattagtt
      481 ataccaagca gctgagagaa tggaacctag gcaccctgga aggaaccaaa atagcaactg
      541 tatccgccat ctaccccagt cagatgtcag ccttttatca caatttagcc aaattcaagc
      601 ccagtcaatt taaggctgaa tccctttatg aaagcacaca aaggctttat cagctcatta
      661 aaagtttgga agataaggcc tatcagcagg ttttaatggt aggacatggc gcccatttga
      721 cagcttctat tcgtgctctt ttaggctttg agccaggtat gcttcgggca cagggaggac
      781 tggataatgc cagcctaacc gttatagaaa ccttggattt caaacacttt cattgtctaa
      841 ggtggaatga tacatcattt ttacaaaaaa agactactag attaacaccc tagtagctct
      901 taagcacaaa gctccaagac agctaaactg tactccattg gttagagaac acatctcatt
      961 ttttgaggga cgctttatta gctgtaggaa gttatgaaaa gctaaataca cgagaggact
     1021 aaattggaca agctcaaaag tttgacaatg tatttcaaaa aaggattgaa ttctgtatcg
     1081 aacaggactc agtccttttt atcatttatc aagccgacca aggctttcaa ccacgacaaa
     1141 cgcgcaaaac agttatttcc tgatgatagt agagactaca gcagatattt tcaatgattt
     1201 tcttgtagta acatctatac aaaacaatac agctcattga aatataggaa cattaaaatt
     1261 cagaaagatt tcttttcttg ctaaaaatct ttcatccatt tcaaactggt tttcatttgt
     1321 cctctccttt ttcagttctg ctttttctcc ataagctgca cagttgatgt actccttgcc
     1381 tttaccgtac ttctttacaa atgtaaaatt tacaacttat acttcttctc cttctctttc
     1441 aaaacttgag taaattgatt ctgctactaa atttgcgtta atattaatca ttttttatcc
     1501 ataatttttc tcctttttta atttaaaatt cccattaaaa aagcgactgg actttttcca
     1561 atcgctgata cttctactat tttattttta tttcggtaga acttctaatc cttatcatct
     1621 atatcct
//
LOCUS       DARYLD010000111         1608 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYLD010000111 DARYLD010000000
VERSION     DARYLD010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            91..648
                     /gene="efp"
                     /locus_tag="TU651_001914"
     CDS             91..648
                     /gene="efp"
                     /locus_tag="TU651_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL0897860.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            691..1080
                     /locus_tag="TU651_001915"
     CDS             691..1080
                     /locus_tag="TU651_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL0897861.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1073..1525
                     /gene="nusB"
                     /locus_tag="TU651_001916"
     CDS             1073..1525
                     /gene="nusB"
                     /locus_tag="TU651_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL0897862.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          483 a          289 c          375 g          461 t
ORIGIN      
        1 aagggctgat aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac
       61 gataactatt ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt
      121 atgacgtttg aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca
      181 ggtaagggaa acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc
      241 gacacaacct atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct
      301 caataccttt acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag
      361 tatgagattc cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat
      421 gtgaaaatcc agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag
      481 ttgactgtta cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag
      541 cctgcaaccc ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa
      601 aagctaatca tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg
      661 aattagtcta agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt
      721 atttcgccac gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt
      781 cactcgcttc acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc
      841 gtctatcttc agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa
      901 tatggtgtaa aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt
      961 tatgacatgg ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct
     1021 gaaaagacac caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa
     1081 gcattttcaa cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat
     1141 ggagatgggc ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc
     1201 agctgatgac aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt
     1261 tatggatcat aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc
     1321 cattgagcgc ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac
     1381 cctgtttgag gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa
     1441 atattctgat gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga
     1501 tgagtcagct gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc
     1561 tatagggctt tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYLD010000112         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYLD010000112 DARYLD010000000
VERSION     DARYLD010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            71..1468
                     /locus_tag="TU651_001917"
     CDS             71..1468
                     /locus_tag="TU651_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL0897863.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYLD010000113         1478 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYLD010000113 DARYLD010000000
VERSION     DARYLD010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1478
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            59..427
                     /locus_tag="TU651_001918"
     CDS             59..427
                     /locus_tag="TU651_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL0897864.1"
                     /translation="MANRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILE
                     KDIFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIY
                     FLRKKLYELGNFGTSGTEEI"
     gene            427..>1478
                     /locus_tag="TU651_001919"
     CDS             427..>1478
                     /locus_tag="TU651_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL0897865.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEKRSYKKP
                     DTIVDMKNNEKVKSSKGYEVWAGKHNMKTMASALNEMRKSGINSYEELDLKLKKVASD
                     RQQLLDHIKQIEKEMKS"
BASE COUNT          607 a          208 c          269 g          394 t
ORIGIN      
        1 ttttacaggt tttttctttt gtaaactttt aatacatcta tgaattggag gttatactat
       61 ggcaaacaga acaagaaata atggaatata ccttatgctt tctgatgatg aacttgaaat
      121 tttgaataaa aaatatgaac tgtccggttg taaaagttta agacagttta ttatgaagtg
      181 catccttgaa aaagatattt ttgtactgga tatgaaagtg tttaaggaga tgtctacaaa
      241 tatcggaagg attacaggta gcatcaatca gattgcaaaa agggtaaatt caactgctgt
      301 aatttacaaa gatgacatca atgatttgaa aaagctcttg gaaaaacaag gaaaagacat
      361 ctactttctt cgtaaaaagc tatatgaatt agggaatttt ggaacaagtg gtacggagga
      421 aatctaatgg cagttacaaa aattcatccg atagaaaaaa cactttatct agcattagac
      481 tatattatga atgaagataa aaccgatgaa aaaatcctta tctcctcttt tggctgcaat
      541 cccaaaacag cccatcttga atttgaacat acaaaaaaag aatgtaattc caaagcaaaa
      601 atcttggcaa ggcatctaat tcaagccttc gctccaggag aaactacacc tgagcaggca
      661 caccaaatcg gactggatct atgtgagaga gtcttgaggg gaaagtatga atatgtcctt
      721 acaacacata tcgacaaggg gcatctacac aatcatattc tgtttaacaa tgtcagcttt
      781 gaaacaggaa aggcatatca aagtaataag agaagttatc atcaaatccg aacggtcagt
      841 gatgatttat gtagagaaaa tggcttgtca gttattgatg aaaactacaa aaaatttaaa
      901 aacagatact ctacaaatgg taaaacctat atggaatata ccgaatttaa gaaaggaaac
      961 tcttggaaga ataaactaca acttactatt gataaagctg ttttaaaatc caaaacttac
     1021 gaggaatttc taaagacaat ggaggatttc ggttatgaaa tcaaaatagg aaaatacctt
     1081 tccttccgac ataaagataa aagagataag ggaagattta ccagagcgaa agcatctact
     1141 ttaggggaag attatacaaa agagagaatc aaggaacgaa tcgaagattc aaataagcaa
     1201 aatatttatg ttaatcagga atatcattat gaaaaacgct cctacaagaa accggatact
     1261 attgtagata tgaaaaacaa tgaaaaggta aaatcatcta agggatatga agtatgggca
     1321 ggtaaacata atatgaaaac tatggcatct gccttaaatg aaatgagaaa atcaggtatt
     1381 aactcctacg aggaattaga tttaaaatta aagaaagtgg catcagatag acaacaatta
     1441 ttggatcata taaagcaaat agaaaaagaa atgaagtc
//
LOCUS       DARYLD010000114         1285 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYLD010000114 DARYLD010000000
VERSION     DARYLD010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1285
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(231..725)
                     /locus_tag="TU651_001920"
                     /pseudo
     CDS             complement(231..725)
                     /locus_tag="TU651_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(951..1023)
                     /locus_tag="TU651_001921"
     tRNA            complement(951..1023)
                     /locus_tag="TU651_001921"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(988..990),aa:Lys,seq:ctt)
     gene            complement(1025..1218)
                     /gene="ssrS"
                     /locus_tag="TU651_001922"
     ncRNA           complement(1025..1218)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TU651_001922"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
BASE COUNT          376 a          226 c          224 g          459 t
ORIGIN      
        1 tgggaggttg tgacaatcga gcggatatcc gatgttatgg cagaactttc tgagtctgaa
       61 taattttagt tcaccaaaga atcaagaaag aaccattggg gcaaaattgg ggcataagtt
      121 tagaactttt gtcgtttctt gtgtcgatac aataccggtt taatactaac aaatgctttt
      181 attatcgact ttgtaaccat tattgttcct tgtgtttttt cgggaataaa ctcaagaagt
      241 ttttgagttt tttcttgaat ttctttttca tatttcaata tgatgagtga aattttatct
      301 tctttggaca tagtgttgtt gtcttcaaga ttaagttctt tagttgttag agtgttttta
      361 tctaatttat tttgaaatat tgcaaaatct agaatttttt gaagtaatac ttcttcctcg
      421 gccatacggc tataaagcca attattttcg agtctctcta ggtgctccat ccacttaaag
      481 tctctttttt ctcctaacat attgtaggga aataaggtat caatatcaac atttaaggct
      541 gtagcaatct cttgaagcct atcccatgaa ggttcagtag tccccttttc gtcattaata
      601 attgtttgct tagtaactcc tattaattta gcgagttctt tttgtgtttt tccagctttt
      661 aagcgagcat ttttaatatc tatttgtcca actgttaaag cctgcgaata attaaaaaaa
      721 gccatttttc tccaaattcc gtcgcaggtg atggaggtga aaatactccg attgtatcac
      781 cttgtgttaa ttatattatt gtcatgtgtt agctctcttt ttaaaaagta ataaattctt
      841 tatttaacat catatcataa aaaattgttt cggggacaaa tggtgggaca aaccctcttt
      901 aggcaagcaa aaaagccctg caataaaggc tttttgtcgt ttttacacta taccccctac
      961 agggctcgaa cctgtgaccc atagattaag agtctactgc tctaccaact gagctaagga
     1021 ggtaaggaaa gctgtattgg caccggtgat tcacgttttg tattgaaccc gcacgatata
     1081 agcaggtggg caacatactt ctcttcagat tgcttccacg tgaaacggct tgcatactag
     1141 agatagactt tgtttcccta aaatacaaaa aaatagtcgg tcaacactta gatgtgaatt
     1201 cgtatgccac agcaataact ctatgctctt atgataccac tttttgaaaa tttttcaagc
     1261 cctaaaatga aaaaaagatc gtatt
//
LOCUS       DARYLD010000115         1268 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYLD010000115 DARYLD010000000
VERSION     DARYLD010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1268
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..>1268
                     /locus_tag="TU651_001923"
     CDS             <1..>1268
                     /locus_tag="TU651_001923"
                     /inference="COORDINATES: protein motif:HMM:NF012873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897866.1"
                     /translation="ELGGVASHVYMEVILPLLDIDRAEKVWNDIILKHDALHSIFTSN
                     NTQKVLKEFAYYKIECNEGADIKEKIALTRDKLKGKSYNADIWPLFDISVSQLDDNSL
                     LHLSFDFLILDWASIWILLKEFEECYFDGKTIMDNSYDLKEIRTSQLKLKHSSKYLSD
                     KDFWERRIPFLPDAPLLPIKNKIVKNGFERIQLRIDENTWSKIKSNISEIGVTQTSFL
                     VTILALVLNRWSSNSEFTINLTTMNRPKEYIKSDVVNDFTSTELLEFRMESLQPFYVL
                     LKHIQQQMIEDLQHETFTGVEVTREVRKNVERRDAIFPFVFTSALGIKASEYKYISLQ
                     KEGLSETPQVLMDCQVMEVNHELIINFDLRADAFSKELSNSIAEDYSNLLNCFFDLEY
                     FKKTLTEMYDENEMNDVLADKSDFDRVKYR"
BASE COUNT          483 a          144 c          233 g          408 t
ORIGIN      
        1 tgaacttggt ggtgttgcca gtcatgttta tatggaagta atattacctc tattggatat
       61 agatcgagct gaaaaggttt ggaatgatat aatactaaag cacgatgcat tacattcaat
      121 atttacatca aacaatactc agaaagtact gaaggaattt gcttactata aaatcgaatg
      181 caatgagggt gcagatataa aagaaaaaat tgcattaaca agggataaac ttaaggggaa
      241 aagttataat gcagatatat ggccactatt cgatataagt gtaagtcagt tagatgacaa
      301 tagtttattg catttatcat ttgatttttt gattttagat tgggcaagca tttggatttt
      361 attaaaggaa tttgaagagt gttattttga cggaaagacg attatggata attcttatga
      421 tcttaaagaa ataagaacga gtcaacttaa actgaaacat agttctaagt atttatcgga
      481 taaagatttc tgggaaagaa gaattccttt tttgcctgac gctccactat taccaattaa
      541 aaataaaata gtcaaaaatg gttttgaaag aatacaactt agaatagatg aaaatacttg
      601 gtcgaagata aaatctaata taagtgagat tggtgtcacg caaacatctt tcttggtgac
      661 aatattagct cttgttctta atagatggag ttctaattct gaatttacca ttaatttaac
      721 aactatgaat agaccaaagg agtatataaa gagcgatgtt gttaatgatt ttacatctac
      781 agaactttta gagtttagaa tggaatctct gcaaccattc tatgttttat taaaacacat
      841 acaacagcaa atgattgaag atttgcaaca tgaaacattt acaggagtgg aagttactcg
      901 tgaagttagg aaaaatgtag aaaggagaga tgctatattt ccatttgttt tcacaagtgc
      961 attaggaata aaagcttcag aatataaata tattagttta caaaaagaag gtttgagtga
     1021 aactcctcaa gtattaatgg attgtcaagt aatggaggta aatcatgaac taataattaa
     1081 ttttgactta agagcagatg ctttttcaaa agaattatca aattcaattg cagaagacta
     1141 ttctaatcta ttaaattgct tttttgattt agaatatttc aaaaaaacac tgacagaaat
     1201 gtacgatgaa aatgagatga atgacgtttt agctgataag agtgattttg atagagtgaa
     1261 atacagag
//
LOCUS       DARYLD010000116         1263 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYLD010000116 DARYLD010000000
VERSION     DARYLD010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1263
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            309..659
                     /locus_tag="TU651_001924"
     CDS             309..659
                     /locus_tag="TU651_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL0897867.1"
                     /translation="MFSTFEKIKELCKSRGISIAKLEENLGLSKNAIYAIKRNQPSAE
                     RLQEIADYFHVSTDYLLGRTDNPKIAQSDHTPSAIDLKKDAEETFFFDGHELNDEDID
                     LITSILETRIKNRK"
     gene            673..1077
                     /locus_tag="TU651_001925"
     CDS             673..1077
                     /locus_tag="TU651_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL0897868.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     TYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLREELSYWDNVEEFNYVR
                     FMQQYDLTSFVDEVMVKEEYYNLTGYYDKKSF"
BASE COUNT          475 a          209 c          206 g          373 t
ORIGIN      
        1 cgatcgggag ttttttattt aaatgaaaag cgaatttttt tgcgaaaaat tttttatagt
       61 ttactcttga caatgattag agaataaact acaatcaaca tatagaaaaa aacactaaca
      121 aatagcttaa taacactaac tatcttaagt cgccaaactt tattttttta gttttatttt
      181 cgctttttgt ttcgcttatt tattcgcttt acaaattata ttttagagta ttctcttgtt
      241 tttgtcaaca ataaaataga tatttctcta aaatattttt cgtgatgctt agaaaggttg
      301 atatatcaat gttttcaaca ttcgaaaaaa tcaaagagct ttgcaaaagt agaggaatct
      361 ctattgcaaa gctagaagaa aatcttggat taagtaaaaa cgctatttac gcaatcaaga
      421 gaaaccagcc gtccgctgaa cgtcttcaag aaatcgctga ctacttccac gtctctacag
      481 attacctttt aggtcgcaca gataatccta aaattgcaca aagtgaccat accccgtctg
      541 caatcgatct aaaaaaagat gcagaagaaa ctttcttctt cgatgggcat gaactcaacg
      601 acgaggatat agaccttatc acatctatat tggaaacgcg catcaaaaat agaaaataga
      661 gaggacagct ctatgatgac accagaaaca gtctgtcagg aaaagggaat cgatttagtg
      721 tacttcgacg gtagggggac aaacacccct ggaatgttta acaaaaaaca caacgtcatt
      781 gcgattgaca cttatcttga cggcacatac aagcacaaag tcatctatca tgaactagga
      841 catagagaac atactgcgag ttattacaag ctaaacaaag aaaaagcaga gctacaagct
      901 gatagatgta tgatacatca cttgctgagg gaagaattgt cttattggga taatgtagag
      961 gaatttaact acgtccgatt tatgcaacaa tacgatctaa cttcatttgt cgatgaagtc
     1021 atggtcaagg aagagtatta taatttaaca ggttattatg acaaaaagag tttttaattc
     1081 tagctttcaa gtagctggaa cagtatatca tcaaacactt attataaaaa tttaacaaat
     1141 aaaaaaatca ttaactatct acagagtagc catacaggca gaatttataa atacaattat
     1201 ctaaaatcaa atgaagttaa attagtacga gagcctaata ataaacatga tcagaatgct
     1261 gtt
//
LOCUS       DARYLD010000117         1258 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYLD010000117 DARYLD010000000
VERSION     DARYLD010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1258
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(146..538)
                     /locus_tag="TU651_001926"
                     /pseudo
     CDS             complement(146..538)
                     /locus_tag="TU651_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(535..1062)
                     /locus_tag="TU651_001927"
     CDS             complement(535..1062)
                     /locus_tag="TU651_001927"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL0897869.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
BASE COUNT          409 a          313 c          245 g          291 t
ORIGIN      
        1 ggtaaagcac tagaaagcac tcaacagcag acaaaatagg agttggggca accgtcctag
       61 aagcattaaa aagcaacagc agcaaaaccg ttgctttttg tttaaatcaa agatacacct
      121 gtcctagcac ttataagctt gaaggaaaaa gaccaaaaag agaggtggaa gcacctgctg
      181 ctacggtatc tggtgtcagc cacatgataa aagcattccc cataatccct gaacacacat
      241 acagcagcaa aaactgtctt gacccccaaa tggtctcagc catccgcccg acaaaataaa
      301 gggttaaggt attaatgaaa aaatgctcaa agccaatatg aaccactata ggtgtcacca
      361 agcgccaaag ctgatcaggc attgctctga caacaagacc attcatgcca ccaaatataa
      421 caacagcata agggtgcgta gcaaactggc catagaccag ctgcattatc aaaaaaacta
      481 aaccagtcaa gcccaagaaa aagagtgtta tcgggtattt tttgatcatc agtctcattg
      541 gcaatacacc tccttcacag caatatcatg tgcctctacc acaaaatcct cccactgaca
      601 ggcataaatc gtgctaaagg tagccccctg ataatccctc aaataacgat catagtagcc
      661 accaccatag cctatacgat agcctgcagg gtgaaaaaca agccctggca catgaatggc
      721 atcaatctcc gacttagcaa cagctatggt acacctaggc tccataagac caaaagccgt
      781 ctgtatcaag tcacaaggat cataagccac aaacaccatc tctccacgag aacgagtctt
      841 gggcacaagg atagtcttgc cgtcctgcaa ggctcgctca atcagtagat ggctttgata
      901 ctcgtgtggc aagggcagat aggtcacaag agtctgcgcc tcttgatagc tgctactagc
      961 aactactgct gccaatagag ctaagtcctt ttccagctta tcctctgggg tcatcatggc
     1021 taggcgctga agcactagtt ggcgataatc ttttttaatc atgcccatat cataacacaa
     1081 agcgctgcta ctattcaaga atcggccaca atcaaggttc tttccttagt tgtcctacca
     1141 gacagggcag cagctcaatc agtgaatgtc cttcttactt cttgaggtga gcttgtggtc
     1201 tcatgagatc aaaaaattat ttttctaggt taagaaaagt ttaagcttta tgctatac
//
LOCUS       DARYLD010000118         1105 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYLD010000118 DARYLD010000000
VERSION     DARYLD010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..297
                     /locus_tag="TU651_001928"
     CDS             <1..297
                     /locus_tag="TU651_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL0897870.1"
                     /translation="NAVNYSVKGTSININVEEINGMLKISVINDVSPNLNVNWNMVTS
                     KFYRGDLSRRISNNGSGLGLTIVNDIVKHLGGNFEIGEENKRVCAKVILPYRLN"
     gene            575..958
                     /locus_tag="TU651_001929"
     CDS             575..958
                     /locus_tag="TU651_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL0897871.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
BASE COUNT          410 a          112 c          242 g          341 t
ORIGIN      
        1 aatgcagtta attattctgt gaaaggaaca agcatcaata taaatgttga ggaaataaat
       61 ggaatgttaa aaataagtgt tataaacgat gtttctccaa atttaaatgt gaattggaat
      121 atggttactt caaagtttta taggggagat ttatcaagac gaataagcaa taatggatcg
      181 ggacttggac ttacaattgt aaatgacatt gtaaaacact tgggtggaaa ttttgaaatt
      241 ggagaggaga ataaaagagt ttgtgctaaa gtaatacttc catatagatt aaattaaatc
      301 gcaaagaaaa cgcaagaatt attcaaagat accgttaagt ataaagcaaa gagctattct
      361 ataatgtgag taaggatagc tcttttatat ttgaaaggaa ttattaattt gaataagcat
      421 ctgtgattat aaatatataa aatggaggtg gagttttatg aattacaata atcctcatag
      481 gtataggaac ggagattgag tagagttttg ggaaacttta ttcggaagaa aaattttaca
      541 aaaaatttaa gtatttgaga gaggagaatt tatcatgaaa aaagcattgt cattagtatt
      601 attaacaggt ttgatgttag catcatctgt accagcattt gcagcagaag aaacaaactt
      661 gccatatgtt gaaggtcttg gttatgaggt ggaagtattt gaagaagatt atactcagcc
      721 aaagttgttc agttatgata gcggatggaa aagtttttta ggtggaaaat ggagacatgg
      781 tgtaggtagt cgatatgttt ggtctaaata cgatcacaat aataaaacac ataaaactac
      841 agtacaaggt gctggtggtc aattctctta ttcgggttgg acaagcgctg gaagtagagc
      901 agaagcttct tgggaaaaag ctttaagtgg taatagggct tgggctgatg ttaaataaca
      961 ataaataaaa aatagttgaa cgagtttgag cggtgccacg ttgttatttt agcattgtgg
     1021 cattactcat actcgctatt tttataaagt tggagatgat acagaatgaa aaaaacagtg
     1081 ggtatattgg caattttact aatta
//
LOCUS       DARYLD010000119         1077 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYLD010000119 DARYLD010000000
VERSION     DARYLD010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            41..>1077
                     /locus_tag="TU651_001930"
     CDS             41..>1077
                     /locus_tag="TU651_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL0897872.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
BASE COUNT          337 a          209 c          228 g          303 t
ORIGIN      
        1 tttttcttgt tgtgtatggt tatatatgtt ataataaact atggctttta ttaaaacaac
       61 aacgaataaa gaaggtagga cgcatgtcta ccttgtagaa gggtatcgta aagatggtaa
      121 ggtcaaacag cgtatcctta aaaaatttgg tctcttagat gagcttgaat tggaagaacc
      181 agggattctt gagcgtctta agcgcgaagc taaagaagat actttaaata accctaaggt
      241 actccaggtt tcctatgacc tccttgcccc catgaaccaa ccggatcaat cttatggttg
      301 gatggttttg gataatctct tcgaatctct ggggctcaca gcctttttaa agggtatcaa
      361 aacgaagtct gagtatgact tagtgcaagt gctaaagcta ttagtttttc agagaattct
      421 ccgaccagat agtaaacttg ccacctatgc ctctcaagca gacttatttg gccattggga
      481 catcagctta aatgccattt atcgctcctt gaacaaattg aacaccttga aagatgatct
      541 tcaacatcat cttcacaagg tagtgagtca gatgatcaaa cgtgaagcca gtctcgtttt
      601 ctacgatgtc accaattatt attttgagac agatattcca gataacgagt tggtttcaga
      661 aaatggagag atactacaag aagggcttcg aagacgtggt ccgagtaagg aacaccgtcc
      721 aaaacccatt gtgcaattag gactctttag ggataccaac ggtattccga ttagctataa
      781 actgtttcga ggtaatcaaa ccgatcctgt tacctatctt ccagcggttg aggaagtcaa
      841 aaaacaattt ggaattgagc ggttaattgt agtcgccgat aaggcgatga atagtatggc
      901 taatgtttca gaaatgctca agcaagaaga tggctggctc ttctcacaga aacatcgcgg
      961 acgccgagga gctccaaaag atattcaaga acacatcctt gattcatcgg attggcaatt
     1021 taacccagaa cttaccttcg ctaagaaatc ttatatccgt gaacggaagt tagggaa
//
LOCUS       DARYLD010000120         1063 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYLD010000120 DARYLD010000000
VERSION     DARYLD010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            104..1063
                     /locus_tag="TU651_001931"
                     /pseudo
     CDS             104..1063
                     /locus_tag="TU651_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          374 a          184 c          233 g          272 t
ORIGIN      
        1 aagttacgat gataaattaa gaatatatga actaagaaaa aatgggatgt cttgttcccg
       61 cattggtcaa cagtatgata ttcaggtttc taatctcaaa tacatggtaa agcttatgga
      121 cagatatgga gttgagattg ttagaaaggg taaaaataag tattatcctc cagaattaaa
      181 acaagaaata attgataaag ttcttcttga aggtcagtct caactgtctg tctctcttga
      241 gtatgctctc ccaaatgctg gtatgcttcc caattggata gcgcaataca agaaaaacgg
      301 gtatactatt cttgagaaac aaagagggag accaacgaag atgggccgta aaccaaagaa
      361 aacttgggaa gaaatgacag agctagagcg ccttcaggaa gagctagaat accttagaac
      421 ggagaatgct tatctaaaaa agttgaggga gcttcgttta caggacgaag ccagagaatg
      481 agaaaggcag aaacaattag agagatggtc caagaaggat tccgattaaa cctcctactt
      541 gagatcgcta agatggctcg ttcaacctat tattatcaag tcaagcaatt ggataagtca
      601 gataaagatg aagcaatcaa ctctgaaatc aaagcgattt atgaggagca taagggaaac
      661 tatggttacc gtcgcattca tttagaactc aagaatcgtg ggtttatcgt caatcacaag
      721 aaagtgcaac gcttgatgaa agagatgaga ttagctgctc gaattcgtcg taaacgcagg
      781 tattcctctt acaaaggcga gactggtaag aaggctgata atctgattca acgccagttt
      841 gaagctgcta agccatatga aaaatgttat accgatgtga cagagtttgc tttaccaaac
      901 aacgatgaaa aactttattt agcgcctgtt cttgatggct acaacagtga gattattgat
      961 ttcacactat ctaggtctcc agacttaaaa caggttcaaa ccatgcttga gaaggctttt
     1021 ccagcggatt cgtacaatgg aacgattctc cacagcgatc aag
//
LOCUS       DARYLD010000121          908 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYLD010000121 DARYLD010000000
VERSION     DARYLD010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(7..492)
                     /locus_tag="TU651_001932"
     CDS             complement(7..492)
                     /locus_tag="TU651_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL0897873.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(581..654)
                     /locus_tag="TU651_001933"
     tRNA            complement(581..654)
                     /locus_tag="TU651_001933"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(618..620),aa:Arg,seq:acg)
BASE COUNT          274 a          261 c          137 g          236 t
ORIGIN      
        1 ccccttttat ttctcaccag taaagtcctg aaagtaaggt cctatcttgc gaagcaaggc
       61 ccgtctcccc tcaaaccgct ctcccctgat caaagcccga aactgcgaca gctcaccctc
      121 tgtcaatcgc tcctcaacct ccttcacaat caactgataa gccacataat catctactcc
      181 caaaccacct gctggtatcg catggcctac cgacccaatc tcctcataag ccatcttatg
      241 aaaccgacgc ttctgactct cctgctgccg caacacgtcc ttcaaataag aggaaaactt
      301 ggtcttaaaa taacgatata gcttctcctc atcctctatc aattctggat aagtgaccaa
      361 taaccgatac aagatcaacc gcccctcctg taaccaatca tctagctccc acagctgaat
      421 ataataatgc tgtcttagct tcataataat aggcttgatc ttatcaaaca acctcactaa
      481 atcatcagtc attatacttt ctccttttca tgcttagtag ccttattata aggagacaaa
      541 caaaaaaaca acaggacaga aatgtcctgt tgccttgcta tgcaccctag aggagtcgaa
      601 cctctaaccg cctgattcgt agtcaggtac tctatccagt tgagctaagg gtgcttttct
      661 taactattac tatcctacca tactatcccc taaaaagcaa ggctctatac catctggaat
      721 aggtaagtcc actgtggaaa tcatagagct ttttgagtac acaaaaaaga gagcaccaaa
      781 ctgatcctct ctaaatgtcc gttgttagtc aacccactat agttgacata gagccaaact
      841 ccgccagtag gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg
      901 agctatgg
//
LOCUS       DARYLD010000122          866 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYLD010000122 DARYLD010000000
VERSION     DARYLD010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(1..291)
                     /locus_tag="TU651_001934"
                     /pseudo
     CDS             complement(1..291)
                     /locus_tag="TU651_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
BASE COUNT          270 a          125 c          144 g          327 t
ORIGIN      
        1 ccaattttac cattaagcct ttgtagataa tcaattggat ctaaaattcc tactgctttt
       61 agtttattaa aggataggta agaattattt tctataatag cctttgcttt aacatagtta
      121 aagtataaaa tatcattaga ataaacagta taatattgtt taaagaagtt tgaaaccaca
      181 ttagtgcctg caaataaatc taaaaaaaac ttcttcatca ccagttttat gtttgtctag
      241 catggtctta atttctgtca acaataattt tttagaacca atatatctca ttctacatcc
      301 ttaatcatcc tttagttgtt tcattatagc atattcatgt tgaagttcca atattttatt
      361 tgaaaaatta tcttttgctg tatttcttta ttgtagtttt taagcttagt ttatatgttg
      421 ttgattaaag ggaagaagaa cttaggttat ctaaattgag gaattcgtct gtaggtaaca
      481 atgtattatg tggccgagag atttatttta tatattaatg agatataaga cccctatccc
      541 gtccagcgtg acagacttgc tatggaaaag cttattttga ggctgtctga ggcttgctta
      601 tgtgtgacaa gcatttaggc tagaacgctc acctttttta ctgcaagcaa agctttagaa
      661 gctattgcaa gatactttta ggcttgttac taagcgggtc atctctatca tctcctagag
      721 agtagtggag gctatgacag tttagcatat atggtttctc taatgatttg acgatgtaaa
      781 accataacta ctgttattgt agggattatg tataatatgt ataaaaagag aagggcttgt
      841 ttctcagcgt tatcatttta cctata
//
LOCUS       DARYLD010000123          826 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYLD010000123 DARYLD010000000
VERSION     DARYLD010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..826
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            145..826
                     /locus_tag="TU651_001935"
                     /pseudo
     CDS             145..826
                     /locus_tag="TU651_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          294 a          146 c          173 g          213 t
ORIGIN      
        1 gacataaaat ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt
       61 caaatctatg agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt
      121 attgcagaat ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt
      181 gtccaaaaag gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa
      241 gttctgattg atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct
      301 agtatgcttt caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa
      361 agaagaggga ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca
      421 gagttggagc gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa
      481 aagctgagag aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc
      541 aagaattaat cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt
      601 caacctatta ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg
      661 agctcattca aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc
      721 tggaactaag aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg
      781 tcatgggctt aaaagctcgt atccgtcgta agcgcaagta ttcttc
//
LOCUS       DARYLD010000124          818 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYLD010000124 DARYLD010000000
VERSION     DARYLD010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(29..778)
                     /locus_tag="TU651_001936"
     CDS             complement(29..778)
                     /locus_tag="TU651_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL0897874.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVIKAIEEFVYSNENI"
BASE COUNT          250 a          172 c           93 g          303 t
ORIGIN      
        1 tagttctttt ttatctgaaa tttctattct atatattttc attggaataa acaaattctt
       61 caattgcttt tatcacactt tcaggagatg tatttacaaa catatgcttg ccattaatat
      121 atctgtaaga gaattctttc gtcgtataat cttgccattt taaaagttct tcaagttcca
      181 tttcttcatc aatatcaccc atcagaccta aaatcttgct attcaatttt tccccttttg
      241 tatcctggta gtcctcatcg ataataaaat cggctcttag tgttggtaaa aaaatcccaa
      301 tcaaatcttt attgtctaat atctcatttg gagtaccatc atatcttctt aacccttcaa
      361 taaatccttc atcatctaaa tgataaatcg gattcggttc cttatagcaa ggggctcgcc
      421 cagctgatat gataattcca ttcggatttg gtaacccatt ttctttaatt ttcagagcca
      481 attcataagc aatcttagtt cccatactat gcccgaaaaa ataataaggt gagttaaaat
      541 caaaagtcat ttttaagtct tcaaacaatc cttttacaag ttcttctatg ttgctaattg
      601 ctttttcaga aaacctgttt tctctccctg gatactgtgc aacgaagaga tttatatctt
      661 taaattgatt accccatctt ctgaatgatg atactccacc acctgcaaat ggaaacacaa
      721 ataaactagc tttcgtgttt tccatttctt tattaacgta ttcgaaccac attcccatca
      781 aaacaccttc catctgatta ttaatatact actagaac
//
LOCUS       DARYLD010000125          815 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYLD010000125 DARYLD010000000
VERSION     DARYLD010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..815
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            121..708
                     /locus_tag="TU651_001937"
     CDS             121..708
                     /locus_tag="TU651_001937"
                     /inference="COORDINATES: protein motif:HMM:TIGR02185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL0897875.1"
                     /translation="MSNKLKGKDLITIGIYTAIYFVINFAFMLAGMIPVMWIMMPSLI
                     ALFTGVPYMMICNKVQKAGAILIMGTVTVLIYYATGQFTTVILATFAVGCILAEIIRA
                     ITRYTSFIGNTLSFALFSIGMIGSPLPIWLFKESFFAHISEVGMSQDYINALEKFTSP
                     AILIGVIILTFICSLVGALIAKRMMNKHFKKAGII"
BASE COUNT          282 a           95 c          148 g          290 t
ORIGIN      
        1 atgaaaatgt attaaaacaa tggaaagata tatgctttgg catttttaca agtcataaag
       61 taaaaaaaga attaattaaa gaatttttat taaaaactac gatgacagag gagaataata
      121 atgagcaata agttaaaagg aaaagattta ataacaatag gcatttatac agcaatttat
      181 tttgtaataa attttgcatt tatgctagct ggaatgatac cagttatgtg gattatgatg
      241 ccttcactga tagctttatt tacaggggtg ccatacatga tgatttgcaa caaagttcaa
      301 aaagctggtg ctattttaat catgggaaca gttacagttt tgatatatta tgcaacagga
      361 caatttacaa cagttattct tgcaactttt gcagtaggtt gtatattagc tgaaattatt
      421 agagcaatta ctagatatac aagttttata gggaatactt tatcatttgc actattttca
      481 attggaatga taggatcgcc tcttcctatt tggttgttta aagaatcatt ttttgctcat
      541 atatcagagg ttggtatgtc gcaggattac ataaatgcct tggaaaagtt tacttcgcca
      601 gcgattttga taggagttat tattttgact tttatttgtt cgttagttgg ggctttgatt
      661 gcgaaaagaa tgatgaataa acattttaaa aaagcgggaa ttatataaaa tgcgtgaata
      721 tagattaaaa atagatccga gagcagggat ttccctgctt tttatcttaa actttacgat
      781 atttaatgta tccacagttt atgcattatt tgtgc
//
LOCUS       DARYLD010000126          796 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYLD010000126 DARYLD010000000
VERSION     DARYLD010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU651_001938"
     CDS             complement(<1..>796)
                     /gene="galU"
                     /locus_tag="TU651_001938"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL0897876.1"
                     /translation="LPATKALAKEMLPIVDKPTIQFIVEEALKAGIEEILVVTGKAKR
                     SIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFV
                     GNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTIAVMRVPHEEVSNYGVIAP
                     QGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIFAILENQAPGAGNEVQLTD
                     AIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKHPQVKDDL"
BASE COUNT          188 a          210 c          198 g          200 t
ORIGIN      
        1 aggtcgtcct tgacctgagg gtgcttgaga gcatagtcaa gtgaggtctt cataaagcca
       61 aacttgtccc caacatcata ccgctctccc ttaaactccc tggcaaaaac ccgctgagtc
      121 ttgttgagct tgtcaatcgc atcggtcagc tgaacctcat tgccagcccc aggcgcctga
      181 ttctccaata tggcaaaaat ctcaggcgtc aacaaataac gtccaataat cgctaagtca
      241 ctaggtgcct catcaggact tggcttctca acaaaggtct ccacactata caagccctta
      301 acagccttcc cttgcggtgc aatcacgcca taattggaaa cctcctcatg cggaaccctc
      361 atcacagcaa tcgttgaggc gtgtgtacag tcataatcct cgataagctg cttggtcaag
      421 ggcttggcac taggattggt aatatccatg aggtcgtctc ctagcatgac cacaaagggc
      481 tcattgccca caaaggcctt ggcttggagg acagcgtccc ctagtcctct agggtggctc
      541 tgacgaatga agtgcaggtt gatggcagtg gtctcatcaa cgagcttgag cagctcggtt
      601 ttgcccttgg cttggagatt gtattcgagc tcgaagttgg agtcaaagtg gtcttcgata
      661 gagcgtttgg ccttgccggt gacgacaaga atctcctcga taccggcctt tagggcttcc
      721 tcgacgatga attgaatggt tggcttatcg acgattggga gcatttcctt ggccagtgcc
      781 ttagtggcag gcagga
//
LOCUS       DARYLD010000127          736 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYLD010000127 DARYLD010000000
VERSION     DARYLD010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            68..670
                     /locus_tag="TU651_001939"
     CDS             68..670
                     /locus_tag="TU651_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897877.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPGYHIARYIDSIDTVPNNNRINLW"
BASE COUNT          245 a           89 c          149 g          253 t
ORIGIN      
        1 gttaaactta aatttttgaa agactagtct aaacatttat ttttaaagaa gggcatggtg
       61 aatcaatatg atttctgtaa agaaaaattt atgtcgctta ggtgttttgt ctagtagttt
      121 attactttta acagctgcaa cgactccatc tgtcattgct tttgcggata ttcaaacaag
      181 tgccataaaa aataatacag atgacgcaga tggtatgtat tttgttcaaa gttatgaaat
      241 gtctgtagaa gataaagaat tgcttgttcg aaatgttaaa gcaaatcatc ctacagtttc
      301 tgaagatttt atcagagaag ttattgaaag acaattagta ggtgattata cattacctga
      361 agaagagact cttttccgct cagcatggca aggggttaca gtagatcaat tgggagcagc
      421 tctagatgtg gctattggta tggcattaac aggtggagct ggatcaattg ctgctggtgt
      481 tttgagagtc ggaaaaagag aagctgttgg tcgggtaaaa tcaattctaa ttaaatatgg
      541 gctaggtaaa atgatagctg aaattccagt cgattacatg ttaaatttat tatcgccagg
      601 atatcatata gctagatata ttgatagtat tgatacagtt cctaataata atagaattaa
      661 cctttggtaa gttaggaaat ttagtactgt gaaaaaaatt tatattttat attttgtgct
      721 ttattgctta ttatac
//
LOCUS       DARYLD010000128          700 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYLD010000128 DARYLD010000000
VERSION     DARYLD010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..426)
                     /locus_tag="TU651_001940"
     CDS             complement(<1..426)
                     /locus_tag="TU651_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897878.1"
                     /translation="MVELKNISYSYSKENQILQDINIKIQDGECILLCGRSGCGKTTI
                     GRIINNLIPRFFERGVMSGDVYINNENTKDFEMHELANLIGTVFQNPKAQFFHTNSDA
                     EIVFGLENNGMKPEKIRRRYKEVVDELNIHDLTNRDMFSI"
     gene            complement(440..>700)
                     /locus_tag="TU651_001941"
     CDS             complement(440..>700)
                     /locus_tag="TU651_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL0897879.1"
                     /translation="LREDFHKTYDAMKLKNMSVLEKISGLIITTMTRATLNIEELSQA
                     ASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYIFICVRY"
BASE COUNT          224 a          136 c           65 g          275 t
ORIGIN      
        1 aatcgaaaac atatccctat ttgtcaagtc atggatattt aattcatcta caacttcctt
       61 atatcttctt cttatttttt ccggtttcat cccgttattt tctaaaccaa atacaatttc
      121 tgcatccgaa tttgtatgaa aaaactgtgc cttaggattt tgaaaaacgg ttccaattaa
      181 attagctagc tcgtgcattt caaaatcttt agtattttca ttatttatat aaacatcacc
      241 tgacataact cctctttcaa aaaaacgagg aattaaatta tttataatcc tacctattgt
      301 tgtctttcca cacccacttc ttccacataa caaaatacat tctccatcct gtattttgat
      361 atttatatct tgtaatattt gattttcttt tgaatatgaa tatgaaatat tttttaattc
      421 aaccatatct atcctccagt caatacctaa cacatataaa aatatagaca acagaagaca
      481 ctataaacac taccgcatca cttgtcttaa aatttatttc agccgcagaa aattttttta
      541 caggattatc tatgcctctt acacttgctg cctgagataa ttcttctata tttaatgtgg
      601 ctcttgtcat tgtagtaatt atcagtccac ttattttttc taaaacagac atatttttta
      661 gtttcatagc atcatatgtt ttatgaaaat cttctcttaa
//
LOCUS       DARYLD010000129          672 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYLD010000129 DARYLD010000000
VERSION     DARYLD010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..672
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..>672)
                     /locus_tag="TU651_001942"
     CDS             complement(<1..>672)
                     /locus_tag="TU651_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL0897880.1"
                     /translation="AGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALAPQKQLTVIG
                     HQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGDTPLIRGESL
                     KALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANEAEQEVKEIN
                     TGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLKDFDESLGVN
                     DRLALA"
BASE COUNT          140 a          183 c          152 g          197 t
ORIGIN      
        1 gctagggcta ggcgatcatt aacccctagg ctctcatcaa aatccttcag caggtaagcg
       61 ccaacccttt cttggccagc cttgaaaata ctgatcacat cggttaggta gtactcccct
      121 tgggcattat cagtcgtgag atgctttaga gcctcaaaga ggcgcttatt gtcaaagata
      181 taagtccctg tgttgatctc cttgacctct tgctctgcct cattagcgtc cttttgctca
      241 acgatattga ccacctctcc tgctacattg cgaatgattc gtccatagcc aaagggatcc
      301 ttggcattgg ctgtgagaat ggttgccaca ttcttttctc tgatatgata gtctagcaga
      361 gccttgagac tttctcctct gatcaagggg gtgtcacctg caatcactag ggtttgtccc
      421 tctaagccag atagctcctc ttctgccatc atgactgcat ggcctgttcc tagctgctcc
      481 tcttgcacca ctgtcagtga ttgatcacct aggacggcac gtacctgctc tgcctgatga
      541 ccgatcactg tgagttgctt ttgaggagct agggctgaga cgctattgag gacatgctcc
      601 agcatgctta agcctgatac cttgtgcagc accttgggaa gccctgattt catgcgggtt
      661 ccctttccag ct
//
LOCUS       DARYLD010000130          664 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYLD010000130 DARYLD010000000
VERSION     DARYLD010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(177..>664)
                     /locus_tag="TU651_001943"
     CDS             complement(177..>664)
                     /locus_tag="TU651_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL0897881.1"
                     /translation="VYLFNDTIENNIKFGNPNVSKEEIINAAKKSHCHEFIMNLPNGY
                     ETIVGEGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPENEYLIQRAISNLSK
                     GKTVIIIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWK
                     I"
BASE COUNT          199 a          144 c           59 g          262 t
ORIGIN      
        1 ctgcatcaaa aaatatgtat tctatgttat ctttcttaat aaaattcata tgacttctcg
       61 atacagcata aatataatta tcttcccatt tagacacttt ttccataaaa agcgaaccta
      121 tattaccatt gcaacctaaa actcctatat tatacataaa cctcctccta tctatattat
      181 attttccagt cctctgtttt acccctgatt ctcatataat ctctatacag accatcttgg
      241 ctcatcagtt ctgtatgctt tcctatttga gcaatctctc cttctttcaa aacaattatc
      301 tgatctgctt cttcaattgt tacaattcta tgagcaataa taattacagt cttaccttta
      361 ctcaaattcg atattgctct ttgaattaaa tattcgtttt caggatctat gcttgatgtt
      421 gcttcatcca aaataataat tggagcatct tttagcattg cccttgctat agatattctt
      481 tgtttttctc caccagataa aaaatcacca ccttcaccaa caatagtttc atatccattt
      541 ggcaaattca ttataaattc atgacaatgt gacttcttcg ctgcatttat tatttcttcc
      601 ttacttacat tcggattacc aaattttata ttgttttcga ttgtatcatt aaacaaatac
      661 acct
//
LOCUS       DARYLD010000131          618 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYLD010000131 DARYLD010000000
VERSION     DARYLD010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..618
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            185..>618
                     /locus_tag="TU651_001944"
     CDS             185..>618
                     /locus_tag="TU651_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL0897882.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKG"
BASE COUNT          244 a          110 c          149 g          115 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaaggg
//
LOCUS       DARYLD010000132          601 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYLD010000132 DARYLD010000000
VERSION     DARYLD010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..153
                     /locus_tag="TU651_001945"
     CDS             <1..153
                     /locus_tag="TU651_001945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897883.1"
                     /translation="YYISVTFMGGEIYTGVEQASKDNEEFLNRRKKAENKTTLSKDIE
                     VIYKEK"
     gene            156..>601
                     /locus_tag="TU651_001946"
     CDS             156..>601
                     /locus_tag="TU651_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897884.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITA"
BASE COUNT          205 a          107 c          125 g          164 t
ORIGIN      
        1 tactatatat ccgtaacgtt tatgggaggt gagatttata caggtgtaga gcaagcttca
       61 aaagacaatg aggaattttt aaatcgtcga aaaaaagcag agaataagac aaccttgagt
      121 aaggacattg aagttattta taaggagaaa tagtagtggt tagtgataaa gattataata
      181 aactctctga aaaagtatat gatgttgatg ctaataaagt aactatttct gttagaaaaa
      241 atacggatat tcttaatcgt tatgtcaaaa tcctcaaagc cgaagatacc cccgacaatg
      301 gtatgcaagc tatggctgtt gtaccaataa aagatggcaa agaggataga agtcatatcg
      361 tcattgccta tgccgggaca aatagcagtg atatacgcga tattgacacc gatattcaat
      421 ccgttgtttt tggagatgat caatacctgt gtacccatga ggagcctgat tcttttaaag
      481 tggtcaagag tcagctaagt actgctaaag ccttttccga ctacattagg acaagctacc
      541 ctaacgctgc catctcctac accggacact ctctgggagg ctatctggca ctcatcacag
      601 c
//
LOCUS       DARYLD010000133          582 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYLD010000133 DARYLD010000000
VERSION     DARYLD010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..582
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            145..399
                     /locus_tag="TU651_001947"
     CDS             145..399
                     /locus_tag="TU651_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897885.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            418..>582
                     /locus_tag="TU651_001948"
     CDS             418..>582
                     /locus_tag="TU651_001948"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897886.1"
                     /translation="MKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQER
                     AAIYLSNTYEN"
BASE COUNT          232 a           68 c          125 g          157 t
ORIGIN      
        1 aaatggaagt tacatttttt aatttaaatg atgatacaga taactatgtt attagttgga
       61 atgggaaatt aagtttgata gacaaaaatc ctataactca tttaagttca atagataaaa
      121 taaaagtaaa atattggagt aacaatgata gtaacagata aaaattataa tgatatagcc
      181 gatggggttt ataaggttga tgctggcaaa gttattagac cttggcgaaa cggtaagact
      241 tttaaaacta acgggaaaga ttaccgcgtc ctcaaaacag aagacaaccc cgacaatggt
      301 atgcaggcta ttgctgtagc tccgattaag ggtagtgagg tgggtaagag tcatatcatg
      361 attgtttatg taaaaagcag ctattggcta gcgtcctagc aataaaagga gttgatgatg
      421 aaaaagcaac aaagcaaacg acggaaacta attggcatag tggctttaat aacaatttta
      481 ggaggaatac taacaatgaa ttggtttaat gacgaaaaac taaatagaga gcgtagagaa
      541 caagagaggg cagctattta tttaagtaat acatatgaaa at
//
LOCUS       DARYLD010000134          569 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYLD010000134 DARYLD010000000
VERSION     DARYLD010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            <1..>569
                     /locus_tag="TU651_001949"
     CDS             <1..>569
                     /locus_tag="TU651_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="equibactin biosynthetic protein"
                     /protein_id="HEL0897887.1"
                     /translation="LSINIGKTEVIIKAFNEMGRKNLDTDMRMLFSMTVGYASGRLTL
                     SSPLGPVLWEQSPNVPKIDLIPRFLDGNDNEGCSKPWLSILYEGDTYYKSYVYRNIWV
                     EAIMDDLKEFVFEDKSKKQSNSMKIQHQLETSILWQKIMNSLGYPKQKSLCRNKYIDP
                     DKFKRNEVSCYSIRESVDELNTVCRDTMF"
BASE COUNT          216 a           59 c          110 g          184 t
ORIGIN      
        1 ttatctataa atattggtaa aacagaggtt attataaagg catttaatga aatgggtagg
       61 aaaaatttag atacggatat gcgtatgctt ttttctatga ctgtgggata tgcgtctggt
      121 aggctaactt tatcaagtcc tcttggacca gttttatggg aacaatcacc taatgtacct
      181 aaaatagatc ttataccaag atttttagac ggcaatgata atgaaggatg tagtaaacct
      241 tggttatcaa ttctttatga gggagataca tattataaat catatgtata tagaaatatt
      301 tgggttgaag caataatgga cgatttgaaa gagttcgttt ttgaggacaa aagtaaaaaa
      361 caaagtaata gtatgaaaat tcaacaccaa ttggaaactt ctatattatg gcaaaaaatt
      421 atgaatagtt tagggtatcc taaacaaaaa tcattatgta ggaataaata tattgatcct
      481 gataaattta agagaaatga agtgtcatgt tacagcataa gagaatctgt agatgagttg
      541 aatacagttt gtagagatac aatgtttta
//
LOCUS       DARYLD010000135          539 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYLD010000135 DARYLD010000000
VERSION     DARYLD010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(<1..>539)
                     /locus_tag="TU651_001950"
     CDS             complement(<1..>539)
                     /locus_tag="TU651_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL0897888.1"
                     /translation="TVFNAPSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYL
                     GDDELGISRWVDGKAGIGRHSLAAYRFNSKGQVIDRKGHPAAAQAPALATLRSRLTDY
                     RRLKKQYAASNGISSSEEFYLDQFQSRAVAQALEQTTQLAQEEIIARRKEAVAEAEAL
                     HQKTRDMPFFVSELSWAEL"
BASE COUNT          130 a          138 c          127 g          144 t
ORIGIN      
        1 tctagctccg cccagctcaa ttcactcaca aaaaagggca tgtctcttgt cttttggtga
       61 agtgcctctg cctctgcaac cgcctccttc cgacgagcaa tgatctcctc ttgggcaagc
      121 tgagtggtct gctccaaagc ctgtgcgact gctcgagact gaaattgatc aaggtaaaac
      181 tcctctgagc tactaatacc gttagaagcg gcatactgtt tcttaagccg gcgataatcg
      241 gttagtctgg atcttagggt agcaagagca ggtgcttgag cagcggcagg gtgaccctta
      301 cggtcaatca cctgcccctt tgagttgaag cgataagcgg ctaagctatg acgtcctatt
      361 cccgccttac catcaaccca tcttgaaatc ccgagctcat catctccaag gtaagtgcct
      421 aggtttccaa tgtagtcatt gttaatgcgg tagctgtgat agagtccctt gttggcttta
      481 acaaagtcaa tagcctcctt ggagaggtta ttaacagagc ttggcgcatt aaagacagt
//
LOCUS       DARYLD010000136          499 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYLD010000136 DARYLD010000000
VERSION     DARYLD010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            complement(275..>499)
                     /locus_tag="TU651_001951"
     CDS             complement(275..>499)
                     /locus_tag="TU651_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL0897889.1"
                     /translation="IQGQGEHGHKGHHGKDAKPSAPKADSKSTAKAMAPAAQKGTLPA
                     TGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          120 a           92 c          117 g          170 t
ORIGIN      
        1 gaaattagcg catagaaaaa acgtatcagt tacgattata gtctagtttg tctttatgaa
       61 atatagataa cactgtacaa tccttttctt ttattgtacg actttataca aagaaaagcc
      121 cttggaaatt attttctaag gacttttttc aatttgagag gctggtgata gcctcttttt
      181 gaacttaggt catcttctta gggcaatgct gcctgaagag atgagaaaag ctgttactag
      241 ctcattgcct aaggggaaag gtgcaatggc tggtttagtt tttcttgcct tttaatgtta
      301 gcatgccggc gctagcgata acaccaaggg ctgcaagggt gaagaatggg tgatttgtct
      361 cccctgtagc tggcagtgtg cccttttgag ctgctggcgc catagctttt gctgttgatt
      421 tagaatctgc tttaggtgct gatggcttag catcttttcc atggtgaccc ttatgtccat
      481 gctcgccttg gccttggat
//
LOCUS       DARYLD010000137         4044 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN35848965-rid18538423.guided.092, whole genome shotgun sequence.
ACCESSION   DARYLD010000137 DARYLD010000000
VERSION     DARYLD010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN35848965
            Sequence Read Archive: SRR25004181
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-JUN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001787526.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001787526.1
            Genome Coverage       :: 133x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/23/2023 20:00:53
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 1,955
            CDSs (total)                      :: 1,925
            Genes (coding)                    :: 1,843
            CDSs (with protein)               :: 1,843
            Genes (RNA)                       :: 30
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 23
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 30 of 82
            Pseudo Genes (incomplete)         :: 29 of 82
            Pseudo Genes (internal stop)      :: 30 of 82
            Pseudo Genes (multiple problems)  :: 7 of 82
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4044
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN35848965-rid18538423.guided.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: KS"
                     /collection_date="2021-04-21"
                     /collected_by="Kansas State University Veterinary
                     Diagnostic Laboratory, Manhattan, KS"
     gene            19..1740
                     /locus_tag="TU651_001952"
     CDS             19..1740
                     /locus_tag="TU651_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL0897890.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            1742..2905
                     /locus_tag="TU651_001953"
                     /pseudo
     CDS             1742..2905
                     /locus_tag="TU651_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            3057..3833
                     /locus_tag="TU651_001954"
     CDS             3057..3833
                     /locus_tag="TU651_001954"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL0897891.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            3826..>4044
                     /locus_tag="TU651_001955"
     CDS             3826..>4044
                     /locus_tag="TU651_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL0897892.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLK"
BASE COUNT         1232 a          681 c          923 g         1208 t
ORIGIN      
        1 tcagaaatgg aggatatgat gctgacctta attgttcaac atattaagca aaagaaatgg
       61 atttatatcc ttattgcaat gactttagtg atatatgatg cctcacttgt gataccaaca
      121 agggttattc aagacttggt tgatttgatg tcaaggcatc agctaagctc aggggcattg
      181 gtgaggcatg ttatcattct tttggctacg gcagtagtgt cttatggggt tgcttatttg
      241 tggcatcttc atttatttca ggaggcagtt cattttaagt ttgatattca gcagcgtgcc
      301 tttcgaaagc ttgtttttat gagaacgcct ttttatgaga aatttcgctc aggtgacatg
      361 atcacgcgtt tttcaacaga tgtcgaagca cttatggacc ttatcggcta tggcttgatg
      421 attatcctat atgctggtgg tatgattgct tttattattc cgaccatgtt tttgatttct
      481 tggaaaatga ccttgatagg aatagtaccg attttgctta tgatggtgat gatctatggt
      541 gtgacgaaaa agcaagagca tttggttgaa gaggcgcgtg aggcgatttc aagccttagt
      601 gatgaggtac tagaaaccgt tgagggcatt agagtgatgc gtgcttacag taaaaaagat
      661 tatttggcac ttcattttgc tcaaaagact cagaatttgg cagataaatg gaatcaggtg
      721 gccaagtatc gtgccttgta ctttcctctt tacagcgtca tgattgccat tagtacagta
      781 atcattttaa tggtaggcct acagctcata gcaagctcag aggtaacact tggtcaagtc
      841 attgcgctgc agctttatct ggtgtctttg gtggagccct ttggcatgct gtcagacttt
      901 attttggttt atcagacagg aaagacctct tttggtaaga ttaatgaact catcgaaaca
      961 agtgatgata tggagcctga tggccagctt gagttagaga gctttgatca gattgctttt
     1021 atagactata gctttaccta tgccaatagt tctaggccta gcttagaaaa gatcaattta
     1081 accctgaaaa agggacaaac cttagggatt gttggtaaaa caggctctgg taaaacaacc
     1141 cttgtcaggc agtttttgag acaataccct cttgggcagg ggcagctgat gattaatcat
     1201 cgtagtgtct tggattataa gcgtcaatca cttgagcgtc aaattggcta tgtgccacag
     1261 gagcatatcc tgttttcaaa aacggttgct caaaacattg cgatggggaa aaaggcagct
     1321 acaactgagg aaatcttgga ggcgattgaa actgcggcct ttacgcgtga tgttcaagga
     1381 atggcaaagg gcttggatac tgagattgga gagcgtggtc tgtctatttc aggaggtcaa
     1441 aagcagcgta tttcgattgc cagagccttt ttgtcccagc cagatttgct gattttagat
     1501 gattccctgt cggcagttga tgctagaaca gagactgata ttattcgaca cattcaagac
     1561 gaaagaaagg gaaagacaac acttattgtt agccatcgct tgtctgcgat tcagcatgcc
     1621 gattgggtta ttgttctgga tcaggggcag atagtagagg aaggtcagcc ccaacaactt
     1681 ttagctcaga agggctggta ttatgaacag taccagcgtc agcaggctca ggaggtttaa
     1741 gatgacccta tttataaaat taataaaaga aattaaagct gtgaccttgg ctttttccct
     1801 ggcaataggc tttttgctag tggcaacagc tggaggtcag atggctccct tattgttgca
     1861 acaaacgatt gatcattact tgactccgat agctagagga aaagaggtac cgattgaagg
     1921 ctttcagcgc ttgctcctgc tgtatttgct gttaattgtg ataacagcag ttttgcgtta
     1981 tatctcttat cgaatgctgg tttattcctc taataggatc gttgctaatc ttcgtaatcg
     2041 agcctttgat gtcatgcaga ggctgccgat agcttatttt gatcatcagc ctgcaggaaa
     2101 gattgcaact aggattgtta atgatactga aaccctgaag aatcaatttt atgataacct
     2161 tttgtctcaa attattgtca gtctttcaca aattattttt atttatgtgg tgatgattta
     2221 ccttgatgtg aagtcaggct tgctgttgct gcttattatg ccactctttt atggcatgca
     2281 atggctgtat aaaagcttga ctgaccagcc aatgaaggat ttttatcagg ctaggagcgc
     2341 tgtcaacaca caagtcaacg aaaccatgaa tggtgtttct attattcagc tttatcatca
     2401 agaggatacg atcttagagg aatttgaaga gcagatccac cagatgaaaa cagctgatga
     2461 taggattatt tttgcagagt cagttgcttc atggaccctg acggaattgg taaagtatgg
     2521 catgattgcc gctattttgg ctgttattgg ttaccagttc ttgcagggga gatcaggcat
     2581 cacagttggt aagctcttta tttacgtcaa ttatttgctg cgcttgtttg atttattaag
     2641 tatgctggtt aggcagctac ctaatattca gcgctcaaca gcgacaggaa cgcgcctaat
     2701 gaagctgctt gaggcgcaga cagagccgga taaagcacga gcaattgagc taacagatgg
     2761 tactgtggat tttaccaagg tgtattttgc ttacgaaaat ggcaagacag ttttatctga
     2821 tattaccatt catgctgata aaggggagac ggttgcccta gtagggcata ctggctctgg
     2881 ggacaatgct ataatgatga tagtacaata aatccaagta aaatcaatgg ttaaaggctt
     2941 ccgcaaaact tttaaacttg atgatggatt gaggctatca tcttttttta tatctaaaat
     3001 tatataaaag tatagcataa aatgaaatct ctgtatagag aagaaggagg gactttatgg
     3061 cagaagtgat aaccatagcc aatcgaaaag gcggagttgg aaaaacaact acaactctaa
     3121 accttgccta ttcactaaaa gaactgggga aaaaagtatt agtcattgac cttgatccac
     3181 aagctaatct tacaagatgt tttgatatgg gaaatacaga aaatataaaa accatagggc
     3241 atttgttaat ggtagaactg gaggaagaag aaagctattt ggtagagggc tataccaaat
     3301 cttatgatga gatagatatt atcccctcaa gcattttctt atccgccgtt gaaacacaaa
     3361 tgagagcaga aacaggaagt gaacgtatat tatcggaaat tattaggagg gtaaaagaga
     3421 attatgacta tattctcata gatacatcac catcacttag tgttttgact ataaatgctc
     3481 tttgtgcctc agacagtgtc cttatagtag cggatacaca gctgttcgca gttgttggaa
     3541 tcaatgaact tttaaaaact gttcaaaaaa taaaaaagag agtgaatccg aaactgaaag
     3601 tgcaggggat tttactaacc atgtgtgaga atagaaccaa tctgtccaaa acactgatgg
     3661 agcaagtaga agaaatgttc caaaagaaaa tcaaggtctt tcaaaccaaa attccgaaaa
     3721 cagttaaagt tggggaagcc atctatagcg ggcaaagcat aaaaaaatat gcaaaaggca
     3781 gtagtgtaga cattgcctat gacaatctgg caaaggagat ctgctatgag taaaaaactt
     3841 ctaaagagag aaatcaccga tgccgtagat tttttgcttg atgatggaaa tgccttggaa
     3901 caaggaaata tacagaatat agaacttgat ttgcttgaaa attatcataa tcatccgttt
     3961 actttatata caggtaagag attagacgat atggtagaga gcattaagga aaacggagtt
     4021 cttaatccaa ttatcgtctt gaaa
//
